tranexamic acid has been researched along with Renal Insufficiency, Chronic in 3 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The PBM protocol consisted of epoetin (EPO) alfa therapy prescribed by the surgeon, routine administration of tranexamic acid (TXA), an avascular approach to the hip and postoperative prophylaxis of thromboembolism." | 4.02 | Application of an adjusted patient blood management protocol in patients undergoing elective total hip arthroplasty: towards a zero-percent transfusion rate in renal patients-results from an observational cohort study. ( Fennema, P; Hourlier, H, 2021) |
| "Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize bleeding in cardiac surgery." | 1.48 | Tranexamic Acid Dosing for Cardiac Surgical Patients With Chronic Renal Dysfunction: A New Dosing Regimen. ( Beattie, WS; Bojko, B; Jerath, A; Looby, N; Pang, KS; Pawliszyn, J; Reyes-Garces, N; Vasiljevic, T; Wąsowicz, M; Wijeysundera, D; Yang, QJ; Yau, TM, 2018) |
| "She had no further episodes of convulsion till dis-charge and during the two months of follow-up." | 1.40 | Tranexamic acid overdosage-induced generalized seizure in renal failure. ( Agarwal, SK; Bhat, A; Bhowmik, DM; Dogra, M; Vibha, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hourlier, H | 1 |
| Fennema, P | 1 |
| Jerath, A | 1 |
| Yang, QJ | 1 |
| Pang, KS | 1 |
| Looby, N | 1 |
| Reyes-Garces, N | 1 |
| Vasiljevic, T | 1 |
| Bojko, B | 1 |
| Pawliszyn, J | 1 |
| Wijeysundera, D | 1 |
| Beattie, WS | 1 |
| Yau, TM | 1 |
| Wąsowicz, M | 1 |
| Bhat, A | 1 |
| Bhowmik, DM | 1 |
| Vibha, D | 1 |
| Dogra, M | 1 |
| Agarwal, SK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics of Tranexamic Acid in Patients With Varying Renal Function Undergoing Cardiac Surgery With the Use of Cardiopulmonary Bypass[NCT01609686] | 49 participants (Actual) | Observational | 2012-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for tranexamic acid and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Application of an adjusted patient blood management protocol in patients undergoing elective total hip arthroplasty: towards a zero-percent transfusion rate in renal patients-results from an observational cohort study.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic | 2021 |
Tranexamic Acid Dosing for Cardiac Surgical Patients With Chronic Renal Dysfunction: A New Dosing Regimen.
Topics: Aged; Antifibrinolytic Agents; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Drug Administrat | 2018 |
Tranexamic acid overdosage-induced generalized seizure in renal failure.
Topics: Anticonvulsants; Antifibrinolytic Agents; Drug Overdose; Female; Humans; Kidney; Menorrhagia; Middle | 2014 |