tranexamic acid has been researched along with Hemarthrosis in 28 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Hemarthrosis: Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation." | 9.41 | Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021) |
| "To evaluate the effects of administering tranexamic acid (TXA) to minimize knee joint hemarthrosis and associated pain." | 9.20 | Reducing Intra-articular Hemarthrosis After Arthroscopic Anterior Cruciate Ligament Reconstruction by the Administration of Intravenous Tranexamic Acid: A Prospective, Randomized Controlled Trial. ( Karaaslan, F; Karaoğlu, S; Yurdakul, E, 2015) |
| "To systematically review the literature to compare the efficacy and safety of tranexamic acid (TXA) as a means to minimize hemarthrosis-related complications after arthroscopic procedures of the knee, hip, and shoulder." | 9.12 | Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies. ( Belk, JW; Dragoo, JL; Houck, DA; McCarty, EC; Savoie, FH; Thon, SG, 2021) |
| "Tranexamic acid (TXA) is an effective agent used for reducing perioperative blood loss and decreasing the potential for postoperative hemarthrosis." | 7.88 | Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty. ( Boyle, KK; Nodzo, SR; Pavlesen, S; Ritter, C, 2018) |
| "The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation." | 5.41 | Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021) |
| "To systematically review the literature to compare the efficacy and safety of tranexamic acid (TXA) as a means to minimize hemarthrosis-related complications after arthroscopic procedures of the knee, hip, and shoulder." | 5.12 | Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies. ( Belk, JW; Dragoo, JL; Houck, DA; McCarty, EC; Savoie, FH; Thon, SG, 2021) |
| "To analyze the available literature on hemarthrosis, pain, functional outcomes, and complications after administration of tranexamic acid in ACL reconstruction procedures." | 5.12 | Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. ( Ciccotti, MG; Gonzalez, TA; Hammoud, S; Johns, WL; Patel, NK; Walley, KC, 2021) |
| "Tranexamic acid (TXA) is an antifibrinolytic that lowers the risk of hemarthrosis-related surgical complications and has been extensively studied in orthopaedic trauma surgery, primary and revision total joint replacement, open shoulder reconstruction, and spine surgery." | 4.02 | Editorial Commentary: The Benefits of Tranexamic Acid May Outweigh Risks in Arthroscopy and Sports Medicine. ( Alaia, MJ; Gipsman, AM, 2021) |
| "Tranexamic acid (TXA) is an effective agent used for reducing perioperative blood loss and decreasing the potential for postoperative hemarthrosis." | 3.88 | Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty. ( Boyle, KK; Nodzo, SR; Pavlesen, S; Ritter, C, 2018) |
| "The bleeding was effectively controlled within 1 to 48 h in five of nine bleeding episodes." | 2.69 | Controlling acute bleeding episodes with recombinant factor VIIa in haemophiliacs with inhibitor: continuous infusion and bolus injection. ( Angchaisuksiri, P; Chuansumrit, A; Hathirat, P; Isarangkura, P; Jorgensen, LN; Sriudomporn, N; Tanpowpong, K, 2000) |
| "Haemophilia B is an inherited bleeding disorder associated with a deficiency of coagulation factor IX." | 2.43 | Haemophilia B: Christmas disease. ( Giangrande, P, 2005) |
| "However, hemarthrosis is the most common complication in arthroscopic surgery, which has potential adverse effects on postoperative rehabilitation." | 1.91 | Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study. ( Chen, G; Fu, W; Li, J; Li, Q; Tang, X; Xiong, Y; Yao, L; You, M, 2023) |
| "Approximately 50% of female carriers of hemophilia A have factor VIII (FVIII) levels below 0." | 1.56 | Hemophilia A in Females: Considerations for Clinical Management. ( Boukouvala, A; Bryant, P; McDaniel, J; Nance, D, 2020) |
| "Tranexamic acid (TXA) has a high clinical value for the treatment of bleeding due to fibrinolysis." | 1.42 | Warfarin-related recurrent knee haemarthrosis treated with arterial embolisation and intra-articular injection of tranexamic acid. ( Kunugiza, Y; Mikami, K; Nakamura, Y; Suzuki, S, 2015) |
| "Glanzmann thrombasthenia (GT) is a rare bleeding syndrome, which is characterized by a lack of platelet aggregation." | 1.36 | Glanzmann thrombasthenia detected because of knee hemarthrosis: a case report. ( Ishiguro, N; Katsumi, A; Nishida, Y; Tsukushi, S; Urakawa, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 14 (50.00) | 24.3611 |
| 2020's | 12 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Goldstein, K | 1 |
| Jones, C | 1 |
| Kay, J | 1 |
| Shin, J | 1 |
| de Sa, D | 1 |
| Li, J | 2 |
| You, M | 1 |
| Yao, L | 1 |
| Fu, W | 1 |
| Li, Q | 1 |
| Chen, G | 1 |
| Tang, X | 1 |
| Xiong, Y | 1 |
| Hetsroni, I | 1 |
| Siegel, MG | 1 |
| Gobbi, RG | 1 |
| Giglio, PN | 1 |
| Helito, CP | 1 |
| Pécora, JR | 1 |
| Ma, HL | 2 |
| Bryant, P | 1 |
| Boukouvala, A | 1 |
| McDaniel, J | 1 |
| Nance, D | 1 |
| Hayward, CPM | 1 |
| Tasneem, S | 1 |
| Rivard, GE | 1 |
| Belk, JW | 1 |
| McCarty, EC | 1 |
| Houck, DA | 1 |
| Dragoo, JL | 1 |
| Savoie, FH | 1 |
| Thon, SG | 1 |
| Ma, R | 1 |
| Wu, M | 1 |
| Li, Y | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Yang, P | 1 |
| Wang, K | 1 |
| Fried, JW | 2 |
| Bloom, DA | 2 |
| Hurley, ET | 2 |
| Baron, SL | 2 |
| Popovic, J | 2 |
| Campbell, KA | 2 |
| Strauss, EJ | 2 |
| Jazrawi, LM | 2 |
| Alaia, MJ | 3 |
| Johns, WL | 1 |
| Walley, KC | 1 |
| Hammoud, S | 1 |
| Gonzalez, TA | 1 |
| Ciccotti, MG | 1 |
| Patel, NK | 1 |
| Gipsman, AM | 1 |
| Zhang, S | 1 |
| Dai, Y | 1 |
| Xiao, C | 1 |
| Alkhatib, N | 1 |
| AlNouri, M | 1 |
| Abdullah, ASA | 1 |
| Ahmad Alzobi, OZ | 1 |
| Alkaramany, E | 1 |
| Sasaki, E | 1 |
| Ishibashi, Y | 1 |
| Dorweiler, MA | 1 |
| Boin, MA | 1 |
| Froehle, AW | 1 |
| Lawless, MW | 1 |
| May, JH | 1 |
| Nodzo, SR | 1 |
| Pavlesen, S | 1 |
| Ritter, C | 1 |
| Boyle, KK | 1 |
| Felli, L | 1 |
| Revello, S | 1 |
| Burastero, G | 1 |
| Gatto, P | 1 |
| Carletti, A | 1 |
| Formica, M | 1 |
| Alessio-Mazzola, M | 1 |
| Chiang, ER | 1 |
| Chen, KH | 1 |
| Wang, ST | 1 |
| Chang, MC | 1 |
| Liu, CL | 1 |
| Chen, TH | 1 |
| Karaaslan, F | 3 |
| Kunugiza, Y | 1 |
| Nakamura, Y | 1 |
| Mikami, K | 1 |
| Suzuki, S | 1 |
| Karaoğlu, S | 2 |
| Yurdakul, E | 2 |
| Milankov, M | 1 |
| Savic, D | 1 |
| Urakawa, H | 1 |
| Nishida, Y | 1 |
| Tsukushi, S | 1 |
| Katsumi, A | 1 |
| Ishiguro, N | 1 |
| Giangrande, P | 1 |
| Chuansumrit, A | 1 |
| Isarangkura, P | 1 |
| Angchaisuksiri, P | 1 |
| Sriudomporn, N | 1 |
| Tanpowpong, K | 1 |
| Hathirat, P | 1 |
| Jorgensen, LN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of the Application of a New Pharmacological Protocol for Shoulder Arthroscopy in Beach Chair Position[NCT05397652] | Phase 4 | 104 participants (Actual) | Interventional | 2021-05-24 | Completed | ||
| Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-blind and Randomized Controlled Trial[NCT04025736] | 72 participants (Actual) | Interventional | 2017-06-07 | Completed | |||
| Does Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Arthroscopic Surgery Reduce Postoperative Haemarthrosis and Improve Functional Prognosis?[NCT04855877] | Phase 4 | 104 participants (Anticipated) | Interventional | 2021-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for tranexamic acid and Hemarthrosis
| Article | Year |
|---|---|
Tranexamic Acid Administration in Arthroscopic Surgery Is a Safe Adjunct to Decrease Postoperative Pain and Swelling: A Systematic Review and Meta-analysis.
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Blood Loss, Surgical; Female; Hemarth | 2022 |
Tranexamic Acid Use in Knee and Shoulder Arthroscopy Leads to Improved Outcomes and Fewer Hemarthrosis-Related Complications: A Systematic Review of Level I and II Studies.
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Hemarthrosis; Humans; Knee; Lysholm K | 2021 |
Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.
Topics: Adult; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Hemarthrosis; | 2021 |
Tranexamic Acid Use in Anterior Cruciate Ligament Reconstruction Decreases Bleeding Complications: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Female; Hemarthrosis; Humans; Male; Randomized Con | 2022 |
Haemophilia B: Christmas disease.
Topics: Antifibrinolytic Agents; Autoantibodies; Clinical Trials as Topic; Developing Countries; Factor IX; | 2005 |
6 trials available for tranexamic acid and Hemarthrosis
| Article | Year |
|---|---|
The comparative efficacies of intravenous administration and intra-articular injection of tranexamic acid during anterior cruciate ligament reconstruction for reducing postoperative hemarthrosis: a prospective randomized study.
Topics: Administration, Intravenous; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconst | 2021 |
Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial.
Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Autografts; Bone-Pat | 2021 |
Single Intravenous Administration of Tranexamic Acid in Anterior Cruciate Ligament Reconstruction to Reduce Postoperative Hemarthrosis and Increase Functional Outcomes in the Early Phase of Postoperative Rehabilitation: A Randomized Controlled Trial.
Topics: Adolescent; Adult; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; A | 2019 |
Intra-articular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Study.
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Antifibrinolytic Agents; Arthroscopy; Female; Hema | 2019 |
Reducing Intra-articular Hemarthrosis After Arthroscopic Anterior Cruciate Ligament Reconstruction by the Administration of Intravenous Tranexamic Acid: A Prospective, Randomized Controlled Trial.
Topics: Adolescent; Adult; Anterior Cruciate Ligament Reconstruction; Child; Double-Blind Method; Female; He | 2015 |
Reducing Intra-articular Hemarthrosis After Arthroscopic Anterior Cruciate Ligament Reconstruction by the Administration of Intravenous Tranexamic Acid: A Prospective, Randomized Controlled Trial.
Topics: Adolescent; Adult; Anterior Cruciate Ligament Reconstruction; Child; Double-Blind Method; Female; He | 2015 |
Reducing Intra-articular Hemarthrosis After Arthroscopic Anterior Cruciate Ligament Reconstruction by the Administration of Intravenous Tranexamic Acid: A Prospective, Randomized Controlled Trial.
Topics: Adolescent; Adult; Anterior Cruciate Ligament Reconstruction; Child; Double-Blind Method; Female; He | 2015 |
Reducing Intra-articular Hemarthrosis After Arthroscopic Anterior Cruciate Ligament Reconstruction by the Administration of Intravenous Tranexamic Acid: A Prospective, Randomized Controlled Trial.
Topics: Adolescent; Adult; Anterior Cruciate Ligament Reconstruction; Child; Double-Blind Method; Female; He | 2015 |
Controlling acute bleeding episodes with recombinant factor VIIa in haemophiliacs with inhibitor: continuous infusion and bolus injection.
Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Child, Preschool; Disease Management; Fact | 2000 |
17 other studies available for tranexamic acid and Hemarthrosis
| Article | Year |
|---|---|
Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study.
Topics: Administration, Topical; Antifibrinolytic Agents; Arthroscopy; Blood Loss, Surgical; Hemarthrosis; H | 2023 |
Tranexamic Acid During Anterior Cruciate Ligament Reconstruction Reduced Drained Blood Volume on Day 1 and Hemarthrosis Up to Day 15 but Did Not Improve Clinical Outcomes at 3 Months.
Topics: Administration, Intravenous; Anterior Cruciate Ligament Reconstruction; Blood Volume; Hemarthrosis; | 2019 |
The Dangers and Concerns of Intra-articular Tranexamic Acid.
Topics: Anterior Cruciate Ligament Reconstruction; Blood Loss, Surgical; Hemarthrosis; Humans; Injections, I | 2019 |
Regarding "Intra-articular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Study".
Topics: Anterior Cruciate Ligament Reconstruction; Hemarthrosis; Humans; Injections, Intra-Articular; Prospe | 2019 |
Author Reply to "The Dangers and Concerns of Intra-articular Tranexamic Acid" and "Regarding 'Intra-articular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction: A Prospective Randomiz
Topics: Anterior Cruciate Ligament Reconstruction; Hemarthrosis; Humans; Injections, Intra-Articular; Prospe | 2019 |
Hemophilia A in Females: Considerations for Clinical Management.
Topics: Adolescent; Aged; Chromosome Inversion; Deamino Arginine Vasopressin; Disease Management; Drug Subst | 2020 |
Improved platelet counts during prolonged tranexamic therapy for Quebec platelet disorder implicate the underlying fibrinolytic defect as the cause of lower platelet counts.
Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Platelets; Factor V Deficiency; Fibrinol | 2020 |
Editorial Commentary: The Benefits of Tranexamic Acid May Outweigh Risks in Arthroscopy and Sports Medicine.
Topics: Arthroscopy; Hemarthrosis; Humans; Shoulder; Sports Medicine; Tranexamic Acid | 2021 |
Regarding "Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial".
Topics: Anterior Cruciate Ligament Reconstruction; Autografts; Bone-Patellar Tendon-Bone Grafting; Double-Bl | 2021 |
Author Reply to "Regarding 'Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial'".
Topics: Anterior Cruciate Ligament Reconstruction; Autografts; Bone-Patellar Tendon-Bone Grafting; Double-Bl | 2021 |
Improved Early Postoperative Range of Motion in Total Knee Arthroplasty Using Tranexamic Acid: A Retrospective Analysis.
Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies | 2019 |
Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty.
Topics: Aged; Ankle Joint; Antifibrinolytic Agents; Arthroplasty, Replacement, Ankle; Blood Loss, Surgical; | 2018 |
Editorial Commentary: Tranexamic Acid: Okay, It Reduces the Bleeding, but Are We Sure Topical Use Is Not Harmful to the Cartilage?
Topics: Anterior Cruciate Ligament Reconstruction; Cartilage; Hemarthrosis; Humans; Injections, Intra-Articu | 2019 |
Warfarin-related recurrent knee haemarthrosis treated with arterial embolisation and intra-articular injection of tranexamic acid.
Topics: Anticoagulants; Antifibrinolytic Agents; Embolization, Therapeutic; Female; Hemarthrosis; Humans; In | 2015 |
Reducing Intra-articular Hemarthrosis After Arthroscopic ACL Reconstruction: Letter to the Editor.
Topics: Anterior Cruciate Ligament Reconstruction; Female; Hemarthrosis; Humans; Knee Joint; Male; Tranexami | 2016 |
Reducing Intra-articular Hemarthrosis After Arthroscopic ACL Reconstruction: Response.
Topics: Anterior Cruciate Ligament Reconstruction; Female; Hemarthrosis; Humans; Knee Joint; Male; Tranexami | 2016 |
Glanzmann thrombasthenia detected because of knee hemarthrosis: a case report.
Topics: Antifibrinolytic Agents; Arthralgia; Bleeding Time; Child; Diagnosis, Differential; Hemarthrosis; Hu | 2010 |