Page last updated: 2024-11-05

tranexamic acid and Deep Vein Thrombosis

tranexamic acid has been researched along with Deep Vein Thrombosis in 115 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
" The purpose of this study was to assess the safety of tranexamic acid (TXA) utilization with respect to the incidence of deep venous thrombosis (DVT) in hemophiliacs undergoing total knee arthroplasty (TKA)."9.69Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study. ( Guo, JJ; Yu, Z; Zhang, Q; Zhao, L, 2023)
"Background and Objectives: Previous studies regarding tranexamic acid (TXA) in total knee arthroplasty (TKA) investigated only symptomatic deep vein thrombosis (DVT), or did not include high risk patients."8.12Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients. ( An, BK; Joo, YB; Kim, YM; Kwon, ST; Lee, CW; Song, JH, 2022)
"Tranexamic acid (TXA) is used as a hemostatic adjunct for hemorrhage control in the injured patient and reduces early preventable death."7.91Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism. ( Brown, JB; Kutcher, ME; Myers, SP; Neal, MD; Peitzman, AB; Rosengart, MR; Sperry, JL, 2019)
"The major concern with the use of tranexamic acid is that it may promote a hypercoagulable state and increase the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE), particularly when chemical thromboprophylaxis is not used."7.85Chemical Thromboprophylaxis Is Not Necessary to Reduce Risk of Thromboembolism With Tranexamic Acid After Total Hip Arthroplasty. ( Kim, JS; Kim, YH; Park, JW, 2017)
" The purpose of this study was to assess the safety of tranexamic acid (TXA) utilization with respect to the incidence of deep venous thrombosis (DVT) in hemophiliacs undergoing total knee arthroplasty (TKA)."5.69Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study. ( Guo, JJ; Yu, Z; Zhang, Q; Zhao, L, 2023)
"VTE recurrence was not significantly greater in those who received TXA (2."5.46Tranexamic Acid Was Safe in Arthroplasty Patients With a History of Venous Thromboembolism: A Matched Outcome Study. ( Abdel, MP; Amundson, AW; Larson, DR; Pagnano, MW; Sabbag, OD, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic that reduces blood loss after THA and TKA."5.43Balancing Thromboprophylaxis and Bleeding in Total Joint Arthroplasty: Impact of Eliminating Enoxaparin and Predonation and Implementing Pneumatic Compression and Tranexamic Acid. ( Campbell, JC; Mirocha, JM; Sharfman, ZT; Spitzer, AI, 2016)
"Tranexamic acid (TXA) has been used to reduce blood loss during total hip arthroplasty (THA), but its use could increase the risk of venous thromboembolic disease (VTE)."5.42Does tranexamic acid alter the risk of thromboembolism after total hip arthroplasty in the absence of routine chemical thromboprophylaxis? ( Hamada, M; Nishihara, S, 2015)
"We examined the blood conserving effect of tranexamic acid in total hip arthroplasty using the direct anterior approach with enoxaparin as deep vein thrombosis (DVT) chemoprophylaxis, and whether this translates to an effect on functional outcomes in the perioperative period."5.30OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial. ( Duggan, J; Duncan, S; Fraval, A; Murray, T; Tirosh, O; Tran, P, 2019)
"The objective of this study was to ascertain whether combined intravenous (IV) and intra-articular (IA) administration of tranexamic acid (TXA) is beneficial for reducing blood loss and the prevalence of deep venous thrombosis (DVT) in primary simultaneous bilateral total knee arthroplasty compared with IV only administration of TXA."5.27Comparative Efficacy of Intravenous With Intra-articular Versus Intravenous Only Administration of Tranexamic Acid to Reduce Blood Loss in Knee Arthroplasty. ( Kim, JS; Kim, YH; Pandey, K; Park, JW, 2018)
"Systemic administration of TXA can effectively reduce the postoperative blood loss which results in lower rate of transfusion requirement and wound hematoma in minimally invasive TKA patients when rivaroxaban is used for thromboprophylaxis."5.24The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial. ( Chen, B; Huang, CC; Kuo, FC; Lin, PC; Wang, JW; Yen, SH, 2017)
"This systematic review was undertaken to answer three specific questions relating to the clinical values of tranexamic acid (TNA) in total knee arthroplasty (TKA): (1) Whether there are differences in blood-saving effects between the systemic and topical administrations; (2) Whether blood-saving effects of TNA differ by doses and timings of administration; and (3) Whether the use of TNA is safe at all reported doses, timings, and routes of administration with respect to the incidences of symptomatic deep-vein thrombosis (DVT) and pulmonary embolism (PE)."4.90Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review. ( Chang, CB; Kim, TK; Koh, IJ, 2014)
"Background and Objectives: Previous studies regarding tranexamic acid (TXA) in total knee arthroplasty (TKA) investigated only symptomatic deep vein thrombosis (DVT), or did not include high risk patients."4.12Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients. ( An, BK; Joo, YB; Kim, YM; Kwon, ST; Lee, CW; Song, JH, 2022)
"Tranexamic acid (TXA) is used as a hemostatic adjunct for hemorrhage control in the injured patient and reduces early preventable death."3.91Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism. ( Brown, JB; Kutcher, ME; Myers, SP; Neal, MD; Peitzman, AB; Rosengart, MR; Sperry, JL, 2019)
"To ascertain whether tranexamic acid reduces the blood loss and transfusion rate and volumes; increase the prevalence of deep vein thrombosis (DVT); and investigate factors associated with DVT in patients undergoing primary bilateral total knee arthroplasties (TKAs) without use of chemical thromboprophylaxis."3.88Does tranexamic acid increase the risk of thromboembolism after bilateral simultaneous total knee arthroplasties in Asian Population? ( Kim, JS; Kim, YH; Park, JW; Seo, DH, 2018)
"The major concern with the use of tranexamic acid is that it may promote a hypercoagulable state and increase the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE), particularly when chemical thromboprophylaxis is not used."3.85Chemical Thromboprophylaxis Is Not Necessary to Reduce Risk of Thromboembolism With Tranexamic Acid After Total Hip Arthroplasty. ( Kim, JS; Kim, YH; Park, JW, 2017)
"Tranexamic acid (TXA) is a standard component of Tactical Combat Casualty Care."3.01A Systematic Review of Tranexamic Acid-Associated Venous Thromboembolic Events in Combat Casualties and Considerations for Prolonged Field Care. ( Ho, JW; Keeney-Bonthrone, TP; Lozano, R; Ruf, AC; Russo, RM; Strayve, D; Zakaluzny, SA, 2023)
"Anemia is one of the most common complications after hip fracture surgery."3.01Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. ( Augustinus, S; Gardenbroek, TJ; Goslings, JC; Mulders, MAM, 2023)
" The ongoing trials create six new comparisons: tranexamic acid (tablet + injection) versus placebo; intravenous tranexamic acid versus oral tranexamic acid; topical tranexamic acid versus oral tranexamic acid; different intravenous tranexamic acid dosing regimes; topical tranexamic acid versus topical fibrin glue; and fibrinogen (injection) versus placebo."3.01Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures. ( Brunskill, SJ; Champaneria, R; Dorée, C; Estcourt, LJ; Geneen, LJ; Gibbs, VN; Novak, A; Palmer, AJ; Raval, P, 2023)
"Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip or knee arthroplasty."3.01Efficacy and safety of single- and double-dose intravenous tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis. ( Cheng, QH; Guo, HZ; Yang, X; Yang, YZ; Zhang, AR; Zhang, ZZ, 2023)
"Elderly patients with intertrochanteric fractures exhibit post-traumatic hidden blood loss (HBL)."3.01Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial. ( Chen, X; He, T; Li, M; Liu, L; Liu, X; Long, X; Ma, H; Wang, H; Wang, W; Xu, Z, 2021)
"The primary outcome was postpartum hemorrhage, defined as a calculated estimated blood loss greater than 1000 ml or receipt of a red-cell transfusion within 2 days after delivery."3.01Tranexamic Acid for the Prevention of Blood Loss after Cesarean Delivery. ( Azria, E; Benard, A; Bohec, C; Bretelle, F; Chauleur, C; Daniel, V; Darsonval, A; de Marcillac, F; Deneux-Tharaux, C; Desbrière, R; Fuchs, F; Gallot, D; Gauchotte, E; Georget, A; Haddad, B; Kayem, G; Korb, D; Le Lous, M; Le Ray, C; Legendre, G; Letouzey, V; Madar, H; Mattuizzi, A; Mottet, N; Parant, O; Perrotin, F; Regueme, S; Roussillon, C; Rozenberg, P; Salomon, LJ; Sananès, N; Sénat, MV; Sentilhes, L; Vardon, D; Verspyck, E; Winer, N, 2021)
"Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98)."2.94Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. ( , 2020)
"Deep venous thrombosis (DVT) and pulmonary embolism (PE) events were monitored and recorded."2.94Combined use of intravenous and topical tranexamic acid efficiently reduces blood loss in patients aged over 60 operated with a 2-level lumbar fusion. ( Bai, T; Huang, Y; Li, J; Liu, Y; Wang, L, 2020)
"Tranexamic acid (TXA) has long been used to reduce blood loss associated with total knee arthroplasty (TKA)."2.90Comparison of oral vs. combined topical/intravenous/oral tranexamic acid in the prevention of blood loss in total knee arthroplasty: A randomised clinical trial. ( Bernaitis, N; Dare, W; King, L; Randle, R, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic drug."2.90Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels. ( Baaklini, LR; Cross, JR; Fields, KG; Jules-Elysee, KM; Mayman, DJ; McLawhorn, AS; Pickard, AJ; Qin, W; Sculco, TP; Su, EP; Tseng, A, 2019)
"No episodes of deep venous thrombosis or pulmonary embolism occurred in all cases."2.87Multiple-Dose Intravenous Tranexamic Acid Further Reduces Hidden Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial. ( Chen, G; Huang, Q; Huang, Z; Lei, Y; Pei, F; Xie, J, 2018)
"Only one patient in IV group exhibited deep venous thrombosis."2.87Tranexamic acid in primary total knee arthroplasty without tourniquet: a randomized, controlled trial of oral versus intravenous versus topical administration. ( Cao, C; Li, DH; Li, LL; Meng, WK; Pei, FX; Wang, D; Wang, HY; Zeng, WN; Zhou, ZK, 2018)
"No deep venous thrombosis or other severe complications had occurred."2.84Intra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial. ( Wang, J; Wang, Q; Zhang, X, 2017)
"The total blood loss and postoperative blood loss were significantly lower in groups B and C without any difference between them."2.84Efficacy of a Single Dose and an Additional Dose of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty. ( Cai, M; Ge, W; Li, S; Sun, Q; Wu, J; Yu, X, 2017)
"The optimal dosage and timing of tranexamic acid (TXA) in total knee arthroplasty (TKA) are undetermined."2.82Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial. ( Ma, J; Pei, F; Xie, J; Yao, H; Yue, C, 2016)
" The objective of this trial was to assess the efficacy and safety of intravenous (IV) administration combined with topical administration of TXA regarding postoperative blood loss and transfusion rates in patients treated with primary unilateral total hip arthroplasty."2.82Tranexamic Acid Administration in Primary Total Hip Arthroplasty: A Randomized Controlled Trial of Intravenous Combined with Topical Versus Single-Dose Intravenous Administration. ( Bin, S; Fuxing, P; Jing, Y; Pengde, K; Yi, Z; Zongke, Z, 2016)
" Moreover, TXA use is safe in terms of incidence of symptomatic DVT and TE."2.82Combined Administration of Systemic and Topical Tranexamic Acid for Total Knee Arthroplasty: Can It Be a Better Regimen and Yet Safe? A Randomized Controlled Trial. ( Jain, NP; Nisthane, PP; Shah, NA, 2016)
"Tranexamic acid was used to treat bleeding after spinal surgery."2.82Meta-Analysis of the Efficacy and Safety of Tranexamic Acid in Spinal Surgery. ( Bao, X; Chen, Y; Cheng, Q; Gao, Z; Lu, H; Wu, Z, 2022)
"Tranexamic acid can be effective at decreasing blood loss and transfusion requirements associated with total hip arthroplasty (THA), but few studies have compared the efficacy of different intravenous dosing regimes."2.82Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses. ( Kang, P; Ma, J; Pei, F; Wang, C; Xie, J; Yue, C, 2016)
"No pulmonary embolism was observed and no significant differences were found in other complications between the 2 groups."2.82The Efficacy and Safety of Combination of Intravenous and Topical Tranexamic Acid in Revision Hip Arthroplasty: A Randomized, Controlled Trial. ( Cao, F; Shen, B; Si, HB; Wu, YG; Yang, TM; Zeng, Y, 2016)
"No deep vein thrombosis was detected through Doppler ultrasound examination."2.80The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trial. ( Ding, PJ; Li, J; Lv, YM; Yang, Y; Ying-Ze, Z, 2015)
"No symptomatic deep vein thrombosis or pulmonary embolism was found in all patients."2.79Clinical value of tranexamic acid in unilateral and simultaneous bilateral TKAs under a contemporary blood-saving protocol: a randomized controlled trial. ( Chang, CB; Kang, YG; Kim, TK; Lee, JH; Lee, SH; Seo, ES; Yun, JH, 2014)
"No patient in either group developed deep vein thrombosis or pulmonary embolism up to 3 months."2.75Effects of tranexamic acid on blood loss during total hip arthroplasty. ( Ballal, MS; Denn, PG; Mitchell, P; Singh, J, 2010)
"Tranexamic acid is a fibrinolytic inhibitor which reduces blood loss in total knee replacement."2.74The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement. ( Ahmad, M; Biant, LC; Field, RE; Rajesparan, K, 2009)
"Oral tranexamic acid (TXA) has been demonstrated to reduce the blood loss in primary total knee and hip arthroplasty, but the optimal regimen of oral TXA administration is still unknown."2.66The optimal regimen of oral tranexamic acid administration for primary total knee/hip replacement: a meta-analysis and narrative review of a randomized controlled trial. ( Li, XL; Liu, WF; Liu, Y; Shao, J; Ye, W, 2020)
"Secondary outcomes were length of stay, deep venous thrombosis (DVT) and/or pulmonary embolism (PE)."2.61Transfusions and cost-benefit of oral versus intravenous tranexamic acid in primary total hip arthroplasty: A meta-analysis of randomized controlled trials. ( Chen, H; Ji, M; Liu, W; Tang, J; Wang, N; Xiong, X; Xu, L; Yang, T; Yang, Y, 2019)
"Tranexamic acid (TXA) is an anti-fibrinolytic agent successfully preventing blood loss when using intravenously (IV) in total hip arthroplasty (THA) and total knee arthroplasty (TKA)."2.58Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta-analysis. ( Gong, G; Han, N; Han, X; Liu, M, 2018)
"Tranexamic acid (TA) is a potent drug to reduce surgical blood loss in surgery, therefore, as a potential drug for application in THA."2.55Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials. ( Hu, Y; Lei, P; Su, W; Zeng, M; Zhu, J; Zhu, Y, 2017)
" Secondary outcomes were other adverse events, blood transfusion, and blood loss."2.55The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. ( Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C, 2017)
"Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty."2.53Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2016)
" To further investigate the safe and effective role of using tranexamic acid (TA) in reducing transfusion rate and blood loss in total knee arthroplasty."2.52Safety and Efficacy of Tranexamic Acid in Total Knee Arthroplasty. ( Li, W; Liu, J; Qiu, Y; Xu, P; Yu, X; Zhu, Y, 2015)
"Meanwhile TA is recommended to reduce deep vein thrombosis and pulmonary embolism following TKA."2.49Use of intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials. ( Chen, C; Fu, DJ; Guo, L; Yang, L, 2013)
"The meta-analysis shows that the use of tranexamic acid for patients undergoing total knee arthroplasty is effective and safe for the reduction of blood loss."2.48Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis. ( Chen, WP; Wu, LD; Yang, ZG, 2012)
" A total of 19 trials were eligible: 18 used intravenous administration, one also evaluated oral dosing and one trial evaluated topical use."2.47Tranexamic acid in total knee replacement: a systematic review and meta-analysis. ( Alshryda, S; Blenkinsopp, J; Mason, JM; Nargol, A; Sarda, P; Sukeik, M, 2011)
" To date, the most efficacious dosing protocol in this setting has not yet been ascertained."1.72No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA. ( Bugbee, WD; Copp, SN; Evans, AS; Ezzet, KA; McCauley, JC; Rosen, AS; Walker, RH; Wilde, JM, 2022)
"Tranexamic acid (TXA) has been shown to reduce blood loss and postoperative transfusions in total knee arthroplasty (TKA)."1.62One Versus Two Doses of Intravenous Tranexamic Acid in Total Knee Arthroplasty. ( Bernstein, JA; Charette, RS; Kamath, AF; Nchako, CM; Nelson, CL; Sloan, M, 2021)
"The incidence of deep vein thrombosis in the topical group (1."1.51Comparison of three routes of administration of tranexamic acid in primary unilateral total knee arthroplasty: Analysis of a national database. ( Hu, Q; Huang, Z; Pei, F; Xie, J; Zhou, Z, 2019)
"This study demonstrated that intra-articular 1 g TXA administration during TKA is safe and effective for reducing blood loss and blood transfusion without increasing VTE risk."1.51Intra-articular 1 g tranexamic acid administration during total knee arthroplasty is safe and effective for the reduction of blood loss and blood transfusion. ( Furumatsu, T; Hino, T; Kamatsuki, Y; Kodama, Y; Masuda, S; Miyazawa, S; Okazaki, Y; Ozaki, T, 2019)
"Tranexamic acid (TXA) has been shown to significantly reduce transfusion rates in primary total hip arthroplasties (THAs), but high-quality evidence is limited in the revision setting."1.51Intravenous tranexamic acid safely and effectively reduces transfusion rates in revision total hip arthroplasty. ( Abdel, MP; Amundson, AW; Hernandez, NM; Hines, JT; Pagnano, MW; Sierra, RJ, 2019)
"Tranexamic acid was administered during 62% of the arthroplasties in the ATT+ group and to 90% in the ATT- group."1.48Tranexamic acid use and risk of thrombosis in regular users ofantithrombotics undergoing primary total knee arthroplasty: a prospectivecohort study. ( Fennema, P; Hourlier, H, 2018)
"Tranexamic acid was not used perioperatively."1.46Prevalence of Venous Thromboembolic Events Is Low in Asians After Total Knee Arthroplasty Without Chemoprophylaxis. ( Bin Abd Razak, HR; Binte Abd Razak, NF; Tan, HA, 2017)
"VTE recurrence was not significantly greater in those who received TXA (2."1.46Tranexamic Acid Was Safe in Arthroplasty Patients With a History of Venous Thromboembolism: A Matched Outcome Study. ( Abdel, MP; Amundson, AW; Larson, DR; Pagnano, MW; Sabbag, OD, 2017)
"For the TXA+ group, 0."1.46Low Risk of Thromboembolic Events After Routine Administration of Tranexamic Acid in Hip and Knee Arthroplasty. ( Husted, H; Kallemose, T; Madsen, RV; Nielsen, CS; Troelsen, A, 2017)
"Melasma is a common pigmentary disorder among Asians and treatment is challenging."1.43Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis. ( Goh, CL; Lee, HC; Thng, TG, 2016)
"There were no deep venous thrombosis or thromboembolic complications in any group."1.43A comparative, retrospective study of peri-articular and intra-articular injection of tranexamic acid for the management of postoperative blood loss after total knee arthroplasty. ( Dai, K; Mao, Z; Wang, Y; Yan, M; Yue, B, 2016)
"Tranexamic acid (TXA) is an antifibrinolytic that reduces blood loss after THA and TKA."1.43Balancing Thromboprophylaxis and Bleeding in Total Joint Arthroplasty: Impact of Eliminating Enoxaparin and Predonation and Implementing Pneumatic Compression and Tranexamic Acid. ( Campbell, JC; Mirocha, JM; Sharfman, ZT; Spitzer, AI, 2016)
"The incidence of symptomatic deep vein thrombosis and pulmonary embolism was evaluated."1.43Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis. ( Chen, AF; Heller, S; Parvizi, J; Secrist, E; Shahi, A, 2016)
"Tranexamic acid (TXA) has been used to reduce blood loss during total hip arthroplasty (THA), but its use could increase the risk of venous thromboembolic disease (VTE)."1.42Does tranexamic acid alter the risk of thromboembolism after total hip arthroplasty in the absence of routine chemical thromboprophylaxis? ( Hamada, M; Nishihara, S, 2015)
"Tranexamic acid (TXA) has shown safety and efficacy in reducing blood loss associated with various surgical procedures."1.42Does Tranexamic Acid Reduce Blood Loss and Transfusion Requirements Associated With the Periacetabular Osteotomy? ( Baca, GR; Clohisy, JC; Keith, AD; Schoenecker, PL; Wingerter, SA, 2015)
"Tranexamic acid (TXA) is an antifibrinolytic agent that competitively inhibits the activation of plasminogen to plasmin."1.42Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty. ( George, DA; Nwaboku, H; Sarraf, KM, 2015)
"Tranexamic acid was effective in reducing the need for blood transfusions while not increasing the risk of complications, including thromboembolic events and renal failure."1.40Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. ( Boettner, F; Danninger, T; Mazumdar, M; Memtsoudis, SG; Opperer, M; Poeran, J; Rasul, R; Suzuki, S, 2014)

Research

Studies (115)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (7.83)29.6817
2010's82 (71.30)24.3611
2020's24 (20.87)2.80

Authors

AuthorsStudies
Chang, MJ1
Shin, JY1
Yoon, C1
Kim, TW1
Chang, CB3
Kang, SB1
Wilde, JM1
Copp, SN1
Ezzet, KA1
Rosen, AS1
Walker, RH1
McCauley, JC1
Evans, AS1
Bugbee, WD1
Qu, W1
Zhou, H1
Tian, P2
Qin, X1
Zhang, Y2
Shen, W1
Zhang, D1
Wu, X2
Kong, Q1
Wang, Y3
Zhang, B1
Feng, P1
Wu, Y3
Guo, C1
Li, W3
Bao, X1
Lu, H1
Gao, Z2
Wu, Z1
Chen, Y3
Cheng, Q1
Qi, MT1
Wang, SY1
Wang, LT1
Chen, XW1
Zhan, WH1
Zhu, XF1
Wang, H3
Russo, RM1
Lozano, R1
Ruf, AC1
Ho, JW1
Strayve, D1
Zakaluzny, SA1
Keeney-Bonthrone, TP1
Augustinus, S2
Mulders, MAM2
Gardenbroek, TJ2
Goslings, JC2
Joo, YB1
Kim, YM1
An, BK1
Lee, CW1
Kwon, ST1
Song, JH1
Luan, H1
Liu, K1
Peng, C1
Tian, Q1
Song, X1
Zheng, C1
Ma, J4
Xu, J1
Li, M2
Wu, L1
Liu, Y5
Shen, B3
Xiao, C1
Yu, W1
Yao, K1
Cao, Y1
Long, N1
Zhang, S1
Jiang, Y1
Gibbs, VN1
Geneen, LJ1
Champaneria, R1
Raval, P1
Dorée, C1
Brunskill, SJ1
Novak, A1
Palmer, AJ1
Estcourt, LJ1
Yang, YZ1
Cheng, QH1
Zhang, AR1
Yang, X1
Zhang, ZZ1
Guo, HZ1
Knowlton, LM1
Arnow, K1
Trickey, AW1
Sauaia, A1
Knudson, MM1
Zhang, Q1
Zhao, L1
Yu, Z1
Guo, JJ1
King, L1
Randle, R1
Dare, W1
Bernaitis, N1
Gerstein, NS1
Cushnyr, BW1
Petersen, TR1
Siegel, D1
Charette, RS1
Bernstein, JA1
Sloan, M1
Nchako, CM1
Kamath, AF1
Nelson, CL1
Jules-Elysee, KM1
Tseng, A1
Sculco, TP1
Baaklini, LR1
McLawhorn, AS1
Pickard, AJ1
Qin, W1
Cross, JR1
Su, EP1
Fields, KG1
Mayman, DJ1
Li, J2
Wang, L1
Bai, T1
Huang, Y1
Yang, L2
Jia, X1
Yang, J1
Kang, J1
Ye, W1
Liu, WF1
Li, XL1
Shao, J1
Sun, C1
Zhang, X3
Chen, L1
Deng, J1
Ma, Q1
Cai, X1
Yang, H1
Ma, H1
Long, X1
Xu, Z1
Chen, X3
He, T1
Wang, W2
Liu, L1
Liu, X1
Sentilhes, L1
Sénat, MV1
Le Lous, M1
Winer, N1
Rozenberg, P1
Kayem, G1
Verspyck, E1
Fuchs, F1
Azria, E1
Gallot, D1
Korb, D1
Desbrière, R1
Le Ray, C1
Chauleur, C1
de Marcillac, F1
Perrotin, F1
Parant, O1
Salomon, LJ1
Gauchotte, E1
Bretelle, F1
Sananès, N1
Bohec, C1
Mottet, N1
Legendre, G1
Letouzey, V1
Haddad, B1
Vardon, D1
Madar, H1
Mattuizzi, A1
Daniel, V1
Regueme, S1
Roussillon, C1
Benard, A1
Georget, A1
Darsonval, A1
Deneux-Tharaux, C1
Montroy, J1
Fergusson, NA1
Hutton, B1
Lavallée, LT1
Morash, C1
Cagiannos, I1
Cnossen, S1
Fergusson, DA1
Breau, RH1
Liu, WB1
Li, ZJ1
Xu, GJ2
Huang, YT1
Ma, XL2
Wang, J3
Wang, Q4
Dai, WL1
Zhou, AG1
Zhang, H1
Zhang, J1
Yozawa, S1
Ogawa, H1
Matsumoto, K1
Akiyama, H1
Wang, Z1
Shen, X1
Kim, YH3
Park, JW3
Kim, JS3
Seo, DH1
Zhu, J1
Zhu, Y2
Lei, P1
Zeng, M1
Su, W1
Hu, Y1
Liao, L1
Tang, Q1
Chen, YY1
Wang, WC1
Tian, S1
Shen, Z1
Peng, A1
Liu, Q1
Geng, P1
Shi, L1
Wang, P1
Lei, Y1
Huang, Q1
Huang, Z3
Xie, J5
Chen, G1
Pei, F5
Palanisamy, JV1
Das, S1
Moon, KH1
Kim, DH1
Kim, TK3
Fraval, A1
Duncan, S1
Murray, T1
Duggan, J1
Tirosh, O1
Tran, P1
Xiong, H1
Zeng, Y2
Wang, D1
Wang, HY1
Cao, C1
Li, LL1
Meng, WK1
Pei, FX1
Li, DH1
Zhou, ZK1
Zeng, WN1
Pandey, K1
Myers, SP1
Kutcher, ME1
Rosengart, MR1
Sperry, JL1
Peitzman, AB1
Brown, JB1
Neal, MD1
Hu, Q1
Zhou, Z2
Han, X1
Gong, G1
Han, N1
Liu, M2
Yu, CC1
Kadri, O1
Kadado, A1
Buraimoh, M1
Pawloski, J1
Bartol, S1
Graziano, G1
Dibiasi, C1
Wiegele, M1
Gratz, J1
Wang, N1
Xiong, X1
Xu, L1
Ji, M1
Yang, T1
Tang, J1
Yang, Y2
Liu, W1
Chen, H1
Zheng, F1
Zheng, Z1
Wu, C1
Hines, JT1
Hernandez, NM1
Amundson, AW2
Pagnano, MW2
Sierra, RJ1
Abdel, MP2
Kamatsuki, Y1
Miyazawa, S1
Furumatsu, T1
Kodama, Y1
Hino, T1
Okazaki, Y2
Masuda, S1
Ozaki, T1
Fu, DJ1
Chen, C1
Guo, L1
Koh, IJ1
Kang, YG1
Seo, ES1
Lee, JH1
Yun, JH1
Lee, SH1
Georgiadis, AG1
Muh, SJ1
Silverton, CD1
Weir, RM1
Laker, MW1
Huang, F1
Wu, D1
Ma, G1
Yin, Z1
Chen, JY2
Rikhraj, IS1
Tay, DK2
Chin, PL2
Chia, SL2
Lo, NN2
Yeo, SJ2
George, DA1
Sarraf, KM1
Nwaboku, H1
Lv, YM1
Ding, PJ1
Ying-Ze, Z1
Alshryda, S2
Sukeik, M2
Sarda, P2
Blenkinsopp, J2
Haddad, FS1
Mason, JM2
Poeran, J1
Rasul, R1
Suzuki, S1
Danninger, T1
Mazumdar, M1
Opperer, M1
Boettner, F1
Memtsoudis, SG1
Wang, C2
Han, Z1
Ma, JX1
Jiang, X1
Xie, S1
Wang, K1
Nishihara, S1
Hamada, M1
Yue, C3
Yang, P1
Kang, P2
Wingerter, SA1
Keith, AD1
Schoenecker, PL1
Baca, GR1
Clohisy, JC1
Wei, Z1
Zhang, W1
Bai, G1
Zhang, C1
Lin, J1
Yu, X2
Xu, P1
Liu, J1
Qiu, Y1
Jain, NP1
Nisthane, PP1
Shah, NA1
Sharfman, ZT1
Campbell, JC1
Mirocha, JM1
Spitzer, AI1
Chen, S1
Wu, K1
Kong, G1
Feng, W1
Deng, Z1
Heller, S1
Secrist, E1
Shahi, A1
Chen, AF1
Parvizi, J1
Sargant, N1
Roy, A1
Simpson, S1
Chandrakumaran, K1
Alves, S1
Coakes, J1
Bell, J1
Knight, J1
Wilson, P1
Mohamed, F1
Cecil, T1
Moran, B1
Stowers, MD1
Munro, JT1
Hill, AG1
Wu, YG1
Yang, TM1
Si, HB1
Cao, F1
Lee, HC1
Thng, TG1
Goh, CL1
Moskal, JT1
Capps, SG1
Yao, H1
Sun, X1
Dong, Q1
Zhang, YG1
Yi, Z1
Bin, S1
Jing, Y1
Zongke, Z1
Pengde, K1
Fuxing, P1
Gao, F1
Sun, W1
Guo, W1
Li, Z1
Shin, YS1
Yoon, JR1
Lee, HN1
Park, SH2
Lee, DH1
Pinsornsak, P1
Rojanavijitkul, S1
Chumchuen, S1
Wang, JW1
Chen, B1
Lin, PC1
Yen, SH1
Huang, CC1
Kuo, FC1
Weng, K1
Bi, Q1
Zhao, C1
Hourlier, H1
Fennema, P1
Mao, Z1
Yue, B1
Yan, M1
Dai, K1
Bin Abd Razak, HR1
Binte Abd Razak, NF1
Tan, HA1
Madsen, RV1
Nielsen, CS1
Kallemose, T1
Husted, H1
Troelsen, A1
Sun, Q1
Wu, J1
Ge, W1
Cai, M1
Li, S1
Zhang, XQ1
Ni, J1
Ge, WH1
Zhang, P2
Liang, Y2
Chen, P2
Fang, Y2
He, J2
Sabbag, OD1
Larson, DR1
Ghosh, K2
Escher, R1
Rajesparan, K1
Biant, LC1
Ahmad, M1
Field, RE1
Madrid, C1
Sanz, M1
Singh, J1
Ballal, MS1
Mitchell, P1
Denn, PG1
Onodera, T1
Majima, T1
Sawaguchi, N1
Kasahara, Y1
Ishigaki, T1
Minami, A1
Kerros, H1
Roule, V1
Ivascau, C1
Labombarda, F1
Nargol, A1
Mihalache, RM1
Ames, PR1
Yang, ZG1
Chen, WP1
Wu, LD1
Seo, JG1
Moon, YW1
Kim, SM1
Ko, KR1
Zohar, E1
Ellis, M1
Ifrach, N1
Stern, A1
Sapir, O1
Fredman, B1
Huvers, F1
Slappendel, R1
Benraad, B1
van Hellemondt, G1
van Kraaij, M1
Orpen, NM1
Little, C1
Walker, G1
Crawfurd, EJ1
Molenaar, IQ1
Warnaar, N1
Groen, H1
Tenvergert, EM1
Slooff, MJ1
Porte, RJ1
Berntorp, E1
Follrud, C1
Lethagen, S1

Clinical Trials (50)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective, Multicenter, Randomized, Parallel Groups Study Comparing the Safety and the Efficacy of the Administration of One Intra-articular Injection of 4.8 ml (HO-1) or Three Intra-articular Injections of 2.2 ml (HS-3) of Pandora Gel to One Intra-arti[NCT05978180]252 participants (Anticipated)Interventional2023-10-18Recruiting
Prospective, Multicenter, Open Study Evaluating the Short-term Safety of Use of Pandora Administered in the Form of 1 Intra-articular Injection of Happyone or 3 Intra-articular Injections of Happysoft in Patients Suffering From Gonarthrosis[NCT05414617]20 participants (Actual)Interventional2022-06-08Completed
Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage[NCT05554211]Phase 230 participants (Anticipated)Interventional2022-07-12Recruiting
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321]60 participants (Actual)Interventional2022-03-24Completed
Tranexamic Acid for the Treatment of Gastrointestinal Haemorrhage: an International Randomised, Double Blind Placebo Controlled Trial[NCT01658124]Phase 312,009 participants (Actual)Interventional2013-07-31Completed
TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery :a Multicenter Randomised, Double Blind Placebo Controlled Trial (TRAAP2)[NCT03431805]Phase 34,574 participants (Actual)Interventional2018-03-03Completed
Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid: a Clinical Trial[NCT03915756]42 participants (Anticipated)Interventional2019-08-22Recruiting
The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures.[NCT04488367]Early Phase 1120 participants (Anticipated)Interventional2020-07-06Recruiting
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss, Transfusion Index and Complications After Total Hip Replacement. A Prospective, Randomized, Double Blind Clinical Trial[NCT04187014]Phase 290 participants (Actual)Interventional2020-02-06Completed
Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy[NCT03954860]80 participants (Actual)Interventional2018-08-01Completed
Evaluation of the Use of Tranexamic Acid in Tibial Osteotomies: a Randomised Controlled Clinical Trial.[NCT04785651]84 participants (Anticipated)Interventional2021-02-22Recruiting
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty[NCT03825939]Phase 452 participants (Actual)Interventional2015-04-21Terminated (stopped due to Lack of patient enrollment due to only one surgeon that was enrolling.)
Single Centre Randomised Controlled Trial to Assess the Effect of the Addition of Twenty-four Hours of Oral Tranexamic Acid Post-operatively to a Single Intra-operative Intravenous Dose of Tranexamic Acid on Calculated Blood Loss Following Primary Hip and[NCT03690037]Phase 41,089 participants (Actual)Interventional2016-07-07Completed
Comparison of the Effect of Two Common Regimens of Administration of Tranexamic Acid on Hemostasis and Clinical Outcome of Patients Undergoing Total Knee Arthroplasty[NCT04443920]Phase 486 participants (Actual)Interventional2019-10-29Completed
Comparison of Combined Topical Tranexamic Acid With Floseal® With Intravenous Tranexamic Acid on Blood Loss in Total Knee Arthroplasty[NCT03328832]Phase 470 participants (Actual)Interventional2017-09-12Completed
Blood Loss Reduction After Total Knee Arthroplasty. A Comparison Between Topical Tranexamic Acid and Platelet Rich Plasma: Controlled Clinical Trial[NCT02650856]Phase 340 participants (Actual)Interventional2015-09-30Completed
Blood-saving Effect of Kaolin-based Hemostatic Gauze Combined With Intravenous Tranexamic Acid in Total Knee Arthroplasty[NCT05504577]Phase 4120 participants (Anticipated)Interventional2022-03-16Recruiting
Comparison of Topical and Infusion Tranexamic Acid on Blood Loss and Risk of Deep Vein Thrombosis After Total Knee Arthroplasty[NCT02453802]Phase 490 participants (Anticipated)Interventional2015-06-30Not yet recruiting
Comparison of Topical Tranexamic Acid and Floseal® on Blood Loss After Total Knee Arthroplasty in Patients With a Thromboembolic Risk[NCT02865174]Phase 490 participants (Anticipated)Interventional2016-09-30Not yet recruiting
The Use of Tranexamic Acid in Irrigation Fluid to Improve Arthroscopic Visualization in Shoulder Surgery: A Randomized Controlled Trial[NCT04594408]Phase 4128 participants (Actual)Interventional2020-09-01Active, not recruiting
Prophylactic Use of Topical Tranexamic Acid to Aid Surgical Haemostasis During Caesarean Sections in Parturients With Moderate to High Risk of Bleeding[NCT02492087]Phase 384 participants (Anticipated)Interventional2015-08-31Recruiting
The Use of Tranexamic Acid to Reduce the Need for Transfusion 1 Week Post-operatively for Hemiarthroplasty or Intramedullary Nailing Needed to Correct Acute Hip Fractures[NCT02947529]Phase 4113 participants (Actual)Interventional2015-08-31Completed
Prospective Randomized Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty[NCT03359525]Phase 4114 participants (Anticipated)Interventional2017-07-01Recruiting
The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816]25 participants (Actual)Interventional2016-04-30Terminated (stopped due to Study enrollment and goals unable to be reached.)
Local Injection of Tranexamic Acid May Reduce Bleeding, Injection Pain, and Other Post-op Complications During Mohs Micrographic Surgery[NCT04630886]Early Phase 1200 participants (Anticipated)Interventional2021-06-16Enrolling by invitation
The Effectiveness Of Intravenous Tranexamic Acid (TXA) on Reducing Perioperative Blood Loss For Patients Undergoing Periacetabular Osteotomy (PAO): A Randomized Double Blind Placebo Controlled Trial[NCT03823417]Phase 40 participants (Actual)Interventional2019-07-31Withdrawn (stopped due to Investigators decided not to begin the study.)
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean Delivery: A Randomized Controlled Trial[NCT03364491]Phase 311,000 participants (Actual)Interventional2018-03-15Completed
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty: A Prospective, Double-Blind Randomized, Controlled Trial[NCT03074994]Phase 2108 participants (Anticipated)Interventional2016-10-31Recruiting
Efficacy of Tranexamic Acid in Femoral Shaft Fractures Osteosynthesis; A Double Blind Randomized Controlled Trial[NCT04803591]Phase 40 participants (Actual)Interventional2021-08-01Withdrawn (stopped due to Not approved by Ethics Commettee)
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application, a Comparison With Intravenous Tranexamic Acid Only in Total Hip Arthroplasty[NCT03623789]Phase 490 participants (Anticipated)Interventional2018-08-15Recruiting
The Efficacy of Tranexamic Acid in the Treatment of Lichen Planus Pigmentosus and Erythema Dyschromicum Perstans[NCT04233749]Phase 25 participants (Anticipated)Interventional2020-03-17Recruiting
Tissue-resident Memory T Cells Expression in Melasma[NCT05698342]20 participants (Actual)Observational2021-07-01Completed
Do Peri-operative High Doses of Intravenous Glucocorticoids Improve Short-term Functional Outcome After Direct Anterior Total Hip Arthroplasty? A Randomized, Single Surgeon, Placebo Controlled, Double Blind Study[NCT04317872]70 participants (Anticipated)Interventional2020-07-01Recruiting
Peri-articular Tranexamic Acid Injection in Total Knee Arthroplasty: A Randomized Controlled Trial[NCT02829346]Phase 260 participants (Actual)Interventional2012-10-31Completed
TRACE STUDY: A Randomized Controlled Trial Using Tranexamic Acid in the Treatment of Subdural Hematoma[NCT05713630]Phase 3130 participants (Anticipated)Interventional2024-03-31Not yet recruiting
Role of Topical Tranexamic Acid in Total Hip Arthroplasty[NCT01866943]Phase 241 participants (Actual)Interventional2011-11-30Terminated
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
Evaluation of Tranexamic Acid Prior to Surgery in the Geriatric Hip Fracture Population for the Reduction of Post-Operative Blood Transfusion[NCT03923959]Phase 3400 participants (Anticipated)Interventional2020-02-01Active, not recruiting
Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study[NCT04846114]71 participants (Actual)Interventional2016-03-31Completed
Evaluation of Efficacy and Safety of Perioperative Tranexamic Acid During Primary Total Knee Arthroplasty: A Randomized, Clinical Trial[NCT05919615]100 participants (Actual)Interventional2021-07-15Completed
Intravenous Tranexamic Acid to Reduce Blood Loss in Reverse Total Shoulder Arthroplasty[NCT02043132]Phase 2/Phase 3116 participants (Actual)Interventional2013-09-30Completed
Serial Use of Intravenous and Oral Tranexamic Acid in Primary Total Knee Arthroplasty Patients: A Randomized Controlled Study[NCT03109652]Phase 4144 participants (Anticipated)Interventional2017-07-10Recruiting
Tranexamic Acid in Knee Joint Surgery - a Randomised Controlled Trial[NCT02278263]Phase 4150 participants (Actual)Interventional2014-12-31Completed
Investigation of the Blood Sparing Properties of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty[NCT02569658]110 participants (Actual)Interventional2015-09-30Completed
The Combined Efficacy of Evicel and Tranexamic Acid on Total Knee Arthroplasty During the Early Perioperative Period[NCT02553122]Phase 30 participants (Actual)Interventional2015-10-31Withdrawn (stopped due to Data has been published on this study (this would have been a duplicate study))
Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103]30 participants (Actual)Interventional2018-02-02Completed
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement; A Prospective Triple-blinded Randomized Controlled Trial.[NCT01850394]152 participants (Actual)Interventional2010-01-31Completed
IV Tranexamic Acid Prior to Hysterectomy for Reduction of Intraoperative Blood Loss: A Randomized Placebo-Controlled Trial[NCT02911831]Early Phase 171 participants (Actual)Interventional2016-11-30Completed
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma. A Double-blind, Placebo-controlled, Multicentre, Randomized Controlled Clinical Trial[NCT03582293]Phase 3140 participants (Anticipated)Interventional2018-06-19Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Hospital Stay

Measured in Days (NCT03825939)
Timeframe: At Hospital Discharge

InterventionDays (Mean)
Intravenous Tranexamic Acid3
Intravenous Placebo3
Intravenous Tranexamic Acid Followed by Intravenous Placebo3

Blood Transfusion Rate

We will record the event of blood transfusion, and calculate the incidence of transfusion (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4

InterventionParticipants (Count of Participants)
Combined Topical TXA and Floseal1
Topical TXA Alone0

Incidence of Thrombosis Events

The composite of any venous thromoembolism events, ischemic heart attacks, cerebrovascular accidents (NCT03328832)
Timeframe: within 30 days of the operation

InterventionParticipants (Count of Participants)
Combined Topical TXA and Floseal0
Topical TXA Alone0

Total Blood Loss After Operation

Total blood loss was calculated according to Nadler et al., which used maximum postoperative reduction of the Hb level adjust for weight and height of the patient. The formula is as follows, Total blood loss = (Total blood volume x [change in Hb level / preoperative Hb level])x1000+volume transfused (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4

Interventionml (Mean)
Combined Topical TXA and Floseal678
Topical TXA Alone733

Therapeutic Effect on Drainage Quantification

The blood quantification will be taken at 6am every day. (NCT02650856)
Timeframe: up to 2nd day post operative (24 and 48 hrs)

,
InterventionmL (Mean)
24 hours48 hours
Group 1 Tranexamic Acid246.4120.8
Group 2 Platelet Rich Plasma263.2140.2

Therapeutic Effect on Hematocrit Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventionpercentage of Hematocrite (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid41.731.629.128.6
Group 2 Platelet Rich Plasma41.529.827.727.3

Therapeutic Effect on Hemoglobin Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventiong/dL (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid13.610.39.59.3
Group 2 Platelet Rich Plasma13.69.99.29.1

Blood Transfusion Rates, Defined Nominally (Binary) as Having at Least One Transfusion

To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge

InterventionPatients with 1 or more transfusions (Number)
Tranexamic Acid2
Placebo3

Effect of Tranexamic Acid on the Total Length of Hospital Admission for a Large (350 cm2) Burn Injury

To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge

InterventionDays (Median)
Tranexamic Acid23
Placebo9

Intraoperative Blood Loss in mL

To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes

InterventionmL (Median)
Tranexamic Acid100
Placebo325

Change in Hemoglobin

[Key secondary outcome] Change in hemoglobin from the most recent measured before delivery to lowest measured in the 48 hours after delivery (NCT03364491)
Timeframe: from 4 weeks before delivery to 48 hours postpartum

Interventiongrams per deciliter (Mean)
Tranexamic Acid-1.8
Placebo-1.9

Length of Stay

Mother's length of stay from delivery to discharge (NCT03364491)
Timeframe: Until hospital discharge, an average of 3 days

Interventiondays (Median)
Tranexamic Acid3
Placebo3

Number of Mothers Who Died or Had Thromboembolic Events (Venous or Arterial), Ischemic Stroke, Myocardial Infarction, New-onset Seizure Activity, or Were Admitted to the Intensive Care Unit for More Than 24 Hours

(NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid35
Placebo32

Number of Participants Who Received Open Label TXA or Other Antifibrinolytic

This is the number of mothers who were treated with any amount of open-label TXA (not blinded study drug) or another antifibrinolytic (eg., Amicar) (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid108
Placebo109

Number of Participants Who Received Surgical or Radiologic Interventions to Control Bleeding and Related Complications

This is the number of mothers who required any of the following types of surgical procedures to control bleeding: laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid233
Placebo231

Number of Participants Who Received Treatments and Interventions in Response to Bleeding and Related Complications

[Key secondary outcome] This is the number of mothers who received treatments and interventions to control bleeding such as: uterotonics such as prostaglandins or methergine, but excluding oxytocin; open label TXA or other antifibrinolytics; transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets or administration of any factor concentrates; laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid892
Placebo986

Number of Participants Who Were Transfused With 4 or More Units of Packed Red Blood Cells

Participants were categorized according to the amount of packed red blood cells or whole blood transfused, either as 0 to 3 units, or 4 or more units (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid20
Placebo19

Number of Participants Who Were Transfused With Other Blood Products

This is the number of mothers who received during the first 7 days after delivery a transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets, or received any factor concentrates (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid29
Placebo31

Number of Participants Who Were Treated With Uterotonics Other Than Oxytocin

This is the number of mothers who were treated with uterotonics such as prostaglandins or methergine, but excluding oxytocin, from delivery through 48 hours after delivery. (NCT03364491)
Timeframe: within 48 hours postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid649
Placebo732

Number of Participants With a Thromboembolic Event (Venous or Arterial), Ischemic Stroke, or Myocardial Infarction

[Key secondary outcome] This is the number of mothers who experienced a thromboembolic event, ischemic stroke, or myocardial infarction during the 6 weeks after delivery. (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid12
Placebo13

Number of Participants With Estimated Blood Loss Greater Than 1 Liter During Delivery

[Major secondary outcome] The surgeon or anesthesiologist estimated the blood loss during the delivery in milliliters, which was recorded in the anesthesia record and/or operative report (NCT03364491)
Timeframe: From skin incision to transfer from operating room, average of 1 hour

InterventionParticipants (Count of Participants)
Tranexamic Acid339
Placebo368

Number of Participants With Maternal Death or Transfusion of Packed Red Blood Cells

Participants were monitored from delivery until hospital discharge or 7 days after delivery (postpartum), whichever is sooner. This is the number of mothers who died for any reason, or had a blood transfusion of 1 or more units (of packed red blood cells, including whole blood or cell saver). (NCT03364491)
Timeframe: by hospital discharge or by 7 days postpartum, whichever is sooner

InterventionParticipants (Count of Participants)
Tranexamic Acid201
Placebo233

Number of Participants With Postpartum Infectious Complications

[Key Secondary Outcome] This is the number of mothers who experienced any of the following infectious complications in the 6 weeks after delivery: endometritis, surgical site infection, pelvic abscess (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid162
Placebo125

Number of Participants With Seizure Activity That Was Not Seen Prior to Study Enrollment

This is the number of mothers who experienced seizure activity, confirmed by central review, whose onset is after enrollment (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid2
Placebo0

Estimated Blood Loss

Estimated Blood Loss defined as Pre Op Hgb mins the Post Op Day two Hgb. (NCT01866943)
Timeframe: Pre Op, Post Op Day 2

InterventionHemoglobin (grams/deciliter) (Mean)
Baseline Population2.93

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 2 week

Interventionunits on a scale (Mean)
All Study Participants65.76

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 6 week

Interventionunits on a scale (Mean)
All Study Participants81.77

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: Preoperative

Interventionunits on a scale (Mean)
All Study Participants58.34

Mid Thigh Circumference

Measurement of the thigh at the half way point between the prominence of the greater trochanter and the lateral epicondyle of the femur. No data recorded at 2 weeks or 6 weeks for this study population. (NCT01866943)
Timeframe: Pre Op

Interventioncentimeters (Mean)
Baseline Population52.99

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Number of Participants Experiencing Deep Vein Thrombosis

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Deep venous thrombosis" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Hematoma as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Hematoma" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Infection as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Infection" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Myocardial Infarction

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Myocardial infarction" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline1

Number of Participants Experiencing Pulmonary Embolism

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Pulmonary Embolism" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Total Blood Loss

Total Blood Loss as calculated according to method as described by Good et al. Total Blood Loss (mL) = 1000 X Hb(loss)/Hb(initial) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

InterventionTotal Blood Loss (mL) (Mean)
Tranexamic Acid1122.4
Normal Saline1472

Total Drain Output

Total Drain Output as measured postoperatively 0-48 hours (NCT02043132)
Timeframe: 0-48 hours postoperatively

InterventionmL (Mean)
Tranexamic Acid221
Normal Saline372

Total Hemoglobin Loss

Total hemoglobin loss estimated using the formula for total blood volume described by Nadler et al Hb(loss) = blood volume (L) x [Hb(initial)(g/L) - Hb(final)(g/L)] + Hb(transfused) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

Interventiong (Mean)
Tranexamic Acid154.6
Normal Saline200.1

Blood Loss

"The loss of haemoglobin (Hb) was then estimated according to the formula:~Hb(loss) = Blood volume (BV) x (Hbi-Hbe) x 0.001+Hbt~where Hb (loss) (g) is the amount of Hb lost, Hbi (g/L) the Hb concentration before surgery, Hbe (g/L) is the Hbe concentration on the third day after surgery, and Hbt (g) is the total amount of allogeneic Hb transfused. A unit of banked blood is considered to contain a minimum of 40g Hb (Blood component data sheet, New Zealand Blood Services [NZBS]). All units of blood are processed and stored in a nationally standardised manner. The blood loss (ml) was related to the patient's preoperative Hb value (g/L):~Blood loss =1000 x Hb(loss) /Hbi" (NCT02278263)
Timeframe: Post operative day 3

Interventionmls (Mean)
Control1090
Intraarticular716
Systemic746

Length of Stay (LOS)

Day of surgery is counted as Day 0. (NCT02278263)
Timeframe: Average length of stay is expected to be 3 to 5 days

Interventiondays (Median)
Control4
Topical4
Systemic4

Number of Participants Receiving Allogenic Blood Transfusion

"Those patients receiving blood products. Standardised protocol is as follows:~The criterion for transfusion of blood products will be a haemoglobin < 80g/L or a haemoglobin <100g/L in a patient with ischaemic heart disease or with significant symptomatology" (NCT02278263)
Timeframe: Participants will be followed for the duration of their hospital stay expected to be an average of 3-5 days

InterventionParticipants (Count of Participants)
Control2
Topical1
Systemic0

Perioperative Fluid Administration

Intravenous fluid (excluding blood transfusion) given during and first 24 hours after surgery (NCT02278263)
Timeframe: Day 1

Interventionmls (Mean)
Control1765
Topical1613
Systemic1807

Number of Participants Experiencing Symptomatic Venothromboembolic (VTE) Disease

Rates of deep vein thrombosis (DVT) and pulmonary embolus (PE) in each group recorded as a percentage (NCT02278263)
Timeframe: Postoperatively within 30 days after surgery

,,
InterventionParticipants (Count of Participants)
DVTPE
Control00
Systemic01
Topical02

Range of Active Flexion

Range of motion measured in degrees on postoperative days 1-3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control577175
Systemic587278
Topical657582

Range of Passive Flexion

Range of motion measured in degrees for postoperative days 1 to 3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control657682
Systemic688087
Topical748187

Number of Participants With Deep Vein Thrombosis

Must be diagnosed via ultrasound duplex (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group1

Number of Participants With Pulmonary Embolism

Must be diagnosed via CT chest or V/Q lung scan (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Participants With Stroke

Must be diagnosed via CT scan or MRI (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Patients Transfused

Patients who received a post-op transfusion of pack red blood cells (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Units Transfused

Units of pack red blood cells that the patients recieved (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionUnits of PRBCs (Number)
Tranexamic Acid Group0
Placebo Group0

Post-operative Blood Loss

Equated based on the patient's predicted blood volume and change in hemoglobin from the pre-operative level to the lowest post-operative level. (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionmL (Mean)
Tranexamic Acid Group152.2
Placebo Group178.0

Number of Patients Required Blood Transfusion

(NCT01850394)
Timeframe: postoperative period (5 days after surgery)

Interventionparticipants (Number)
Control Group10
TXA-250 Group6
TXA-500 Group0

Total Hemoglobin Loss

Total hemoglobin loos measured by difference between hemoglobin preoperatively and the fourth postoperative day (NCT01850394)
Timeframe: 5 days after surgery

Interventiong/dL (Mean)
Control Group2.9
TXA-250 Group2.2
TXA-500 Group2.2

Knee Function Scores

"Knee function score was measured with 2 methods, and were evaluated preoperatively and then postoperatively at 3-month, 6-month, and 1-year period.~Knee Society Knee Score using for rating knee function measurement and subdivided into two parts; knee score and function score 1.1. Knee score : calculated from pain, presence of deformity, total range of flexion, alignment, and stability. Total score is 100 (0-100), more score means better.~1.2. Function score : calculated from patient's ability to walk and climb stairs. The score ranges from 0-100, more score means better.~Western Ontario and McMaster Universities Arthritis Index or WOMAC score : a widely used, standardized questionnaires for evaluating the condition of patients with knee osteoarthritis, including pain (score = 0-20), stiffness (0-8), and functional limitation (0-68). Total score ranges from 0-68, lower score means better." (NCT01850394)
Timeframe: 1 year after surgery

,,
Interventionunits on a scale (Mean)
Knee Society Knee score at 1 yearWOMAC score at 1 year
Control Group148.915.5
TXA-250 Group151.215.1
TXA-500 Group150.914.5

Number of Patients Having Postoperative Complications

"Postoperative complications were measured as an incidence of the following complications;~wound hematoma~surgical site infection~systemic infection~deep vein thrombosis~pulmonary embolism~knee stiffness requiring manipulation~medical complication such as myocardial infarction, congestive hear failure" (NCT01850394)
Timeframe: postoperative 1-year period

,,
Interventionparticipants (Number)
Re-clamp incidenceRe-dressing incidenceVenous thromboembolic complicationCongestive heart failure
Control Group6340
TXA-250 Group1011
TXA-500 Group0020

Perioperative Blood Loss

"Drainage blood loss measured by accumulating total drainage volume postoperatively~Calculated total blood loss measured by using specific formula and difference between hematocrit preoperatively and the fourth postoperative day" (NCT01850394)
Timeframe: 5 days after surgery

,,
Interventionml (Median)
Drainage blood lossCalculated total blood loss
Control Group546.9329.2
TXA-250 Group475.0239.7
TXA-500 Group430.2217.2

Reviews

41 reviews available for tranexamic acid and Deep Vein Thrombosis

ArticleYear
Meta-Analysis of the Efficacy and Safety of Tranexamic Acid in Spinal Surgery.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Databases, Factual; Humans; Odds Ratio; PubMed; Tranexamic Acid; Venous Thrombosis

2022
A Systematic Review of Tranexamic Acid-Associated Venous Thromboembolic Events in Combat Casualties and Considerations for Prolonged Field Care.
    Military medicine, 2023, 08-29, Volume: 188, Issue:9-10

    Topics: Antifibrinolytic Agents; Hemorrhage; Humans; Tranexamic Acid; Venous Thromboembolism; Venous Thrombo

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Efficacy and safety of tranexamic acid in posterior lumbar interbody fusion: a meta-analysis of randomized controlled trials.
    Journal of orthopaedic surgery and research, 2023, Jan-05, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; System

2023
The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.
    Orthopaedic surgery, 2023, Volume: 15, Issue:4

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures.
    The Cochrane database of systematic reviews, 2023, 06-05, Volume: 6

    Topics: Arthroplasty, Replacement; Fibrinogen; Fractures, Bone; Hemorrhage; Hemostatics; Humans; Myocardial

2023
Efficacy and safety of single- and double-dose intravenous tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2023, Aug-10, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
The optimal regimen of oral tranexamic acid administration for primary total knee/hip replacement: a meta-analysis and narrative review of a randomized controlled trial.
    Journal of orthopaedic surgery and research, 2020, Oct-06, Volume: 15, Issue:1

    Topics: Administration, Oral; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Comparison of oral versus intravenous tranexamic acid in total knee and hip arthroplasty: A GRADE analysis and meta-analysis.
    Medicine, 2020, Oct-30, Volume: 99, Issue:44

    Topics: Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replace

2020
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.
    Transfusion medicine reviews, 2017, Volume: 31, Issue:3

    Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans;

2017
The efficacy and safety of tranexamic acid in revision total knee arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2017, Jun-21, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Length of St

2017
Most Effective Regimen of Tranexamic Acid for Reducing Bleeding and Transfusions in Primary Total Knee Arthroplasty: A Meta-Analysis of Randomized Controlled Trials.
    The journal of knee surgery, 2018, Volume: 31, Issue:7

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2018
The efficacy of combined intra-articular and intravenous tranexamic acid for blood loss in primary total knee arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:42

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:52

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Tranexamic acid plus drain-clamping can reduce blood loss in total knee arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2018, Volume: 52

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2018
Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2018, Volume: 54, Issue:Pt A

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials.
    BMC musculoskeletal disorders, 2018, Sep-07, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2018, Dec-03, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2018
Transfusions and cost-benefit of oral versus intravenous tranexamic acid in primary total hip arthroplasty: A meta-analysis of randomized controlled trials.
    Medicine, 2019, Volume: 98, Issue:17

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2019
Oral vs intravenous tranexamic acid in total-knee arthroplasty and total hip arthroplasty: A systematic review and meta-analysis.
    Medicine, 2019, Volume: 98, Issue:20

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Antifibrinolytic

2019
Use of intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2013, Volume: 16, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2013
Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014, Volume: 22, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Dose-Response Relati

2014
The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis.
    The Journal of surgical research, 2014, Volume: 186, Issue:1

    Topics: Anti-Arrhythmia Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Humans; Orthopedic Pr

2014
A systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement.
    The bone & joint journal, 2014, Volume: 96-B, Issue:8

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2014
Topical application of tranexamic acid in primary total hip arthroplasty: a systemic review and meta-analysis.
    International journal of surgery (London, England), 2015, Volume: 15

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion;

2015
Effect of Topical Tranexamic Acid in Reducing Bleeding and Transfusions in TKA.
    Orthopedics, 2015, Volume: 38, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
Safety and Efficacy of Tranexamic Acid in Total Knee Arthroplasty.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Oct-14, Volume: 21

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; D

2015
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Intravenous versus topical tranexamic acid in primary total hip replacement: A systemic review and meta-analysis.
    International journal of surgery (London, England), 2016, Volume: 32

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Topical fibrin sealant versus intravenous tranexamic acid for reducing blood loss following total knee arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2016, Volume: 32

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
The effectiveness and safety of tranexamic acid in bilateral total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:39

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusion; Female; Humans; M

2016
Combined use of intravenous and topical versus intravenous tranexamic acid in primary total joint arthroplasty: A meta-analysis of randomized controlled trials.
    International journal of surgery (London, England), 2017, Volume: 38

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:50

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2017, 02-21, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Arthroplasty, Replacement, Hip; Blood Loss, Su

2017
What influence do anticoagulants have on oral implant therapy? A systematic review.
    Clinical oral implants research, 2009, Volume: 20 Suppl 4

    Topics: Administration, Oral; Administration, Topical; Anticoagulants; Atrial Fibrillation; Contraindication

2009
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Deep vein thrombosis, tranexamic acid, and a negative d-dimer.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2012, Volume: 18, Issue:6

    Topics: Antifibrinolytic Agents; Antipsychotic Agents; Female; Fibrin Fibrinogen Degradation Products; Human

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysis.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2007, Volume: 7, Issue:1

    Topics: Adult; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Transfusion; Controlled Cl

2007

Trials

36 trials available for tranexamic acid and Deep Vein Thrombosis

ArticleYear
Effect of Sequential Intravenous and Oral Tranexamic Acid on Hemoglobin Drop After Total Knee Arthroplasty: A Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2022, 01-19, Volume: 104, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2022
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Apr-15, Volume: 36, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2022
Medullary cavity application of tranexamic acid to reduce blood loss in tibial intramedullary nailing procedures-a randomized controlled trial.
    International orthopaedics, 2023, Volume: 47, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Exsanguination; Fracture Fixation, Intramedullary; Hu

2023
Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study.
    The Knee, 2023, Volume: 44

    Topics: Administration, Intravenous; Adult; Anticoagulants; Antifibrinolytic Agents; Arthritis; Arthroplasty

2023
Comparison of oral vs. combined topical/intravenous/oral tranexamic acid in the prevention of blood loss in total knee arthroplasty: A randomised clinical trial.
    Orthopaedics & traumatology, surgery & research : OTSR, 2019, Volume: 105, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.
    The Journal of bone and joint surgery. American volume, 2019, Dec-04, Volume: 101, Issue:23

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Blin

2019
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2020, 06-20, Volume: 395, Issue:10241

    Topics: Acute Disease; Adult; Aged; Antifibrinolytic Agents; Case-Control Studies; Double-Blind Method; Fema

2020
Combined use of intravenous and topical tranexamic acid efficiently reduces blood loss in patients aged over 60 operated with a 2-level lumbar fusion.
    Journal of orthopaedic surgery and research, 2020, Aug-20, Volume: 15, Issue:1

    Topics: Administration, Topical; Age Factors; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2020
Tranexamic acid reduces blood cost in long-segment spinal fusion surgery: A randomized controlled study protocol.
    Medicine, 2020, 09-11, Volume: 99, Issue:37

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female; Human

2020
Early intravenous tranexamic acid intervention reduces post-traumatic hidden blood loss in elderly patients with intertrochanteric fracture: a randomized controlled trial.
    Journal of orthopaedic surgery and research, 2021, Feb-03, Volume: 16, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage

2021
Tranexamic Acid for the Prevention of Blood Loss after Cesarean Delivery.
    The New England journal of medicine, 2021, 04-29, Volume: 384, Issue:17

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Transfusion; Cesarean Section; Do

2021
Intra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:11

    Topics: Administration, Intravenous; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee;

2017
The effect of tranexamic acid on hidden bleeding in older intertrochanteric fracture patients treated with PFNA.
    Injury, 2018, Volume: 49, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation, Intramedullary; Hip

2018
Multiple-Dose Intravenous Tranexamic Acid Further Reduces Hidden Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:9

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2018
OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2019, Volume: 29, Issue:3

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Doubl

2019
Tranexamic acid in primary total knee arthroplasty without tourniquet: a randomized, controlled trial of oral versus intravenous versus topical administration.
    Scientific reports, 2018, 09-11, Volume: 8, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthritis, Rheumat

2018
Comparative Efficacy of Intravenous With Intra-articular Versus Intravenous Only Administration of Tranexamic Acid to Reduce Blood Loss in Knee Arthroplasty.
    Orthopedics, 2018, Nov-01, Volume: 41, Issue:6

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2018
Intravenous and Oral Tranexamic Acid Are Equivalent at Reducing Blood Loss in Thoracolumbar Spinal Fusion: A Prospective Randomized Trial.
    Spine, 2019, Jun-01, Volume: 44, Issue:11

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Blood Loss, Surgic

2019
Clinical value of tranexamic acid in unilateral and simultaneous bilateral TKAs under a contemporary blood-saving protocol: a randomized controlled trial.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014, Volume: 22, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusion; Clinical Protocol

2014
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trial.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

2015
[A PROSPECTIVE RANDOMIZED SELF-CONTROLLED STUDY ON EFFECT OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS IN TOTAL KNEE ARTHROPLASTY].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2015, Volume: 29, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2015
Combined Administration of Systemic and Topical Tranexamic Acid for Total Knee Arthroplasty: Can It Be a Better Regimen and Yet Safe? A Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses.
    Thrombosis research, 2016, Volume: 141

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood

2016
The Efficacy and Safety of Combination of Intravenous and Topical Tranexamic Acid in Revision Hip Arthroplasty: A Randomized, Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Animals; Antifibrinolytic Agents; Arthro

2016
Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomark

2016
Tranexamic Acid Administration in Primary Total Hip Arthroplasty: A Randomized Controlled Trial of Intravenous Combined with Topical Versus Single-Dose Intravenous Administration.
    The Journal of bone and joint surgery. American volume, 2016, Jun-15, Volume: 98, Issue:12

    Topics: Administration, Intravenous; Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Arthropl

2016
Peri-articular tranexamic acid injection in total knee arthroplasty: a randomized controlled trial.
    BMC musculoskeletal disorders, 2016, 07-26, Volume: 17

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood T

2016
Peri-articular tranexamic acid injection in total knee arthroplasty: a randomized controlled trial.
    BMC musculoskeletal disorders, 2016, 07-26, Volume: 17

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood T

2016
Peri-articular tranexamic acid injection in total knee arthroplasty: a randomized controlled trial.
    BMC musculoskeletal disorders, 2016, 07-26, Volume: 17

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood T

2016
Peri-articular tranexamic acid injection in total knee arthroplasty: a randomized controlled trial.
    BMC musculoskeletal disorders, 2016, 07-26, Volume: 17

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood T

2016
The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2017
Efficacy of a Single Dose and an Additional Dose of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
Effects of tranexamic acid on blood loss during total hip arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2010, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2010
Risk of deep venous thrombosis in drain clamping with tranexamic acid and carbazochrome sodium sulfonate hydrate in total knee arthroplasty.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:1

    Topics: Adrenochrome; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Constriction; Female;

2012
The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013, Volume: 21, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Atrial Fibrillation; Blood Loss, Sur

2013
The postoperative blood-sparing efficacy of oral versus intravenous tranexamic acid after total knee replacement.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2004
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006
Tranexamic acid reduces early post-operative blood loss after total knee arthroplasty: a prospective randomised controlled trial of 29 patients.
    The Knee, 2006, Volume: 13, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Double-Blind Method; Fema

2006

Other Studies

38 other studies available for tranexamic acid and Deep Vein Thrombosis

ArticleYear
No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA.
    Clinical orthopaedics and related research, 2022, 04-01, Volume: 480, Issue:4

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2022
[Effects of oral and intravenous tranexamic acid on perioperative blood loss after lumbar spinal canal decompression and fusion].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2022, Aug-25, Volume: 35, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Decompression; Humans; Postoperative Hemorrhage; Spin

2022
Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients.
    Medicina (Kaunas, Lithuania), 2022, Nov-29, Volume: 58, Issue:12

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Retrospective St

2022
Does tranexamic acid increase venous thromboembolism risk among trauma patients? A prospective multicenter analysis across 17 level I trauma centers.
    Injury, 2023, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Humans; Prospective Studies; Pulmonary Embolism; Tranexamic Acid; Trauma Centers;

2023
Postoperative ultrasound evaluation for deep vein thrombosis after knee replacement surgery performed with tranexamic acid.
    Minerva anestesiologica, 2020, Volume: 86, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans

2020
One Versus Two Doses of Intravenous Tranexamic Acid in Total Knee Arthroplasty.
    The journal of knee surgery, 2021, Volume: 34, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2021
Periarticular Injection of Tranexamic Acid Reduces Blood Loss and the Necessity for Allogeneic Transfusion After Total Knee Arthroplasty Using Autologous Transfusion: A Retrospective Observational Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2018
Does tranexamic acid increase the risk of thromboembolism after bilateral simultaneous total knee arthroplasties in Asian Population?
    Archives of orthopaedic and trauma surgery, 2018, Volume: 138, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Asian Peop

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Intravenous Tranexamic Acid Reduces Postoperative Blood Loss After High Tibial Osteotomy.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:11

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Humans; Infusions, Intravenous; Male; Mid

2018
Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism.
    The journal of trauma and acute care surgery, 2019, Volume: 86, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Female; Hemorrhage; Humans; Injury Severity Score

2019
Comparison of three routes of administration of tranexamic acid in primary unilateral total knee arthroplasty: Analysis of a national database.
    Thrombosis research, 2019, Volume: 173

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2019
Orthotopic liver transplantation in a patient receiving apixaban for portal vein thrombosis.
    Journal of clinical anesthesia, 2019, Volume: 56

    Topics: Aged; Blood Loss, Surgical; Carcinoma, Hepatocellular; Dabigatran; Humans; Infusions, Intravenous; L

2019
Intravenous tranexamic acid safely and effectively reduces transfusion rates in revision total hip arthroplasty.
    The bone & joint journal, 2019, Volume: 101-B, Issue:6_Supple_B

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2019
Intra-articular 1 g tranexamic acid administration during total knee arthroplasty is safe and effective for the reduction of blood loss and blood transfusion.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2019, Volume: 29, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusion; Blood Volume; Con

2019
Can tranexamic acid and hydrogen peroxide reduce blood loss in cemented total knee arthroplasty?
    Archives of orthopaedic and trauma surgery, 2014, Volume: 134, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2014
Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplast

2015
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
[Effectiveness of tranexamic acid in total knee arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2014, Volume: 28, Issue:11

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2014
Does tranexamic acid alter the risk of thromboembolism after total hip arthroplasty in the absence of routine chemical thromboprophylaxis?
    The bone & joint journal, 2015, Volume: 97-B, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Case-Control Studies; Female; Hip Joi

2015
Does Tranexamic Acid Reduce Blood Loss and Transfusion Requirements Associated With the Periacetabular Osteotomy?
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:8

    Topics: Acetabulum; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Dru

2015
Intra-articular administration of tranexamic acid in total hip arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2015, Volume: 23, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Female; Humans; In

2015
Balancing Thromboprophylaxis and Bleeding in Total Joint Arthroplasty: Impact of Eliminating Enoxaparin and Predonation and Implementing Pneumatic Compression and Tranexamic Acid.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:6

    Topics: Aged; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replace

2016
Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty; Aspirin; Blood Loss, Surgical; Cohort Studies; Female;

2016
A protocol for management of blood loss in surgical treatment of peritoneal malignancy by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
    Transfusion medicine (Oxford, England), 2016, Volume: 26, Issue:2

    Topics: Blood Component Transfusion; Blood Loss, Surgical; Cytoreduction Surgical Procedures; Factor VIII; F

2016
Tranexamic acid in total joint arthroplasty.
    ANZ journal of surgery, 2016, Volume: 86, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Post

2016
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:2

    Topics: Administration, Oral; Adult; Asian People; Dermatologic Agents; Facial Dermatoses; Female; Gastroint

2016
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:2

    Topics: Administration, Oral; Adult; Asian People; Dermatologic Agents; Facial Dermatoses; Female; Gastroint

2016
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:2

    Topics: Administration, Oral; Adult; Asian People; Dermatologic Agents; Facial Dermatoses; Female; Gastroint

2016
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:2

    Topics: Administration, Oral; Adult; Asian People; Dermatologic Agents; Facial Dermatoses; Female; Gastroint

2016
Intravenous versus topical tranexamic acid administration in primary total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017, Volume: 25, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Chemical Thromboprophylaxis Is Not Necessary to Reduce Risk of Thromboembolism With Tranexamic Acid After Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Trans

2017
Tranexamic acid use and risk of thrombosis in regular users ofantithrombotics undergoing primary total knee arthroplasty: a prospectivecohort study.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fibrinolytic Agents;

2018
A comparative, retrospective study of peri-articular and intra-articular injection of tranexamic acid for the management of postoperative blood loss after total knee arthroplasty.
    BMC musculoskeletal disorders, 2016, 10-19, Volume: 17, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusion; Drainage; Female;

2016
Prevalence of Venous Thromboembolic Events Is Low in Asians After Total Knee Arthroplasty Without Chemoprophylaxis.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:3

    Topics: Aged; Arthroplasty, Replacement, Knee; Asian People; Chemoprevention; Female; Humans; Male; Middle A

2017
Low Risk of Thromboembolic Events After Routine Administration of Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:4

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anesthesia; Antifibrinolytic Agents; Arthropla

2017
Tranexamic Acid Was Safe in Arthroplasty Patients With a History of Venous Thromboembolism: A Matched Outcome Study.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:9S

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthropl

2017
Hereditary haemorrhagic telangiectasia (HHT): negotiating between the Scylla of bleeding and Charybdis of thrombosis.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Cardiomyopathy, Hypertrophic; Colectomy; Colostomy; Embolization, Th

2008
Extensive venous thrombosis following administration of high-dose glucocorticosteroids and tranexamic acid in relapsed Evans syndrome.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2008, Volume: 19, Issue:7

    Topics: Anemia, Hemolytic, Autoimmune; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Mi

2008
Management of May-Hegglin anomaly referred for coronary artery bypass.
    Platelets, 2011, Volume: 22, Issue:6

    Topics: Adult; Anesthetics; Blood Platelets; Cell Size; Coronary Artery Bypass; Diabetes Complications; Diab

2011
Treatment of postoperative bleeding after fondaparinux with rFVIIa and tranexamic acid.
    The Netherlands journal of medicine, 2005, Volume: 63, Issue:5

    Topics: Aged; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Drug Therapy, Combina

2005
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001
No increased risk of venous thrombosis in women taking tranexamic acid.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Case-Control Studies; Female; Humans; Middle Aged; Retro

2001