Page last updated: 2024-11-05

tranexamic acid and Duodenal Ulcer

tranexamic acid has been researched along with Duodenal Ulcer in 8 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both."5.05Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983)
"Practice is variable, even in areas with established evidence based on randomized controlled studies, such as dosage and way of administration and duration of PPI treatment, injection treatment used as monotherapy and the volume used, including ulcers with clots for treatment, and the use of scheduled second-look endoscopy."1.34Clinical practice and evidence in endoscopic treatment of bleeding peptic gastroduodenal ulcer. ( Adamsen, S; Bendix, J; Kallehave, F; Moesgaard, F; Nilsson, T; Wille-Jørgensen, P, 2007)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bagnenko, SF1
Verbitskiĭ, VG1
Adamsen, S2
Bendix, J1
Kallehave, F1
Moesgaard, F1
Nilsson, T1
Wille-Jørgensen, P1
de Muckadell, OB1
Barer, D1
Ogilvie, A1
Henry, D1
Dronfield, M1
Coggon, D1
French, S1
Ellis, S1
Atkinson, M1
Langman, M2
Yu, JY1
Wang, TH1
Wang, CY1
Chen, RR1
Sung, JL1
Katschinski, B1
Logan, R1
Davies, J1
Faulkner, G1
Pearson, J1
Bianchi Porro, G1
Ardizzone, S1
Petrillo, M1
Langman, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of High Dose Infusion and Low Dose Bolus Intravenous Omeprazole for Treatment of Bleeding Ulcer With Adherent Clot[NCT02536989]Phase 440 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tranexamic acid and Duodenal Ulcer

ArticleYear
[Treatment of bleeding gastroduodenal ulcer].
    Ugeskrift for laeger, 2007, Apr-23, Volume: 169, Issue:17

    Topics: Antacids; Antifibrinolytic Agents; Duodenal Ulcer; Duodenoscopy; Embolization, Therapeutic; Epinephr

2007

Trials

6 trials available for tranexamic acid and Duodenal Ulcer

ArticleYear
[Antifibrinolitic therapy for the treatment of massive ulcerative gastro-intestinal bleedings].
    Khirurgiia, 2011, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Dose-Response Relationship, Drug; Duodenal Ulcer; Endoscopy, Gastroin

2011
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
    The New England journal of medicine, 1983, Jun-30, Volume: 308, Issue:26

    Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind

1983
[Cetraxate in duodenal ulcer, a double-blind clinical study (author's transl)].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1981, Volume: 80, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method

1981
Prognostic factors in upper gastrointestinal bleeding.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Duodenal Ulcer; Female

1994
Cetraxate is not superior to placebo in the treatment of duodenal ulcer.
    Journal of clinical gastroenterology, 1990, Volume: 12, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Cyclohexanecarboxylic Acids; Double-Blind Method; Duodenal Ulc

1990
Drug treatment for haematemesis and melaena.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 2

    Topics: Clinical Trials as Topic; Duodenal Ulcer; Hematemesis; Histamine H2 Antagonists; Humans; Laser Thera

1986

Other Studies

1 other study available for tranexamic acid and Duodenal Ulcer

ArticleYear
Clinical practice and evidence in endoscopic treatment of bleeding peptic gastroduodenal ulcer.
    Scandinavian journal of gastroenterology, 2007, Volume: 42, Issue:3

    Topics: Anesthetics; Antifibrinolytic Agents; Denmark; Drug Prescriptions; Duodenal Ulcer; Epinephrine; Evid

2007