tranexamic acid has been researched along with Osteonecrosis in 3 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tranexamic acid (TXA) reduces surgical blood loss and alleviates inflammatory response in total hip arthroplasty." | 2.90 | Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial. ( He, C; Li, Q; Luo, ZY; Pei, FX; Wang, D; Yang, Y; Zeng, WN; Zhou, ZK, 2019) |
| "Tranexamic acid (TXA) has demonstrated efficacy in reducing blood loss, reduction in hemoglobin, and blood transfusion requirements in primary total hip arthroplasty (THA)." | 2.87 | Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study. ( Luo, ZY; Pei, FX; Wang, D; Wang, HY; Zhou, K; Zhou, ZK, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, ZY | 2 |
| Wang, HY | 1 |
| Wang, D | 2 |
| Zhou, K | 1 |
| Pei, FX | 2 |
| Zhou, ZK | 2 |
| Yang, Y | 1 |
| He, C | 1 |
| Li, Q | 1 |
| Zeng, WN | 1 |
| Zhang, Y | 1 |
| Zhang, L | 1 |
| Ma, X | 1 |
| Jia, Y | 1 |
| Wang, H | 1 |
| Zhu, Y | 1 |
| Liu, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss, Transfusion Index and Complications After Total Hip Replacement. A Prospective, Randomized, Double Blind Clinical Trial[NCT04187014] | Phase 2 | 90 participants (Actual) | Interventional | 2020-02-06 | Completed | ||
| Extended Postoperative Tranexamic Acid Use in Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial[NCT05099276] | Phase 4 | 46 participants (Actual) | Interventional | 2021-12-07 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for tranexamic acid and Osteonecrosis
| Article | Year |
|---|---|
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A | 2018 |
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A | 2018 |
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A | 2018 |
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A | 2018 |
Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial.
Topics: Administration, Oral; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo | 2019 |
What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?
Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Dose-Response | 2016 |