Page last updated: 2024-11-05

tranexamic acid and Pain, Postoperative

tranexamic acid has been researched along with Pain, Postoperative in 42 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation."9.41Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021)
"To systematically review the literature to compare the efficacy and safety of tranexamic acid (TXA) as a means to minimize hemarthrosis-related complications after arthroscopic procedures of the knee, hip, and shoulder."9.12Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies. ( Belk, JW; Dragoo, JL; Houck, DA; McCarty, EC; Savoie, FH; Thon, SG, 2021)
"The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation."5.41Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021)
"The aim of this study was to evaluate the effects of a high initial-dose (60 mg/kg) intravenous tranexamic acid (IV-TXA) on fibrinolysis and inflammation after total knee arthroplasty (TKA)."5.34The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial. ( Huang, Q; Huang, W; Lei, YT; Pei, FX; Xie, JW, 2020)
"To systematically review the literature to compare the efficacy and safety of tranexamic acid (TXA) as a means to minimize hemarthrosis-related complications after arthroscopic procedures of the knee, hip, and shoulder."5.12Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies. ( Belk, JW; Dragoo, JL; Houck, DA; McCarty, EC; Savoie, FH; Thon, SG, 2021)
"Tranexamic acid (TXA) has been widely used in orthopedic surgery with the aim of reducing intraoperative and postoperative bleeding, as well as bleeding-related complications."3.30Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients. ( Bildik, C; Pehlivanoglu, T, 2023)
"Tranexamic acid (TXA) has been shown to be effective in reducing blood loss for patients undergoing THA, but few studies focus on its alleviation of postoperative local pain symptoms."3.30Topical use of tranexamic acid can reduce opioid consumption compared with intravenous use for patients undergoing primary total hip arthroplasty: a prospective randomized controlled trial. ( Jiang, Z; Shen, L; Wang, Q; Xu, W, 2023)
"Secondary outcome criteria were postoperative pain, intraarticular effusion (measured by ultrasound), range of motion (ROM) at discharge, peri- and postoperative complications and the KOOS PS (pre- and postoperatively at 1 year follow up)."3.11Use of tranexamic acid in medial open wedge high tibial osteotomy. ( Bentzin, M; Bierke, S; Häner, M; Park, HU; Petersen, W, 2022)
"TXA did not improve postoperative pain scores after RCR, however, patients who received the intervention demonstrated greater range of motion at 6 months with lower rates of secondary adhesive capsulitis."3.11The effect of single-dose, preoperative intravenous tranexamic acid on early postoperative pain scores after rotator cuff repair: a double-blind, randomized controlled trial. ( Bedaiwy, N; Cass, B; Mackenzie, SP; Mattern, O; Patel, SS; Piggott, RP; Smith, M; Spasojevic, M; Young, A, 2022)
"Tranexamic acid (TXA) has been used surgically to decrease blood loss."3.11The effect of tranexamic acid for visualization on pump pressure and visualization during arthroscopic rotator cuff repair: an anonymized, randomized controlled trial. ( Abboud, JA; Churchill, R; Kirsch, JM; Lazarus, MD; Namdari, S; Nicholson, TA, 2022)
"However, there was significantly lower postoperative blood loss with TXA (29."2.94Tranexamic acid for the Latarjet procedure: a randomized controlled trial. ( Hurley, ET; Lim Fat, D; Mullett, H; Pauzenberger, L, 2020)
"Tranexamic acid (TXA) reduces surgical blood loss and alleviates inflammatory response in total hip arthroplasty."2.90Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial. ( He, C; Li, Q; Luo, ZY; Pei, FX; Wang, D; Yang, Y; Zeng, WN; Zhou, ZK, 2019)
"The optimal dosage and timing of tranexamic acid (TXA) in total knee arthroplasty (TKA) are undetermined."2.82Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial. ( Ma, J; Pei, F; Xie, J; Yao, H; Yue, C, 2016)
"placebo on development of alveolitis sicca dolorosa (ASD) had as preoperative registration requirements age, sex, use of oral contraceptives, menstrual cycle, smoking, and degree of impaction at time of operation."2.65Tranexamic acid in alveolar sockets in the prevention of alveolitis sicca dolorosa. ( Gersel-Pedersen, N, 1979)
"However, hemarthrosis is the most common complication in arthroscopic surgery, which has potential adverse effects on postoperative rehabilitation."1.91Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study. ( Chen, G; Fu, W; Li, J; Li, Q; Tang, X; Xiong, Y; Yao, L; You, M, 2023)
"Tranexamic acid (1 g) was administered intravenously to all patients in both study groups."1.72Use of tranexamic acid may reduce the need for routine tourniquet use in total knee arthroplasty. ( Akdoğan, BM; Akdoğan, M; Atilla, HA; Çatma, MF; Gülsoy, A; Öztürk, A, 2022)
"Tranexamic acid (TXA) has reduced blood transfusion following total hip arthroplasty (THA)."1.56Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty. ( Deckard, ER; Meneghini, RM; Wurtz, JW; Wurtz, LD; Ziemba-Davis, M, 2020)
"Thirty-four patients with haemophilia A undergoing 24 TKA and 18 THA were evaluated in this retrospective study (No."1.51Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia. ( Huang, Q; Huang, ZY; Ma, J; Pei, FX; Shen, B; Zeng, HJ; Zhou, ZK, 2019)
"Blood conservation; the area of greatest clinical variability was seen in dosing regimes for Tranexamic acid."1.37Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice. ( Bird, S; McGill, N, 2011)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.38)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's15 (35.71)24.3611
2020's26 (61.90)2.80

Authors

AuthorsStudies
Jiang, W1
Fu, M1
Dong, W1
Zhou, N1
Shen, J1
Zhang, X2
Hao, J1
Goldstein, K1
Jones, C1
Kay, J1
Shin, J1
de Sa, D1
Petersen, W1
Bentzin, M1
Bierke, S1
Park, HU1
Häner, M1
Xu, H2
Xie, J2
Yang, J1
Huang, Z2
Wang, D2
Pei, F3
Mackenzie, SP1
Spasojevic, M1
Smith, M1
Mattern, O1
Piggott, RP1
Patel, SS1
Bedaiwy, N1
Cass, B1
Young, A1
Nicholson, TA1
Kirsch, JM1
Churchill, R1
Lazarus, MD1
Abboud, JA1
Namdari, S1
Akdoğan, M1
Öztürk, A1
Çatma, MF1
Akdoğan, BM1
Gülsoy, A1
Atilla, HA1
Bildik, C3
Pehlivanoglu, T3
Li, J2
You, M1
Yao, L1
Fu, W1
Li, Q3
Chen, G1
Tang, X1
Xiong, Y1
Shen, L1
Jiang, Z1
Wang, Q1
Xu, W1
Ye, S1
Chen, M1
Luo, Y1
Zhao, C1
Kang, P1
Yu, Y1
Lin, H1
Wu, Z1
Xu, P1
Lei, Z1
Huang, ZY1
Huang, Q3
Zeng, HJ1
Ma, J3
Shen, B2
Zhou, ZK2
Pei, FX3
Taunton, MJ1
Liu, YF1
Hong, CK1
Hsu, KL1
Kuan, FC1
Chen, Y1
Yeh, ML1
Su, WR1
Lei, YT1
Xie, JW1
Huang, W2
Clarius, M1
Clarius, LM1
Wang, Y1
Zhou, A1
Wurtz, JW2
Wurtz, LD2
Ziemba-Davis, M2
Deckard, ER2
Meneghini, RM2
Ma, H1
Yao, H2
Zhang, T1
Wan, C1
Hurley, ET2
Lim Fat, D1
Pauzenberger, L2
Mullett, H1
Lei, Y1
Cui, D1
Xia, P1
Zou, X1
Huang, H1
Belk, JW1
McCarty, EC1
Houck, DA1
Dragoo, JL1
Savoie, FH1
Thon, SG1
Ma, D1
Pan, J1
Wen, L1
Fried, JW1
Bloom, DA1
Baron, SL1
Popovic, J1
Campbell, KA1
Strauss, EJ1
Jazrawi, LM1
Alaia, MJ1
Kopitkó, C1
Czermann, R1
Orosz, M1
Hangody, G1
Kiss, D1
Szabó, Z1
Hangody, L1
Domej, MA1
Heuberer, PR1
Hexel, M1
Grieb, A1
Laky, B1
Blasl, J1
Anderl, W1
Xie, X1
Li, L1
Kraus, VB1
Palanisamy, JV1
Das, S1
Moon, KH1
Kim, DH1
Kim, TK1
Yang, Y1
He, C1
Luo, ZY1
Zeng, WN1
Lemoine, A1
Lambaudie, E1
Bonnet, F1
Leblanc, E1
Alfonsi, P1
Maniar, RN1
Pradhan, P1
Bhatnagar, N1
Maniar, A1
Bidwai, R1
Bindal, P1
Tzatzairis, T1
Drosos, GI1
Vogiatzaki, T1
Tilkeridis, K1
Ververidis, A1
Kazakos, K1
Remérand, F2
Cotten, M1
N'Guessan, YF1
Couvret, C2
Rosset, P2
Favard, L1
Laffon, M2
Fusciardi, J2
Sculco, PK1
Pagnano, MW1
Serrano Mateo, L1
Goudarz Mehdikhani, K1
Cáceres, L1
Lee, YY1
Gonzalez Della Valle, A1
Yue, C1
Bird, S1
McGill, N1
Chevet, I1
Baud, A1
Pouplard, C1
Gersel-Pedersen, N1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Benefits on Post-operative Pain of Intravenous, Intraoperative, Tranexamic Acid Injection During Arthroscopic Shoulder Surgery.[NCT05302986]Phase 3220 participants (Anticipated)Interventional2023-02-24Recruiting
Effects of the Application of a New Pharmacological Protocol for Shoulder Arthroscopy in Beach Chair Position[NCT05397652]Phase 4104 participants (Actual)Interventional2021-05-24Completed
A Randomised, Prospective Evaluation on the Effectiveness of Tranexamic Acid in Reducing Postoperative Swelling and Haematoma Formation After the Latarjet Procedure.[NCT03458468]100 participants (Actual)Interventional2018-03-01Completed
Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy[NCT03954860]80 participants (Actual)Interventional2018-08-01Completed
Evaluation of the Use of Tranexamic Acid in Tibial Osteotomies: a Randomised Controlled Clinical Trial.[NCT04785651]84 participants (Anticipated)Interventional2021-02-22Recruiting
Do Peri-operative High Doses of Intravenous Glucocorticoids Improve Short-term Functional Outcome After Direct Anterior Total Hip Arthroplasty? A Randomized, Single Surgeon, Placebo Controlled, Double Blind Study[NCT04317872]70 participants (Anticipated)Interventional2020-07-01Recruiting
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application, a Comparison With Intravenous Tranexamic Acid Only in Total Hip Arthroplasty[NCT03623789]Phase 490 participants (Anticipated)Interventional2018-08-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for tranexamic acid and Pain, Postoperative

ArticleYear
Tranexamic Acid Administration in Arthroscopic Surgery Is a Safe Adjunct to Decrease Postoperative Pain and Swelling: A Systematic Review and Meta-analysis.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2022, Volume: 38, Issue:4

    Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Blood Loss, Surgical; Female; Hemarth

2022
[Fast-track arthroplasty-intra- and post-operative management].
    Der Orthopade, 2020, Volume: 49, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; I

2020
Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2021, Volume: 37, Issue:4

    Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Hemarthrosis; Humans; Knee; Lysholm K

2021
[Perioperative care of epithelial ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF a
    Gynecologie, obstetrique, fertilite & senologie, 2019, Volume: 47, Issue:2

    Topics: Analgesia, Patient-Controlled; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Carcinoma, Ova

2019

Trials

25 trials available for tranexamic acid and Pain, Postoperative

ArticleYear
Use of a Multifunctional Cocktail for Postoperative Bleeding and Pain Control in Spinal Fusion: A Randomized, Double-blind, Controlled Trial.
    Spine, 2022, 09-15, Volume: 47, Issue:18

    Topics: Analgesics, Opioid; Blood Loss, Surgical; Double-Blind Method; Hemoglobins; Humans; Pain; Pain Manag

2022
Use of tranexamic acid in medial open wedge high tibial osteotomy.
    Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:9

    Topics: Hemoglobins; Humans; Osteoarthritis, Knee; Osteotomy; Pain, Postoperative; Postoperative Complicatio

2022
Synergistic Effect of a Prolonged Combination Course of Tranexamic Acid and Dexamethasone Involving High Initial Doses in Total Knee Arthroplasty: A Randomized Controlled Trial.
    The journal of knee surgery, 2023, Volume: 36, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The effect of single-dose, preoperative intravenous tranexamic acid on early postoperative pain scores after rotator cuff repair: a double-blind, randomized controlled trial.
    Journal of shoulder and elbow surgery, 2022, Volume: 31, Issue:7

    Topics: Arthroplasty; Arthroscopy; Bursitis; Humans; Pain, Postoperative; Range of Motion, Articular; Rotato

2022
The effect of tranexamic acid for visualization on pump pressure and visualization during arthroscopic rotator cuff repair: an anonymized, randomized controlled trial.
    Journal of shoulder and elbow surgery, 2022, Volume: 31, Issue:11

    Topics: Arthroscopy; Epinephrine; Humans; Pain, Postoperative; Prospective Studies; Rotator Cuff; Rotator Cu

2022
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Arthroscopic rotator cuff repair performed with intra-articular tranexamic acid: could it provide improved visual clarity and less postoperative pain? A prospective, double-blind, randomized study of 63 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arthroscopy; Humans; Middle Aged; Pain, Postoperative; Range of Motion, Articular

2023
Topical use of tranexamic acid can reduce opioid consumption compared with intravenous use for patients undergoing primary total hip arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2023, Jun-03, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Analgesics, Opioid; Antifibrinolytic Agents; A

2023
Comparative study of carbazochrome sodium sulfonate and tranexamic acid in reducing blood loss and inflammatory response following direct anterior total hip arthroplasty: a prospective randomized controlled trial.
    International orthopaedics, 2023, Volume: 47, Issue:10

    Topics: Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgi

2023
Perioperative combined administration of tranexamic acid and dexamethasone in total knee arthroplasty-benefit versus harm?
    Medicine, 2019, Volume: 98, Issue:34

    Topics: Aged; Analgesics; Anti-Inflammatory Agents; Antiemetics; Antifibrinolytic Agents; Arthroplasty, Repl

2019
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of the Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-Blind, and Randomized Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2020, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Analgesics; Antifibrinolytic Agents; Arthroscopy; Double-Blind Method;

2020
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of the Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-Blind, and Randomized Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2020, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Analgesics; Antifibrinolytic Agents; Arthroscopy; Double-Blind Method;

2020
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of the Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-Blind, and Randomized Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2020, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Analgesics; Antifibrinolytic Agents; Arthroscopy; Double-Blind Method;

2020
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of the Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-Blind, and Randomized Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2020, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Analgesics; Antifibrinolytic Agents; Arthroscopy; Double-Blind Method;

2020
The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial.
    International orthopaedics, 2020, Volume: 44, Issue:3

    Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty,

2020
A new improvement: subperiosteal cocktail application to effectively reduce pain and blood loss after total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Jan-30, Volume: 15, Issue:1

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; Blood Loss, Sur

2020
Tranexamic acid for the Latarjet procedure: a randomized controlled trial.
    Journal of shoulder and elbow surgery, 2020, Volume: 29, Issue:5

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antifibrinolytic Agents; Blood Loss, Surgica

2020
The efficacy and safety of intravenous tranexamic acid in anterior cruciate ligament reconstruction: A randomized controlled trial protocol.
    Medicine, 2020, Aug-21, Volume: 99, Issue:34

    Topics: Anterior Cruciate Ligament Reconstruction; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tran

2020
Effects of Different Applications of Tranexamic Acid on Perioperative Blood Transfusion Rate and Postoperative Pain in Unilateral Total Knee Arthroplasty.
    Advances in therapy, 2021, Volume: 38, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2021, Volume: 37, Issue:6

    Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Autografts; Bone-Pat

2021
A randomized comparative evaluation of local infiltration analgesia, extended nerve blocks, and conventional analgesia in pain management after total knee arthroplasty.
    Joint diseases and related surgery, 2021, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local

2021
The effect of intravenous tranexamic acid on blood loss and early post-operative pain in total shoulder arthroplasty.
    The bone & joint journal, 2017, Volume: 99-B, Issue:8

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Intravenous and Topical Tranexamic Acid Alone Are Superior to Tourniquet Use for Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Dec-20, Volume: 99, Issue:24

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; China; Combine

2017
Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial.
    Thrombosis and haemostasis, 2019, Volume: 119, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2019
Role of Suction Drain after Knee Arthroplasty in the Tranexamic Acid Era: A Randomized Controlled Study.
    Clinics in orthopedic surgery, 2019, Volume: 11, Issue:1

    Topics: Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Edema; Female; H

2019
Multiple intravenous tranexamic acid doses in total knee arthroplasty without tourniquet: a randomized controlled study.
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusion; Hemoglobins; Humans; Os

2019
Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomark

2016
[Tranexamic acid reduces haematomas but not pain after total knee arthroplasty].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:1

    Topics: Aged; Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Female; Hematom

2011
Tranexamic acid in alveolar sockets in the prevention of alveolitis sicca dolorosa.
    International journal of oral surgery, 1979, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Age Factors; Alveolar Process; Contraceptives, Oral; Cyclohexanecarboxylic Acids;

1979

Other Studies

13 other studies available for tranexamic acid and Pain, Postoperative

ArticleYear
Use of tranexamic acid may reduce the need for routine tourniquet use in total knee arthroplasty.
    Joint diseases and related surgery, 2022, Volume: 33, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Female; Humans; Male; Middle Aged; P

2022
Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study.
    BMC musculoskeletal disorders, 2023, Apr-05, Volume: 24, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroscopy; Blood Loss, Surgical; Hemarthrosis; H

2023
Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia.
    BMC musculoskeletal disorders, 2019, Sep-04, Volume: 20, Issue:1

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthralgia; Arthroplasty, Replacement,

2019
What's New in Adult Reconstructive Knee Surgery.
    The Journal of bone and joint surgery. American volume, 2020, 01-15, Volume: 102, Issue:2

    Topics: Analgesics, Opioid; Anesthesia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2020
Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:6S

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2020
[A comparative study of Taylor spatial frame and unilateral external fixator in treatment of tibiofibular open fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Apr-15, Volume: 34, Issue:4

    Topics: Blood Loss, Surgical; External Fixators; Fracture Fixation, Internal; Fracture Healing; Fractures, O

2020
Letter to the Editor on "Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Pain, Postope

2020
Author Response to Commentary on "Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Pain, Postope

2020
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Tranexamic acid decreases risk of haematomas but not pain after hip arthroplasty.
    Orthopaedics & traumatology, surgery & research : OTSR, 2013, Volume: 99, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss

2013
Perioperative solutions for rapid recovery joint arthroplasty: get ahead and stay ahead.
    The Journal of arthroplasty, 2015, Volume: 30, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Clinical Protocols; Fluid Therapy; Hemorrhage; H

2015
Topical Tranexamic Acid May Improve Early Functional Outcomes of Primary Total Knee Arthroplasty.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:7

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Trans

2016
Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:1

    Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia; Anticoagulants; Antifibrinolytic Ag

2011