tranexamic acid and Intertrochanteric Fractures studies

Research Excerpts

Excerpt	Relevance	Reference
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."	9.41	The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."	9.41	Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."	9.41	[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"Local administration of tranexamic acid is associated with a reduced total blood loss, postoperative hemoglobin decline, and transfusion requirements in patients with intertrochanteric fractures."	8.95	Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."	7.11	A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."	7.01	Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."	6.90	Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
" There were no complications or adverse effects related to the evaluated interventions."	6.90	Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."	5.41	The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."	5.41	Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."	5.41	[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"Local administration of tranexamic acid is associated with a reduced total blood loss, postoperative hemoglobin decline, and transfusion requirements in patients with intertrochanteric fractures."	4.95	Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"To determine whether locally injected tranexamic acid (TXA) used in the surgical treatment of fragility hip fractures can lower transfusion rates without increasing the risk of complications."	4.12	Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review. ( Davis, S; Kumar, M; Shearier, E; Solomito, MJ; Witmer, D, 2022)
"The aim of this pre and post interventional study looks at the effects of intravenous administration of tranexamic acid on induction for elderly patients undergoing hemiarthroplasty or intramedullary nail fixation for hip fractures."	4.02	The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role? ( Chakravarty, D; Guhan, B; Kanthasamy, S; Parker, MJ, 2021)
"The specific method and dose of tranexamic acid (TXA) topically applied for intertrochanteric fractures have not been well established."	4.02	Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA. ( He, J; Huang, T; Wei, H; Xia, M; Xian, S; Xiao, Q; Xu, W, 2021)
"We investigated the clinical application of auricular point sticking (APS) combined with tranexamic acid in perioperative hemostasis in elderly patients with intertrochanteric fractures of the femur."	3.91	Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur. ( Er, Z; Yin, C; Zhang, J, 2019)
"Geriatric hip fracture patients are particularly susceptible to blood loss and venous thromboembolism (VTE) during hemiarthroplasty, yet relatively few studies have examined the safety and efficacy of tranexamic acid (TXA) in these patients."	3.91	Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study. ( Chen, G; Hu, Q; Huang, Q; Pei, F; Xie, J; Zhou, Z, 2019)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."	3.11	A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Elderly patients with intertrochanteric fractures exhibit post-traumatic hidden blood loss (HBL)."	3.01	Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial. ( Chen, X; He, T; Li, M; Liu, L; Liu, X; Long, X; Ma, H; Wang, H; Wang, W; Xu, Z, 2021)
"Osteoporotic hip fractures are a major health problem in developed countries."	3.01	Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis. ( Leverett, GD; Marriott, A, 2023)
"Anemia is one of the most common complications after hip fracture surgery."	3.01	Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. ( Augustinus, S; Gardenbroek, TJ; Goslings, JC; Mulders, MAM, 2023)
"Tranexamic acid was given intravenously or topically during the perioperative period."	3.01	Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews. ( Estcourt, LJ; Griffin, XL; Lewis, SR; Pritchard, MW; Stanworth, SJ, 2023)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."	3.01	Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."	2.90	Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
" There were no complications or adverse effects related to the evaluated interventions."	2.90	Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"Eligible patients with trochanteric fractures surgically treated by dynamic hip screw and proximal anti-rotating intramedullary nail between March 2016 and October 2017 were enrolled in the study."	2.90	Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial. ( Chen, F; Jiang, Z; Li, M; Zhu, X, 2019)
"This meta-analysis provides strong evidence that TXA is a safe and effective agent to reduce perioperative blood loss in hip fracture surgery."	2.82	Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials. ( Antoniou, G; Masouros, P; Nikolaou, VS, 2022)
" Then, subgroup and meta-regression analyses were conducted to disclose the influence of geographic area, fracture type, administration route, frequency and dosage of TXA, blood transfusion threshold, and follow-up duration on the overall effect."	2.82	Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice. ( Deng, S; Liang, J; Liu, W, 2022)
"Tranexamic acid (TXA) use has expanded across many surgical specialties."	2.72	The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries. ( Adams, JD; Marshall, WA, 2021)
"Tranexamic acid (TXA) has been widely used to decrease blood loss and transfusion rates in joint replacement surgery."	2.55	Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2017)
"Tranexamic acid (TXA) has long been the antifibrinolytic hemostatic drug of choice for orthopedic surgery."	1.91	Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs. ( Haibier, A; Qin, Q; Ran, J; Ren, Z; Yusufu, A; Zhang, Z; Zhou, Y, 2023)
"The use of tranexamic acid is effective in reduction of blood loss and rates of blood transfusion, without an apparent increase in adverse thromboembolic events."	1.72	Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients. ( AlSumadi, M; Ashour, R; Banim, R; Kharma, L; Mahmood, A; Whittam, D, 2022)
"Tranexamic acid (TXA) has shown to significantly reduce perioperative blood loss in elective orthopedic joint replacement surgery but is yet not implemented in acute hip fracture surgery for elderly patients who are particularly vulnerable to perioperative blood loss and postoperative anemia."	1.72	Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients. ( de Jong, L; Kuijper, TM; Roukema, GR; van Rijckevorsel, VAJIM, 2022)
"Tranexamic acid was used less often in the CTHA group (p < 0."	1.72	Conversion total hip arthroplasty for early failure following unstable intertrochanteric hip fracture: what can patients expect? ( Egol, KA; Penev, A; Schultz, BJ; Schwarzkopf, R; Sicat, C, 2022)
"Tranexamic acid (TXA) is a drug used to control hemorrhage by preventing the breakdown of fibrin."	1.62	The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery. ( Egol, KA; Littlefield, CP; Perskin, CR; Umeh, U; Wang, C, 2021)
" Thus, we conclude that it is safe to use TXA in this patient group."	1.62	Is tranexamic acid use in patients with a hip fracture safe? ( Andersen, LR; Clemmensen, SB; Gundtoft, PH; Halekoh, U; Lauritsen, J; Madsen, CF; Overgaard, S; Pedersen, L; Schønnemann, JO; Titlestad, K; Viberg, B, 2021)
" Our study indicates that the local administration of TXA/DEP is safe and more effective than the administration of TXA alone in treating trochanteric femoral fractures."	1.56	Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures. ( Hu, Y; Xie, L; Xu, X; Yu, H, 2020)
"Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general trauma patients as well as patients undergoing elective orthopaedic surgery."	1.43	Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients. ( Flores, E; Garner, MR; Gausden, EB; Levack, A; Lorich, DG; Nellestein, AM; Tedore, T; Warner, SJ, 2016)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective lower limb arthroplasty surgery."	1.42	The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study. ( Edmondson, M; Freeman, R; Lee, C; Rogers, BA, 2015)

Research

Studies (77)

Authors

Clinical Trials (15)

Trial Overview

Trial Outcomes

Allogenic Blood Transfusion Rates

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	23 (29.87)	24.3611
2020's	54 (70.13)	2.80

Authors	Studies
Schultz, BJ	1
Sicat, C	1
Penev, A	1
Schwarzkopf, R	1
Egol, KA	2
Masouros, P	3
Antoniou, G	1
Nikolaou, VS	3
Liu, W	1
Deng, S	1
Liang, J	1
Yee, DK	1
Wong, JSH	1
Fang, E	1
Wong, TM	1
Fang, C	1
Leung, F	1
Liu, J	2
Lei, Y	2
Liao, J	2
Liang, X	2
Hu, N	2
Huang, W	2
van Rijckevorsel, VAJIM	1
Roukema, GR	1
Kuijper, TM	1
de Jong, L	1
Cui, Y	1
Lu, Y	1
Huang, Q	2
Zhang, C	1
Sun, L	1
Ren, C	1
Wang, Q	1
Ma, T	1
Li, Z	1
Zhang, K	2
Wang, Z	2
Xue, H	1
Leverett, GD	1
Marriott, A	1
Porter, SB	2
Spaulding, AC	2
Duncan, CM	2
Wilke, BK	2
Pagnano, MW	2
Abdel, MP	2
Cornell, C	1
Fenwick, A	1
Antonovska, I	1
Pfann, M	1
Mayr, J	1
Wiedl, A	1
Nuber, S	1
Förch, S	1
Mayr, E	1
Kim, CH	1
Hwang, J	1
Lee, SJ	1
Yoon, PW	1
Yoon, KS	1
Sen, RK	1
Attar, MU	1
Saini, G	1
Tripathy, SK	1
Tekin, SB	1
Demir, IH	1
Bozgeyik, B	1
Mert, A	1
Miangul, S	1
Oluwaremi, T	1
El Haddad, J	1
Adra, M	1
Pinnawala, N	1
Nakanishi, H	1
Matar, RH	1
Than, CA	1
Stewart, TM	1
Ekinci, M	1
Ok, M	1
Ersin, M	1
Günen, E	1
Kocazeybek, E	1
Sırma, SÖ	1
Yılmaz, M	1
Agius, C	3
Cole, E	3
Mifsud, MG	3
Vasireddy, A	3
Augustinus, S	2
Mulders, MAM	2
Gardenbroek, TJ	2
Goslings, JC	2
Zhang, J	3
Fan, X	2
Zheng, Y	2
Wu, J	2
Yuan, X	2
Bloom, DA	1
Lin, CC	1
Manzi, JE	1
Mojica, ES	1
Telgheder, ZL	1
Chapman, CB	1
Konda, SR	1
Lewis, SR	1
Pritchard, MW	1
Estcourt, LJ	1
Stanworth, SJ	1
Griffin, XL	1
Yusufu, A	1
Haibier, A	1
Ren, Z	1
Qin, Q	1
Zhang, Z	1
Zhou, Y	1
Ran, J	1
Lasocki, S	2
Capdevila, X	1
Vielle, B	2
Bijok, B	1
Lahlou-Casulli, M	2
Collange, V	2
Grillot, N	1
Danguy des Deserts, M	2
Duchalais, A	2
Delannoy, B	1
Drugeon, B	2
Bouzat, P	2
David, JS	2
Rony, L	1
Loupec, T	2
Léger, M	2
Rineau, E	2
Kenmegne, GR	1
Zou, C	1
Lin, Y	1
Yin, Y	1
Huang, S	1
Banneyake, EL	1
Gunasekera, IS	1
Fang, Y	2
Zhou, XD	1
Zhang, Y	3
Jiang, LF	1
Zhang, JJ	1
Zhou, D	1
Wu, LD	1
Huang, Y	1
Xu, NW	1
Yin, C	1
Er, Z	1
Yu, X	1
Wang, J	2
Wang, X	1
Xie, L	2
Chen, C	1
Zheng, W	1
Xing, F	1
Chen, W	1
Long, C	1
Huang, F	1
Wang, G	1
Xiang, Z	1
Geddes, J	1
McConaghie, G	1
Luo, X	1
Huang, H	2
Tang, X	2
Xu, X	2
Yu, H	1
Hu, Y	1
Ma, H	2
Yao, H	1
Zhang, T	1
Wan, C	1
Zhang, S	2
Xiao, C	2
Yu, W	2
Long, N	2
He, F	1
Cai, P	1
Luo, K	1
Jiang, Y	2
Muse, IO	1
Montilla, E	1
Gruson, KI	1
Berger, J	1
Parot-Schinkel, E	1
Roquilly, A	1
Desebbe, O	1
Garrigue, D	1
Mounet, B	1
Hamard, F	1
Wang, H	2
Long, X	1
Xu, Z	1
Chen, X	2
Li, M	2
He, T	1
Wang, W	2
Liu, L	1
Liu, X	1
Kanthasamy, S	1
Guhan, B	1
Chakravarty, D	1
Parker, MJ	2
Gümüştaş, SA	1
Çelen, ZE	1
Onay, T	1
Abul, MS	1
Çevik, HB	1
Floros, T	2
Chronopoulos, E	2
Skertsou, M	2
Babis, GC	2
Viberg, B	1
Gundtoft, PH	1
Schønnemann, JO	1
Pedersen, L	1
Andersen, LR	1
Titlestad, K	1
Madsen, CF	1
Clemmensen, SB	1
Halekoh, U	1
Lauritsen, J	1
Overgaard, S	1
Suh, YS	1
Nho, JH	1
Seo, J	1
Jang, BW	1
Park, JS	1
Adams, JD	1
Marshall, WA	1
Wadhwa, H	1
Tigchelaar, SS	1
Chen, MJ	1
Koltsov, JCB	1
Bellino, MJ	1
Bishop, JA	1
Gardner, MJ	1
Li, H	1
Liu, D	1
Wang, N	1
Gong, D	1
Wu, Y	1
Li, W	1
Gou, Y	1
Xu, C	1
Wu, M	1
Liu, Y	2
Zhou, P	1
Guan, J	1
Bian, FC	1
Cheng, XK	1
An, YS	1
AlSumadi, M	1
Mahmood, A	1
Whittam, D	1
Kharma, L	1
Ashour, R	1
Banim, R	1
Perskin, CR	1
Littlefield, CP	1
Wang, C	1
Umeh, U	1
Lin, JA	1
Cui, HD	1
Hong, Y	1
Lyu, SJ	1
Witmer, D	1
Solomito, MJ	1
Kumar, M	1
Shearier, E	1
Davis, S	1
Costain, D	1
Elder, G	1
Fraser, B	1
Slagel, B	1
Kelly, A	1
Cheong, Y	1
Fera, L	1
Wei, H	1
Xiao, Q	1
He, J	2
Huang, T	1
Xu, W	1
Xian, S	1
Xia, M	1
Zhang, P	1
Chen, P	1
Liang, Y	1
Lei, J	1
Zhang, B	1
Cong, Y	1
Zhuang, Y	1
Wei, X	1
Fu, Y	1
Wei, W	1
Wang, P	1
Wen, S	1
Han, S	1
Liu, S	1
Baskaran, D	1
Rahman, S	1
Salmasi, Y	1
Froghi, S	1
Berber, O	1
George, M	1
Yu, J	1
Tian, S	1
Shen, Z	1
Peng, A	1
Schiavone, A	1
Bisaccia, M	1
Inkov, I	1
Rinonapoli, G	1
Manni, M	1
Rollo, G	1
Meccariello, L	1
Vicente, CI	1
Ceccarini, P	1
Ruggiero, C	1
Caraffa, A	1
Zhu, Q	1
Yu, C	1
Chen, Y	1
Liu, C	1
Lin, P	1
Peck, J	1
Kepecs, DM	1
Mei, B	1
Safir, OA	1
Backstein, D	1
Gross, AE	1
Kuzyk, PR	1
Jordan, M	1
Aguilera, X	1
González, JC	1
Castillón, P	1
Salomó, M	1
Hernández, JA	1
Ruiz, L	1
Mora, JM	1
Camacho-Carrasco, P	1
Prat-Fabregat, S	1
Bosch, A	1
Rodriguez-Arias, A	1
Martínez-Zapata, MJ	1
Jiang, W	1
Shang, L	1
Kashyap, S	1
Mahajan, S	1
Lal, M	1
Chen, F	1
Jiang, Z	1
Zhu, X	1
Xie, J	1
Hu, Q	1
Chen, G	1
Zhou, Z	1
Pei, F	1
Lee, C	1
Freeman, R	1
Edmondson, M	1
Rogers, BA	1
Drakos, A	1
Raoulis, V	1
Karatzios, K	1
Doxariotis, N	1
Kontogeorgakos, V	1
Malizos, K	1
Varitimidis, SE	1
Tengberg, PT	1
Foss, NB	1
Palm, H	1
Kallemose, T	1
Troelsen, A	1
Gausden, EB	1
Garner, MR	1
Warner, SJ	1
Levack, A	1
Nellestein, AM	1
Tedore, T	1
Flores, E	1
Lorich, DG	1
Coomber, R	1
Porteous, M	1
Hubble, MJW	1
Baruah, RK	1
Borah, PJ	1
Haque, R	1
Zufferey, PJ	1
Miquet, M	1
Quenet, S	1
Martin, P	1
Adam, P	1
Albaladejo, P	1
Mismetti, P	1
Molliex, S	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Comparative Use of Tranexamic Acid Intravenous and Topical Application in the Treatment of Intertrochanteric Fractures With Proximate Femoral Nail[NCT04696224]		90 participants (Anticipated)	Interventional	2020-12-18	Recruiting
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238]	Phase 2	130 participants (Anticipated)	Interventional	2023-04-12	Recruiting
HiFIT Study: Interest of Intravenous Iron and Tranexamic Acid to Reduce Transfusion in Hip Fracture Patients[NCT02972294]	Phase 3	419 participants (Actual)	Interventional	2017-03-31	Terminated (stopped due to 1year inclusion hold due to PV new fact (Monofer hold for risk revaluation) DSMB Interim analysis : 1treatment with important transfusion risk reduction/inclusions issues (COVID)/sites change of practice if study continue=>stop inclusions)
Topical Tranexamic Acid (TXA) in Hip Fractures, A Double-Blind, Randomized Controlled Trial[NCT02993341]	Phase 3	65 participants (Actual)	Interventional	2016-11-30	Completed
The Use of Tranexamic Acid in Chinese Elderly Patients Undergoing Femoral Nailing for Intertrochanteric Fracture: A Randomized Controlled Trial[NCT04290884]	Phase 4	120 participants (Anticipated)	Interventional	2018-05-23	Active, not recruiting
The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures.[NCT04488367]	Early Phase 1	120 participants (Anticipated)	Interventional	2020-07-06	Recruiting
Efficacy of Tranexamic Acid in Femoral Shaft Fractures Osteosynthesis; A Double Blind Randomized Controlled Trial[NCT04803591]	Phase 4	0 participants (Actual)	Interventional	2021-08-01	Withdrawn (stopped due to Not approved by Ethics Commettee)
Does Tranexamic Acid Significantly Reduce Total Blood Loss During Proximal Femoral Nailing for the Intertrochanteric Femoral Fracture in the Elderly?[NCT05359172]		100 participants (Actual)	Observational	2021-04-01	Completed
The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures: A Prospective, Double-Blind, Randomized Controlled Trial[NCT01940536]	Phase 4	0 participants (Actual)	Interventional	2015-12-31	Withdrawn (stopped due to Possible change in study protocol)
Efficacy of Tranexamic Acid on Perioperative Blood Loss During Hip Fracture Surgery.[NCT00327106]	Phase 3	110 participants (Actual)	Interventional	2005-04-30	Completed
Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973]	Phase 3	220 participants (Actual)	Interventional	2018-12-02	Completed
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]	Phase 3	87 participants (Actual)	Interventional	2012-10-31	Completed
The Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin / Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: a Prospective, Randomized, Double-blinded, Multicenter Study[NCT05357079]	Early Phase 1	98 participants (Anticipated)	Interventional	2017-08-25	Recruiting
The Effect of Preoperative Tranexamic Acid on Blood Loss and Transfusion Rates in Intertrochanteric and Subtrochanteric Femur Fractures.[NCT02580227]	Phase 4	100 participants (Anticipated)	Interventional	2015-06-30	Recruiting
Use of Combined Tranexamic Acid and Intravenous Iron for Hip Fracture Surgery in Elderly[NCT02428868]		150 participants (Anticipated)	Interventional	2015-04-30	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

Estimate Blood Loss

Intervention	Participants (Count of Participants)
Tranexamic	21
Placebo	13

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

Number of Participants With a Thromboembolic Event

Intervention	mL (Mean)
Tranexamic	727.6
Placebo	560.1

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

Units of Packed Red Blood Cells Transfused

Intervention	Participants (Count of Participants)
Tranexamic	1
Placebo	0

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

Article	Year
Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials. Injury, 2022, Volume: 53, Issue:2 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Randomized Controlled Tr	2022
Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice. Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:10 Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic	2022
Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis. Orthopaedics & traumatology, surgery & research : OTSR, 2023, Volume: 109, Issue:2 Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemoglobins; Hip Frac	2023
Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Intertrochanteric Fracture. The Journal of bone and joint surgery. American volume, 2022, 07-06, Volume: 104, Issue:13 Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su	2022
The effect of tranexamic acid in open reduction and internal fixation of pelvic and acetabular fracture: A systematic review and meta-analysis. Medicine, 2022, Jul-22, Volume: 101, Issue:29 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; P	2022
Update on the efficacy and safety of intravenous tranexamic acid in hip fracture surgery: a systematic review and meta-analysis. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:5 Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; P	2023
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis. Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2022
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3 Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar	2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3 Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar	2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3 Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar	2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3 Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar	2023
The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. Journal of orthopaedic trauma, 2023, 07-01, Volume: 37, Issue:7 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Network Meta-Analysis; Randomi	2023
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews. The Cochrane database of systematic reviews, 2023, 06-08, Volume: 6 Topics: Aged; Anemia; Emergence Delirium; Erythrocyte Transfusion; Hemorrhage; Hip Fractures; Humans; Iron;	2023
Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. BMC musculoskeletal disorders, 2023, Jul-27, Volume: 24, Issue:1 Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation,	2023
The efficacy and safety of tranexamic acid in the treatment of intertrochanteric fracture: an updated meta-analysis of 11 randomized controlled trials. Journal of thrombosis and thrombolysis, 2020, Volume: 50, Issue:2 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation; Hip Fractures; Human	2020
Postoperative outcomes of tranexamic acid use in geriatric trauma patients treated with proximal femoral intramedullary nails: A systematic review and meta-analysis. Orthopaedics & traumatology, surgery & research : OTSR, 2020, Volume: 106, Issue:1 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture	2020
Efficacy and safety of tranexamic acid for reducing blood loss in elderly patients with intertrochanteric fracture treated with intramedullary fixation surgery: A meta-analysis of randomized controlled trials. Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:1 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture	2020
The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries. The Journal of the American Academy of Orthopaedic Surgeons, 2021, Jun-15, Volume: 29, Issue:12 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic	2021
Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis. Medicine, 2017, Volume: 96, Issue:21 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Orthopedic	2017
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis. Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans	2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis. Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans	2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis. Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans	2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis. Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans	2018
Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. Medicine, 2017, Volume: 96, Issue:52 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; R	2017
Efficacy and Safety of Tranexamic Acid for Blood Salvage in Intertrochanteric Fracture Surgery: A Meta-Analysis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2018, Volume: 24, Issue:8 Topics: Hip Fractures; Humans; Operative Blood Salvage; Postoperative Complications; Thromboembolism; Tranex	2018
Is intravenous tranexamic acid effective and safe during hip fracture surgery? An updated meta-analysis of randomized controlled trials. Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:7 Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Fract	2019
Tranexamic acid can reduce blood loss in patients undergoing intertrochanteric fracture surgery: A meta-analysis. Medicine, 2019, Volume: 98, Issue:11 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hematoma; Hemoglobins; Hip Fractur	2019
Total hip replacement for hip fracture: Surgical techniques and concepts. Injury, 2016, Volume: 47, Issue:10 Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Comorbidity; Elective Surgical Procedures;	2016
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010

Article	Year
Topical administration of tranexamic acid in elderly patients undergoing short femoral nailing for intertrochanteric fracture: A randomised controlled trial. Injury, 2022, Volume: 53, Issue:2 Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Int	2022
Study protocol: haemostatic efficacy and safety of preemptive antifibrinolysis with multidose intravenous tranexamic acid in elderly hip fracture patients: design of a prospective randomised controlled trial. BMJ open, 2021, 12-14, Volume: 11, Issue:12 Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostatics; Hip F	2021
Pre-Emptive Antifibrinolysis: Its Role and Efficacy in Hip Fracture Patients Undergoing Total Hip Arthroplasty. The Journal of arthroplasty, 2022, Volume: 37, Issue:4 Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hip Fractures;	2022
Safety and efficacy of perioperative tranexamic acid infusion in acetabular fracture fixation: A randomized placebo-controlled double-blind prospective study. Injury, 2022, Volume: 53, Issue:10 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hemoglobins; Hip Fractur	2022
A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:11 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture	2022
Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial): a multicentre, 2 × 2 factorial, randomised, double-blind, controlled trial. The Lancet. Haematology, 2023, Volume: 10, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anemia; Blood Transfusion; Double-Blind Method; Female; Hemoglobins;	2023
Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. Orthopaedic surgery, 2019, Volume: 11, Issue:4 Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;	2019
Tranexamic acid safely reduces hidden blood loss in patients undergoing intertrochanteric fracture surgery: a randomized controlled trial. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:2 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Meta-Analysis as Topic; Tranex	2022
Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study). BMJ open, 2021, 01-17, Volume: 11, Issue:1 Topics: Administration, Intravenous; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio	2021
Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial. Journal of orthopaedic surgery and research, 2021, Feb-03, Volume: 16, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage	2021
Infographic: Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial. The bone & joint journal, 2021, Volume: 103-B, Issue:3 Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Bl	2021
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial. The bone & joint journal, 2021, Volume: 103-B, Issue:3 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; F	2021
[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, May-15, Volume: 35, Issue:5 Topics: Administration, Intravenous; Administration, Topical; Blood Loss, Surgical; Bone Nails; Femoral Frac	2021
Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. Canadian journal of surgery. Journal canadien de chirurgie, 2021, 08-10, Volume: 64, Issue:4 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2021
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial. Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures	2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial. Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures	2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial. Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures	2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial. Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures	2017
The effect of tranexamic acid on hidden bleeding in older intertrochanteric fracture patients treated with PFNA. Injury, 2018, Volume: 49, Issue:3 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation, Intramedullary; Hip	2018
Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:5 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement	2019
Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial. Hong Kong medical journal = Xianggang yi xue za zhi, 2019, Volume: 25, Issue:2 Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;	2019
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery. Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial. The bone & joint journal, 2016, Volume: 98-B, Issue:6 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method	2016
Use of tranexamic acid in dynamic hip screw plate fixation for trochanteric fractures. Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:3 Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bone Plates; Bone Scr	2016
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial. British journal of anaesthesia, 2010, Volume: 104, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne	2010

Article	Year
Conversion total hip arthroplasty for early failure following unstable intertrochanteric hip fracture: what can patients expect? Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:12 Topics: Arthroplasty, Replacement, Hip; Bone Screws; Hip Fractures; Humans; Retrospective Studies; Tranexami	2022
Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients. Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:5 Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Frail Elderly;	2022
Clinical Application Effects of Different Preoperative Blood Management Schemes in Older Patients with Delayed Intertrochanteric Fracture Surgery. Clinical interventions in aging, 2022, Volume: 17 Topics: Aged; Blood Loss, Surgical; Erythropoietin; Hip Fractures; Humans; Iron; Retrospective Studies; Tran	2022
Administration of TXA Is Not Associated with Increased Risk of Thromboembolism, Even in Patients Considered High Risk: Commentary on an article by Steven B. Porter, MD, et al.: "Tranexamic Acid Was Not Associated with Increased Complications in High-Risk The Journal of bone and joint surgery. American volume, 2022, 07-06, Volume: 104, Issue:13 Topics: Antifibrinolytic Agents; Hip Fractures; Humans; Thromboembolism; Tranexamic Acid	2022
Does tranexamic acid reliably reduce blood loss in proximal femur fracture surgery? European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:1 Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Co	2023
How does tranexamic acid affect blood transfusion and bleeding amount in pelvis-acetabulum fractures treated with open reduction and internal fixation? Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:9 Topics: Acetabulum; Blood Loss, Surgical; Blood Transfusion; Fracture Fixation, Internal; Fractures, Bone; H	2022
Topical tranexamic acid in intramedullary nailing for the treatment of intertrochanteric fractures in the elderly: A protocol for systematic review and meta-analysis. Medicine, 2023, Feb-10, Volume: 102, Issue:6 Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Sur	2023
Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs. BMC musculoskeletal disorders, 2023, Jul-03, Volume: 24, Issue:1 Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Posto	2023
A prophylactic TXA administration effectively reduces the risk of intraoperative bleeding during open management of pelvic and acetabular fractures. Scientific reports, 2023, 08-02, Volume: 13, Issue:1 Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip F	2023
Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur. Medicine, 2019, Volume: 98, Issue:35 Topics: Acupuncture Points; Acupuncture Therapy; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Los	2019
Does perioperative use of tranexamic acid in hip fracture patients increase the risk of venous thromboembolism and reduce the need for postoperative transfusions? Journal of perioperative practice, 2020, Volume: 30, Issue:12 Topics: Antifibrinolytic Agents; Blood Transfusion; Hip Fractures; Humans; Retrospective Studies; Tranexamic	2020
Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures. Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:2 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Epinephrine; Female; Fractur	2020
[A comparative study of Taylor spatial frame and unilateral external fixator in treatment of tibiofibular open fractures]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Apr-15, Volume: 34, Issue:4 Topics: Blood Loss, Surgical; External Fixators; Fracture Fixation, Internal; Fracture Healing; Fractures, O	2020
Perioperative management of patients with hip fractures and COVID-19: A single institution's early experiences. Journal of clinical anesthesia, 2020, Volume: 67 Topics: Aged; Aged, 80 and over; Anesthesia, Conduction; Antifibrinolytic Agents; COVID-19; Female; Femoral	2020
The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role? Injury, 2021, Volume: 52, Issue:8 Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hum	2021
The efficiency and safety of intravenous tranexamic acid administration in open reduction and internal fixation of pelvic and acetabular fractures. European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:1 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Pelvis; Tranexamic Acid	2022
Is tranexamic acid use in patients with a hip fracture safe? The bone & joint journal, 2021, Volume: 103-B, Issue:3 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark;	2021
Hip Fracture Surgery without Transfusion in Patients with Hemoglobin Less Than 10 g/dL. Clinics in orthopedic surgery, 2021, Volume: 13, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Erythropoietin; Female; Hemoglobins; Hip Fractures	2021
Tranexamic acid does not affect intraoperative blood loss or in-hospital outcomes after acetabular fracture surgery. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:2 Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hospitals; Humans; Middle Aged;	2022
Efficacy of repeated intravenous tranexamic acid in reducing perioperative bleeding of acetabular fractures. Clinical hemorheology and microcirculation, 2021, Volume: 79, Issue:4 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa	2021
Preoperative risk factors for postoperative blood transfusion after hip fracture surgery: establishment of a nomogram. Journal of orthopaedic surgery and research, 2021, Jun-23, Volume: 16, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Anesthesia, General; Arthroplasty; Blood Transfusion; Calibrat	2021
Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients. Journal of perioperative practice, 2022, Volume: 32, Issue:4 Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi	2022
The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery. JBJS reviews, 2021, 07-16, Volume: 9, Issue:7 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Orthopedics; Tranexamic Acid	2021
[Application of tranexamic acid in the treatment of intertrochanteric fracture of femur]. Zhongguo gu shang = China journal of orthopaedics and traumatology, 2021, Jul-25, Volume: 34, Issue:7 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femur; Hip Fractures; Humans; Postoperative Hemorrhag	2021
Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review. Journal of orthopaedic trauma, 2022, Mar-01, Volume: 36, Issue:3 Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa	2022
Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Hip Fracture Undergoing Arthroplasty. The Journal of bone and joint surgery. American volume, 2021, 10-20, Volume: 103, Issue:20 Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Female; Hip	2021
Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA. Medicine, 2021, Aug-27, Volume: 100, Issue:34 Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blo	2021
Tranexamic Acid in Pertrochanteric Femoral Fracture: Is it a Safe Drug or Not? Folia medica, 2018, Mar-01, Volume: 60, Issue:1 Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Transfusion; Female; Fracture Fixation, Intr	2018
The Effect of Preoperative Administration of Intravenous Tranexamic Acid During Revision Hip Arthroplasty: A Retrospective Study. The Journal of bone and joint surgery. American volume, 2018, Sep-05, Volume: 100, Issue:17 Topics: Acetabulum; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood	2018
Effects of topical tranexamic acid during open reduction and internal fixation of acetabular fractures: A retrospective study. Acta orthopaedica et traumatologica turcica, 2019, Volume: 53, Issue:3 Topics: Acetabulum; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio	2019
Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study. BMC musculoskeletal disorders, 2019, Jun-28, Volume: 20, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Tra	2019
The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study. Injury, 2015, Volume: 46, Issue:10 Topics: Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemiarthroplasty; Hip Frac	2015
Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients. BMJ open, 2016, 06-21, Volume: 6, Issue:6 Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi	2016

tranexamic acid and Intertrochanteric Fractures