tranexamic acid has been researched along with Eyelid Diseases in 3 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Eyelid Diseases: Diseases involving the EYELIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis." | 9.27 | Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018) |
| "Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis." | 5.27 | Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018) |
| "Tranexamic acid (TXA) is an antifibrinolytic, and it was used to reduce the perioperative bleeding." | 2.61 | Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. ( Li, F; Lu, HS; Ping, WD; Sun, HF; Zhao, QM, 2019) |
| "A young girl with constant exotropia was planned for surgery." | 1.51 | Factor XIII deficiency leading to preseptal haematoma post-strabismus surgery. ( Badakere, A; Jain, M; Kekunnaya, R, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jain, M | 1 |
| Kekunnaya, R | 1 |
| Badakere, A | 1 |
| Mehdizadeh, M | 1 |
| Ghassemi, A | 1 |
| Khakzad, M | 1 |
| Mir, M | 1 |
| Nekoohesh, L | 1 |
| Moghadamnia, A | 1 |
| Bijani, A | 1 |
| Mehrbakhsh, Z | 1 |
| Ghanepur, H | 1 |
| Ping, WD | 1 |
| Zhao, QM | 1 |
| Sun, HF | 1 |
| Lu, HS | 1 |
| Li, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339] | Phase 2 | 0 participants (Actual) | Interventional | 2022-03-31 | Withdrawn (stopped due to Challenges in recruitment) | ||
| Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery[NCT04754230] | Phase 4 | 40 participants (Actual) | Interventional | 2021-06-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient-reported Visual Analog Scale - Bleeding Score Day 1. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 1 (assessed within first 24 hours following surgery)
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 5.03 |
| 1,000mg IV Tranexamic Acid | 4.82 |
Patient-reported Visual Analog Scale - Bleeding Score Day 2. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 2
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 4.47 |
| 1,000mg IV Tranexamic Acid | 3.89 |
Patient-reported Visual Analog Scale - Bleeding Score Day 3. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 3
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 2.93 |
| 1,000mg IV Tranexamic Acid | 2.29 |
Patient-reported Visual Analog Scale - Bleeding Score Day 4. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 4
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 2.12 |
| 1,000mg IV Tranexamic Acid | 1.44 |
Patient-reported Visual Analog Scale - Bleeding Score Day 5. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 5
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 1.32 |
| 1,000mg IV Tranexamic Acid | 1.15 |
Patient-reported Visual Analog Scale - Bleeding Score Day 6. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 6
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 1.36 |
| 1,000mg IV Tranexamic Acid | 0.76 |
Patient-reported Visual Analog Scale - Bleeding Score Day 7. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 7
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 0.97 |
| 1,000mg IV Tranexamic Acid | 0.72 |
Number of patients in each arm requiring evaluation by the resident service for bleeding concerns expressed by the recovery nurse (in PACU), had any follow-up visit or phone call outside of regularly scheduled follow-up (NCT04754230)
Timeframe: Day of surgery through 1 week
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| PACU | Follow-up visit | Follow-up phone call | |
| 1,000mg IV Tranexamic Acid | 0 | 1 | 2 |
| Normal Saline | 0 | 0 | 2 |
Patient-reported Visual Analog Scale - Guaze Saturation Score through Postoperative Day 7. Score range: 0 (not at all) to 10 (dripping blood). (NCT04754230)
Timeframe: Postoperative Day 2 through Postoperative Day 7
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Postoperative day 2 | Postoperative day 3 | Postoperative day 4 | Postoperative day 5 | Postoperative day 6 | Postoperative day 7 | |
| 1,000mg IV Tranexamic Acid | 4.56 | 2.09 | 0.76 | 0.40 | 0.29 | 0.28 |
| Normal Saline | 5.16 | 3.03 | 1.74 | 1.11 | 0.99 | 0.80 |
1 review available for tranexamic acid and Eyelid Diseases
| Article | Year |
|---|---|
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
1 trial available for tranexamic acid and Eyelid Diseases
| Article | Year |
|---|---|
Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis.
Topics: Adolescent; Adult; Analysis of Variance; Dexamethasone; Double-Blind Method; Drug Therapy, Combinati | 2018 |
1 other study available for tranexamic acid and Eyelid Diseases
| Article | Year |
|---|---|
Factor XIII deficiency leading to preseptal haematoma post-strabismus surgery.
Topics: Antifibrinolytic Agents; Child; Exotropia; Eyelid Diseases; Factor XIII Deficiency; Female; Hematoma | 2019 |