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tranexamic acid and Hemorrhagic Disorders

tranexamic acid has been researched along with Hemorrhagic Disorders in 20 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Hemorrhagic Disorders: Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a structural flaw in the blood vessels (HEMOSTATIC DISORDERS).

Research Excerpts

ExcerptRelevanceReference
" To control the hemorrhagic diathesis, we commenced combination therapy for DIC with danaparoid (1,250 Ux2/day, intravenously (IV)) and tranexamic acid (0."7.73Kasabach-Merritt syndrome associated with giant liver hemangioma: the effect of combined therapy with danaparoid sodium and tranexamic acid. ( Asakura, H; Matsui, O; Nakao, S; Omote, M; Ontachi, Y; Yoshida, T, 2005)
"Tranexamic acid was administered for menorrhagia and resumed later for labor and continued into the postpartum period since antifibrinolytics have been the mainstay in the management of PAI-1 deficiency."5.56The utility of thromboelastography and tranexamic acid in plasminogen activator inhibitor deficiency during pregnancy: a rare case report. ( Hammer, RD; Laziuk, K; Prabhakaran, N, 2020)
" Systematic review and meta-analysis to determine the bleeding rates associated with tranexamic acid, desmopressin, platelet transfusion, plasma transfusion and recombinant activated factor VII, for patients with unclassified bleeding disorders undergoing surgery, childbirth or with menorrhagia."5.12Management of surgery, menorrhagia and child-birth for patients with unclassified bleeding disorders: a systematic review of cohort studies. ( Desborough, MJR; Doree, C; Lowe, GC; Obaji, S; Thomas, W, 2021)
" To control the hemorrhagic diathesis, we commenced combination therapy for DIC with danaparoid (1,250 Ux2/day, intravenously (IV)) and tranexamic acid (0."3.73Kasabach-Merritt syndrome associated with giant liver hemangioma: the effect of combined therapy with danaparoid sodium and tranexamic acid. ( Asakura, H; Matsui, O; Nakao, S; Omote, M; Ontachi, Y; Yoshida, T, 2005)
"Tranexamic acid has been advocated for patients with severe bleeding tendency due to thrombocytopenia not responding to platelet transfusions."3.69Microscopic haematuria as a relative contraindication for tranexamic acid. ( Schultz, M; van der Lelie, H, 1995)
"The morbidity and mortality of postpartum hemorrhage (PPH) in women with an underlying bleeding disorder requires vigilance by the hematologist."2.52An update on the management of bleeding disorders during pregnancy. ( Kouides, PA, 2015)
"Tranexamic acid was administered for menorrhagia and resumed later for labor and continued into the postpartum period since antifibrinolytics have been the mainstay in the management of PAI-1 deficiency."1.56The utility of thromboelastography and tranexamic acid in plasminogen activator inhibitor deficiency during pregnancy: a rare case report. ( Hammer, RD; Laziuk, K; Prabhakaran, N, 2020)
"Medroxyprogesterone acetate treatment for her dysfunctional uterine bleeding was unsuccessful."1.32Menorrhagia due to a qualitative deficiency of plasminogen activator inhibitor-1: case report and literature review. ( Osswald, M; Repine, T, 2004)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's3 (15.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Jain, S1
Acharya, SS1
Prabhakaran, N1
Laziuk, K1
Hammer, RD1
MacDonald, S1
Wright, A1
Beuche, F1
Downes, K1
Besser, M1
Symington, E1
Kelly, A1
Thomas, W2
Desborough, MJR1
Obaji, S1
Lowe, GC1
Doree, C1
Charpentier, V1
Ives, ST1
Nogami, K1
Matsumoto, T1
Sasai, K1
Ogiwara, K1
Arai, N1
Shima, M1
Davis, A1
Walsh, M1
McCarthy, P1
Brown, G1
Roberts, S1
Tran, H1
Street, A1
Fong, CY1
Kemp, W1
Faraoni, D1
Rozen, L1
Willems, A1
Torres, CS1
Pereira, LM1
Demulder, A1
Van der Linden, P1
Kouides, PA1
Repine, T1
Osswald, M1
Ontachi, Y1
Asakura, H1
Omote, M1
Yoshida, T1
Matsui, O1
Nakao, S1
Yoshioka, A1
Kamitsuji, H1
Takase, T1
Iida, Y1
Tsukada, S1
Mikami, S1
Fukui, H1
Schultz, M1
van der Lelie, H1
Meijer, K1
Smid, WM1
Geerards, S1
van der Meer, J1
Levi, M1
Peters, M1
Briët, E2
Favier, R1
Aoki, N1
de Moerloose, P1
Edlund, M1
Blombäck, M1
Fried, G1
Stavem, P1
Hjort, PF1
Eikenboom, JC1
van der Meer, FJ1
Leebeek, FW1
Knot, EA1
Kluft, C1

Reviews

6 reviews available for tranexamic acid and Hemorrhagic Disorders

ArticleYear
Inherited disorders of the fibrinolytic pathway.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2019, Volume: 58, Issue:5

    Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Blood Platelets; Factor V Deficiency; Fibrinolysis; He

2019
Management of surgery, menorrhagia and child-birth for patients with unclassified bleeding disorders: a systematic review of cohort studies.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Sep-01, Volume: 32, Issue:6

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Deamino Arginine Vasopressin; Disease Manageme

2021
An update on the management of bleeding disorders during pregnancy.
    Current opinion in hematology, 2015, Volume: 22, Issue:5

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Female; Hemorrhagic

2015
[Blind spots of the diagnostic hemostasis screen].
    Nederlands tijdschrift voor geneeskunde, 2000, Mar-04, Volume: 144, Issue:10

    Topics: Adult; alpha-2-Antiplasmin; Antifibrinolytic Agents; Blood Coagulation Tests; Child; Diagnosis, Diff

2000
Congenital alpha(2)-plasmin inhibitor deficiencies: a review.
    British journal of haematology, 2001, Volume: 114, Issue:1

    Topics: alpha-2-Antiplasmin; Aminocaproates; Antifibrinolytic Agents; Fibrinolysis; Hemorrhagic Disorders; H

2001
[Congenital deficiency of the fibrinolysis inhibitor alpha 2-antiplasmin as a cause of hemorrhagic diathesis].
    Nederlands tijdschrift voor geneeskunde, 1988, Jan-23, Volume: 132, Issue:4

    Topics: Adult; alpha-2-Antiplasmin; Hemorrhagic Disorders; Humans; Male; Tranexamic Acid

1988

Trials

3 trials available for tranexamic acid and Hemorrhagic Disorders

ArticleYear
Characterization of a large cohort of patients with unclassified bleeding disorder; clinical features, management of haemostatic challenges and use of global haemostatic assessment with proposed recommendations for diagnosis and treatment.
    International journal of laboratory hematology, 2020, Volume: 42, Issue:2

    Topics: Adult; Aged; Deamino Arginine Vasopressin; Female; Hemorrhagic Disorders; Humans; Male; Middle Aged;

2020
Tranexamic acid without prophylactic factor replacement for prevention of bleeding in hereditary bleeding disorder patients undergoing endoscopy: a pilot study.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2013, Volume: 19, Issue:4

    Topics: Adult; Aged; Biopsy; Blood Coagulation Factors; Blood Loss, Surgical; Demography; Endoscopy; Female;

2013
Desmopressin in the treatment of menorrhagia in women with no common coagulation factor deficiency but with prolonged bleeding time.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2002, Volume: 13, Issue:3

    Topics: Adult; Bleeding Time; Cross-Over Studies; Deamino Arginine Vasopressin; Double-Blind Method; Female;

2002

Other Studies

11 other studies available for tranexamic acid and Hemorrhagic Disorders

ArticleYear
The utility of thromboelastography and tranexamic acid in plasminogen activator inhibitor deficiency during pregnancy: a rare case report.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2020, Volume: 31, Issue:1

    Topics: Adult; Female; Hemorrhagic Disorders; Humans; Plasminogen Activator Inhibitor 1; Pregnancy; Thrombel

2020
Hyperfibrinolysis: An Uncommon Cause of Bleeding in Cirrhosis.
    The American journal of medicine, 2022, Volume: 135, Issue:1

    Topics: Antifibrinolytic Agents; Hemorrhagic Disorders; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Age

2022
A novel simultaneous clot-fibrinolysis waveform analysis for assessing fibrin formation and clot lysis in haemorrhagic disorders.
    British journal of haematology, 2019, Volume: 187, Issue:4

    Topics: Arginine; Fibrin; Fibrin Clot Lysis Time; Fibrinolysis; Hemorrhagic Disorders; Humans; Kinetics; Pip

2019
Experimental model of hyperfibrinolysis designed for rotational thromboelastometry in children with congenital heart disease.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:3

    Topics: Antifibrinolytic Agents; Child; Child, Preschool; Fibrinolysis; Heart Defects, Congenital; Hemorrhag

2015
Menorrhagia due to a qualitative deficiency of plasminogen activator inhibitor-1: case report and literature review.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2004, Volume: 10, Issue:3

    Topics: Adult; Anemia, Iron-Deficiency; Antifibrinolytic Agents; Blood Coagulation Tests; Female; Hemorrhagi

2004
Kasabach-Merritt syndrome associated with giant liver hemangioma: the effect of combined therapy with danaparoid sodium and tranexamic acid.
    Haematologica, 2005, Volume: 90 Suppl

    Topics: Adult; Antifibrinolytic Agents; Blood Proteins; Chondroitin Sulfates; Dermatan Sulfate; Disseminated

2005
Congenital deficiency of alpha 2-plasmin inhibitor in three sisters.
    Haemostasis, 1982, Volume: 11, Issue:3

    Topics: alpha-2-Antiplasmin; Blood Coagulation Tests; Blood Transfusion; Child, Preschool; Female; Fibrinoly

1982
Microscopic haematuria as a relative contraindication for tranexamic acid.
    British journal of haematology, 1995, Volume: 89, Issue:3

    Topics: Adult; Contraindications; Female; Hematuria; Hemorrhagic Disorders; Humans; Male; Middle Aged; Throm

1995
Hyperfibrinogenolysis in disseminated adenocarcinoma.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Adult; Afibrinogenemia; alpha-2-Antiplasmin; Antifibrinolytic Agents; Brain Ischemia

1998
[Treatment of hemorrhagic diathesis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Oct-10, Volume: 95, Issue:28

    Topics: Blood Transfusion; Hemorrhagic Disorders; Humans; Norepinephrine; Plasma; Prednisone; Splenectomy; T

1975
Acquired von Willebrand's disease due to excessive fibrinolysis.
    British journal of haematology, 1992, Volume: 81, Issue:4

    Topics: Blood Coagulation Disorders; Fibrinolysis; Hemorrhagic Disorders; Humans; Male; Middle Aged; Tranexa

1992