Page last updated: 2024-11-05

tranexamic acid and Neoplasms

tranexamic acid has been researched along with Neoplasms in 17 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" Several reports show a successful therapeutic use of the antifibrinolytic agent tranexamic acid in palliative care patients having hemorrhages."7.85Bleeding Control in Palliative Care Patients With the Help of Tranexamic Acid. ( Bardenheuer, HJ; Frankenhauser, S; Geist, MJP; Kessler, J, 2017)
" In the present case study, a new technique, using intratumoral injection of tranexamic acid to control significant bleeding during bronchoscopic biopsy, is described."7.77Bronchoscopic intratumoral injection of tranexamic acid: a new technique for control of biopsy-induced bleeding. ( Zamani, A, 2011)
"Many patients with cancer involving the respiratory system suffer from the frequent recurrence of significant, submassive hemoptysis, which may result in invasive procedures, hospital stays, and a reduction in quality of life."5.42Nebulized Tranexamic Acid as a Noninvasive Therapy for Cancer-Related Hemoptysis. ( Hankerson, MJ; Mallon, WK; Raffetto, B; Shoenberger, JM, 2015)
" Several reports show a successful therapeutic use of the antifibrinolytic agent tranexamic acid in palliative care patients having hemorrhages."3.85Bleeding Control in Palliative Care Patients With the Help of Tranexamic Acid. ( Bardenheuer, HJ; Frankenhauser, S; Geist, MJP; Kessler, J, 2017)
" In the present case study, a new technique, using intratumoral injection of tranexamic acid to control significant bleeding during bronchoscopic biopsy, is described."3.77Bronchoscopic intratumoral injection of tranexamic acid: a new technique for control of biopsy-induced bleeding. ( Zamani, A, 2011)
" Secondary outcomes were other adverse events, blood transfusion, and blood loss."2.55The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. ( Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C, 2017)
"Many patients with cancer involving the respiratory system suffer from the frequent recurrence of significant, submassive hemoptysis, which may result in invasive procedures, hospital stays, and a reduction in quality of life."1.42Nebulized Tranexamic Acid as a Noninvasive Therapy for Cancer-Related Hemoptysis. ( Hankerson, MJ; Mallon, WK; Raffetto, B; Shoenberger, JM, 2015)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's5 (29.41)24.3611
2020's6 (35.29)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Gazendam, AM1
Schneider, P1
Vélez, R1
Ghert, M1
Ackerman, RS1
Hirschi, M1
Trona, N1
Joyce, DM1
Evans, T1
Patel, SY1
Wright, GP1
Wolf, AM1
Waldherr, TL1
Ritz-Holland, D1
Laney, ED1
Chapman, HA1
Lane, BR1
Assifi, MM1
Chung, MH1
Montroy, J2
Hutton, B2
Fergusson, DA2
Tinmouth, A1
Lavallée, LT2
Cagiannos, I2
Morash, C2
Flaman, A1
Breau, RH2
Varady, NH1
Chen, AF1
Drayer, NJ1
Ready, J1
Lozano-Calderon, SA1
Hayden, BL1
Rampotas, A1
Watson, E1
Burton, K1
Hill, QA1
Pavord, S1
Fergusson, NA1
Cnossen, S1
Geist, MJP1
Kessler, J1
Frankenhauser, S1
Bardenheuer, HJ1
Hankerson, MJ1
Raffetto, B1
Mallon, WK1
Shoenberger, JM1
Zamani, A1
Laurentaci, G2
Tatò, FB2
Dunbar, SD1
Ornstein, DL1
Zacharski, LR1
Fosså, SD1
Solheim, O1
Fosså, J1
Høst, H1
Rutqvist, LE1
Bolund, C1
Friberg, S1
Einhorn, N1
Wallgren, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylactic Topical Epinephrine to Reduce Transbronchial Lung Biopsy-related Hemorrhage in Lung Transplant Recipients: a Prospective Double-blind Placebo-controlled Trial (PROPHylactic Epinephrine in Transbronchial Biopsy [PROPHET] Trial)[NCT03126968]Phase 2/Phase 3100 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for tranexamic acid and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Incidence of Thromboembolic Events in Oncology Patients Receiving Intraoperative Tranexamic Acid During Orthopedic Surgery: A Retrospective Review at a Comprehensive Cancer Center.
    A&A practice, 2020, Jan-15, Volume: 14, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Incidence; Intraoperativ

2020
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.
    Transfusion medicine reviews, 2017, Volume: 31, Issue:3

    Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans;

2017
Cancer treatment with inhibitors of urokinase-type plasminogen activator and plasmin.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:9

    Topics: Amiloride; Animals; Antineoplastic Agents; Aprotinin; Diuretics; Fibrinolysin; Humans; Neoplasms; Se

2000

Trials

2 trials available for tranexamic acid and Neoplasms

ArticleYear
Preoperative tranexamic acid does not reduce transfusion rates in major oncologic surgery: Results of a randomized, double-blind, and placebo-controlled trial.
    Journal of surgical oncology, 2020, Volume: 122, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female; Follo

2020
[Cyklokapron (tranexamic acid) in the treatment of patients with advanced neoplasms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1978, Oct-10, Volume: 98, Issue:28

    Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Eval

1978

Other Studies

11 other studies available for tranexamic acid and Neoplasms

ArticleYear
Tourniquet use in patients undergoing tumour resection and endoprosthetic reconstruction of the knee.
    The bone & joint journal, 2022, Volume: 104-B, Issue:10

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Humans; Knee Joint; Neoplasms; Tourniquets;

2022
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre.
    Current oncology (Toronto, Ont.), 2020, Volume: 27, Issue:6

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnai

2020
Tranexamic acid in patients with current or former cancer undergoing hip and knee arthroplasty.
    Journal of surgical oncology, 2021, Volume: 123, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Fema

2021
A real-world study of immune thrombocytopenia management during the COVID-19 pandemic in the UK.
    British journal of haematology, 2022, Volume: 196, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Combined M

2022
Bleeding Control in Palliative Care Patients With the Help of Tranexamic Acid.
    Journal of palliative care, 2017, Volume: 32, Issue:2

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Female; Germany; Hemorrhage; Humans; Male; Middle Aged;

2017
Nebulized Tranexamic Acid as a Noninvasive Therapy for Cancer-Related Hemoptysis.
    Journal of palliative medicine, 2015, Volume: 18, Issue:12

    Topics: Antifibrinolytic Agents; Hemoptysis; Humans; Nebulizers and Vaporizers; Neoplasms; Palliative Care;

2015
Bronchoscopic intratumoral injection of tranexamic acid: a new technique for control of biopsy-induced bleeding.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:5

    Topics: Adult; Biopsy; Bronchoscopy; Hemorrhage; Humans; Injections, Intralesional; Male; Methods; Middle Ag

2011
[Possibilities of immunostimulation in oncology. I. In vitro functional activity of rat peritoneal macrophages in presence of tranexamic acid].
    Minerva medica, 1980, Sep-22, Volume: 71, Issue:35

    Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Cells, Cultured; Cyclohexanecarboxylic Acids; In Vit

1980
[Possibilities of immunostimulation in oncology. II. Activation of peritoneal macrophages of rats treated with tranexamic acid].
    Minerva medica, 1980, Oct-06, Volume: 71, Issue:38

    Topics: Animals; Ascitic Fluid; Cells, Cultured; Cyclohexanecarboxylic Acids; Immunotherapy; Macrophages; Ne

1980
[Cyklokapron in the treatment of neoplasms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1978, Oct-10, Volume: 98, Issue:28

    Topics: Cyclohexanecarboxylic Acids; Humans; Neoplasms; Tranexamic Acid

1978
[Treatment of advanced cancer with Cyclocapron (tranexamic acid)].
    Lakartidningen, 1977, Aug-10, Volume: 74, Issue:32

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Humans; Melanoma

1977