tranexamic acid has been researched along with Hemorrhage, Intracranial, Traumatic in 8 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tranexamic acid (TXA) has been shown to reduce blood loss in surgical patients and the risk of death in patients with traumatic bleeding, with no apparent increase in vascular occlusive events." | 2.77 | CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial. ( Al-Shahi Salman, R; Kawahara, T; Morris, Z; Perel, P; Prieto-Merino, D; Roberts, I; Sandercock, P; Shakur, H; Wardlaw, J, 2012) |
| "Tranexamic acid was identified by univariate analysis as an independent factor associated with lower mortality in cerebral contusions or traumatic subarachnoid hemorrhage." | 1.51 | Improving Survival with Tranexamic Acid in Cerebral Contusions or Traumatic Subarachnoid Hemorrhage: Univariate and Multivariate Analysis of Independent Factors Associated with Lower Mortality. ( Chan, DYC; Cheng, KKF; Ho, WWS; Leung, GKK; Li, LF; Lui, WM; Pu, JKS; Taw, BBT; Tsang, ACO; Tsang, FCP, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, A | 1 |
| Trivedi, R | 1 |
| Ahmed, N | 1 |
| Ghawnni, A | 1 |
| Coates, A | 1 |
| Owen, J | 1 |
| Mahmood, A | 1 |
| Roberts, I | 2 |
| Shakur, H | 2 |
| Chan, DYC | 1 |
| Tsang, ACO | 1 |
| Li, LF | 1 |
| Cheng, KKF | 1 |
| Tsang, FCP | 1 |
| Taw, BBT | 1 |
| Pu, JKS | 1 |
| Ho, WWS | 1 |
| Lui, WM | 1 |
| Leung, GKK | 1 |
| Valle, EJ | 1 |
| Allen, CJ | 1 |
| Van Haren, RM | 1 |
| Jouria, JM | 1 |
| Li, H | 1 |
| Livingstone, AS | 1 |
| Namias, N | 1 |
| Schulman, CI | 1 |
| Proctor, KG | 1 |
| Perel, P | 1 |
| Al-Shahi Salman, R | 1 |
| Kawahara, T | 1 |
| Morris, Z | 1 |
| Prieto-Merino, D | 1 |
| Sandercock, P | 1 |
| Wardlaw, J | 1 |
| Grassetto, A | 1 |
| Saggioro, D | 1 |
| Caputo, P | 1 |
| Penzo, D | 1 |
| Bossi, A | 1 |
| Tedesco, M | 1 |
| Maggiolo, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tranexamic Acid for the Treatment of Significant Traumatic Brain Injury: an International Randomised, Double Blind Placebo Controlled Trial[NCT01402882] | Phase 3 | 12,737 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tranexamic acid and Hemorrhage, Intracranial, Traumatic
| Article | Year |
|---|---|
Therapeutic Strategies in Traumatic Intracranial Hemorrhage and Outcomes.
Topics: Hemorrhage; Humans; Intracranial Hemorrhage, Traumatic; Risk Factors; Tranexamic Acid | 2023 |
5 trials available for tranexamic acid and Hemorrhage, Intracranial, Traumatic
| Article | Year |
|---|---|
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.
Topics: Adult; Aged; Antifibrinolytic Agents; Brain Injuries, Traumatic; Drug Administration Schedule; Femal | 2019 |
Compliance of tranexamic acid administration to trauma patients at a level-one trauma centre.
Topics: Antifibrinolytic Agents; Brain Injuries; Dose-Response Relationship, Drug; Follow-Up Studies; Humans | 2018 |
A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding M
Topics: Antifibrinolytic Agents; Brain Injuries, Traumatic; Brain Ischemia; Clinical Protocols; Double-Blind | 2017 |
Do all trauma patients benefit from tranexamic acid?
Topics: Adult; Antifibrinolytic Agents; Brain Injuries; Dose-Response Relationship, Drug; Double-Blind Metho | 2014 |
CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial.
Topics: Adult; Anti-Arrhythmia Agents; Antifibrinolytic Agents; Female; Glasgow Coma Scale; Humans; Intracra | 2012 |
2 other studies available for tranexamic acid and Hemorrhage, Intracranial, Traumatic
| Article | Year |
|---|---|
Improving Survival with Tranexamic Acid in Cerebral Contusions or Traumatic Subarachnoid Hemorrhage: Univariate and Multivariate Analysis of Independent Factors Associated with Lower Mortality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Contusion; Cerebral Hemorrhage, Traumatic; Female; | 2019 |
Rotational thromboelastometry analysis and management of life-threatening haemorrhage in isolated craniofacial injury.
Topics: Aged; Blood Coagulation Factors; Blood Component Transfusion; Blood Gas Analysis; Blood Platelets; F | 2012 |