tranexamic acid has been researched along with Wounds, Penetrating in 10 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Wounds, Penetrating: Wounds caused by objects penetrating the skin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients." | 9.24 | Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. ( Edwards, P; Joshi, M; Ker, K; Mahmood, A; Prieto, D; Roberts, I; Shakur, H, 2017) |
| " The CRASH-2 trial aimed to determine the effect of the early administration of tranexamic acid on death and transfusion requirement in bleeding trauma patients." | 9.17 | The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. ( Balogun, E; Barnetson, L; Cairns, J; Coats, T; Cook, L; Guerriero, C; Hunt, B; Kawahara, T; Perel, P; Prieto-Merino, D; Ramos, M; Roberts, I; Shakur, H, 2013) |
| "The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients." | 5.24 | Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. ( Edwards, P; Joshi, M; Ker, K; Mahmood, A; Prieto, D; Roberts, I; Shakur, H, 2017) |
| " The CRASH-2 trial aimed to determine the effect of the early administration of tranexamic acid on death and transfusion requirement in bleeding trauma patients." | 5.17 | The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. ( Balogun, E; Barnetson, L; Cairns, J; Coats, T; Cook, L; Guerriero, C; Hunt, B; Kawahara, T; Perel, P; Prieto-Merino, D; Ramos, M; Roberts, I; Shakur, H, 2013) |
| "The CRASH-2 trial demonstrated that tranexamic acid (TXA) in adults with significant traumatic hemorrhage safely reduces mortality." | 3.96 | Mortality and Complication Rates in Adult Trauma Patients Receiving Tranexamic Acid: A Single-center Experience in the Post-CRASH-2 Era. ( Benipal, S; Erramouspe, PJ; Galante, JM; García-Pintos, MF; Manoukian, MAC; Nishijima, D; Santamarina, JL; Shawagga, HG; Vo, LL, 2020) |
| "Accumulating evidence established the benefit of tranexamic acid (TXA) for traumatic bleeding in the hospital setting." | 3.80 | Tranexamic acid at the point of injury: the Israeli combined civilian and military experience. ( Abramovich, A; Benov, A; Gendler, S; Glassberg, E; Nadler, R; Strugo, R, 2014) |
| " Standard adult dosing of TXA was used in all patients." | 1.40 | Tranexamic acid administration to pediatric trauma patients in a combat setting: the pediatric trauma and tranexamic acid study (PED-TRAX). ( Eckert, MJ; Izenberg, S; Martin, MJ; Nelson, DW; Tyner, SD; Wertin, TM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erramouspe, PJ | 1 |
| García-Pintos, MF | 1 |
| Benipal, S | 1 |
| Manoukian, MAC | 1 |
| Santamarina, JL | 1 |
| Shawagga, HG | 1 |
| Vo, LL | 1 |
| Galante, JM | 1 |
| Nishijima, D | 1 |
| Hoffmann, C | 1 |
| Goudard, Y | 1 |
| Falzone, E | 1 |
| Leclerc, T | 1 |
| Planchet, M | 1 |
| Cazes, N | 1 |
| Pons, F | 1 |
| Lenoir, B | 1 |
| Debien, B | 1 |
| Roberts, I | 2 |
| Shakur, H | 2 |
| Coats, T | 1 |
| Hunt, B | 1 |
| Balogun, E | 1 |
| Barnetson, L | 1 |
| Cook, L | 1 |
| Kawahara, T | 1 |
| Perel, P | 1 |
| Prieto-Merino, D | 1 |
| Ramos, M | 1 |
| Cairns, J | 1 |
| Guerriero, C | 1 |
| Goodloe, JM | 1 |
| Howerton, DS | 1 |
| McAnallen, D | 1 |
| Reed, H | 1 |
| Lipsky, AM | 1 |
| Abramovich, A | 2 |
| Nadler, R | 2 |
| Feinstein, U | 1 |
| Shaked, G | 1 |
| Kreiss, Y | 1 |
| Glassberg, E | 2 |
| Gendler, S | 1 |
| Benov, A | 1 |
| Strugo, R | 1 |
| Eckert, MJ | 1 |
| Wertin, TM | 1 |
| Tyner, SD | 1 |
| Nelson, DW | 1 |
| Izenberg, S | 1 |
| Martin, MJ | 1 |
| Kluj, P | 1 |
| Aleksandrowicz, D | 1 |
| Machała, W | 1 |
| Gaszyński, T | 1 |
| Edwards, P | 1 |
| Prieto, D | 1 |
| Joshi, M | 1 |
| Mahmood, A | 1 |
| Ker, K | 1 |
| Barrie, J | 1 |
| Jamdar, S | 1 |
| Iniguez, MF | 1 |
| Bouamra, O | 1 |
| Jenks, T | 1 |
| Lecky, F | 1 |
| O'Reilly, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339] | Phase 2 | 0 participants (Actual) | Interventional | 2022-03-31 | Withdrawn (stopped due to Challenges in recruitment) | ||
| Randomized Study on the Topical Application of Tranexamic Acid to Wound Bed for Hemostasis in the Setting Granulating Wounds Following Mohs Micrographic Surgery[NCT04541303] | Early Phase 1 | 62 participants (Anticipated) | Interventional | 2020-10-08 | Recruiting | ||
| The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty[NCT03795649] | 80 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | |||
| A Large Randomised Placebo Controlled Trial Among Trauma Patients With, or at Risk of, Significant Haemorrhage, of the Effects of Antifibrinolytic Treatment on Death and Transfusion Requirement[NCT00375258] | Phase 3 | 20,211 participants (Actual) | Interventional | 2005-05-31 | Completed | ||
| Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880] | Phase 4 | 25 participants (Actual) | Interventional | 2020-09-10 | Active, not recruiting | ||
| Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973] | Phase 3 | 220 participants (Actual) | Interventional | 2018-12-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for tranexamic acid and Wounds, Penetrating
| Article | Year |
|---|---|
[Management of penetrating abdominal trauma: what we need to know?].
Topics: Abdominal Injuries; Anesthesia; Antifibrinolytic Agents; Emergency Medical Services; France; Humans; | 2013 |
TXA: a difference-maker for trauma patients.
Topics: Antifibrinolytic Agents; Decision Making; Emergency Treatment; Hemorrhage; Humans; Tranexamic Acid; | 2013 |
[Advanced methods of prehospital bleeding management based on the experience and standards of tactical medicine].
Topics: Abdominal Injuries; Amputation, Traumatic; Antifibrinolytic Agents; Emergency Medical Services; Hemo | 2015 |
2 trials available for tranexamic acid and Wounds, Penetrating
5 other studies available for tranexamic acid and Wounds, Penetrating
| Article | Year |
|---|---|
Mortality and Complication Rates in Adult Trauma Patients Receiving Tranexamic Acid: A Single-center Experience in the Post-CRASH-2 Era.
Topics: Adult; Aged; Antifibrinolytic Agents; Female; Hemorrhage; Humans; Injury Severity Score; Male; Middl | 2020 |
Tranexamic acid in the prehospital setting: Israel Defense Forces' initial experience.
Topics: Adult; Antifibrinolytic Agents; Clinical Protocols; Emergency Medical Services; Female; Hemorrhage; | 2014 |
Tranexamic acid at the point of injury: the Israeli combined civilian and military experience.
Topics: Adult; Antifibrinolytic Agents; Clinical Protocols; Emergency Medical Services; Female; Hemorrhage; | 2014 |
Tranexamic acid administration to pediatric trauma patients in a combat setting: the pediatric trauma and tranexamic acid study (PED-TRAX).
Topics: Afghan Campaign 2001-; Antifibrinolytic Agents; Blood Transfusion; Child; Female; Glasgow Coma Scale | 2014 |
Improved outcomes for hepatic trauma in England and Wales over a decade of trauma and hepatobiliary surgery centralisation.
Topics: Adult; Antifibrinolytic Agents; Digestive System Surgical Procedures; Emergency Medicine; England; F | 2018 |