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tranexamic acid and Lichen Planus

tranexamic acid has been researched along with Lichen Planus in 2 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Lichen Planus: An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.

Research Excerpts

ExcerptRelevanceReference
"Oral tranexamic acid has been used in different types of hyperpigmentation disorder, including postinflammatory hyperpigmentation treatment and prevention, lichen planus pigmentosus, ashy dermatosis, and Riehl melanosis in a dose range from 250 mg per day to 1500 mg per day for a period range from 2 weeks to 6 months with variable efficacy and a good safety profile."9.41Oral tranexamic acid in the treatment of hyperpigmentation disorder beyond melasma: A review. ( Mahjoub, TT; Milibary, HH, 2023)
"Our study suggests that tranexamic acid could be an effective treatment for lichen planus pigmentosus with a good safety profile."7.96[Oral tranexamic acid in the treatment of lichen planus pigmentosus: A prospective study of 20 cases]. ( Chiheb, S; Elfetoiki, FZ; Hali, F; Skalli, H; Zenjari, L, 2020)
"Oral tranexamic acid has been used in different types of hyperpigmentation disorder, including postinflammatory hyperpigmentation treatment and prevention, lichen planus pigmentosus, ashy dermatosis, and Riehl melanosis in a dose range from 250 mg per day to 1500 mg per day for a period range from 2 weeks to 6 months with variable efficacy and a good safety profile."5.41Oral tranexamic acid in the treatment of hyperpigmentation disorder beyond melasma: A review. ( Mahjoub, TT; Milibary, HH, 2023)
"Our study suggests that tranexamic acid could be an effective treatment for lichen planus pigmentosus with a good safety profile."3.96[Oral tranexamic acid in the treatment of lichen planus pigmentosus: A prospective study of 20 cases]. ( Chiheb, S; Elfetoiki, FZ; Hali, F; Skalli, H; Zenjari, L, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Mahjoub, TT1
Milibary, HH1
Zenjari, L1
Elfetoiki, FZ1
Hali, F1
Skalli, H1
Chiheb, S1

Reviews

1 review available for tranexamic acid and Lichen Planus

ArticleYear
Oral tranexamic acid in the treatment of hyperpigmentation disorder beyond melasma: A review.
    Journal of cosmetic dermatology, 2023, Volume: 22, Issue:4

    Topics: Antifibrinolytic Agents; Humans; Hyperpigmentation; Lichen Planus; Melanosis; Tranexamic Acid; Treat

2023

Other Studies

1 other study available for tranexamic acid and Lichen Planus

ArticleYear
[Oral tranexamic acid in the treatment of lichen planus pigmentosus: A prospective study of 20 cases].
    Annales de dermatologie et de venereologie, 2020, Volume: 147, Issue:12

    Topics: Face; Female; Humans; Hyperpigmentation; Lichen Planus; Lichen Planus, Oral; Male; Middle Aged; Pros

2020