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tranexamic acid and Intracranial Aneurysm

tranexamic acid has been researched along with Intracranial Aneurysm in 52 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

ExcerptRelevanceReference
"A randomized controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, Cyklokapron; AB Kabi, Stockholm, Sweden) in the prevention of early rebleeding after the rupture of an intracranial aneurysm."9.05Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial. ( Fodstad, H; Forssell, A; Liliequist, B; Schannong, M, 1981)
"A double-blind clinical trial of tranexamic acid was carried out on 39 patients with fresh subarachnoid hemorrhage from a ruptured aneurysm."9.04Treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm with tranexamic acid: a double-blind clinical trial. ( Chandra, B, 1978)
"A randomized, controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, trans-AMCHA) in prevention of early rebleeding after proven rupture of an intracranial aneurysm."9.04Tranexamic acid in the preoperative management of ruptured intracranial aneurysms. ( Fodstad, H; Liliequist, B; Schannong, M; Thulin, CA, 1978)
"In a double-blind controlled clinical trial on 51 patients with subarachnoid hemorrhage, tranexamic acid, 4 gm per day for ten consecutive days, did not favorably affect the outcome."9.04Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial. ( de Jonge, H; Endtz, LJ; Schoen, JH; van Rossum, J; Wintzen, AR, 1977)
"Among our patients with ruptured intracranial aneurysms 149 were managed pre-operatively with a combination of tranexamic acid (AMCA), 3 gm daily, and aprotinin at an average of 400,000 KIU (Kallikrein inactivating units) daily."7.67Low-dose tranexamic acid combined with aprotinin in the pre-operative management of ruptured intracranial aneurysms. ( Guidetti, B; Pastore, FS; Rizzo, A; Spallone, A, 1987)
"The effect of tranexamic acid (TXA) on platelet function was examined in 37 patients with ruptured intracranial aneurysms."5.07The effect of tranexamic acid on bleeding time and haemostasis. ( Gill, JS; Hartley, JA; Hitchcock, ER; Menzies, SA; Rorke, E, 1991)
"One hundred patients with a verified subarachnoid haemorrhage were studied in a double blind, placebo-controlled trial at a single centre to determine the value and relative risks of tranexamic acid (TXA) in the management of ruptured intracranial aneurysms."5.06Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study. ( Hitchcock, ER; Meyer, CH; Tsementzis, SA, 1990)
"Seventy patients with subarachnoid haemorrhage due to ruptured intracranial aneurysms were managed by delayed intervention (third week) along with the prescription of antifibrinolytic drugs (tranexamic acid 6 g/daily)."5.06[Prospective trial of treating aneurysmal meningeal hemorrhage by delayed operation under cover of antifibrinolytic therapy]. ( Chabannes, J; Chazal, J; Commun, C; Irthum, B; Janny, P, 1986)
"We enrolled 479 patients with subarachnoid hemorrhage in a multicenter, randomized, double-blind, placebo-controlled trial to determine whether treatment with the antifibrinolytic agent tranexamic acid improves outcome by preventing rebleeding."5.05Antifibrinolytic treatment in subarachnoid hemorrhage. ( Cheah, F; Hijdra, A; Lindsay, KW; Muizelaar, JP; Murray, GD; Schannong, M; Teasdale, GM; van Crevel, H; van Gijn, J; Vermeulen, M, 1984)
"A randomized controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, Cyklokapron; AB Kabi, Stockholm, Sweden) in the prevention of early rebleeding after the rupture of an intracranial aneurysm."5.05Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial. ( Fodstad, H; Forssell, A; Liliequist, B; Schannong, M, 1981)
"The outcome of treatment with an antifibrinolytic agent (tranexamic acid) for six weeks after rupture of an intracranial aneurysm was assessed in a randomised controlled trial."5.04Prolonged antifibrinolysis: an effective non-surgical treatment for ruptured intracranial aneurysms? ( Maurice-Williams, RS, 1978)
"A double-blind clinical trial of tranexamic acid was carried out on 39 patients with fresh subarachnoid hemorrhage from a ruptured aneurysm."5.04Treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm with tranexamic acid: a double-blind clinical trial. ( Chandra, B, 1978)
"A randomized, controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, trans-AMCHA) in prevention of early rebleeding after proven rupture of an intracranial aneurysm."5.04Tranexamic acid in the preoperative management of ruptured intracranial aneurysms. ( Fodstad, H; Liliequist, B; Schannong, M; Thulin, CA, 1978)
"In a double-blind controlled clinical trial on 51 patients with subarachnoid hemorrhage, tranexamic acid, 4 gm per day for ten consecutive days, did not favorably affect the outcome."5.04Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial. ( de Jonge, H; Endtz, LJ; Schoen, JH; van Rossum, J; Wintzen, AR, 1977)
"To prevent and treat the ischemic complications due to the vasospasm, this report suggest the management of aneurysmal subarachnoid haemorrhage by the association of antifibrinolytics (tranexamic acid) to lower the risk of rebleeding, calcium channel blockers (nimodipine), and the keeping of an effective total blood volume (thanks to volume expansion and dopamine)."3.68[Evaluation of the treatment of aneurysmal meningeal hemorrhage with antifibrinolytic agents, calcium inhibitors and maintenance of effective blood volume]. ( Berard, JP; Cavaroc, G; Greil, P; Gutknecht, JL; Halberstadt, J; Irthum, B; Planchon, E, 1990)
"Among our patients with ruptured intracranial aneurysms 149 were managed pre-operatively with a combination of tranexamic acid (AMCA), 3 gm daily, and aprotinin at an average of 400,000 KIU (Kallikrein inactivating units) daily."3.67Low-dose tranexamic acid combined with aprotinin in the pre-operative management of ruptured intracranial aneurysms. ( Guidetti, B; Pastore, FS; Rizzo, A; Spallone, A, 1987)
"We previously reported that epsilon-aminocaproic acid (EACA) prolonged the bleeding time in patients with intracranial aneurysms when given in doses of 36 to 48 gm/day."3.67Clinical and laboratory investigation of the effects of epsilon-aminocaproic acid on hemostasis. ( Atkinson, AJ; Cerullo, L; Cohen, I; Green, D; Ruo, TI; Ts'ao, CH, 1985)
"Six patients with recently ruptured intracranial aneurysms were treated preoperatively with tranexamic acid (AMCA)."3.66Determination of tranexamic acid (AMCA) and fibrin/fibrinogen degradation products in cerebrospinal fluid after aneurysmal subarachnoid haemorrhage. ( Fodstad, H; Pilbrant, A; Schannong, M; Strömberg, S, 1981)
"The occurrence of cerebral ischemia and other complications were recorded, and the effects of treatment were related to the clinical condition on admission."2.69Antifibrinolytic treatment in subarachnoid hemorrhage: a randomized placebo-controlled trial. STAR Study Group. ( Roos, Y, 2000)
"Cerebral ischemia was treated with vigorous plasma volume expansion under intermittent monitoring of pulmonary wedge pressure, cardiac output, and arterial blood pressure, aiming for a hematocrit of 0."1.30Impact of medical treatment on the outcome of patients after aneurysmal subarachnoid hemorrhage. ( Avezaat, CJ; Bijvoet, HW; Hasan, D; Vermeij, FH, 1998)
"An aneurysm-induced hydrocephalus was observed in two series of patients who were treated antifibrinolytically in different ways: A = 3 g/day of AMCA + 3 - 400,000 KIU/day of aprotinins, B = 6 g/day of AMCA."1.27Hydrocephalus following aneurysmal SAH. ( Gagliardi, FM; Spallone, A, 1983)
" The last 20 patients of the present series have been treated with very low doses of AMCA associated with parotid kallikrein inhibitor (Trasylol); this dosage has been effective in preventing recurrence and has appeared to be freer from severe side effects."1.26The use of antifibrinolytic drugs in aneurysmal subarachnoid hemorrhage. ( Schisano, G, 1978)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199035 (67.31)18.7374
1990's7 (13.46)18.2507
2000's5 (9.62)29.6817
2010's3 (5.77)24.3611
2020's2 (3.85)2.80

Authors

AuthorsStudies
Kawada, T1
Tsai, KC1
Wu, YH1
Ho, MP1
Baharoglu, MI1
Germans, MR1
Rinkel, GJ1
Algra, A1
Vermeulen, M5
van Gijn, J4
Roos, YB1
Larsen, CC1
Eskesen, V1
Hauerberg, J1
Olesen, C1
Romner, B1
Astrup, J1
Nakaigawa, N1
Kamata, K1
Komatsu, R1
Ozaki, M1
Lanzino, G1
Wang, H1
Iplikçioglu, AC1
Bek, S1
Schisano, G2
Nina, P1
Roos, Y2
Guidetti, B2
Spallone, A3
Aiba, T1
Lindsay, KW3
Murray, GD3
Cheah, F1
Hijdra, A2
Muizelaar, JP2
Schannong, M4
Teasdale, GM2
van Crevel, H2
Meyer, CH3
Lowe, D1
Meyer, M1
Richardson, PL1
Neil-Dwyer, G3
Gagliardi, FM1
Sharp, MM1
Sharr, MM1
Yamaura, A1
Nakamura, T1
Makino, H1
Hagihara, Y1
Fodstad, H7
Forssell, A2
Liliequist, B3
Ramirez-Lassepas, M1
Mendelow, AD1
Stockdill, G1
Steers, AJ1
Hayes, J1
Gillingham, FJ1
Maurice-Williams, RS3
Nilsson, IM1
Pilbrant, A1
Strömberg, S1
Gordon, YB1
Sykes, A1
Alvarez Garijo, JA1
Vilches, JJ1
Aznar, JA1
Adams, HP1
Nibbelink, DW1
Torner, JC2
Sahs, AL1
Larsson, C1
Rönnberg, J1
Vermeij, FH1
Hasan, D2
Bijvoet, HW1
Avezaat, CJ1
Stroobandt, G1
Lambert, O1
Menard, E1
Watanabe, H1
Ito, M1
Chigasaki, H1
Ishii, S1
Chandra, B1
Thulin, CA1
Van Rossum, J2
Wintzen, AR2
Endtz, LJ1
Schoen, JH1
de Jonge, H1
Check, W1
Tovi, D1
Tamaki, N1
Kusunoki, T1
Oi, S1
Taomoto, K1
Matsumoto, S1
Tsementzis, SA2
Hitchcock, ER3
Menzies, SA1
Hartley, JA1
Rorke, E1
Gill, JS1
Gutknecht, JL1
Irthum, B2
Cavaroc, G1
Halberstadt, J1
Planchon, E1
Greil, P1
Berard, JP1
Pastore, FS1
Rizzo, A1
Wijdicks, EF1
Brouwers, PJ1
Hatfield, R1
Green, D1
Ts'ao, CH1
Cerullo, L1
Cohen, I1
Ruo, TI1
Atkinson, AJ1
Kassell, NF1
Haley, EC1
Chazal, J1
Commun, C1
Chabannes, J1
Janny, P1

Reviews

4 reviews available for tranexamic acid and Intracranial Aneurysm

ArticleYear
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage.
    The Cochrane database of systematic reviews, 2013, Aug-30, Issue:8

    Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Confidence Interva

2013
[The timing of surgical treatment for ruptured intracranial aneurysms--from the viewpoint of intentionally delayed operation (author's transl)].
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:8

    Topics: Cerebral Hemorrhage; Fibrinolysis; Hemostasis; Humans; Intracranial Aneurysm; Methods; Rupture, Spon

1981
Antifibrinolytic therapy in subarachnoid hemorrhage caused by ruptured intracranial aneurysm.
    Neurology, 1981, Volume: 31, Issue:3

    Topics: Aminocaproates; Aminocaproic Acid; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Ruptu

1981
The association of tranexamic acid and nimodipine in the pre-operative treatment of ruptured intracranial aneurysms.
    Acta neurochirurgica, 1998, Volume: 140, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Antihypertensive Agents

1998

Trials

17 trials available for tranexamic acid and Intracranial Aneurysm

ArticleYear
Antifibrinolytic treatment in subarachnoid hemorrhage.
    The New England journal of medicine, 1984, Aug-16, Volume: 311, Issue:7

    Topics: Cerebral Angiography; Cerebral Infarction; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Do

1984
Tranexamic acid (AMCA) in aneurysmal subarachnoid haemorrhage.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1980, Volume: 14

    Topics: Adult; Aged; Brain Ischemia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Fibrin F

1980
Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial.
    Neurosurgery, 1981, Volume: 8, Issue:2

    Topics: Adult; Aged; Brain Ischemia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Humans;

1981
Double-blind trial of aspirin in patient receiving tranexamic acid for subarachnoid hemorrhage.
    Acta neurochirurgica, 1982, Volume: 62, Issue:3-4

    Topics: Angiography; Aphasia; Aspirin; Double-Blind Method; Female; Hemiplegia; Humans; Intracranial Aneurys

1982
Coagulation and fibrinolysis in blood and cerebrospinal fluid after aneurysmal subarachnoid haemorrhage: effect of tranexamic acid (AMCA).
    Acta neurochirurgica, 1981, Volume: 56, Issue:1-2

    Topics: Adult; Aged; Blood Coagulation; Cyclohexanecarboxylic Acids; Female; Fibrin Fibrinogen Degradation P

1981
CT assessment of subarachnoid haemorrhage. A comparison between different CT methods of grading subarachnoid haemorrhage.
    British journal of neurosurgery, 1995, Volume: 9, Issue:1

    Topics: Aneurysm, Ruptured; Cerebral Angiography; Humans; Intracranial Aneurysm; Ischemic Attack, Transient;

1995
Antifibrinolytic treatment in subarachnoid hemorrhage: a randomized placebo-controlled trial. STAR Study Group.
    Neurology, 2000, Jan-11, Volume: 54, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Brain Ischemia; Calcium Channel Blockers; Drug Therapy, Combin

2000
Prolonged antifibrinolysis: an effective non-surgical treatment for ruptured intracranial aneurysms?
    British medical journal, 1978, Apr-15, Volume: 1, Issue:6118

    Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Recurrence; Ru

1978
Treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm with tranexamic acid: a double-blind clinical trial.
    Annals of neurology, 1978, Volume: 3, Issue:6

    Topics: Adult; Aged; Aminocaproic Acid; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind

1978
Tranexamic acid in the preoperative management of ruptured intracranial aneurysms.
    Surgical neurology, 1978, Volume: 10, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Clinical Trials as Topic; Constriction, Pathologic; Cyclohexan

1978
Antifibrinolytic agents for ruptured intracranial aneurysms.
    British medical journal, 1978, Aug-19, Volume: 2, Issue:6136

    Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Humans; Intracranial Ane

1978
Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial.
    Annals of neurology, 1977, Volume: 2, Issue:3

    Topics: Aged; Cerebral Angiography; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Meth

1977
Cerebral blood flow in patients with a subarachnoid haemorrhage during treatment with tranexamic acid.
    Neurochirurgia, 1992, Volume: 35, Issue:3

    Topics: Adult; Blood Flow Velocity; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Double-Bl

1992
The effect of tranexamic acid on bleeding time and haemostasis.
    Neurochirurgia, 1991, Volume: 34, Issue:5

    Topics: Bleeding Time; Blood Coagulation Tests; Drug Administration Schedule; Hemostasis; Humans; Infusions,

1991
Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study.
    Acta neurochirurgica, 1990, Volume: 102, Issue:1-2

    Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials as Topic; Cyclohexanecarbo

1990
Outcome of aneurysmal subarachnoid hemorrhage in patients 66 years of age and older.
    Clinical neurology and neurosurgery, 1988, Volume: 90, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Cerebral Infarction; Cyclohexanecarboxylic Acids; Double-Blind

1988
[Prospective trial of treating aneurysmal meningeal hemorrhage by delayed operation under cover of antifibrinolytic therapy].
    Neuro-Chirurgie, 1986, Volume: 32, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Humans; Intracranial Ane

1986

Other Studies

31 other studies available for tranexamic acid and Intracranial Aneurysm

ArticleYear
Efficacy and safety of tranexamic acid for aneurysmal subarachnoid hemorrhage.
    The American journal of emergency medicine, 2022, Volume: 57

    Topics: Antifibrinolytic Agents; Humans; Intracranial Aneurysm; Subarachnoid Hemorrhage; Tranexamic Acid

2022
Comment on: Tranexamic acid for aneurysmal subarachnoid hemorrhage.
    The American journal of emergency medicine, 2022, Volume: 59

    Topics: Humans; Intracranial Aneurysm; Subarachnoid Hemorrhage; Tranexamic Acid

2022
Considerable delay in diagnosis and acute management of subarachnoid haemorrhage.
    Danish medical bulletin, 2010, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Delayed Dia

2010
[Perioperative management of a patient complicated with Quincke's edema].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:4

    Topics: Aneurysm, Ruptured; Angioedema; Chlorpheniramine; Craniotomy; Humans; Intracranial Aneurysm; Intubat

2010
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Antifibrinolytic Agents; Glasgow Outcome Scale; Humans; Intracranial Aneurysm; Multicenter Studies a

2003
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Antifibrinolytic Agents; Glasgow Outcome Scale; Humans; Intracranial Aneurysm; Multicenter Studies a

2003
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Critical Pathways; Dose-Response Relationship, Drug; Dr

2003
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Brain Ischemia; Glasgow Outcome Scale; Humans; Intracra

2003
The role of antifibrinolytic therapy in the preoperative management of recently ruptured intracranial aneurysms.
    Surgical neurology, 1981, Volume: 15, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Cyclohexanecarboxylic Acids; Female; Humans; Intracranial

1981
Progressive change in cerebral blood flow during the first three weeks after subarachnoid hemorrhage.
    Neurosurgery, 1983, Volume: 12, Issue:1

    Topics: Adult; Aged; Aging; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Humans; Int

1983
Hydrocephalus following aneurysmal SAH.
    Zentralblatt fur Neurochirurgie, 1983, Volume: 44, Issue:2

    Topics: Apoproteins; Drug Therapy, Combination; Humans; Hydrocephalus; Intracranial Aneurysm; Intracranial P

1983
Ruptured intracranial aneurysms.
    Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:9

    Topics: Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Subarachnoi

1983
Ruptured intracranial aneurysms.
    Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:4

    Topics: Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Rupture, Sp

1983
Cerebral complication of antifibrinolytic therapy in the treatment of ruptured intracranial aneurysm. Animal experiment and a review of literature.
    European neurology, 1980, Volume: 19, Issue:2

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Blood Pressure; Cerebral Cortex; Cisterna Magna; Cyclohe

1980
Ruptured intracranial aneurysms: has the incidence of early rebleeding been over-estimated?
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:9

    Topics: Cerebral Angiography; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Middle Aged; Recurr

1982
Determination of tranexamic acid (AMCA) and fibrin/fibrinogen degradation products in cerebrospinal fluid after aneurysmal subarachnoid haemorrhage.
    Acta neurochirurgica, 1981, Volume: 58, Issue:1-2

    Topics: Adult; Biotransformation; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Fibrin

1981
Monitoring fibrinolytic activity in the cerebrospinal fluid after aneurysmal subarachnoid haemorrhage: a guide to the risk of rebleeding?
    Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:2

    Topics: Brain Neoplasms; Fibrin Fibrinogen Degradation Products; Hemangioma; Humans; Intracranial Aneurysm;

1980
Preoperative treatment of ruptured intracranial aneurysms with tranexamic acid and monitoring of fibrinolytic activity.
    Journal of neurosurgery, 1980, Volume: 52, Issue:4

    Topics: Aminocaproic Acid; Cyclohexanecarboxylic Acids; Fibrin Fibrinogen Degradation Products; Humans; Intr

1980
Antifibrinolytic therapy in patients with aneurysmal subarachnoid hemorrhage. A report of the cooperative aneurysm study.
    Archives of neurology, 1981, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Aminocaproates; Child; Cyclohexanecarboxylic Acids; Humans; Intracranial An

1981
Impact of medical treatment on the outcome of patients after aneurysmal subarachnoid hemorrhage.
    Stroke, 1998, Volume: 29, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Brain Ischemia; Female; Hemorrhage; Humans; Hydrocephalus; Int

1998
Antifibrinolytic therapy in ruptured intracranial aneurysm through repeated monitoring of fibrinolytic activity of blood.
    Neurologia medico-chirurgica, 1976, Volume: 16, Issue:PT1

    Topics: Cyclohexanecarboxylic Acids; Fibrinolysis; Humans; Intracranial Aneurysm; Rupture, Spontaneous; Suba

1976
Spontaneous thrombosis of ruptured intracranial aneurysms during treatment with tranexamic acid (AMCA). Report of three cases.
    Acta neurochirurgica, 1979, Volume: 49, Issue:3-4

    Topics: Adult; Antifibrinolytic Agents; Female; Humans; Intracranial Aneurysm; Intracranial Embolism and Thr

1979
What about medical therapy alone?
    JAMA, 1978, Nov-10, Volume: 240, Issue:20

    Topics: Antifibrinolytic Agents; Cerebral Hemorrhage; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneu

1978
The use of antifibrinolytic drugs in aneurysmal subarachnoid hemorrhage.
    Surgical neurology, 1978, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aged; Aminocaproates; Aminocaproic Acid; Cyclohexanecarboxylic Acids; Humans; Int

1978
Proceedings: Preoperative management of patients with aneurysmal subarachnoid haemorrhage. A preliminary comparative study of consecutive and randomized series.
    Acta neurochirurgica, 1975, Volume: 31, Issue:3-4

    Topics: Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Recurrence; Subarachnoid Hemorrhage; Tra

1975
[Clinical study on rebleeding of cerebral anuerysms--with special references to the warning signs of rebleeding and antifibrinolytic treatment during waiting time for surgery (author's transl)].
    No shinkei geka. Neurological surgery, 1975, Volume: 3, Issue:8

    Topics: Adult; Age Factors; Aged; Blood Pressure; Female; Humans; Hypnotics and Sedatives; Intracranial Aneu

1975
[Evaluation of the treatment of aneurysmal meningeal hemorrhage with antifibrinolytic agents, calcium inhibitors and maintenance of effective blood volume].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1990, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Cerebral Arterial Diseases; Child; Child, Preschool; Clinical Protocols; Fe

1990
Low-dose tranexamic acid combined with aprotinin in the pre-operative management of ruptured intracranial aneurysms.
    Neurochirurgia, 1987, Volume: 30, Issue:6

    Topics: Adult; Aprotinin; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Dose-Response Relationship

1987
Short-term tranexamic acid treatment in aneurysmal subarachnoid hemorrhage.
    Stroke, 1989, Volume: 20, Issue:12

    Topics: Cerebral Angiography; Cyclohexanecarboxylic Acids; Humans; Intracranial Aneurysm; Prospective Studie

1989
Clinical and laboratory investigation of the effects of epsilon-aminocaproic acid on hemostasis.
    The Journal of laboratory and clinical medicine, 1985, Volume: 105, Issue:3

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Aorta, Thoracic; Bleeding Time; Blood Platelets; Cattle;

1985
Antifibrinolytic therapy in the treatment of aneurysmal subarachnoid hemorrhage.
    Clinical neurosurgery, 1986, Volume: 33

    Topics: 4-Aminobenzoic Acid; Aminocaproates; Antifibrinolytic Agents; Humans; Intracranial Aneurysm; para-Am

1986