tranexamic acid has been researched along with Femoral Fractures in 10 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Femoral Fractures: Fractures of the femur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial." | 9.41 | [Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021) |
| "To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial." | 5.41 | [Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021) |
| "This study aims to investigate the effect of tranexamic acid (TXA) on the union of closed femoral fractures using radiological and histological methods in an experimental rat model." | 3.96 | Systemic tranexamic acid promotes bone healing in a rat model of femur fracture. ( Arıcan, M; Gamsızkan, M; Karaduman, ZO; Orhan, Z; Turhal, O; Turhan, Y, 2020) |
| "Tranexamic acid has been found to be effective in reducing peri-operative blood loss and is widely used across surgical specialties including orthopaedic surgery." | 3.11 | Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions. ( Ajiboye, LO; Arojuraye, SA; Ibrahim, SS; James, JA; Jatto, HI; Ramat, AM; Shodipo, OM; Toluse, AM, 2022) |
| "Tranexamic acid (TXA) has been widely used to decrease transfusion rate in joint replacement surgery." | 2.58 | A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery. ( Bai, J; Chen, P; He, J; Liang, Y; Wang, J; Zhang, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 8 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shodipo, OM | 1 |
| Jatto, HI | 1 |
| Ramat, AM | 1 |
| Ibrahim, SS | 1 |
| Ajiboye, LO | 1 |
| Arojuraye, SA | 1 |
| James, JA | 1 |
| Toluse, AM | 1 |
| Cheng, JF | 1 |
| Qian, WQ | 1 |
| Yishake, M | 1 |
| Shen, JW | 1 |
| Pan, Z | 1 |
| Xu, T | 1 |
| Hanke, J | 1 |
| Mendel, T | 1 |
| Wingert, M | 1 |
| Schenk, P | 1 |
| Heinecke, M | 1 |
| Wilharm, A | 1 |
| Powell-Bowns, MFR | 1 |
| Olley, RK | 1 |
| McCann, C | 1 |
| Balfour, JR | 1 |
| Brennan, CM | 1 |
| Peh, J | 1 |
| Duckworth, AD | 1 |
| Scott, CEH | 1 |
| Çevik, HB | 1 |
| Eceviz, E | 1 |
| Çilingir Kaya, ÖT | 1 |
| Ercan, F | 1 |
| Çeçen, GS | 1 |
| Karaduman, ZO | 1 |
| Arıcan, M | 1 |
| Turhan, Y | 1 |
| Turhal, O | 1 |
| Orhan, Z | 1 |
| Gamsızkan, M | 1 |
| Li, H | 1 |
| Liu, D | 1 |
| Tang, X | 1 |
| Wang, N | 1 |
| Gong, D | 1 |
| Wu, Y | 1 |
| Zhang, Y | 1 |
| Li, W | 1 |
| Gou, Y | 1 |
| Zhang, P | 1 |
| Bai, J | 1 |
| He, J | 1 |
| Liang, Y | 1 |
| Chen, P | 1 |
| Wang, J | 1 |
| Spitler, CA | 1 |
| Row, ER | 1 |
| Gardner, WE | 1 |
| Swafford, RE | 1 |
| Hankins, MJ | 1 |
| Nowotarski, PJ | 1 |
| Kiner, DW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Tranexamic Acid in Reducing Requirement of Blood Transfusion in Lower Limb Trauma Surgery: A Prospective Randomized Controlled Study[NCT04986813] | Phase 4 | 100 participants (Actual) | Interventional | 2017-04-01 | Completed | ||
| Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238] | Phase 2 | 130 participants (Anticipated) | Interventional | 2023-04-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tranexamic acid and Femoral Fractures
| Article | Year |
|---|---|
A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery.
Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; | 2018 |
3 trials available for tranexamic acid and Femoral Fractures
| Article | Year |
|---|---|
Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
Topics: Adult; Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Humans; Prospecti | 2022 |
[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures].
Topics: Administration, Intravenous; Administration, Topical; Blood Loss, Surgical; Bone Nails; Femoral Frac | 2021 |
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled Trial.
Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Femoral Fractures; | 2019 |
6 other studies available for tranexamic acid and Femoral Fractures
| Article | Year |
|---|---|
Comment on article by Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum | 2022 |
Comment on Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum | 2022 |
Tranexamic acid in pertrochanteric fractures: a retrospective analysis of perioperative outcomes after fixation with a proximal femoral nail.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femoral Fractures; Humans; Postoperative Hemorrhage; | 2022 |
Intravenous Tranexamic Acid Given at Femoral Fragility Fracture Surgery Reduces Blood Transfusion Requirements Fourfold.
Topics: Administration, Intravenous; Aged, 80 and over; Anticoagulants; Blood Loss, Surgical; Blood Transfus | 2023 |
The effect of topical and systemic tranexamic acid on fracture healing in rats.
Topics: Administration, Topical; Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration | 2020 |
Systemic tranexamic acid promotes bone healing in a rat model of femur fracture.
Topics: Administration, Intravenous; Animals; Antifibrinolytic Agents; Femoral Fractures; Fracture Healing; | 2020 |