Page last updated: 2024-11-05

tranexamic acid and Sarcoma

tranexamic acid has been researched along with Sarcoma in 6 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid (TXA) is poorly studied in patients with bone and musculoskeletal sarcoma due to perceived increased risk of venous thromboembolism (VTE)."8.31Intravenous tranexamic acid decreases intraoperative transfusion requirements and does not increase incidence of symptomatic venous thromboembolic events in musculoskeletal sarcoma surgery. ( Andrews, NA; Crowley, B; Hess, MC; Howie, C; McGwin, G; Siegel, H; Singh, NP, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce blood loss following surgery."5.91Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection. ( Foster, D; Garner, H; Goulding, K; Houdek, M; Sebro, R; Spaulding, AC; Stanborough, R; Wilke, B, 2023)
"The aim of the present study was to assess the incidence of and risk factors for thromboembolic events-including assessment of the intraoperative use of tranexamic acid and postoperative use of chemical thromboprophylaxis-in patients undergoing operative treatment of primary bone or soft-tissue sarcoma or oligometastatic bone disease."5.69Incidence of and Risk Factors for Thromboembolism After Endoprosthetic Reconstruction in Musculoskeletal Oncology Patients. ( Forsberg, JA; Levin, AS; LiBrizzi, CL; Morris, CD; Sabharwal, S, 2023)
"Tranexamic acid (TXA) is poorly studied in patients with bone and musculoskeletal sarcoma due to perceived increased risk of venous thromboembolism (VTE)."4.31Intravenous tranexamic acid decreases intraoperative transfusion requirements and does not increase incidence of symptomatic venous thromboembolic events in musculoskeletal sarcoma surgery. ( Andrews, NA; Crowley, B; Hess, MC; Howie, C; McGwin, G; Siegel, H; Singh, NP, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce blood loss following surgery."1.91Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection. ( Foster, D; Garner, H; Goulding, K; Houdek, M; Sebro, R; Spaulding, AC; Stanborough, R; Wilke, B, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic agent used to reduce blood loss in orthopaedic procedures."1.56Tranexamic Acid in Patients With Cancer Undergoing Endoprosthetic Reconstruction: A Retrospective Review. ( Haase, DR; Rosenthal, HG; Sweeney, KR; Templeton, KJ, 2020)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's5 (83.33)2.80

Authors

AuthorsStudies
Foster, D1
Sebro, R1
Garner, H1
Stanborough, R1
Spaulding, AC1
Goulding, K1
Houdek, M1
Wilke, B1
Sabharwal, S1
LiBrizzi, CL1
Forsberg, JA1
Morris, CD1
Levin, AS1
Hess, MC1
Andrews, NA1
Crowley, B1
Singh, NP1
Howie, C1
McGwin, G1
Siegel, H1
Haase, DR1
Templeton, KJ1
Rosenthal, HG1
Sweeney, KR1
Langhorn, R1
Poulsen, MK1
Heidemann, PL1
Bochsen, L1
Ritz, C1
Kristensen, AT1
Nielsen, LN1
Sajdak, S1
Moszynski, R1
Opala, T1

Trials

1 trial available for tranexamic acid and Sarcoma

ArticleYear
Incidence of and Risk Factors for Thromboembolism After Endoprosthetic Reconstruction in Musculoskeletal Oncology Patients.
    The Journal of bone and joint surgery. American volume, 2023, 07-19, Volume: 105, Issue:Suppl 1

    Topics: Adult; Aged; Anticoagulants; Bone Diseases; Child; Humans; Incidence; Middle Aged; Prospective Studi

2023

Other Studies

5 other studies available for tranexamic acid and Sarcoma

ArticleYear
Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection.
    Journal of surgical oncology, 2023, Volume: 128, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Complications; Pulmonary Emboli

2023
Intravenous tranexamic acid decreases intraoperative transfusion requirements and does not increase incidence of symptomatic venous thromboembolic events in musculoskeletal sarcoma surgery.
    Surgical oncology, 2023, Volume: 50

    Topics: Adult; Humans; Incidence; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms; Tranexamic Acid; Ve

2023
Tranexamic Acid in Patients With Cancer Undergoing Endoprosthetic Reconstruction: A Retrospective Review.
    The Journal of the American Academy of Orthopaedic Surgeons, 2020, Mar-15, Volume: 28, Issue:6

    Topics: Antifibrinolytic Agents; Bone Neoplasms; Femur; Humans; Plastic Surgery Procedures; Postoperative He

2020
Diagnosis of primary hyperfibrinolysis and in vitro investigation of the inhibitory effects of tranexamic acid in a group of dogs with sarcomas - A pilot study.
    Research in veterinary science, 2021, Volume: 136

    Topics: Animals; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Tests; Case-Control

2021
Bleeding from endometrial and vaginal malignant tumors treated with activated recombinant factor VII.
    European journal of gynaecological oncology, 2002, Volume: 23, Issue:4

    Topics: Adenocarcinoma; Administration, Intravaginal; Adult; Aged; Endometrial Neoplasms; Ethamsylate; Facto

2002