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tranexamic acid and Myelodysplastic Syndromes

tranexamic acid has been researched along with Myelodysplastic Syndromes in 3 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.

Research Excerpts

ExcerptRelevanceReference
"A controlled, randomized, double-blind study was performed to assess the effect of the oral antifibrinolytic agent tranexamic acid in patients with amegakaryocytic thrombocytopenia as regards their need for platelet transfusions and the number of bleeding episodes experienced."9.07Lack of efficacy of tranexamic acid in thrombocytopenic bleeding. ( Alling, D; Fricke, W; Griffith, P; Kimball, J; Klein, H, 1991)
"A controlled, randomized, double-blind study was performed to assess the effect of the oral antifibrinolytic agent tranexamic acid in patients with amegakaryocytic thrombocytopenia as regards their need for platelet transfusions and the number of bleeding episodes experienced."5.07Lack of efficacy of tranexamic acid in thrombocytopenic bleeding. ( Alling, D; Fricke, W; Griffith, P; Kimball, J; Klein, H, 1991)
"Gingival hemorrhage is recognized as a symptom of MDS, a rare group of potentially fatal hematological disorders, but it has not previously been documented as a presenting sign."2.40Gingival hemorrhage, myelodysplastic syndromes, and acute myeloid leukemia. A case report. ( Chapple, IL; Murray, JA; Saxby, MS, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fernández Lucas, M1
Liaño, F1
Navarro, JF1
Sastre, JL1
Quereda, C1
Ortuño, J1
Chapple, IL1
Saxby, MS1
Murray, JA1
Fricke, W1
Alling, D1
Kimball, J1
Griffith, P1
Klein, H1

Reviews

1 review available for tranexamic acid and Myelodysplastic Syndromes

ArticleYear
Gingival hemorrhage, myelodysplastic syndromes, and acute myeloid leukemia. A case report.
    Journal of periodontology, 1999, Volume: 70, Issue:10

    Topics: Acute Disease; Biopsy, Needle; Bone Marrow Cells; Chronic Disease; Diagnosis, Differential; Gingival

1999

Trials

1 trial available for tranexamic acid and Myelodysplastic Syndromes

ArticleYear
Lack of efficacy of tranexamic acid in thrombocytopenic bleeding.
    Transfusion, 1991, Volume: 31, Issue:4

    Topics: Anemia, Aplastic; Blood Transfusion; Hemorrhage; Humans; Myelodysplastic Syndromes; Platelet Transfu

1991

Other Studies

1 other study available for tranexamic acid and Myelodysplastic Syndromes

ArticleYear
Acute renal failure secondary to antifibrinolytic therapy.
    Nephron, 1995, Volume: 69, Issue:4

    Topics: Acute Kidney Injury; Aged; Humans; Male; Myelodysplastic Syndromes; Thrombocytopenia; Tranexamic Aci

1995