tranexamic acid has been researched along with Scoliosis in 48 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Scoliosis: An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tranexamic acid (TXA) has been widely used in orthopedic surgery, but its efficacy in adolescent scoliosis (AS) surgery remains unclear in the literature." | 9.41 | Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis. ( Chen, K; Gao, Q; Masood, U; Song, Y; Wang, L; Yang, H; Zeng, Z, 2023) |
| "Tranexamic acid (TXA) is widely used in surgery for adolescent idiopathic scoliosis (AIS) and has been proved to be efficacious in reducing intraoperative blood loss (IBL) and the transfusion rate." | 9.41 | The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial. ( Liu, LM; Song, YM; Wang, L; Wang, LN; Xiu, P; Yang, X; Zhang, Z; Zhou, ZJ, 2021) |
| "The objective of this study is to determine the efficacy of high-dose versus low-dose tranexamic acid (TXA) in adolescent idiopathic scoliosis (AIS) corrective surgery." | 9.41 | Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery. ( Chan, CYW; Chiu, CK; Hasan, MS; Kwan, MK; Ng, CC; Yunus, SN, 2021) |
| "To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TXA alone." | 9.41 | Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial. ( Dong, Y; Li, Q; Liang, J; Shen, J; Tong, B; Zhao, H, 2021) |
| "We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn." | 9.24 | Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery. ( Endo, N; Kohno, T; Ohashi, M; Ohashi, N, 2017) |
| "This study aimed to evaluate the efficacy and safety of using high-dose intravenous tranexamic acid (TXA) to reduce blood loss in idiopathic scoliosis surgery." | 9.12 | The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis. ( Chen, JC; Lin, L; Na, XQ; Qu, QC; Ruan, TY; Shrestha, IK; Si, YY; Tan, M; Tao, JP, 2021) |
| "Intraoperative administration of tranexamic acid significantly reduces blood loss during spinal surgery in children with scoliosis." | 9.11 | Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. ( Bacsik, J; Brustowicz, RM; Sethna, NF; Shapiro, F; Sullivan, LJ; Zurakowski, D, 2005) |
| "The administration of prophylactic tranexamic acid in patients with scoliosis who are undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements." | 9.09 | A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. ( Barrowman, NJ; Hall, L; Murto, K; Neilipovitz, DT; Splinter, WM, 2001) |
| "To evaluate the efficacy and safety of tranexamic acid (TXA) in patients with adolescent idiopathic scoliosis undergoing corrective surgery." | 9.01 | The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis. ( Cao, K; Lin, N; Lu, H; Wang, B; Zhong, J; Zhou, X, 2019) |
| "The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of tranexamic acid (TXA) versus placebo after a scoliosis surgery." | 8.95 | Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis. ( Xu, BS; Yuan, QM; Zhao, ZH, 2017) |
| "The utility of tranexamic acid (TXA) in patients with Marfan syndrome (MFS) is uncertain given associated aberrations within the vasculature and clotting cascade." | 8.12 | Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome. ( Ikwuezunma, IA; Margalit, A; Sponseller, PD, 2022) |
| "The administration of tranexamic acid (TXA) has been shown to be beneficial in reducing blood loss during surgery for adolescent idiopathic scoliosis (AIS), but optimal dosing has yet to be defined." | 8.12 | High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis. ( Bacon, A; Javidan, Y; Klineberg, E; Roberto, R; Stondell, C; Tafoya, S; Taylor, SL; Tumber, S, 2022) |
| "Intravenous tranexamic acid (TXA) has been administered to reduce intraoperative blood loss in scoliosis surgery." | 8.02 | Intravenous Tranexamic Acid Reduces Blood Loss and Transfusion Volume in Scoliosis Surgery for Spinal Muscular Atrophy: Results of a 20-Year Retrospective Analysis. ( Chou, SH; Jong, YJ; Liang, WC; Lin, SY; Lu, CC; Lu, YM; Shih, CL; Tien, YC; Wu, MH, 2021) |
| "Previous studies have demonstrated that the use of tranexamic acid (TXA) reduces blood loss and transfusion requirements in children undergoing scoliosis surgery." | 8.02 | A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. ( Bronson, WE; Halpern, LM; Kogan, CJ, 2021) |
| "The aim of the present study was to investigate whether an innovative way of administering tranexamic acid (TXA), that is, injecting it retrogradely through the drain and clamping it for 1 h, can reduce postoperative bleeding after degenerative lumbar scoliosis surgery." | 7.96 | Topical Injection of Tranexamic Acid via a Drain Plus Drain-Clamping to Reduce Blood Loss in Degenerative Lumbar Scoliosis Surgery. ( Chang, L; Liang, JQ; Liu, HZ; Liu, XY; Rong, TH; Tan, MS; Zhao, H, 2020) |
| "Our objective was to quantify blood loss and transfusion requirements for high-dose and low-dose tranexamic acid (TXA) dosing regimens in pediatric patients undergoing spinal fusion for correction of idiopathic scoliosis." | 7.85 | High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery. ( Frank, SM; Goobie, SM; Johnson, CC; Johnson, DJ; Nami, N; Sponseller, PD; Wetzler, JA, 2017) |
| "Use of large dose tranexamic acid routinely seems to be effective and safe in reducing allogenic blood transfusion and blood loss in adolescent idiopathic scoliosis surgery." | 7.83 | Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Sui, WY; Yang, JL; Ye, F, 2016) |
| "To assess the efficacy and safety of tranexamic acid (TXA) in decreasing operative blood loss and the need for transfusion during posterior spinal fusion for the treatment of idiopathic scoliosis in adolescents." | 7.78 | Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? ( Fukuda, K; Hasegawa, J; Iizuka, S; Kaneko, S; Machida, M; Nagoshi, N; Shioda, M; Takemitsu, M; Yagi, M, 2012) |
| "A retrospective review of consecutive adult patients undergoing scoliosis correction surgery was performed to compare the effects of aprotinin and tranexamic acid in blood conservation and to define a comprehensive blood conservation strategy for such surgery." | 7.78 | Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. ( Ahuja, S; Guha, A; Khurana, A; Pugh, S; Saxena, N, 2012) |
| "We compared intraoperative blood loss and blood replacement during spinal fusion surgery for scoliosis in Duchenne muscular dystrophy (DMD) performed with and without the synthetic antifibrinolytic agent tranexamic acid (TXA)." | 7.74 | Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis. ( Sethna, NF; Shapiro, F; Zurakowski, D, 2007) |
| "Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss." | 6.87 | Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial. ( Brustowicz, RM; Emans, JB; Glotzbecker, MP; Goobie, SM; Hedequist, D; Hresko, MT; Karlin, LI; McCann, ME; Sethna, NF; Zurakowski, D, 2018) |
| "Tranexamic acid (TXA) has been widely used in orthopedic surgery, but its efficacy in adolescent scoliosis (AS) surgery remains unclear in the literature." | 5.41 | Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis. ( Chen, K; Gao, Q; Masood, U; Song, Y; Wang, L; Yang, H; Zeng, Z, 2023) |
| "Tranexamic acid (TXA) is widely used in surgery for adolescent idiopathic scoliosis (AIS) and has been proved to be efficacious in reducing intraoperative blood loss (IBL) and the transfusion rate." | 5.41 | The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial. ( Liu, LM; Song, YM; Wang, L; Wang, LN; Xiu, P; Yang, X; Zhang, Z; Zhou, ZJ, 2021) |
| "The objective of this study is to determine the efficacy of high-dose versus low-dose tranexamic acid (TXA) in adolescent idiopathic scoliosis (AIS) corrective surgery." | 5.41 | Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery. ( Chan, CYW; Chiu, CK; Hasan, MS; Kwan, MK; Ng, CC; Yunus, SN, 2021) |
| "To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TXA alone." | 5.41 | Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial. ( Dong, Y; Li, Q; Liang, J; Shen, J; Tong, B; Zhao, H, 2021) |
| "We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn." | 5.24 | Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery. ( Endo, N; Kohno, T; Ohashi, M; Ohashi, N, 2017) |
| " The primary aim of this study was to determine the efficacy of intraoperative tranexamic acid, epsilon-aminocaproic acid, and placebo at reducing perioperative blood loss and the transfusion rate in patients with adolescent idiopathic scoliosis undergoing posterior spinal arthrodesis." | 5.19 | The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. ( Boenigk, K; Diefenbach, C; Dryer, J; Errico, T; Hoelscher, C; Huncke, T; Lonner, BS; Peters, A; Verma, K, 2014) |
| "This study aimed to evaluate the efficacy and safety of using high-dose intravenous tranexamic acid (TXA) to reduce blood loss in idiopathic scoliosis surgery." | 5.12 | The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis. ( Chen, JC; Lin, L; Na, XQ; Qu, QC; Ruan, TY; Shrestha, IK; Si, YY; Tan, M; Tao, JP, 2021) |
| "Intraoperative administration of tranexamic acid significantly reduces blood loss during spinal surgery in children with scoliosis." | 5.11 | Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. ( Bacsik, J; Brustowicz, RM; Sethna, NF; Shapiro, F; Sullivan, LJ; Zurakowski, D, 2005) |
| "The administration of prophylactic tranexamic acid in patients with scoliosis who are undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements." | 5.09 | A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. ( Barrowman, NJ; Hall, L; Murto, K; Neilipovitz, DT; Splinter, WM, 2001) |
| "To evaluate the efficacy and safety of tranexamic acid (TXA) in patients with adolescent idiopathic scoliosis undergoing corrective surgery." | 5.01 | The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis. ( Cao, K; Lin, N; Lu, H; Wang, B; Zhong, J; Zhou, X, 2019) |
| "The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of tranexamic acid (TXA) versus placebo after a scoliosis surgery." | 4.95 | Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis. ( Xu, BS; Yuan, QM; Zhao, ZH, 2017) |
| "A systematic review of the literature was conducted to identify all randomized controlled trials of aprotinin, tranexamic acid, and aminocaproic acid involving children undergoing cardiac or scoliosis surgery." | 4.85 | The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. ( Bollen, CW; Jansen, NJ; Schouten, AN; Schouten, ES; Turner, NM; van de Pol, AC, 2009) |
| "The administration of tranexamic acid (TXA) has been shown to be beneficial in reducing blood loss during surgery for adolescent idiopathic scoliosis (AIS), but optimal dosing has yet to be defined." | 4.12 | High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis. ( Bacon, A; Javidan, Y; Klineberg, E; Roberto, R; Stondell, C; Tafoya, S; Taylor, SL; Tumber, S, 2022) |
| "The utility of tranexamic acid (TXA) in patients with Marfan syndrome (MFS) is uncertain given associated aberrations within the vasculature and clotting cascade." | 4.12 | Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome. ( Ikwuezunma, IA; Margalit, A; Sponseller, PD, 2022) |
| "Previous studies have demonstrated that the use of tranexamic acid (TXA) reduces blood loss and transfusion requirements in children undergoing scoliosis surgery." | 4.02 | A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. ( Bronson, WE; Halpern, LM; Kogan, CJ, 2021) |
| "Intravenous tranexamic acid (TXA) has been administered to reduce intraoperative blood loss in scoliosis surgery." | 4.02 | Intravenous Tranexamic Acid Reduces Blood Loss and Transfusion Volume in Scoliosis Surgery for Spinal Muscular Atrophy: Results of a 20-Year Retrospective Analysis. ( Chou, SH; Jong, YJ; Liang, WC; Lin, SY; Lu, CC; Lu, YM; Shih, CL; Tien, YC; Wu, MH, 2021) |
| "The application of a protocol for blood and fluid management, based on goal-directed fluid therapy, cell salvage and tranexamic acid, was associated with less crystalloid fluid administration, less perioperative RBC transfusions and significantly better diuresis than patients in the no-protocol group in scoliosis surgery." | 3.96 | Blood and fluid management during scoliosis surgery: a single-center retrospective analysis. ( Chatzopoulos, S; Gkiouliava, A; Koraki, E; Sifaki, F; Stachtari, C; Stamatopoulou, M; Stergiouda, Z; Trikoupi, A, 2020) |
| "The aim of the present study was to investigate whether an innovative way of administering tranexamic acid (TXA), that is, injecting it retrogradely through the drain and clamping it for 1 h, can reduce postoperative bleeding after degenerative lumbar scoliosis surgery." | 3.96 | Topical Injection of Tranexamic Acid via a Drain Plus Drain-Clamping to Reduce Blood Loss in Degenerative Lumbar Scoliosis Surgery. ( Chang, L; Liang, JQ; Liu, HZ; Liu, XY; Rong, TH; Tan, MS; Zhao, H, 2020) |
| "Antifibrinolytics such as tranexamic acid reduce operative blood loss and blood product transfusion requirements in patients undergoing surgical correction of scoliosis." | 3.88 | Effect of Tranexamic Acid on Blood Loss, D-Dimer, and Fibrinogen Kinetics in Adult Spinal Deformity Surgery. ( Edwards, A; Herodes, M; Leveque, JA; Pong, RP; Sethi, RK; Wright, AK; Yanamadala, V, 2018) |
| "Our objective was to quantify blood loss and transfusion requirements for high-dose and low-dose tranexamic acid (TXA) dosing regimens in pediatric patients undergoing spinal fusion for correction of idiopathic scoliosis." | 3.85 | High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery. ( Frank, SM; Goobie, SM; Johnson, CC; Johnson, DJ; Nami, N; Sponseller, PD; Wetzler, JA, 2017) |
| "Use of large dose tranexamic acid routinely seems to be effective and safe in reducing allogenic blood transfusion and blood loss in adolescent idiopathic scoliosis surgery." | 3.83 | Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Sui, WY; Yang, JL; Ye, F, 2016) |
| "The aim of this study was to compare transfusion requirements in patients before and after the introduction of tranexamic acid as standard in patients undergoing spinal surgery for idiopathic scoliosis in a national orthopaedic hospital." | 3.81 | Eliminating the use of allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Berney, MJ; Connolly, P; Dawson, PH; Lui, DF; Phillips, M, 2015) |
| "A retrospective review of consecutive adult patients undergoing scoliosis correction surgery was performed to compare the effects of aprotinin and tranexamic acid in blood conservation and to define a comprehensive blood conservation strategy for such surgery." | 3.78 | Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. ( Ahuja, S; Guha, A; Khurana, A; Pugh, S; Saxena, N, 2012) |
| "To assess the efficacy and safety of tranexamic acid (TXA) in decreasing operative blood loss and the need for transfusion during posterior spinal fusion for the treatment of idiopathic scoliosis in adolescents." | 3.78 | Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? ( Fukuda, K; Hasegawa, J; Iizuka, S; Kaneko, S; Machida, M; Nagoshi, N; Shioda, M; Takemitsu, M; Yagi, M, 2012) |
| "We compared intraoperative blood loss and blood replacement during spinal fusion surgery for scoliosis in Duchenne muscular dystrophy (DMD) performed with and without the synthetic antifibrinolytic agent tranexamic acid (TXA)." | 3.74 | Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis. ( Sethna, NF; Shapiro, F; Zurakowski, D, 2007) |
| "The use of rFIX, rFVIIa, erythropoetin, iron, and tranexamic acid before, during and after scoliosis surgery may be a viable and safe option for hemophilia patients with inhibitors, who refuse blood products." | 3.74 | [A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery]. ( Ansermino, M; Chau, A; Purdy, R; Tredwell, S; Wu, J, 2008) |
| "Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss." | 2.87 | Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial. ( Brustowicz, RM; Emans, JB; Glotzbecker, MP; Goobie, SM; Hedequist, D; Hresko, MT; Karlin, LI; McCann, ME; Sethna, NF; Zurakowski, D, 2018) |
| "Tranexamic acid (TXA) is an effective and commonly used hemostatic agent for perioperative blood loss in various surgical specialties." | 2.72 | Advances in surgical hemostasis: a comprehensive review and meta-analysis on topical tranexamic acid in spinal deformity surgery. ( Barra, ME; Fatima, N; Hadzipasic, M; Massaad, E; Roberts, RJ; Shankar, GM; Shin, JH, 2021) |
| "The incidence of seizure, stoke, PE, or DVT in the control group was 0." | 1.72 | Evaluation of the safety of tranexamic acid use in pediatric patients undergoing spinal fusion surgery: a retrospective comparative cohort study. ( Chang, PS; Chatterjee, A; Geiselmann, MT; Ivasyk, I; Jordan, C; Kamel, H; Khormaee, S, 2022) |
| "Spinal surgery for scoliosis has been performed in selected patients with single ventricle physiology at a single institution without mortality for 25 years." | 1.62 | Surgical Correction of Scoliosis in Children with Severe Congenital Heart Disease and Palliated Single Ventricle Physiology. ( Cohen, LL; Emans, JB; Hedequist, DJ; Marshall, AC; Przybylski, R, 2021) |
| "Tranexamic acid (TXA) was found to be more effective at reducing total blood loss compared with epsilon-aminocaproic acid (AM) than placebo." | 1.48 | Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice? ( Asghar, J; Lonner, BS; Newton, PO; Ren, Y; Samdani, AF; Shah, SA, 2018) |
| "Average preoperative major deformity (kyphosis or scoliosis) was 97° ± 31°." | 1.38 | Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. ( Bastrom, TP; Emans, JB; Lenke, LG; Newton, PO; Shah, SA; Shufflebarger, HL; Sponseller, PD; Sucato, DJ, 2012) |
| "Blood conservation; the area of greatest clinical variability was seen in dosing regimes for Tranexamic acid." | 1.37 | Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice. ( Bird, S; McGill, N, 2011) |
| "IV tranexamic acid was also administered to reduce intraoperative blood loss." | 1.35 | Routine preoperative coagulation screening detects a rare bleeding disorder. ( Anne, KK; Durga, P; Jonnavithula, N; Pochiraju, R; Ramachandran, G, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (16.67) | 29.6817 |
| 2010's | 21 (43.75) | 24.3611 |
| 2020's | 19 (39.58) | 2.80 |
| Authors | Studies |
|---|---|
| Ikwuezunma, IA | 1 |
| Margalit, A | 1 |
| Sponseller, PD | 4 |
| Chou, SH | 1 |
| Lin, SY | 1 |
| Wu, MH | 1 |
| Tien, YC | 1 |
| Jong, YJ | 1 |
| Liang, WC | 1 |
| Lu, YM | 1 |
| Shih, CL | 1 |
| Lu, CC | 1 |
| Ahlers, CG | 1 |
| Lan, M | 1 |
| Schoenecker, JG | 1 |
| Borst, AJ | 1 |
| Eaker, L | 1 |
| Selverian, SR | 1 |
| Hodo, LN | 1 |
| Gal, J | 1 |
| Gangadharan, S | 1 |
| Meyers, J | 1 |
| Dolgopolov, S | 1 |
| Lonner, B | 1 |
| Ivasyk, I | 1 |
| Chatterjee, A | 1 |
| Jordan, C | 1 |
| Geiselmann, MT | 1 |
| Chang, PS | 1 |
| Kamel, H | 1 |
| Khormaee, S | 1 |
| Chen, K | 1 |
| Wang, L | 2 |
| Gao, Q | 1 |
| Masood, U | 1 |
| Zeng, Z | 1 |
| Yang, H | 1 |
| Song, Y | 1 |
| Lonner, BS | 3 |
| Ren, Y | 1 |
| Asghar, J | 1 |
| Shah, SA | 3 |
| Samdani, AF | 1 |
| Newton, PO | 3 |
| Bosch, P | 1 |
| Kenkre, TS | 1 |
| Soliman, D | 1 |
| Londino, JA | 1 |
| Novak, NE | 1 |
| Liang, JQ | 1 |
| Rong, TH | 1 |
| Liu, HZ | 1 |
| Tan, MS | 1 |
| Zhao, H | 2 |
| Liu, XY | 1 |
| Chang, L | 1 |
| Fatima, N | 1 |
| Barra, ME | 1 |
| Roberts, RJ | 1 |
| Massaad, E | 1 |
| Hadzipasic, M | 1 |
| Shankar, GM | 1 |
| Shin, JH | 1 |
| Koraki, E | 1 |
| Stachtari, C | 1 |
| Stergiouda, Z | 1 |
| Stamatopoulou, M | 1 |
| Gkiouliava, A | 1 |
| Sifaki, F | 1 |
| Chatzopoulos, S | 1 |
| Trikoupi, A | 1 |
| Yang, L | 1 |
| Jia, X | 1 |
| Yang, J | 1 |
| Kang, J | 1 |
| Zhang, Z | 1 |
| Wang, LN | 1 |
| Yang, X | 1 |
| Liu, LM | 1 |
| Xiu, P | 1 |
| Zhou, ZJ | 1 |
| Song, YM | 1 |
| Cohen, LL | 1 |
| Przybylski, R | 1 |
| Marshall, AC | 1 |
| Emans, JB | 3 |
| Hedequist, DJ | 1 |
| Shrestha, IK | 1 |
| Ruan, TY | 1 |
| Lin, L | 1 |
| Tan, M | 1 |
| Na, XQ | 1 |
| Qu, QC | 1 |
| Chen, JC | 1 |
| Si, YY | 1 |
| Tao, JP | 1 |
| Halpern, LM | 1 |
| Bronson, WE | 1 |
| Kogan, CJ | 1 |
| George, S | 1 |
| Ramchandran, S | 1 |
| Mihas, A | 1 |
| George, K | 1 |
| Mansour, A | 1 |
| Errico, T | 2 |
| Hasan, MS | 1 |
| Yunus, SN | 1 |
| Ng, CC | 1 |
| Chan, CYW | 1 |
| Chiu, CK | 1 |
| Kwan, MK | 1 |
| Tumber, S | 1 |
| Bacon, A | 1 |
| Stondell, C | 1 |
| Tafoya, S | 1 |
| Taylor, SL | 1 |
| Javidan, Y | 1 |
| Klineberg, E | 1 |
| Roberto, R | 1 |
| Dong, Y | 1 |
| Liang, J | 1 |
| Tong, B | 1 |
| Shen, J | 1 |
| Li, Q | 1 |
| Yuan, L | 1 |
| Jiang, Y | 1 |
| Liu, Y | 1 |
| Zeng, Y | 1 |
| Chen, Z | 1 |
| Li, W | 1 |
| Johnson, DJ | 1 |
| Johnson, CC | 1 |
| Goobie, SM | 2 |
| Nami, N | 1 |
| Wetzler, JA | 1 |
| Frank, SM | 1 |
| Zhou, K | 1 |
| Shakya, H | 1 |
| Luo, Z | 1 |
| Zhou, Z | 1 |
| Pei, F | 1 |
| Clark, N | 1 |
| Morris, S | 1 |
| Sargant, N | 1 |
| Pong, RP | 1 |
| Leveque, JA | 1 |
| Edwards, A | 1 |
| Yanamadala, V | 1 |
| Wright, AK | 1 |
| Herodes, M | 1 |
| Sethi, RK | 1 |
| Zurakowski, D | 3 |
| Glotzbecker, MP | 1 |
| McCann, ME | 1 |
| Hedequist, D | 1 |
| Brustowicz, RM | 2 |
| Sethna, NF | 3 |
| Karlin, LI | 1 |
| Hresko, MT | 1 |
| Buell, TJ | 1 |
| Taylor, DG | 1 |
| Chen, CJ | 1 |
| Dunn, LK | 1 |
| Mullin, JP | 1 |
| Mazur, MD | 1 |
| Yen, CP | 1 |
| Shaffrey, ME | 1 |
| Shaffrey, CI | 1 |
| Smith, JS | 1 |
| Naik, BI | 1 |
| Zhong, J | 1 |
| Cao, K | 1 |
| Wang, B | 1 |
| Zhou, X | 1 |
| Lin, N | 1 |
| Lu, H | 1 |
| Verma, K | 2 |
| Diefenbach, C | 1 |
| Hoelscher, C | 1 |
| Peters, A | 1 |
| Dryer, J | 1 |
| Huncke, T | 1 |
| Boenigk, K | 1 |
| Berney, MJ | 1 |
| Dawson, PH | 1 |
| Phillips, M | 1 |
| Lui, DF | 1 |
| Connolly, P | 1 |
| Sui, WY | 1 |
| Ye, F | 1 |
| Yang, JL | 1 |
| Yuan, QM | 1 |
| Zhao, ZH | 1 |
| Xu, BS | 1 |
| Ohashi, N | 1 |
| Ohashi, M | 1 |
| Endo, N | 1 |
| Kohno, T | 1 |
| Jonnavithula, N | 1 |
| Durga, P | 1 |
| Pochiraju, R | 1 |
| Anne, KK | 1 |
| Ramachandran, G | 1 |
| Schouten, ES | 1 |
| van de Pol, AC | 1 |
| Schouten, AN | 1 |
| Turner, NM | 1 |
| Jansen, NJ | 1 |
| Bollen, CW | 1 |
| Errico, TJ | 1 |
| Vaz, KM | 1 |
| Bird, S | 1 |
| McGill, N | 1 |
| Xu, C | 1 |
| Wu, A | 1 |
| Yue, Y | 1 |
| Dhawale, AA | 1 |
| Bastrom, T | 1 |
| Neiss, G | 1 |
| Yorgova, P | 1 |
| Yaszay, B | 1 |
| Abel, MF | 1 |
| Shufflebarger, H | 1 |
| Gabos, PG | 1 |
| Dabney, KW | 1 |
| Miller, F | 1 |
| Khurana, A | 1 |
| Guha, A | 1 |
| Saxena, N | 1 |
| Pugh, S | 1 |
| Ahuja, S | 1 |
| Yagi, M | 1 |
| Hasegawa, J | 1 |
| Nagoshi, N | 1 |
| Iizuka, S | 1 |
| Kaneko, S | 1 |
| Fukuda, K | 1 |
| Takemitsu, M | 1 |
| Shioda, M | 1 |
| Machida, M | 1 |
| Bastrom, TP | 1 |
| Shufflebarger, HL | 1 |
| Sucato, DJ | 1 |
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| Neilipovitz, DT | 2 |
| Bacsik, J | 1 |
| Sullivan, LJ | 1 |
| Shapiro, F | 2 |
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| Ansermino, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Blood and Fluid Management During Scoliosis Surgery: A Single Center Retrospective Analysis[NCT03814239] | 35 participants (Actual) | Observational | 2011-10-30 | Completed | |||
| The Effectiveness Of Intravenous Tranexamic Acid (TXA) on Reducing Perioperative Blood Loss For Patients Undergoing Periacetabular Osteotomy (PAO): A Randomized Double Blind Placebo Controlled Trial[NCT03823417] | Phase 4 | 0 participants (Actual) | Interventional | 2019-07-31 | Withdrawn (stopped due to Investigators decided not to begin the study.) | ||
| Does Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Reduce Blood Loss and Transfusion Requirements? A Double-blinded Randomized Controlled Trial[NCT05024253] | Phase 3 | 48 participants (Anticipated) | Interventional | 2021-08-02 | Recruiting | ||
| Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238] | Phase 2 | 130 participants (Anticipated) | Interventional | 2023-04-12 | Recruiting | ||
| A Prospective, Randomized, Double-blinded Single-site Control Study Comparing Blood Loss Prevention of Tranexamic Acid (TXA) to Epsilon Aminocaproic Acid (EACA) for Corrective Spinal Surgery[NCT00958581] | Phase 4 | 177 participants (Actual) | Interventional | 2008-12-31 | Completed | ||
| Low Versus High Dose Tranexamic Acid in Adult Spinal Deformity Surgery: A Randomized, Blinded, Controlled Trial[NCT02053363] | Phase 2/Phase 3 | 64 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| Tranexamic Acid for the Reduction of Allogeneic Blood Exposure in Infants and Children Having Craniofacial Surgery[NCT00722436] | Phase 4 | 20 participants (Actual) | Interventional | 2008-07-31 | Terminated (stopped due to Study dose changed based on recent publications) | ||
| The Efficacy of Intravenous Tranexamic Acid in Decreasing Blood Loss in Pediatric Idiopathic Scoliosis Surgery?[NCT01813058] | Phase 1/Phase 2 | 120 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00958581)
Timeframe: 1 Week
| Intervention | ml (Mean) |
|---|---|
| Epsilon Aminocaproic Acid | 1775 |
| Normal Saline | 2116 |
| Tranexamic Acid | 1531 |
"To compare the estimated blood loss in patients undergoing complex, reconstructive, spinal fusion surgeries receiving one of two dosing protocols for the anti-fibrinolytic, TXA.~Estimated blood loss was calculated by suction canister volume minus intraoperative irrigation fluid plus blood content in sponges as estimated by weight for all cases." (NCT02053363)
Timeframe: This outcome is measured during surgery, from exposure to wound closure, approximately 8 hours.
| Intervention | mL (Mean) |
|---|---|
| High Dose/Study Group | 2046 |
| Standard of Care/Control | 1596 |
To compare the rates of intraoperative complications and 90 day complications observed in the two groups. (NCT02053363)
Timeframe: Perioperative complications were defined as complications occurring within 90 days of surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| High Dose/Study Group | 2 |
| Standard of Care/Control | 3 |
To compare the mean volume (mL) of packed red blood cell (PRBC) transfusions given to the two groups. Volumes of RBC vary from bag to bag and real volumes will be recorded as provided by the blood bank. (NCT02053363)
Timeframe: Participants will be followed for the duration of their hospital stay measured from day of surgery to day of discharge from the hospital, approximately 7 days.
| Intervention | mL (Mean) |
|---|---|
| High Dose/Study Group | 1259 |
| Standard of Care/Control | 935 |
(NCT00722436)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Tranexamic Acid | 2 |
| Placebo | 0 |
This is the blood administered during surgery. The blood comes form the blood bank. It is not cell salvage blood. The volume was normalized by weight. (NCT00722436)
Timeframe: intraoperative and postoperative (24 hr)
| Intervention | ml/kg (Mean) |
|---|---|
| Tranexamic Acid | 16.1 |
| Placebo | 17.1 |
(NCT00722436)
Timeframe: (baseline, after osteotomies, and immediately after procedure)
| Intervention | seconds (Mean) | |||||
|---|---|---|---|---|---|---|
| PT -baseline | PT-after osteotomies | PT-immediately after surgery | PTT -baseline | PTT-after osteotomies | PTT-immediately after surgery | |
| Placebo | 13.8 | 16.1 | 17 | 32.9 | 34.6 | 34.8 |
| Tranexamic Acid | 15.1 | 18.5 | 17.7 | 34.6 | 37.2 | 33.3 |
(NCT00722436)
Timeframe: baseline, after osteotomies, immediately after surgery
| Intervention | 10^9 platelets/L (Mean) | ||
|---|---|---|---|
| platelets-baseline | platelets-after osteotomies | platelets-immediately after surgery | |
| Placebo | 364 | 300 | 231 |
| Tranexamic Acid | 301 | 253 | 223 |
Perioperative blood loss (during operation and for entire hospital admission) (NCT01813058)
Timeframe: perioperarively - during entire hospital admission
| Intervention | mL (Mean) |
|---|---|
| Placebo | 1031 |
| Tranexamic Acid | 836 |
8 reviews available for tranexamic acid and Scoliosis
| Article | Year |
|---|---|
Blood Loss and Transfusion in a Pediatric Scoliosis Surgery Cohort in the Antifibrinolytic Era.
Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Humans; Retrosp | 2022 |
Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis.
Topics: Adolescent; Blood Loss, Surgical; Exsanguination; Humans; Orthopedic Procedures; Scoliosis; Tranexam | 2023 |
Advances in surgical hemostasis: a comprehensive review and meta-analysis on topical tranexamic acid in spinal deformity surgery.
Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostatic Techniques; Human | 2021 |
The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis.
Topics: Adolescent; Blood Loss, Surgical; Female; Humans; Infusions, Intravenous; Intraoperative Complicatio | 2021 |
The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Scoliosis; Spinal F | 2019 |
Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Postoperative Hemorrhage; Scolio | 2017 |
The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis.
Topics: Aminocaproates; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Child; Hemostatics; Humans; Plac | 2009 |
Tranexamic acid for major spinal surgery.
Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Humans; Scolios | 2004 |
12 trials available for tranexamic acid and Scoliosis
| Article | Year |
|---|---|
Tranexamic acid reduces blood cost in long-segment spinal fusion surgery: A randomized controlled study protocol.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female; Human | 2020 |
The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial.
Topics: Administration, Intravenous; Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Post | 2021 |
Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery.
Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Humans; Prospective Studies | 2021 |
Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial.
Topics: Administration, Intravenous; Administration, Topical; Adolescent; Antifibrinolytic Agents; Blood Los | 2021 |
Cost-Benefit Analysis of Using A Single Dose of Tranexamic Acid in Degenerative Lumbar Scoliosis Patients Undergoing Long-Segment Spinal Fusion Surgery: A Retrospective Study.
Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Decision-Making; Combined Modality The | 2021 |
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F | 2018 |
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F | 2018 |
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F | 2018 |
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F | 2018 |
The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial.
Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Dou | 2014 |
Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery.
Topics: Adolescent; Animals; Blood Loss, Surgical; Female; Humans; Male; Nociception; Pain; Rats; Scoliosis; | 2017 |
A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, | 2010 |
Which is more effective in adolescent idiopathic scoliosis surgery: batroxobin, tranexamic acid or a combination?
Topics: Adolescent; Antifibrinolytic Agents; Batroxobin; Blood Loss, Surgical; Blood Transfusion; Drainage; | 2012 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C | 2005 |
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio | 2001 |
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio | 2001 |
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio | 2001 |
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio | 2001 |
28 other studies available for tranexamic acid and Scoliosis
| Article | Year |
|---|---|
Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Marfan Syndrome; Scoliosis; Tranexamic Acid | 2022 |
Intravenous Tranexamic Acid Reduces Blood Loss and Transfusion Volume in Scoliosis Surgery for Spinal Muscular Atrophy: Results of a 20-Year Retrospective Analysis.
Topics: Antifibrinolytic Agents; Blood Transfusion; Humans; Muscular Atrophy, Spinal; Retrospective Studies; | 2021 |
Post-operative tranexamic acid decreases chest tube drainage following vertebral body tethering surgery for scoliosis correction.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Chest Tubes; Drainage; Humans; Scoliosis; | 2022 |
Evaluation of the safety of tranexamic acid use in pediatric patients undergoing spinal fusion surgery: a retrospective comparative cohort study.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Cohort Studies; Humans; Pulmonary | 2022 |
Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice?
Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Cohort Studies; | 2018 |
Comparison of the Coagulation Profile of Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion With and Without Tranexamic Acid.
Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio | 2019 |
Topical Injection of Tranexamic Acid via a Drain Plus Drain-Clamping to Reduce Blood Loss in Degenerative Lumbar Scoliosis Surgery.
Topics: Aged; Antifibrinolytic Agents; Decompression, Surgical; Drainage; Female; Humans; Injections, Intra- | 2020 |
Blood and fluid management during scoliosis surgery: a single-center retrospective analysis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Transfusion, Autologous; Clinical Protocols; Crystalloid | 2020 |
Surgical Correction of Scoliosis in Children with Severe Congenital Heart Disease and Palliated Single Ventricle Physiology.
Topics: Adolescent; Adult; Child; Cohort Studies; Female; Heart Defects, Congenital; Heart Ventricles; Human | 2021 |
A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Humans; Kyphosi | 2021 |
Topical tranexemic acid reduces intra-operative blood loss and transfusion requirements in spinal deformity correction in patients with adolescent idiopathic scoliosis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Scolio | 2021 |
High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Retrospective | 2022 |
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R | 2017 |
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R | 2017 |
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R | 2017 |
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R | 2017 |
Letter to the Editor concerning ''Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis.'' by Yuan, QM. et al. (Eur Spine J; 2017. doi:10.1007/s00586-016-4899-0).
Topics: Hemorrhage; Humans; Scoliosis; Tranexamic Acid | 2018 |
Comment on Chiem J, Ivanova I, Jimenez N. Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
Topics: Adolescent; Anaphylaxis; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Scoliosis; Spinal Fu | 2018 |
Effect of Tranexamic Acid on Blood Loss, D-Dimer, and Fibrinogen Kinetics in Adult Spinal Deformity Surgery.
Topics: Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Female; Fibrin Fibrinoge | 2018 |
Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Co | 2019 |
Eliminating the use of allogeneic blood products in adolescent idiopathic scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; H | 2015 |
Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Male; | 2016 |
Routine preoperative coagulation screening detects a rare bleeding disorder.
Topics: Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Child; Factor X Deficien | 2009 |
Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice.
Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia; Anticoagulants; Antifibrinolytic Ag | 2011 |
Are antifibrinolytics helpful in decreasing blood loss and transfusions during spinal fusion surgery in children with cerebral palsy scoliosis?
Topics: Adolescent; Aminocaproic Acid; Analysis of Variance; Antifibrinolytic Agents; Blood Loss, Surgical; | 2012 |
Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery.
Topics: Adolescent; Adult; Aged; Aprotinin; Blood Loss, Surgical; Female; Hemostasis, Surgical; Hemostatics; | 2012 |
Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis?
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Female; Humans; | 2012 |
Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures.
Topics: Adolescent; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfus | 2012 |
Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Child; E | 2007 |
[A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery].
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Dietary Supplements; Epoetin Alfa; Erythr | 2008 |
Re: Shapiro F, Zurakowski D, Sethna NF. Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusion for Duchenne muscular dystrophy scoliosis. Spine 2007;32:2278-83.
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Child; E | 2008 |