tranexamic acid has been researched along with Melena in 6 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Melena: The black, tarry, foul-smelling FECES that contain degraded blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both." | 5.05 | Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983) |
| "A patient with von Willebrand's disease had recurrent gastrointestinal bleeding from angiodysplasia, with inadequate response to von Willebrand factor substitution, medical and endoscopic treatment, and resection of affected bowel." | 1.31 | Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa. ( Meijer, K; Peters, FT; van der Meer, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barer, D | 1 |
| Ogilvie, A | 1 |
| Henry, D | 1 |
| Dronfield, M | 1 |
| Coggon, D | 1 |
| French, S | 1 |
| Ellis, S | 1 |
| Atkinson, M | 1 |
| Langman, M | 2 |
| Katschinski, B | 1 |
| Logan, R | 1 |
| Davies, J | 1 |
| Faulkner, G | 1 |
| Pearson, J | 1 |
| Meijer, K | 1 |
| Peters, FT | 1 |
| van der Meer, J | 1 |
| Ostberg, HO | 1 |
| Ulfberg, J | 1 |
| Wennerholm, M | 1 |
| Zellner, K | 1 |
| Langman, MJ | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of High Dose Infusion and Low Dose Bolus Intravenous Omeprazole for Treatment of Bleeding Ulcer With Adherent Clot[NCT02536989] | Phase 4 | 40 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tranexamic acid and Melena
| Article | Year |
|---|---|
Drug treatment of haematemesis and melaena.
Topics: Hematemesis; Histamine H2 Antagonists; Humans; Melena; Somatostatin; Tranexamic Acid | 1987 |
3 trials available for tranexamic acid and Melena
| Article | Year |
|---|---|
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind | 1983 |
Prognostic factors in upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Duodenal Ulcer; Female | 1994 |
Drug treatment for haematemesis and melaena.
Topics: Clinical Trials as Topic; Duodenal Ulcer; Hematemesis; Histamine H2 Antagonists; Humans; Laser Thera | 1986 |
2 other studies available for tranexamic acid and Melena
| Article | Year |
|---|---|
Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa.
Topics: Angiodysplasia; Blood Transfusion; Combined Modality Therapy; Deamino Arginine Vasopressin; Estrogen | 2001 |
Acute gastrointestinal haemorrhage. Experience with early panendoscopy and tranexamic acid in a rural hospital.
Topics: Acute Disease; Adult; Aged; Cyclohexanecarboxylic Acids; Endoscopy; Gastrointestinal Hemorrhage; Hem | 1977 |