Compounds > tranexamic acid
Page last updated: 2024-11-05

tranexamic acid and Wounds and Injuries

tranexamic acid has been researched along with Wounds and Injuries in 216 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.

Research Excerpts

ExcerptRelevanceReference
"To examine whether the effect of tranexamic acid on the risk of death and thrombotic events in patients with traumatic bleeding varies according to baseline risk of death."9.16Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. ( Brohi, K; Coats, T; Hunt, BJ; Lecky, F; Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H; Willett, K, 2012)
" 20,211 adult trauma patients with, or at risk of, significant bleeding were randomly assigned within 8 h of injury to either tranexamic acid (loading dose 1 g over 10 min followed by infusion of 1 g over 8 h) or placebo."9.15The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. ( Afolabi, A; Brohi, K; Coats, T; Dewan, Y; Gando, S; Guyatt, G; Hunt, BJ; Morales, C; Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H; Woolley, T, 2011)
"Tranexamic acid, an antifibrinolytic agent, reduces postoperative transfusion requirements but carries a poorly documented risk of thrombosis."8.89Trauma and severe bleeding. Tranexamic acid within one hour to reduce mortality. ( , 2013)
"Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth."8.02Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial. ( Davenport, R; Frimley, L; Gilliam, C; Grassin-Delyle, S; Jarman, H; Lamy, E; McGuinness, W; Moss, P; Picetti, R; Pott, J; Prowse, D; Pynn, H; Roberts, I; Shakur-Still, H; Tai, N; Thayne, A; Urien, S, 2021)
"Tranexamic acid (TXA) is used as a hemostatic adjunct for hemorrhage control in the injured patient and reduces early preventable death."7.91Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism. ( Brown, JB; Kutcher, ME; Myers, SP; Neal, MD; Peitzman, AB; Rosengart, MR; Sperry, JL, 2019)
"To describe the use of tranexamic acid (TXA) in trauma care in England and Wales since the Clinical Randomization of an Antifibrinolytic in Significant Hemorrhage (CRASH-2) trial results were published in 2010."7.91Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study. ( Coats, TJ; Fragoso-Iñiguez, M; Roberts, I, 2019)
"We describe the case of a bleeding trauma patient who received tranexamic acid (TXA) during air transport who subsequently developed multiple intra-cardiac thrombi."7.88Left atrial thrombi following tranexamic acid in a bleeding trauma patient-A word of caution. ( Carroll, ND; Eastridge, BJ; Restrepo, CS; Stasik, CN, 2018)
"It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine, alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model."7.88Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. ( Feng, C; Gao, Y; Jin, H; Li, T; Liu, Y; Teng, Y, 2018)
"The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to assess the safety and impact on patient mortality of tranexamic acid (TXA) administration in cases of trauma-induced hemorrhagic shock."7.85Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study. ( Benson, P; Borger, R; Culhane, JT; Dong, F; Jabourian, A; Jabourian, N; Kissel, S; Kwong, E; Ludi, D; Mistry, J; Neeki, MM; O'Bosky, KR; Pennington, TW; Pitts, R; Powell, J; Schulz-Costello, K; Seiler, K; Sporer, K; Surrusco, MS; Toy, J; Vaezazizi, R; Van Stralen, D; Vara, R; Wong, D; Yoshida-McMath, C, 2017)
" Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy."7.79The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013)
"The early administration of tranexamic acid (TXA) to bleeding trauma patients reduces all-cause mortality without increasing the risk of vascular occlusive events."7.78Tranexamic acid: less bleeding and less thrombosis? ( Godier, A; Hunt, BJ; Roberts, I, 2012)
"In trauma patients with severe injury, 4 g intravenous bolus dosing of TXA has minimal immunomodulatory effects with respect to leukocyte phenotypes and circulating cytokine levels."6.94The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial. ( Baty, J; Bochicchio, GV; Bochicchio, K; Cap, AP; Coleoglou Centeno, AA; Fuchs, A; Horn, CB; Levy, JH; Meledeo, MA; Pusateri, AE; Reese, S; Schuerer, D; Shea, SM; Spinella, PC; Thomas, KA; Turnbull, IR, 2020)
"The trial included 20,127 trauma patients with, or at risk of, significant bleeding, within 8 hours of injury."6.78Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial. ( Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H, 2013)
"Compared to the CRASH-2 trial, adult trauma patients receiving TXA identified in our systematic review had a lower incidence of mortality at 28 or 30 days, but a higher incidence of in-hospital thrombotic events."6.61Mortality and Thrombosis in Injured Adults Receiving Tranexamic Acid in the Post-CRASH-2 Era. ( Benipal, S; Nishijima, DK; Santamarina, JL; Vo, L, 2019)
"Administration of TXA following traumatic injury was associated with MOF in the fibrinolysis shutdown and hyperfibrinolysis phenotypes and warrants continued evaluation."5.62Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury? ( Betzold, RD; Chow, JH; Fedeles, BT; Grissom, TE; Koerner, K; Kozar, RA; Morrison, JJ; Renner, C; Richards, JE; Scalea, TM; Schlee, CS; Trinh, AT, 2021)
"Tranexamic acid (TXA) has recently been used to treat bleeding in trauma by preventing plasmin generation to limit fibrinolysis."5.56Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography. ( Barrett, CD; Chandler, J; Ghasabyan, A; Moore, EE; Moore, HB; Vigneshwar, N; Yaffe, MB, 2020)
" Tranexamic acid (TXA) is a lysine analogue frequently used in the setting of significant trauma with hemorrhage."5.51Effect of age on the efficacy of tranexamic acid: An analysis of heterogeneity of treatment effect within the CRASH-2 dataset. ( Manoukian, MAC; Nishijima, DK; Tancredi, DJ, 2022)
"The TXA-loaded trauma-targeted nanovesicles (T-tNVs) were evaluated in vitro in rat blood, and then in vivo in a liver trauma model in rats."5.51Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model. ( Banerjee, A; Girish, A; Hickman, DA; Huang, S; Luc, N; Ma, Y; Miyazawa, K; Sekhon, UDS; Sen Gupta, A; Sun, M, 2019)
"Urgent treatment with tranexamic acid (TXA) reduces bleeding deaths but there is disagreement about which patients should be treated."5.22Effects of tranexamic acid treatment in severely and non-severely injured trauma patients. ( Ageron, FX; Roberts, I; Shakur-Still, H, 2022)
"To examine whether the effect of tranexamic acid on the risk of death and thrombotic events in patients with traumatic bleeding varies according to baseline risk of death."5.16Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. ( Brohi, K; Coats, T; Hunt, BJ; Lecky, F; Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H; Willett, K, 2012)
" 20,211 adult trauma patients with, or at risk of, significant bleeding were randomly assigned within 8 h of injury to either tranexamic acid (loading dose 1 g over 10 min followed by infusion of 1 g over 8 h) or placebo."5.15The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. ( Afolabi, A; Brohi, K; Coats, T; Dewan, Y; Gando, S; Guyatt, G; Hunt, BJ; Morales, C; Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H; Woolley, T, 2011)
"Tranexamic acid can reduce bleeding in patients undergoing elective surgery."5.14Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. ( Bautista, R; Caballero, J; Coats, T; Dewan, Y; El-Sayed, H; Gogichaishvili, T; Gupta, S; Herrera, J; Hunt, B; Iribhogbe, P; Izurieta, M; Khamis, H; Komolafe, E; Marrero, MA; Mejía-Mantilla, J; Miranda, J; Morales, C; Olaomi, O; Olldashi, F; Perel, P; Peto, R; Ramana, PV; Ravi, RR; Roberts, I; Shakur, H; Yutthakasemsunt, S, 2010)
"Tranexamic acid can reduce bleeding in patients undergoing elective surgery."5.14Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial. ( McDonald, AH; Strachan, GG; Williams, EW; Williams-Johnson, JA, 2010)
"Tranexamic acid (TXA) is an antifibrinolytic drug associated with improved survival among trauma patients with hemorrhage."5.12The impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis. ( Almuwallad, A; Cole, E; Davenport, R; Perkins, Z; Ross, J, 2021)
" Tranexamic acid (TXA) is one of the most commonly used and widely researched antifibrinolytic agents; its role in postpartum hemorrhage, menorrhagia, trauma-associated hemorrhage, and surgical bleeding has been well defined."5.05The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. ( Al-Samkari, H; Cai, J; DeLoughery, TG; Olson, S; Raghunathan, V; Ribkoff, J; Shatzel, JJ, 2020)
"Antifibrinolytic agent tranexamic acid (TXA) has a potential clinical benefit for in-hospital patients with severe bleeding but its effectiveness in pre-hospital settings remains unclear."4.98Efficacy of prehospital administration of tranexamic acid in trauma patients: A meta-analysis of the randomized controlled trials. ( Al-Thani, H; Asim, M; El-Menyar, A; Latifi, R; Sathian, B, 2018)
"Following results from the CRASH-2 trial, tranexamic acid (TXA) gained considerable interest for the treatment of hemorrhage in trauma patients."4.95Tranexamic Acid Update in Trauma. ( Bochicchio, GV; Ramirez, RJ; Spinella, PC, 2017)
"Tranexamic acid, an antifibrinolytic agent, reduces postoperative transfusion requirements but carries a poorly documented risk of thrombosis."4.89Trauma and severe bleeding. Tranexamic acid within one hour to reduce mortality. ( , 2013)
"Tranexamic acid safely reduces mortality in bleeding trauma patients without increasing the risk of adverse events."4.88Antifibrinolytic drugs for acute traumatic injury. ( Coats, T; Ker, K; Roberts, I; Shakur, H, 2012)
"In view of this efficacy and safety of this relatively cheap and simple drug, it may be recommended to put tranexamic acid in the first (maybe even prehospital) line of management of patients with severe traumatic hemorrhage."4.88Should antifibrinolytics be given in all patients with trauma? ( Levi, M, 2012)
" Based on current evidence the elements of an evolving strategy in transfusion management and bleeding control are exposed to use of tranexamic acid, combination and ratios of blood products, use of fluids and viscoelastic testing, etc."4.12Massive transfusion in trauma: an evolving paradigm. ( Bouzat, P; Gauss, T; Moyer, JD, 2022)
"Intravenous tranexamic acid (TXA) reduces bleeding deaths after injury and childbirth."4.02Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial. ( Davenport, R; Frimley, L; Gilliam, C; Grassin-Delyle, S; Jarman, H; Lamy, E; McGuinness, W; Moss, P; Picetti, R; Pott, J; Prowse, D; Pynn, H; Roberts, I; Shakur-Still, H; Tai, N; Thayne, A; Urien, S, 2021)
"To determine if there is a significant association between administration of tranexamic acid (TXA) in severely bleeding, injured patients, and venous thromboembolism (VTE), myocardial infarction (MI), or cerebrovascular accident (CVA)."4.02The incidence of venous thromboembolic events in trauma patients after tranexamic acid administration: an EAST multicenter study. ( Albertson, S; Allen, R; Bernard, A; Bugaev, N; Carrick, M; Carter, K; Chang, G; Cullinane, DC; Estroff, J; Grigorian, A; Hamrick, A; Harrell, K; Hazelton, JP; Jain, G; Jeyamurugan, K; Kovar, A; Kutcher, M; Lee, A; Luo-Owen, X; Mount, M; Nahmias, J; Pascual, J; Quattrone, M; Quispe, JC; Ratnasekera, A; Rivas, L; Rodriguez, C; Sarani, B; Selevany, M; Smith, SR; Spalding, C; Sparks, A; Tamburrini, D; Tororello, G; Turay, D; Urban, S; Vella, M; Warner, A; Weinberger, J; Wright, F, 2021)
"Tranexamic acid reduces surgical blood loss and reduces deaths from bleeding in trauma patients."4.02Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria. ( Ageron, FX; Coats, TJ; Darioli, V; Roberts, I, 2021)
"Tranexamic acid (TXA) has been shown to decrease mortality in adult trauma patients with or at significant risk of hemorrhage when administered within 3 h of injury."3.91Evaluation of tranexamic acid in trauma patients: A retrospective quantitative analysis. ( Burgess, S; Ng, M; Perrott, J, 2019)
"Tranexamic acid (TXA) is used as a hemostatic adjunct for hemorrhage control in the injured patient and reduces early preventable death."3.91Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism. ( Brown, JB; Kutcher, ME; Myers, SP; Neal, MD; Peitzman, AB; Rosengart, MR; Sperry, JL, 2019)
"To describe the use of tranexamic acid (TXA) in trauma care in England and Wales since the Clinical Randomization of an Antifibrinolytic in Significant Hemorrhage (CRASH-2) trial results were published in 2010."3.91Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study. ( Coats, TJ; Fragoso-Iñiguez, M; Roberts, I, 2019)
" Tranexamic acid (TXA) blocks both the tPA-dependent generation of plasmin on blood clots as well as active plasmin binding to polymerized fibrin, and is commonly administered for bleeding in trauma to limit fibrinolysis."3.91Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner. ( Barrett, CD; Chapman, MP; Kong, YW; Lim, D; Moore, EE; Moore, HB; Sriram, G; Yaffe, MB, 2019)
" We are planning a multicenter, randomized clinical trial evaluating tranexamic acid in children with hemorrhage."3.91Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process. ( Galante, JM; Hewes, HA; Kuppermann, N; Meyers, SR; Nishijima, DK; Nuno, MA; Stanley, RM; Stephenson, JT; Thompson, KM; Trappey, AF, 2019)
" Tranexamic acid administration was an independent risk factor for venous thromboembolism (odds ratio, 2."3.88Evaluation of Military Use of Tranexamic Acid and Associated Thromboembolic Events. ( Bradley, MJ; Elster, EA; Johnston, LR; Rodriguez, CJ, 2018)
"We describe the case of a bleeding trauma patient who received tranexamic acid (TXA) during air transport who subsequently developed multiple intra-cardiac thrombi."3.88Left atrial thrombi following tranexamic acid in a bleeding trauma patient-A word of caution. ( Carroll, ND; Eastridge, BJ; Restrepo, CS; Stasik, CN, 2018)
"It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine, alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model."3.88Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. ( Feng, C; Gao, Y; Jin, H; Li, T; Liu, Y; Teng, Y, 2018)
"Tranexamic acid was associated with increased 6-hour survival but does not improve long-term outcomes in severely injured trauma patients with hemorrhage who develop hyperfibrinolysis."3.88Severely injured trauma patients with admission hyperfibrinolysis: Is there a role of tranexamic acid? Findings from the PROPPR trial. ( Bulger, EM; Holcomb, JB; Jehan, F; Joseph, B; Khan, M; OʼKeeffe, T; Schreiber, MA; Wade, CE, 2018)
"The present study aimed to examine the association between tranexamic acid use and adverse effects (seizures, thromboembolism, and renal dysfunction) in a pediatric trauma population using a national inpatient database in Japan."3.88Safety of Tranexamic Acid During Pediatric Trauma: A Nationwide Database Study. ( Maeda, T; Matsui, H; Michihata, N; Miyata, S; Ohnishi, Y; Sasabuchi, Y; Yasunaga, H, 2018)
" The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to evaluate the safety and efficacy of tranexamic acid (TXA) use in the civilian prehospital setting in cases of traumatic hemorrhagic shock."3.88Tranexamic Acid in Civilian Trauma Care in the California Prehospital Antifibrinolytic Therapy Study. ( Borger, R; Burgett-Moreno, M; Dong, F; Jabourian, A; Kissel, S; Kwong, E; Lee, T; Ludi, D; Luo-Owen, X; Mousselli, M; Neeki, MM; Niknafs, N; O'Bosky, KR; Pennington, T; Powell, J; Rabiei, M; Sporer, K; Toy, J; Vaezazizi, R; Vara, R; Wong, D, 2018)
"The use of TXA in the treatment of traumatic bleeding has the potential to prevent many premature deaths every year."3.86Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial. ( Edwards, P; Ker, K; Kiriya, J; Perel, P; Roberts, I; Shakur, H, 2012)
"The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to assess the safety and impact on patient mortality of tranexamic acid (TXA) administration in cases of trauma-induced hemorrhagic shock."3.85Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study. ( Benson, P; Borger, R; Culhane, JT; Dong, F; Jabourian, A; Jabourian, N; Kissel, S; Kwong, E; Ludi, D; Mistry, J; Neeki, MM; O'Bosky, KR; Pennington, TW; Pitts, R; Powell, J; Schulz-Costello, K; Seiler, K; Sporer, K; Surrusco, MS; Toy, J; Vaezazizi, R; Van Stralen, D; Vara, R; Wong, D; Yoshida-McMath, C, 2017)
" The aim of this study was to investigate the combined effect of transfusion ratios, tranexamic acid and products containing fibrinogen on the outcome of injured patients with bleeding."3.85Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy. ( Baksaas-Aasen, K; Balvers, K; Brohi, K; Eaglestone, S; Gaarder, C; Goslings, JC; Johansson, PI; Juffermans, NP; Maegele, M; Ostrowski, SR; Stanworth, S; Stensballe, J; van Dieren, S, 2017)
" The current European Management of Major Bleeding and Coagulopathy Following Trauma guidelines, published in 2013, recommend that tranexamic acid (TXA) be administered as early as possible to inhibit hyperfibrinolysis (grade of recommendation (GoR 1A))."3.85[Tranexamic acid in the German emergency medical service : A national survey]. ( Balzer, F; Casu, S; Greb, I; Henkelmann, A; Kaufner, L; von Heymann, C; Weber, CF; Zacharowski, K; Zickenrott, V, 2017)
"Based upon the results of CRASH-2, early administration of antifibrinolytic tranexamic acid (TXA) is recommended in bleeding trauma patients or trauma patients presumed to bleed."3.83[Uncritical use of tranexamic acid in trauma patients : Do no further harm!] ( Maegele, M, 2016)
" The CRASH-2 trial demonstrated that early administration of tranexamic acid, ideally within 3 hours, can reduce mortality from trauma-associated bleeding by up to 32%."3.81Time since injury is the major factor in preventing tranexamic acid use in the trauma setting: An observational cohort study from a major trauma centre in a middle-income country. ( Chowdhury, S; Edu, S; Navsaria, PH; Nicol, AJ; Thurston, B, 2015)
"Accumulating evidence established the benefit of tranexamic acid (TXA) for traumatic bleeding in the hospital setting."3.80Tranexamic acid at the point of injury: the Israeli combined civilian and military experience. ( Abramovich, A; Benov, A; Gendler, S; Glassberg, E; Nadler, R; Strugo, R, 2014)
" Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy."3.79The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013)
" Reducing injection pain of local anesthetics, reducing irradiation by using alternative diagnostic tools in appendicitis suspicion, and identification of trauma patients who benefit from tranexamic acid administration are other illustrations of the efforts to improve efficacy, safety and comfort in the management of emergency patients."3.78[Emergency medicine: updates 2011]. ( Carron, PN; Dami, F; Grosgurin, O; Marti, C; Rutschmann, O; Rutz, P, 2012)
"The early administration of tranexamic acid (TXA) to bleeding trauma patients reduces all-cause mortality without increasing the risk of vascular occlusive events."3.78Tranexamic acid: less bleeding and less thrombosis? ( Godier, A; Hunt, BJ; Roberts, I, 2012)
" This series of studies tested whether these drugs (aprotinin, desmopressin, tranexamic acid, epsilon-aminocaproic acid) could reduce bleeding due to traumatic injuries in two models of uncontrolled hemorrhage in rats."3.73Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage. ( Cortez, DS; Dick, EJ; Pusateri, AE; Ryan, KL, 2006)
"We randomly assigned adults with major trauma who were at risk for trauma-induced coagulopathy to receive tranexamic acid (administered intravenously as a bolus dose of 1 g before hospital admission, followed by a 1-g infusion over a period of 8 hours after arrival at the hospital) or matched placebo."3.30Prehospital Tranexamic Acid for Severe Trauma. ( Bernard, SA; Burns, B; Cameron, PA; Dicker, B; Forbes, AB; Gantner, DC; Gruen, RL; Hurford, S; Maegele, M; Martin, CA; Mazur, SM; McArthur, CJ; Medcalf, RL; Mitra, B; Murray, LJ; Myles, PS; Ng, SJ; Pitt, V; Rashford, S; Reade, MC; Swain, AH; Trapani, T; Young, PJ, 2023)
" Individual conclusions regarding optimal dosing of TXA can be made within each injury group."3.01The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children. ( Casper, TC; Dean, JM; Kuppermann, N; Lewis, RJ; McGlothlin, A; Nishijima, DK; VanBuren, JM, 2021)
"Hemorrhage and trauma-induced coagulopathy cause significant morbidity and mortality in trauma patients."3.01Alternative blood products in trauma. ( Jan, KM; Mohapatra, S; Moon, TS, 2023)
"Hemorrhage is a leading cause of death after trauma and childbirth."2.94Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials. ( Bates, I; Bello, A; Chaudhri, R; Kolin, DA; Roberts, I; Shakur-Still, H, 2020)
"In trauma patients with severe injury, 4 g intravenous bolus dosing of TXA has minimal immunomodulatory effects with respect to leukocyte phenotypes and circulating cytokine levels."2.94The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial. ( Baty, J; Bochicchio, GV; Bochicchio, K; Cap, AP; Coleoglou Centeno, AA; Fuchs, A; Horn, CB; Levy, JH; Meledeo, MA; Pusateri, AE; Reese, S; Schuerer, D; Shea, SM; Spinella, PC; Thomas, KA; Turnbull, IR, 2020)
"Bleeding is an important cause of death in trauma victims."2.90Introduction of a standardised protocol, including systematic use of tranexamic acid, for management of severe adult trauma patients in a low-resource setting: the MSF experience from Port-au-Prince, Haiti. ( Benedetti, G; Edema, N; Jachetti, A; Massénat, RB; Trelles, M; Van Den Bergh, R; Woolley, SC, 2019)
"Future trauma trials that evaluate tranexamic acid use should also consider functional status as an important outcome."2.90The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial. ( Kuppermann, N; Nishijima, DK; Roberts, I; Tancredi, DJ; VanBuren, JM, 2019)
"The evidence gap in mature civilian trauma systems is limiting the widespread use of TXA and its potential benefits on survival."2.80Tranexamic acid use in severely injured civilian patients and the effects on outcomes: a prospective cohort study. ( Brohi, K; Cole, E; Davenport, R; Willett, K, 2015)
"The trial included 20,127 trauma patients with significant bleeding from 274 hospitals in 40 countries."2.79Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study. ( Altman, DG; Clayton, T; Croft, P; Douglas, I; Hemingway, H; Hingorani, A; Morley, KI; Perel, P; Riley, R; Roberts, I; Timmis, A; Van der Windt, D, 2014)
"The trial included 20,127 trauma patients with, or at risk of, significant bleeding, within 8 hours of injury."2.78Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial. ( Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H, 2013)
"Trauma is a major source of morbidity and mortality for children worldwide; life-threatening hemorrhage is a primary cause of preventable death."2.72Hemostatic Resuscitation in Children. ( Leeper, C; Ramos-Jimenez, RG, 2021)
"Nine studies, comprising of 1218 trauma patients and 1432 device insertions, were included."2.72Intraosseous access in the resuscitation of trauma patients: a literature review. ( De'Ath, HD; Perkins, Z; Tyler, JA, 2021)
"A quality assurance review of eligible trauma patients across the province was performed using a convenience sample."2.72Assessing the clinical utilization of tranexamic acid by paramedics for patients with major trauma (ACUTE). ( Acker, J; Jenneson, S; Mabasa, VH; Su, G; Tallon, JM; Wan, W; Wong, D, 2021)
"Tranexamic acid (TXA) is an antifibrinolytic agent used to prevent traumatic exsanguination."2.66The Use of Tranexamic Acid (TXA) for the Management of Hemorrhage in Trauma Patients in the Prehospital Environment: Literature Review and Descriptive Analysis of Principal Themes. ( Jesulola, E; Morris, D; Stansfield, R, 2020)
"Special trauma populations at particularly high risk are also reviewed, including the geriatric population, as well as unstable pelvic fractures, which are each at increased risk for poor outcomes, and deserve special attention."2.66Limiting Blood Loss in Orthopaedic Trauma: Strategies and Effects. ( Leighton, JL; Schneider, P; You, D, 2020)
"Transfusion therapy in hemorrhaging trauma patients is associated with the development of thromboembolic events."2.66The impact of blood product ratio and procoagulant therapy on the development of thromboembolic events in severely injured hemorrhaging trauma patients. ( Goslings, JC; Juffermans, NP; Schalkers, DV; Wirtz, MR, 2020)
"Acute blood loss in trauma requires quick identification and action to restore circulating volume and save the patient."2.66Massive transfusion protocol in adult trauma population. ( Boneva, D; Elkbuli, A; McKenney, M; Meneses, E, 2020)
"TXA concentrations of 10-15 mg/l may be suitable targets for pharmacokinetic studies, although TXA concentrations above 5 mg/l may also be effective."2.61What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies. ( Medcalf, RL; Picetti, R; Roberts, I; Shakur-Still, H; Standing, JF, 2019)
" Recent data on TXA's use in spine surgery suggest that TXA remains both efficacious and safe, although the ideal dosing and timing of administration is still a point of disagreement."2.61The Use of Tranexamic Acid to Reduce Surgical Blood Loss: A Review Basic Science, Subspecialty Studies, and The Evolution of Use in Spine Deformity Surgery. ( Kark, J; Slattery, C; Verma, K; Wagner, T, 2019)
"The improved understanding of trauma-induced coagulopathy in adults has led to an evolution in the strategies of damage-control resuscitation."2.61Pediatric trauma-related coagulopathy: Balanced resuscitation, goal-directed therapy and viscoelastic assays. ( Drucker, NA; Newton, C; Wang, SK, 2019)
"Compared to the CRASH-2 trial, adult trauma patients receiving TXA identified in our systematic review had a lower incidence of mortality at 28 or 30 days, but a higher incidence of in-hospital thrombotic events."2.61Mortality and Thrombosis in Injured Adults Receiving Tranexamic Acid in the Post-CRASH-2 Era. ( Benipal, S; Nishijima, DK; Santamarina, JL; Vo, L, 2019)
"Uncontrolled hemorrhage and subsequent trauma-induced coagulopathy (TIC) are still the principle causes for preventable death after trauma and early detection and aggressive management have been associated with reduced mortality."2.55Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy. ( Gu, ZT; Huang, QB; Maegele, M; Yang, H, 2017)
"In patients with orthopaedic trauma, TXA reduces the risk of blood transfusion, reduces perioperative blood loss, and has no significant effect on the risk of symptomatic thromboembolic events."2.55Tranexamic Acid in Orthopaedic Trauma Surgery: A Meta-Analysis. ( Boone, MD; Gausden, EB; Lorich, DG; OʼGara, B; Qudsi, R; Ruzbarsky, JJ, 2017)
"Tranexamic acid has gained recent interest in orthopedics and trauma surgery because of its demonstrated benefit in several clinical trials."2.53Application of Tranexamic Acid in Trauma and Orthopedic Surgery. ( Haydel, C; Jennings, JD; Solarz, MK, 2016)
"Paediatric trauma is the leading cause of mortality in children."2.53Paediatric trauma resuscitation: an update. ( Giannoudis, PV; Tosounidis, TH, 2016)
"Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions."2.53[Anti DIC therapy]. ( Sakamoto, Y; Yahata, M, 2016)
"The use of tranexamic acid in trauma was supported by "high" quality evidence according to the GRADE classification but was downgraded to "moderate" for external validity issues."2.53Blood Component Therapy and Coagulopathy in Trauma: A Systematic Review of the Literature from the Trauma Update Group. ( Chiara, O; Chieregato, A; Coniglio, C; Cortegiani, A; De Blasio, E; Fossi, F; Gianesello, L; Gordini, G; Grossi, S; Mengoli, F; Orzalesi, V; Pellegrini, C; Poole, D; Russo, E; Volpi, A, 2016)
"In most trauma centres, coagulation therapy is established with transfusion of high volumes of fresh frozen plasma."2.52Management of traumatic haemorrhage--the European perspective. ( Schlimp, CJ; Schöchl, H; Voelckel, W, 2015)
" Additionally, risk of thromboembolism, dosing regimens, and timing of dosing are assessed."2.52Tranexamic acid: from trauma to routine perioperative use. ( Pittet, JF; Sikorski, RA; Simmons, J, 2015)
"Uncontrolled bleeding is an important cause of death in trauma victims."2.52Antifibrinolytic drugs for acute traumatic injury. ( Coats, TJ; Ker, K; Roberts, I; Shakur, H, 2015)
"Tranexamic acid (TXA) has recently been shown to reduce mortality in trauma patients when administered upon hospital admission, and available data suggest that early dosing confers maximum benefit."2.52Tranexamic acid as part of remote damage-control resuscitation in the prehospital setting: A critical appraisal of the medical literature and available alternatives. ( Ausset, S; Cap, AP; Glassberg, E; Hoffmann, C; Nadler, R; Plang, S; Sailliol, A; Sunde, G, 2015)
"Herein, we explore the underpinnings of trauma associated coagulopathy, the basic science behind the role of fibrinogen in acute traumatic coagulopathy, and the rationale behind and the data derived from management of hypofibrinogenemia as well as hyperfibrinolysis."2.50Role of fibrinogen in massive injury. ( Kaplan, LJ; Maung, AA, 2014)
"The coagulopathy induced by trauma is independently associated with mortality, increased transfusion requirements, multiple organ dysfunction, infections, increased intensive care unit (ICU) length of stay, and costs."2.50A systematic review of antifibrinolytics and massive injury. ( Faraoni, D; Van Der Linden, P, 2014)
"Fibrinogen depletes early after severe trauma; therefore, it seems to be reasonable to maintain plasma fibrinogen as early as possible."2.50Tranexamic acid, fibrinogen concentrate, and prothrombin complex concentrate: data to support prehospital use? ( Maegele, M; Schlimp, CJ; Schöchl, H, 2014)
"Bleeding in trauma carries a high mortality and is increased in case of coagulopathy."2.50Viscoelastic guidance of resuscitation. ( Johansson, PI; Ostrowski, SR; Stensballe, J, 2014)
"Bleeding and coagulopathy after trauma increases mortality in both adults and children."2.50Tranexamic acid in pediatric trauma: why not? ( Ackery, AD; Beno, S; Callum, J; Rizoli, S, 2014)
"Diagnosis and treatment of trauma-induced coagulopathy (TIC) presents a challenge for trauma care providers."2.49Potential value of pharmacological protocols in trauma. ( Schlimp, CJ; Schöchl, H; Voelckel, W, 2013)
"Future treatment of trauma-induced coagulopathy may be based on systemic antifibrinolytics, local haemostatics and individualized point-of-care-guided rational use of coagulation factor concentrates such as fibrinogen, prothrombin complex concentrate, recombinant factor VIIa and factor XIII."2.48Emerging treatment strategies for trauma-induced coagulopathy. ( Fries, D; Sorensen, B, 2012)
"The management of trauma patients has matured significantly since a systematic approach to trauma care was introduced nearly a half century ago."2.48Review article: update in trauma anesthesiology: perioperative resuscitation management. ( Tobin, JM; Varon, AJ, 2012)
"Current evidence in trauma resuscitation indicates a potential role for coagulation factor concentrates and other haemostatic agents in correcting trauma-induced coagulopathy."2.48Coagulation management. ( Grottke, O, 2012)
"Uncontrolled bleeding is an important cause of death in trauma victims."2.47Antifibrinolytic drugs for acute traumatic injury. ( Coats, T; Ker, K; Roberts, I; Shakur, H, 2011)
"Tranexamic acid (TXA) is an antifibrinolytic that inhibits both plasminogen activation and plasmin activity, thus preventing clot break-down rather than promoting new clot formation."2.47Tranexamic acid for trauma patients: a critical review of the literature. ( Aden, J; Baer, DG; Blackbourne, LH; Cap, AP; Orman, JA; Ryan, K, 2011)
"Hemorrhage is the leading cause of preventable death after injury."1.91Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage. ( Brown, JB; Claridge, JA; Daley, BJ; Deeb, AP; Eastridge, BJ; Guyette, FX; Harbrecht, BG; Joseph, B; Miller, RS; Nirula, R; Phelan, HA; Sperry, JL; Vercruysse, GA, 2023)
"Pediatric trauma patients less than 18 years old."1.91Prehospital Tranexamic Acid Administration in Pediatric Trauma Patients: A Propensity-Matched Analysis of the Israeli Defense Forces Registry. ( Ahimor, A; Almog, O; Avital, G; Benov, A; Gelikas, S; Gendler, S; Glassberg, E; Lipsky, AM; Mozer Glassberg, Y; Nadler, R; Radomislensky, I; Talmy, T; Yazer, MH, 2023)
"Second, we examined data from the Trauma and Audit Research Network (TARN) to explore sex differences in the receipt of TXA."1.72Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2 and CRASH-3) trials and UK trauma registry (Trauma and Audit Research Network) data. ( Ageron, FX; Brenner, A; Nutbeam, T; Roberts, I; Shakur-Still, H; Weekes, L, 2022)
" The median dosage was 16 mg/kg (13-19 mg/kg)."1.72Prehospital Tranexamic Acid in Major Pediatric Trauma Within a Physician-Led Emergency Medical Services System: A Multicenter Retrospective Study. ( Benhamed, A; Bouchut, JC; Claustre, C; Courtil-Teyssedre, S; David, JS; El Khoury, C; Fraticelli, L; Gossiome, A; Jacquet, L; Javouhey, E; Mercier, E; Taverna, XJ; Tazarourte, K, 2022)
"Military neck injuries are a significant cause of substantial disability and result in incompatibility with combat duties in previously healthy soldiers."1.62Neck injuries - israel defense forces 20 years' experience. ( Abuhasira, S; Benov, A; Chen, J; Glick, Y; Mizrachi, A; Nadler, R; Radomislensky, I; Tsur, AM; Tsur, N, 2021)
"Ninety-five patients received TXA for traumatic injuries, 42."1.62Unjustified Administration in Liberal Use of Tranexamic Acid in Trauma Resuscitation. ( Adams, CA; Jikaria, N; Kheirbek, T; Lueckel, SN; Martin, TJ; Monaghan, SF; Murray, B; Stephen, AH, 2021)
"Administration of TXA following traumatic injury was associated with MOF in the fibrinolysis shutdown and hyperfibrinolysis phenotypes and warrants continued evaluation."1.62Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury? ( Betzold, RD; Chow, JH; Fedeles, BT; Grissom, TE; Koerner, K; Kozar, RA; Morrison, JJ; Renner, C; Richards, JE; Scalea, TM; Schlee, CS; Trinh, AT, 2021)
"During the period studied, 53 trauma patients requiring activation of the MTP were identified."1.62Use of tranexamic acid in trauma patients requiring massive transfusion protocol activation: a reassessment of prescribing behaviours in a major trauma centre in New Zealand. ( Chapman, NG; Nicholas, ERV, 2021)
"Tranexamic acid (TXA) has shown to be beneficial in patients in hemorrhagic shock, although widespread adoption might result in incorrect TXA administration leading to increased morbidity and mortality."1.62Does Liberal Prehospital and In-Hospital Tranexamic Acid Influence Outcome in Severely Injured Patients? A Prospective Cohort Study. ( Leenen, LPH; van Wessem, KJP, 2021)
"An academic level 1 trauma centre in the Lyon Region, from March 2011 to December 2016."1.56Fibrinolytic shutdown diagnosed with rotational thromboelastometry represents a moderate form of coagulopathy associated with transfusion requirement and mortality: A retrospective analysis. ( Bouzat, P; David, JS; Geay-Baillat, AM; Inaba, K; Incagnoli, P; Lambert, A; Maegele, M; Taverna, XJ, 2020)
"After major trauma, there seems to be an early 'antifibrinolytic gap' with the natural antifibrinolytic system lagging several hours behind the natural profibrinolytics."1.56Biological mechanisms and individual variation in fibrinolysis after major trauma. ( Coats, TJ; Morsy, M, 2020)
" Secondary outcomes included total blood products transfused, hospital length of stay (LOS), intensive care unit LOS, and adverse events."1.56Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation. ( Borger, R; Chandwani, D; Comunale, ME; Dong, F; Inaba, K; Lowe, A; Neeki, MM; Powell, J; Quispe, J; Rabiei, M; Salameh, J; Toy, J; Vara, R; Wong, D, 2020)
"Tranexamic acid (TXA) has recently been used to treat bleeding in trauma by preventing plasmin generation to limit fibrinolysis."1.56Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography. ( Barrett, CD; Chandler, J; Ghasabyan, A; Moore, EE; Moore, HB; Vigneshwar, N; Yaffe, MB, 2020)
"Tranexamic acid has been proven to reduce all causes of mortality and mortality due to bleeding."1.51Administration of tranexamic acid for victims of severe trauma within pre-hospital care ambulance services (PHCAS) in Malaysia. ( Ahmad Ibrahim, KB; Ahmad Tajuddin, MN; Aik Howe, T; Anandakumar, K; Fatahul Laham, M; Fitzgerald, M; Kiat Kee, G; Mathew, J; Md Saed, M; Mohd Amin, M; Mohd Idzwan, Z; Mohd Khairizam, MY; Nurul Azlean, N; Ridzuan, MI; Sabariah Faizah, J; Shah Jahan, MY; Shamila, MA, 2019)
"Hemorrhage is the leading cause of potentially survivable deaths in combat."1.51An Analysis of Adherence to Tactical Combat Casualty Care Guidelines for the Administration of Tranexamic Acid. ( April, MD; Carius, BM; Fisher, AD; Maddry, JK; Naylor, JF; Schauer, SG, 2019)
"Adult major trauma patients with, or at risk of, active bleeding who were managed according to the MTP during the years 2011-2012, or the ECS protocol during the years 2013-2014 and were considered at risk of multiple transfusions, were enrolled."1.51Early coagulation support protocol: A valid approach in real-life management of major trauma patients. Results from two Italian centres. ( Antonelli, M; Barelli, R; Bianchi, M; Bocci, MG; Caricato, A; Cingolani, E; Cutuli, SL; De Candia, E; De Pascale, G; Dell'Anna, AM; Fiore, V; Grieco, DL; Maresca, M; Mercurio, G; Nardi, G; Palma, A; Rondinelli, MB; Tersali, A; Veronesi, G, 2019)
"Tranexamic acid (TXA) has been shown to reduce mortality in the treatment of traumatic hemorrhage."1.51Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury. ( Boudreau, RM; Day, GM; Deshpande, KK; Goodman, MD; Harger, N; Hinckley, WR; Makley, AT; Pritts, TA, 2019)
"We prospectively recruited hemorrhaging trauma patients in six level-1 trauma centres in Europe."1.51Towards patient-specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry. ( Baksaas-Aasen, K; Balvers, K; Brohi, K; Gaarder, C; Goslings, JC; Johansson, PI; Juffermans, NP; Maegele, M; Naess, PA; Stanworth, S; Stensballe, J; van Dieren, S; Wirtz, MR, 2019)
"The TXA-loaded trauma-targeted nanovesicles (T-tNVs) were evaluated in vitro in rat blood, and then in vivo in a liver trauma model in rats."1.51Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model. ( Banerjee, A; Girish, A; Hickman, DA; Huang, S; Luc, N; Ma, Y; Miyazawa, K; Sekhon, UDS; Sen Gupta, A; Sun, M, 2019)
"Objective Multidisciplinary trauma teams are the standard of care in the USA, but staffing differences and lack of advanced trauma life support training hinder replication of this system in Chinese hospitals."1.48Effect of team training on efficiency of trauma care in a Chinese hospital. ( Cai, X; Hong, Y, 2018)
"MODS was compared between groups according to biomarker dynamics: persistently abnormal; abnormal to normal; and persistently normal."1.48Endotheliopathy of Trauma is an on-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational Study. ( Belli, A; Bishop, J; Davies, DJ; Harrison, P; Hazeldine, J; Lord, JM; Midwinter, MJ; Naumann, DN, 2018)
"Tranexamic acid was administered at a median (IQR [range]) time of 43 (30-55 [5-135]) min after trauma."1.48Optimisation of the dosage of tranexamic acid in trauma patients with population pharmacokinetic analysis. ( Albrecht, R; Grassin-Delyle, S; Mueller, S; Spahn, DR; Stein, P; Theusinger, OM; Urien, S, 2018)
"Tranexamic acid (TXA) use in severe trauma remains controversial notably because of concerns of the applicability of the CRASH-2 study findings in mature trauma systems."1.48Tranexamic acid in severe trauma patients managed in a mature trauma care system. ( Abback, P; Ausset, S; Boutonnet, M; Cap, AP; Follin, A; Harrois, A; Imbert, N; Le Saché, F; Trichereau, J, 2018)
"The onset of acute traumatic coagulopathy in trauma patients exacerbates hemorrhaging and dramatically increases mortality."1.48Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy. ( Brummel-Ziedins, K; Buoni, M; Cohen, M; Orfeo, T; Petzold, L; Wu, S; Wu, TB, 2018)
"During the period studied, 27 adult trauma patients who required activation of the MTP were identified."1.48Use of tranexamic acid in trauma patients requiring massive transfusion protocol activation: an audit in a major trauma centre in New Zealand. ( Chapman, N, 2018)
"We hypothesize that trauma patients who present to the hospital with physiological levels of fibrinolysis will have increased mortality if they receive TXA."1.46Tranexamic acid is associated with increased mortality in patients with physiological fibrinolysis. ( Einersen, PM; Huebner, BR; Moore, EE; Moore, HB; Nunns, GR; Sauaia, A; Silliman, CC; Stettler, GR, 2017)
"Tranexamic acid (TXA) has been previously reported to have a mortality benefit in civilian and combat-related trauma, and was thus added to the Joint Theater Trauma System Damage Control Resuscitation Clinical Practice Guideline."1.46Military use of tranexamic acid in combat trauma: Does it matter? ( Bailey, JA; Cap, AP; Gross, KR; Howard, JT; Stockinger, ZT, 2017)
"Tranexamic acid (TXA) has been shown to reduce mortality from severe haemorrhage."1.43Tranexamic acid in life-threatening military injury and the associated risk of infective complications. ( Carson, ML; Lewis, CJ; Li, P; Murray, CK; Ross, JD; Stewart, L; Tribble, DR; Weintrob, AC, 2016)
" Additional work is needed to identify appropriate indications for TXA and provide dosage guidelines among children with a variety of conditions, including trauma."1.43Tranexamic Acid Use in United States Children's Hospitals. ( Faraoni, D; Galante, J; Goobie, SM; Holmes, JF; Kuppermann, N; Lee, L; Monuteaux, MC; Nishijima, DK, 2016)
"Primarily admitted trauma patients (2012 until 2014) who were treated with TXA during the prehospital phase were matched with patients who had not received prehospital TXA, applying propensity score-based matching."1.43Prehospital administration of tranexamic acid in trauma patients. ( Böhmer, AB; Bouillon, B; Gäßler, M; Lefering, R; Ruppert, M; Wafaisade, A, 2016)
"Tranexamic acid was considered in MTP trauma patients who arrived at the medical center within 8 hours of traumatic injury, were 15 years of age or older, and weighed at least 40 kg."1.42Addition of tranexamic acid to a traumatic injury massive transfusion protocol. ( Burke, PA; Farrell, NM; Huiras, P; Wing, HA, 2015)
" Standard adult dosing of TXA was used in all patients."1.40Tranexamic acid administration to pediatric trauma patients in a combat setting: the pediatric trauma and tranexamic acid study (PED-TRAX). ( Eckert, MJ; Izenberg, S; Martin, MJ; Nelson, DW; Tyner, SD; Wertin, TM, 2014)
"The aim of the study was to create a trauma coagulopathy model (TCM) with a hyperfibrinolysis thrombelastography (TEG) pattern similar to injured patients and test the effects of different resuscitation fluids and antifibrinolytics on fibrinolysis."1.39Influence of resuscitation fluids, fresh frozen plasma and antifibrinolytics on fibrinolysis in a thrombelastography-based, in-vitro, whole-blood model. ( Cotton, BA; Holcomb, JB; Kostousov, V; Matijevic, N; Wade, CE; Wang, YW, 2013)
"and U."1.39Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study. ( Dubose, JJ; Jansen, JO; Midwinter, MJ; Morrison, JJ; Rasmussen, TE; Ross, JD, 2013)
"It is present in 2-8% of trauma patients and associated with shock and increased mortality."1.37[Hyperfibrinolysis as the cause of haemorrhage and increased mortality in trauma patients]. ( Afshari, A; Johansson, PI; Stensballe, J; Wikkelsø, AJ, 2011)

Research

Studies (216)

TimeframeStudies, this research(%)All Research%
pre-19902 (0.93)18.7374
1990's0 (0.00)18.2507
2000's7 (3.24)29.6817
2010's153 (70.83)24.3611
2020's54 (25.00)2.80

Authors

AuthorsStudies
Gauss, T1
Moyer, JD1
Bouzat, P2
Ramos-Jimenez, RG1
Leeper, C1
Rossetto, A1
Vulliamy, P2
Lee, KM1
Brohi, K6
Davenport, R4
VanBuren, JM2
Casper, TC1
Nishijima, DK7
Kuppermann, N4
Lewis, RJ1
Dean, JM1
McGlothlin, A1
Manoukian, MAC1
Tancredi, DJ2
Roberts, I30
Shakur-Still, H7
Nutbeam, T1
Weekes, L1
Brenner, A1
Ageron, FX4
Gossiome, A1
Claustre, C1
Fraticelli, L1
Jacquet, L1
Bouchut, JC1
Javouhey, E1
Courtil-Teyssedre, S1
Taverna, XJ2
David, JS4
Mercier, E1
Tazarourte, K1
El Khoury, C1
Benhamed, A1
Borgman, MA1
Cazes, N1
Balaz, PA1
Renard, A1
Boutillier du Retail, C1
Deeb, AP1
Guyette, FX1
Daley, BJ1
Miller, RS1
Harbrecht, BG1
Claridge, JA1
Phelan, HA1
Eastridge, BJ2
Joseph, B2
Nirula, R1
Vercruysse, GA1
Sperry, JL2
Brown, JB2
Jan, KM1
Mohapatra, S1
Moon, TS1
Gendler, S2
Gelikas, S1
Talmy, T1
Lipsky, AM1
Avital, G1
Nadler, R5
Radomislensky, I2
Ahimor, A1
Glassberg, E4
Mozer Glassberg, Y1
Almog, O1
Yazer, MH2
Benov, A4
Gruen, RL7
Mitra, B4
Bernard, SA1
McArthur, CJ1
Burns, B1
Gantner, DC1
Maegele, M7
Cameron, PA2
Dicker, B1
Forbes, AB1
Hurford, S1
Martin, CA1
Mazur, SM1
Medcalf, RL4
Murray, LJ1
Myles, PS1
Ng, SJ1
Pitt, V2
Rashford, S1
Reade, MC5
Swain, AH1
Trapani, T1
Young, PJ1
Shah Jahan, MY1
Shamila, MA1
Nurul Azlean, N1
Mohd Amin, M1
Anandakumar, K1
Ahmad Ibrahim, KB1
Ahmad Tajuddin, MN1
Aik Howe, T1
Md Saed, M1
Fatahul Laham, M1
Ridzuan, MI1
Mohd Idzwan, Z1
Mohd Khairizam, MY1
Mathew, J1
Fitzgerald, M2
Sabariah Faizah, J1
Kiat Kee, G1
Walsh, K1
O'Keeffe, F1
Moore, HB9
Moore, BA1
Sauaia, A6
Moore, EE10
Lambert, A1
Incagnoli, P1
Geay-Baillat, AM1
Inaba, K4
Jachetti, A1
Massénat, RB1
Edema, N1
Woolley, SC1
Benedetti, G1
Van Den Bergh, R1
Trelles, M1
Fisher, AD1
Carius, BM1
April, MD1
Naylor, JF1
Maddry, JK1
Schauer, SG1
Bocci, MG1
Nardi, G1
Veronesi, G1
Rondinelli, MB1
Palma, A1
Fiore, V1
De Candia, E1
Bianchi, M1
Maresca, M1
Barelli, R1
Tersali, A1
Dell'Anna, AM1
De Pascale, G1
Cutuli, SL1
Mercurio, G1
Caricato, A1
Grieco, DL1
Antonelli, M1
Cingolani, E1
Cai, J1
Ribkoff, J1
Olson, S1
Raghunathan, V1
Al-Samkari, H1
DeLoughery, TG1
Shatzel, JJ1
Hu, M1
Liu, ZB1
Bi, G1
Coats, TJ4
Morsy, M1
Stansfield, R1
Morris, D1
Jesulola, E1
Tyler, JA1
Perkins, Z2
De'Ath, HD1
Neeki, MM3
Dong, F3
Toy, J3
Salameh, J1
Rabiei, M2
Powell, J4
Vara, R3
Wong, D4
Comunale, ME1
Lowe, A1
Chandwani, D1
Quispe, J1
Borger, R3
Draxler, DF1
Barrett, CD4
Yaffe, MB4
Briggs, GD1
Balogh, ZJ1
Walsh, M2
Grisoli, A1
Zackariya, N1
Thomas, AV1
Sualeh, A1
Wu, TB2
Orfeo, T2
Sumislawski, JJ1
Cohen, MJ5
Petzold, LR1
Leighton, JL1
You, D1
Schneider, P1
Tsur, AM2
Shinar, E1
Moshe, T1
Epstein, D1
Chen, J2
Kolin, DA1
Bello, A1
Chaudhri, R1
Bates, I1
Wirtz, MR2
Schalkers, DV1
Goslings, JC3
Juffermans, NP3
Vigneshwar, N2
Ghasabyan, A1
Chandler, J3
Tsur, N1
Glick, Y1
Abuhasira, S1
Mizrachi, A1
Farrell, MS1
Kim, WC1
Stein, DM1
Kheirbek, T1
Jikaria, N1
Murray, B1
Martin, TJ1
Lueckel, SN1
Stephen, AH1
Monaghan, SF1
Adams, CA1
Grassin-Delyle, S2
Picetti, R2
Frimley, L1
Jarman, H1
McGuinness, W1
Moss, P1
Pott, J1
Tai, N1
Lamy, E1
Urien, S2
Prowse, D1
Thayne, A1
Gilliam, C1
Pynn, H1
Spinella, PC2
Thomas, KA1
Turnbull, IR1
Fuchs, A1
Bochicchio, K1
Schuerer, D1
Reese, S1
Coleoglou Centeno, AA1
Horn, CB1
Baty, J1
Shea, SM1
Meledeo, MA1
Pusateri, AE4
Levy, JH2
Cap, AP6
Bochicchio, GV2
Hanley, C1
Callum, J2
Jerath, A1
Meneses, E1
Boneva, D1
McKenney, M1
Elkbuli, A1
Rivas, L1
Estroff, J1
Sparks, A1
Nahmias, J1
Allen, R1
Smith, SR1
Kutcher, M1
Carter, K1
Grigorian, A1
Albertson, S1
Turay, D1
Quispe, JC1
Luo-Owen, X2
Vella, M1
Pascual, J1
Tororello, G1
Quattrone, M1
Bernard, A1
Ratnasekera, A1
Lee, A1
Tamburrini, D1
Rodriguez, C1
Harrell, K1
Jeyamurugan, K1
Bugaev, N1
Warner, A1
Weinberger, J1
Hazelton, JP1
Selevany, M1
Wright, F1
Kovar, A1
Urban, S1
Hamrick, A1
Mount, M1
Carrick, M1
Cullinane, DC1
Chang, G1
Jain, G1
Spalding, C1
Sarani, B1
Dhara, S1
Chapman, MP4
Richards, JE1
Fedeles, BT1
Chow, JH1
Morrison, JJ4
Renner, C1
Trinh, AT1
Schlee, CS1
Koerner, K1
Grissom, TE1
Betzold, RD1
Scalea, TM1
Kozar, RA1
Darioli, V1
Almuwallad, A1
Cole, E2
Ross, J2
Kozhimala, M1
Asselin, N1
Zonfrillo, MR1
Su, G1
Mabasa, VH1
Tallon, JM1
Acker, J1
Wan, W1
Jenneson, S1
Al-Jeabory, M1
Gasecka, A1
Wieczorek, W1
Mayer-Szary, J1
Jaguszewski, MJ1
Szarpak, L1
Keragala, CB1
Chapman, NG1
Nicholas, ERV1
van Wessem, KJP1
Leenen, LPH1
Duchesne, J1
Taghavi, S1
Ninokawa, S1
Harris, C1
Schroll, R1
McGrew, P1
McGinness, C1
Reily, R1
Guidry, C1
Tatum, D1
Garcés Garcés, FJ1
Corral Torres, E1
Simoes da Silva Pereira, EJ1
Hernández-Tejedor, A1
Diebel, LN1
Martin, JV1
Liberati, DM1
Gu, ZT1
Huang, QB1
Yang, H1
Vaezazizi, R2
Jabourian, N1
Jabourian, A2
Seiler, K1
Pennington, TW1
Yoshida-McMath, C1
Kissel, S2
Schulz-Costello, K1
Mistry, J1
Surrusco, MS1
O'Bosky, KR2
Van Stralen, D1
Ludi, D2
Sporer, K2
Benson, P1
Kwong, E2
Pitts, R1
Culhane, JT1
Hong, Y1
Cai, X1
Huebner, BR1
Stettler, GR1
Nunns, GR1
Einersen, PM1
Silliman, CC3
Howard, JT1
Stockinger, ZT1
Bailey, JA1
Gross, KR1
Gausden, EB1
Qudsi, R1
Boone, MD1
OʼGara, B1
Ruzbarsky, JJ1
Lorich, DG1
Naumann, DN1
Hazeldine, J1
Davies, DJ1
Bishop, J1
Midwinter, MJ3
Belli, A1
Harrison, P1
Lord, JM1
Herron, JBT1
French, R1
Gilliam, AD1
Johnston, LR1
Rodriguez, CJ2
Elster, EA1
Bradley, MJ1
Meizoso, JP1
Dudaryk, R1
Mulder, MB1
Ray, JJ1
Karcutskie, CA1
Eidelson, SA1
Namias, N1
Schulman, CI1
Proctor, KG1
Carroll, ND1
Restrepo, CS1
Stasik, CN1
Teng, Y1
Feng, C1
Liu, Y1
Jin, H1
Gao, Y1
Li, T1
Theusinger, OM1
Albrecht, R1
Mueller, S1
Spahn, DR2
Stein, P1
Gilley, M1
Beno, S2
Boutonnet, M1
Abback, P1
Le Saché, F1
Harrois, A1
Follin, A1
Imbert, N1
Trichereau, J1
Ausset, S3
El-Menyar, A2
Sathian, B2
Asim, M1
Latifi, R1
Al-Thani, H2
Wu, S1
Buoni, M1
Brummel-Ziedins, K1
Cohen, M1
Petzold, L1
Ng, M1
Perrott, J1
Burgess, S1
Khan, M1
Jehan, F1
Bulger, EM1
OʼKeeffe, T1
Holcomb, JB5
Wade, CE3
Schreiber, MA3
Maeda, T1
Michihata, N1
Sasabuchi, Y1
Matsui, H1
Ohnishi, Y1
Miyata, S1
Yasunaga, H1
Myers, SP1
Kutcher, ME1
Rosengart, MR1
Peitzman, AB1
Neal, MD1
Chapman, N1
Chico Fernández, M1
Mudarra Reche, C1
Mousselli, M1
Niknafs, N1
Burgett-Moreno, M1
Pennington, T1
Lee, T1
Boudreau, RM1
Deshpande, KK1
Day, GM1
Hinckley, WR1
Harger, N1
Pritts, TA1
Makley, AT1
Goodman, MD1
Fragoso-Iñiguez, M1
Kong, YW1
Sriram, G1
Lim, D1
Standing, JF1
Balvers, K2
Baksaas-Aasen, K2
van Dieren, S2
Gaarder, C2
Naess, PA1
Stanworth, S2
Johansson, PI5
Stensballe, J5
Slattery, C1
Kark, J1
Wagner, T1
Verma, K1
Guth, C1
Vassal, O1
Friggeri, A1
Wey, PF1
Decullier, E1
Drucker, NA1
Wang, SK1
Newton, C1
Hansen, KC2
Pieracci, FM1
Prudovsky, I1
Carter, D1
Kacer, D1
Palmeri, M1
Soul, T1
Kumpel, C1
Pyburn, K1
Barrett, K1
DeMambro, V1
Alexandrov, I1
Brandina, I1
Kramer, R1
Rappold, J1
Thaventhiran, AJ1
Davenport, RA1
Wahlen, BM1
Abdelrahman, H1
Peralta, R1
Rizoli, S3
Benipal, S1
Santamarina, JL1
Vo, L1
Girish, A1
Hickman, DA1
Banerjee, A3
Luc, N1
Ma, Y1
Miyazawa, K1
Sekhon, UDS1
Sun, M1
Huang, S1
Sen Gupta, A1
Trappey, AF1
Thompson, KM1
Stephenson, JT1
Nuno, MA1
Hewes, HA1
Meyers, SR1
Stanley, RM1
Galante, JM1
Kostousov, V1
Wang, YW1
Cotton, BA6
Matijevic, N1
Shakur, H13
Ker, K4
Coats, T7
Prat, N1
Pidcoke, HF1
Sailliol, A3
Ortmann, E1
Besser, MW1
Klein, AA1
Ross, JD3
Dubose, JJ3
Jansen, JO2
Rasmussen, TE2
Wells, JC1
Stevermer, JJ1
Napolitano, LM2
Perel, P7
Prieto-Merino, D4
Maung, AA1
Kaplan, LJ1
Bozzette, A1
Aeron-Thomas, A1
Alvarado, JC1
Dewan, Y3
Elsayed, HF1
Gogichaishvili, T2
Gupta, S2
Hunt, BJ4
Iribhogbe, P2
Izurieta, M2
Khamis, H2
Komolafe, EO1
Mantilla, JH1
Miranda, J2
Uribe, CH1
Olaomi, O2
Olldashi, F2
Ramana, PV2
Ravi, RR2
Goodloe, JM1
Howerton, DS1
McAnallen, D1
Reed, H1
Jacobs, IG2
Harvey, V1
Perrone, J1
Kim, P1
He, S1
Johnsson, H1
Zabczyk, M1
Hultenby, K1
Wallén, H1
Blombäck, M1
Porta, CR1
Nelson, D1
McVay, D1
Salgar, S1
Eckert, M1
Izenberg, S2
Martin, MJ2
Faraoni, D2
Van Der Linden, P1
Schöchl, H3
Schlimp, CJ3
Ostrowski, SR2
Jarman, J1
Brier, A1
Clayton, T1
Altman, DG1
Croft, P1
Douglas, I1
Hemingway, H1
Hingorani, A1
Morley, KI1
Riley, R1
Timmis, A1
Van der Windt, D1
Ackery, AD1
Ackery, A1
Strugo, R1
Abramovich, A1
Bogert, JN1
Harvin, JA2
Willett, K2
Eckert, MJ1
Wertin, TM1
Tyner, SD1
Nelson, DW1
Voelckel, W2
Simmons, J1
Sikorski, RA1
Pittet, JF1
Thomas, JE1
Peirce, CA1
Mims, MM1
Hudson, JA1
Podbielski, JM1
Gonzalez, E2
Sunde, G1
Hoffmann, C1
Plang, S1
Farrell, NM1
Wing, HA1
Burke, PA1
Huiras, P1
Stanworth, SJ2
Manno, D1
Edwards, P2
Gilmore, I1
Jairath, V1
Veitch, A1
Heier, HE1
Badloe, J1
Bohonek, M1
Cap, A1
Doughty, H1
Korsak, J1
Medby, C1
Pfaff, RM1
Rentas, FJ1
Schilha, M1
Söderström, T1
Paudyal, P1
Smith, J1
Robinson, M1
South, A1
Higginson, I1
Reuben, A1
Shaffee, J1
Black, S1
Logan, S1
Thurston, B1
Chowdhury, S1
Edu, S1
Nicol, AJ1
Navsaria, PH1
Jennings, JD1
Solarz, MK1
Haydel, C1
Tosounidis, TH1
Giannoudis, PV1
Gaines-Dillard, N1
Bartley, MK1
Rosini, JM1
Lewis, CJ1
Li, P1
Stewart, L1
Weintrob, AC1
Carson, ML1
Murray, CK1
Tribble, DR1
Yahata, M1
Sakamoto, Y1
Monuteaux, MC1
Goobie, SM1
Lee, L1
Galante, J1
Holmes, JF1
Wafaisade, A1
Lefering, R1
Bouillon, B1
Böhmer, AB1
Gäßler, M1
Ruppert, M1
Daniel, Y1
Habas, S1
Malan, L1
Escarment, J1
Peyrefitte, S1
Poole, D1
Cortegiani, A1
Chieregato, A1
Russo, E1
Pellegrini, C1
De Blasio, E1
Mengoli, F1
Volpi, A1
Grossi, S1
Gianesello, L1
Orzalesi, V1
Fossi, F1
Chiara, O1
Coniglio, C1
Gordini, G1
Studer, NM1
Yassin, AH1
Keen, DE1
Wong, H1
Curry, N1
Ramirez, RJ1
Thomas, S1
Moore, E1
Moore, H1
Piscoya, A1
Hake, D1
Son, M1
Pohlman, T1
Wegner, J1
Bryant, J1
Grassetto, A1
Davis, P1
Nielsen, N1
Crepinsek, A1
Shreve, JT1
Castellino, F1
Steinmetz, J1
Eaglestone, S1
Zickenrott, V1
Greb, I1
Henkelmann, A1
Balzer, F1
Casu, S1
Kaufner, L1
von Heymann, C1
Zacharowski, K1
Weber, CF1
Cannon, JW1
Khan, MA1
Raja, AS1
Como, JJ1
Fox, EE1
Duchesne, JC1
Thomas, R1
Loudon, MA1
Brooks, A1
Brenni, M1
Worn, M1
Brüesch, M1
Ganter, MT1
Bautista, R1
Caballero, J1
El-Sayed, H1
Herrera, J1
Hunt, B2
Komolafe, E1
Marrero, MA1
Mejía-Mantilla, J1
Morales, C2
Peto, R1
Yutthakasemsunt, S1
Casati, V1
Romano, A1
Novelli, E1
D'Angelo, A1
Yeguiayan, JM2
Rosencher, N2
Freysz, M1
Daban, JL1
de Saint Maurice, G1
Blot, RM1
Chalmers, I1
Nicholl, J1
Afolabi, A1
Gando, S1
Guyatt, G1
Woolley, T1
Redman, T1
Schiessling, S1
Diener, MK1
Post, S1
Büchler, MW1
Seiler, CM1
Wikkelsø, AJ1
Afshari, A1
Sydenham, E1
Williams-Johnson, JA1
McDonald, AH1
Strachan, GG1
Williams, EW1
Nelson, R1
Ting, JY1
Vivien, B1
Baer, DG1
Orman, JA1
Aden, J1
Ryan, K1
Blackbourne, LH1
Fernández-Mondéjar, E1
Guerrero-López, F1
Marti, C1
Grosgurin, O1
Dami, F1
Rutz, P1
Carron, PN1
Rutschmann, O1
Kiriya, J1
Sorensen, B1
Fries, D1
Levi, M1
Godier, A1
Tobin, JM1
Varon, AJ1
Lecky, F1
Grottke, O1
Weiskopf, RB1
Bebarta, V1
Butler, F1
Cestero, RF1
Chaudry, IH1
Deal, V1
Dorlac, WC1
Gerhardt, RT1
Given, MB1
Hansen, DR1
Hoots, WK1
Klein, HG1
Macdonald, VW1
Mattox, KL1
Michael, RA1
Mogford, J1
Montcalm-Smith, EA1
Niemeyer, DM1
Prusaczyk, WK1
Rappold, JF2
Rassmussen, T1
Rentas, F1
Thompson, C1
Tucker, LD1
Piot, P1
Horton, R1
Krug, E1
Mersch, J1
Georgiou, C1
Neofytou, K1
Demetriades, D1
Dirkmann, D1
Radü-Berlemann, J1
Görlinger, K1
Peters, J1
Gumbert, S1
Murphy, DP1
O'Donnell, T1
McDonnell, J1
McElwain, JP1
Arango, M1
Dyer, O1
Ryan, KL1
Cortez, DS1
Dick, EJ1
Mattsson, J1
Peterson, HI1
Risberg, B2

Clinical Trials (51)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study[NCT04846114]71 participants (Actual)Interventional2016-03-31Completed
TRACE STUDY: A Randomized Controlled Trial Using Tranexamic Acid in the Treatment of Subdural Hematoma[NCT05713630]Phase 3130 participants (Anticipated)Interventional2024-03-31Not yet recruiting
Usage of Tranexamic Acid During Colonic Endoscopic Resection Procedures for Reduction Intraprocedural and Postprocedural Bleeding[NCT05345613]Phase 4200 participants (Anticipated)Interventional2022-05-01Recruiting
Tranexamic Acid for the Treatment of Postpartum Haemorrhage: An International Randomised, Double Blind, Placebo Controlled Trial[NCT00872469]Phase 320,060 participants (Actual)Interventional2009-05-31Completed
A Large Randomised Placebo Controlled Trial Among Trauma Patients With, or at Risk of, Significant Haemorrhage, of the Effects of Antifibrinolytic Treatment on Death and Transfusion Requirement[NCT00375258]Phase 320,211 participants (Actual)Interventional2005-05-31Completed
Pharmacokinetics of Intramuscular Tranexamic Acid in Trauma Patients: a Clinical Trial[NCT03875937]Phase 1/Phase 231 participants (Actual)Interventional2019-09-17Completed
Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury (TAMPITI TRIAL)[NCT02535949]Phase 2150 participants (Actual)Interventional2016-02-29Completed
"External Validation of the Clinical Pre-hospital Red- Flag Alert for Activation of Intra-hospital Hemorrhage Control Response in Blunt Trauma. A Prospective Multicentric Study"[NCT05820217]630 participants (Anticipated)Observational2023-05-10Not yet recruiting
Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973]Phase 3220 participants (Actual)Interventional2018-12-02Completed
Tranexamic Acid in Prehospital and In Hospital Civilian Trauma Care in Antifibrinolytic Therapy Study[NCT03469947]Phase 3200 participants (Actual)Interventional2015-03-31Active, not recruiting
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238]Phase 2130 participants (Anticipated)Interventional2023-04-12Recruiting
Post-Injury Platelet Biology: Mechanisms and Outcomes[NCT03682757]367 participants (Actual)Observational2018-09-20Completed
Evaluation of a Transfusion Therapy Using Whole Blood Versus Fractionated Blood Products in the Management of Coagulopathy in Patients Admitted to Hospital for Acute Traumatic Hemorrhage[NCT04431999]Phase 3200 participants (Anticipated)Interventional2021-12-04Recruiting
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321]60 participants (Actual)Interventional2022-03-24Completed
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC): A Pilot and Feasibility Study[NCT02840097]Phase 231 participants (Actual)Interventional2019-03-04Completed
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC): An Efficacy Study[NCT04387305]Phase 32,000 participants (Anticipated)Interventional2024-10-01Not yet recruiting
Evaluation of the Minimum Concentration of Tranexamic Acid Required to Inhibit Fibrinolysis in a Population of Pregnant Women at Term.[NCT02579941]40 participants (Actual)Interventional2015-11-30Completed
Prophylactic Use of Topical Tranexamic Acid to Aid Surgical Haemostasis During Caesarean Sections in Parturients With Moderate to High Risk of Bleeding[NCT02492087]Phase 384 participants (Anticipated)Interventional2015-08-31Recruiting
Tranexamic Acid's Effects in Patients Undergoing Laparoscopic Radical Prostatectomy: a Randomized, Double-blind, Placebo-controlled Trial[NCT05816668]Phase 3122 participants (Anticipated)Interventional2023-04-30Not yet recruiting
A Multi-centre Randomised, Double-blinded, Placebo-controlled Trial of Pre-hospital Treatment With Tranexamic Acid for Severely Injured Patients at Risk of Acute Traumatic Coagulopathy.[NCT02187120]Phase 31,310 participants (Actual)Interventional2014-07-28Completed
Recombinant Activated Factor VII (rFVIIa/ NovoSeven®) in the Management of Massive Bleeding in Hospital Universiti Sains Malaysia[NCT03251547]76 participants (Actual)Observational2017-08-21Completed
The Relationship Between the Use of a Continuous a Zero-heat Flux Temperature Monitor on Initial Discharge Hypothermia Rate Among Severely Injured Trauma Patients: a Randomized Controlled Trial. (RUZIT Trial)[NCT03313258]0 participants (Actual)Interventional2018-07-01Withdrawn (stopped due to PI left institution)
The Effect of Red Blood Cells Transfusion in Trauma Patients: A Risk Stratified Analysis[NCT01746953]20,211 participants (Actual)Observational2005-05-31Completed
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527]Phase 4100 participants (Anticipated)Interventional2019-10-07Recruiting
Randomized Control Trial Investigating for Prophylactic Tranexamic Acid Use at Time of Minimally Invasive Myomectomies[NCT04311073]Phase 350 participants (Anticipated)Interventional2020-06-20Recruiting
Efficacy of Intraoperative Use of Tranexamic Acid in Reducing Blood Loss During Telescoping Nail Application in Osteogenesis Imperfecta - Randomized Control Trials[NCT05321199]20 participants (Actual)Interventional2022-05-01Completed
Comparative Study For Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section: A Randomised Controlled Trial[NCT02739815]Phase 4200 participants (Actual)Interventional2016-04-30Completed
Tranexamic Acid Versus Novel Uterine Cooling Technique in Reducing Blood Loss and Incidence of Postpartum Hemorrhage at Caesarean Section[NCT02780245]Phase 4100 participants (Actual)Interventional2016-06-30Completed
Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage: A Randomized, Double-blinded, Placebo-controlled Pilot Trial[NCT03069859]Phase 231 participants (Actual)Interventional2018-03-06Active, not recruiting
[NCT01938768]110 participants (Actual)Observational2013-11-30Completed
Peroperative Tranexamic Acid as Prophylaxis of Haemorrhage in Benign Hysterectomy - a Randomized, Placebo-controlled Trial[NCT01940419]Phase 4332 participants (Actual)Interventional2013-04-30Completed
IV Tranexamic Acid Prior to Hysterectomy for Reduction of Intraoperative Blood Loss: A Randomized Placebo-Controlled Trial[NCT02911831]Early Phase 171 participants (Actual)Interventional2016-11-30Completed
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
Range of Motion and Function Following Primary Repair of Traumatic Zone 1 or Zone 2 Digit Flexor Tendon Injuries - Impact of Tranexamic Acid Use - A Prospective Study[NCT04178655]Early Phase 148 participants (Anticipated)Interventional2019-11-30Not yet recruiting
The Effect of Tranexamic Acid on Blood Loss and Transfusion Rates in Major Oncologic Surgery[NCT01980355]76 participants (Actual)Interventional2012-06-12Completed
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean Delivery: A Randomized Controlled Trial[NCT03364491]Phase 311,000 participants (Actual)Interventional2018-03-15Completed
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma. A Double-blind, Placebo-controlled, Multicentre, Randomized Controlled Clinical Trial[NCT03582293]Phase 3140 participants (Anticipated)Interventional2018-06-19Recruiting
Pre-hospital Administration of Tranexamic Acid for Adults With Moderate and Severe Traumatic Brain Injury: a Randomized, Double-blinded, Placebo-controlled Trial[NCT02645552]Phase 3400 participants (Anticipated)Interventional2016-01-31Not yet recruiting
Single Centre Randomised Controlled Trial to Assess the Effect of the Addition of Twenty-four Hours of Oral Tranexamic Acid Post-operatively to a Single Intra-operative Intravenous Dose of Tranexamic Acid on Calculated Blood Loss Following Primary Hip and[NCT03690037]Phase 41,089 participants (Actual)Interventional2016-07-07Completed
Blood Loss Reduction After Total Knee Arthroplasty. A Comparison Between Topical Tranexamic Acid and Platelet Rich Plasma: Controlled Clinical Trial[NCT02650856]Phase 340 participants (Actual)Interventional2015-09-30Completed
A Novel Technique Of Uterine Cooling During Repeated Cesarean Section For Reducing Blood Loss[NCT03793153]99 participants (Actual)Interventional2018-12-19Completed
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
The Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin / Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: a Prospective, Randomized, Double-blinded, Multicenter Study[NCT05357079]Early Phase 198 participants (Anticipated)Interventional2017-08-25Recruiting
Prevention of Postpartum Hemorrhage With Tranexamic Acid (TXA)[NCT03326596]Phase 41,000 participants (Anticipated)Interventional2018-04-20Recruiting
The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures.[NCT04488367]Early Phase 1120 participants (Anticipated)Interventional2020-07-06Recruiting
The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery[NCT01728636]Phase 261 participants (Actual)Interventional2013-01-15Completed
The Effect of Tranexamic Acid (TXA) on Blood Loss in Burn Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT03113253]Phase 4121 participants (Actual)Interventional2016-09-22Active, not recruiting
Role of Tranexamic Acid for Reducing Blood Loss in Patients Undergoing Major Gastro-intestinal Surgery[NCT01655641]Phase 2/Phase 3118 participants (Anticipated)Interventional2012-07-31Active, not recruiting
Tranexamic Acid in Knee Joint Surgery - a Randomised Controlled Trial[NCT02278263]Phase 4150 participants (Actual)Interventional2014-12-31Completed
The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816]25 participants (Actual)Interventional2016-04-30Terminated (stopped due to Study enrollment and goals unable to be reached.)
Estimation of Coagulation Factor XIII Activity Based on the Initial Plasma Fibrinogen Level in Trauma[NCT03634215]357 participants (Actual)Observational2018-09-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"Change in HLA-DR Expression on Monocytes 72 Hours After Drug or Placebo Administration in Patient Groups (0g TXA (Placebo); 2g TXA; 4g TXA)."

"Blood was drawn from patients at baseline (0 h, just before placebo or drug administration) and at 72 hours post placebo or drug administration. Leukocytes in these blood samples were stained with fluroescent antibodies specific for CD45, CD14, and HLA-DR, analyzed by flow cytometry, and the median fluorescen intensity (MFI) of HLA-DR signal was recorded for monocytes (CD45+CD14+). The fold change in HLA-DR expression from prior to placebo/drug administration to 72 h after placebo/drug administration (0 h : 72 h) was calculated as HLA-DR MFI72hours ÷ HLA-DR CD14 MFI0hours. Non-paramteric one-way ANOVA (Kruskal-Wallis test) was performed between each treatment group at the given time pont, and the p-value reported." (NCT02535949)
Timeframe: Samples Drawn through 72 hours after study initiation

Interventionfold change (Median)
Tranexamic Acid 2 Gram0.503
Tranexamic Acid 4 Gram0.509
Placebo0.532

CL- Clearance of TXA (mL/(Min*70kg))

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~CL equals clearance of TXA in mL/(min*70kg)." (NCT02535949)
Timeframe: 24 hours

InterventionmL/(min*70kg) (Mean)
Tranexamic Acid 2 Gram and 4 Gram109

Creatinine Count CL

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~Creatinine Count CL equals clearance (CL) affected by the covariate of Creatinine levels (SCRint). This value is unitless per NONMEM reporting." (NCT02535949)
Timeframe: 24 hours

Interventionunitless (Mean)
Tranexamic Acid 2 Gram and 4 Gram-0.084

Determine the Incidence of All Adverse Events in All Three Study Groups

All adverse events were totaled for each of the three study groups based on the number of incidents. (NCT02535949)
Timeframe: Hospital Discharge (average 10 days)

Interventionevents (Number)
Tranexamic Acid 2 Gram168
Tranexamic Acid 4 Gram264
Placebo138

Determine the Incidence of Seizures at 24 Hours in All Three Study Groups.

The incidence of seizures at 24 hours in all three study groups. Number of participants with seizures are reported (NCT02535949)
Timeframe: 24 hours following TXA

InterventionParticipants (Count of Participants)
Tranexamic Acid 2 Gram0
Tranexamic Acid 4 Gram1
Placebo0

Determine the Incidence of Thromboembolic Events (DVT, MI, PE, Stroke) in All Three Study Groups.

The number of events per group for the incidence of thromboembolic events (DVT, MI, PE, Stroke) in all three study groups. (NCT02535949)
Timeframe: Hospital Discharge (average 10 days)

Interventionevents (Number)
Tranexamic Acid 2 Gram13
Tranexamic Acid 4 Gram16
Placebo6

Near Infrared Spectroscopy CL

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~Near Infrared Spectroscopy CL equals clearance (CL) affected by the covariate of Near Infrared Spectroscopy (NIRSint). This value is unitless per NONMEM reporting." (NCT02535949)
Timeframe: 24 hours

Interventionunitless (Mean)
Tranexamic Acid 2 Gram and 4 Gram-0.27

Platelet Count CL

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~Platelet Count CL equals clearance (CL) affected by the covariate of Platelet Count (PLTint). This value is unitless per NONMEM reporting." (NCT02535949)
Timeframe: 24 hours

Interventionunitless (Mean)
Tranexamic Acid 2 Gram and 4 Gram0.45

Q- Intercompartmental Clearance (L/70kg)

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~Q equals intercompartmental clearance in L/70kg." (NCT02535949)
Timeframe: 24 hours

InterventionL/70kg (Mean)
Tranexamic Acid 2 Gram and 4 Gram174

Total Transfusion Volume CL

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~Total Transfusion Volume CL equals clearance (CL) affected by the covariate of Total Transfusion Volume (TxTot). This value is unitless per NONMEM reporting." (NCT02535949)
Timeframe: 24 hours

Interventionunitless (Mean)
Tranexamic Acid 2 Gram and 4 Gram0.03

V1- Central Volume (L/70kg)

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~V1 equals central volume in L/70kg." (NCT02535949)
Timeframe: 24 hours

InterventionL/70kg (Mean)
Tranexamic Acid 2 Gram and 4 Gram1160

V2- Peripheral Volume (L/70kg)

"Pharmacokinetic data was analyzed with NONMEM, using both the first-order and conditional non-Laplacian (with centering) estimation techniques. We considered two- and three-compartment models, parameterized in terms of both compartment volumes and clearances (distribution and elimination). We compared a basic model (in which pharmacokinetic parameters were independent of weight) to a model in which the pharmacokinetic parameters were assumed to be proportional to weight. The optimal model was selected on the basis of the objective function logarithm of the likelihood of the results) using standard criteria (NONMEM guide).~Equations from optimal model:~CL=109*((WT/70)**0.75) * (SCRint^-0.084) * ((NIRSInt)/96)^ -0.27 ) * ((PLTint)/130)^0.45) V1=1,160*(WT/70) * (TxTot)^0.03) Q=174*((WT/70)**0.75) V2=1080 *(WT/70)~V2 equals Peripheral Volume in L/70kg." (NCT02535949)
Timeframe: 24 hours

InterventionL/70kg (Mean)
Tranexamic Acid 2 Gram and 4 Gram1080

Differences in Cytokine Profiles Between the Three Study Groups

"To evaluate the effects of TXA on immune function parameters we will, in a RCT, analyze samples from 150 patients (50 in each study group), at multiple time points. Parameters are:~a. Cytokines measured from time 0 to 72 hours." (NCT02535949)
Timeframe: Samples Drawn through 72 hours after study initiation

,,
Interventionpg/mL (Median)
ITAC hour 0ITAC hour 72GM-CSF hour 0GM-CSF hour 72Factalkine hour 0Factalkine hour 72IFNgamma hour 0IFNgamma hour 72IL-10 hour 0IL-10 hour 72MIP-3a hour 0MIP-3a hour 72IL-12p70 hour 0IL-12p70 hour 72IL-13 hour 0IL-13 hour 72IL -17A hour 0IL-17A hour 72IL-1beta hour 0IL-1beta hour 72IL-2 hour 0IL-2 hour 72IL-21 hour 0IL-21 hour 72IL-4 hour 0IL-4 hour 72IL-23 hour 0IL-23 hour 72IL-5 hour 0IL-5 hour 72IL-6 hour 0IL-6 hour 72IL-7 hour 0IL-7 hour 72IL-8 hour 0IL-8 hour 72MIP-1alpha hour 0MIP-1alpha hour 72MIP-beta hour 0MIP-beta hour 72TNFa hour 0TNFa hour 72
Placebo29.3421.5864.6961.41141.8100.5117.4712.98105.0732.3822.9531.548.787.589.0810.2818.73143.93.114.014.127.025.5158.1635.53406.46399.749.068.3263.5641.916.5216.813.7817.6427.8525.4735.4428.1516.416.16
Tranexamic Acid 2 Gram34.2425.6767.7969.22223.61174.9123.4617.89115.9831.7622.9538.499.59.6711.811.1121.5120.064.174.154.174.266.286.4469.4549.99724.45589.739.38.6854.4873.9718.5318.4715.2526.932.5728.5744.9136.7819.1619.38
Tranexamic Acid 4 Gram32.7521.6967.5852.88146.23124.2317.5914.7984.3942.3921.9427.618.649.4511.1110.2715.0516.673.753.444.293.496.136.9558.2440.5428.26351.479.488.0539.767.9515.3316.2413.5923.0530.9827.2437.6629.0216.420.09

Differences in Leukocyte Function Parameters Between the Three Study Groups

"To evaluate the effects of TXA on immune function parameters we will, in a RCT, analyze samples from 150 patients (50 in each study group), at multiple time points. Parameters are:~a. Flow cytometric analyses on leukocytes measured from time 0 to 72 hours." (NCT02535949)
Timeframe: Samples Drawn through 72 hours after study initiation

,,
InterventionFold Change (Median)
CD 11b+CD 16+
Placebo0.8440.817
Tranexamic Acid 2 Gram0.8750.917
Tranexamic Acid 4 Gram0.9670.870

Blood Transfusion

Total volume of packed red blood cells, platelets, fresh frozen plasma, and cryoprecipitate (NCT02840097)
Timeframe: First 48 hours after randomization

Interventionml (Mean)
Tranexamic Acid Dose A367.4
Tranexamic Acid Dose B150.4
Placebo303.6

Intracranial Hemorrhage Progression

Intracranial hemorrhage progression on cranial computed tomography (CT) imaging; hemorrhage will be measured using the ABC/2 volume estimation and relative to the total brain volume (calculated by the XYZ/2 volume estimation); more intracranial hemorrhage progression represents a worse outcome. Change is calculated as the difference between the baseline and repeat cranial CT imaging. The repeat CT is conducted 24 hours (±6 hours) after the baseline CT. (NCT02840097)
Timeframe: 24 hours (±6 hours)

InterventionProportional change (Mean)
Tranexamic Acid Dose A0.003
Tranexamic Acid Dose B0.001
Placebo0.003

Number of Participants With Any Non-cerebral Venous or Arterial Thrombosis

Any non-cerebral venous or arterial thrombosis on standard diagnostic imaging post-randomization (NCT02840097)
Timeframe: Day 7 of hospitalization or hospital discharge (whichever comes first)

InterventionParticipants (Count of Participants)
Tranexamic Acid Dose A0
Tranexamic Acid Dose B0
Placebo0

Number of Participants With Seizures

Clinical or electroencephalogram-documented (NCT02840097)
Timeframe: 24 hours after receiving drug

InterventionParticipants (Count of Participants)
Tranexamic Acid Dose A0
Tranexamic Acid Dose B0
Placebo1

Pediatric Quality of Life Inventory (PedsQL)

Neurocognitive functioning and quality-of-life measures; range from 0 to 100 quality of life units with higher scores representing better outcomes. Measurements occur at 1 week, 1 month, 3 months, and 6 months to generate an area under the curve of quality of life units. (NCT02840097)
Timeframe: 6 months

InterventionQuality of life units * months (Mean)
Tranexamic Acid Dose A64.9
Tranexamic Acid Dose B60.2
Placebo67.2

Digit Span Recall Test

Test of working memory; higher scores represent a better outcome, range from 0 to infinity (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionscore on a scale (Mean)
Total forward digit span, 1 weekTotal backward digit span, 1 weekTotal forward digit span, 1 monthTotal backward digit span, 1 monthTotal forward digit span, 3 monthsTotal backward digit span, 3 monthsTotal forward digit span, 6 monthsTotal backward digit span, 6 months
Placebo8.87.37.55.38.66.58.45.8
Tranexamic Acid Dose A8.46.07.26.29.18.711.710.4
Tranexamic Acid Dose B8.46.07.96.210.47.810.06.0

Glasgow Outcome Scale-Extended (GOS-E) Peds

Global functioning; range is 1 to 8 with higher scores representing better outcomes; 1=death, 2=vegetative state, 3=lower severe disability, 4=upper severe disability, 5=lower moderate disability, 6=upper moderate disability, 7=lower good recovery, 8=upper good recovery (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionscore on a scale (Mean)
1 week1 month3 months6 months
Placebo5.34.54.24.3
Tranexamic Acid Dose A4.64.93.83.7
Tranexamic Acid Dose B5.25.14.62.9

Pediatric Quality of Life Inventory (PedsQL)

Neurocognitive functioning and quality-of-life measures; range from 0 to 100 with higher scores representing better outcomes (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionunits on a scale (Mean)
1 week1 month3 months6 months
Placebo57.960.568.968.9
Tranexamic Acid Dose A43.757.077.381.6
Tranexamic Acid Dose B52.461.577.584.3

Estimated Blood Loss

Surgical blood loss estimation (NCT01980355)
Timeframe: From time of surgery to 90 days post hospital discharge

InterventionmL (Median)
Tranexamic Acid450
Placebo365

Number of Participants Who Required Transfusion

To determine the impact of perioperative administration of tranexamic acid on blood loss and transfusion rates in major oncologic surgery (NCT01980355)
Timeframe: From time of surgery to 90 days post hospital discharge

InterventionParticipants (Count of Participants)
Tranexamic Acid8
Placebo5

Change in Hemoglobin

[Key secondary outcome] Change in hemoglobin from the most recent measured before delivery to lowest measured in the 48 hours after delivery (NCT03364491)
Timeframe: from 4 weeks before delivery to 48 hours postpartum

Interventiongrams per deciliter (Mean)
Tranexamic Acid-1.8
Placebo-1.9

Length of Stay

Mother's length of stay from delivery to discharge (NCT03364491)
Timeframe: Until hospital discharge, an average of 3 days

Interventiondays (Median)
Tranexamic Acid3
Placebo3

Number of Mothers Who Died or Had Thromboembolic Events (Venous or Arterial), Ischemic Stroke, Myocardial Infarction, New-onset Seizure Activity, or Were Admitted to the Intensive Care Unit for More Than 24 Hours

(NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid35
Placebo32

Number of Participants Who Received Open Label TXA or Other Antifibrinolytic

This is the number of mothers who were treated with any amount of open-label TXA (not blinded study drug) or another antifibrinolytic (eg., Amicar) (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid108
Placebo109

Number of Participants Who Received Surgical or Radiologic Interventions to Control Bleeding and Related Complications

This is the number of mothers who required any of the following types of surgical procedures to control bleeding: laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid233
Placebo231

Number of Participants Who Received Treatments and Interventions in Response to Bleeding and Related Complications

[Key secondary outcome] This is the number of mothers who received treatments and interventions to control bleeding such as: uterotonics such as prostaglandins or methergine, but excluding oxytocin; open label TXA or other antifibrinolytics; transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets or administration of any factor concentrates; laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid892
Placebo986

Number of Participants Who Were Transfused With 4 or More Units of Packed Red Blood Cells

Participants were categorized according to the amount of packed red blood cells or whole blood transfused, either as 0 to 3 units, or 4 or more units (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid20
Placebo19

Number of Participants Who Were Transfused With Other Blood Products

This is the number of mothers who received during the first 7 days after delivery a transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets, or received any factor concentrates (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid29
Placebo31

Number of Participants Who Were Treated With Uterotonics Other Than Oxytocin

This is the number of mothers who were treated with uterotonics such as prostaglandins or methergine, but excluding oxytocin, from delivery through 48 hours after delivery. (NCT03364491)
Timeframe: within 48 hours postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid649
Placebo732

Number of Participants With a Thromboembolic Event (Venous or Arterial), Ischemic Stroke, or Myocardial Infarction

[Key secondary outcome] This is the number of mothers who experienced a thromboembolic event, ischemic stroke, or myocardial infarction during the 6 weeks after delivery. (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid12
Placebo13

Number of Participants With Estimated Blood Loss Greater Than 1 Liter During Delivery

[Major secondary outcome] The surgeon or anesthesiologist estimated the blood loss during the delivery in milliliters, which was recorded in the anesthesia record and/or operative report (NCT03364491)
Timeframe: From skin incision to transfer from operating room, average of 1 hour

InterventionParticipants (Count of Participants)
Tranexamic Acid339
Placebo368

Number of Participants With Maternal Death or Transfusion of Packed Red Blood Cells

Participants were monitored from delivery until hospital discharge or 7 days after delivery (postpartum), whichever is sooner. This is the number of mothers who died for any reason, or had a blood transfusion of 1 or more units (of packed red blood cells, including whole blood or cell saver). (NCT03364491)
Timeframe: by hospital discharge or by 7 days postpartum, whichever is sooner

InterventionParticipants (Count of Participants)
Tranexamic Acid201
Placebo233

Number of Participants With Postpartum Infectious Complications

[Key Secondary Outcome] This is the number of mothers who experienced any of the following infectious complications in the 6 weeks after delivery: endometritis, surgical site infection, pelvic abscess (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid162
Placebo125

Number of Participants With Seizure Activity That Was Not Seen Prior to Study Enrollment

This is the number of mothers who experienced seizure activity, confirmed by central review, whose onset is after enrollment (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid2
Placebo0

Therapeutic Effect on Drainage Quantification

The blood quantification will be taken at 6am every day. (NCT02650856)
Timeframe: up to 2nd day post operative (24 and 48 hrs)

,
InterventionmL (Mean)
24 hours48 hours
Group 1 Tranexamic Acid246.4120.8
Group 2 Platelet Rich Plasma263.2140.2

Therapeutic Effect on Hematocrit Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventionpercentage of Hematocrite (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid41.731.629.128.6
Group 2 Platelet Rich Plasma41.529.827.727.3

Therapeutic Effect on Hemoglobin Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventiong/dL (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid13.610.39.59.3
Group 2 Platelet Rich Plasma13.69.99.29.1

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Additional Blood Products Transfused

Total additional blood products (fresh frozen plasma, cryoprecipitate, and platelets) transfused in the perioperative period measured in units. (NCT01728636)
Timeframe: 24 hours after skin incision

InterventionUnits (Mean)
Tranexamic Acid1
Placebo2

Estimated Intraoperative Blood Loss

Estimated Intraoperative blood loss in milliliters (mLs) (NCT01728636)
Timeframe: Incision to skin closure (approximately 10 hours)

InterventionMilliliters (Mean)
Tranexamic Acid1550
Placebo1600

Post Operative Major Morbidity

Number of participants who experienced arterial or venous thromboembolism, neurologic complications (including stroke, seizure,and delirium), infections, and pulmonary renal or cardiac adverse outcomes (demand ischemia, myocardial infarction or new arrhythmia) before another operative procedure or hospital discharge. (NCT01728636)
Timeframe: Time of surgery to date of discharge from hospital (average 7 days)

InterventionParticipants (Count of Participants)
Tranexamic Acid9
Placebo9

Total Operating Room Time

Total operating room time from incision to closure of incision in minutes. (NCT01728636)
Timeframe: Minutes

InterventionMinutes (Median)
Tranexamic Acid602
Placebo576

Total Red Blood Cells Transfused in the Intraoperative Period

Total red blood cells transfused in the intraoperative period in (mL). Total RBC equal packed red blood cells and cell saver infusion. (NCT01728636)
Timeframe: Intraoperative period (approximately 12 hours)

Interventionmilliliters (Median)
Tranexamic Acid1140
Placebo1460

Total Tranexamic Acid Dose (mg)

Total milligrams of intravenous tranexamic acid administered during the surgical procedure. (NCT01728636)
Timeframe: Intraoperative period

Interventionmilligrams (Median)
Tranexamic Acid1408
Placebo0

Blood Loss

"The loss of haemoglobin (Hb) was then estimated according to the formula:~Hb(loss) = Blood volume (BV) x (Hbi-Hbe) x 0.001+Hbt~where Hb (loss) (g) is the amount of Hb lost, Hbi (g/L) the Hb concentration before surgery, Hbe (g/L) is the Hbe concentration on the third day after surgery, and Hbt (g) is the total amount of allogeneic Hb transfused. A unit of banked blood is considered to contain a minimum of 40g Hb (Blood component data sheet, New Zealand Blood Services [NZBS]). All units of blood are processed and stored in a nationally standardised manner. The blood loss (ml) was related to the patient's preoperative Hb value (g/L):~Blood loss =1000 x Hb(loss) /Hbi" (NCT02278263)
Timeframe: Post operative day 3

Interventionmls (Mean)
Control1090
Intraarticular716
Systemic746

Length of Stay (LOS)

Day of surgery is counted as Day 0. (NCT02278263)
Timeframe: Average length of stay is expected to be 3 to 5 days

Interventiondays (Median)
Control4
Topical4
Systemic4

Number of Participants Receiving Allogenic Blood Transfusion

"Those patients receiving blood products. Standardised protocol is as follows:~The criterion for transfusion of blood products will be a haemoglobin < 80g/L or a haemoglobin <100g/L in a patient with ischaemic heart disease or with significant symptomatology" (NCT02278263)
Timeframe: Participants will be followed for the duration of their hospital stay expected to be an average of 3-5 days

InterventionParticipants (Count of Participants)
Control2
Topical1
Systemic0

Perioperative Fluid Administration

Intravenous fluid (excluding blood transfusion) given during and first 24 hours after surgery (NCT02278263)
Timeframe: Day 1

Interventionmls (Mean)
Control1765
Topical1613
Systemic1807

Number of Participants Experiencing Symptomatic Venothromboembolic (VTE) Disease

Rates of deep vein thrombosis (DVT) and pulmonary embolus (PE) in each group recorded as a percentage (NCT02278263)
Timeframe: Postoperatively within 30 days after surgery

,,
InterventionParticipants (Count of Participants)
DVTPE
Control00
Systemic01
Topical02

Range of Active Flexion

Range of motion measured in degrees on postoperative days 1-3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control577175
Systemic587278
Topical657582

Range of Passive Flexion

Range of motion measured in degrees for postoperative days 1 to 3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control657682
Systemic688087
Topical748187

Blood Transfusion Rates, Defined Nominally (Binary) as Having at Least One Transfusion

To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge

InterventionPatients with 1 or more transfusions (Number)
Tranexamic Acid2
Placebo3

Effect of Tranexamic Acid on the Total Length of Hospital Admission for a Large (350 cm2) Burn Injury

To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge

InterventionDays (Median)
Tranexamic Acid23
Placebo9

Intraoperative Blood Loss in mL

To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes

InterventionmL (Median)
Tranexamic Acid100
Placebo325

Reviews

69 reviews available for tranexamic acid and Wounds and Injuries

ArticleYear
Hemostatic Resuscitation in Children.
    Transfusion medicine reviews, 2021, Volume: 35, Issue:4

    Topics: Blood Transfusion; Child; Hemostatics; Humans; Resuscitation; Shock, Hemorrhagic; Tranexamic Acid; W

2021
Effects of tranexamic acid treatment in severely and non-severely injured trauma patients.
    Transfusion, 2022, Volume: 62 Suppl 1

    Topics: Antifibrinolytic Agents; Glasgow Coma Scale; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injurie

2022
Alternative blood products in trauma.
    Current opinion in anaesthesiology, 2023, Apr-01, Volume: 36, Issue:2

    Topics: Blood Coagulation Disorders; Fibrinogen; Hemorrhage; Hemostatics; Humans; Thrombelastography; Tranex

2023
Geographical Variance in the Use of Tranexamic Acid for Major Trauma Patients.
    Medicina (Kaunas, Lithuania), 2019, Sep-02, Volume: 55, Issue:9

    Topics: Antifibrinolytic Agents; Drug Utilization; Emergency Medical Services; Global Health; Hemorrhage; Hu

2019
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
Efficacy and safety of tranexamic acid in orthopaedic trauma surgery: a meta-analysis.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:24

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Orthopedic Procedures; Tra

2019
The Use of Tranexamic Acid (TXA) for the Management of Hemorrhage in Trauma Patients in the Prehospital Environment: Literature Review and Descriptive Analysis of Principal Themes.
    Shock (Augusta, Ga.), 2020, Volume: 53, Issue:3

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Humans; Shock, Hemorrhagic; Tranexamic Acid; Wo

2020
Intraosseous access in the resuscitation of trauma patients: a literature review.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2021, Volume: 47, Issue:1

    Topics: Analgesics; Anesthetics; Blood Transfusion; Catheters; Crystalloid Solutions; Equipment Design; Huma

2021
Limiting Blood Loss in Orthopaedic Trauma: Strategies and Effects.
    Injury, 2020, Volume: 51 Suppl 2

    Topics: Blood Coagulation Disorders; Hemostasis; Humans; Orthopedic Procedures; Resuscitation; Shock, Hemorr

2020
The impact of blood product ratio and procoagulant therapy on the development of thromboembolic events in severely injured hemorrhaging trauma patients.
    Transfusion, 2020, Volume: 60, Issue:8

    Topics: Antifibrinolytic Agents; Blood Coagulation Factors; Blood Component Transfusion; Factor VIIa; Fibrin

2020
Emergency Transfusions.
    Emergency medicine clinics of North America, 2020, Volume: 38, Issue:4

    Topics: Antifibrinolytic Agents; Blood Grouping and Crossmatching; Blood Transfusion; Catheterization, Centr

2020
Massive transfusion protocol in adult trauma population.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Compon

2020
The impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis.
    The journal of trauma and acute care surgery, 2021, 05-01, Volume: 90, Issue:5

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Hemorrhage; Humans; Randomized Controlled Trial

2021
Assessing the clinical utilization of tranexamic acid by paramedics for patients with major trauma (ACUTE).
    CJEM, 2021, Volume: 23, Issue:2

    Topics: Allied Health Personnel; Antifibrinolytic Agents; British Columbia; Hemorrhage; Humans; Infant, Newb

2021
Efficacy and safety of tranexamic acid in pediatric trauma patients: Evidence from meta-analysis.
    The American journal of emergency medicine, 2021, Volume: 49

    Topics: Adolescent; Antifibrinolytic Agents; Child; Child, Preschool; Female; Humans; Male; Pediatrics; Tran

2021
Plasminogen: an enigmatic zymogen.
    Blood, 2021, 05-27, Volume: 137, Issue:21

    Topics: Animals; Antifibrinolytic Agents; Brain; Conjunctivitis; Enzyme Activation; Fibrin; Fibrinolysin; Fi

2021
Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2017, Volume: 20, Issue:3

    Topics: Blood Coagulation Disorders; Blood Transfusion; Hemorrhage; Humans; Practice Guidelines as Topic; Re

2017
Tranexamic Acid in Orthopaedic Trauma Surgery: A Meta-Analysis.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Female; Humans; Male; Orthopedi

2017
Damage control resuscitation in pediatric trauma.
    Current opinion in pediatrics, 2018, Volume: 30, Issue:3

    Topics: Adolescent; Antifibrinolytic Agents; Blood Transfusion; Child; Child, Preschool; Female; Fluid Thera

2018
Efficacy of prehospital administration of tranexamic acid in trauma patients: A meta-analysis of the randomized controlled trials.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:6

    Topics: Antifibrinolytic Agents; Dose-Response Relationship, Drug; Emergency Medical Services; Hemorrhage; H

2018
What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2019, Volume: 30, Issue:1

    Topics: Antifibrinolytic Agents; Female; Fibrinolysis; Humans; Male; Postpartum Hemorrhage; Pregnancy; Tissu

2019
The Use of Tranexamic Acid to Reduce Surgical Blood Loss: A Review Basic Science, Subspecialty Studies, and The Evolution of Use in Spine Deformity Surgery.
    Clinical spine surgery, 2019, Volume: 32, Issue:2

    Topics: Arthroplasty; Blood Loss, Surgical; Dose-Response Relationship, Drug; Humans; Spine; Tranexamic Acid

2019
Pediatric trauma-related coagulopathy: Balanced resuscitation, goal-directed therapy and viscoelastic assays.
    Seminars in pediatric surgery, 2019, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Transfusion; Ch

2019
What's new for trauma haemorrhage management?
    British journal of hospital medicine (London, England : 2005), 2019, May-02, Volume: 80, Issue:5

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfusion; Hemorrhage; Hemostatic Tech

2019
Mortality and Thrombosis in Injured Adults Receiving Tranexamic Acid in the Post-CRASH-2 Era.
    The western journal of emergency medicine, 2019, Volume: 20, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Humans; Incidence; Mortality; Thrombosis; Tranexamic Acid; Trauma Se

2019
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2012, Volume: 12

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo

2012
[Evolution of US military transfusion support for resuscitation of trauma and hemorrhagic shock].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2013, Volume: 20, Issue:2

    Topics: Blood Coagulation Disorders; Blood Component Transfusion; Blood Transfusion; Forecasting; Hemostatic

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Tranexamic acid in trauma: how should we use it?
    The journal of trauma and acute care surgery, 2013, Volume: 74, Issue:6

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Thrombelastography; Tranexamic Acid; Treatment Outcome;

2013
Role of fibrinogen in massive injury.
    Minerva anestesiologica, 2014, Volume: 80, Issue:1

    Topics: Afibrinogenemia; Animals; Antifibrinolytic Agents; Blood Component Transfusion; Fibrin; Fibrinogen;

2014
Trauma and severe bleeding. Tranexamic acid within one hour to reduce mortality.
    Prescrire international, 2013, Volume: 22, Issue:140

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Severity of Illness Index; Thrombosis; Time Factors; Tr

2013
TXA: a difference-maker for trauma patients.
    JEMS : a journal of emergency medical services, 2013, Volume: 38, Issue:4

    Topics: Antifibrinolytic Agents; Decision Making; Emergency Treatment; Hemorrhage; Humans; Tranexamic Acid;

2013
Does the use of tranexamic acid improve trauma mortality?
    Annals of emergency medicine, 2014, Volume: 63, Issue:4

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injuries

2014
A systematic review of antifibrinolytics and massive injury.
    Minerva anestesiologica, 2014, Volume: 80, Issue:10

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Hemorrhage; Humans; Tranexamic Acid; Wounds an

2014
Tranexamic acid, fibrinogen concentrate, and prothrombin complex concentrate: data to support prehospital use?
    Shock (Augusta, Ga.), 2014, Volume: 41 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Coagulation Factors; Blood Transfusion; Brain Inju

2014
Viscoelastic guidance of resuscitation.
    Current opinion in anaesthesiology, 2014, Volume: 27, Issue:2

    Topics: Blood Transfusion; Fibrinolysis; Hemostasis; Humans; Resuscitation; Thrombelastography; Tranexamic A

2014
Tranexamic acid in pediatric trauma: why not?
    Critical care (London, England), 2014, Jul-02, Volume: 18, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Child; Hemorrhage; Hospital Mortality; Humans; Multicenter Studies a

2014
Tranexamic acid for trauma-related hemorrhage.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014, Oct-21, Volume: 186, Issue:15

    Topics: Antifibrinolytic Agents; Canada; Hemorrhage; Humans; Time Factors; Tranexamic Acid; Wounds and Injur

2014
Damage Control Resuscitation.
    Journal of intensive care medicine, 2016, Volume: 31, Issue:3

    Topics: Antifibrinolytic Agents; Blood Transfusion; Clinical Protocols; Crystalloid Solutions; Factor VIIa;

2016
Management of traumatic haemorrhage--the European perspective.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Blood Coagulation Disorders; Europe; Hemorrhage; Humans; Platelet Transfusion; Thrombin; Tranexamic

2015
Tranexamic acid: from trauma to routine perioperative use.
    Current opinion in anaesthesiology, 2015, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Hemostasis; Humans; Perioperative Care; Tranex

2015
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2015, May-09, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo

2015
Postinjury fibrinolysis shutdown: Rationale for selective tranexamic acid.
    The journal of trauma and acute care surgery, 2015, Volume: 78, Issue:6 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Fibrinolysin; Fibrinolysis; Humans; Plasminoge

2015
Tranexamic acid as part of remote damage-control resuscitation in the prehospital setting: A critical appraisal of the medical literature and available alternatives.
    The journal of trauma and acute care surgery, 2015, Volume: 78, Issue:6 Suppl 1

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Hemostatics; Humans; Resuscitation; Shock, Hemo

2015
Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Adult; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Tranexamic Acid;

2015
Tranexamic acid in trauma: how should we use it?
    Journal of thrombosis and haemostasis : JTH, 2015, Volume: 13 Suppl 1

    Topics: Animals; Antifibrinolytic Agents; Fibrinolysis; Hemorrhage; Humans; Patient Selection; Risk Assessme

2015
Application of Tranexamic Acid in Trauma and Orthopedic Surgery.
    The Orthopedic clinics of North America, 2016, Volume: 47, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Humans; Or

2016
Paediatric trauma resuscitation: an update.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2016, Volume: 42, Issue:3

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfusion; Child; Clinical Protocols;

2016
[Anti DIC therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2016
Tactical damage control resuscitation in austere military environments.
    Journal of the Royal Army Medical Corps, 2016, Volume: 162, Issue:6

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Component Tra

2016
Blood Component Therapy and Coagulopathy in Trauma: A Systematic Review of the Literature from the Trauma Update Group.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Component Transfusion; Humans; Mortality

2016
Blood products and procoagulants in traumatic bleeding: use and evidence.
    Current opinion in critical care, 2016, Volume: 22, Issue:6

    Topics: Blood Coagulation Disorders; Hemorrhage; Hemostasis; Humans; Plasma; Randomized Controlled Trials as

2016
Tranexamic Acid Update in Trauma.
    Critical care clinics, 2017, Volume: 33, Issue:1

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injuries

2017
Tranexamic Acid for Trauma Resuscitation in the United States of America.
    Seminars in thrombosis and hemostasis, 2017, Volume: 43, Issue:2

    Topics: Humans; Tranexamic Acid; United States; Wounds and Injuries

2017
[Haemostatic resuscitation in bleeding trauma patients].
    Ugeskrift for laeger, 2016, Dec-26, Volume: 178, Issue:52

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfusion; Critical Illness; Fluid The

2016
Damage control resuscitation for patients with major trauma.
    BMJ (Clinical research ed.), 2009, Jun-05, Volume: 338

    Topics: Acidosis; Blood Cells; Blood Coagulation Disorders; Calcium; Factor VIIa; Fibrinogen; Hemostasis; Hu

2009
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemorrhage; Humans; Ran

2011
Tranexamic acid for trauma patients: a critical review of the literature.
    The Journal of trauma, 2011, Volume: 71, Issue:1 Suppl

    Topics: Antifibrinolytic Agents; Clinical Trials as Topic; Hemorrhage; Humans; Injury Severity Score; Tranex

2011
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial.
    BMC emergency medicine, 2012, Mar-01, Volume: 12

    Topics: Antifibrinolytic Agents; Demography; Emergency Treatment; Global Health; Humans; Risk Factors; Shock

2012
Emerging treatment strategies for trauma-induced coagulopathy.
    The British journal of surgery, 2012, Volume: 99 Suppl 1

    Topics: Acidosis; Anemia; Antifibrinolytic Agents; Bandages; Blood Coagulation Disorders; Blood Coagulation

2012
Should antifibrinolytics be given in all patients with trauma?
    Current opinion in anaesthesiology, 2012, Volume: 25, Issue:3

    Topics: Antifibrinolytic Agents; Clinical Trials as Topic; Emergency Medical Services; Hemorrhage; Humans; T

2012
Review article: update in trauma anesthesiology: perioperative resuscitation management.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:6

    Topics: Anesthesia; Anesthesiology; Antifibrinolytic Agents; Blood Transfusion; Factor VIIa; Humans; Hypoten

2012
Coagulation management.
    Current opinion in critical care, 2012, Volume: 18, Issue:6

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Evidence-Based Medi

2012
Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities.
    Shock (Augusta, Ga.), 2013, Volume: 39, Issue:2

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Postoperative Complications; Randomized Controlled Tria

2013
Tranexamic acid in remote damage control resuscitation.
    Transfusion, 2013, Volume: 53 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Hemorrhage; Humans; Resuscitation; Tranexamic

2013
Potential value of pharmacological protocols in trauma.
    Current opinion in anaesthesiology, 2013, Volume: 26, Issue:2

    Topics: Blood Coagulation Disorders; Blood Transfusion; Cardiac Surgical Procedures; Fibrinogen; Hemostatics

2013
Local and systemic hemostatics as an adjunct to control bleeding in trauma.
    The American surgeon, 2013, Volume: 79, Issue:2

    Topics: Administration, Topical; Cellulose, Oxidized; Chitosan; Combined Modality Therapy; Factor VIIa; Fibr

2013
Potential value of protocols in substantially bleeding trauma patients.
    Current opinion in anaesthesiology, 2013, Volume: 26, Issue:2

    Topics: Blood Coagulation Disorders; Blood Coagulation Tests; Clinical Protocols; Hemorrhage; Humans; Thromb

2013
Treatment of anaemia in the polytrauma Jehovah's Witness.
    Irish medical journal, 2003, Volume: 96, Issue:1

    Topics: Anemia; Antifibrinolytic Agents; Blood Substitutes; Blood Transfusion; Fluorocarbons; Hemodilution;

2003

Trials

19 trials available for tranexamic acid and Wounds and Injuries

ArticleYear
Temporal Transitions in Fibrinolysis after Trauma: Adverse Outcome Is Principally Related to Late Hypofibrinolysis.
    Anesthesiology, 2022, 01-01, Volume: 136, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Tests; Cohort Studies; Female; Fibrinolysis; Hemor

2022
The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children.
    Trials, 2021, Nov-04, Volume: 22, Issue:1

    Topics: Antifibrinolytic Agents; Bayes Theorem; Child; Double-Blind Method; Hemorrhage; Humans; Tranexamic A

2021
Effect of age on the efficacy of tranexamic acid: An analysis of heterogeneity of treatment effect within the CRASH-2 dataset.
    The American journal of emergency medicine, 2022, Volume: 53

    Topics: Adult; Aged; Antifibrinolytic Agents; Bayes Theorem; Hemorrhage; Humans; Odds Ratio; Tranexamic Acid

2022
Tranexamic acid in pediatric hemorrhagic trauma.
    The journal of trauma and acute care surgery, 2023, 01-01, Volume: 94, Issue:1S Suppl 1

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Hemorrhage; Humans; Prospective Studies; Retro

2023
Prehospital Tranexamic Acid for Severe Trauma.
    The New England journal of medicine, 2023, Jul-13, Volume: 389, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Australia; Blood Coagulation Disorders; Emergency Medical Services;

2023
Introduction of a standardised protocol, including systematic use of tranexamic acid, for management of severe adult trauma patients in a low-resource setting: the MSF experience from Port-au-Prince, Haiti.
    BMC emergency medicine, 2019, 10-18, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Clinical Protocols; Developing Countries; Female;

2019
Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cohort Studies; Double-Blind Method; Female; Hemo

2020
Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cohort Studies; Double-Blind Method; Female; Hemo

2020
Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cohort Studies; Double-Blind Method; Female; Hemo

2020
Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.
    PloS one, 2020, Volume: 15, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cohort Studies; Double-Blind Method; Female; Hemo

2020
The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Administration, Intravenous; Double-Blind Method; Female; Hemorrhage; Humans; Interleukin-6; L-Selec

2020
The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial.
    Annals of emergency medicine, 2019, Volume: 74, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Cost-Benefit Analysis; Female; Hemorrhage; Humans; Male; Middle Aged

2019
Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial.
    Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:24

    Topics: Adult; Aged; Antifibrinolytic Agents; Female; Hemorrhage; Humans; Male; Middle Aged; Models, Theoret

2013
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
    PLoS medicine, 2014, Volume: 11, Issue:6

    Topics: Adult; Cause of Death; Erythrocyte Transfusion; Hemorrhage; Humans; Odds Ratio; Risk; Risk Assessmen

2014
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
    PLoS medicine, 2014, Volume: 11, Issue:6

    Topics: Adult; Cause of Death; Erythrocyte Transfusion; Hemorrhage; Humans; Odds Ratio; Risk; Risk Assessmen

2014
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
    PLoS medicine, 2014, Volume: 11, Issue:6

    Topics: Adult; Cause of Death; Erythrocyte Transfusion; Hemorrhage; Humans; Odds Ratio; Risk; Risk Assessmen

2014
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
    PLoS medicine, 2014, Volume: 11, Issue:6

    Topics: Adult; Cause of Death; Erythrocyte Transfusion; Hemorrhage; Humans; Odds Ratio; Risk; Risk Assessmen

2014
Tranexamic acid use in severely injured civilian patients and the effects on outcomes: a prospective cohort study.
    Annals of surgery, 2015, Volume: 261, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Drug Administration Schedule; F

2015
The impact of tranexamic acid on mortality in injured patients with hyperfibrinolysis.
    The journal of trauma and acute care surgery, 2015, Volume: 78, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospita

2015
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Male; Thrombosis; Tra

2010
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Adult; Antifibrinolytic Agents; Hemorrhage; Humans; Logistic Models; Time Factors; Tranexamic Acid;

2011
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2) A randomised, placebo-controlled trial.
    The West Indian medical journal, 2010, Volume: 59, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cause of Death; Chi-Square Distribution; Female;

2010
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial.
    BMC emergency medicine, 2012, Mar-01, Volume: 12

    Topics: Antifibrinolytic Agents; Demography; Emergency Treatment; Global Health; Humans; Risk Factors; Shock

2012
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial.
    BMJ (Clinical research ed.), 2012, Sep-11, Volume: 345

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Drug Administration Schedule; Female; Hemor

2012
The CRASH-2 trial of an antifibrinolytic agent in traumatic haemorrhage: an international collaboration.
    The Indian journal of medical research, 2007, Volume: 125, Issue:1

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; International Cooperation; Tranexamic Acid; World Healt

2007

Other Studies

129 other studies available for tranexamic acid and Wounds and Injuries

ArticleYear
Massive transfusion in trauma: an evolving paradigm.
    Minerva anestesiologica, 2022, Volume: 88, Issue:3

    Topics: Blood Coagulation Disorders; Blood Transfusion; Hemorrhage; Humans; Tranexamic Acid; Wounds and Inju

2022
Tranexamic acid for trauma in the USA: is prejudice a barrier to saving lives?
    Lancet (London, England), 2022, 04-30, Volume: 399, Issue:10336

    Topics: Antifibrinolytic Agents; Humans; Prejudice; Tranexamic Acid; Wounds and Injuries

2022
Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2 and CRASH-3) trials and UK trauma registry (Trauma and Audit Research Network) data.
    British journal of anaesthesia, 2022, Volume: 129, Issue:2

    Topics: Antifibrinolytic Agents; Female; Hemorrhage; Humans; Male; Registries; Tranexamic Acid; United Kingd

2022
Prehospital Tranexamic Acid in Major Pediatric Trauma Within a Physician-Led Emergency Medical Services System: A Multicenter Retrospective Study.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2022, 11-01, Volume: 23, Issue:11

    Topics: Adolescent; Antifibrinolytic Agents; Child; Emergency Medical Services; Female; Humans; Male; Physic

2022
Prehospital Tranexamic Acid in Major Pediatric Trauma: Only One Third of Severely Injured Children Receive It.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2023, 01-01, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Child; Emergency Medical Services; Humans; Tranexamic Acid; Wounds and Inju

2023
Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage.
    The journal of trauma and acute care surgery, 2023, 04-01, Volume: 94, Issue:4

    Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Humans; Resuscitation; Shock, Hemorrhagic

2023
Prehospital Tranexamic Acid Administration in Pediatric Trauma Patients: A Propensity-Matched Analysis of the Israeli Defense Forces Registry.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2023, 05-01, Volume: 24, Issue:5

    Topics: Adolescent; Antifibrinolytic Agents; Child; Cohort Studies; Female; Humans; Israel; Male; Registries

2023
Tranexamic Acid for Trauma Patients - More Lives to Save and Outcomes to Consider.
    The New England journal of medicine, 2023, Jul-13, Volume: 389, Issue:2

    Topics: Antifibrinolytic Agents; Humans; Tranexamic Acid; Wounds and Injuries

2023
Administration of tranexamic acid for victims of severe trauma within pre-hospital care ambulance services (PHCAS) in Malaysia.
    The Medical journal of Malaysia, 2019, Volume: 74, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulances; Antifibrinolytic Agents; Child; Drug Adminis

2019
Clinical relevance and practical assessment of fibrinolysis shutdown.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Blood Coagulation Disorders; Fibrin Fibrinogen Degrada

2020
Fibrinolytic shutdown diagnosed with rotational thromboelastometry represents a moderate form of coagulopathy associated with transfusion requirement and mortality: A retrospective analysis.
    European journal of anaesthesiology, 2020, Volume: 37, Issue:3

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Fibrinolysis; Humans; Retrospective Studies; T

2020
An Analysis of Adherence to Tactical Combat Casualty Care Guidelines for the Administration of Tranexamic Acid.
    The Journal of emergency medicine, 2019, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Female; Guideline Adherence; Hemo

2019
Early coagulation support protocol: A valid approach in real-life management of major trauma patients. Results from two Italian centres.
    Injury, 2019, Volume: 50, Issue:10

    Topics: Adult; Aged; Blood Coagulation; Blood Coagulation Disorders; Blood Transfusion; Clinical Protocols;

2019
Biological mechanisms and individual variation in fibrinolysis after major trauma.
    Emergency medicine journal : EMJ, 2020, Volume: 37, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Biomarkers; Decision Support Systems, Clinical; Emergency Service, H

2020
Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation.
    The western journal of emergency medicine, 2020, Feb-21, Volume: 21, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Drug Utilization; Female; Humans; Incidence; Injury Severity Score;

2020
Fibrinolysis and tranexamic acid: mechanistic principles.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Blood Coagulation; Fibrin; Fibrinolysin; Fibrinolysis; Hemorrhage; Humans;

2020
Influence of tranexamic acid on the complement system in trauma.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injuries

2020
Tranexamic acid and inflammation in trauma.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Inflammation; Tranexamic Acid; Wounds and Injuries

2020
Randomized controlled trials and Cochrane analyses versus precision-based medicine for tranexamic acid and viscoelastic testing in trauma.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Fibrinolysis; Humans; Incidence; Precision Med

2020
Computational model of tranexamic acid on urokinase mediated fibrinolysis.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: alpha 1-Antitrypsin; Antifibrinolytic Agents; Blood Coagulation; Blood Coagulation Disorders; Comput

2020
Early experience with transfusing low titer group O whole blood in the pre-hospital setting in Israel.
    Transfusion, 2020, Volume: 60 Suppl 3

    Topics: ABO Blood-Group System; Accidents, Traffic; Adolescent; Adult; Blood Pressure; Blood Transfusion; Ch

2020
Tranexamic acid is associated with reduced complement activation in trauma patients with hemorrhagic shock and hyperfibrinolysis on thromboelastography.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2020, Volume: 31, Issue:8

    Topics: Adult; Aged; Antifibrinolytic Agents; Complement Activation; Fibrinolysis; Humans; Male; Middle Aged

2020
Neck injuries - israel defense forces 20 years' experience.
    Injury, 2021, Volume: 52, Issue:2

    Topics: Humans; Israel; Military Personnel; Neck Injuries; Retrospective Studies; Tranexamic Acid; Wounds an

2021
Unjustified Administration in Liberal Use of Tranexamic Acid in Trauma Resuscitation.
    The Journal of surgical research, 2021, Volume: 258

    Topics: Adult; Aged; Antifibrinolytic Agents; Female; Humans; Inappropriate Prescribing; Male; Middle Aged;

2021
Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial.
    British journal of anaesthesia, 2021, Volume: 126, Issue:1

    Topics: Antifibrinolytic Agents; Female; Hemorrhage; Humans; Injections, Intramuscular; Male; Middle Aged; P

2021
Tranexamic acid and trauma coagulopathy: where are we now?
    British journal of anaesthesia, 2021, Volume: 126, Issue:1

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Hemorrhage; Humans; Tranexamic Acid; Wounds an

2021
The incidence of venous thromboembolic events in trauma patients after tranexamic acid administration: an EAST multicenter study.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Jan-01, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Incidence; Male; Middle Aged; Retrospect

2021
Plasmin thrombelastography rapidly identifies trauma patients at risk for massive transfusion, mortality, and hyperfibrinolysis: A diagnostic tool to resolve an international debate on tranexamic acid?
    The journal of trauma and acute care surgery, 2020, Volume: 89, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Biomarkers; Blood Coagulation Disorders; Blood Transfusion; Female;

2020
Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury?
    Shock (Augusta, Ga.), 2021, 01-01, Volume: 55, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Female; Humans; Injury Severity Score; Male; Middle Aged; Multiple O

2021
Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2021, Jan-06, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Emergency Medical Services; Female; Hemorrhage; Hu

2021
A Cross-sectional Survey on the Use of Tranexamic Acid in the Pre-hospital Setting.
    Rhode Island medical journal (2013), 2021, Mar-01, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Cross-Sectional Studies; Hemorrhage; Hospitals; Humans; Tranexamic Acid; Wo

2021
Use of tranexamic acid in trauma patients requiring massive transfusion protocol activation: a reassessment of prescribing behaviours in a major trauma centre in New Zealand.
    The New Zealand medical journal, 2021, 03-26, Volume: 134, Issue:1531

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Male; Middle Aged; New Zealand; P

2021
Does Liberal Prehospital and In-Hospital Tranexamic Acid Influence Outcome in Severely Injured Patients? A Prospective Cohort Study.
    World journal of surgery, 2021, Volume: 45, Issue:8

    Topics: Antifibrinolytic Agents; Female; Hospitals; Humans; Male; Prospective Studies; Tranexamic Acid; Trau

2021
After 800 Mtp Events, Mortality Due to Hemorrhagic Shock Remains High and Unchanged Despite Several In-Hospital Hemorrhage Control Advancements.
    Shock (Augusta, Ga.), 2021, 12-01, Volume: 56, Issue:1S

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemostatic Techniques; Humans; Louisiana;

2021
Early prehospital administration of tranexamic acid in hemorrhagic trauma is associated with increased survival as an independent variable.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2021, 08-01, Volume: 28, Issue:4

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Hemorrhage; Humans; Tranexamic Acid; Wounds and

2021
Early tranexamic acid administration ameliorates the endotheliopathy of trauma and shock in an in vitro model.
    The journal of trauma and acute care surgery, 2017, Volume: 82, Issue:6

    Topics: Angiopoietin-1; Angiopoietin-2; Antifibrinolytic Agents; Cell Adhesion Molecules; Endothelium, Vascu

2017
Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study.
    The western journal of emergency medicine, 2017, Volume: 18, Issue:4

    Topics: Adult; Antifibrinolytic Agents; California; Emergency Medical Services; Feasibility Studies; Female;

2017
Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study.
    The western journal of emergency medicine, 2017, Volume: 18, Issue:4

    Topics: Adult; Antifibrinolytic Agents; California; Emergency Medical Services; Feasibility Studies; Female;

2017
Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study.
    The western journal of emergency medicine, 2017, Volume: 18, Issue:4

    Topics: Adult; Antifibrinolytic Agents; California; Emergency Medical Services; Feasibility Studies; Female;

2017
Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study.
    The western journal of emergency medicine, 2017, Volume: 18, Issue:4

    Topics: Adult; Antifibrinolytic Agents; California; Emergency Medical Services; Feasibility Studies; Female;

2017
Effect of team training on efficiency of trauma care in a Chinese hospital.
    The Journal of international medical research, 2018, Volume: 46, Issue:1

    Topics: Adult; China; Emergency Service, Hospital; Female; Hematologic Tests; Hemostasis; Hospitals; Humans;

2018
Tranexamic acid is associated with increased mortality in patients with physiological fibrinolysis.
    The Journal of surgical research, 2017, Volume: 220

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Colorado; Female; Fibrinolysis; Humans; Male; Mid

2017
Military use of tranexamic acid in combat trauma: Does it matter?
    The journal of trauma and acute care surgery, 2017, Volume: 83, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Female; Humans; Male; Military Medicine; Retrospective Studies; Surv

2017
Endotheliopathy of Trauma is an on-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational Study.
    Shock (Augusta, Ga.), 2018, Volume: 49, Issue:4

    Topics: Adult; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Prospective

2018
Civilian and military doctors' knowledge of tranexamic acid (TXA) use in major trauma: a comparison study.
    Journal of the Royal Army Medical Corps, 2018, Volume: 164, Issue:3

    Topics: Antifibrinolytic Agents; Health Knowledge, Attitudes, Practice; Humans; Military Medicine; Physician

2018
Evaluation of Military Use of Tranexamic Acid and Associated Thromboembolic Events.
    JAMA surgery, 2018, 02-01, Volume: 153, Issue:2

    Topics: Abdominal Injuries; Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Guideline Adherence;

2018
Increased risk of fibrinolysis shutdown among severely injured trauma patients receiving tranexamic acid.
    The journal of trauma and acute care surgery, 2018, Volume: 84, Issue:3

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Dose-Response Relationship, Drug; Female; Fibr

2018
Left atrial thrombi following tranexamic acid in a bleeding trauma patient-A word of caution.
    Journal of cardiac surgery, 2018, Volume: 33, Issue:2

    Topics: Adult; Anticoagulants; Antifibrinolytic Agents; Female; Heart Atria; Heart Diseases; Hemorrhage; Hep

2018
Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.
    Experimental animals, 2018, Jul-30, Volume: 67, Issue:3

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models,

2018
Optimisation of the dosage of tranexamic acid in trauma patients with population pharmacokinetic analysis.
    Anaesthesia, 2018, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Brain Injuries, Traumatic; Drug

2018
Tranexamic acid in severe trauma patients managed in a mature trauma care system.
    The journal of trauma and acute care surgery, 2018, Volume: 84, Issue:6S Suppl 1

    Topics: Adult; Antifibrinolytic Agents; Female; Hemodynamics; Hospital Mortality; Humans; Male; Middle Aged;

2018
Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy.
    Annals of biomedical engineering, 2018, Volume: 46, Issue:8

    Topics: Acute Disease; Disseminated Intravascular Coagulation; Fibrinolysis; Humans; Models, Cardiovascular;

2018
Evaluation of tranexamic acid in trauma patients: A retrospective quantitative analysis.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; British Columbia; Female; Hemorrhage; Hospital Mo

2019
Severely injured trauma patients with admission hyperfibrinolysis: Is there a role of tranexamic acid? Findings from the PROPPR trial.
    The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Female; Fibrinolysis; Hemorrhage; Hemostasis; Humans; Injury Severit

2018
Safety of Tranexamic Acid During Pediatric Trauma: A Nationwide Database Study.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:12

    Topics: Acute Kidney Injury; Antifibrinolytic Agents; Case-Control Studies; Child; Child, Preschool; Databas

2018
Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Injury Severity Score

2019
Use of tranexamic acid in trauma patients requiring massive transfusion protocol activation: an audit in a major trauma centre in New Zealand.
    The New Zealand medical journal, 2018, 10-05, Volume: 131, Issue:1483

    Topics: Adult; Antifibrinolytic Agents; Blood Component Transfusion; Female; Hemorrhage; Humans; Male; Medic

2018
Traumatic coagulopathies.
    Medicina intensiva, 2019, Volume: 43, Issue:8

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Fibrinolysis; Forecasting; Humans; Resuscitati

2019
Tranexamic Acid in Civilian Trauma Care in the California Prehospital Antifibrinolytic Therapy Study.
    The western journal of emergency medicine, 2018, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Antifibrinolytic Agents; California; Emergency Medical Services; Female; Glasgow

2018
Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury.
    The Journal of surgical research, 2019, Volume: 233

    Topics: Adult; Air Ambulances; Antifibrinolytic Agents; Blood Transfusion; Emergency Service, Hospital; Fema

2019
Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study.
    Emergency medicine journal : EMJ, 2019, Volume: 36, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Cross-Sectional Studies; England; Female; Hemorrhage; Humans; Longit

2019
Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Blood Coagulation; Complement C5a; Female;

2019
Towards patient-specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry.
    Journal of thrombosis and haemostasis : JTH, 2019, Volume: 17, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Clinical Decision-Making; Decision Support Techniques; Erythrocyte T

2019
Effects of modification of trauma bleeding management: A before and after study.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Coagulants; Controlled Before-After Studies; Eryt

2019
Does Tranexamic Acid Improve Clot Strength in Severely Injured Patients Who Have Elevated Fibrin Degradation Products and Low Fibrinolytic Activity, Measured by Thrombelastography?
    Journal of the American College of Surgeons, 2019, Volume: 229, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Biomarkers; Female; Fibrin Clot Lysis Time; Fibrin Fibrinogen Degrad

2019
Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Animals; DNA Damage; DNA, Mitochondrial; Endothelial Cells; Granulocytes; Hemorrhage; Humans; Mice;

2019
Prehospital administration of tranexamic acid in trauma patients: A 1:1 matched comparative study from a level 1 trauma center.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:2

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Emergency Medical Services;

2020
Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model.
    Journal of thrombosis and haemostasis : JTH, 2019, Volume: 17, Issue:10

    Topics: Animals; Antifibrinolytic Agents; Blood Platelets; Disease Models, Animal; Fibrinogen; Hemorrhage; H

2019
Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process.
    The journal of trauma and acute care surgery, 2019, Volume: 87, Issue:4

    Topics: Antifibrinolytic Agents; Blood Transfusion; Child; Consensus; Delphi Technique; Hemorrhage; Humans;

2019
Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process.
    The journal of trauma and acute care surgery, 2019, Volume: 87, Issue:4

    Topics: Antifibrinolytic Agents; Blood Transfusion; Child; Consensus; Delphi Technique; Hemorrhage; Humans;

2019
Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process.
    The journal of trauma and acute care surgery, 2019, Volume: 87, Issue:4

    Topics: Antifibrinolytic Agents; Blood Transfusion; Child; Consensus; Delphi Technique; Hemorrhage; Humans;

2019
Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process.
    The journal of trauma and acute care surgery, 2019, Volume: 87, Issue:4

    Topics: Antifibrinolytic Agents; Blood Transfusion; Child; Consensus; Delphi Technique; Hemorrhage; Humans;

2019
Influence of resuscitation fluids, fresh frozen plasma and antifibrinolytics on fibrinolysis in a thrombelastography-based, in-vitro, whole-blood model.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation Disorders; Colloids; Crystalloid Solut

2013
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study.
    JAMA surgery, 2013, Volume: 148, Issue:3

    Topics: Afghanistan; Antifibrinolytic Agents; Cohort Studies; Drug Therapy, Combination; Factor VIII; Female

2013
PURLs: Trauma care--don't delay with TXA.
    The Journal of family practice, 2013, Volume: 62, Issue:5

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injuries

2013
Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities.
    Shock (Augusta, Ga.), 2013, Volume: 40, Issue:2

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injuries

2013
Reducing trauma deaths in the UK.
    Lancet (London, England), 2013, Jul-20, Volume: 382, Issue:9888

    Topics: Antifibrinolytic Agents; Clinical Protocols; Emergency Service, Hospital; Hemorrhage; Humans; Tranex

2013
Tranexamic acid in trauma: we need stronger global health policy.
    BMJ (Clinical research ed.), 2013, Jul-23, Volume: 347

    Topics: Antifibrinolytic Agents; Global Health; Health Policy; Hemorrhage; Humans; Multicenter Studies as To

2013
Trauma and tranexamic acid.
    The Medical journal of Australia, 2013, Sep-02, Volume: 199, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Thrombosis; Tranexamic Acid; Woun

2013
Is viscoelastic evidence of hyperfibrinolysis the ideal indicator for tranexamic acid administration in trauma?
    The journal of trauma and acute care surgery, 2013, Volume: 75, Issue:4

    Topics: Antifibrinolytic Agents; Humans; Tranexamic Acid; Wounds and Injuries

2013
Re: Is viscoelastic evidence of hyperfibrinolysis the ideal indicator for tranexamic acid administration in trauma?
    The journal of trauma and acute care surgery, 2013, Volume: 75, Issue:4

    Topics: Antifibrinolytic Agents; Humans; Tranexamic Acid; Wounds and Injuries

2013
Fibrinogen depletion after plasma-dilution: impairment of proteolytic resistance and reversal via clotting factor concentrates.
    Thrombosis and haemostasis, 2014, Mar-03, Volume: 111, Issue:3

    Topics: Blood Coagulation; Factor XIII; Fibrinogen; Fibrinolysin; Fibrinolysis; Hemodilution; Hemorrhage; Hu

2014
The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis.
    The journal of trauma and acute care surgery, 2013, Volume: 75, Issue:6

    Topics: Acidosis; Animals; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors;

2013
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Tranexamic acid at the point of injury: the Israeli combined civilian and military experience.
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:3 Suppl 2

    Topics: Adult; Antifibrinolytic Agents; Clinical Protocols; Emergency Medical Services; Female; Hemorrhage;

2014
Tranexamic acid administration to pediatric trauma patients in a combat setting: the pediatric trauma and tranexamic acid study (PED-TRAX).
    The journal of trauma and acute care surgery, 2014, Volume: 77, Issue:6

    Topics: Afghan Campaign 2001-; Antifibrinolytic Agents; Blood Transfusion; Child; Female; Glasgow Coma Scale

2014
The benefits of TXA. Implementing tranexamic acid for trauma patients will result in decreased mortality.
    EMS world, 2015, Volume: 44, Issue:3

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Humans; Tranexamic Acid; Wounds and Injuries

2015
Addition of tranexamic acid to a traumatic injury massive transfusion protocol.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Jun-15, Volume: 72, Issue:12

    Topics: Academic Medical Centers; Adolescent; Adult; Antifibrinolytic Agents; Boston; Cooperative Behavior;

2015
Use of Tranexamic Acid in Bleeding Combat Casualties.
    Military medicine, 2015, Volume: 180, Issue:8

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Military Personnel; Tranexamic Acid; Wounds and Injurie

2015
Tranexamic acid in major trauma: implementation and evaluation across South West England.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2017, Volume: 24, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Emergency Medical Services; Emergency Service, Hospital; Engla

2017
Time since injury is the major factor in preventing tranexamic acid use in the trauma setting: An observational cohort study from a major trauma centre in a middle-income country.
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2015, Oct-08, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Cohort Studies; Drug Administra

2015
Tranexamic acid in the trauma patient.
    Nursing, 2016, Volume: 46, Issue:2

    Topics: Accidents, Traffic; Adult; Antifibrinolytic Agents; Emergency Nursing; Emergency Service, Hospital;

2016
Tranexamic acid in the trauma patient.
    Nursing, 2016, Volume: 46, Issue:2

    Topics: Accidents, Traffic; Adult; Antifibrinolytic Agents; Emergency Nursing; Emergency Service, Hospital;

2016
Tranexamic acid in the trauma patient.
    Nursing, 2016, Volume: 46, Issue:2

    Topics: Accidents, Traffic; Adult; Antifibrinolytic Agents; Emergency Nursing; Emergency Service, Hospital;

2016
Tranexamic acid in the trauma patient.
    Nursing, 2016, Volume: 46, Issue:2

    Topics: Accidents, Traffic; Adult; Antifibrinolytic Agents; Emergency Nursing; Emergency Service, Hospital;

2016
Tranexamic acid in life-threatening military injury and the associated risk of infective complications.
    The British journal of surgery, 2016, Volume: 103, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans;

2016
Tranexamic Acid Use in United States Children's Hospitals.
    The Journal of emergency medicine, 2016, Volume: 50, Issue:6

    Topics: Antifibrinolytic Agents; Child; Child, Preschool; Cohort Studies; Female; Hospitals, Pediatric; Huma

2016
Rationale for the selective administration of tranexamic acid to inhibit fibrinolysis in the severely injured patient.
    Transfusion, 2016, Volume: 56 Suppl 2

    Topics: Animals; Antifibrinolytic Agents; Fibrin; Fibrinolysis; Humans; Phenotype; Plasminogen; Plasminogen

2016
Prehospital administration of tranexamic acid in trauma patients.
    Critical care (London, England), 2016, May-12, Volume: 20, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Cohort Studies; Female; Hospital Mortality; Humans; Male; Middle Age

2016
[Uncritical use of tranexamic acid in trauma patients : Do no further harm!]
    Der Unfallchirurg, 2016, Volume: 119, Issue:11

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Evidence-Based Medicine; Hemorrhage; Humans; Tr

2016
Compatibility of Hydroxyethyl Starch and Tranexamic Acid for Battlefield Co-Administration.
    Military medicine, 2016, Volume: 181, Issue:10

    Topics: Drug Therapy, Combination; Fluid Therapy; Hemorrhage; Humans; Hydroxyethyl Starch Derivatives; Trane

2016
Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy.
    The British journal of surgery, 2017, Volume: 104, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfus

2017
[Tranexamic acid in the German emergency medical service : A national survey].
    Der Anaesthesist, 2017, Volume: 66, Issue:4

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Germany; Guideline Adherence; Guidelines as Top

2017
Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma.
    The journal of trauma and acute care surgery, 2017, Volume: 82, Issue:3

    Topics: Antifibrinolytic Agents; Blood Cell Count; Blood Transfusion; Factor VIIa; Hemorrhage; Humans; Recom

2017
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:1

    Topics: Afibrinogenemia; Antifibrinolytic Agents; Fibrinogen; Fibrinolysis; Hemorrhage; Hemostasis; Humans;

2010
Antifibrinolytic therapy: new data and new concepts.
    Lancet (London, England), 2010, Jul-03, Volume: 376, Issue:9734

    Topics: Antifibrinolytic Agents; Fibrinolysin; Hemorrhage; Hemostasis; Humans; Tranexamic Acid; Wounds and I

2010
Tranexamic acid for trauma.
    Lancet (London, England), 2010, Sep-25, Volume: 376, Issue:9746

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Tranexamic Acid;

2010
Tranexamic acid for trauma.
    Lancet (London, England), 2010, Sep-25, Volume: 376, Issue:9746

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Nervous System Diseases; Randomized Controlled Trials a

2010
Tranexamic acid for trauma.
    Lancet (London, England), 2010, Sep-25, Volume: 376, Issue:9746

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Selection Bias;

2010
Hemostatic agents: which is better?
    The Journal of trauma, 2010, Volume: 69, Issue:6

    Topics: Antifibrinolytic Agents; Blood Transfusion; Factor VIIa; France; Hemostatics; Humans; Military Medic

2010
Effect of consent rituals on mortality in emergency care research.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Antifibrinolytic Agents; Emergency Treatment; Hemorrhage; Humans; Informed Consent; Logistic Models;

2011
Tranexamic acid for trauma.
    Lancet (London, England), 2011, Mar-26, Volume: 377, Issue:9771

    Topics: Antifibrinolytic Agents; Emergency Medical Services; Emergency Service, Hospital; Hemorrhage; Humans

2011
The use of fresh whole blood transfusions by the SOF medic for hemostatic resuscitation in the austere environment.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2010,Fall, Volume: 10, Issue:4

    Topics: Blood Transfusion; Emergency Medical Services; Hemorrhage; Hemostatic Techniques; Hemostatics; Human

2010
[Clinical trials in surgery - health care research of the future?].
    Zentralblatt fur Chirurgie, 2011, Volume: 136, Issue:2

    Topics: Antifibrinolytic Agents; Clinical Trials as Topic; Forecasting; Germany; Health Services Research; H

2011
[Hyperfibrinolysis as the cause of haemorrhage and increased mortality in trauma patients].
    Ugeskrift for laeger, 2011, May-02, Volume: 173, Issue:18

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfusion; Fibrinolysis; Hemorrhage; H

2011
Thousands of lives could be saved using tranexamic acid for patients with bleeding trauma.
    Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention, 2011, Volume: 17, Issue:3

    Topics: Antifibrinolytic Agents; Female; Hemorrhage; Humans; Male; Review Literature as Topic; Tranexamic Ac

2011
Advances in trauma care.
    The American journal of nursing, 2011, Volume: 111, Issue:7

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Child; Child, Preschool; Emergency Medical Services; Hem

2011
Consent in emergency care research.
    Lancet (London, England), 2011, Jul-02, Volume: 378, Issue:9785

    Topics: Antifibrinolytic Agents; Biomedical Research; Emergency Service, Hospital; Hemorrhage; Humans; Infor

2011
Early administration of tranexamic acid in trauma patients.
    Lancet (London, England), 2011, Jul-02, Volume: 378, Issue:9785

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Time Factors; Tr

2011
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.
    Archives of surgery (Chicago, Ill. : 1960), 2012, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Afghan Campaign 2001-; Antifibrinolytic Agents; Blast Injuries; Blood Transfusion

2012
Tranexamic acid--a recipe for saving lives in traumatic bleeding.
    International journal of epidemiology, 2011, Volume: 40, Issue:5

    Topics: Antifibrinolytic Agents; Female; Hemorrhage; Humans; Male; Menorrhagia; Randomized Controlled Trials

2011
CRASH-2 goes viral.
    Lancet (London, England), 2011, Nov-19, Volume: 378, Issue:9805

    Topics: Adult; Antifibrinolytic Agents; Cost-Benefit Analysis; Hemorrhage; Humans; Information Dissemination

2011
[Secondary prevention in trauma pathology. Is there an influence of commercial interests on evidence implementation?].
    Medicina clinica, 2012, Feb-04, Volume: 138, Issue:2

    Topics: Accident Prevention; Commerce; Decontamination; Diffusion of Innovation; Drug Utilization; Evidence-

2012
Tranexamic acid--a recipe for saving lives in traumatic bleeding.
    Journal of primary health care, 2011, Dec-01, Volume: 3, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Drug Administration Schedule; Follow-Up Studies; Hemorrhage; Humans;

2011
[Emergency medicine: updates 2011].
    Revue medicale suisse, 2012, Jan-11, Volume: 8, Issue:323

    Topics: Acute Disease; Ambulatory Care; Anisoles; Antifibrinolytic Agents; Appendicitis; Atrial Fibrillation

2012
Tranexamic acid: less bleeding and less thrombosis?
    Critical care (London, England), 2012, Jun-29, Volume: 16, Issue:3

    Topics: Antifibrinolytic Agents; Factor V; Factor VIII; Fibrinolysin; Hemorrhage; Humans; Plasminogen; Plate

2012
Administer tranexamic acid early to injured patients at risk of substantial bleeding.
    BMJ (Clinical research ed.), 2012, Nov-19, Volume: 345

    Topics: Antifibrinolytic Agents; Early Medical Intervention; Hemorrhage; Humans; Risk Factors; Tranexamic Ac

2012
A promise to save 100,000 trauma patients.
    Lancet (London, England), 2012, Dec-15, Volume: 380, Issue:9859

    Topics: Antifibrinolytic Agents; Exsanguination; Humans; Tranexamic Acid; Wounds and Injuries

2012
Recombinant tissue-type plasminogen activator-evoked hyperfibrinolysis is enhanced by acidosis and inhibited by hypothermia but still can be blocked by tranexamic acid.
    The journal of trauma and acute care surgery, 2013, Volume: 74, Issue:2

    Topics: Acidosis; Adult; Blood Coagulation; Blood Coagulation Disorders; Female; Fibrinolytic Agents; Humans

2013
Tranexamic acid looks promising during emergency surgery.
    BMJ (Clinical research ed.), 2013, Feb-06, Volume: 346

    Topics: Adult; Antifibrinolytic Agents; Emergencies; Humans; Stroke; Tranexamic Acid; Wounds and Injuries

2013
Antifibrinolytic agents in traumatic hemorrhage: a large scale randomized controlled trial is needed.
    Croatian medical journal, 2005, Volume: 46, Issue:1

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Tranexamic Acid;

2005
[CRASH-2: the Clinical Randomization of an Antifibrinolytic in Significant Haemorrhage trial].
    Revista espanola de anestesiologia y reanimacion, 2005, Volume: 52, Issue:10

    Topics: Adult; Antifibrinolytic Agents; Child; Hemorrhage; Humans; Multicenter Studies as Topic; Patient Sel

2005
Trial of drug for trauma patients includes victims of Iraqi violence.
    BMJ (Clinical research ed.), 2006, May-27, Volume: 332, Issue:7552

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Tranexamic Acid;

2006
Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage.
    Resuscitation, 2006, Volume: 70, Issue:1

    Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Aprotinin; Deamino Arginine Vasopressin; Diseas

2006
Influence of tranexamic acid on lung tissue fibrinolysis after trauma.
    Bibliotheca anatomica, 1977, Issue:16 Pt 2

    Topics: Animals; Cyclohexanecarboxylic Acids; Fibrinolysis; Pulmonary Circulation; Rats; Tranexamic Acid; Wo

1977
Fibrinolysis in the lung. Experimental studies on tissue localization and on the response to drug induced antifibrinolysis and to trauma.
    Acta chirurgica Scandinavica. Supplementum, 1975, Volume: 458

    Topics: Animals; Fibrinolysis; Hydrocortisone; Lung; Perfusion; Plasminogen Activators; Rats; Rats, Inbred S

1975