Page last updated: 2024-11-05

tranexamic acid and Intertrochanteric Fractures

tranexamic acid has been researched along with Intertrochanteric Fractures in 77 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."9.41The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."9.41Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."9.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"Local administration of tranexamic acid is associated with a reduced total blood loss, postoperative hemoglobin decline, and transfusion requirements in patients with intertrochanteric fractures."8.95Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."7.11A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."7.01Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."6.90Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
" There were no complications or adverse effects related to the evaluated interventions."6.90Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."5.41The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."5.41Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."5.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"Local administration of tranexamic acid is associated with a reduced total blood loss, postoperative hemoglobin decline, and transfusion requirements in patients with intertrochanteric fractures."4.95Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"To determine whether locally injected tranexamic acid (TXA) used in the surgical treatment of fragility hip fractures can lower transfusion rates without increasing the risk of complications."4.12Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review. ( Davis, S; Kumar, M; Shearier, E; Solomito, MJ; Witmer, D, 2022)
"The aim of this pre and post interventional study looks at the effects of intravenous administration of tranexamic acid on induction for elderly patients undergoing hemiarthroplasty or intramedullary nail fixation for hip fractures."4.02The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role? ( Chakravarty, D; Guhan, B; Kanthasamy, S; Parker, MJ, 2021)
"The specific method and dose of tranexamic acid (TXA) topically applied for intertrochanteric fractures have not been well established."4.02Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA. ( He, J; Huang, T; Wei, H; Xia, M; Xian, S; Xiao, Q; Xu, W, 2021)
"We investigated the clinical application of auricular point sticking (APS) combined with tranexamic acid in perioperative hemostasis in elderly patients with intertrochanteric fractures of the femur."3.91Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur. ( Er, Z; Yin, C; Zhang, J, 2019)
"Geriatric hip fracture patients are particularly susceptible to blood loss and venous thromboembolism (VTE) during hemiarthroplasty, yet relatively few studies have examined the safety and efficacy of tranexamic acid (TXA) in these patients."3.91Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study. ( Chen, G; Hu, Q; Huang, Q; Pei, F; Xie, J; Zhou, Z, 2019)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."3.11A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Elderly patients with intertrochanteric fractures exhibit post-traumatic hidden blood loss (HBL)."3.01Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial. ( Chen, X; He, T; Li, M; Liu, L; Liu, X; Long, X; Ma, H; Wang, H; Wang, W; Xu, Z, 2021)
"Osteoporotic hip fractures are a major health problem in developed countries."3.01Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis. ( Leverett, GD; Marriott, A, 2023)
"Anemia is one of the most common complications after hip fracture surgery."3.01Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. ( Augustinus, S; Gardenbroek, TJ; Goslings, JC; Mulders, MAM, 2023)
"Tranexamic acid was given intravenously or topically during the perioperative period."3.01Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews. ( Estcourt, LJ; Griffin, XL; Lewis, SR; Pritchard, MW; Stanworth, SJ, 2023)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."3.01Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."2.90Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
" There were no complications or adverse effects related to the evaluated interventions."2.90Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"Eligible patients with trochanteric fractures surgically treated by dynamic hip screw and proximal anti-rotating intramedullary nail between March 2016 and October 2017 were enrolled in the study."2.90Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial. ( Chen, F; Jiang, Z; Li, M; Zhu, X, 2019)
"This meta-analysis provides strong evidence that TXA is a safe and effective agent to reduce perioperative blood loss in hip fracture surgery."2.82Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials. ( Antoniou, G; Masouros, P; Nikolaou, VS, 2022)
" Then, subgroup and meta-regression analyses were conducted to disclose the influence of geographic area, fracture type, administration route, frequency and dosage of TXA, blood transfusion threshold, and follow-up duration on the overall effect."2.82Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice. ( Deng, S; Liang, J; Liu, W, 2022)
"Tranexamic acid (TXA) use has expanded across many surgical specialties."2.72The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries. ( Adams, JD; Marshall, WA, 2021)
"Tranexamic acid (TXA) has been widely used to decrease blood loss and transfusion rates in joint replacement surgery."2.55Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2017)
"Tranexamic acid (TXA) has long been the antifibrinolytic hemostatic drug of choice for orthopedic surgery."1.91Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs. ( Haibier, A; Qin, Q; Ran, J; Ren, Z; Yusufu, A; Zhang, Z; Zhou, Y, 2023)
"The use of tranexamic acid is effective in reduction of blood loss and rates of blood transfusion, without an apparent increase in adverse thromboembolic events."1.72Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients. ( AlSumadi, M; Ashour, R; Banim, R; Kharma, L; Mahmood, A; Whittam, D, 2022)
"Tranexamic acid (TXA) has shown to significantly reduce perioperative blood loss in elective orthopedic joint replacement surgery but is yet not implemented in acute hip fracture surgery for elderly patients who are particularly vulnerable to perioperative blood loss and postoperative anemia."1.72Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients. ( de Jong, L; Kuijper, TM; Roukema, GR; van Rijckevorsel, VAJIM, 2022)
"Tranexamic acid was used less often in the CTHA group (p < 0."1.72Conversion total hip arthroplasty for early failure following unstable intertrochanteric hip fracture: what can patients expect? ( Egol, KA; Penev, A; Schultz, BJ; Schwarzkopf, R; Sicat, C, 2022)
"Tranexamic acid (TXA) is a drug used to control hemorrhage by preventing the breakdown of fibrin."1.62The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery. ( Egol, KA; Littlefield, CP; Perskin, CR; Umeh, U; Wang, C, 2021)
" Thus, we conclude that it is safe to use TXA in this patient group."1.62Is tranexamic acid use in patients with a hip fracture safe? ( Andersen, LR; Clemmensen, SB; Gundtoft, PH; Halekoh, U; Lauritsen, J; Madsen, CF; Overgaard, S; Pedersen, L; Schønnemann, JO; Titlestad, K; Viberg, B, 2021)
" Our study indicates that the local administration of TXA/DEP is safe and more effective than the administration of TXA alone in treating trochanteric femoral fractures."1.56Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures. ( Hu, Y; Xie, L; Xu, X; Yu, H, 2020)
"Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general trauma patients as well as patients undergoing elective orthopaedic surgery."1.43Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients. ( Flores, E; Garner, MR; Gausden, EB; Levack, A; Lorich, DG; Nellestein, AM; Tedore, T; Warner, SJ, 2016)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective lower limb arthroplasty surgery."1.42The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study. ( Edmondson, M; Freeman, R; Lee, C; Rogers, BA, 2015)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's23 (29.87)24.3611
2020's54 (70.13)2.80

Authors

AuthorsStudies
Schultz, BJ1
Sicat, C1
Penev, A1
Schwarzkopf, R1
Egol, KA2
Masouros, P3
Antoniou, G1
Nikolaou, VS3
Liu, W1
Deng, S1
Liang, J1
Yee, DK1
Wong, JSH1
Fang, E1
Wong, TM1
Fang, C1
Leung, F1
Liu, J2
Lei, Y2
Liao, J2
Liang, X2
Hu, N2
Huang, W2
van Rijckevorsel, VAJIM1
Roukema, GR1
Kuijper, TM1
de Jong, L1
Cui, Y1
Lu, Y1
Huang, Q2
Zhang, C1
Sun, L1
Ren, C1
Wang, Q1
Ma, T1
Li, Z1
Zhang, K2
Wang, Z2
Xue, H1
Leverett, GD1
Marriott, A1
Porter, SB2
Spaulding, AC2
Duncan, CM2
Wilke, BK2
Pagnano, MW2
Abdel, MP2
Cornell, C1
Fenwick, A1
Antonovska, I1
Pfann, M1
Mayr, J1
Wiedl, A1
Nuber, S1
Förch, S1
Mayr, E1
Kim, CH1
Hwang, J1
Lee, SJ1
Yoon, PW1
Yoon, KS1
Sen, RK1
Attar, MU1
Saini, G1
Tripathy, SK1
Tekin, SB1
Demir, IH1
Bozgeyik, B1
Mert, A1
Miangul, S1
Oluwaremi, T1
El Haddad, J1
Adra, M1
Pinnawala, N1
Nakanishi, H1
Matar, RH1
Than, CA1
Stewart, TM1
Ekinci, M1
Ok, M1
Ersin, M1
Günen, E1
Kocazeybek, E1
Sırma, SÖ1
Yılmaz, M1
Agius, C3
Cole, E3
Mifsud, MG3
Vasireddy, A3
Augustinus, S2
Mulders, MAM2
Gardenbroek, TJ2
Goslings, JC2
Zhang, J3
Fan, X2
Zheng, Y2
Wu, J2
Yuan, X2
Bloom, DA1
Lin, CC1
Manzi, JE1
Mojica, ES1
Telgheder, ZL1
Chapman, CB1
Konda, SR1
Lewis, SR1
Pritchard, MW1
Estcourt, LJ1
Stanworth, SJ1
Griffin, XL1
Yusufu, A1
Haibier, A1
Ren, Z1
Qin, Q1
Zhang, Z1
Zhou, Y1
Ran, J1
Lasocki, S2
Capdevila, X1
Vielle, B2
Bijok, B1
Lahlou-Casulli, M2
Collange, V2
Grillot, N1
Danguy des Deserts, M2
Duchalais, A2
Delannoy, B1
Drugeon, B2
Bouzat, P2
David, JS2
Rony, L1
Loupec, T2
Léger, M2
Rineau, E2
Kenmegne, GR1
Zou, C1
Lin, Y1
Yin, Y1
Huang, S1
Banneyake, EL1
Gunasekera, IS1
Fang, Y2
Zhou, XD1
Zhang, Y3
Jiang, LF1
Zhang, JJ1
Zhou, D1
Wu, LD1
Huang, Y1
Xu, NW1
Yin, C1
Er, Z1
Yu, X1
Wang, J2
Wang, X1
Xie, L2
Chen, C1
Zheng, W1
Xing, F1
Chen, W1
Long, C1
Huang, F1
Wang, G1
Xiang, Z1
Geddes, J1
McConaghie, G1
Luo, X1
Huang, H2
Tang, X2
Xu, X2
Yu, H1
Hu, Y1
Ma, H2
Yao, H1
Zhang, T1
Wan, C1
Zhang, S2
Xiao, C2
Yu, W2
Long, N2
He, F1
Cai, P1
Luo, K1
Jiang, Y2
Muse, IO1
Montilla, E1
Gruson, KI1
Berger, J1
Parot-Schinkel, E1
Roquilly, A1
Desebbe, O1
Garrigue, D1
Mounet, B1
Hamard, F1
Wang, H2
Long, X1
Xu, Z1
Chen, X2
Li, M2
He, T1
Wang, W2
Liu, L1
Liu, X1
Kanthasamy, S1
Guhan, B1
Chakravarty, D1
Parker, MJ2
Gümüştaş, SA1
Çelen, ZE1
Onay, T1
Abul, MS1
Çevik, HB1
Floros, T2
Chronopoulos, E2
Skertsou, M2
Babis, GC2
Viberg, B1
Gundtoft, PH1
Schønnemann, JO1
Pedersen, L1
Andersen, LR1
Titlestad, K1
Madsen, CF1
Clemmensen, SB1
Halekoh, U1
Lauritsen, J1
Overgaard, S1
Suh, YS1
Nho, JH1
Seo, J1
Jang, BW1
Park, JS1
Adams, JD1
Marshall, WA1
Wadhwa, H1
Tigchelaar, SS1
Chen, MJ1
Koltsov, JCB1
Bellino, MJ1
Bishop, JA1
Gardner, MJ1
Li, H1
Liu, D1
Wang, N1
Gong, D1
Wu, Y1
Li, W1
Gou, Y1
Xu, C1
Wu, M1
Liu, Y2
Zhou, P1
Guan, J1
Bian, FC1
Cheng, XK1
An, YS1
AlSumadi, M1
Mahmood, A1
Whittam, D1
Kharma, L1
Ashour, R1
Banim, R1
Perskin, CR1
Littlefield, CP1
Wang, C1
Umeh, U1
Lin, JA1
Cui, HD1
Hong, Y1
Lyu, SJ1
Witmer, D1
Solomito, MJ1
Kumar, M1
Shearier, E1
Davis, S1
Costain, D1
Elder, G1
Fraser, B1
Slagel, B1
Kelly, A1
Cheong, Y1
Fera, L1
Wei, H1
Xiao, Q1
He, J2
Huang, T1
Xu, W1
Xian, S1
Xia, M1
Zhang, P1
Chen, P1
Liang, Y1
Lei, J1
Zhang, B1
Cong, Y1
Zhuang, Y1
Wei, X1
Fu, Y1
Wei, W1
Wang, P1
Wen, S1
Han, S1
Liu, S1
Baskaran, D1
Rahman, S1
Salmasi, Y1
Froghi, S1
Berber, O1
George, M1
Yu, J1
Tian, S1
Shen, Z1
Peng, A1
Schiavone, A1
Bisaccia, M1
Inkov, I1
Rinonapoli, G1
Manni, M1
Rollo, G1
Meccariello, L1
Vicente, CI1
Ceccarini, P1
Ruggiero, C1
Caraffa, A1
Zhu, Q1
Yu, C1
Chen, Y1
Liu, C1
Lin, P1
Peck, J1
Kepecs, DM1
Mei, B1
Safir, OA1
Backstein, D1
Gross, AE1
Kuzyk, PR1
Jordan, M1
Aguilera, X1
González, JC1
Castillón, P1
Salomó, M1
Hernández, JA1
Ruiz, L1
Mora, JM1
Camacho-Carrasco, P1
Prat-Fabregat, S1
Bosch, A1
Rodriguez-Arias, A1
Martínez-Zapata, MJ1
Jiang, W1
Shang, L1
Kashyap, S1
Mahajan, S1
Lal, M1
Chen, F1
Jiang, Z1
Zhu, X1
Xie, J1
Hu, Q1
Chen, G1
Zhou, Z1
Pei, F1
Lee, C1
Freeman, R1
Edmondson, M1
Rogers, BA1
Drakos, A1
Raoulis, V1
Karatzios, K1
Doxariotis, N1
Kontogeorgakos, V1
Malizos, K1
Varitimidis, SE1
Tengberg, PT1
Foss, NB1
Palm, H1
Kallemose, T1
Troelsen, A1
Gausden, EB1
Garner, MR1
Warner, SJ1
Levack, A1
Nellestein, AM1
Tedore, T1
Flores, E1
Lorich, DG1
Coomber, R1
Porteous, M1
Hubble, MJW1
Baruah, RK1
Borah, PJ1
Haque, R1
Zufferey, PJ1
Miquet, M1
Quenet, S1
Martin, P1
Adam, P1
Albaladejo, P1
Mismetti, P1
Molliex, S1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Use of Tranexamic Acid Intravenous and Topical Application in the Treatment of Intertrochanteric Fractures With Proximate Femoral Nail[NCT04696224]90 participants (Anticipated)Interventional2020-12-18Recruiting
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238]Phase 2130 participants (Anticipated)Interventional2023-04-12Recruiting
HiFIT Study: Interest of Intravenous Iron and Tranexamic Acid to Reduce Transfusion in Hip Fracture Patients[NCT02972294]Phase 3419 participants (Actual)Interventional2017-03-31Terminated (stopped due to 1year inclusion hold due to PV new fact (Monofer hold for risk revaluation) DSMB Interim analysis : 1treatment with important transfusion risk reduction/inclusions issues (COVID)/sites change of practice if study continue=>stop inclusions)
Topical Tranexamic Acid (TXA) in Hip Fractures, A Double-Blind, Randomized Controlled Trial[NCT02993341]Phase 365 participants (Actual)Interventional2016-11-30Completed
The Use of Tranexamic Acid in Chinese Elderly Patients Undergoing Femoral Nailing for Intertrochanteric Fracture: A Randomized Controlled Trial[NCT04290884]Phase 4120 participants (Anticipated)Interventional2018-05-23Active, not recruiting
The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures.[NCT04488367]Early Phase 1120 participants (Anticipated)Interventional2020-07-06Recruiting
Efficacy of Tranexamic Acid in Femoral Shaft Fractures Osteosynthesis; A Double Blind Randomized Controlled Trial[NCT04803591]Phase 40 participants (Actual)Interventional2021-08-01Withdrawn (stopped due to Not approved by Ethics Commettee)
Does Tranexamic Acid Significantly Reduce Total Blood Loss During Proximal Femoral Nailing for the Intertrochanteric Femoral Fracture in the Elderly?[NCT05359172]100 participants (Actual)Observational2021-04-01Completed
The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures: A Prospective, Double-Blind, Randomized Controlled Trial[NCT01940536]Phase 40 participants (Actual)Interventional2015-12-31Withdrawn (stopped due to Possible change in study protocol)
Efficacy of Tranexamic Acid on Perioperative Blood Loss During Hip Fracture Surgery.[NCT00327106]Phase 3110 participants (Actual)Interventional2005-04-30Completed
Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973]Phase 3220 participants (Actual)Interventional2018-12-02Completed
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
The Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin / Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: a Prospective, Randomized, Double-blinded, Multicenter Study[NCT05357079]Early Phase 198 participants (Anticipated)Interventional2017-08-25Recruiting
The Effect of Preoperative Tranexamic Acid on Blood Loss and Transfusion Rates in Intertrochanteric and Subtrochanteric Femur Fractures.[NCT02580227]Phase 4100 participants (Anticipated)Interventional2015-06-30Recruiting
Use of Combined Tranexamic Acid and Intravenous Iron for Hip Fracture Surgery in Elderly[NCT02428868]150 participants (Anticipated)Interventional2015-04-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Reviews

23 reviews available for tranexamic acid and Intertrochanteric Fractures

ArticleYear
Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials.
    Injury, 2022, Volume: 53, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Randomized Controlled Tr

2022
Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice.
    Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2022
Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis.
    Orthopaedics & traumatology, surgery & research : OTSR, 2023, Volume: 109, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemoglobins; Hip Frac

2023
Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Intertrochanteric Fracture.
    The Journal of bone and joint surgery. American volume, 2022, 07-06, Volume: 104, Issue:13

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2022
The effect of tranexamic acid in open reduction and internal fixation of pelvic and acetabular fracture: A systematic review and meta-analysis.
    Medicine, 2022, Jul-22, Volume: 101, Issue:29

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; P

2022
Update on the efficacy and safety of intravenous tranexamic acid in hip fracture surgery: a systematic review and meta-analysis.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; P

2023
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis.
    Journal of orthopaedic trauma, 2023, 07-01, Volume: 37, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Network Meta-Analysis; Randomi

2023
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews.
    The Cochrane database of systematic reviews, 2023, 06-08, Volume: 6

    Topics: Aged; Anemia; Emergence Delirium; Erythrocyte Transfusion; Hemorrhage; Hip Fractures; Humans; Iron;

2023
Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2023, Jul-27, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation,

2023
The efficacy and safety of tranexamic acid in the treatment of intertrochanteric fracture: an updated meta-analysis of 11 randomized controlled trials.
    Journal of thrombosis and thrombolysis, 2020, Volume: 50, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation; Hip Fractures; Human

2020
Postoperative outcomes of tranexamic acid use in geriatric trauma patients treated with proximal femoral intramedullary nails: A systematic review and meta-analysis.
    Orthopaedics & traumatology, surgery & research : OTSR, 2020, Volume: 106, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2020
Efficacy and safety of tranexamic acid for reducing blood loss in elderly patients with intertrochanteric fracture treated with intramedullary fixation surgery: A meta-analysis of randomized controlled trials.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2020
The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2021, Jun-15, Volume: 29, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2021
Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:21

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Orthopedic

2017
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:52

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; R

2017
Efficacy and Safety of Tranexamic Acid for Blood Salvage in Intertrochanteric Fracture Surgery: A Meta-Analysis.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2018, Volume: 24, Issue:8

    Topics: Hip Fractures; Humans; Operative Blood Salvage; Postoperative Complications; Thromboembolism; Tranex

2018
Is intravenous tranexamic acid effective and safe during hip fracture surgery? An updated meta-analysis of randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:7

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Fract

2019
Tranexamic acid can reduce blood loss in patients undergoing intertrochanteric fracture surgery: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hematoma; Hemoglobins; Hip Fractur

2019
Total hip replacement for hip fracture: Surgical techniques and concepts.
    Injury, 2016, Volume: 47, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Comorbidity; Elective Surgical Procedures;

2016
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010

Trials

22 trials available for tranexamic acid and Intertrochanteric Fractures

ArticleYear
Topical administration of tranexamic acid in elderly patients undergoing short femoral nailing for intertrochanteric fracture: A randomised controlled trial.
    Injury, 2022, Volume: 53, Issue:2

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Int

2022
Study protocol: haemostatic efficacy and safety of preemptive antifibrinolysis with multidose intravenous tranexamic acid in elderly hip fracture patients: design of a prospective randomised controlled trial.
    BMJ open, 2021, 12-14, Volume: 11, Issue:12

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostatics; Hip F

2021
Pre-Emptive Antifibrinolysis: Its Role and Efficacy in Hip Fracture Patients Undergoing Total Hip Arthroplasty.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hip Fractures;

2022
Safety and efficacy of perioperative tranexamic acid infusion in acetabular fracture fixation: A randomized placebo-controlled double-blind prospective study.
    Injury, 2022, Volume: 53, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hemoglobins; Hip Fractur

2022
A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2022
Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial): a multicentre, 2 × 2 factorial, randomised, double-blind, controlled trial.
    The Lancet. Haematology, 2023, Volume: 10, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Blood Transfusion; Double-Blind Method; Female; Hemoglobins;

2023
Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial.
    Orthopaedic surgery, 2019, Volume: 11, Issue:4

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;

2019
Tranexamic acid safely reduces hidden blood loss in patients undergoing intertrochanteric fracture surgery: a randomized controlled trial.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Meta-Analysis as Topic; Tranex

2022
Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study).
    BMJ open, 2021, 01-17, Volume: 11, Issue:1

    Topics: Administration, Intravenous; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio

2021
Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial.
    Journal of orthopaedic surgery and research, 2021, Feb-03, Volume: 16, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage

2021
Infographic: Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial.
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Bl

2021
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial.
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; F

2021
[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, May-15, Volume: 35, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Blood Loss, Surgical; Bone Nails; Femoral Frac

2021
Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study.
    Canadian journal of surgery. Journal canadien de chirurgie, 2021, 08-10, Volume: 64, Issue:4

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2021
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial.
    Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures

2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial.
    Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures

2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial.
    Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures

2017
Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial.
    Journal of orthopaedic surgery and research, 2017, Aug-15, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Female; Fracture Fixation, Internal; Hip Fractures

2017
The effect of tranexamic acid on hidden bleeding in older intertrochanteric fracture patients treated with PFNA.
    Injury, 2018, Volume: 49, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation, Intramedullary; Hip

2018
Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study).
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2019
Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2019, Volume: 25, Issue:2

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;

2019
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Use of tranexamic acid in dynamic hip screw plate fixation for trochanteric fractures.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:3

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bone Plates; Bone Scr

2016
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010

Other Studies

33 other studies available for tranexamic acid and Intertrochanteric Fractures

ArticleYear
Conversion total hip arthroplasty for early failure following unstable intertrochanteric hip fracture: what can patients expect?
    Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:12

    Topics: Arthroplasty, Replacement, Hip; Bone Screws; Hip Fractures; Humans; Retrospective Studies; Tranexami

2022
Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients.
    Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Frail Elderly;

2022
Clinical Application Effects of Different Preoperative Blood Management Schemes in Older Patients with Delayed Intertrochanteric Fracture Surgery.
    Clinical interventions in aging, 2022, Volume: 17

    Topics: Aged; Blood Loss, Surgical; Erythropoietin; Hip Fractures; Humans; Iron; Retrospective Studies; Tran

2022
Administration of TXA Is Not Associated with Increased Risk of Thromboembolism, Even in Patients Considered High Risk: Commentary on an article by Steven B. Porter, MD, et al.: "Tranexamic Acid Was Not Associated with Increased Complications in High-Risk
    The Journal of bone and joint surgery. American volume, 2022, 07-06, Volume: 104, Issue:13

    Topics: Antifibrinolytic Agents; Hip Fractures; Humans; Thromboembolism; Tranexamic Acid

2022
Does tranexamic acid reliably reduce blood loss in proximal femur fracture surgery?
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:1

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Co

2023
How does tranexamic acid affect blood transfusion and bleeding amount in pelvis-acetabulum fractures treated with open reduction and internal fixation?
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:9

    Topics: Acetabulum; Blood Loss, Surgical; Blood Transfusion; Fracture Fixation, Internal; Fractures, Bone; H

2022
Topical tranexamic acid in intramedullary nailing for the treatment of intertrochanteric fractures in the elderly: A protocol for systematic review and meta-analysis.
    Medicine, 2023, Feb-10, Volume: 102, Issue:6

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Sur

2023
Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs.
    BMC musculoskeletal disorders, 2023, Jul-03, Volume: 24, Issue:1

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Posto

2023
A prophylactic TXA administration effectively reduces the risk of intraoperative bleeding during open management of pelvic and acetabular fractures.
    Scientific reports, 2023, 08-02, Volume: 13, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip F

2023
Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur.
    Medicine, 2019, Volume: 98, Issue:35

    Topics: Acupuncture Points; Acupuncture Therapy; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Los

2019
Does perioperative use of tranexamic acid in hip fracture patients increase the risk of venous thromboembolism and reduce the need for postoperative transfusions?
    Journal of perioperative practice, 2020, Volume: 30, Issue:12

    Topics: Antifibrinolytic Agents; Blood Transfusion; Hip Fractures; Humans; Retrospective Studies; Tranexamic

2020
Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Epinephrine; Female; Fractur

2020
[A comparative study of Taylor spatial frame and unilateral external fixator in treatment of tibiofibular open fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Apr-15, Volume: 34, Issue:4

    Topics: Blood Loss, Surgical; External Fixators; Fracture Fixation, Internal; Fracture Healing; Fractures, O

2020
Perioperative management of patients with hip fractures and COVID-19: A single institution's early experiences.
    Journal of clinical anesthesia, 2020, Volume: 67

    Topics: Aged; Aged, 80 and over; Anesthesia, Conduction; Antifibrinolytic Agents; COVID-19; Female; Femoral

2020
The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role?
    Injury, 2021, Volume: 52, Issue:8

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hum

2021
The efficiency and safety of intravenous tranexamic acid administration in open reduction and internal fixation of pelvic and acetabular fractures.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Pelvis; Tranexamic Acid

2022
Is tranexamic acid use in patients with a hip fracture safe?
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark;

2021
Hip Fracture Surgery without Transfusion in Patients with Hemoglobin Less Than 10 g/dL.
    Clinics in orthopedic surgery, 2021, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Erythropoietin; Female; Hemoglobins; Hip Fractures

2021
Tranexamic acid does not affect intraoperative blood loss or in-hospital outcomes after acetabular fracture surgery.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hospitals; Humans; Middle Aged;

2022
Efficacy of repeated intravenous tranexamic acid in reducing perioperative bleeding of acetabular fractures.
    Clinical hemorheology and microcirculation, 2021, Volume: 79, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa

2021
Preoperative risk factors for postoperative blood transfusion after hip fracture surgery: establishment of a nomogram.
    Journal of orthopaedic surgery and research, 2021, Jun-23, Volume: 16, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Anesthesia, General; Arthroplasty; Blood Transfusion; Calibrat

2021
Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients.
    Journal of perioperative practice, 2022, Volume: 32, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2022
The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery.
    JBJS reviews, 2021, 07-16, Volume: 9, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Orthopedics; Tranexamic Acid

2021
[Application of tranexamic acid in the treatment of intertrochanteric fracture of femur].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2021, Jul-25, Volume: 34, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femur; Hip Fractures; Humans; Postoperative Hemorrhag

2021
Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review.
    Journal of orthopaedic trauma, 2022, Mar-01, Volume: 36, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa

2022
Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Hip Fracture Undergoing Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2021, 10-20, Volume: 103, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Female; Hip

2021
Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA.
    Medicine, 2021, Aug-27, Volume: 100, Issue:34

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blo

2021
Tranexamic Acid in Pertrochanteric Femoral Fracture: Is it a Safe Drug or Not?
    Folia medica, 2018, Mar-01, Volume: 60, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Transfusion; Female; Fracture Fixation, Intr

2018
The Effect of Preoperative Administration of Intravenous Tranexamic Acid During Revision Hip Arthroplasty: A Retrospective Study.
    The Journal of bone and joint surgery. American volume, 2018, Sep-05, Volume: 100, Issue:17

    Topics: Acetabulum; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood

2018
Effects of topical tranexamic acid during open reduction and internal fixation of acetabular fractures: A retrospective study.
    Acta orthopaedica et traumatologica turcica, 2019, Volume: 53, Issue:3

    Topics: Acetabulum; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio

2019
Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study.
    BMC musculoskeletal disorders, 2019, Jun-28, Volume: 20, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Tra

2019
The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study.
    Injury, 2015, Volume: 46, Issue:10

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemiarthroplasty; Hip Frac

2015
Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients.
    BMJ open, 2016, 06-21, Volume: 6, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2016