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tranexamic acid and Necrosis

tranexamic acid has been researched along with Necrosis in 13 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Although intravascular thrombi and infarct-type necrosis have been reported in leiomyomas following tranexamic acid therapy, intratumoral vasculopathy resembling acute atherosis has not been reported to date in patients without exposure to gonadotropin receptor agonist."7.85Intratumoral Vasculopathy in Leiomyoma Treated With Tranexamic Acid. ( Krigman, HR; Kudose, S, 2017)
"Infarct-type necrosis was observed in the leiomyomas of 38 patients, 22 of whom had tranexamic acid (15%) whereas the remaining 16 had no drug exposure (4."7.74Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. ( Chan, QK; Cheung, AN; Cheung, CL; Ip, PP; Lam, KW; Pun, TC; Yeung, MC, 2007)
"Although intravascular thrombi and infarct-type necrosis have been reported in leiomyomas following tranexamic acid therapy, intratumoral vasculopathy resembling acute atherosis has not been reported to date in patients without exposure to gonadotropin receptor agonist."3.85Intratumoral Vasculopathy in Leiomyoma Treated With Tranexamic Acid. ( Krigman, HR; Kudose, S, 2017)
" Tranexamic acid (TA), an anti-fibrinolytic agent, has been shown to reduce peri-operative blood loss without increasing the risk of myocardial infarction (MI); however, no large study has examined the association between TA treatment and post-CABG myonecrosis."3.85Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery. ( Alexander, JH; Carrier, M; Lopes, RD; Merrill, PD; Podgoreanu, M; Tardif, JC; van Diepen, S, 2017)
"Infarct-type necrosis was observed in the leiomyomas of 38 patients, 22 of whom had tranexamic acid (15%) whereas the remaining 16 had no drug exposure (4."3.74Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. ( Chan, QK; Cheung, AN; Cheung, CL; Ip, PP; Lam, KW; Pun, TC; Yeung, MC, 2007)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Cochrane, AM1
Barton, KT1
Turner, MN1
Hulbert, ML1
Yozawa, S1
Ogawa, H1
Matsumoto, K1
Akiyama, H1
Raimbault, C1
Kudose, S1
Krigman, HR1
van Diepen, S1
Merrill, PD1
Carrier, M1
Tardif, JC1
Podgoreanu, M1
Alexander, JH1
Lopes, RD1
Levin, MD1
Betjes, MG1
V d Kwast, TH1
Wenberg, BL1
Leebeek, FW1
Okada, K1
Ueshima, S1
Imano, M1
Kataoka, K1
Matsuo, O1
Ip, PP1
Lam, KW1
Cheung, CL1
Yeung, MC1
Pun, TC1
Chan, QK1
Cheung, AN1
Ueda, F1
Aratani, S1
Mimura, K1
Kimura, K1
Nomura, A1
Enomoto, H1
Boutonnat, J1
Barbier, M1
Muirhead, K1
Mousseau, M1
Grunwald, D1
Ronot, X1
Seigneurin, D1
Kondo, M1
Yoshikawa, T1
Takemura, S1
Yokoe, N1
Kawai, K1
Masuda, M1
Kurebayashi, Y1
Ikeda, T1
Osada, Y1
Houwing, RH1
Leguit, P1

Reviews

1 review available for tranexamic acid and Necrosis

ArticleYear
[What's new in interventional dermatology?]
    Annales de dermatologie et de venereologie, 2018, Volume: 145 Suppl 7

    Topics: Blindness; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Dermal Fillers; Dermatology; Embolism;

2018

Other Studies

12 other studies available for tranexamic acid and Necrosis

ArticleYear
Tranexamic acid for management of gross hematuria due to renal papillary necrosis in sickle cell disease.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:10

    Topics: Anemia, Sickle Cell; Hematuria; Humans; Kidney Papillary Necrosis; Necrosis; Sickle Cell Trait; Tran

2023
Periarticular Injection of Tranexamic Acid Reduces Blood Loss and the Necessity for Allogeneic Transfusion After Total Knee Arthroplasty Using Autologous Transfusion: A Retrospective Observational Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2018
Intratumoral Vasculopathy in Leiomyoma Treated With Tranexamic Acid.
    International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 2017, Volume: 36, Issue:4

    Topics: Female; Humans; Hysterectomy; Leiomyoma; Menorrhagia; Middle Aged; Necrosis; Telangiectasia, Heredit

2017
Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery.
    Journal of thrombosis and thrombolysis, 2017, Volume: 43, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Area Under Curve; Blood Loss, Surgical; Coronary Artery Bypass; Creat

2017
Acute renal cortex necrosis caused by arterial thrombosis during treatment for acute promyelocytic leukemia.
    Haematologica, 2003, Volume: 88, Issue:6

    Topics: Acute Kidney Injury; Adult; Antifibrinolytic Agents; Antineoplastic Agents; Female; Humans; Kidney C

2003
The regulation of liver regeneration by the plasmin/alpha 2-antiplasmin system.
    Journal of hepatology, 2004, Volume: 40, Issue:1

    Topics: alpha-2-Antiplasmin; Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver I

2004
Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas.
    The American journal of surgical pathology, 2007, Volume: 31, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Humans; Infarction; Leiomyoma; Meno

2007
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric mucosal damage induced by various necrotizing agents in rats.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Electrolytes; Ethanol; Gastric Acid; Gastric J

1984
Response of chemosensitive and chemoresistant leukemic cell lines to drug therapy: simultaneous assessment of proliferation, apoptosis, and necrosis.
    Cytometry, 2000, Feb-15, Volume: 42, Issue:1

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2000
Hemorrhagic necrosis of the intestinal mucosa associated with disseminated intravascular coagulation.
    Digestion, 1978, Volume: 17, Issue:1

    Topics: Animals; Blood Coagulation Factors; Complement System Proteins; Disseminated Intravascular Coagulati

1978
Cytoprotective action of cetraxate against HCl.ethanol-induced gastric lesion in rats.
    Japanese journal of pharmacology, 1988, Volume: 46, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Ethanol; Gastric

1988
[Skin necrosis following administration of vasopressin].
    Nederlands tijdschrift voor geneeskunde, 1987, Nov-21, Volume: 131, Issue:47

    Topics: Aged; Female; Hemoptysis; Humans; Multiple Organ Failure; Necrosis; Skin; Tranexamic Acid; Vasopress

1987