Page last updated: 2024-11-05

tranexamic acid and Myocardial Infarction

tranexamic acid has been researched along with Myocardial Infarction in 31 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"Objective To summarize cases of acute myocardial infarction (AMI) after tranexamic acid (TXA) administration."9.05Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports. ( Shao, K; Yao, YT; Yuan, X, 2020)
"Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are concerns about its thromboembolic effects."7.01Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis. ( Cheah, S; Cheong, CC; Mong, SXY; Ng, KT; Tsan, SEH; Viknaswaran, NL; Wang, CY, 2023)
" The purpose of this study was to determine if TXA is safe to use in patients with a history of CAD or coronary stents."5.62Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty. ( Rozell, JC; Schwarzkopf, R; Sharan, M; Tang, A; Waren, D; Zak, SG, 2021)
"The contribution of fibrinolysis to postoperative bleeding after cardiopulmonary bypass led to routine use of tranexamic acid, a potent antifibrinolytic drug, for a period of time."5.07Tranexamic acid (Cyklokapron) is not necessary to reduce blood loss after coronary artery bypass operations. ( Abdelnoor, M; Am Holen, E; Ovrum, E; Oystese, R; Ringdal, ML, 1993)
"Objective To summarize cases of acute myocardial infarction (AMI) after tranexamic acid (TXA) administration."5.05Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports. ( Shao, K; Yao, YT; Yuan, X, 2020)
" A combination of aprotinin with tranexamic acid may be effective in preventing or delaying rebleeding after rupture of an intracerebral aneurysm; the addition of aprotinin seems to decrease the incidence of delayed cerebral vasospasm and ischaemic complications which are sometimes noted when tranexamic acid alone is used."4.77Clinical application of inhibitors of fibrinolysis. ( Verstraete, M, 1985)
" Tranexamic acid (TA), an anti-fibrinolytic agent, has been shown to reduce peri-operative blood loss without increasing the risk of myocardial infarction (MI); however, no large study has examined the association between TA treatment and post-CABG myonecrosis."3.85Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery. ( Alexander, JH; Carrier, M; Lopes, RD; Merrill, PD; Podgoreanu, M; Tardif, JC; van Diepen, S, 2017)
"The case report illustrates an acute myocardial infarction (MI) in a 41-year-old hypertensive woman possibly because of an intake of a combination of tranexamic acid and mefenamic acid for dysmenorrhoea and menorrhagia."3.79Acute MI in a young hypertensive woman: could it be due to tranexamic acid? ( Gupta, PN; Mullamalla, UR; Sabin, P; Vellappan, P, 2013)
"Factor VIII:C, epsilon amino-caproic acid or tranexamic acid are prophylactic agents used in preventing hemorrhage pre-operatively in patients with hemophilia A."3.75Acute myocardial infarction in a patient with hemophilia A and factor V Leiden mutation. ( Günaldi, M; Helvaci, A; Kiskaç, M; Küçükkaya, RD; Yildirim, ND, 2009)
" The ongoing trials create six new comparisons: tranexamic acid (tablet + injection) versus placebo; intravenous tranexamic acid versus oral tranexamic acid; topical tranexamic acid versus oral tranexamic acid; different intravenous tranexamic acid dosing regimes; topical tranexamic acid versus topical fibrin glue; and fibrinogen (injection) versus placebo."3.01Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures. ( Brunskill, SJ; Champaneria, R; Dorée, C; Estcourt, LJ; Geneen, LJ; Gibbs, VN; Novak, A; Palmer, AJ; Raval, P, 2023)
"Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are concerns about its thromboembolic effects."3.01Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis. ( Cheah, S; Cheong, CC; Mong, SXY; Ng, KT; Tsan, SEH; Viknaswaran, NL; Wang, CY, 2023)
"Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98)."2.94Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. ( , 2020)
" To date, the most efficacious dosing protocol in this setting has not yet been ascertained."1.72No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA. ( Bugbee, WD; Copp, SN; Evans, AS; Ezzet, KA; McCauley, JC; Rosen, AS; Walker, RH; Wilde, JM, 2022)
" The purpose of this study was to determine if TXA is safe to use in patients with a history of CAD or coronary stents."1.62Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty. ( Rozell, JC; Schwarzkopf, R; Sharan, M; Tang, A; Waren, D; Zak, SG, 2021)
"Tranexamic acid was effective in reducing the need for blood transfusions while not increasing the risk of complications, including thromboembolic events and renal failure."1.40Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. ( Boettner, F; Danninger, T; Mazumdar, M; Memtsoudis, SG; Opperer, M; Poeran, J; Rasul, R; Suzuki, S, 2014)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's3 (9.68)18.2507
2000's10 (32.26)29.6817
2010's9 (29.03)24.3611
2020's8 (25.81)2.80

Authors

AuthorsStudies
Wilde, JM1
Copp, SN1
Ezzet, KA1
Rosen, AS1
Walker, RH1
McCauley, JC1
Evans, AS1
Bugbee, WD1
Zhong, H1
Poeran, J2
Liu, J1
Illescas, A1
Cozowicz, C1
Memtsoudis, SG2
Lynham, R1
Preissler, S1
Lightfoot, NJ1
Coates, J1
Gibbs, VN1
Geneen, LJ1
Champaneria, R1
Raval, P1
Dorée, C1
Brunskill, SJ1
Novak, A1
Palmer, AJ1
Estcourt, LJ1
Tsan, SEH1
Viknaswaran, NL1
Cheong, CC1
Cheah, S1
Ng, KT1
Mong, SXY1
Wang, CY1
Yao, YT1
Yuan, X1
Shao, K1
Zak, SG1
Tang, A1
Sharan, M1
Waren, D1
Rozell, JC1
Schwarzkopf, R1
Myles, PS2
Smith, JA2
Kasza, J2
Silbert, B2
Jayarajah, M2
Painter, T2
Cooper, DJ2
Marasco, S2
McNeil, J2
Bussières, JS2
McGuinness, S2
Chan, MTV2
Wallace, S2
Forbes, A2
Byrne, K1
Landoni, G1
Gupta, PN1
Mullamalla, UR1
Sabin, P1
Vellappan, P1
Roberts, I2
Rasul, R1
Suzuki, S1
Danninger, T1
Mazumdar, M1
Opperer, M1
Boettner, F1
Sun, X1
Dong, Q1
Zhang, YG1
van Diepen, S1
Merrill, PD1
Carrier, M1
Tardif, JC1
Podgoreanu, M1
Alexander, JH1
Lopes, RD1
Dietrich, W1
Spannagl, M1
Boehm, J1
Hauner, K1
Braun, S1
Schuster, T1
Busley, R1
Henry, D1
Carless, P1
Fergusson, D2
Laupacis, A1
Amissah-Arthur, KN1
Groppe, M1
Scotcher, S1
Günaldi, M1
Helvaci, A1
Yildirim, ND1
Kiskaç, M1
Küçükkaya, RD1
Ker, K1
Edwards, P1
Perel, P1
Shakur, H1
Hutton, B1
Joseph, L1
Mazer, CD1
Shapiro, S1
Tinmouth, A1
Iacobellis, G2
Mangano, DT1
Tudor, IC1
Dietzel, C1
Sirker, A1
Malik, N1
Bellamy, M1
Laffan, MA1
Ovrum, E1
Am Holen, E1
Abdelnoor, M1
Oystese, R1
Ringdal, ML1
Castelli, R1
Cicardi, M1
Gardinali, M1
Zingale, LC1
Savi, C1
Munari, M1
Agostoni, A1
Levi, M1
Cromheecke, ME1
de Jonge, E1
Prins, MH1
de Mol, BJ1
Briët, E1
Büller, HR1
Lefebvre, JM1
Qanadli, SD1
Kacher, S1
Aberkane, L1
Rigaud, M1
Lacombe, P1
Rocha, P1
Ruel, MA1
Wang, F1
Bourke, ME1
Dupuis, JY1
Robblee, JA1
Keon, WJ1
Rubens, FD1
Mekontso-Dessap, A1
Collet, JP1
Lebrun-Vignes, B1
Soubrié, C1
Thomas, D1
Montalescot, G1
Verstraete, M1

Clinical Trials (21)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321]60 participants (Actual)Interventional2022-03-24Completed
Tranexamic Acid for the Treatment of Gastrointestinal Haemorrhage: an International Randomised, Double Blind Placebo Controlled Trial[NCT01658124]Phase 312,009 participants (Actual)Interventional2013-07-31Completed
The Use of Tranexamic Acid to Reduce the Need for Transfusion 1 Week Post-operatively for Hemiarthroplasty or Intramedullary Nailing Needed to Correct Acute Hip Fractures[NCT02947529]Phase 4113 participants (Actual)Interventional2015-08-31Completed
Single Centre Randomised Controlled Trial to Assess the Effect of the Addition of Twenty-four Hours of Oral Tranexamic Acid Post-operatively to a Single Intra-operative Intravenous Dose of Tranexamic Acid on Calculated Blood Loss Following Primary Hip and[NCT03690037]Phase 41,089 participants (Actual)Interventional2016-07-07Completed
Prospective Randomized Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty[NCT03359525]Phase 4114 participants (Anticipated)Interventional2017-07-01Recruiting
The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816]25 participants (Actual)Interventional2016-04-30Terminated (stopped due to Study enrollment and goals unable to be reached.)
Local Injection of Tranexamic Acid May Reduce Bleeding, Injection Pain, and Other Post-op Complications During Mohs Micrographic Surgery[NCT04630886]Early Phase 1200 participants (Anticipated)Interventional2021-06-16Enrolling by invitation
The Influence of High-Dose Aprotinin and Tranexamic Acid on Bleeding Tendency and Allogeneic Blood Transfusion in Patients Undergoing Primary Aortic Valve Replacement or Coronary Artery Revascularization[NCT00396760]Phase 3220 participants Interventional2005-01-31Active, not recruiting
Tranexamic Acid's Effects in Patients Undergoing Laparoscopic Radical Prostatectomy: a Randomized, Double-blind, Placebo-controlled Trial[NCT05816668]Phase 3122 participants (Anticipated)Interventional2023-04-30Not yet recruiting
The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery[NCT01728636]Phase 261 participants (Actual)Interventional2013-01-15Completed
Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage: A Randomized, Double-blinded, Placebo-controlled Pilot Trial[NCT03069859]Phase 231 participants (Actual)Interventional2018-03-06Active, not recruiting
IV Tranexamic Acid Prior to Hysterectomy for Reduction of Intraoperative Blood Loss: A Randomized Placebo-Controlled Trial[NCT02911831]Early Phase 171 participants (Actual)Interventional2016-11-30Completed
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty[NCT03825939]Phase 452 participants (Actual)Interventional2015-04-21Terminated (stopped due to Lack of patient enrollment due to only one surgeon that was enrolling.)
A Randomized Comparison of Two Doses of Tranexamic Acid in Open-Heart Surgery[NCT04996368]120 participants (Actual)Interventional2022-02-01Completed
A Randomized Control Trial Evaluating the Use of Topical Tranexamic Acid in Bilateral Breast Reduction Surgery to Prevent Bleeding Complications[NCT04918576]Phase 3106 participants (Anticipated)Interventional2022-08-31Not yet recruiting
Effects of Tranexamic Acid for Alloplastic Breast Reconstruction: A Randomized Control Trial[NCT04918589]Phase 3106 participants (Anticipated)Interventional2022-08-31Not yet recruiting
The Effect of Tranexamic Acid (TXA) on Blood Loss in Burn Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT03113253]Phase 4121 participants (Actual)Interventional2016-09-22Active, not recruiting
Influence of Elevated Baseline Serum Creatinine and Body Composition on Acute Kidney Injury in Cardiac Surgery - The InCreAS Trial[NCT02598271]200 participants (Actual)Observational2016-10-31Completed
The Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty[NCT01815918]Phase 460 participants (Actual)Interventional2011-02-28Completed
Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass (the OPTIMAL Study)[NCT03782350]Phase 43,079 participants (Actual)Interventional2018-12-26Completed
Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599]40 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood Transfusion Rates, Defined Nominally (Binary) as Having at Least One Transfusion

To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge

InterventionPatients with 1 or more transfusions (Number)
Tranexamic Acid2
Placebo3

Effect of Tranexamic Acid on the Total Length of Hospital Admission for a Large (350 cm2) Burn Injury

To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge

InterventionDays (Median)
Tranexamic Acid23
Placebo9

Intraoperative Blood Loss in mL

To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes

InterventionmL (Median)
Tranexamic Acid100
Placebo325

Additional Blood Products Transfused

Total additional blood products (fresh frozen plasma, cryoprecipitate, and platelets) transfused in the perioperative period measured in units. (NCT01728636)
Timeframe: 24 hours after skin incision

InterventionUnits (Mean)
Tranexamic Acid1
Placebo2

Estimated Intraoperative Blood Loss

Estimated Intraoperative blood loss in milliliters (mLs) (NCT01728636)
Timeframe: Incision to skin closure (approximately 10 hours)

InterventionMilliliters (Mean)
Tranexamic Acid1550
Placebo1600

Post Operative Major Morbidity

Number of participants who experienced arterial or venous thromboembolism, neurologic complications (including stroke, seizure,and delirium), infections, and pulmonary renal or cardiac adverse outcomes (demand ischemia, myocardial infarction or new arrhythmia) before another operative procedure or hospital discharge. (NCT01728636)
Timeframe: Time of surgery to date of discharge from hospital (average 7 days)

InterventionParticipants (Count of Participants)
Tranexamic Acid9
Placebo9

Total Operating Room Time

Total operating room time from incision to closure of incision in minutes. (NCT01728636)
Timeframe: Minutes

InterventionMinutes (Median)
Tranexamic Acid602
Placebo576

Total Red Blood Cells Transfused in the Intraoperative Period

Total red blood cells transfused in the intraoperative period in (mL). Total RBC equal packed red blood cells and cell saver infusion. (NCT01728636)
Timeframe: Intraoperative period (approximately 12 hours)

Interventionmilliliters (Median)
Tranexamic Acid1140
Placebo1460

Total Tranexamic Acid Dose (mg)

Total milligrams of intravenous tranexamic acid administered during the surgical procedure. (NCT01728636)
Timeframe: Intraoperative period

Interventionmilligrams (Median)
Tranexamic Acid1408
Placebo0

Length of Hospital Stay

Measured in Days (NCT03825939)
Timeframe: At Hospital Discharge

InterventionDays (Mean)
Intravenous Tranexamic Acid3
Intravenous Placebo3
Intravenous Tranexamic Acid Followed by Intravenous Placebo3

Plasmin-alpha-2-antiplasmin Complex (PAP), a Marker of Fibrinolysis

Study patients received 100 mg of intravenous hydrocortisone 2 h prior to surgery, and controls received normal saline. Blood samples, drawn pre-incision and at 4 h post tourniquet release, were assayed for PF1.2 and PAP (NCT01815918)
Timeframe: Baseline and up to 4 hours following surgery

,
Interventionug/L (Mean)
Baseline4 hs
Placebo623.31086.8
Treatment808.41638.6

Prothrombin Fragment (PF1.2), a Marker of Thrombin Generation

Study patients received 100 mg of intravenous hydrocortisone 2 h prior to surgery, and controls received normal saline. Blood samples, drawn pre-incision and at 4 h post tourniquet release, were assayed for PF1.2 and PAP (NCT01815918)
Timeframe: Baseline and up to 4 hours following surgery

,
InterventionpMol/L (Mean)
Baseline4s
Placebo263.6935.8
Treatment266.5615.9

Reviews

9 reviews available for tranexamic acid and Myocardial Infarction

ArticleYear
Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures.
    The Cochrane database of systematic reviews, 2023, 06-05, Volume: 6

    Topics: Arthroplasty, Replacement; Fibrinogen; Fractures, Bone; Hemorrhage; Hemostatics; Humans; Myocardial

2023
Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis.
    Anaesthesia, 2023, Volume: 78, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Thr

2023
Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2020, Mar-31, Volume: 35, Issue:1

    Topics: Adult; Aged; Blood Loss, Surgical; Female; Humans; Male; Middle Aged; Myocardial Infarction; Risk Fa

2020
Intravenous versus topical tranexamic acid in primary total hip replacement: A systemic review and meta-analysis.
    International journal of surgery (London, England), 2016, Volume: 32

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2009, Jan-20, Volume: 180, Issue:2

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Coronary Artery

2009
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies.
    BMJ (Clinical research ed.), 2012, Sep-11, Volume: 345

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2012
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Clinical application of inhibitors of fibrinolysis.
    Drugs, 1985, Volume: 29, Issue:3

    Topics: 4-Aminobenzoic Acid; Aminocaproic Acid; Angioedema; Antifibrinolytic Agents; Aprotinin; Blood Preser

1985

Trials

5 trials available for tranexamic acid and Myocardial Infarction

ArticleYear
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial.
    The Journal of thoracic and cardiovascular surgery, 2019, Volume: 157, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Coronary Th

2019
Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial.
    The Journal of thoracic and cardiovascular surgery, 2019, Volume: 157, Issue:2

    Topics: Activities of Daily Living; Aged; Antifibrinolytic Agents; Aspirin; Coronary Artery Bypass; Coronary

2019
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid (Cyklokapron) is not necessary to reduce blood loss after coronary artery bypass operations.
    The Journal of thoracic and cardiovascular surgery, 1993, Volume: 105, Issue:1

    Topics: Adult; Aged; Blood Transfusion, Autologous; Body Surface Area; Coronary Artery Bypass; Early Ambulat

1993

Other Studies

17 other studies available for tranexamic acid and Myocardial Infarction

ArticleYear
No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA.
    Clinical orthopaedics and related research, 2022, 04-01, Volume: 480, Issue:4

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2022
Tranexamic acid and perioperative myocardial infarction: a retrospective database analysis.
    British journal of anaesthesia, 2022, Volume: 129, Issue:5

    Topics: Antifibrinolytic Agents; Databases, Factual; Humans; Myocardial Infarction; Retrospective Studies; T

2022
Tranexamic Acid Use During Surgery Associated with Extension of Acute Perioperative Type 1 Myocardial Infarction: A Case Report.
    JBJS case connector, 2022, 04-01, Volume: 12, Issue:2

    Topics: Aged; Biomarkers; Female; Femoral Artery; Humans; Myocardial Infarction; Thrombosis; Tranexamic Acid

2022
Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2021, 05-19, Volume: 103, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2021
Acute MI in a young hypertensive woman: could it be due to tranexamic acid?
    BMJ case reports, 2013, May-27, Volume: 2013

    Topics: Adult; Antifibrinolytic Agents; Diagnosis, Differential; Female; Humans; Hypertension; Myocardial In

2013
Scientific letter: could tranexamic acid use in surgery reduce perioperative myocardial infarction?
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:23

    Topics: Antifibrinolytic Agents; Humans; Intraoperative Complications; Multicenter Studies as Topic; Myocard

2013
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery.
    Journal of thrombosis and thrombolysis, 2017, Volume: 43, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Area Under Curve; Blood Loss, Surgical; Coronary Artery Bypass; Creat

2017
Orbital subperiosteal hematoma after thrombolysis and anticoagulation for acute myocardial infarction.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2009, Volume: 29, Issue:3

    Topics: Accidental Falls; Acute Disease; Adult; Anticoagulants; Antifibrinolytic Agents; Craniocerebral Trau

2009
Acute myocardial infarction in a patient with hemophilia A and factor V Leiden mutation.
    Cardiology journal, 2009, Volume: 16, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Antifibrinolytic Agents; Blood Loss, Surgical; Coagulants; Coronary

2009
Combined treatment with tranexamic acid and oral contraceptive pill causes coronary ulcerated plaque and acute myocardial infarction.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:3

    Topics: Adult; Chest Pain; Contraceptives, Oral; Coronary Angiography; Coronary Vessels; Drug Therapy, Combi

2004
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
Acute myocardial infarction following tranexamic acid use in a low cardiovascular risk setting.
    British journal of haematology, 2008, Volume: 141, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Female; Humans; Myocardial Infarction; Postoperative Care; Tranexami

2008
Cardiopulmonary by-pass in a patient with acquired C1 inhibitor deficiency.
    The International journal of artificial organs, 1997, Volume: 20, Issue:3

    Topics: Aged; Anabolic Agents; Angioedema; Antifibrinolytic Agents; Aprotinin; Autoimmune Diseases; Calcium

1997
A new vascular sealant (Sealgel) to achieve rapid hemostasis after percutaneous angioplasty in anticoagulated patients: clinical feasibility and preliminary results.
    European radiology, 2001, Volume: 11, Issue:3

    Topics: Aged; Ancrod; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Animals; Anticoagul

2001
Is tranexamic acid safe in patients undergoing coronary endarterectomy?
    The Annals of thoracic surgery, 2001, Volume: 71, Issue:5

    Topics: Aged; Coronary Artery Bypass; Coronary Artery Disease; Endarterectomy; Female; Graft Occlusion, Vasc

2001
Acute myocardial infarction after oral tranexamic acid treatment initiation.
    International journal of cardiology, 2002, Volume: 83, Issue:3

    Topics: Administration, Oral; Aged; Female; Hemorrhage; Humans; Myocardial Infarction; Tranexamic Acid

2002