Page last updated: 2024-11-05

tranexamic acid and Hematoma, Subdural, Chronic

tranexamic acid has been researched along with Hematoma, Subdural, Chronic in 16 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Hematoma, Subdural, Chronic: Accumulation of blood in the SUBDURAL SPACE with delayed onset of neurological symptoms. Symptoms may include loss of consciousness, severe HEADACHE, and deteriorating mental status.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid (TXA) has been hypothesized as an oral agent to avoid CSDH progression and/or recurrence."3.30Effect of postoperative tranexamic acid on recurrence rate and complications in chronic subdural hematomas patients: preliminary results of a randomized controlled clinical trial. ( de Freitas, PVV; de Oliveira, MF; de Paula, MVCT; Melo, MM; Pahl, FH; Ribeiro, BDC; Rotta, JM, 2023)
"A total of 297 patients with chronic subdural hematoma underwent initial burr hole surgery at our hospital from April 2014 to March 2018."2.94Prospective Study on the Efficacy of Orally Administered Tranexamic Acid and Goreisan for the Prevention of Recurrence After Chronic Subdural Hematoma Burr Hole Surgery. ( Natori, Y; Yamada, T, 2020)
" Secondary endpoints were comparison of post-operative volumes between the treatment arms and safety evaluation of the dosing regime."2.94An open label randomized trial to assess the efficacy of tranexamic acid in reducing post-operative recurrence of chronic subdural haemorrhage. ( Khong, WXL; King, NKK; Ng, WH; Ong, JCL; Qiu, L; Saffari, SE; See, AA; Wan, KR, 2020)
" All patients were given Txa in the dosage of 750 mg/day in divided doses."1.56The Outcome of Medical Management of Chronic Subdural Hematoma with Tranexamic Acid - A Prospective Observational Study. ( Asher, P; Kutty, RK; Leela, SK; Peethambaran, A; Prabhakar, RB; Sivanandapanicker, JL; Sreemathyamma, SB, 2020)
"BACKGROUND Chronic subdural hematoma (CSDH) is a common neurosurgical condition that is treated using a cranial burr hole evacuation procedure, but recurrence is common."1.46A Case of Tranexamic Acid as Adjunctive Treatment for Chronic Subdural Hematoma with Multiple Recurrences. ( Anker-Møller, T; Hvas, AM; Mikkelsen, R; Sunde, N, 2017)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (25.00)24.3611
2020's12 (75.00)2.80

Authors

AuthorsStudies
Immenga, S2
Lodewijkx, R2
Roos, YBWEM1
Middeldorp, S1
Majoie, CBLM1
Willems, HC1
Vandertop, WP2
Verbaan, D2
Shibahashi, K1
Ohbe, H1
Yasunaga, H1
de Paula, MVCT1
Ribeiro, BDC1
Melo, MM1
de Freitas, PVV1
Pahl, FH1
de Oliveira, MF1
Rotta, JM1
Kumar, A1
Arsal, SA1
Shafique, MA1
Yamada, T1
Natori, Y1
Scerrati, A1
Visani, J1
Ricciardi, L1
Dones, F1
Rustemi, O1
Cavallo, MA1
De Bonis, P1
Kutty, RK2
Leela, SK1
Sreemathyamma, SB1
Sivanandapanicker, JL1
Asher, P1
Peethambaran, A1
Prabhakar, RB1
Suresh, V1
Sharma, S1
Wan, KR1
Qiu, L1
Saffari, SE1
Khong, WXL1
Ong, JCL1
See, AA1
Ng, WH1
King, NKK1
Panda, PK1
Sharawat, IK1
van den Berg, R1
Post, R1
Westerink, LG1
Nabuurs, RJA1
Can, A1
Mikkelsen, R1
Anker-Møller, T1
Hvas, AM1
Sunde, N1
Kageyama, H1
Toyooka, T1
Tsuzuki, N1
Oka, K1
Iorio-Morin, C1
Blanchard, J1
Richer, M1
Mathieu, D1
Wakabayashi, Y1
Yamashita, M1
Asano, T1
Yamada, A1
Kenai, H1
Kondoh, Y1
Hori, Y1
Nagatomi, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma. A Double-blind, Placebo-controlled, Multicentre, Randomized Controlled Clinical Trial[NCT03582293]Phase 3140 participants (Anticipated)Interventional2018-06-19Recruiting
TRACE STUDY: A Randomized Controlled Trial Using Tranexamic Acid in the Treatment of Subdural Hematoma[NCT05713630]Phase 3130 participants (Anticipated)Interventional2024-03-31Not yet recruiting
Tranexamic Acid in Chronic Subdural Hematomas[NCT02568124]Phase 2/Phase 3130 participants (Anticipated)Interventional2015-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tranexamic acid and Hematoma, Subdural, Chronic

ArticleYear
To drill or not to drill, that is the question: nonsurgical treatment of chronic subdural hematoma in the elderly. A systematic review.
    Neurosurgical focus, 2020, Volume: 49, Issue:4

    Topics: Aged; Embolization, Therapeutic; Hematoma, Subdural, Chronic; Humans; Meningeal Arteries; Tranexamic

2020

Trials

6 trials available for tranexamic acid and Hematoma, Subdural, Chronic

ArticleYear
Tranexamic acid to prevent operation in chronic subdural haematoma (TORCH): study protocol for a randomised placebo-controlled clinical trial.
    Trials, 2022, Jan-18, Volume: 23, Issue:1

    Topics: Activities of Daily Living; Aged; Clinical Trials, Phase III as Topic; Hematoma, Subdural, Chronic;

2022
Tranexamic acid to prevent operation in chronic subdural haematoma (TORCH): study protocol for a randomised placebo-controlled clinical trial.
    Trials, 2022, Jan-18, Volume: 23, Issue:1

    Topics: Activities of Daily Living; Aged; Clinical Trials, Phase III as Topic; Hematoma, Subdural, Chronic;

2022
Tranexamic acid to prevent operation in chronic subdural haematoma (TORCH): study protocol for a randomised placebo-controlled clinical trial.
    Trials, 2022, Jan-18, Volume: 23, Issue:1

    Topics: Activities of Daily Living; Aged; Clinical Trials, Phase III as Topic; Hematoma, Subdural, Chronic;

2022
Tranexamic acid to prevent operation in chronic subdural haematoma (TORCH): study protocol for a randomised placebo-controlled clinical trial.
    Trials, 2022, Jan-18, Volume: 23, Issue:1

    Topics: Activities of Daily Living; Aged; Clinical Trials, Phase III as Topic; Hematoma, Subdural, Chronic;

2022
Effect of postoperative tranexamic acid on recurrence rate and complications in chronic subdural hematomas patients: preliminary results of a randomized controlled clinical trial.
    Neurosurgical review, 2023, Apr-18, Volume: 46, Issue:1

    Topics: Aged; Drainage; Hematoma, Subdural, Chronic; Humans; Postoperative Complications; Postoperative Peri

2023
Letter to the editor: Effect of postoperative tranexamic acid on recurrence rate and complications in chronic subdural hematomas patients: preliminary results of a randomized controlled clinical trial.
    Neurosurgical review, 2023, 09-07, Volume: 46, Issue:1

    Topics: Hematoma, Subdural, Chronic; Humans; Tranexamic Acid

2023
Prospective Study on the Efficacy of Orally Administered Tranexamic Acid and Goreisan for the Prevention of Recurrence After Chronic Subdural Hematoma Burr Hole Surgery.
    World neurosurgery, 2020, Volume: 134

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Drugs, Chinese Herbal; Female; Follow-Up Studie

2020
An open label randomized trial to assess the efficacy of tranexamic acid in reducing post-operative recurrence of chronic subdural haemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 82, Issue:Pt A

    Topics: Aged; Antifibrinolytic Agents; Female; Hematoma, Subdural, Chronic; Humans; Male; Neurosurgical Proc

2020
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016
Tranexamic Acid in Chronic Subdural Hematomas (TRACS): study protocol for a randomized controlled trial.
    Trials, 2016, May-05, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Clinical Protocols; Cognition; Double-Blind Method; Hematoma, Subdural, Chr

2016

Other Studies

9 other studies available for tranexamic acid and Hematoma, Subdural, Chronic

ArticleYear
Adjuvant oral tranexamic acid and reoperation after burr hole surgery in patients with chronic subdural hematoma: propensity score-matched analysis using a nationwide inpatient database.
    Journal of neurosurgery, 2023, 02-01, Volume: 138, Issue:2

    Topics: Drainage; Hematoma, Subdural, Chronic; Humans; Inpatients; Propensity Score; Recurrence; Reoperation

2023
The Outcome of Medical Management of Chronic Subdural Hematoma with Tranexamic Acid - A Prospective Observational Study.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Conservative Treatment; Female; Hematoma, S

2020
Medical Management of Chronic Subdural Hematoma with Tranexamic Acid.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021, Volume: 30, Issue:2

    Topics: Antifibrinolytic Agents; Hematoma, Subdural, Chronic; Humans; Tranexamic Acid; Treatment Outcome

2021
Reply to Letter to Editor.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021, Volume: 30, Issue:2

    Topics: Hematoma, Subdural, Chronic; Humans; Tranexamic Acid

2021
Preventive role of tranexamic acid in post-operative recurrence of chronic subdural haemorrhage: Do we have sufficient evidence?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 89

    Topics: Antifibrinolytic Agents; Hematoma, Subdural, Chronic; Humans; Postoperative Period; Recurrence; Tran

2021
Tranexamic acid for chronic subdural hematoma.
    British journal of neurosurgery, 2021, Volume: 35, Issue:5

    Topics: Drainage; Hematoma, Subdural, Chronic; Humans; Tranexamic Acid; Treatment Outcome; Trephining

2021
A Case of Tranexamic Acid as Adjunctive Treatment for Chronic Subdural Hematoma with Multiple Recurrences.
    The American journal of case reports, 2017, Sep-15, Volume: 18

    Topics: Antifibrinolytic Agents; Combined Modality Therapy; Craniotomy; Hematoma, Subdural, Chronic; Humans;

2017
Nonsurgical treatment of chronic subdural hematoma with tranexamic acid.
    Journal of neurosurgery, 2013, Volume: 119, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Brain; Combined Modality Therapy; Female; Hematoma

2013
Nonsurgical treatment of chronic subdural hematoma with tranexamic acid.
    Journal of neurosurgery, 2013, Volume: 119, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Brain; Combined Modality Therapy; Female; Hematoma

2013
Nonsurgical treatment of chronic subdural hematoma with tranexamic acid.
    Journal of neurosurgery, 2013, Volume: 119, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Brain; Combined Modality Therapy; Female; Hematoma

2013
Nonsurgical treatment of chronic subdural hematoma with tranexamic acid.
    Journal of neurosurgery, 2013, Volume: 119, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Brain; Combined Modality Therapy; Female; Hematoma

2013
[Effect of Gorei-san with tranexamic acid for preventing recurrence of chronic subdural hematoma].
    No shinkei geka. Neurological surgery, 2012, Volume: 40, Issue:11

    Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Hematoma, Subdura

2012