Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Trial | Phase | Enrollment | Study Type | Start Date | Status |
Post-Injury Platelet Biology: Mechanisms and Outcomes[NCT03682757] | | 367 participants (Actual) | Observational | 2018-09-20 | Completed |
Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339] | Phase 2 | 0 participants (Actual) | Interventional | 2022-03-31 | Withdrawn (stopped due to Challenges in recruitment) |
Randomized Study on the Topical Application of Tranexamic Acid to Wound Bed for Hemostasis in the Setting Granulating Wounds Following Mohs Micrographic Surgery[NCT04541303] | Early Phase 1 | 62 participants (Anticipated) | Interventional | 2020-10-08 | Recruiting |
The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty[NCT03795649] | | 80 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting |
A Large Randomised Placebo Controlled Trial Among Trauma Patients With, or at Risk of, Significant Haemorrhage, of the Effects of Antifibrinolytic Treatment on Death and Transfusion Requirement[NCT00375258] | Phase 3 | 20,211 participants (Actual) | Interventional | 2005-05-31 | Completed |
Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880] | Phase 4 | 25 participants (Actual) | Interventional | 2020-09-10 | Active, not recruiting |
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Article | Year |
Early Prehospital Tranexamic Acid Following Injury Is Associated With a 30-day Survival Benefit: A Secondary Analysis of a Randomized Clinical Trial.Annals of surgery, 2021, 09-01, Volume: 274, Issue:3
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Double-Blind Method; Emergency Medical Services; | 2021 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:10
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
Article | Year |
Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury?Shock (Augusta, Ga.), 2021, 01-01, Volume: 55, Issue:1
Topics: Adult; Antifibrinolytic Agents; Female; Humans; Injury Severity Score; Male; Middle Aged; Multiple O | 2021 |
Endotheliopathy of Trauma is an on-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational Study.Shock (Augusta, Ga.), 2018, Volume: 49, Issue:4
Topics: Adult; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Prospective | 2018 |
Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings.Thrombosis and haemostasis, 2014, Volume: 112, Issue:5
Topics: Adenocarcinoma; Aged; Anemia; Antifibrinolytic Agents; Antineoplastic Combined Chemotherapy Protocol | 2014 |
Algorithm-based coagulation management of catastrophic amniotic fluid embolism.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:1
Topics: Acidosis; Adult; Algorithms; Blood Coagulation Factors; Blood Component Transfusion; Cardiovascular | 2010 |
[Skin necrosis following administration of vasopressin].Nederlands tijdschrift voor geneeskunde, 1987, Nov-21, Volume: 131, Issue:47
Topics: Aged; Female; Hemoptysis; Humans; Multiple Organ Failure; Necrosis; Skin; Tranexamic Acid; Vasopress | 1987 |