transforming-growth-factor-beta and Crush-Syndrome

Acute kidney injury is the most serious complication of crush syndrome. Hydrogen sulfide (H. NaHS reduced kidney injury molecule-1, neutrophil gelatinase-associated lipocalin, tumor-necrotizing factor-α, transforming growth factor-β, total oxidant status levels, and increased total antioxidant status levels in kidney 3 and 24 h after decompression. Serum urea, creatinine, and creatine kinase levels also reduced with NaHS. NaHS decreased renal damage and apoptosis in crush-related acute kidney injury.. These results suggest that H

Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Cell Adhesion Molecules; Crush Syndrome; Disease Models, Animal; Drug Evaluation, Preclinical; Kidney Function Tests; Lipocalin-2; Lipocalins; Male; Oxidative Stress; Proto-Oncogene Proteins; Rats, Wistar; Sulfides; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha