tranexamic acid has been researched along with Ecchymosis in 16 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Ecchymosis: Extravasation of blood into the skin, resulting in a nonelevated, rounded or irregular, blue or purplish patch, larger than a petechia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis." | 9.27 | Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018) |
| "The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)." | 9.20 | The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015) |
| "To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty." | 9.01 | Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019) |
| "To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty." | 8.98 | Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018) |
| "Tranexamic acid (TXA) has gained increasing recognition in plastic surgery as a dependable adjunct capable of minimizing blood loss, ecchymosis, and edema." | 8.02 | Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis. ( Banuelos, J; Molinar, VE; Tran, NV; Weissler, JM, 2021) |
| "The aim of the present study is to examine the effect of local administration of tranexamic acid (TXA) through lateral osteotomy line on postoperative periorbital edema and ecchymosis." | 8.02 | The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty. ( Bezgin, SÜ; Çakabay, T; Çelebi, Ş; İpek, HD, 2021) |
| "Previous studies have shown that systemic tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients." | 8.02 | Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Park, HJ, 2021) |
| "Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis." | 5.27 | Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018) |
| "The aim of this randomized double-blind study was to evaluate the efficacy of Tranexamic acid (TXA) on intraoperative bleeding, postoperative eyelid edema, and postoperative periorbital ecchymosis in rhinoplasty." | 5.24 | Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study. ( Chavoshzadeh, MA; Ghavimi, MA; Ghoreishizadeh, A; Taheri Talesh, K; Zarandi, A, 2017) |
| "The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)." | 5.20 | The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015) |
| "To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty." | 5.01 | Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019) |
| "To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty." | 4.98 | Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018) |
| "Tranexamic acid (TXA) has gained increasing recognition in plastic surgery as a dependable adjunct capable of minimizing blood loss, ecchymosis, and edema." | 4.02 | Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis. ( Banuelos, J; Molinar, VE; Tran, NV; Weissler, JM, 2021) |
| "The aim of the present study is to examine the effect of local administration of tranexamic acid (TXA) through lateral osteotomy line on postoperative periorbital edema and ecchymosis." | 4.02 | The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty. ( Bezgin, SÜ; Çakabay, T; Çelebi, Ş; İpek, HD, 2021) |
| "Previous studies have shown that systemic tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients." | 4.02 | Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Park, HJ, 2021) |
| "Edema and ecchymosis were the two most investigated outcomes." | 2.82 | Complications Associated with Rhinoplasty: An Umbrella Review of Meta-analyses. ( Chen, S; Sun, K; Wu, B; Xu, X, 2022) |
| "Tranexamic acid (TXA) is an antifibrinolytic, and it was used to reduce the perioperative bleeding." | 2.61 | Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. ( Li, F; Lu, HS; Ping, WD; Sun, HF; Zhao, QM, 2019) |
| "Tranexamic acid (TXA) has been widely used as an antifibrinolytic in dentoalveolar surgery and only recently has its effects been explored in facial procedures." | 1.62 | The Use of Tranexamic Acid in Facial Cosmetic Surgery Procedures: A Technical Note. ( Christensen, BJ; Fathimani, K; Perenack, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 8 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laikhter, E | 1 |
| Comer, CD | 1 |
| Shiah, E | 1 |
| Manstein, SM | 1 |
| Bain, PA | 1 |
| Lin, SJ | 1 |
| Wu, B | 1 |
| Chen, S | 1 |
| Sun, K | 1 |
| Xu, X | 1 |
| Wang, S | 1 |
| Yang, J | 1 |
| Lin, L | 1 |
| Wang, HY | 1 |
| Wang, L | 1 |
| Luo, ZY | 1 |
| Wang, D | 1 |
| Tang, X | 1 |
| Zhou, ZK | 1 |
| Pei, FX | 1 |
| Weissler, JM | 1 |
| Banuelos, J | 1 |
| Molinar, VE | 1 |
| Tran, NV | 1 |
| İpek, HD | 1 |
| Bezgin, SÜ | 1 |
| Çakabay, T | 1 |
| Çelebi, Ş | 1 |
| Choi, YJ | 1 |
| Park, HJ | 1 |
| Lee, HJ | 1 |
| Lee, GY | 1 |
| Kim, WS | 1 |
| Hunstad, J | 1 |
| Alsubaie, S | 1 |
| Fathimani, K | 1 |
| Perenack, J | 1 |
| Christensen, BJ | 1 |
| Ghavimi, MA | 1 |
| Taheri Talesh, K | 1 |
| Ghoreishizadeh, A | 1 |
| Chavoshzadeh, MA | 1 |
| Zarandi, A | 1 |
| Mehdizadeh, M | 1 |
| Ghassemi, A | 1 |
| Khakzad, M | 1 |
| Mir, M | 1 |
| Nekoohesh, L | 1 |
| Moghadamnia, A | 1 |
| Bijani, A | 1 |
| Mehrbakhsh, Z | 1 |
| Ghanepur, H | 1 |
| Berkowitz, RL | 1 |
| de Vasconcellos, SJA | 1 |
| do Nascimento-Júnior, EM | 1 |
| de Aguiar Menezes, MV | 1 |
| Tavares Mendes, ML | 1 |
| de Souza Dantas, R | 1 |
| Martins-Filho, PRS | 1 |
| McGuire, C | 1 |
| Nurmsoo, S | 1 |
| Samargandi, OA | 1 |
| Bezuhly, M | 1 |
| Ping, WD | 1 |
| Zhao, QM | 1 |
| Sun, HF | 1 |
| Lu, HS | 1 |
| Li, F | 1 |
| Sakallioğlu, Ö | 1 |
| Polat, C | 1 |
| Soylu, E | 1 |
| Düzer, S | 1 |
| Orhan, İ | 1 |
| Akyiğit, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Extended Postoperative Tranexamic Acid Use in Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial[NCT05099276] | Phase 4 | 46 participants (Actual) | Interventional | 2021-12-07 | Active, not recruiting | ||
| Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis[NCT05774717] | Phase 1 | 60 participants (Anticipated) | Interventional | 2023-04-01 | Recruiting | ||
| Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339] | Phase 2 | 0 participants (Actual) | Interventional | 2022-03-31 | Withdrawn (stopped due to Challenges in recruitment) | ||
| Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery[NCT04754230] | Phase 4 | 40 participants (Actual) | Interventional | 2021-06-17 | Completed | ||
| The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-08-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient-reported Visual Analog Scale - Bleeding Score Day 1. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 1 (assessed within first 24 hours following surgery)
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 5.03 |
| 1,000mg IV Tranexamic Acid | 4.82 |
Patient-reported Visual Analog Scale - Bleeding Score Day 2. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 2
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 4.47 |
| 1,000mg IV Tranexamic Acid | 3.89 |
Patient-reported Visual Analog Scale - Bleeding Score Day 3. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 3
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 2.93 |
| 1,000mg IV Tranexamic Acid | 2.29 |
Patient-reported Visual Analog Scale - Bleeding Score Day 4. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 4
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 2.12 |
| 1,000mg IV Tranexamic Acid | 1.44 |
Patient-reported Visual Analog Scale - Bleeding Score Day 5. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 5
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 1.32 |
| 1,000mg IV Tranexamic Acid | 1.15 |
Patient-reported Visual Analog Scale - Bleeding Score Day 6. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 6
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 1.36 |
| 1,000mg IV Tranexamic Acid | 0.76 |
Patient-reported Visual Analog Scale - Bleeding Score Day 7. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 7
| Intervention | score on a scale (Mean) |
|---|---|
| Normal Saline | 0.97 |
| 1,000mg IV Tranexamic Acid | 0.72 |
Number of patients in each arm requiring evaluation by the resident service for bleeding concerns expressed by the recovery nurse (in PACU), had any follow-up visit or phone call outside of regularly scheduled follow-up (NCT04754230)
Timeframe: Day of surgery through 1 week
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| PACU | Follow-up visit | Follow-up phone call | |
| 1,000mg IV Tranexamic Acid | 0 | 1 | 2 |
| Normal Saline | 0 | 0 | 2 |
Patient-reported Visual Analog Scale - Guaze Saturation Score through Postoperative Day 7. Score range: 0 (not at all) to 10 (dripping blood). (NCT04754230)
Timeframe: Postoperative Day 2 through Postoperative Day 7
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Postoperative day 2 | Postoperative day 3 | Postoperative day 4 | Postoperative day 5 | Postoperative day 6 | Postoperative day 7 | |
| 1,000mg IV Tranexamic Acid | 4.56 | 2.09 | 0.76 | 0.40 | 0.29 | 0.28 |
| Normal Saline | 5.16 | 3.03 | 1.74 | 1.11 | 0.99 | 0.80 |
6 reviews available for tranexamic acid and Ecchymosis
| Article | Year |
|---|---|
A Systematic Review and Meta-Analysis Evaluating the Impact of Tranexamic Acid Administration in Aesthetic Plastic Surgery.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Female; Hematoma; Humans; Surgery, Plasti | 2022 |
Complications Associated with Rhinoplasty: An Umbrella Review of Meta-analyses.
Topics: Ecchymosis; Edema; Humans; Osteotomy; Rhinoplasty; Tranexamic Acid; Treatment Outcome | 2022 |
Local Application of Tranexamic Acid in Plastic Surgery Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Randomized Controlled Trials as T | 2023 |
Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Schedule; Ecchymosis; Edema; Eyel | 2018 |
Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Humans; Postoperative Complication | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur | 2019 |
4 trials available for tranexamic acid and Ecchymosis
| Article | Year |
|---|---|
Intravenous and subsequent long-term oral tranexamic acid in enhanced-recovery primary total knee arthroplasty without the application of a tourniquet: a randomized placebo-controlled trial.
Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L | 2019 |
Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study.
Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Ecchymosis; Edema; Female | 2017 |
Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis.
Topics: Adolescent; Adult; Analysis of Variance; Dexamethasone; Double-Blind Method; Drug Therapy, Combinati | 2018 |
The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty.
Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration | 2015 |
6 other studies available for tranexamic acid and Ecchymosis
| Article | Year |
|---|---|
Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Lipectomy; Postoperative Hemorrha | 2021 |
The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty.
Topics: Ecchymosis; Edema; Humans; Postoperative Complications; Rhinoplasty; Tranexamic Acid | 2021 |
Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Dermatologic Surgical | 2021 |
Commentary on: Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis.
Topics: Blood Loss, Surgical; Ecchymosis; Humans; Lipectomy; Surgeons; Tranexamic Acid | 2021 |
The Use of Tranexamic Acid in Facial Cosmetic Surgery Procedures: A Technical Note.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Surgery, Plastic; Tranexamic Acid | 2021 |
Commentary on: "Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-rhinoplasty and Edema and Ecchymosis".
Topics: Dexamethasone; Ecchymosis; Edema; Humans; Osteotomy; Postoperative Complications; Rhinoplasty; Trane | 2018 |