Page last updated: 2024-11-05

tranexamic acid and Infection, Postoperative Wound

tranexamic acid has been researched along with Infection, Postoperative Wound in 10 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"A randomized double-blind trial has shown that, in 160 women with breast cancer undergoing lumpectomy or mastectomy with axillary clearance, perioperative and postoperative administration of tranexamic acid 1 g three times daily resulted in a significant reduction in the mean postoperative drainage volume compared with patients given placebo (283 versus 432 ml, P < 0."9.07Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer. ( Haberthuer, F; Harder, F; Kreuter, U; Laffer, U; Oertli, D, 1994)
"The combined use of intraarticular topical TXA with rivaroxaban in patients undergoing TKA is a safe and effective method to reduce blood loss, the need for transfusion, and wound complications without elevating the risk of DVT."5.48Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis. ( Kang, MW; Kim, JI; Kim, YT; Lee, JK; Lee, YM, 2018)
"A randomized double-blind trial has shown that, in 160 women with breast cancer undergoing lumpectomy or mastectomy with axillary clearance, perioperative and postoperative administration of tranexamic acid 1 g three times daily resulted in a significant reduction in the mean postoperative drainage volume compared with patients given placebo (283 versus 432 ml, P < 0."5.07Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer. ( Haberthuer, F; Harder, F; Kreuter, U; Laffer, U; Oertli, D, 1994)
"Tranexamic acid (TXA) has been widely utilized to reduce blood loss and allogeneic transfusions in patients who undergo lower limb arthroplasty."4.40Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis. ( Choe, H; Imanishi, K; Inaba, Y; Kamono, E; Kobayashi, N; Kumagai, K; Takagawa, S; Yukizawa, Y, 2023)
"Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty."2.53Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2016)
"Tranexamic acid is an effective treatment to reduce blood loss."1.91The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan. ( Chen, JW; Hou, SM; Hsu, HW; Hsu, LI; Wei, ST, 2023)
"The combined use of intraarticular topical TXA with rivaroxaban in patients undergoing TKA is a safe and effective method to reduce blood loss, the need for transfusion, and wound complications without elevating the risk of DVT."1.48Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis. ( Kang, MW; Kim, JI; Kim, YT; Lee, JK; Lee, YM, 2018)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Hsu, LI3
Hsu, HW3
Chen, JW3
Wei, ST3
Hou, SM3
Imanishi, K1
Kobayashi, N1
Kamono, E1
Yukizawa, Y1
Takagawa, S1
Choe, H1
Kumagai, K1
Inaba, Y1
Jacobson, RA1
Wienholts, K1
Williamson, AJ1
Gaines, S1
Hyoju, S1
van Goor, H1
Zaborin, A1
Shogan, BD1
Zaborina, O1
Alverdy, JC1
Kim, YT1
Kang, MW1
Lee, JK1
Lee, YM1
Kim, JI1
Peck, J1
Kepecs, DM1
Mei, B1
Safir, OA1
Backstein, D1
Gross, AE1
Kuzyk, PR1
Maniar, RN1
Pradhan, P1
Bhatnagar, N1
Maniar, A1
Bidwai, R1
Bindal, P1
Rasouli, MR1
Gomes, LS1
Parsley, B1
Barsoum, W1
Bezwada, H1
Cashman, J1
Garcia, J1
Hamilton, W1
Hume, E1
Malhotra, R1
Memtsoudis, S1
Ong, A1
Orozco, F1
Padgett, D1
Reina, R1
Teloken, M1
Thienpont, E1
Waters, JH1
Wang, C1
Xu, GJ1
Han, Z1
Ma, JX1
Ma, XL1
Jiang, X1
Wang, Y1
Zhang, P1
Liang, Y1
Chen, P1
Fang, Y1
He, J1
Wang, J1
Oertli, D1
Laffer, U1
Haberthuer, F1
Kreuter, U1
Harder, F1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomized Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty[NCT03359525]Phase 4114 participants (Anticipated)Interventional2017-07-01Recruiting
Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma[NCT00307606]Phase 440 participants (Anticipated)Interventional2005-12-31Recruiting
Minimization of Bleeding Complications Through Utilization of Perioperative Tranexamic Acid in Breast Surgery: A Randomized Double-blinded Placebo-controlled Trial[NCT02615366]Phase 4800 participants (Anticipated)Interventional2016-02-29Not yet recruiting
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527]Phase 4100 participants (Anticipated)Interventional2019-10-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for tranexamic acid and Infection, Postoperative Wound

ArticleYear
Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement,

2023
Topical application of tranexamic acid in primary total hip arthroplasty: a systemic review and meta-analysis.
    International journal of surgery (London, England), 2015, Volume: 15

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion;

2015
Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:50

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016

Trials

3 trials available for tranexamic acid and Infection, Postoperative Wound

ArticleYear
Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement,

2023
Role of Suction Drain after Knee Arthroplasty in the Tranexamic Acid Era: A Randomized Controlled Study.
    Clinics in orthopedic surgery, 2019, Volume: 11, Issue:1

    Topics: Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Edema; Female; H

2019
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994

Other Studies

5 other studies available for tranexamic acid and Infection, Postoperative Wound

ArticleYear
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
    American journal of physiology. Gastrointestinal and liver physiology, 2020, 01-01, Volume: 318, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antifibrinolytic Agents; Collagen Type I; Collagen Type IV; Colon; D

2020
Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis.
    BMC musculoskeletal disorders, 2018, Jul-18, Volume: 19, Issue:1

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2018
The Effect of Preoperative Administration of Intravenous Tranexamic Acid During Revision Hip Arthroplasty: A Retrospective Study.
    The Journal of bone and joint surgery. American volume, 2018, Sep-05, Volume: 100, Issue:17

    Topics: Acetabulum; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood

2018
Blood conservation.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32 Suppl 1

    Topics: Anesthesia; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement; Blood Loss, S

2014