Page last updated: 2024-11-05

tranexamic acid and Spinal Neoplasms

tranexamic acid has been researched along with Spinal Neoplasms in 5 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Spinal Neoplasms: New abnormal growth of tissue in the SPINE.

Research Excerpts

ExcerptRelevanceReference
"The primary outcome was postoperative blood loss, and the secondary outcomes were postoperative PRC transfusion and complications."3.11Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial. ( Atthakomol, P; Maethungkul, R; Murakami, H; Phanphaisarn, A; Phinyo, P; Sangsin, A, 2022)
"Patients suffered from acute spinal cord compression caused by spinal tumor manifestation (n = 5), empyema (n = 4), degenerative spinal stenosis (n = 1), hematoma (n = 1), and vertebral body fracture/dislocation (n = 2)."1.51Management of Spinal Emergencies in Patients on Direct Oral Anticoagulants. ( Beynon, C; Gumbinger, C; Olivares, A; Unterberg, AW; Younsi, A; Zweckberger, K, 2019)
"Tranexamic acid was used arbitrarily in 36 of them, while the other 47 did not receive TXA."1.51Blood loss and perioperative transfusions related to surgery for spinal tumors. Relevance of tranexamic acid. ( Damade, C; Foulongne, E; Gauthé, R; Gilard, V; Ould-Slimane, M; Tesson, G; Vigny, S, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Maethungkul, R1
Atthakomol, P1
Phinyo, P1
Phanphaisarn, A1
Murakami, H1
Sangsin, A1
Beynon, C1
Olivares, A1
Gumbinger, C1
Younsi, A1
Zweckberger, K1
Unterberg, AW1
Damade, C1
Tesson, G1
Gilard, V1
Vigny, S1
Foulongne, E1
Gauthé, R1
Ould-Slimane, M1
Bednar, DA1
Bednar, VA1
Chaudhary, A1
Farrokhyar, F1
Farroukhyar, F1
Cravens, GT1
Brown, MJ1
Brown, DR1
Wass, CT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Topical Tranexamic Acid in Total Hip Arthroplasty[NCT01866943]Phase 241 participants (Actual)Interventional2011-11-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Estimated Blood Loss

Estimated Blood Loss defined as Pre Op Hgb mins the Post Op Day two Hgb. (NCT01866943)
Timeframe: Pre Op, Post Op Day 2

InterventionHemoglobin (grams/deciliter) (Mean)
Baseline Population2.93

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 2 week

Interventionunits on a scale (Mean)
All Study Participants65.76

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 6 week

Interventionunits on a scale (Mean)
All Study Participants81.77

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: Preoperative

Interventionunits on a scale (Mean)
All Study Participants58.34

Mid Thigh Circumference

Measurement of the thigh at the half way point between the prominence of the greater trochanter and the lateral epicondyle of the femur. No data recorded at 2 weeks or 6 weeks for this study population. (NCT01866943)
Timeframe: Pre Op

Interventioncentimeters (Mean)
Baseline Population52.99

Trials

1 trial available for tranexamic acid and Spinal Neoplasms

ArticleYear
Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial.
    Spine, 2022, Feb-01, Volume: 47, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorr

2022

Other Studies

4 other studies available for tranexamic acid and Spinal Neoplasms

ArticleYear
Management of Spinal Emergencies in Patients on Direct Oral Anticoagulants.
    World neurosurgery, 2019, Volume: 131

    Topics: Acute Disease; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Blood Coagulation Factors; Bl

2019
Blood loss and perioperative transfusions related to surgery for spinal tumors. Relevance of tranexamic acid.
    Neuro-Chirurgie, 2019, Volume: 65, Issue:6

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Decompression, Surgic

2019
Tranexamic acid for hemostasis in the surgical treatment of metastatic tumors of the spine.
    Spine, 2006, Apr-15, Volume: 31, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Female; Hemostasis, Surgical; Humans; Male; Middle Aged; Retrospecti

2006
Antifibrinolytic therapy use to mitigate blood loss during staged complex major spine surgery: Postoperative visual color changes after tranexamic acid administration.
    Anesthesiology, 2006, Volume: 105, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Chordoma; Color Perception; Color Vision Defects; Hum

2006