Page last updated: 2024-11-05

tranexamic acid and Femoral Fractures

tranexamic acid has been researched along with Femoral Fractures in 10 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Femoral Fractures: Fractures of the femur.

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."9.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."5.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"This study aims to investigate the effect of tranexamic acid (TXA) on the union of closed femoral fractures using radiological and histological methods in an experimental rat model."3.96Systemic tranexamic acid promotes bone healing in a rat model of femur fracture. ( Arıcan, M; Gamsızkan, M; Karaduman, ZO; Orhan, Z; Turhal, O; Turhan, Y, 2020)
"Tranexamic acid has been found to be effective in reducing peri-operative blood loss and is widely used across surgical specialties including orthopaedic surgery."3.11Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions. ( Ajiboye, LO; Arojuraye, SA; Ibrahim, SS; James, JA; Jatto, HI; Ramat, AM; Shodipo, OM; Toluse, AM, 2022)
"Tranexamic acid (TXA) has been widely used to decrease transfusion rate in joint replacement surgery."2.58A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery. ( Bai, J; Chen, P; He, J; Liang, Y; Wang, J; Zhang, P, 2018)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's8 (80.00)2.80

Authors

AuthorsStudies
Shodipo, OM1
Jatto, HI1
Ramat, AM1
Ibrahim, SS1
Ajiboye, LO1
Arojuraye, SA1
James, JA1
Toluse, AM1
Cheng, JF1
Qian, WQ1
Yishake, M1
Shen, JW1
Pan, Z1
Xu, T1
Hanke, J1
Mendel, T1
Wingert, M1
Schenk, P1
Heinecke, M1
Wilharm, A1
Powell-Bowns, MFR1
Olley, RK1
McCann, C1
Balfour, JR1
Brennan, CM1
Peh, J1
Duckworth, AD1
Scott, CEH1
Çevik, HB1
Eceviz, E1
Çilingir Kaya, ÖT1
Ercan, F1
Çeçen, GS1
Karaduman, ZO1
Arıcan, M1
Turhan, Y1
Turhal, O1
Orhan, Z1
Gamsızkan, M1
Li, H1
Liu, D1
Tang, X1
Wang, N1
Gong, D1
Wu, Y1
Zhang, Y1
Li, W1
Gou, Y1
Zhang, P1
Bai, J1
He, J1
Liang, Y1
Chen, P1
Wang, J1
Spitler, CA1
Row, ER1
Gardner, WE1
Swafford, RE1
Hankins, MJ1
Nowotarski, PJ1
Kiner, DW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Tranexamic Acid in Reducing Requirement of Blood Transfusion in Lower Limb Trauma Surgery: A Prospective Randomized Controlled Study[NCT04986813]Phase 4100 participants (Actual)Interventional2017-04-01Completed
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238]Phase 2130 participants (Anticipated)Interventional2023-04-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tranexamic acid and Femoral Fractures

ArticleYear
A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery.
    Clinical interventions in aging, 2018, Volume: 13

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical;

2018

Trials

3 trials available for tranexamic acid and Femoral Fractures

ArticleYear
Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Adult; Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Humans; Prospecti

2022
[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, May-15, Volume: 35, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Blood Loss, Surgical; Bone Nails; Femoral Frac

2021
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled Trial.
    Journal of orthopaedic trauma, 2019, Volume: 33, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Femoral Fractures;

2019

Other Studies

6 other studies available for tranexamic acid and Femoral Fractures

ArticleYear
Comment on article by Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum

2022
Comment on Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum

2022
Tranexamic acid in pertrochanteric fractures: a retrospective analysis of perioperative outcomes after fixation with a proximal femoral nail.
    BMC musculoskeletal disorders, 2022, Nov-03, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femoral Fractures; Humans; Postoperative Hemorrhage;

2022
Intravenous Tranexamic Acid Given at Femoral Fragility Fracture Surgery Reduces Blood Transfusion Requirements Fourfold.
    World journal of surgery, 2023, Volume: 47, Issue:4

    Topics: Administration, Intravenous; Aged, 80 and over; Anticoagulants; Blood Loss, Surgical; Blood Transfus

2023
The effect of topical and systemic tranexamic acid on fracture healing in rats.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:2

    Topics: Administration, Topical; Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration

2020
Systemic tranexamic acid promotes bone healing in a rat model of femur fracture.
    Joint diseases and related surgery, 2020, Volume: 31, Issue:3

    Topics: Administration, Intravenous; Animals; Antifibrinolytic Agents; Femoral Fractures; Fracture Healing;

2020