Compounds > trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride
Page last updated: 2024-08-21

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and Niemann-Pick Disease

trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride has been researched along with Niemann-Pick Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arima, M; Sakuragawa, N; Watanabe, K1
Sakuragawa, M1
Barranger, JA; Brady, RO; Kuwabara, T; Pentchev, PG; Sakuragaw, M; Sakuragawa, N1
Lüllmann, H; Lüllmann-Rauch, R1
Sakuragawa, N; Yoshikawa, H1
Yoshikawa, H1

Other Studies

6 other study(ies) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and Niemann-Pick Disease

ArticleYear
[Experimental Niemann-Pick rat: additional studies on the specificity of the sphingomyelinase reduction in rats treated with AY 9944 (author's transl)].
    No to shinkei = Brain and nerve, 1981, Volume: 33, Issue:3

    Topics: Aging; Animals; Brain; Cyclohexanes; Humans; Liver; Lysosomes; Niemann-Pick Diseases; Phosphoric Diester Hydrolases; Rats; Sphingomyelin Phosphodiesterase; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1981
Niemann-Pick disease-like inclusions caused by a hypocholesteremic agent.
    Investigative ophthalmology, 1976, Volume: 15, Issue:12

    Topics: Animals; Cyclohexanes; Disease Models, Animal; Eye Diseases; Humans; Inclusion Bodies; Niemann-Pick Diseases; Optic Nerve; Optic Nerve Diseases; Rats; Retina; Retinal Diseases; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1976
Niemann-Pick disease experimental model: sphingomyelinase reduction induced by AY-9944.
    Science (New York, N.Y.), 1977, Apr-15, Volume: 196, Issue:4287

    Topics: Animals; Body Weight; Cholesterol; Cyclohexanes; Depression, Chemical; Disease Models, Animal; Humans; Inclusion Bodies; Liver; Lysosomes; Niemann-Pick Diseases; Phospholipids; Phosphoric Diester Hydrolases; Rats; Sphingomyelin Phosphodiesterase; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1977
Niemann-Pick disease experimental model.
    Science (New York, N.Y.), 1978, May-05, Volume: 200, Issue:4341

    Topics: Animals; Cyclohexanes; Disease Models, Animal; Humans; Niemann-Pick Diseases; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1978
Removal of lipoprotein fraction from culture media corrects the reduction of acid sphingomyelinase activity induced by AY9944.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:1

    Topics: Adult; Cell Line; Cholesterol; Culture Media; Fibroblasts; Humans; Lipoproteins; Niemann-Pick Diseases; Sphingomyelin Phosphodiesterase; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1992
Effects of drugs on cholesterol esterification in normal and Niemann-Pick type C fibroblasts: AY-9944, other cationic amphiphilic drugs and DMSO.
    Brain & development, 1991, Volume: 13, Issue:2

    Topics: Cations; Cells, Cultured; Cholesterol Esters; Dimethyl Sulfoxide; Esterification; Fibroblasts; Histocytochemistry; Humans; Lipids; Niemann-Pick Diseases; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

1991