trans-metanicotine has been researched along with Amnesia* in 1 studies
1 other study(ies) available for trans-metanicotine and Amnesia
| Article | Year |
|---|---|
Antiamnestic effect of alpha7-nicotinic receptor agonist RJR-2403 in middle-aged ovariectomized rats with Alzheimer type dementia.
The effects of chronic combined treatment with alpha7-nicotinic cholinergic receptor agonist RJR-2403 (1.0 mg/kg intraperitoneally) or alpha7-nicotinic cholinergic receptor antagonist mecamylamine (1.0 mg/kg intraperitoneally) and 17beta-estradiol (0.5 microg per rat intramuscularly) for 10 days on passive avoidance retention were studied in middle-aged (15 months) ovariectomized rats with experimental Alzheimer type dementia. Chronic treatment with RJR-2403 and 17beta-estradiol had a pronounced antiamnestic effect under conditions of Alzheimer type dementia in middle-aged ovariectomized rats. Topics: Acetylcholine; Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Drug Therapy, Combination; Estradiol; Female; Mecamylamine; Nicotine; Nicotinic Agonists; Ovariectomy; Rats; Rats, Wistar; Receptors, Nicotinic | 2006 |