Page last updated: 2024-11-05

tranexamic acid and Erythema

tranexamic acid has been researched along with Erythema in 14 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
" Studies have revealed reduction of erythema by oral tranexamic acid; however, there has been no direct comparison to placebo."9.41Effect of oral tranexamic acid on erythema index in patients with melasma. ( Nguyen, J; Paul, E; Rajgopal Bala, H; Rodrigues, M; Ross, A; Wong, CC, 2021)
"In this prospective pilot study, we evaluated the efficacy and safety for a novel combination therapy based on low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's melanosis."7.85A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis. ( Choi, SC; Jung, JY; Kwon, HH; Kwon, IH; Ohn, J; Park, GH; Park, HY; Suh, DH, 2017)
"Acne vulgaris is a common skin disease that is more common in young population and it can be associated with some sequels after resolving the lesions."7.30Evaluating the effect of tranexamic acid as mesotherapy on persistent post-acne erythema: A before and after study. ( Abouie, A; Bazargan, AS; Gheisari, M; Mirahmadi, S; Taheri, A; Ziaeifar, E, 2023)
"We included 20 patients, having erythematotelangiectatic rosacea."6.90The new therapeutic choice of tranexamic acid solution in treatment of erythematotelangiectatic rosacea. ( Bageorgou, F; Kontochristopoulos, G; Tzanetakou, V; Vasalou, V, 2019)
"Post-acne hyperpigmentation is a common undesirable sequela of acne vulgaris that causes distress for many patients."5.62Tranexamic acid versus fractional carbon dioxide laser in post-acne hyperpigmentation. ( Abdel Hay, R; Elmasry, MF; Salim, H; Tawfic, SO, 2021)
" Studies have revealed reduction of erythema by oral tranexamic acid; however, there has been no direct comparison to placebo."5.41Effect of oral tranexamic acid on erythema index in patients with melasma. ( Nguyen, J; Paul, E; Rajgopal Bala, H; Rodrigues, M; Ross, A; Wong, CC, 2021)
"In this prospective pilot study, we evaluated the efficacy and safety for a novel combination therapy based on low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's melanosis."3.85A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis. ( Choi, SC; Jung, JY; Kwon, HH; Kwon, IH; Ohn, J; Park, GH; Park, HY; Suh, DH, 2017)
"Acne vulgaris is a common skin disease that is more common in young population and it can be associated with some sequels after resolving the lesions."3.30Evaluating the effect of tranexamic acid as mesotherapy on persistent post-acne erythema: A before and after study. ( Abouie, A; Bazargan, AS; Gheisari, M; Mirahmadi, S; Taheri, A; Ziaeifar, E, 2023)
"Treatment of melasma is challenging."3.11A prospective randomized controlled trial of Q-switched Nd:YAG laser with topical 3% tranexamic acid (TA) versus microneedling with topical 3% tranexamic acid (TA) in treatment of melasma. ( Debasmita, B; Ipsita, D; Ishan, A; Raj, C, 2022)
"Tranexamic acid (TXA) has emerged as a potential treatment for melasma."3.01The efficacy of oral vs different dilutions of intradermal tranexamic acid microinjections in melasma-A randomized clinical trial. ( El Hadidi, H; Mosaad, R; Ragab, N, 2021)
"We included 20 patients, having erythematotelangiectatic rosacea."2.90The new therapeutic choice of tranexamic acid solution in treatment of erythematotelangiectatic rosacea. ( Bageorgou, F; Kontochristopoulos, G; Tzanetakou, V; Vasalou, V, 2019)
"Tranexamic acid (TA) is a relatively new brightening agent that interferes with keratinocyte-melanocyte interactions."2.87Comparing the efficacy of topical hydroquinone 2% versus intradermal tranexamic acid microinjections in treating melasma: a split-face controlled trial. ( Darayesh, M; Heiran, A; Saki, N, 2018)
"Melasma is a highly prevalent, chronic, and pigmentary disorder."2.58Tranexamic Acid for Adults with Melasma: A Systematic Review and Meta-Analysis. ( Fang, QQ; Gao, J; Tan, WQ; Wang, XW; Zhang, L; Zhao, QM; Zhao, WY, 2018)
"Post-acne hyperpigmentation is a common undesirable sequela of acne vulgaris that causes distress for many patients."1.62Tranexamic acid versus fractional carbon dioxide laser in post-acne hyperpigmentation. ( Abdel Hay, R; Elmasry, MF; Salim, H; Tawfic, SO, 2021)
"Tranexamic acid (TA) is a traditional plasmin inhibitor, and its role in the renovation of damaged skin has become the topic of a lot of research."1.40Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin. ( Wang, XM; Wu, PL; Yang, LJ; Yuan, C, 2014)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (57.14)24.3611
2020's6 (42.86)2.80

Authors

AuthorsStudies
Debasmita, B1
Raj, C1
Ishan, A1
Ipsita, D1
Bazargan, AS1
Ziaeifar, E1
Abouie, A1
Mirahmadi, S1
Taheri, A1
Gheisari, M1
Jakhar, D1
Kaur, I1
Nguyen, J1
Rajgopal Bala, H1
Ross, A1
Wong, CC1
Paul, E1
Rodrigues, M1
El Hadidi, H1
Mosaad, R1
Ragab, N1
Tawfic, SO1
Abdel Hay, R1
Salim, H1
Elmasry, MF1
Xu, Y1
Ma, R1
Juliandri, J1
Wang, X1
Xu, B1
Wang, D1
Lu, Y1
Zhou, B1
Luo, D1
Saki, N1
Darayesh, M1
Heiran, A1
Bageorgou, F1
Vasalou, V1
Tzanetakou, V1
Kontochristopoulos, G1
Zhang, L1
Tan, WQ1
Fang, QQ1
Zhao, WY1
Zhao, QM1
Gao, J1
Wang, XW1
Yuan, C1
Wang, XM1
Yang, LJ1
Wu, PL1
Kwon, HH1
Ohn, J1
Suh, DH1
Park, HY1
Choi, SC1
Jung, JY1
Kwon, IH1
Park, GH1
Chae, JB1
Yang, SH1
Byun, SY1
Choi, HR1
Shin, JW1
Park, KC1
Kanechorn Na Ayuthaya, P1
Niumphradit, N1
Manosroi, A1
Nakakes, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid Versus Fractional CO2 Laser in Post-inflammatory Hyperpigmentation in Acne Patients[NCT03765021]25 participants (Anticipated)Interventional2018-12-31Not yet recruiting
Comparing Tranexamic Acid Microinjection Alone Versus Its Combination With Fractional Carbon Dioxide Laser in Melasma Treatment[NCT03899233]Phase 425 participants (Anticipated)Interventional2019-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tranexamic acid and Erythema

ArticleYear
Tranexamic Acid for Adults with Melasma: A Systematic Review and Meta-Analysis.
    BioMed research international, 2018, Volume: 2018

    Topics: Adolescent; Adult; Case-Control Studies; Erythema; Humans; Melanins; Melanosis; Middle Aged; Publica

2018

Trials

8 trials available for tranexamic acid and Erythema

ArticleYear
A prospective randomized controlled trial of Q-switched Nd:YAG laser with topical 3% tranexamic acid (TA) versus microneedling with topical 3% tranexamic acid (TA) in treatment of melasma.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:7

    Topics: Erythema; Humans; Lasers, Solid-State; Melanosis; Prospective Studies; Tranexamic Acid; Treatment Ou

2022
Evaluating the effect of tranexamic acid as mesotherapy on persistent post-acne erythema: A before and after study.
    Journal of cosmetic dermatology, 2023, Volume: 22, Issue:10

    Topics: Acne Vulgaris; Erythema; Humans; Mesotherapy; Tranexamic Acid; Treatment Outcome

2023
Effect of oral tranexamic acid on erythema index in patients with melasma.
    The Australasian journal of dermatology, 2021, Volume: 62, Issue:2

    Topics: Administration, Oral; Adult; Dermatologic Agents; Erythema; Humans; Melanosis; Middle Aged; Severity

2021
The efficacy of oral vs different dilutions of intradermal tranexamic acid microinjections in melasma-A randomized clinical trial.
    Dermatologic therapy, 2021, Volume: 34, Issue:3

    Topics: Administration, Cutaneous; Erythema; Female; Humans; Melanosis; Microinjections; Tranexamic Acid; Tr

2021
Efficacy of functional microarray of microneedles combined with topical tranexamic acid for melasma: A randomized, self-controlled, split-face study.
    Medicine, 2017, Volume: 96, Issue:19

    Topics: Administration, Cutaneous; Adult; Antifibrinolytic Agents; China; Elasticity; Erythema; Face; Female

2017
Comparing the efficacy of topical hydroquinone 2% versus intradermal tranexamic acid microinjections in treating melasma: a split-face controlled trial.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:4

    Topics: Administration, Topical; Adult; Erythema; Face; Female; Humans; Hydroquinones; Melanins; Melanosis;

2018
The new therapeutic choice of tranexamic acid solution in treatment of erythematotelangiectatic rosacea.
    Journal of cosmetic dermatology, 2019, Volume: 18, Issue:2

    Topics: Acupuncture Therapy; Adult; Aged; Antifibrinolytic Agents; Bandages; Combined Modality Therapy; Derm

2019
Topical 5% tranexamic acid for the treatment of melasma in Asians: a double-blind randomized controlled clinical trial.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2012, Volume: 14, Issue:3

    Topics: Administration, Cutaneous; Adult; Antifibrinolytic Agents; Asian People; Bleaching Agents; Double-Bl

2012

Other Studies

5 other studies available for tranexamic acid and Erythema

ArticleYear
Topical 5% tranexamic acid for acne-related postinflammatory erythema.
    Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:6

    Topics: Acne Vulgaris; Administration, Cutaneous; Antifibrinolytic Agents; Erythema; Humans; Tranexamic Acid

2020
Tranexamic acid versus fractional carbon dioxide laser in post-acne hyperpigmentation.
    Dermatologic therapy, 2021, Volume: 34, Issue:6

    Topics: Acne Vulgaris; Cicatrix; Erythema; Humans; Hyperpigmentation; Lasers, Gas; Tranexamic Acid; Treatmen

2021
Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin.
    International journal of dermatology, 2014, Volume: 53, Issue:8

    Topics: Adult; Aged; Antifibrinolytic Agents; Erythema; Female; Humans; Male; Melanins; Middle Aged; Occludi

2014
A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis.
    The Journal of dermatological treatment, 2017, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Combined Modality Therapy; Erythema; Facial

2017
The effects of hydroporation on melasma with anti-aging cocktail.
    Journal of cosmetic dermatology, 2017, Volume: 16, Issue:4

    Topics: Antifibrinolytic Agents; beta-Glucans; Collagen Type IV; Copper; Dermatologic Agents; Dermis; Drug C

2017