tranexamic acid has been researched along with Liver Cirrhosis in 10 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of toxic epidermal necrolysis (TEN) induced by orally administered tranexamic acid in a patient with liver cirrhosis and acute rectal bleeding." | 3.79 | Tranexamic acid-induced toxic epidermal necrolysis. ( Aguado Gil, L; Idoate Gastearena, MA; Marques Martin, L; Pretel Irazabal, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Louro, J | 1 |
| Andersen, K | 1 |
| Dudaryk, R | 1 |
| Heidet, M | 1 |
| Amathieu, R | 1 |
| Audureau, E | 1 |
| Augusto, O | 1 |
| Nicolazo de Barmon, V | 1 |
| Rialland, A | 1 |
| Schmitz, D | 1 |
| Pierrang, F | 1 |
| Marty, J | 1 |
| Chollet-Xémard, C | 1 |
| Thirion, O | 1 |
| Jacob, L | 1 |
| Dibiasi, C | 1 |
| Wiegele, M | 1 |
| Gratz, J | 1 |
| Pretel Irazabal, M | 1 |
| Marques Martin, L | 1 |
| Aguado Gil, L | 1 |
| Idoate Gastearena, MA | 1 |
| Joshi, N | 1 |
| Kopec, AK | 1 |
| Towery, K | 1 |
| Williams, KJ | 1 |
| Luyendyk, JP | 1 |
| Perdigão, JP | 1 |
| de Almeida, PC | 1 |
| Rocha, TD | 1 |
| Mota, MR | 1 |
| Soares, EC | 1 |
| Alves, AP | 1 |
| Sousa, FB | 1 |
| Ickx, BE | 1 |
| van der Linden, PJ | 1 |
| Melot, C | 1 |
| Wijns, W | 1 |
| de Pauw, L | 1 |
| Vandestadt, J | 1 |
| Hut, F | 1 |
| Pradier, O | 1 |
| McCormick, PA | 1 |
| Ooi, H | 1 |
| Crosbie, O | 1 |
| Burak, KW | 1 |
| Lee, SS | 1 |
| Beck, PL | 1 |
| Maeda, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Early Administration of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding: a Multicenter, Randomized, Double Blind, Placebo-controlled Trial (Modified by amendment1)[NCT03023189] | Phase 4 | 500 participants (Anticipated) | Interventional | 2017-04-03 | Recruiting | ||
| Use of Metformin in Prevention and Treatment of Cardiac Fibrosis in PAI-1 Deficient Population[NCT05317806] | Phase 4 | 15 participants (Anticipated) | Interventional | 2022-10-10 | Active, not recruiting | ||
| Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study[NCT04846114] | 71 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tranexamic acid and Liver Cirrhosis
| Article | Year |
|---|---|
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome.
Topics: Adrenergic beta-Antagonists; Antifibrinolytic Agents; Diagnosis, Differential; Esophageal and Gastri | 2001 |
3 trials available for tranexamic acid and Liver Cirrhosis
| Article | Year |
|---|---|
Efficacy and tolerance of early administration of tranexamic acid in patients with cirrhosis presenting with acute upper gastrointestinal bleeding: a study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (the EXARHOSE study)
Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Double-Blind Method; France; Gastrointe | 2018 |
Postoperative bleeding after dental extraction in liver pretransplant patients.
Topics: Adult; Antifibrinolytic Agents; Cross-Sectional Studies; Dental Care for Chronically Ill; Female; He | 2012 |
Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation.
Topics: Adult; Aprotinin; Blood Loss, Surgical; Erythrocyte Transfusion; Female; Fibrinolysis; Hemostatics; | 2006 |
6 other studies available for tranexamic acid and Liver Cirrhosis
| Article | Year |
|---|---|
Correction of Severe Coagulopathy and Hyperfibrinolysis by Tranexamic Acid and Recombinant Factor VIIa in a Cirrhotic Patient After Trauma: A Case Report.
Topics: Aged; Antifibrinolytic Agents; Blood Coagulation; Factor VIIa; Humans; Liver Cirrhosis; Male; Recomb | 2017 |
Orthotopic liver transplantation in a patient receiving apixaban for portal vein thrombosis.
Topics: Aged; Blood Loss, Surgical; Carcinoma, Hepatocellular; Dabigatran; Humans; Infusions, Intravenous; L | 2019 |
Tranexamic acid-induced toxic epidermal necrolysis.
Topics: Aged; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male; Stevens-J | 2013 |
The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury.
Topics: 1-Naphthylisothiocyanate; Animals; Antifibrinolytic Agents; Bile Duct Diseases; Collagen Type I; Dis | 2014 |
Tranexamic acid for severe bleeding gastric antral vascular ectasia in cirrhosis.
Topics: Aged; Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Stomach | 1998 |
[A study on pathogenesis of gastric ulcer in patient with liver cirrhosis: with special reference to the gastric mucosal blood flow].
Topics: Adult; Anti-Ulcer Agents; Gastric Mucosa; Humans; Liver Cirrhosis; Middle Aged; Regional Blood Flow; | 1988 |