tranexamic acid has been researched along with Metrorrhagia in 12 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Metrorrhagia: Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The median number of bleeding or spotting days experienced during treatment was 25, 29, and 33 days in the three groups, respectively." | 2.78 | Management of initial bleeding or spotting after levonorgestrel-releasing intrauterine system placement: a randomized controlled trial. ( Draeby, J; Inki, P; O'Flynn, M; Schmelter, T; Sørdal, T, 2013) |
| "Tranexamic acid is a cheap, over the counter hemostatic agent with antifibrinolytic activity that can be used for management of excessive menstrual bleeding." | 2.74 | Role of a non-hormonal oral anti-fibrinolytic hemostatic agent (tranexamic acid) for management of patients with dysfunctional uterine bleeding. ( Buru, E; Diribaş, K; Gökçeoğlu, MA; Gultekin, M, 2009) |
| "The mean number of bleeding/spotting days was not significantly different between the groups (15." | 2.72 | The effect of tranexamic acid for treatment of irregular uterine bleeding secondary to Norplant use. ( Phupong, V; Sophonsritsuk, A; Taneepanichskul, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bistervels, IM | 1 |
| Scheres, LJJ | 1 |
| Hamulyák, EN | 1 |
| Middeldorp, S | 1 |
| Soper, DE | 1 |
| Sørdal, T | 1 |
| Inki, P | 1 |
| Draeby, J | 1 |
| O'Flynn, M | 1 |
| Schmelter, T | 1 |
| Bradley, LD | 1 |
| Gueye, NA | 1 |
| Zigler, RE | 1 |
| McNicholas, C | 1 |
| Roman, H | 1 |
| Loisel, C | 1 |
| Puscasiu, L | 1 |
| Sentilhes, L | 1 |
| Marpeau, L | 1 |
| Gultekin, M | 1 |
| Diribaş, K | 1 |
| Buru, E | 1 |
| Gökçeoğlu, MA | 1 |
| Deligeoroglou, E | 1 |
| Karountzos, V | 1 |
| Creatsas, G | 1 |
| Phupong, V | 1 |
| Sophonsritsuk, A | 1 |
| Taneepanichskul, S | 1 |
| Valsecchi, A | 2 |
| Dighiero, P | 1 |
| Frau, E | 1 |
| Bodaghi, B | 1 |
| Labetoulle, M | 1 |
| Offret, H | 1 |
| Cappelletti, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| International, Prospective, Double-blind, 3-arm Comparative, Randomized, Placebo-controlled Phase IV Study on the Effect of Counseling and Either Tranexamic Acid or Mefenamic Acid or Placebo, on the Management of Bleeding/Spotting in Women Using the Levon[NCT01295294] | Phase 4 | 187 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| The Use of Peri-Operative Intravenous Estrogen for the Mitigation of Ischemia Reperfusion Injury in the Setting of Renal Transplantation[NCT03663543] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2016-08-26 | Active, not recruiting | ||
| Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599] | 40 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for tranexamic acid and Metrorrhagia
| Article | Year |
|---|---|
Sex matters: Practice 5P's when treating young women with venous thromboembolism.
Topics: Adult; Anticoagulants; Contraceptives, Oral, Combined; Disease Susceptibility; Female; Heparin, Low- | 2019 |
The medical management of abnormal uterine bleeding in reproductive-aged women.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antifibrinolytic Agents; Blood Coagu | 2016 |
Unscheduled vaginal bleeding with progestin-only contraceptive use.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Contracepti | 2017 |
Abnormal uterine bleeding and dysfunctional uterine bleeding in pediatric and adolescent gynecology.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Child; Contraceptives, | 2013 |
3 trials available for tranexamic acid and Metrorrhagia
| Article | Year |
|---|---|
Management of initial bleeding or spotting after levonorgestrel-releasing intrauterine system placement: a randomized controlled trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Contraceptive Agents, Femal | 2013 |
Role of a non-hormonal oral anti-fibrinolytic hemostatic agent (tranexamic acid) for management of patients with dysfunctional uterine bleeding.
Topics: Administration, Oral; Adult; Antifibrinolytic Agents; Female; Humans; Metrorrhagia; Middle Aged; Tra | 2009 |
The effect of tranexamic acid for treatment of irregular uterine bleeding secondary to Norplant use.
Topics: Adult; Antifibrinolytic Agents; Double-Blind Method; Drug Implants; Female; Humans; Levonorgestrel; | 2006 |
5 other studies available for tranexamic acid and Metrorrhagia
| Article | Year |
|---|---|
The intrauterine device: a good thing revisited.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Antineoplastic Agents, Hormonal; B | 2013 |
[Management of menometrorrhagia in women with and without pregnancy intention: hierarchy of therapies].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral, Hormonal; Embolization, T | 2008 |
[Further notes on the topical use of tranexamic acid in the treatment of gynecological hemorrhage].
Topics: Adolescent; Adult; Aged; Cyclohexanecarboxylic Acids; Female; Hemorrhage; Humans; Metrorrhagia; Midd | 1980 |
[Central retinal artery occlusion related to ingestion of tranexamic acid].
Topics: Aged; Antifibrinolytic Agents; Female; Humans; Metrorrhagia; Retinal Artery Occlusion; Tranexamic Ac | 1996 |
[Possibilities of the use of an inhibitor of hemolysis (AMCHA), by rectal and vaginal administration, for gynecological hemorrhages].
Topics: Adolescent; Adult; Aged; Blood Coagulation Disorders; Child; Cyclohexanecarboxylic Acids; Female; He | 1975 |