tranexamic acid has been researched along with Hypermobility, Joint in 4 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, there was significantly lower postoperative blood loss with TXA (29." | 2.94 | Tranexamic acid for the Latarjet procedure: a randomized controlled trial. ( Hurley, ET; Lim Fat, D; Mullett, H; Pauzenberger, L, 2020) |
| "Intraoperative and postoperative blood loss were compared between the two groups." | 2.78 | Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial. ( Bi, Y; Chen, Y; Fan, R; Guo, M; Hua, Z; Liu, J; Piao, M; Ren, W; Wang, Q; Xiang, L; Yu, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hurley, ET | 1 |
| Lim Fat, D | 1 |
| Pauzenberger, L | 1 |
| Mullett, H | 1 |
| Yuan, X | 1 |
| Wang, J | 1 |
| Wang, Q | 2 |
| Zhang, X | 1 |
| Liu, J | 1 |
| Fan, R | 1 |
| Chen, Y | 1 |
| Yu, H | 1 |
| Bi, Y | 1 |
| Hua, Z | 1 |
| Piao, M | 1 |
| Guo, M | 1 |
| Ren, W | 1 |
| Xiang, L | 1 |
| Endres, S | 1 |
| Heinz, M | 1 |
| Wilke, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery[NCT01728636] | Phase 2 | 61 participants (Actual) | Interventional | 2013-01-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total additional blood products (fresh frozen plasma, cryoprecipitate, and platelets) transfused in the perioperative period measured in units. (NCT01728636)
Timeframe: 24 hours after skin incision
| Intervention | Units (Mean) |
|---|---|
| Tranexamic Acid | 1 |
| Placebo | 2 |
Estimated Intraoperative blood loss in milliliters (mLs) (NCT01728636)
Timeframe: Incision to skin closure (approximately 10 hours)
| Intervention | Milliliters (Mean) |
|---|---|
| Tranexamic Acid | 1550 |
| Placebo | 1600 |
Number of participants who experienced arterial or venous thromboembolism, neurologic complications (including stroke, seizure,and delirium), infections, and pulmonary renal or cardiac adverse outcomes (demand ischemia, myocardial infarction or new arrhythmia) before another operative procedure or hospital discharge. (NCT01728636)
Timeframe: Time of surgery to date of discharge from hospital (average 7 days)
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 9 |
| Placebo | 9 |
Total operating room time from incision to closure of incision in minutes. (NCT01728636)
Timeframe: Minutes
| Intervention | Minutes (Median) |
|---|---|
| Tranexamic Acid | 602 |
| Placebo | 576 |
Total red blood cells transfused in the intraoperative period in (mL). Total RBC equal packed red blood cells and cell saver infusion. (NCT01728636)
Timeframe: Intraoperative period (approximately 12 hours)
| Intervention | milliliters (Median) |
|---|---|
| Tranexamic Acid | 1140 |
| Placebo | 1460 |
Total milligrams of intravenous tranexamic acid administered during the surgical procedure. (NCT01728636)
Timeframe: Intraoperative period
| Intervention | milligrams (Median) |
|---|---|
| Tranexamic Acid | 1408 |
| Placebo | 0 |
3 trials available for tranexamic acid and Hypermobility, Joint
| Article | Year |
|---|---|
Tranexamic acid for the Latarjet procedure: a randomized controlled trial.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antifibrinolytic Agents; Blood Loss, Surgica | 2020 |
Synergistic effects of intravenous and intra-articular tranexamic acid on reducing hemoglobin loss in revision total knee arthroplasty: a prospective, randomized, controlled study.
Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus | 2018 |
Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial.
Topics: Aged; Antifibrinolytic Agents; Blood Coagulation Tests; Decompression, Surgical; Female; Humans; Int | 2013 |
1 other study available for tranexamic acid and Hypermobility, Joint
| Article | Year |
|---|---|
Efficacy of tranexamic acid in reducing blood loss in posterior lumbar spine surgery for degenerative spinal stenosis with instability: a retrospective case control study.
Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Decompression, Surgical; Dose-Response Relation | 2011 |