trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride has been researched along with Epilepsy, Absence in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 16 (69.57) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeon, D; Jeong, Y; Jung, S | 1 |
| Bercovici, E; Cortez, MA; Snead, OC; Wang, X | 2 |
| Cortez, MA; Huo, JZ; Snead, OC | 1 |
| Ahmed, M; Burnham, WM; Chan, KF; Chieverton, L; Liu, RR; Scott, BW; Wong, G; Wood, J | 1 |
| Cortez, MA; Snead, OC; Stewart, LS | 1 |
| Chu, K; Jeon, D; Jung, KH; Jung, S; Kim, BS; Lee, D; Lee, SK; Seo, JS | 1 |
| Burnham, WM; Cortez, MA; Likhodii, SS; Murphy, P; Serbanescu, I; Snead, OC | 1 |
| Cortez, MA; Persad, V; Snead, OC; Ting Wong, CG; Wang, YT | 1 |
| Cortez, MA; Cunnane, SC; Ryan, MA; Serbanescu, I; Shukla, R; Snead, OC | 1 |
| Cortez, MA; McKerlie, C; Serbanescu, I; Snead, OC | 1 |
| El-Beheiry, M; Khokhotva, V; Kokarovtseva, L; Leshchenko, Y; Perez Velazquez, JL; Proulx, E; Snead, OC | 1 |
| Fisher, RS; Huguenard, JR; Kraus, A; Li, H; Wu, J | 1 |
| Burnham, WM; Chan, KF; Cortez, MA; Jia, Z; Snead, OC | 1 |
| Bercovici, E; Cortez, MA; Mistry, N; Persad, V; Serbanescu, I; Shukla, R; Snead, OC; Stewart, LS | 1 |
| Fisher, RS; Huguenard, JR; Li, H | 1 |
| Bercovici, E; Cortez, MA; Snead, OC | 1 |
| Dominguez, LG; Huo, JZ; Leshchenko, Y; Snead, OC; Velazquez, JL | 1 |
| Fisher, RS; Smith, KA | 1 |
| Cortez, MA; Persad, V; Snead, OC | 1 |
| Cortez, MA; Cunnane, SC; Snead, OC | 1 |
| Snead, OC | 1 |
| Bierkamper, GG; Smith, KA | 1 |
1 review(s) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and Epilepsy, Absence
| Article | Year |
|---|---|
Pharmacological models of generalized absence seizures in rodents.
Topics: Animals; Disease Models, Animal; Epilepsy, Absence; Isoxazoles; Penicillins; Pentylenetetrazole; Rodentia; Sodium Oxybate; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1992 |
22 other study(ies) available for trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride and Epilepsy, Absence
| Article | Year |
|---|---|
Epileptic activity during early postnatal life in the AY-9944 model of atypical absence epilepsy.
Topics: Animals; Animals, Newborn; CA1 Region, Hippocampal; Calcium Channels, T-Type; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Voltage-Gated Sodium Channels | 2015 |
Monoamine variability in the chronic model of atypical absence seizures.
Topics: Animals; Animals, Newborn; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrochemistry; Electroencephalography; Epilepsy, Absence; Male; Neurotransmitter Agents; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2009 |
GABA receptor proteins within lipid rafts in the AY-9944 model of atypical absence seizures.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Brain; Cholesterol; Disease Models, Animal; Epilepsy, Absence; Gene Expression Regulation, Developmental; Male; Membrane Microdomains; Membrane Proteins; Protein Subunits; Protein Transport; Rats; Rats, Long-Evans; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2009 |
Cytogenesis in the adult rat dentate gyrus is increased following kindled seizures but is unaltered in pharmacological models of absence seizures.
Topics: 4-Butyrolactone; Animals; Animals, Newborn; Anticholesteremic Agents; Bromodeoxyuridine; Cell Count; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Gene Expression Regulation; Kindling, Neurologic; Male; Nerve Tissue Proteins; Neurogenesis; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2010 |
Environmental enrichment improves behavioral outcome in the AY-9944 model of childhood atypical absence epilepsy.
Topics: Animals; Anticholesteremic Agents; Anxiety; Behavior, Animal; Brain Waves; Disease Models, Animal; Electroencephalography; Environment; Epilepsy, Absence; Exploratory Behavior; Female; Male; Maze Learning; Mice; Mice, Inbred C3H; Odorants; Pregnancy; Recognition, Psychology; Smell; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2012 |
Social deficits in the AY-9944 mouse model of atypical absence epilepsy.
Topics: Aggression; Animals; Anxiety; Conditioning, Operant; Electrodes, Implanted; Electroencephalography; Electrophysiology; Epilepsy, Absence; Exploratory Behavior; Fear; Interpersonal Relations; Learning; Male; Mice; Mice, Inbred C57BL; Smell; Social Behavior; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2013 |
Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet.
Topics: Acetone; Amygdala; Animals; Anticonvulsants; Ataxia; Brain Chemistry; Convulsants; Diabetes Mellitus; Diet; Dose-Response Relationship, Drug; Electroshock; Epilepsy, Absence; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2003 |
Hormonal regulation of atypical absence seizures.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Blotting, Western; Cell Line; Disease Models, Animal; Electroencephalography; Embryo, Mammalian; Epilepsy, Absence; Estrous Cycle; Female; Functional Laterality; Hormones; Humans; Kidney; Male; Organophosphorus Compounds; Pregnancy; Protein Binding; Rats; Rats, Long-Evans; Receptors, GABA-B; Sex Characteristics; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Transfection; Tritium | 2004 |
Lovastatin exacerbates atypical absence seizures with only minimal effects on brain sterols.
Topics: Animals; Body Weight; Brain; Cholesterol; Dehydrocholesterols; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Epilepsy, Absence; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Models, Biological; Rats; Rats, Long-Evans; Sterols; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2004 |
Refractory atypical absence seizures in rat: a two hit model.
Topics: Animals; Anticholesteremic Agents; Brain; Disease Models, Animal; Drug Resistance; Electroencephalography; Epilepsy, Absence; Female; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2004 |
Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional coupling.
Topics: Animals; Animals, Newborn; Brain Mapping; Carbenoxolone; Disease Models, Animal; Electrodes; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Functional Laterality; Gap Junctions; Methylamines; Rats; Rats, Long-Evans; Spectrum Analysis; Thalamus; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
Serotonin depletion attenuates AY-9944-mediated atypical absence seizures.
Topics: Animals; Anticholesteremic Agents; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy, Absence; Fenclonine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Long-Evans; Serotonin; Serotonin Antagonists; Synaptic Transmission; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
Selective changes in thalamic and cortical GABAA receptor subunits in a model of acquired absence epilepsy in the rat.
Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Blotting, Western; Cerebral Cortex; DNA Primers; Electroencephalography; Epilepsy, Absence; Immunohistochemistry; Rats; Rats, Long-Evans; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA; Somatosensory Cortex; Thalamic Nuclei; Thalamus; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.
Topics: Animals; Anticholesteremic Agents; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Absence; Ethosuximide; Female; GABA Antagonists; GABA-B Receptor Antagonists; Hippocampus; Learning Disabilities; Maze Learning; Memory Disorders; Organophosphorus Compounds; Rats; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
Daily rhythms of seizure activity and behavior in a model of atypical absence epilepsy.
Topics: Animals; Anticholesteremic Agents; Behavior, Animal; Cerebral Cortex; Circadian Rhythm; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Male; Mice; Mice, Inbred C3H; Movement; Rats; Rats, Long-Evans; Seizures; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2006 |
Gender and age differences in expression of GABAA receptor subunits in rat somatosensory thalamus and cortex in an absence epilepsy model.
Topics: Age Factors; Animals; Anticholesteremic Agents; Disease Models, Animal; Epilepsy, Absence; Female; Gene Expression Regulation, Developmental; Intralaminar Thalamic Nuclei; Male; Protein Subunits; Rats; Rats, Long-Evans; Receptors, GABA-A; RNA, Messenger; Sex Characteristics; Somatosensory Cortex; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Ventral Thalamic Nuclei | 2007 |
5-HT2 modulation of AY-9944 induced atypical absence seizures.
Topics: Amphetamines; Animals; Anticholesteremic Agents; Epilepsy, Absence; Ketanserin; Piperazines; Rats; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Serotonin Receptor Agonists; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2007 |
Typical versus atypical absence seizures: network mechanisms of the spread of paroxysms.
Topics: 4-Butyrolactone; Action Potentials; Animals; Cerebral Cortex; Cortical Spreading Depression; Cortical Synchronization; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; Hippocampus; Models, Neurological; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Recruitment, Neurophysiological; Synaptic Transmission; Thalamus; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2007 |
The selective GABAB antagonist CGP-35348 blocks spike-wave bursts in the cholesterol synthesis rat absence epilepsy model.
Topics: Animals; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Epilepsy, Absence; GABA Antagonists; Male; Organophosphorus Compounds; Rats; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1996 |
A chronic model of atypical absence seizures: studies of developmental and gender sensitivity.
Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Disease Models, Animal; Epilepsy, Absence; Female; Male; Pregnancy; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Maturation; Time Factors; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2002 |
Brain sterols in the AY-9944 rat model of atypical absence seizures.
Topics: Animals; Anticholesteremic Agents; Brain Chemistry; Cholesterol; Dehydrocholesterols; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Female; Male; Phospholipids; Pregnancy; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 2002 |
Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin; Rats; Seizures; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride | 1990 |