Page last updated: 2024-11-05

tranexamic acid and Hematemesis

tranexamic acid has been researched along with Hematemesis in 6 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Hematemesis: Vomiting of blood that is either fresh bright red, or older coffee-ground in character. It generally indicates bleeding of the UPPER GASTROINTESTINAL TRACT.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both."5.05Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morgan, A1
Jeffrey-Smith, A1
Barer, D1
Ogilvie, A1
Henry, D1
Dronfield, M1
Coggon, D1
French, S1
Ellis, S1
Atkinson, M1
Langman, M2
Katschinski, B1
Logan, R1
Davies, J1
Faulkner, G1
Pearson, J1
Ostberg, HO1
Ulfberg, J1
Wennerholm, M1
Zellner, K1
Langman, MJ2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of High Dose Infusion and Low Dose Bolus Intravenous Omeprazole for Treatment of Bleeding Ulcer With Adherent Clot[NCT02536989]Phase 440 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for tranexamic acid and Hematemesis

ArticleYear
BET 1: should tranexamic acid be given to patients who are having an upper gastrointestinal bleed?
    Emergency medicine journal : EMJ, 2012, Volume: 29, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Emergency Service, Hospital; Evidence-Based Emergency Medicine; Hema

2012
Drug treatment of haematemesis and melaena.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 137

    Topics: Hematemesis; Histamine H2 Antagonists; Humans; Melena; Somatostatin; Tranexamic Acid

1987

Trials

3 trials available for tranexamic acid and Hematemesis

ArticleYear
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
    The New England journal of medicine, 1983, Jun-30, Volume: 308, Issue:26

    Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind

1983
Prognostic factors in upper gastrointestinal bleeding.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Duodenal Ulcer; Female

1994
Drug treatment for haematemesis and melaena.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 2

    Topics: Clinical Trials as Topic; Duodenal Ulcer; Hematemesis; Histamine H2 Antagonists; Humans; Laser Thera

1986

Other Studies

1 other study available for tranexamic acid and Hematemesis

ArticleYear
Acute gastrointestinal haemorrhage. Experience with early panendoscopy and tranexamic acid in a rural hospital.
    Acta chirurgica Scandinavica, 1977, Volume: 143, Issue:7-8

    Topics: Acute Disease; Adult; Aged; Cyclohexanecarboxylic Acids; Endoscopy; Gastrointestinal Hemorrhage; Hem

1977