Page last updated: 2024-11-05

tranexamic acid and Gastrointestinal Hemorrhage

tranexamic acid has been researched along with Gastrointestinal Hemorrhage in 98 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid (TXA) is an antifibrinolytic agent used to control bleeding in different circumstances."6.94A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage. ( Doğan, NÖ; Karadaş, A; Pekdemir, M; Pinar, SG; Yaka, E; Yeşil, O; Yilmaz, S, 2020)
"The current therapeutic strategy for disseminated intravascular coagulation (DIC) is limited to control of the underlying disease, and methods for the effective management of DIC have not been established."5.34Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis. ( Asada, N; Asakura, H; Koseki, M; Matsue, K; Takeuchi, M; Uryu, H, 2007)
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)."5.30Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998)
"Tranexamic acid appears to be a reasonable adjunct for the emergency medicine clinician to consider in the management of many hemorrhagic conditions and angiotensin converting enzyme inhibitor-induced angioedema."5.22Tranexamic acid - A narrative review for the emergency medicine clinician. ( Santiago, R; Wang, K, 2022)
"We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both."5.05Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983)
"The effect or oral tranexamic acid on massive upper gastrointestinal hemorrhage was evaluated in a randomized double-blind study."5.05Local inhibition of the fibrinolytic system in patients with massive upper gastrointestinal hemorrhage. ( Bergqvist, D; Dahlgren, S; Hessman, Y, 1980)
"To report a case of toxic epidermal necrolysis (TEN) induced by orally administered tranexamic acid in a patient with liver cirrhosis and acute rectal bleeding."3.79Tranexamic acid-induced toxic epidermal necrolysis. ( Aguado Gil, L; Idoate Gastearena, MA; Marques Martin, L; Pretel Irazabal, M, 2013)
" prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin."3.67Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985)
"Tranexamic acid (TXA) is a common haemorrhage control agent in both emergency department (ED) settings and intra-operatively."3.01Tranexamic acid in emergency medicine. An overview of reviews. ( Dhingra, P; Lang, E; Yeung, M, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic agent used to control bleeding in different circumstances."2.94A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage. ( Doğan, NÖ; Karadaş, A; Pekdemir, M; Pinar, SG; Yaka, E; Yeşil, O; Yilmaz, S, 2020)
"Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98)."2.94Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. ( , 2020)
"Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions."2.87Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial. ( Bendinelli, C; Carroll, R; Draganic, BD; Murray, D; Pockney, PG; Smith, SR, 2018)
"Studies were analyzed as high-dose IV tranexamic acid versus all other dosing strategies for tranexamic acid using fixed-effects models."2.82Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis. ( Antonelli, M; Dionne, JC; Hunt, BJ; Oczkowski, SJW; Raasveld, SJ; Vlaar, APJ; Wijnberge, M, 2022)
"Tranexamic acid has been shown to reduce the need for blood transfusion in surgical patients and to reduce mortality in bleeding trauma patients, with no apparent increase in thromboembolic events."2.79HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial. ( Coats, T; Edwards, P; Gilmore, I; Jairath, V; Ker, K; Manno, D; Roberts, I; Shakur, H; Stanworth, S; Veitch, A, 2014)
" In 16 episodes of bleeding TXA was used (in a dosage of 20 mg intravenously, followed for the next 4 weeks by 10 mg/kg/48 h orally), whereas in 20 other cases of bleeding, TXA was not used."2.71Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients. ( Lavre, J; Sabovic, M; Vujkovac, B, 2003)
"Treatment with tranexamic acid was associated with a 20-30% reduction in the rate of rebleeding, a 30-40% reduction (95% confidence interval 10% to 60%) in mortality."2.66Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage. ( Henry, DA; O'Connell, DL, 1989)
" Therefore, thromboembolic risk and tranexamic acid dosage should be carefully evaluated."2.53[Tranexamic acid for upper gastrointestinal bleeding]. ( Fenger-Eriksen, C; Jessing, TD, 2016)
"The current therapeutic strategy for disseminated intravascular coagulation (DIC) is limited to control of the underlying disease, and methods for the effective management of DIC have not been established."1.34Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis. ( Asada, N; Asakura, H; Koseki, M; Matsue, K; Takeuchi, M; Uryu, H, 2007)
"A patient with von Willebrand's disease had recurrent gastrointestinal bleeding from angiodysplasia, with inadequate response to von Willebrand factor substitution, medical and endoscopic treatment, and resection of affected bowel."1.31Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa. ( Meijer, K; Peters, FT; van der Meer, J, 2001)
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)."1.30Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199021 (21.43)18.7374
1990's7 (7.14)18.2507
2000's12 (12.24)29.6817
2010's27 (27.55)24.3611
2020's31 (31.63)2.80

Authors

AuthorsStudies
Roberts, I8
Shakur-Still, H3
Afolabi, A2
Akere, A1
Arribas, M3
Austin, E1
Bal, K1
Bazeer, N1
Beaumont, D2
Brenner, A2
Carrington, L1
Chaudhri, R2
Coats, T4
Gilmore, I4
Halligan, K1
Hussain, I1
Jairath, V4
Javaid, K2
Kayani, A2
Lisman, T1
Mansukhani, R2
Miners, A1
Mutti, M2
Nadeem, MA2
Pollok, R1
Prowse, D1
Simmons, J1
Stanworth, S3
Veitch, A4
Williams, J1
Dionne, JC1
Oczkowski, SJW1
Hunt, BJ1
Antonelli, M1
Wijnberge, M1
Raasveld, SJ1
Vlaar, APJ1
Fong, MW1
Morningstar-Kywi, N1
O'Connell, C1
Qureshi, U1
Han, EE1
Wang, K1
Santiago, R1
Tran, QK1
Tang, K1
Pourmand, A1
Tsai, HW2
Lee, PL4
Kang, YN5
Grocott, MPW2
Murphy, M2
Sayers, R2
Toh, CH2
Dhingra, P1
Yeung, M1
Lang, E1
Ker, K3
Fujimori, S1
Ochoco, GETD1
Enriquez, CAG1
Urgel, RJL1
Catibog, JS1
Karadaş, A1
Doğan, NÖ1
Pinar, SG1
Yeşil, O1
Pekdemir, M1
Yilmaz, S1
Yaka, E1
Stanworth, SJ2
Twum-Barimah, E1
Abdelgadir, I1
Gordon, M1
Akobeng, AK1
Perner, A1
Møller, MH1
Dorgalaleh, A1
Baghaipour, MR1
Tabibian, S1
Ghazizadeh, F1
Dabbagh, A1
Bahoush, G1
Jazebi, M1
Bahraini, M1
Fazeli, A1
Baghaipour, N1
Yousefi, F1
Roberts, LN1
Miyamoto, Y1
Ohbe, H1
Ishimaru, M1
Matsui, H1
Fushimi, K1
Yasunaga, H1
Gilbert, BW1
Rech, MA1
Yang, KS1
Hou, SK1
Chang, CC2
Horton, LC1
Feuerstein, JD1
Erasu, V1
Novak, A1
Kamal, F1
Khan, MA1
Lee-Smith, W1
Sharma, S1
Imam, Z1
Jowhar, D1
Petryna, E1
Marella, HK1
Aksionav, P1
Iqbal, U1
Tombazzi, C1
Howden, CW1
Suk, FM1
Al-Samkari, H1
Ho, YW1
Chang, CY1
Huang, HK1
Chen, YL1
Wu, MY1
Polsky, Z1
Damji, O1
Bond, C1
Ma, C1
Lin, YC1
Chen, CY1
Murata, M1
Bamba, S1
Takahashi, K1
Imaeda, H1
Nishida, A1
Inatomi, O1
Tsujikawa, T1
Kushima, R1
Sugimoto, M1
Andoh, A1
Stollings, JL1
Landsperger, JS1
Semler, MW1
Rice, TW1
Grooteman, KV1
van Geenen, EJM1
Drenth, JPH1
Smith, SR1
Murray, D1
Pockney, PG1
Bendinelli, C1
Draganic, BD1
Carroll, R1
Sepulveda, A1
Soriano, H1
Espino, A1
Heidet, M1
Amathieu, R1
Audureau, E1
Augusto, O1
Nicolazo de Barmon, V1
Rialland, A1
Schmitz, D1
Pierrang, F1
Marty, J1
Chollet-Xémard, C1
Thirion, O1
Jacob, L1
Altawil, Z1
Gendron, BJ1
Schechter-Perkins, EM1
Cotzias, E1
Rehman, SF1
Arsalani Zadeh, R1
Smith, D1
Ahmad, SM1
Cuzick, J1
Hawkey, C1
Pretel Irazabal, M1
Marques Martin, L1
Aguado Gil, L1
Idoate Gastearena, MA1
Otrock, ZK1
Degheili, JA1
Sibai, H1
Salem, ZM1
Cho, SH1
Kim, SW1
Kim, WC1
Chul-Hyun, L1
Go, BS1
Manno, D3
Fischer, Q1
Huisse, MG1
Voiriot, G1
Caron, C1
Lepage, L1
Dilly, MP1
Nataf, P1
Ajzenberg, N1
Kirsch, M1
Edwards, P2
Shakur, H2
Bennett, C1
Klingenberg, SL3
Langholz, E2
Gluud, LL4
Bilkhu, A1
Saha, A1
Ilsley, DW1
Atikah, N1
Singh, G1
Maulahela, H1
Cahyanur, R1
Flores, S1
Avilés, C1
Rada, G1
Tutchenko, MI1
Rudyk, DV1
Iskra, NI1
Trofimenko, SP1
Shchur, IV1
Jessing, TD1
Fenger-Eriksen, C1
Hu, D1
Miliam, PB1
Carron, M1
Globokar, P1
Sicard, BA1
Hansen, LF1
Wewer, V1
Pedersen, SA1
Matzen, P1
Paerregaard, A1
Kovacs, TO1
Jensen, DM1
Almadi, M1
Ghali, PM1
Constantin, A1
Galipeau, J1
Szilagyi, A1
Yadav, SP1
Sachdeva, A1
Bhat, S1
Katewa, S1
Sabovic, M2
Lavre, J2
Vujkovac, B2
Amarapurkar, DN1
Patel, ND1
Stovicek, J1
Keil, R1
Pálová, S1
Lochmannová, J1
Koseki, M1
Asada, N1
Uryu, H1
Takeuchi, M1
Asakura, H1
Matsue, K1
Langholz, SE1
Barer, D2
Ogilvie, A1
Henry, D1
Dronfield, M1
Coggon, D1
French, S1
Ellis, S1
Atkinson, M1
Langman, M1
Chalmers, TC1
Low, J1
Dodds, AJ2
Biggs, JC2
Hollanders, D1
Thomson, JM1
Schofield, PF1
Poller, L1
Bergqvist, D1
Dahlgren, S1
Hessman, Y1
Patchett, SE1
O'Donoghue, DP1
de Pont, AC1
Zandstra, DF1
Katsaros, D1
Grundfest-Broniatowski, S1
McCormick, PA1
Ooi, H1
Crosbie, O1
Baerlocher, GM1
Leoncini-Franscini, L1
Wuillemin, WA1
Furlan, M1
Meijer, K1
Peters, FT1
van der Meer, J1
Hawkey, GM1
Cole, AT1
McIntyre, AS1
Long, RG1
Hawkey, CJ1
Burak, KW1
Lee, SS1
Beck, PL1
MacLean, JE1
Cohen, E1
Weinstein, M1
Nilsson, IM2
Bergentz, SE1
Hedner, U1
Kullenberg, K1
Ostberg, HO1
Ulfberg, J1
Wennerholm, M1
Zellner, K1
Engqvist, A1
Broström, O1
von Feilitzen, F1
Halldin, M1
Nyström, B1
Ost, A1
Reichard, H1
Sandqvist, S1
Törngren, S1
Wedlund, JE1
Hugh, TB1
Prentice, CR1
Henry, DA1
O'Connell, DL1
Langman, MJ1
von Holstein, CC2
Eriksson, SB2
Källén, R2
Berstad, A1
Almodovar, K1
Berstad, K1
Anderson, W1
Hirschowitz, BI1
Isacson, S1
Hoshina, K1
Yamazaki, N1
Takeshita, T1
Naruchi, T1
Navab, F1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid for the Treatment of Gastrointestinal Haemorrhage: an International Randomised, Double Blind Placebo Controlled Trial[NCT01658124]Phase 312,009 participants (Actual)Interventional2013-07-31Completed
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321]60 participants (Actual)Interventional2022-03-24Completed
Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880]Phase 425 participants (Actual)Interventional2020-09-10Active, not recruiting
Efficacy and Safety of Early Administration of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding: a Multicenter, Randomized, Double Blind, Placebo-controlled Trial (Modified by amendment1)[NCT03023189]Phase 4500 participants (Anticipated)Interventional2017-04-03Recruiting
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527]Phase 4100 participants (Anticipated)Interventional2019-10-07Recruiting
The Role of Tranexamic Acid for the Treatment of Gastrointestinal Bleeding: A Randomized Double-blind Controlled Trial[NCT03540368]336 participants (Anticipated)Interventional2018-07-04Suspended (stopped due to increased number of patients death)
Local Administration of Tranexamic Acid in Upper Gastrointestinal Hemorrhage: A Double-Blind, Randomized, Placebo-Controlled Trial[NCT02903017]Phase 4114 participants (Actual)Interventional2016-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

23 reviews available for tranexamic acid and Gastrointestinal Hemorrhage

ArticleYear
Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.
    Critical care medicine, 2022, 03-01, Volume: 50, Issue:3

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Length of Stay; Secondary Prevention;

2022
Tranexamic acid - A narrative review for the emergency medicine clinician.
    The American journal of emergency medicine, 2022, Volume: 56

    Topics: Angioedema; Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Tranex

2022
Tranexamic acid and Gastrointestinal bleed: Effect of the HALT-IT trial on current meta-analysis.
    The American journal of emergency medicine, 2022, Volume: 59

    Topics: Antifibrinolytic Agents; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Tranexamic A

2022
Tranexamic acid in emergency medicine. An overview of reviews.
    Internal and emergency medicine, 2023, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Subarachnoid Hemor

2023
Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients.
    BMJ open, 2023, 02-22, Volume: 13, Issue:2

    Topics: Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Humans; Pregnancy; Tranexamic Acid; Va

2023
Tranexamic acid may be a useful pharmacotherapy for endoscopically resistant small bowel angiodysplasia.
    World journal of gastroenterology, 2023, Feb-21, Volume: 29, Issue:7

    Topics: Angiodysplasia; Colonic Diseases; Gastrointestinal Hemorrhage; Humans; Telangiectasia, Hereditary He

2023
Systematic review with meta-analysis: the efficacy of tranexamic acid in upper gastrointestinal bleeding.
    Alimentary pharmacology & therapeutics, 2020, Volume: 51, Issue:11

    Topics: Antifibrinolytic Agents; Blood Transfusion; Controlled Clinical Trials as Topic; Female; Gastrointes

2020
Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials.
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Randomized Controlled Trials as Topic;

2021
Efficacy and safety of tranexamic acid in acute upper gastrointestinal bleeding: meta-analysis of randomised controlled trials.
    Scandinavian journal of gastroenterology, 2020, Volume: 55, Issue:12

    Topics: Blood Transfusion; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2020
Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood, 2021, 02-18, Volume: 137, Issue:7

    Topics: Anemia; Angiogenesis Inhibitors; Anticoagulants; Antifibrinolytic Agents; Clinical Trials as Topic;

2021
How effective is tranexamic acid for acute gastrointestinal bleeding?
    BMJ (Clinical research ed.), 2014, Feb-17, Volume: 348

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2014, Nov-21, Issue:11

    Topics: Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents; Antifibrinolytic Agents; Cimetidine; Dr

2014
Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Adult; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Tranexamic Acid;

2015
Is tranexamic acid effective for acute upper gastrointestinal bleeding?
    Medwave, 2015, Dec-07, Volume: 15 Suppl 3

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Randomized Controlled T

2015
[Tranexamic acid for upper gastrointestinal bleeding].
    Ugeskrift for laeger, 2016, Apr-11, Volume: 178, Issue:15

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Risk Factors; Thromboembolism; Tranexa

2016
The short-term medical management of non-variceal upper gastrointestinal bleeding.
    Drugs, 2008, Volume: 68, Issue:15

    Topics: Animals; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Hormone Antagonists; Humans; Octreot

2008
Recurrent obscure gastrointestinal bleeding: dilemmas and success with pharmacological therapies. Case series and review.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009, Volume: 23, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Angiogenesis Inhibitors; Angiography; Animals; Antifibrinol

2009
Tranexamic acid for upper gastrointestinal bleeding.
    The Cochrane database of systematic reviews, 2012, Jan-18, Volume: 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Aluminum Hydroxide; Anti-Ulcer Agents

2012
Systematic review: tranexamic acid for upper gastrointestinal bleeding.
    Alimentary pharmacology & therapeutics, 2008, Volume: 27, Issue:9

    Topics: Antifibrinolytic Agents; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Randomize

2008
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome.
    Gut, 2001, Volume: 49, Issue:6

    Topics: Adrenergic beta-Antagonists; Antifibrinolytic Agents; Diagnosis, Differential; Esophageal and Gastri

2001
Local fibrinolysis as a mechanism for haemorrhage.
    Thrombosis et diathesis haemorrhagica, 1975, Dec-15, Volume: 34, Issue:3

    Topics: Aminocaproates; Endometrium; Epistaxis; Female; Fibrinolysis; Gastric Juice; Gastrointestinal Hemorr

1975
Indications for antifibrinolytic therapy.
    Thrombosis et diathesis haemorrhagica, 1975, Dec-15, Volume: 34, Issue:3

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Disseminated Intrav

1975
Tranexamic acid in acute upper gastrointestinal bleeding.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 137

    Topics: Blood Transfusion; Cyclohexanecarboxylic Acids; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

1987

Trials

20 trials available for tranexamic acid and Gastrointestinal Hemorrhage

ArticleYear
A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT.
    Health technology assessment (Winchester, England), 2021, Volume: 25, Issue:58

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Cost-Benefit Analysis; Gastrointestinal Hemorrhag

2021
A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage.
    European journal of gastroenterology & hepatology, 2020, Volume: 32, Issue:1

    Topics: Antifibrinolytic Agents; Double-Blind Method; Endoscopy; Gastrointestinal Hemorrhage; Humans; Tranex

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
An alternative perspective to just halting tranexamic acid utilization in gastrointestinal bleeding.
    The American journal of emergency medicine, 2021, Volume: 46

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid; Treatment Outcome

2021
Tranexamic acid should be avoided for acute gastrointestinal bleeds.
    Drug and therapeutics bulletin, 2021, Volume: 59, Issue:6

    Topics: Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboembolism;

2021
Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial.
    Diseases of the colon and rectum, 2018, Volume: 61, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Digestive System Diseases; Double-Blind Met

2018
Efficacy and tolerance of early administration of tranexamic acid in patients with cirrhosis presenting with acute upper gastrointestinal bleeding: a study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (the EXARHOSE study)
    BMJ open, 2018, 08-10, Volume: 8, Issue:8

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Double-Blind Method; France; Gastrointe

2018
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
    Trials, 2019, Jul-30, Volume: 20, Issue:1

    Topics: Antifibrinolytic Agents; Data Interpretation, Statistical; Double-Blind Method; Gastrointestinal Hem

2019
HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial.
    Trials, 2014, Nov-19, Volume: 15

    Topics: Antifibrinolytic Agents; Blood Transfusion; Clinical Protocols; Double-Blind Method; Drug Administra

2014
Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Combined Modality Therapy; Female; Gastrointestinal Hemorrhage; Hemos

2003
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
    The New England journal of medicine, 1983, Jun-30, Volume: 308, Issue:26

    Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind

1983
Tranexamic acid therapy in ulcerative colitis.
    Postgraduate medical journal, 1982, Volume: 58, Issue:676

    Topics: Adult; Aged; Colitis, Ulcerative; Cyclohexanecarboxylic Acids; Female; Gastrointestinal Hemorrhage;

1982
Fibrinolysis and gastrointestinal haemorrhage.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1980, Volume: 14

    Topics: Clinical Trials as Topic; Fibrinolysis; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Tranexa

1980
Local inhibition of the fibrinolytic system in patients with massive upper gastrointestinal hemorrhage.
    Upsala journal of medical sciences, 1980, Volume: 85, Issue:2

    Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Bli

1980
Drug treatments in upper gastrointestinal bleeding: value of endoscopic findings as surrogate end points.
    Gut, 2001, Volume: 49, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Antifibrinolytic Agents; Blood Transfusi

2001
Tranexamic acid in massive haemorrhage from the upper gastrointestinal tract: a double-blind study.
    Scandinavian journal of gastroenterology, 1979, Volume: 14, Issue:7

    Topics: Aged; Alcohol Drinking; Blood Transfusion; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Do

1979
Tranexamic acid and upper gastrointestinal haemorrhage--a double-blind trial.
    Gut, 1976, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aged; Blood Coagulation Tests; Blood Transfusion; Clinical Trials as Topic; Cyclo

1976
Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage.
    BMJ (Clinical research ed.), 1989, Apr-29, Volume: 298, Issue:6681

    Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Gastrointestinal Hemorrh

1989
Tranexamic acid as an aid to reducing blood transfusion requirements in gastric and duodenal bleeding.
    British medical journal (Clinical research ed.), 1987, Jan-03, Volume: 294, Issue:6563

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Transfusion; Clinical Trials as Topic; Cyclohexane

1987
Tranexamic acid in gastric and duodenal bleeding.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 137

    Topics: Adult; Aged; Aged, 80 and over; Blood Transfusion; Cyclohexanecarboxylic Acids; Double-Blind Method;

1987

Other Studies

55 other studies available for tranexamic acid and Gastrointestinal Hemorrhage

ArticleYear
Tranexamic Acid in the Treatment of Refractory Gastrointestinal Arteriovenous Malformation Bleeding in Left Ventricular Assist Device Patients.
    Circulation. Heart failure, 2022, Volume: 15, Issue:1

    Topics: Arteriovenous Malformations; Gastrointestinal Hemorrhage; Heart Failure; Heart Ventricles; Heart-Ass

2022
Is it the time to rethink how to use tranexamic acids in managing gastrointestinal bleeding?
    The American journal of emergency medicine, 2022, Volume: 59

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2022
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Multimodality imaging approach in a patient with Klippel-Trenaunay syndrome.
    BMJ case reports, 2019, Aug-20, Volume: 12, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Endoscopy, Digestive System

2019
Use of tranexamic acid in gastrointestinal bleeding and patients with haematological malignancies.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Hematologic Neoplasms; Humans; Tranexamic Acid

2020
Tranexamic acid for severe gastrointestinal bleeding.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboembolism;

2020
Gastrointestinal bleeding in a newborn infant with congenital factor X deficiency and COVID-19-A common clinical feature between a rare disorder and a new, common infection.
    International journal of laboratory hematology, 2020, Volume: 42, Issue:6

    Topics: Betacoronavirus; Cesarean Section; Clinical Laboratory Techniques; Consanguinity; Coronavirus Infect

2020
Tranexamic acid in acute gastrointestinal bleeding - A cautionary tale.
    Journal of thrombosis and haemostasis : JTH, 2020, Volume: 18, Issue:10

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2020
Effect of tranexamic acid in patients with colonic diverticular bleeding: A nationwide inpatient database study.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:4

    Topics: Blood Transfusion; Databases, Factual; Diverticulum, Colon; Female; Gastrointestinal Hemorrhage; Hos

2021
In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days.
    Annals of internal medicine, 2020, 10-20, Volume: 173, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Thromboemb

2020
No role for tranexamic acid in the treatment of acute gastrointestinal bleeding.
    BMJ evidence-based medicine, 2021, Volume: 26, Issue:6

    Topics: Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2021
Letter: does tranexamic acid reduce the need for surgery in patients with upper gastrointestinal bleeding?
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:6

    Topics: Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2020
Is Tranexamic Acid for Upper Gastrointestinal Bleeding Under Debate?
    Annals of emergency medicine, 2021, Volume: 77, Issue:2

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2021
Tranexamic acid for acute gastrointestinal bleeding: updated after the HALT-IT trial.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:5

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2021
Does tranexamic acid reduce 5-day death due to bleeding in acute gastrointestinal bleed?
    CJEM, 2021, Volume: 23, Issue:2

    Topics: Acute Disease; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2021
Letter: is there no conclusive evidence for the effect of tranexamic acid on mortality in gastrointestinal bleeding?
    Alimentary pharmacology & therapeutics, 2021, Volume: 54, Issue:4

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2021
Application of novel magnified single balloon enteroscopy for a patient with Cronkhite-Canada syndrome.
    World journal of gastroenterology, 2017, Jun-14, Volume: 23, Issue:22

    Topics: Aged; Antifibrinolytic Agents; Biopsy; Colonoscopy; Female; Gastrointestinal Hemorrhage; Glucocortic

2017
Tranexamic acid for refractory gastrointestinal bleeds: A cohort study.
    Journal of critical care, 2018, Volume: 43

    Topics: Aged; Antifibrinolytic Agents; Cohort Studies; Female; Gastrointestinal Hemorrhage; Humans; Male; Mi

2018
Tranexamic acid in treatment-resistant chronic transfusion-dependent gastrointestinal angiodysplasia bleeding.
    BMJ case reports, 2017, Nov-01, Volume: 2017

    Topics: Aged; Angiodysplasia; Antifibrinolytic Agents; Erythrocyte Transfusion; Female; Gastrointestinal Hem

2017
Gastrointestinal tract involvement in Klippel-Trénaunay syndrome.
    The lancet. Gastroenterology & hepatology, 2018, Volume: 3, Issue:7

    Topics: Antifibrinolytic Agents; Child; Colon; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Kli

2018
Topical use of tranexamic acid for the management of post-procedural rectal bleeding.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Biopsy, Needle; Emergency Service, Hospital; Gastr

2019
Conservative management of diffuse cavernous haemangioma of the sigmoid and rectum.
    Annals of the Royal College of Surgeons of England, 2020, Volume: 102, Issue:1

    Topics: Administration, Oral; Antifibrinolytic Agents; Colonoscopy; Conservative Treatment; Gastrointestinal

2020
Tranexamic acid-induced toxic epidermal necrolysis.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male; Stevens-J

2013
Recurrent jejunal bleeding due to angiodysplasia in a Bernard-Soulier patient.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2013, Volume: 24, Issue:4

    Topics: Aged; Angiodysplasia; Antifibrinolytic Agents; Bernard-Soulier Syndrome; Blood Vessels; Female; Gast

2013
Hemorrhagic bullous colitis in a patient with multiple myeloma.
    Endoscopy, 2013, Volume: 45 Suppl 2 UCTN

    Topics: Aged; Amyloidosis; Antifibrinolytic Agents; Blister; Bone Density Conservation Agents; Colitis, Isch

2013
Von Willebrand factor, a versatile player in gastrointestinal bleeding in left ventricular assist device recipients?
    Transfusion, 2015, Volume: 55, Issue:1

    Topics: Aged; Combined Modality Therapy; Deamino Arginine Vasopressin; Embolization, Therapeutic; Erythrocyt

2015
Topical use of tranexamic acid to control parastomal bleeding.
    Annals of the Royal College of Surgeons of England, 2015, Volume: 97, Issue:2

    Topics: Administration, Topical; Antifibrinolytic Agents; Bandages; Esophageal and Gastric Varices; Gastroin

2015
Tranexamic acid in the management of upper gastrointestinal bleeding: an evidence-based case report.
    Acta medica Indonesiana, 2015, Volume: 47, Issue:2

    Topics: Disease Management; Evidence-Based Medicine; Female; Gastrointestinal Hemorrhage; Humans; Middle Age

2015
[MODERN VIEW ON INTENSIVE THERAPY OF GASTRO-INTESTINAL HEMORRHAGE].
    Klinichna khirurhiia, 2015, Issue:10

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Female; Gastrointestinal Agents; Gastrointestinal

2015
Emergency medicine questions: Can tranexamic acid be used to treat upper gastrointestinal bleeds?
    The American journal of emergency medicine, 2016, Volume: 34, Issue:9

    Topics: Antifibrinolytic Agents; Emergency Medicine; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2016
[Should we use tranexamic acid in upper gastrointestinal bleeding?].
    Ugeskrift for laeger, 2016, 08-22, Volume: 178, Issue:34

    Topics: Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2016
Acute gastrointestinal haemorrhage on board a cruise ship in the Antarctic Peninsula.
    International maritime health, 2016, Volume: 67, Issue:4

    Topics: Adult; Antarctic Regions; Antifibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Male; Maurit

2016
Severe blue rubber bleb nevus syndrome in a neonate.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2009, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Arteriovenous Malformations; Drug Therapy, Combination; Electrocoagulation;

2009
Successful control of massive gastrointestinal bleeding following umbilical cord blood transplantation (UCBT) by use of recombinant activated factor VII (rFVIIa) and octreotide infusion.
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:1

    Topics: beta-Thalassemia; Bone Marrow Transplantation; Cord Blood Stem Cell Transplantation; Delayed Graft F

2010
Gastric antral vascular ectasia (GAVE) syndrome.
    The Journal of the Association of Physicians of India, 2004, Volume: 52

    Topics: Aged; Anemia, Iron-Deficiency; Chronic Disease; Disease Progression; Female; Gastric Antral Vascular

2004
Intestinal lymphangiectasia: a rare cause of gastrointestinal bleeding?
    Scandinavian journal of gastroenterology, 2007, Volume: 42, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Dietary Fats; Female; Gastrointestinal Hemorrhage; Gastroscopy; Huma

2007
Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis.
    International journal of hematology, 2007, Volume: 86, Issue:5

    Topics: Acute Disease; Adult; alpha-2-Antiplasmin; Antifibrinolytic Agents; Antineoplastic Agents; Antithrom

2007
Cimetidine and tranexamic acid for upper-gastrointestinal-tract bleeding.
    The New England journal of medicine, 1983, Nov-24, Volume: 309, Issue:21

    Topics: Cimetidine; Cyclohexanecarboxylic Acids; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

1983
Fibrinolytic activity of gastroduodenal secretions--a possible role in upper gastrointestinal haemorrhage.
    Thrombosis research, 1980, Mar-15, Volume: 17, Issue:6

    Topics: Aminocaproates; Chymotrypsin; Duodenum; Electrophoresis, Polyacrylamide Gel; Fibrinolysis; Gastric J

1980
Pharmacological manipulation of gastric juice: thrombelastographic assessment and implications for treatment of gastrointestinal haemorrhage.
    Gut, 1995, Volume: 36, Issue:3

    Topics: Aprotinin; Blood Coagulation; Fibrinolysis; Gastric Acid; Gastric Juice; Gastrointestinal Hemorrhage

1995
[Antifibrinolytic therapy].
    Nederlands tijdschrift voor geneeskunde, 1995, Jun-03, Volume: 139, Issue:22

    Topics: Gastrointestinal Hemorrhage; Humans; Randomized Controlled Trials as Topic; Tranexamic Acid

1995
Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 31, Issue:3

    Topics: Angiodysplasia; Antifibrinolytic Agents; Colonic Diseases; Gastrointestinal Hemorrhage; Humans; Kidn

1998
Successful management of visceral Klippel-Trenaunay-Weber syndrome with the antifibrinolytic agent tranexamic acid (cyclocapron): a case report.
    The American surgeon, 1998, Volume: 64, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Tests; Colon, Sigmoid; Disseminated Intravascular

1998
Tranexamic acid for severe bleeding gastric antral vascular ectasia in cirrhosis.
    Gut, 1998, Volume: 42, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Stomach

1998
[Patient with recurrent gastrointestinal hemorrhage in acquired von Willebrand disease].
    Therapeutische Umschau. Revue therapeutique, 1999, Volume: 56, Issue:9

    Topics: Autoantibodies; Female; Gastrointestinal Hemorrhage; Humans; Middle Aged; Recurrence; Tranexamic Aci

1999
Recurrent severe bleeding from gastrointestinal angiodysplasia in a patient with von Willebrand's disease, controlled with recombinant factor VIIa.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2001, Volume: 12, Issue:3

    Topics: Angiodysplasia; Blood Transfusion; Combined Modality Therapy; Deamino Arginine Vasopressin; Estrogen

2001
Primary intestinal and thoracic lymphangiectasia: a response to antiplasmin therapy.
    Pediatrics, 2002, Volume: 109, Issue:6

    Topics: Adolescent; alpha-2-Antiplasmin; Antifibrinolytic Agents; Female; Gastrointestinal Hemorrhage; Human

2002
Gastric fibrinolysis.
    Thrombosis et diathesis haemorrhagica, 1975, Nov-15, Volume: 34, Issue:2

    Topics: Aged; Aminocaproates; Blood Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysi

1975
Fibrinolytic inhibitors for acute gastric haemorrhage.
    British medical journal, 1977, Dec-17, Volume: 2, Issue:6102

    Topics: Cyclohexanecarboxylic Acids; Fibrinolysis; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

1977
Acute gastrointestinal haemorrhage. Experience with early panendoscopy and tranexamic acid in a rural hospital.
    Acta chirurgica Scandinavica, 1977, Volume: 143, Issue:7-8

    Topics: Acute Disease; Adult; Aged; Cyclohexanecarboxylic Acids; Endoscopy; Gastrointestinal Hemorrhage; Hem

1977
Drug treatment for acute upper gastrointestinal bleeding.
    BMJ (Clinical research ed.), 1992, Feb-08, Volume: 304, Issue:6823

    Topics: Acute Disease; Gastrointestinal Hemorrhage; Humans; Research Design; Tranexamic Acid

1992
Upper gastrointestinal bleeding: the trials of trials.
    Gut, 1985, Volume: 26, Issue:3

    Topics: Clinical Trials as Topic; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Peptic Ulce

1985
Effect of tranexamic acid on gastric bleeding in rats.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:4

    Topics: Animals; Cyclohexanecarboxylic Acids; Fibrinolysis; Gastrointestinal Hemorrhage; Infusions, Intraven

1988
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime

1985
Advances in treatment of acute upper gastrointestinal hemorrhage.
    Southern medical journal, 1985, Volume: 78, Issue:7

    Topics: Angiography; Antacids; Barium Sulfate; Cimetidine; Combined Modality Therapy; Embolization, Therapeu

1985