transforming-growth-factor-beta has been researched along with Klatskin-Tumor* in 1 studies
1 other study(ies) available for transforming-growth-factor-beta and Klatskin-Tumor
Article | Year |
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Forkhead box M1 recruits FoxP3
Hilar cholangiocarcinoma (HCCA) is a malignancy related to chronic biliary tract inflammation. Tumor immune escape is a necessary process of tumorigenesis. Forkhead box M1 (FoxM1) could affect the progression of various carcinomas. This study attempted to elaborate on the mechanism of FoxM1 in HCCA immune escape.. HCCA cell lines were collected to measure the expression of FoxM1 and FoxP3. CD8. FoxM1 and FoxP3 were overexpressed in HCCA cells. The co-culture of CD8. FoxM1 bound to the FoxP3 promoter region to promote FoxP3 transcription and recruited FoxP3 Topics: Animals; Bile Duct Neoplasms; CD8-Positive T-Lymphocytes; Forkhead Transcription Factors; Humans; Klatskin Tumor; Mice; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2022 |