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tranexamic acid and Fractures, Bone

tranexamic acid has been researched along with Fractures, Bone in 10 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Fractures, Bone: Breaks in bones.

Research Excerpts

ExcerptRelevanceReference
" The ongoing trials create six new comparisons: tranexamic acid (tablet + injection) versus placebo; intravenous tranexamic acid versus oral tranexamic acid; topical tranexamic acid versus oral tranexamic acid; different intravenous tranexamic acid dosing regimes; topical tranexamic acid versus topical fibrin glue; and fibrinogen (injection) versus placebo."3.01Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures. ( Brunskill, SJ; Champaneria, R; Dorée, C; Estcourt, LJ; Geneen, LJ; Gibbs, VN; Novak, A; Palmer, AJ; Raval, P, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to be effective in reducing blood loss and the need for transfusions after several orthopaedic surgeries."2.55Efficacy and Safety of Tranexamic Acid in Orthopaedic Fracture Surgery: A Meta-Analysis and Systematic Literature Review. ( Amer, K; Amer, KM; Haydel, C; Rehman, S, 2017)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Tekin, SB1
Demir, IH1
Bozgeyik, B1
Mert, A1
Ye, L1
Guan, J1
Wang, X1
Chen, X1
Lu, H1
Xiao, Y1
Dai, X1
Wu, M1
Ma, S1
Sun, X1
Li, L1
Tan, Y1
Xia, Y1
Gibbs, VN1
Geneen, LJ1
Champaneria, R1
Raval, P1
Dorée, C1
Brunskill, SJ1
Novak, A1
Palmer, AJ1
Estcourt, LJ1
Cornell, C1
Amer, KM1
Rehman, S1
Amer, K1
Haydel, C1
Lack, WD1
Crist, BD1
Seymour, RB1
Harvin, W1
Karunakar, MA1
Chuen, CK1
Watson, J1
Kantak, A1
Panose, P1
Peck, J1
Kepecs, DM1
Mei, B1
Safir, OA1
Backstein, D1
Gross, AE1
Kuzyk, PR1
Carlin, G1
Modig, J1
Saldeen, T1
Risberg, B1
Peterson, HI1

Reviews

2 reviews available for tranexamic acid and Fractures, Bone

ArticleYear
Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures.
    The Cochrane database of systematic reviews, 2023, 06-05, Volume: 6

    Topics: Arthroplasty, Replacement; Fibrinogen; Fractures, Bone; Hemorrhage; Hemostatics; Humans; Myocardial

2023
Efficacy and Safety of Tranexamic Acid in Orthopaedic Fracture Surgery: A Meta-Analysis and Systematic Literature Review.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Fracture Fixation; Fractur

2017

Trials

2 trials available for tranexamic acid and Fractures, Bone

ArticleYear
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
Effect of Tranexamic Acid on Transfusion: A Randomized Clinical Trial in Acetabular Fracture Surgery.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Acetabulum; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; F

2017

Other Studies

6 other studies available for tranexamic acid and Fractures, Bone

ArticleYear
How does tranexamic acid affect blood transfusion and bleeding amount in pelvis-acetabulum fractures treated with open reduction and internal fixation?
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:9

    Topics: Acetabulum; Blood Loss, Surgical; Blood Transfusion; Fracture Fixation, Internal; Fractures, Bone; H

2022
Tranexamic Acid Should be Considered in Fracture Surgery.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Routes; Fracture Fixation; Fractu

2017
Low and high energy pelvic injuries.
    British journal of hospital medicine (London, England : 2005), 2018, Jul-02, Volume: 79, Issue:7

    Topics: Antifibrinolytic Agents; Braces; Emergency Medical Services; Fractures, Bone; Humans; Pelvic Bones;

2018
The Effect of Preoperative Administration of Intravenous Tranexamic Acid During Revision Hip Arthroplasty: A Retrospective Study.
    The Journal of bone and joint surgery. American volume, 2018, Sep-05, Volume: 100, Issue:17

    Topics: Acetabulum; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood

2018
Effect of infusion of dextran 70 on fibrinolysis inhibition activity in human serum.
    Acta chirurgica Scandinavica, 1979, Volume: 145, Issue:3

    Topics: Adolescent; Adult; Aged; Dextrans; Fibrinogen; Fibrinolysis; Fractures, Bone; Humans; Infusions, Par

1979
Pulmonary tissue fibrinolysis in traumatized rats pretreated with tranexamic acid.
    Microvascular research, 1977, Volume: 13, Issue:1

    Topics: Animals; Cyclohexanecarboxylic Acids; Depression, Chemical; Female; Femur; Fibrinogen; Fibrinolysis;

1977