Page last updated: 2024-11-05

tranexamic acid and Hematoma

tranexamic acid has been researched along with Hematoma in 64 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Hematoma: A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue.

Research Excerpts

ExcerptRelevanceReference
" Tranexamic acid (TXA) is an antifibrinolytic drug potentially limiting hematoma expansion."9.69Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial. ( Barinka, F; Baumgartner, P; Bonati, LH; De Marchis, GM; Engelter, ST; Fischer, U; Gensicke, H; Guzman, R; Kägi, G; Karwacki, GM; Lyrer, PA; Maurer, M; Nedeltchev, K; Nickel, CH; Peters, N; Polymeris, AA; Schaedelin, S; Seiffge, DJ; Siepen, BM; Sprigg, N; Stippich, C; Thilemann, S; Traenka, C; Tsakiris, DA; Vehoff, J; Wagner, B; Wegener, S; Z'Graggen, WJ, 2023)
"This study aims to illustrate the impact of applying the tranexamic acid impregnated in a gelatin sponge between the anterior rectus sheath and the Rectus Abdominis muscle during Cesarean section (CS) in minimizing rectus sheath hematoma (RHS) in women treated with Warfarin."9.69Role of tranexamic acid-soaked gelatin sponge in minimizing rectus sheath hematoma after cesarean section in women treated with warfarin, a simple tool for high-risk cases, a randomized controlled trial. ( Hany, A; Mansour, A; Nabil, M; Sediek, M, 2023)
"This prospective nested magnetic resonance imaging (MRI) substudy of a randomized clinical trial (RCT) recruited participants from the multicenter, double-blind, placebo-controlled, phase 3 RCT (Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage [TICH-2]) from July 1, 2015, to September 30, 2017, and conducted follow-up to 90 days after participants were randomized to either the tranexamic acid or placebo group."9.51Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial. ( Al-Shahi Salman, R; Bath, PM; Casado, AM; Dineen, RA; England, TJ; Gallagher, R; Law, ZK; Morgan, PS; Pszczolkowski, S; Roberts, I; Sprigg, N; Swienton, D; Werring, DJ; Woodhouse, LJ, 2022)
"Evidence-based medicine was used to evaluate the efficacy and safety of tranexamic acid in patients with intracerebral hemorrhage."9.41Tranexamic acid in intracerebral hemorrhage: a meta-analysis. ( Ling, L; Yu, Z, 2023)
"Data from the TICH-2 trial do not support that admission spot sign status modifies the treatment effect of tranexamic acid versus placebo in patients with acute intracerebral hemorrhage."9.41Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign. ( Bath, PM; Christensen, H; Christensen, LM; Dineen, RA; Flaherty, K; Gluud, C; Jakobsen, JC; Law, Z; Overgaard, K; Ovesen, C; Rasmussen, RS; Sprigg, N; Steiner, T, 2021)
"The effects of tranexamic acid on spontaneous intracerebral hemorrhage in reducing hematoma expansion and mortality as well as its role in thromboembolic complications and in the improvement of functional outcomes remain substantially uncertain."9.12Tranexamic Acid for Adult Patients with Spontaneous Intracerebral Hemorrhage: A Systematic Review with Meta-analysis. ( Ma, L; Song, J; Wang, X; You, C, 2021)
"A randomized double-blind trial has shown that, in 160 women with breast cancer undergoing lumpectomy or mastectomy with axillary clearance, perioperative and postoperative administration of tranexamic acid 1 g three times daily resulted in a significant reduction in the mean postoperative drainage volume compared with patients given placebo (283 versus 432 ml, P < 0."9.07Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer. ( Haberthuer, F; Harder, F; Kreuter, U; Laffer, U; Oertli, D, 1994)
"Intravenous tranexamic acid safely reduces risk of hematoma in implant-based breast reconstruction."7.96Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events. ( Banuelos, J; Harless, CA; Jacobson, SR; Manrique, OJ; Martinez-Jorge, J; Nguyen, MT; Tran, NV; Weissler, JM, 2020)
"prothrombin complex concentrate and fresh-frozen plasma effectively prevent hematoma growth in murine warfarin-associated intracerebral hemorrhage, whereas Factor VIIa was less effective."7.77Comparative effectiveness of hemostatic therapy in experimental warfarin-associated intracerebral hemorrhage. ( Heiland, S; Illanes, S; Schwarting, S; Veltkamp, R; Zhou, W, 2011)
"No tranexamic acid was administered to the control group."7.30[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study]. ( Hrabálek, L; Jablonský, J; Novák, V; Stejskal, P; Trnka, Š; Wanek, T, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic agent, which has shown an effect on reducing blood loss in many diseases."6.72Tranexamic Acid Inhibits Hematoma Expansion in Intracerebral Hemorrhage and Traumatic Brain Injury. Does Blood Pressure Play a Potential Role? A Meta-Analysis from Randmized Controlled Trials. ( Chen, Z; Gao, B; Rong, X; Wang, Z; Xue, T; Yang, Y, 2021)
"The use of IV TXA is a safe and effective way to reduce hematoma rates in patients receiving reduction mammoplasty."5.91The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates. ( Kebede, S; Losken, A; Marxen, T; Om, A, 2023)
"Tranexamic acid (TXA) has gained increasing recognition as a valuable pharmacologic agent within plastic surgery."5.72Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty. ( Alsayed, A; Antezana, L; Banuelos, J; Curiel, D; Harless, CA; Kerivan, L; Kuruoglu, D; Martinez-Jorge, J; Nguyen, MT; Sharaf, BA; Tran, NV; Vijayasekaran, A; Weissler, JM, 2022)
"In this trial, the median size of post-kidney biopsy hematoma was unexpectedly larger in the high-dose tranexamic acid group than in the placebo group."5.69Intravenous Tranexamic Acid in Percutaneous Kidney Biopsy: A Randomized Controlled Trial. ( Izawa, J; Katsuren, M; Kawamura, T; Matsuzaki, K; Miyasato, H; Nishioka, N; Ohigashi, T; Raita, Y; Sozu, T; Sudo, K; Uehara, G; Yano, H, 2023)
" Tranexamic acid (TXA) is an antifibrinolytic drug potentially limiting hematoma expansion."5.69Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial. ( Barinka, F; Baumgartner, P; Bonati, LH; De Marchis, GM; Engelter, ST; Fischer, U; Gensicke, H; Guzman, R; Kägi, G; Karwacki, GM; Lyrer, PA; Maurer, M; Nedeltchev, K; Nickel, CH; Peters, N; Polymeris, AA; Schaedelin, S; Seiffge, DJ; Siepen, BM; Sprigg, N; Stippich, C; Thilemann, S; Traenka, C; Tsakiris, DA; Vehoff, J; Wagner, B; Wegener, S; Z'Graggen, WJ, 2023)
"This study aims to illustrate the impact of applying the tranexamic acid impregnated in a gelatin sponge between the anterior rectus sheath and the Rectus Abdominis muscle during Cesarean section (CS) in minimizing rectus sheath hematoma (RHS) in women treated with Warfarin."5.69Role of tranexamic acid-soaked gelatin sponge in minimizing rectus sheath hematoma after cesarean section in women treated with warfarin, a simple tool for high-risk cases, a randomized controlled trial. ( Hany, A; Mansour, A; Nabil, M; Sediek, M, 2023)
"Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units (STOP-MSU) is a phase II double-blind, randomised, placebo-controlled, multicentre, international investigator-led clinical trial, conducted within the estimand statistical framework."5.51Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial. ( Brown, H; Campbell, BCV; Cheung, A; Cho, DY; Choi, P; Churilov, L; Clissold, B; Cloud, GC; Dang, DP; Davis, SM; Donnan, GA; Grimley, R; Hsu, CY; Jeng, JS; Kleinig, T; Levi, C; Ma, H; Mahawish, K; Meretoja, A; Mitchell, PJ; Nguyen, HT; Parsons, MW; Phuong, NTM; Ranta, A; Sanders, L; Shah, D; Sharma, G; Spratt, N; Ton, MD; Wang, HK; Worthington, J; Wu, T; Yan, B; Yassi, N; Yogendrakumar, V; Zhao, H, 2022)
"This prospective nested magnetic resonance imaging (MRI) substudy of a randomized clinical trial (RCT) recruited participants from the multicenter, double-blind, placebo-controlled, phase 3 RCT (Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage [TICH-2]) from July 1, 2015, to September 30, 2017, and conducted follow-up to 90 days after participants were randomized to either the tranexamic acid or placebo group."5.51Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial. ( Al-Shahi Salman, R; Bath, PM; Casado, AM; Dineen, RA; England, TJ; Gallagher, R; Law, ZK; Morgan, PS; Pszczolkowski, S; Roberts, I; Sprigg, N; Swienton, D; Werring, DJ; Woodhouse, LJ, 2022)
"Evidence-based medicine was used to evaluate the efficacy and safety of tranexamic acid in patients with intracerebral hemorrhage."5.41Tranexamic acid in intracerebral hemorrhage: a meta-analysis. ( Ling, L; Yu, Z, 2023)
"Data from the TICH-2 trial do not support that admission spot sign status modifies the treatment effect of tranexamic acid versus placebo in patients with acute intracerebral hemorrhage."5.41Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign. ( Bath, PM; Christensen, H; Christensen, LM; Dineen, RA; Flaherty, K; Gluud, C; Jakobsen, JC; Law, Z; Overgaard, K; Ovesen, C; Rasmussen, RS; Sprigg, N; Steiner, T, 2021)
"To determine the effect of Intravenous Tranexamic Acid (TXA) on traumatic intracerebral hemorrhage."5.41Effect of Intravenous Tranexamic Acid on Intracerebral Brain Hemorrhage in Traumatic Brain Injury. ( Farrahi, P; Marandi, HJ; Rasras, S; Safari, H; Zeinali, M, 2021)
"Systemic administration of TXA can effectively reduce the postoperative blood loss which results in lower rate of transfusion requirement and wound hematoma in minimally invasive TKA patients when rivaroxaban is used for thromboprophylaxis."5.24The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial. ( Chen, B; Huang, CC; Kuo, FC; Lin, PC; Wang, JW; Yen, SH, 2017)
"Our study showed no clinical benefit or disadvantage to closed suction drainage in anterior hip arthroplasty with the concomitant use of tranexamic acid for surgical hemostasis and aspirin for venous thromboembolism prophylaxis."5.22Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial. ( Barksdale, LC; Calvo, C; McNamara, CA; Patel, PD; Suarez, JC; Szubski, CR, 2016)
"This is the first trial to evaluate the efficacy of tranexamic acid in intracerebral hemorrhage patients selected based on an imaging biomarker of high likelihood of hematoma growth."5.19The spot sign and tranexamic acid on preventing ICH growth--AUStralasia Trial (STOP-AUST): protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial. ( Anderson, CS; Aviv, RI; Barras, C; Bladin, C; Campbell, BC; Churilov, L; Davis, SM; Delcourt, C; Donnan, GA; Jannes, J; Kleinig, T; Lee, A; Levi, C; Mahant, N; Markus, R; Meretoja, A; Mitchell, P; Nandurkar, H; Parsons, MW; Rupasinghe, J; Spratt, NJ; Sturm, J; Wijeratne, T; Yan, B; Yassi, N; Zavala, J, 2014)
"The effects of tranexamic acid on spontaneous intracerebral hemorrhage in reducing hematoma expansion and mortality as well as its role in thromboembolic complications and in the improvement of functional outcomes remain substantially uncertain."5.12Tranexamic Acid for Adult Patients with Spontaneous Intracerebral Hemorrhage: A Systematic Review with Meta-analysis. ( Ma, L; Song, J; Wang, X; You, C, 2021)
"A randomized double-blind trial has shown that, in 160 women with breast cancer undergoing lumpectomy or mastectomy with axillary clearance, perioperative and postoperative administration of tranexamic acid 1 g three times daily resulted in a significant reduction in the mean postoperative drainage volume compared with patients given placebo (283 versus 432 ml, P < 0."5.07Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer. ( Haberthuer, F; Harder, F; Kreuter, U; Laffer, U; Oertli, D, 1994)
"The purpose of this study was to explore efficacy of locally injected tranexamic acid (TXA) at a concentration of 1 mg/mL for reduction perioperative bleeding and postoperative complications in subcutaneous tumor excisions."4.31Efficacy of local infiltration of tranexamic acid in subcutaneous surgery: A protocol from a single medical center. ( Chang, YJ; Lin, HC; Lin, YH; Wang, PL, 2023)
"Intravenous tranexamic acid safely reduces risk of hematoma in implant-based breast reconstruction."3.96Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events. ( Banuelos, J; Harless, CA; Jacobson, SR; Manrique, OJ; Martinez-Jorge, J; Nguyen, MT; Tran, NV; Weissler, JM, 2020)
"prothrombin complex concentrate and fresh-frozen plasma effectively prevent hematoma growth in murine warfarin-associated intracerebral hemorrhage, whereas Factor VIIa was less effective."3.77Comparative effectiveness of hemostatic therapy in experimental warfarin-associated intracerebral hemorrhage. ( Heiland, S; Illanes, S; Schwarting, S; Veltkamp, R; Zhou, W, 2011)
"No tranexamic acid was administered to the control group."3.30[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study]. ( Hrabálek, L; Jablonský, J; Novák, V; Stejskal, P; Trnka, Š; Wanek, T, 2023)
"Its role in reducing postoperative blood loss in breast surgery remains unclear."3.01The Effects of Tranexamic Acid in Breast Surgery: A Systematic Review and Meta-Analysis. ( Huynh, MNQ; McRae, MC; McRae, MH; Voineskos, S; Wong, CR, 2023)
"Data from the Tranexamic acid in IntraCerebral Hemorrhage-2 (TICH-2) randomized controlled trial were analyzed."3.01Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial. ( Appleton, JP; Bath, PM; Bereczki, D; Cala, L; Ciccone, A; Dineen, R; England, TJ; Law, ZK; Mistri, AK; Ozturk, S; Sprigg, N, 2021)
"Tranexamic acid (TXA) is an antifibrinolytic agent, which has shown an effect on reducing blood loss in many diseases."2.72Tranexamic Acid Inhibits Hematoma Expansion in Intracerebral Hemorrhage and Traumatic Brain Injury. Does Blood Pressure Play a Potential Role? A Meta-Analysis from Randmized Controlled Trials. ( Chen, Z; Gao, B; Rong, X; Wang, Z; Xue, T; Yang, Y, 2021)
"Tranexamic acid was given at the end of the operation and 3 hours later."2.69Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty. ( Benoni, G; Fredin, H; Lethagen, S; Nilsson, P, 2000)
"The use of IV TXA is a safe and effective way to reduce hematoma rates in patients receiving reduction mammoplasty."1.91The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates. ( Kebede, S; Losken, A; Marxen, T; Om, A, 2023)
"Tranexamic acid (TXA) has shown to significantly reduce perioperative blood loss in elective orthopedic joint replacement surgery but is yet not implemented in acute hip fracture surgery for elderly patients who are particularly vulnerable to perioperative blood loss and postoperative anemia."1.72Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients. ( de Jong, L; Kuijper, TM; Roukema, GR; van Rijckevorsel, VAJIM, 2022)
"Tranexamic acid (TXA) has gained increasing recognition as a valuable pharmacologic agent within plastic surgery."1.72Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty. ( Alsayed, A; Antezana, L; Banuelos, J; Curiel, D; Harless, CA; Kerivan, L; Kuruoglu, D; Martinez-Jorge, J; Nguyen, MT; Sharaf, BA; Tran, NV; Vijayasekaran, A; Weissler, JM, 2022)
"Acquired haemophilia A is a rare but important diagnosis, carrying a mortality rate of 22%."1.56 ( Howden, WB; Kam, J; Leith, N; Singh, S, 2020)
"A young girl with constant exotropia was planned for surgery."1.51Factor XIII deficiency leading to preseptal haematoma post-strabismus surgery. ( Badakere, A; Jain, M; Kekunnaya, R, 2019)
"Fibrinogen level was normalized within two days (2."1.43Primary hyperfibrinolysis as the presenting sign of prostate cancer: A case report. ( Cvetković, Z; Kulić, A; Libek, V, 2016)
"Glanzmann's thrombasthenia (GT) is a very rare autosomal recessive genetic bleeding disorder."1.38Giant abdominopelvic haematoma arising from ovulation in a Glanzmann's thrombasthenia patient with platelet refractoriness: treatment with surgery and intra-abdominal tranexamic acid. ( Bektas, O; Boyraz, G; Buyukasik, Y; Selcuk Tuncer, Z; Selcuk, I, 2012)
"Immediately after diagnosis of intracerebral hemorrhage on computed tomographic scan, 156 patients who were admitted within 24 hours of onset were treated with either a combination of PAF and BPC (PAF group) or a combination of RAF and BPC (RAF group)."1.33Rapid administration of antifibrinolytics and strict blood pressure control for intracerebral hemorrhage. ( Fujii, Y; Morita, K; Sorimachi, T; Tanaka, R, 2005)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.13)18.7374
1990's5 (7.81)18.2507
2000's7 (10.94)29.6817
2010's15 (23.44)24.3611
2020's35 (54.69)2.80

Authors

AuthorsStudies
Laikhter, E1
Comer, CD1
Shiah, E1
Manstein, SM1
Bain, PA1
Lin, SJ1
Wang, X2
Ma, L1
Song, J1
You, C1
Yassi, N2
Zhao, H1
Churilov, L2
Campbell, BCV1
Wu, T1
Ma, H1
Cheung, A1
Kleinig, T2
Brown, H1
Choi, P1
Jeng, JS1
Ranta, A1
Wang, HK1
Cloud, GC1
Grimley, R1
Shah, D1
Spratt, N1
Cho, DY1
Mahawish, K1
Sanders, L1
Worthington, J1
Clissold, B1
Meretoja, A2
Yogendrakumar, V1
Ton, MD1
Dang, DP1
Phuong, NTM1
Nguyen, HT1
Hsu, CY1
Sharma, G1
Mitchell, PJ1
Yan, B2
Parsons, MW2
Levi, C2
Donnan, GA2
Davis, SM2
Albanese, R1
Zingaretti, N1
Almesberger, D1
Parodi, PC1
Weissler, JM2
Kuruoglu, D1
Antezana, L1
Curiel, D1
Kerivan, L1
Alsayed, A1
Banuelos, J2
Harless, CA2
Sharaf, BA1
Vijayasekaran, A1
Martinez-Jorge, J2
Tran, NV2
Nguyen, MT2
van Rijckevorsel, VAJIM1
Roukema, GR1
Kuijper, TM1
de Jong, L1
Pszczolkowski, S2
Sprigg, N6
Woodhouse, LJ1
Gallagher, R1
Swienton, D1
Law, ZK3
Casado, AM1
Roberts, I1
Werring, DJ1
Al-Shahi Salman, R1
England, TJ3
Morgan, PS1
Bath, PM5
Dineen, RA4
Fernau, J1
Zhang, Z2
Guan, X1
Li, Z1
Xin, M1
Izawa, J1
Matsuzaki, K1
Raita, Y1
Uehara, G1
Nishioka, N1
Yano, H1
Sudo, K1
Katsuren, M1
Ohigashi, T1
Sozu, T1
Kawamura, T1
Miyasato, H1
Baker, DM1
Jacob, L1
Busuttil, A1
Ye, L1
Guan, J1
Chen, X1
Lu, H1
Xiao, Y1
Dai, X1
Wu, M1
Ma, S1
Sun, X1
Li, L1
Tan, Y2
Xia, Y1
Calpin, GG1
McAnena, PF1
Davey, MG1
Calpin, P1
Kerin, MJ1
McInerney, N1
Walsh, SR1
Lowery, AJ1
Liechti, R1
van de Wall, BJM1
Hug, U1
Fritsche, E1
Franchi, A1
Om, A1
Marxen, T1
Kebede, S1
Losken, A1
Safran, T1
Vorstenbosch, J1
Viezel-Mathieu, A1
Davison, P1
Dionisopoulos, T1
Huynh, MNQ1
Wong, CR1
McRae, MC1
Voineskos, S1
McRae, MH1
Sipos, K1
Kämäräinen, S1
Kauhanen, S1
Stejskal, P1
Trnka, Š1
Hrabálek, L1
Wanek, T1
Jablonský, J1
Novák, V1
Polymeris, AA1
Karwacki, GM1
Siepen, BM1
Schaedelin, S1
Tsakiris, DA1
Stippich, C1
Guzman, R1
Nickel, CH1
Kägi, G1
Vehoff, J1
Barinka, F1
Thilemann, S1
Maurer, M1
Wagner, B1
Traenka, C1
Gensicke, H1
De Marchis, GM1
Bonati, LH1
Fischer, U1
Z'Graggen, WJ1
Nedeltchev, K1
Wegener, S1
Baumgartner, P1
Engelter, ST1
Seiffge, DJ1
Peters, N1
Lyrer, PA1
Chang, YJ1
Lin, YH1
Wang, PL1
Lin, HC1
Hany, A1
Mansour, A1
Sediek, M1
Nabil, M1
Jain, M1
Kekunnaya, R1
Badakere, A1
Ali, A1
Krishnan, K1
Bischoff, A1
Appleton, JP2
Scutt, P1
Woodhouse, L1
Cala, LA1
Ozturk, S2
Roffe, C1
Bereczki, D2
Ciccone, A2
Christensen, H3
Ovesen, C3
Howden, WB1
Kam, J1
Leith, N1
Singh, S1
Jacobson, SR1
Manrique, OJ1
Myckatyn, TM1
Tenenbaum, MM1
Dineen, R1
Cala, L1
Mistri, AK1
Jiang, C1
Wang, J2
Zhang, J1
Gao, B1
Xue, T1
Rong, X1
Yang, Y1
Wang, Z2
Chen, Z1
Hayward, CPM1
Tasneem, S1
Rivard, GE1
Safari, H1
Farrahi, P1
Rasras, S1
Marandi, HJ1
Zeinali, M1
Burton, H1
Mossadegh, S1
McCarthy, R1
Liu, J1
Nie, X1
Gu, H1
Zhou, Q1
Sun, H1
Liu, D1
Zheng, L1
Zhao, J1
Wang, Y2
Cao, Y1
Zhu, H1
Zhang, Y1
Yi, L1
Pu, Y1
Wen, M1
Yang, Z1
Sun, S1
Wang, W1
Zhao, X1
Liu, L1
Jakobsen, JC2
Gluud, C2
Steiner, T2
Law, Z2
Flaherty, K2
Christensen, LM1
Overgaard, K1
Rasmussen, RS1
Yu, Z1
Ling, L1
Kulić, A1
Cvetković, Z1
Libek, V1
Donnan, G1
Davis, S1
Jiang, W1
Shang, L1
Knight, H1
Banks, J1
Muchmore, J1
Ives, C1
Green, M1
Campbell, BC1
Aviv, RI1
Barras, C1
Mitchell, P1
Nandurkar, H1
Bladin, C1
Wijeratne, T1
Spratt, NJ1
Jannes, J1
Sturm, J1
Rupasinghe, J1
Zavala, J1
Lee, A1
Markus, R1
Delcourt, C1
Mahant, N1
Anderson, CS1
Remérand, F2
Cotten, M1
N'Guessan, YF1
Couvret, C2
Rosset, P2
Favard, L1
Laffon, M2
Fusciardi, J2
Fisher, C1
Mo, A1
Warrillow, S1
Smith, C1
Jones, D1
Suarez, JC1
McNamara, CA1
Barksdale, LC1
Calvo, C1
Szubski, CR1
Patel, PD1
Beton, O1
Saricam, E1
Kaya, H1
Yucel, H1
Dogdu, O1
Turgut, OO1
Berkan, O1
Tandogan, I1
Yilmaz, MB1
Wang, JW1
Chen, B1
Lin, PC1
Yen, SH1
Huang, CC1
Kuo, FC1
Amissah-Arthur, KN1
Groppe, M1
Scotcher, S1
Illanes, S1
Zhou, W1
Schwarting, S1
Heiland, S1
Veltkamp, R1
Chevet, I1
Baud, A1
Pouplard, C1
Buyukasik, Y1
Boyraz, G1
Selcuk, I1
Bektas, O1
Selcuk Tuncer, Z1
Yasui, H1
Adachi, Y1
Minami, T1
Ishida, T1
Kato, Y1
Imai, K1
Sorimachi, T1
Fujii, Y1
Morita, K1
Tanaka, R1
Coetzee, MJ1
Hoshino, Y1
Hatake, K1
Muroi, K1
Tsunoda, S1
Suzuki, T1
Miwa, A1
Sakamoto, S1
Miura, Y1
Oertli, D1
Laffer, U1
Haberthuer, F1
Kreuter, U1
Harder, F1
Miyauchi, Y2
Mii, Y2
Aoki, M1
Tamai, S2
Takahashi, Y2
Yoshioka, A2
Panula, K1
Oikarinen, K1
Vujkovac, B1
Sabovic, M1
Benoni, G1
Lethagen, S1
Nilsson, P1
Fredin, H1
van Rijn, RS1
Verdonck, LF1
Tanaka, T1
Nakajima, N1
Fukui, H1
Takahashi, H1
Koike, T1
Yoshida, N1
Kitahara, O1
Hanano, M1
Shibata, A1
Aoki, N1
Pickard, JD1
Walker, V1
Vile, J1
Perry, S1
Smythe, PJ1
Hunt, R1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of TRanEXamic Acid in Reduction Mammoplasty (TREX-ARM): a Double-blinded Randomized Controlled Trial[NCT04947514]Phase 498 participants (Actual)Interventional2021-10-29Completed
Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage[NCT05554211]Phase 230 participants (Anticipated)Interventional2022-07-12Recruiting
Efficacy of Tranexamic Acid in Femoral Shaft Fractures Osteosynthesis; A Double Blind Randomized Controlled Trial[NCT04803591]Phase 40 participants (Actual)Interventional2021-08-01Withdrawn (stopped due to Not approved by Ethics Commettee)
Effects of Tranexamic Acid for Alloplastic Breast Reconstruction: A Randomized Control Trial[NCT04918589]Phase 3106 participants (Anticipated)Interventional2022-08-31Not yet recruiting
Indian Trial of Tranexamic Acid in Spontaneous Intracerebral Haemorrhage[NCT05836831]Phase 43,400 participants (Anticipated)Interventional2022-08-30Recruiting
STOP-AUST: The Spot Sign and Tranexamic Acid On Preventing ICH Growth - AUStralasia Trial.[NCT01702636]Phase 2100 participants (Actual)Interventional2012-12-31Completed
Benefits on Post-operative Pain of Intravenous, Intraoperative, Tranexamic Acid Injection During Arthroscopic Shoulder Surgery.[NCT05302986]Phase 3220 participants (Anticipated)Interventional2023-02-24Recruiting
Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma[NCT00307606]Phase 440 participants (Anticipated)Interventional2005-12-31Recruiting
Minimization of Bleeding Complications Through Utilization of Perioperative Tranexamic Acid in Breast Surgery: A Randomized Double-blinded Placebo-controlled Trial[NCT02615366]Phase 4800 participants (Anticipated)Interventional2016-02-29Not yet recruiting
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527]Phase 4100 participants (Anticipated)Interventional2019-10-07Recruiting
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
Randomized Placebo Controlled Study Using Tranexamic Acid in Revision Total Hip Arthroplasty[NCT00375440]0 participants (Actual)Interventional2005-02-28Withdrawn (stopped due to Study halted prematurely as investigator left the institution.)
Evaluation of Tranexamic Acid Prior to Surgery in the Geriatric Hip Fracture Population for the Reduction of Post-Operative Blood Transfusion[NCT03923959]Phase 3400 participants (Anticipated)Interventional2020-02-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Breasts With Development of Hematoma

The number of breasts with clinically significant hematoma (collection of blood under the skin) requiring either conservative management or operative washout was determined. (NCT04947514)
Timeframe: Up to 30 days

Interventionbreasts (Number)
Treatment Side (Right or Left)2
Placebo Side (Right or Left)1

Number of Participants Requiring a Blood Transfusion

The number of participants requiring blood transfusion was based on the postoperative decline in hematocrit level (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Number of Participants With Deep Vein Thrombosis/Venous Thromboembolism

Incidence of clinically significant deep vein thrombosis or pulmonary embolism detected on imaging (ultrasound or CT scan) (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Reviews

8 reviews available for tranexamic acid and Hematoma

ArticleYear
A Systematic Review and Meta-Analysis Evaluating the Impact of Tranexamic Acid Administration in Aesthetic Plastic Surgery.
    Aesthetic surgery journal, 2022, 04-12, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Female; Hematoma; Humans; Surgery, Plasti

2022
Tranexamic Acid for Adult Patients with Spontaneous Intracerebral Hemorrhage: A Systematic Review with Meta-analysis.
    CNS drugs, 2021, Volume: 35, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Cerebral Hemorrhage; Hematoma; Humans; Randomized Controlled Trials

2021
The role of tranexamic acid in reducing post-operative bleeding and seroma formation in breast surgery: A meta-analysis.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2023, Volume: 21, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Seroma; T

2023
Tranexamic Acid Use in Breast Surgery: A Systematic Review and Meta-Analysis.
    Plastic and reconstructive surgery, 2023, 05-01, Volume: 151, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Mastectom

2023
The Effects of Tranexamic Acid in Breast Surgery: A Systematic Review and Meta-Analysis.
    Plastic and reconstructive surgery, 2023, 12-01, Volume: 152, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Postopera

2023
Tranexamic Acid Inhibits Hematoma Expansion in Intracerebral Hemorrhage and Traumatic Brain Injury. Does Blood Pressure Play a Potential Role? A Meta-Analysis from Randmized Controlled Trials.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021, Volume: 30, Issue:1

    Topics: Antifibrinolytic Agents; Brain Hemorrhage, Traumatic; Cerebral Hemorrhage; Disease Progression; Hema

2021
Tranexamic acid in intracerebral hemorrhage: a meta-analysis.
    The International journal of neuroscience, 2023, Volume: 133, Issue:6

    Topics: Antifibrinolytic Agents; Cerebral Hemorrhage; Cohort Studies; Hematoma; Humans; Randomized Controlle

2023
Tranexamic acid can reduce blood loss in patients undergoing intertrochanteric fracture surgery: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hematoma; Hemoglobins; Hip Fractur

2019

Trials

20 trials available for tranexamic acid and Hematoma

ArticleYear
Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:2

    Topics: Antifibrinolytic Agents; Cerebral Hemorrhage; Clinical Trials, Phase II as Topic; Hematoma; Humans;

2022
Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial.
    JAMA neurology, 2022, 05-01, Volume: 79, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Cerebral Hemorrhage; Double-Blind Method; Female; Hematoma; Humans; I

2022
Intravenous Tranexamic Acid in Percutaneous Kidney Biopsy: A Randomized Controlled Trial.
    Nephron, 2023, Volume: 147, Issue:3-4

    Topics: Adult; Antifibrinolytic Agents; Biopsy; Double-Blind Method; Hematoma; Humans; Kidney; Tranexamic Ac

2023
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind Randomized Controlled Trial.
    Plastic and reconstructive surgery, 2023, 10-01, Volume: 152, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Breast Ne

2023
[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2023, Volume: 90, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hematoma; Humans; Postoperative Hemorrhage; Prospecti

2023
Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial.
    Stroke, 2023, Volume: 54, Issue:9

    Topics: Administration, Oral; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cerebral Hemorrhag

2023
Role of tranexamic acid-soaked gelatin sponge in minimizing rectus sheath hematoma after cesarean section in women treated with warfarin, a simple tool for high-risk cases, a randomized controlled trial.
    European journal of medical research, 2023, Oct-20, Volume: 28, Issue:1

    Topics: Anticoagulants; Cesarean Section; Female; Gelatin; Hematoma; Heparin; Heparin, Low-Molecular-Weight;

2023
Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial.
    Translational stroke research, 2021, Volume: 12, Issue:2

    Topics: Aged; Cerebral Hemorrhage; Hematoma; Humans; Logistic Models; Male; Tranexamic Acid

2021
Rationale and Design of a Randomized, Double-Blind Trial Evaluating the Efficacy of Tranexamic Acid on Hematoma Expansion and Peri-hematomal Edema in Patients with Spontaneous Intracerebral Hemorrhage within 4.5 h after Symptom Onset: The THE-ICH Trial Pr
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:10

    Topics: Antifibrinolytic Agents; Brain Edema; Cerebral Hemorrhage; China; Disease Progression; Double-Blind

2020
Effect of Intravenous Tranexamic Acid on Intracerebral Brain Hemorrhage in Traumatic Brain Injury.
    Turkish neurosurgery, 2021, Volume: 31, Issue:2

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Antifibrinolytic Agents; Brain Injuries, Traum

2021
Tranexamic acid for acute intracerebral haemorrhage growth based on imaging assessment (TRAIGE): a multicentre, randomised, placebo-controlled trial.
    Stroke and vascular neurology, 2021, Volume: 6, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Cerebral Hemorrhage; Female; Hematoma; Humans; Male; Middle Ag

2021
Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign.
    Stroke, 2021, Volume: 52, Issue:8

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Cerebral Angiography; Cerebral Hemorrhage; Compute

2021
Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial.
    BMC research notes, 2018, Jun-13, Volume: 11, Issue:1

    Topics: Antifibrinolytic Agents; Cerebral Hemorrhage; Data Interpretation, Statistical; Disease Progression;

2018
The spot sign and tranexamic acid on preventing ICH growth--AUStralasia Trial (STOP-AUST): protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Australia; Cerebral Angiography; Cerebral Hemorrhage; Contrast

2014
The spot sign and tranexamic acid on preventing ICH growth--AUStralasia Trial (STOP-AUST): protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Australia; Cerebral Angiography; Cerebral Hemorrhage; Contrast

2014
The spot sign and tranexamic acid on preventing ICH growth--AUStralasia Trial (STOP-AUST): protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Australia; Cerebral Angiography; Cerebral Hemorrhage; Contrast

2014
The spot sign and tranexamic acid on preventing ICH growth--AUStralasia Trial (STOP-AUST): protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial.
    International journal of stroke : official journal of the International Stroke Society, 2014, Volume: 9, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Australia; Cerebral Angiography; Cerebral Hemorrhage; Contrast

2014
Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Aspirin; Bl

2016
The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2017
[Tranexamic acid reduces haematomas but not pain after total knee arthroplasty].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:1

    Topics: Aged; Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Female; Hematom

2011
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Perioperative and postoperative tranexamic acid reduces the local wound complication rate after surgery for breast cancer.
    The British journal of surgery, 1994, Volume: 81, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Contusions; Double-Blind Me

1994
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Double-Blind Metho

2000

Other Studies

36 other studies available for tranexamic acid and Hematoma

ArticleYear
Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2022, 01-01, Volume: 149, Issue:1

    Topics: Antifibrinolytic Agents; Hematoma; Humans; Mammaplasty; Thromboembolism; Tranexamic Acid

2022
Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty.
    Aesthetic surgery journal, 2022, 05-18, Volume: 42, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hematoma; Humans

2022
Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients.
    Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Frail Elderly;

2022
Commentary on: Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty.
    Aesthetic surgery journal, 2022, 05-18, Volume: 42, Issue:6

    Topics: Female; Hematoma; Humans; Mammaplasty; Seroma; Tranexamic Acid

2022
Thoughts on: Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty.
    Aesthetic surgery journal, 2022, 12-14, Volume: 42, Issue:12

    Topics: Female; Hematoma; Humans; Mammaplasty; Seroma; Tranexamic Acid

2022
A Stepwise Haemostasis Intraoperative Protocol Driven Reduction of Haematoma Rate Following Symptomatic Carotidendarterectomy.
    Vascular and endovascular surgery, 2023, Volume: 57, Issue:2

    Topics: Carotid Stenosis; Endarterectomy, Carotid; Hematoma; Hemostasis; Humans; Protamines; Risk Factors; S

2023
The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates.
    Annals of plastic surgery, 2023, 06-01, Volume: 90, Issue:6S Suppl 4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hematoma; Humans; Mammaplasty; Retrospective

2023
Topical tranexamic acid reduces postoperative hematomas in reduction mammaplasties.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2023, Volume: 83

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Cohort Stu

2023
Efficacy of local infiltration of tranexamic acid in subcutaneous surgery: A protocol from a single medical center.
    Medicine, 2023, Sep-01, Volume: 102, Issue:35

    Topics: Fibrinolytic Agents; Hematoma; Humans; Postoperative Complications; Retrospective Studies; Surgeons;

2023
Factor XIII deficiency leading to preseptal haematoma post-strabismus surgery.
    BMJ case reports, 2019, Nov-13, Volume: 12, Issue:11

    Topics: Antifibrinolytic Agents; Child; Exotropia; Eyelid Diseases; Factor XIII Deficiency; Female; Hematoma

2019
Noncontrast Computed Tomography Signs as Predictors of Hematoma Expansion, Clinical Outcome, and Response to Tranexamic Acid in Acute Intracerebral Hemorrhage.
    Stroke, 2020, Volume: 51, Issue:1

    Topics: Aged; Cerebral Hemorrhage; Cohort Studies; Disease Progression; Female; Hematoma; Humans; Logistic M

2020
    BMJ case reports, 2020, May-04, Volume: 13, Issue:5

    Topics: Aged, 80 and over; Airway Obstruction; Antifibrinolytic Agents; Cyclophosphamide; Glucocorticoids; H

2020
Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Breast; Breast Implants; Breast Neoplasms; Dose-Response Relationshi

2020
Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Breast; Breast Implants; Breast Neoplasms; Dose-Response Relationshi

2020
Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Breast; Breast Implants; Breast Neoplasms; Dose-Response Relationshi

2020
Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Breast; Breast Implants; Breast Neoplasms; Dose-Response Relationshi

2020
Discussion: Intravenous Tranexamic Acid in Implant-Based Breast Reconstruction Safely Reduces Hematoma without Thromboembolic Events.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Antifibrinolytic Agents; Hematoma; Humans; Mammaplasty; Thromboembolism; Tranexamic Acid

2020
Improved platelet counts during prolonged tranexamic therapy for Quebec platelet disorder implicate the underlying fibrinolytic defect as the cause of lower platelet counts.
    International journal of laboratory hematology, 2020, Volume: 42, Issue:6

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Platelets; Factor V Deficiency; Fibrinol

2020
Hockey: a pain in the butt! Isolated superior gluteal artery rupture following blunt pelvic trauma - an unusual case.
    Annals of the Royal College of Surgeons of England, 2021, Volume: 103, Issue:3

    Topics: Aneurysm, False; Antifibrinolytic Agents; Buttocks; Computed Tomography Angiography; Embolization, T

2021
Primary hyperfibrinolysis as the presenting sign of prostate cancer: A case report.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:9

    Topics: Adenocarcinoma; Antifibrinolytic Agents; Biomarkers; Blood Coagulation Disorders; Blood Coagulation

2016
Pre-hospital care in stroke: A technological revolution.
    International journal of stroke : official journal of the International Stroke Society, 2018, Volume: 13, Issue:6

    Topics: Ambulances; Databases, Factual; Emergency Medical Services; Factor VIIa; Health Information Exchange

2018
Examining the use of intraoperative tranexamic acid in oncoplastic breast surgery.
    The breast journal, 2019, Volume: 25, Issue:5

    Topics: Antifibrinolytic Agents; Breast Neoplasms; Female; Hematoma; Humans; Mammaplasty; Mastectomy; Retros

2019
Tranexamic acid decreases risk of haematomas but not pain after hip arthroplasty.
    Orthopaedics & traumatology, surgery & research : OTSR, 2013, Volume: 99, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss

2013
Utility of thromboelastography in managing acquired Factor VIII inhibitor associated massive haemorrhage.
    Anaesthesia and intensive care, 2013, Volume: 41, Issue:6

    Topics: Antifibrinolytic Agents; Blood Coagulation Factors; Blood Transfusion; Endometrial Neoplasms; Factor

2013
Bleeding complications during cardiac electronic device implantation in patients receiving antithrombotic therapy: is there any value of local tranexamic acid?
    BMC cardiovascular disorders, 2016, Apr-22, Volume: 16

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Chi-Square Distributio

2016
Orbital subperiosteal hematoma after thrombolysis and anticoagulation for acute myocardial infarction.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2009, Volume: 29, Issue:3

    Topics: Accidental Falls; Acute Disease; Adult; Anticoagulants; Antifibrinolytic Agents; Craniocerebral Trau

2009
Comparative effectiveness of hemostatic therapy in experimental warfarin-associated intracerebral hemorrhage.
    Stroke, 2011, Volume: 42, Issue:1

    Topics: Animals; Anticoagulants; Blood Coagulation Factors; Cerebral Hemorrhage; Collagenases; Disease Model

2011
Giant abdominopelvic haematoma arising from ovulation in a Glanzmann's thrombasthenia patient with platelet refractoriness: treatment with surgery and intra-abdominal tranexamic acid.
    Acta haematologica, 2012, Volume: 128, Issue:3

    Topics: Adult; Corpus Luteum; Female; Hematoma; Humans; Ovarian Cysts; Ovulation; Rupture, Spontaneous; Thro

2012
Combination therapy of DDAVP and conjugated estrogens for a recurrent large subcutaneous hematoma in Ehlers-Danlos syndrome.
    American journal of hematology, 2003, Volume: 72, Issue:1

    Topics: Adrenochrome; Adult; Blood Transfusion; Combined Modality Therapy; Deamino Arginine Vasopressin; Dru

2003
Rapid administration of antifibrinolytics and strict blood pressure control for intracerebral hemorrhage.
    Neurosurgery, 2005, Volume: 57, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Blood Pressure; Case-Control Studies; Cerebral Hemo

2005
The use of topical crushed tranexamic acid tablets to control bleeding after dental surgery and from skin ulcers in haemophilia.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2007, Volume: 13, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Antifibrinolytic Agents; Dental Care for Chronically Ill

2007
Bleeding tendency caused by the deposit of amyloid substance in the perivascular region.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:11

    Topics: Adrenochrome; Amyloid; Amyloidosis; Blood Vessels; Female; Hematoma; Hemostatics; Humans; Middle Age

1993
Operative treatment of intramedullary hematoma associated with congenital deficiency of alpha 2-plasmin inhibitor, A report of three cases.
    The Journal of bone and joint surgery. American volume, 1996, Volume: 78, Issue:9

    Topics: Adolescent; alpha-2-Antiplasmin; Antifibrinolytic Agents; Bone Marrow Diseases; Child; Curettage; Du

1996
Severe hemorrhage after implant surgery.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1999, Volume: 87, Issue:1

    Topics: Adult; Airway Obstruction; Antifibrinolytic Agents; Dental Implantation, Endosseous; Hematoma; Human

1999
Treatment of subdural and intracerebral haematomas in a haemodialysis patient with tranexamic acid.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Hematoma; Hematoma, Subdural; Humans; Intracranial Hemorrhages; Male;

2000
An unusual cause of bleeding.
    Lancet (London, England), 2001, Oct-27, Volume: 358, Issue:9291

    Topics: Adult; Amyloidosis; Antifibrinolytic Agents; Female; Hematoma; Humans; Tranexamic Acid

2001
Intramedullary multiple hematomas in siblings with congenital alpha-2-plasmin inhibitor deficiency: orthopedic surgery with protection by tranexamic acid.
    Haemostasis, 1991, Volume: 21, Issue:5

    Topics: Adolescent; alpha-2-Antiplasmin; Blood Loss, Surgical; Bone Diseases; Child; Female; Femur; Hematoma

1991
Excessive fibrinolysis in suspected amyloidosis: demonstration of plasmin-alpha 2-plasmin inhibitor complex and von Willebrand factor fragment in plasma.
    American journal of hematology, 1986, Volume: 23, Issue:2

    Topics: alpha-2-Antiplasmin; Amyloidosis; Antifibrinolytic Agents; Fibrin Fibrinogen Degradation Products; F

1986
Oral nimodipine reduces prostaglandin and thromboxane production by arteries chronically exposed to a periarterial haematoma and the antifibrinolytic agent tranexamic acid.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Carotid Arteries; Cyclohexanecarboxylic Acids; Dinoprost; Din

1987