tranexamic acid has been researched along with Gastrointestinal Hemorrhage in 98 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Excerpt | Relevance | Reference |
---|---|---|
"Tranexamic acid (TXA) is an antifibrinolytic agent used to control bleeding in different circumstances." | 6.94 | A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage. ( Doğan, NÖ; Karadaş, A; Pekdemir, M; Pinar, SG; Yaka, E; Yeşil, O; Yilmaz, S, 2020) |
"The current therapeutic strategy for disseminated intravascular coagulation (DIC) is limited to control of the underlying disease, and methods for the effective management of DIC have not been established." | 5.34 | Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis. ( Asada, N; Asakura, H; Koseki, M; Matsue, K; Takeuchi, M; Uryu, H, 2007) |
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)." | 5.30 | Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998) |
"Tranexamic acid appears to be a reasonable adjunct for the emergency medicine clinician to consider in the management of many hemorrhagic conditions and angiotensin converting enzyme inhibitor-induced angioedema." | 5.22 | Tranexamic acid - A narrative review for the emergency medicine clinician. ( Santiago, R; Wang, K, 2022) |
"We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both." | 5.05 | Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983) |
"The effect or oral tranexamic acid on massive upper gastrointestinal hemorrhage was evaluated in a randomized double-blind study." | 5.05 | Local inhibition of the fibrinolytic system in patients with massive upper gastrointestinal hemorrhage. ( Bergqvist, D; Dahlgren, S; Hessman, Y, 1980) |
"To report a case of toxic epidermal necrolysis (TEN) induced by orally administered tranexamic acid in a patient with liver cirrhosis and acute rectal bleeding." | 3.79 | Tranexamic acid-induced toxic epidermal necrolysis. ( Aguado Gil, L; Idoate Gastearena, MA; Marques Martin, L; Pretel Irazabal, M, 2013) |
" prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin." | 3.67 | Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985) |
"Tranexamic acid (TXA) is a common haemorrhage control agent in both emergency department (ED) settings and intra-operatively." | 3.01 | Tranexamic acid in emergency medicine. An overview of reviews. ( Dhingra, P; Lang, E; Yeung, M, 2023) |
"Tranexamic acid (TXA) is an antifibrinolytic agent used to control bleeding in different circumstances." | 2.94 | A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage. ( Doğan, NÖ; Karadaş, A; Pekdemir, M; Pinar, SG; Yaka, E; Yeşil, O; Yilmaz, S, 2020) |
"Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98)." | 2.94 | Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. ( , 2020) |
"Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions." | 2.87 | Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial. ( Bendinelli, C; Carroll, R; Draganic, BD; Murray, D; Pockney, PG; Smith, SR, 2018) |
"Studies were analyzed as high-dose IV tranexamic acid versus all other dosing strategies for tranexamic acid using fixed-effects models." | 2.82 | Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis. ( Antonelli, M; Dionne, JC; Hunt, BJ; Oczkowski, SJW; Raasveld, SJ; Vlaar, APJ; Wijnberge, M, 2022) |
"Tranexamic acid has been shown to reduce the need for blood transfusion in surgical patients and to reduce mortality in bleeding trauma patients, with no apparent increase in thromboembolic events." | 2.79 | HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial. ( Coats, T; Edwards, P; Gilmore, I; Jairath, V; Ker, K; Manno, D; Roberts, I; Shakur, H; Stanworth, S; Veitch, A, 2014) |
" In 16 episodes of bleeding TXA was used (in a dosage of 20 mg intravenously, followed for the next 4 weeks by 10 mg/kg/48 h orally), whereas in 20 other cases of bleeding, TXA was not used." | 2.71 | Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients. ( Lavre, J; Sabovic, M; Vujkovac, B, 2003) |
"Treatment with tranexamic acid was associated with a 20-30% reduction in the rate of rebleeding, a 30-40% reduction (95% confidence interval 10% to 60%) in mortality." | 2.66 | Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage. ( Henry, DA; O'Connell, DL, 1989) |
" Therefore, thromboembolic risk and tranexamic acid dosage should be carefully evaluated." | 2.53 | [Tranexamic acid for upper gastrointestinal bleeding]. ( Fenger-Eriksen, C; Jessing, TD, 2016) |
"The current therapeutic strategy for disseminated intravascular coagulation (DIC) is limited to control of the underlying disease, and methods for the effective management of DIC have not been established." | 1.34 | Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis. ( Asada, N; Asakura, H; Koseki, M; Matsue, K; Takeuchi, M; Uryu, H, 2007) |
"A patient with von Willebrand's disease had recurrent gastrointestinal bleeding from angiodysplasia, with inadequate response to von Willebrand factor substitution, medical and endoscopic treatment, and resection of affected bowel." | 1.31 | Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa. ( Meijer, K; Peters, FT; van der Meer, J, 2001) |
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)." | 1.30 | Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (21.43) | 18.7374 |
1990's | 7 (7.14) | 18.2507 |
2000's | 12 (12.24) | 29.6817 |
2010's | 27 (27.55) | 24.3611 |
2020's | 31 (31.63) | 2.80 |
Authors | Studies |
---|---|
Roberts, I | 8 |
Shakur-Still, H | 3 |
Afolabi, A | 2 |
Akere, A | 1 |
Arribas, M | 3 |
Austin, E | 1 |
Bal, K | 1 |
Bazeer, N | 1 |
Beaumont, D | 2 |
Brenner, A | 2 |
Carrington, L | 1 |
Chaudhri, R | 2 |
Coats, T | 4 |
Gilmore, I | 4 |
Halligan, K | 1 |
Hussain, I | 1 |
Jairath, V | 4 |
Javaid, K | 2 |
Kayani, A | 2 |
Lisman, T | 1 |
Mansukhani, R | 2 |
Miners, A | 1 |
Mutti, M | 2 |
Nadeem, MA | 2 |
Pollok, R | 1 |
Prowse, D | 1 |
Simmons, J | 1 |
Stanworth, S | 3 |
Veitch, A | 4 |
Williams, J | 1 |
Dionne, JC | 1 |
Oczkowski, SJW | 1 |
Hunt, BJ | 1 |
Antonelli, M | 1 |
Wijnberge, M | 1 |
Raasveld, SJ | 1 |
Vlaar, APJ | 1 |
Fong, MW | 1 |
Morningstar-Kywi, N | 1 |
O'Connell, C | 1 |
Qureshi, U | 1 |
Han, EE | 1 |
Wang, K | 1 |
Santiago, R | 1 |
Tran, QK | 1 |
Tang, K | 1 |
Pourmand, A | 1 |
Tsai, HW | 2 |
Lee, PL | 4 |
Kang, YN | 5 |
Grocott, MPW | 2 |
Murphy, M | 2 |
Sayers, R | 2 |
Toh, CH | 2 |
Dhingra, P | 1 |
Yeung, M | 1 |
Lang, E | 1 |
Ker, K | 3 |
Fujimori, S | 1 |
Ochoco, GETD | 1 |
Enriquez, CAG | 1 |
Urgel, RJL | 1 |
Catibog, JS | 1 |
Karadaş, A | 1 |
Doğan, NÖ | 1 |
Pinar, SG | 1 |
Yeşil, O | 1 |
Pekdemir, M | 1 |
Yilmaz, S | 1 |
Yaka, E | 1 |
Stanworth, SJ | 2 |
Twum-Barimah, E | 1 |
Abdelgadir, I | 1 |
Gordon, M | 1 |
Akobeng, AK | 1 |
Perner, A | 1 |
Møller, MH | 1 |
Dorgalaleh, A | 1 |
Baghaipour, MR | 1 |
Tabibian, S | 1 |
Ghazizadeh, F | 1 |
Dabbagh, A | 1 |
Bahoush, G | 1 |
Jazebi, M | 1 |
Bahraini, M | 1 |
Fazeli, A | 1 |
Baghaipour, N | 1 |
Yousefi, F | 1 |
Roberts, LN | 1 |
Miyamoto, Y | 1 |
Ohbe, H | 1 |
Ishimaru, M | 1 |
Matsui, H | 1 |
Fushimi, K | 1 |
Yasunaga, H | 1 |
Gilbert, BW | 1 |
Rech, MA | 1 |
Yang, KS | 1 |
Hou, SK | 1 |
Chang, CC | 2 |
Horton, LC | 1 |
Feuerstein, JD | 1 |
Erasu, V | 1 |
Novak, A | 1 |
Kamal, F | 1 |
Khan, MA | 1 |
Lee-Smith, W | 1 |
Sharma, S | 1 |
Imam, Z | 1 |
Jowhar, D | 1 |
Petryna, E | 1 |
Marella, HK | 1 |
Aksionav, P | 1 |
Iqbal, U | 1 |
Tombazzi, C | 1 |
Howden, CW | 1 |
Suk, FM | 1 |
Al-Samkari, H | 1 |
Ho, YW | 1 |
Chang, CY | 1 |
Huang, HK | 1 |
Chen, YL | 1 |
Wu, MY | 1 |
Polsky, Z | 1 |
Damji, O | 1 |
Bond, C | 1 |
Ma, C | 1 |
Lin, YC | 1 |
Chen, CY | 1 |
Murata, M | 1 |
Bamba, S | 1 |
Takahashi, K | 1 |
Imaeda, H | 1 |
Nishida, A | 1 |
Inatomi, O | 1 |
Tsujikawa, T | 1 |
Kushima, R | 1 |
Sugimoto, M | 1 |
Andoh, A | 1 |
Stollings, JL | 1 |
Landsperger, JS | 1 |
Semler, MW | 1 |
Rice, TW | 1 |
Grooteman, KV | 1 |
van Geenen, EJM | 1 |
Drenth, JPH | 1 |
Smith, SR | 1 |
Murray, D | 1 |
Pockney, PG | 1 |
Bendinelli, C | 1 |
Draganic, BD | 1 |
Carroll, R | 1 |
Sepulveda, A | 1 |
Soriano, H | 1 |
Espino, A | 1 |
Heidet, M | 1 |
Amathieu, R | 1 |
Audureau, E | 1 |
Augusto, O | 1 |
Nicolazo de Barmon, V | 1 |
Rialland, A | 1 |
Schmitz, D | 1 |
Pierrang, F | 1 |
Marty, J | 1 |
Chollet-Xémard, C | 1 |
Thirion, O | 1 |
Jacob, L | 1 |
Altawil, Z | 1 |
Gendron, BJ | 1 |
Schechter-Perkins, EM | 1 |
Cotzias, E | 1 |
Rehman, SF | 1 |
Arsalani Zadeh, R | 1 |
Smith, D | 1 |
Ahmad, SM | 1 |
Cuzick, J | 1 |
Hawkey, C | 1 |
Pretel Irazabal, M | 1 |
Marques Martin, L | 1 |
Aguado Gil, L | 1 |
Idoate Gastearena, MA | 1 |
Otrock, ZK | 1 |
Degheili, JA | 1 |
Sibai, H | 1 |
Salem, ZM | 1 |
Cho, SH | 1 |
Kim, SW | 1 |
Kim, WC | 1 |
Chul-Hyun, L | 1 |
Go, BS | 1 |
Manno, D | 3 |
Fischer, Q | 1 |
Huisse, MG | 1 |
Voiriot, G | 1 |
Caron, C | 1 |
Lepage, L | 1 |
Dilly, MP | 1 |
Nataf, P | 1 |
Ajzenberg, N | 1 |
Kirsch, M | 1 |
Edwards, P | 2 |
Shakur, H | 2 |
Bennett, C | 1 |
Klingenberg, SL | 3 |
Langholz, E | 2 |
Gluud, LL | 4 |
Bilkhu, A | 1 |
Saha, A | 1 |
Ilsley, DW | 1 |
Atikah, N | 1 |
Singh, G | 1 |
Maulahela, H | 1 |
Cahyanur, R | 1 |
Flores, S | 1 |
Avilés, C | 1 |
Rada, G | 1 |
Tutchenko, MI | 1 |
Rudyk, DV | 1 |
Iskra, NI | 1 |
Trofimenko, SP | 1 |
Shchur, IV | 1 |
Jessing, TD | 1 |
Fenger-Eriksen, C | 1 |
Hu, D | 1 |
Miliam, PB | 1 |
Carron, M | 1 |
Globokar, P | 1 |
Sicard, BA | 1 |
Hansen, LF | 1 |
Wewer, V | 1 |
Pedersen, SA | 1 |
Matzen, P | 1 |
Paerregaard, A | 1 |
Kovacs, TO | 1 |
Jensen, DM | 1 |
Almadi, M | 1 |
Ghali, PM | 1 |
Constantin, A | 1 |
Galipeau, J | 1 |
Szilagyi, A | 1 |
Yadav, SP | 1 |
Sachdeva, A | 1 |
Bhat, S | 1 |
Katewa, S | 1 |
Sabovic, M | 2 |
Lavre, J | 2 |
Vujkovac, B | 2 |
Amarapurkar, DN | 1 |
Patel, ND | 1 |
Stovicek, J | 1 |
Keil, R | 1 |
Pálová, S | 1 |
Lochmannová, J | 1 |
Koseki, M | 1 |
Asada, N | 1 |
Uryu, H | 1 |
Takeuchi, M | 1 |
Asakura, H | 1 |
Matsue, K | 1 |
Langholz, SE | 1 |
Barer, D | 2 |
Ogilvie, A | 1 |
Henry, D | 1 |
Dronfield, M | 1 |
Coggon, D | 1 |
French, S | 1 |
Ellis, S | 1 |
Atkinson, M | 1 |
Langman, M | 1 |
Chalmers, TC | 1 |
Low, J | 1 |
Dodds, AJ | 2 |
Biggs, JC | 2 |
Hollanders, D | 1 |
Thomson, JM | 1 |
Schofield, PF | 1 |
Poller, L | 1 |
Bergqvist, D | 1 |
Dahlgren, S | 1 |
Hessman, Y | 1 |
Patchett, SE | 1 |
O'Donoghue, DP | 1 |
de Pont, AC | 1 |
Zandstra, DF | 1 |
Katsaros, D | 1 |
Grundfest-Broniatowski, S | 1 |
McCormick, PA | 1 |
Ooi, H | 1 |
Crosbie, O | 1 |
Baerlocher, GM | 1 |
Leoncini-Franscini, L | 1 |
Wuillemin, WA | 1 |
Furlan, M | 1 |
Meijer, K | 1 |
Peters, FT | 1 |
van der Meer, J | 1 |
Hawkey, GM | 1 |
Cole, AT | 1 |
McIntyre, AS | 1 |
Long, RG | 1 |
Hawkey, CJ | 1 |
Burak, KW | 1 |
Lee, SS | 1 |
Beck, PL | 1 |
MacLean, JE | 1 |
Cohen, E | 1 |
Weinstein, M | 1 |
Nilsson, IM | 2 |
Bergentz, SE | 1 |
Hedner, U | 1 |
Kullenberg, K | 1 |
Ostberg, HO | 1 |
Ulfberg, J | 1 |
Wennerholm, M | 1 |
Zellner, K | 1 |
Engqvist, A | 1 |
Broström, O | 1 |
von Feilitzen, F | 1 |
Halldin, M | 1 |
Nyström, B | 1 |
Ost, A | 1 |
Reichard, H | 1 |
Sandqvist, S | 1 |
Törngren, S | 1 |
Wedlund, JE | 1 |
Hugh, TB | 1 |
Prentice, CR | 1 |
Henry, DA | 1 |
O'Connell, DL | 1 |
Langman, MJ | 1 |
von Holstein, CC | 2 |
Eriksson, SB | 2 |
Källén, R | 2 |
Berstad, A | 1 |
Almodovar, K | 1 |
Berstad, K | 1 |
Anderson, W | 1 |
Hirschowitz, BI | 1 |
Isacson, S | 1 |
Hoshina, K | 1 |
Yamazaki, N | 1 |
Takeshita, T | 1 |
Naruchi, T | 1 |
Navab, F | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Tranexamic Acid for the Treatment of Gastrointestinal Haemorrhage: an International Randomised, Double Blind Placebo Controlled Trial[NCT01658124] | Phase 3 | 12,009 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321] | 60 participants (Actual) | Interventional | 2022-03-24 | Completed | |||
Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880] | Phase 4 | 25 participants (Actual) | Interventional | 2020-09-10 | Active, not recruiting | ||
Efficacy and Safety of Early Administration of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding: a Multicenter, Randomized, Double Blind, Placebo-controlled Trial (Modified by amendment1)[NCT03023189] | Phase 4 | 500 participants (Anticipated) | Interventional | 2017-04-03 | Recruiting | ||
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
The Role of Tranexamic Acid for the Treatment of Gastrointestinal Bleeding: A Randomized Double-blind Controlled Trial[NCT03540368] | 336 participants (Anticipated) | Interventional | 2018-07-04 | Suspended (stopped due to increased number of patients death) | |||
Local Administration of Tranexamic Acid in Upper Gastrointestinal Hemorrhage: A Double-Blind, Randomized, Placebo-Controlled Trial[NCT02903017] | Phase 4 | 114 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
23 reviews available for tranexamic acid and Gastrointestinal Hemorrhage
Article | Year |
---|---|
Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Length of Stay; Secondary Prevention; | 2022 |
Tranexamic acid - A narrative review for the emergency medicine clinician.
Topics: Angioedema; Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Tranex | 2022 |
Tranexamic acid and Gastrointestinal bleed: Effect of the HALT-IT trial on current meta-analysis.
Topics: Antifibrinolytic Agents; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Tranexamic A | 2022 |
Tranexamic acid in emergency medicine. An overview of reviews.
Topics: Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Subarachnoid Hemor | 2023 |
Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients.
Topics: Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Humans; Pregnancy; Tranexamic Acid; Va | 2023 |
Tranexamic acid may be a useful pharmacotherapy for endoscopically resistant small bowel angiodysplasia.
Topics: Angiodysplasia; Colonic Diseases; Gastrointestinal Hemorrhage; Humans; Telangiectasia, Hereditary He | 2023 |
Systematic review with meta-analysis: the efficacy of tranexamic acid in upper gastrointestinal bleeding.
Topics: Antifibrinolytic Agents; Blood Transfusion; Controlled Clinical Trials as Topic; Female; Gastrointes | 2020 |
Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials.
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Randomized Controlled Trials as Topic; | 2021 |
Efficacy and safety of tranexamic acid in acute upper gastrointestinal bleeding: meta-analysis of randomised controlled trials.
Topics: Blood Transfusion; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2020 |
Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
Topics: Anemia; Angiogenesis Inhibitors; Anticoagulants; Antifibrinolytic Agents; Clinical Trials as Topic; | 2021 |
How effective is tranexamic acid for acute gastrointestinal bleeding?
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr | 2014 |
Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding.
Topics: Adult; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Tranexamic Acid; | 2015 |
Is tranexamic acid effective for acute upper gastrointestinal bleeding?
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Randomized Controlled T | 2015 |
[Tranexamic acid for upper gastrointestinal bleeding].
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Risk Factors; Thromboembolism; Tranexa | 2016 |
The short-term medical management of non-variceal upper gastrointestinal bleeding.
Topics: Animals; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Hormone Antagonists; Humans; Octreot | 2008 |
Recurrent obscure gastrointestinal bleeding: dilemmas and success with pharmacological therapies. Case series and review.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Angiogenesis Inhibitors; Angiography; Animals; Antifibrinol | 2009 |
Tranexamic acid for upper gastrointestinal bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents | 2012 |
Systematic review: tranexamic acid for upper gastrointestinal bleeding.
Topics: Antifibrinolytic Agents; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Randomize | 2008 |
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome.
Topics: Adrenergic beta-Antagonists; Antifibrinolytic Agents; Diagnosis, Differential; Esophageal and Gastri | 2001 |
Local fibrinolysis as a mechanism for haemorrhage.
Topics: Aminocaproates; Endometrium; Epistaxis; Female; Fibrinolysis; Gastric Juice; Gastrointestinal Hemorr | 1975 |
Indications for antifibrinolytic therapy.
Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Disseminated Intrav | 1975 |
Tranexamic acid in acute upper gastrointestinal bleeding.
Topics: Blood Transfusion; Cyclohexanecarboxylic Acids; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 1987 |
20 trials available for tranexamic acid and Gastrointestinal Hemorrhage
Article | Year |
---|---|
A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cost-Benefit Analysis; Gastrointestinal Hemorrhag | 2021 |
A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage.
Topics: Antifibrinolytic Agents; Double-Blind Method; Endoscopy; Gastrointestinal Hemorrhage; Humans; Tranex | 2020 |
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema | 2020 |
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema | 2020 |
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema | 2020 |
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema | 2020 |
An alternative perspective to just halting tranexamic acid utilization in gastrointestinal bleeding.
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid; Treatment Outcome | 2021 |
Tranexamic acid should be avoided for acute gastrointestinal bleeds.
Topics: Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboembolism; | 2021 |
Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Digestive System Diseases; Double-Blind Met | 2018 |
Efficacy and tolerance of early administration of tranexamic acid in patients with cirrhosis presenting with acute upper gastrointestinal bleeding: a study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (the EXARHOSE study)
Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Double-Blind Method; France; Gastrointe | 2018 |
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Topics: Antifibrinolytic Agents; Data Interpretation, Statistical; Double-Blind Method; Gastrointestinal Hem | 2019 |
HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial.
Topics: Antifibrinolytic Agents; Blood Transfusion; Clinical Protocols; Double-Blind Method; Drug Administra | 2014 |
Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients.
Topics: Aged; Antifibrinolytic Agents; Combined Modality Therapy; Female; Gastrointestinal Hemorrhage; Hemos | 2003 |
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind | 1983 |
Tranexamic acid therapy in ulcerative colitis.
Topics: Adult; Aged; Colitis, Ulcerative; Cyclohexanecarboxylic Acids; Female; Gastrointestinal Hemorrhage; | 1982 |
Fibrinolysis and gastrointestinal haemorrhage.
Topics: Clinical Trials as Topic; Fibrinolysis; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Tranexa | 1980 |
Local inhibition of the fibrinolytic system in patients with massive upper gastrointestinal hemorrhage.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Bli | 1980 |
Drug treatments in upper gastrointestinal bleeding: value of endoscopic findings as surrogate end points.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Antifibrinolytic Agents; Blood Transfusi | 2001 |
Tranexamic acid in massive haemorrhage from the upper gastrointestinal tract: a double-blind study.
Topics: Aged; Alcohol Drinking; Blood Transfusion; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Do | 1979 |
Tranexamic acid and upper gastrointestinal haemorrhage--a double-blind trial.
Topics: Adolescent; Adult; Aged; Blood Coagulation Tests; Blood Transfusion; Clinical Trials as Topic; Cyclo | 1976 |
Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage.
Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Gastrointestinal Hemorrh | 1989 |
Tranexamic acid as an aid to reducing blood transfusion requirements in gastric and duodenal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Transfusion; Clinical Trials as Topic; Cyclohexane | 1987 |
Tranexamic acid in gastric and duodenal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Blood Transfusion; Cyclohexanecarboxylic Acids; Double-Blind Method; | 1987 |
55 other studies available for tranexamic acid and Gastrointestinal Hemorrhage
Article | Year |
---|---|
Tranexamic Acid in the Treatment of Refractory Gastrointestinal Arteriovenous Malformation Bleeding in Left Ventricular Assist Device Patients.
Topics: Arteriovenous Malformations; Gastrointestinal Hemorrhage; Heart Failure; Heart Ventricles; Heart-Ass | 2022 |
Is it the time to rethink how to use tranexamic acids in managing gastrointestinal bleeding?
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2022 |
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2023 |
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2023 |
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2023 |
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2023 |
Multimodality imaging approach in a patient with Klippel-Trenaunay syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Endoscopy, Digestive System | 2019 |
Use of tranexamic acid in gastrointestinal bleeding and patients with haematological malignancies.
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Hematologic Neoplasms; Humans; Tranexamic Acid | 2020 |
Tranexamic acid for severe gastrointestinal bleeding.
Topics: Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboembolism; | 2020 |
Gastrointestinal bleeding in a newborn infant with congenital factor X deficiency and COVID-19-A common clinical feature between a rare disorder and a new, common infection.
Topics: Betacoronavirus; Cesarean Section; Clinical Laboratory Techniques; Consanguinity; Coronavirus Infect | 2020 |
Tranexamic acid in acute gastrointestinal bleeding - A cautionary tale.
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2020 |
Effect of tranexamic acid in patients with colonic diverticular bleeding: A nationwide inpatient database study.
Topics: Blood Transfusion; Databases, Factual; Diverticulum, Colon; Female; Gastrointestinal Hemorrhage; Hos | 2021 |
In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days.
Topics: Adult; Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboemb | 2020 |
No role for tranexamic acid in the treatment of acute gastrointestinal bleeding.
Topics: Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2021 |
Letter: does tranexamic acid reduce the need for surgery in patients with upper gastrointestinal bleeding?
Topics: Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2020 |
Is Tranexamic Acid for Upper Gastrointestinal Bleeding Under Debate?
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2021 |
Tranexamic acid for acute gastrointestinal bleeding: updated after the HALT-IT trial.
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2021 |
Does tranexamic acid reduce 5-day death due to bleeding in acute gastrointestinal bleed?
Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2021 |
Letter: is there no conclusive evidence for the effect of tranexamic acid on mortality in gastrointestinal bleeding?
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2021 |
Application of novel magnified single balloon enteroscopy for a patient with Cronkhite-Canada syndrome.
Topics: Aged; Antifibrinolytic Agents; Biopsy; Colonoscopy; Female; Gastrointestinal Hemorrhage; Glucocortic | 2017 |
Tranexamic acid for refractory gastrointestinal bleeds: A cohort study.
Topics: Aged; Antifibrinolytic Agents; Cohort Studies; Female; Gastrointestinal Hemorrhage; Humans; Male; Mi | 2018 |
Tranexamic acid in treatment-resistant chronic transfusion-dependent gastrointestinal angiodysplasia bleeding.
Topics: Aged; Angiodysplasia; Antifibrinolytic Agents; Erythrocyte Transfusion; Female; Gastrointestinal Hem | 2017 |
Gastrointestinal tract involvement in Klippel-Trénaunay syndrome.
Topics: Antifibrinolytic Agents; Child; Colon; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Kli | 2018 |
Topical use of tranexamic acid for the management of post-procedural rectal bleeding.
Topics: Administration, Topical; Antifibrinolytic Agents; Biopsy, Needle; Emergency Service, Hospital; Gastr | 2019 |
Conservative management of diffuse cavernous haemangioma of the sigmoid and rectum.
Topics: Administration, Oral; Antifibrinolytic Agents; Colonoscopy; Conservative Treatment; Gastrointestinal | 2020 |
Tranexamic acid-induced toxic epidermal necrolysis.
Topics: Aged; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male; Stevens-J | 2013 |
Recurrent jejunal bleeding due to angiodysplasia in a Bernard-Soulier patient.
Topics: Aged; Angiodysplasia; Antifibrinolytic Agents; Bernard-Soulier Syndrome; Blood Vessels; Female; Gast | 2013 |
Hemorrhagic bullous colitis in a patient with multiple myeloma.
Topics: Aged; Amyloidosis; Antifibrinolytic Agents; Blister; Bone Density Conservation Agents; Colitis, Isch | 2013 |
Von Willebrand factor, a versatile player in gastrointestinal bleeding in left ventricular assist device recipients?
Topics: Aged; Combined Modality Therapy; Deamino Arginine Vasopressin; Embolization, Therapeutic; Erythrocyt | 2015 |
Topical use of tranexamic acid to control parastomal bleeding.
Topics: Administration, Topical; Antifibrinolytic Agents; Bandages; Esophageal and Gastric Varices; Gastroin | 2015 |
Tranexamic acid in the management of upper gastrointestinal bleeding: an evidence-based case report.
Topics: Disease Management; Evidence-Based Medicine; Female; Gastrointestinal Hemorrhage; Humans; Middle Age | 2015 |
[MODERN VIEW ON INTENSIVE THERAPY OF GASTRO-INTESTINAL HEMORRHAGE].
Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Female; Gastrointestinal Agents; Gastrointestinal | 2015 |
Emergency medicine questions: Can tranexamic acid be used to treat upper gastrointestinal bleeds?
Topics: Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2016 |
[Should we use tranexamic acid in upper gastrointestinal bleeding?].
Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 2016 |
Acute gastrointestinal haemorrhage on board a cruise ship in the Antarctic Peninsula.
Topics: Adult; Antarctic Regions; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Male; Maurit | 2016 |
Severe blue rubber bleb nevus syndrome in a neonate.
Topics: Antifibrinolytic Agents; Arteriovenous Malformations; Drug Therapy, Combination; Electrocoagulation; | 2009 |
Successful control of massive gastrointestinal bleeding following umbilical cord blood transplantation (UCBT) by use of recombinant activated factor VII (rFVIIa) and octreotide infusion.
Topics: beta-Thalassemia; Bone Marrow Transplantation; Cord Blood Stem Cell Transplantation; Delayed Graft F | 2010 |
Gastric antral vascular ectasia (GAVE) syndrome.
Topics: Aged; Anemia, Iron-Deficiency; Chronic Disease; Disease Progression; Female; Gastric Antral Vascular | 2004 |
Intestinal lymphangiectasia: a rare cause of gastrointestinal bleeding?
Topics: Adult; Antifibrinolytic Agents; Dietary Fats; Female; Gastrointestinal Hemorrhage; Gastroscopy; Huma | 2007 |
Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis.
Topics: Acute Disease; Adult; alpha-2-Antiplasmin; Antifibrinolytic Agents; Antineoplastic Agents; Antithrom | 2007 |
Cimetidine and tranexamic acid for upper-gastrointestinal-tract bleeding.
Topics: Cimetidine; Cyclohexanecarboxylic Acids; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 1983 |
Fibrinolytic activity of gastroduodenal secretions--a possible role in upper gastrointestinal haemorrhage.
Topics: Aminocaproates; Chymotrypsin; Duodenum; Electrophoresis, Polyacrylamide Gel; Fibrinolysis; Gastric J | 1980 |
Pharmacological manipulation of gastric juice: thrombelastographic assessment and implications for treatment of gastrointestinal haemorrhage.
Topics: Aprotinin; Blood Coagulation; Fibrinolysis; Gastric Acid; Gastric Juice; Gastrointestinal Hemorrhage | 1995 |
[Antifibrinolytic therapy].
Topics: Gastrointestinal Hemorrhage; Humans; Randomized Controlled Trials as Topic; Tranexamic Acid | 1995 |
Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient.
Topics: Angiodysplasia; Antifibrinolytic Agents; Colonic Diseases; Gastrointestinal Hemorrhage; Humans; Kidn | 1998 |
Successful management of visceral Klippel-Trenaunay-Weber syndrome with the antifibrinolytic agent tranexamic acid (cyclocapron): a case report.
Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Tests; Colon, Sigmoid; Disseminated Intravascular | 1998 |
Tranexamic acid for severe bleeding gastric antral vascular ectasia in cirrhosis.
Topics: Aged; Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Stomach | 1998 |
[Patient with recurrent gastrointestinal hemorrhage in acquired von Willebrand disease].
Topics: Autoantibodies; Female; Gastrointestinal Hemorrhage; Humans; Middle Aged; Recurrence; Tranexamic Aci | 1999 |
Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa.
Topics: Angiodysplasia; Blood Transfusion; Combined Modality Therapy; Deamino Arginine Vasopressin; Estrogen | 2001 |
Primary intestinal and thoracic lymphangiectasia: a response to antiplasmin therapy.
Topics: Adolescent; alpha-2-Antiplasmin; Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Human | 2002 |
Gastric fibrinolysis.
Topics: Aged; Aminocaproates; Blood Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysi | 1975 |
Fibrinolytic inhibitors for acute gastric haemorrhage.
Topics: Cyclohexanecarboxylic Acids; Fibrinolysis; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid | 1977 |
Acute gastrointestinal haemorrhage. Experience with early panendoscopy and tranexamic acid in a rural hospital.
Topics: Acute Disease; Adult; Aged; Cyclohexanecarboxylic Acids; Endoscopy; Gastrointestinal Hemorrhage; Hem | 1977 |
Drug treatment for acute upper gastrointestinal bleeding.
Topics: Acute Disease; Gastrointestinal Hemorrhage; Humans; Research Design; Tranexamic Acid | 1992 |
Upper gastrointestinal bleeding: the trials of trials.
Topics: Clinical Trials as Topic; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Peptic Ulce | 1985 |
Effect of tranexamic acid on gastric bleeding in rats.
Topics: Animals; Cyclohexanecarboxylic Acids; Fibrinolysis; Gastrointestinal Hemorrhage; Infusions, Intraven | 1988 |
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime | 1985 |
Advances in treatment of acute upper gastrointestinal hemorrhage.
Topics: Angiography; Antacids; Barium Sulfate; Cimetidine; Combined Modality Therapy; Embolization, Therapeu | 1985 |