Page last updated: 2024-11-05

tranexamic acid and Coxarthrosis

tranexamic acid has been researched along with Coxarthrosis in 17 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid (TXA) has demonstrated efficacy in reducing blood loss, reduction in hemoglobin, and blood transfusion requirements in primary total hip arthroplasty (THA)."2.87Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study. ( Luo, ZY; Pei, FX; Wang, D; Wang, HY; Zhou, K; Zhou, ZK, 2018)
"No patient in either group developed deep vein thrombosis or pulmonary embolism up to 3 months."2.75Effects of tranexamic acid on blood loss during total hip arthroplasty. ( Ballal, MS; Denn, PG; Mitchell, P; Singh, J, 2010)
"The volume of postoperative blood loss was recorded at two-hour intervals for the first twelve hours and then again at twenty-four hours, and the values were compared between the two groups."2.71Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty. ( Fuji, T; Masuhara, K; Yamasaki, S, 2005)
"Tranexamic acid appears to be an effective and economic drug for reduction of blood loss in cemented primary hip arthroplasty for osteoarthritis."2.71Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis. ( Korkala, OL; Niskanen, RO, 2005)
"Tranexamic acid (TA) is a potent drug to reduce surgical blood loss in surgery, therefore, as a potential drug for application in THA."2.55Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials. ( Hu, Y; Lei, P; Su, W; Zeng, M; Zhu, J; Zhu, Y, 2017)
"Thirty-four patients with haemophilia A undergoing 24 TKA and 18 THA were evaluated in this retrospective study (No."1.51Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia. ( Huang, Q; Huang, ZY; Ma, J; Pei, FX; Shen, B; Zeng, HJ; Zhou, ZK, 2019)
"Tranexamic acid was superior to fibrin sealant in decreasing allogeneic transfusion requirements (0 vs."1.46Tranexamic acid versus fibrin sealant in primary total hip replacement: a comparative study. ( Borbora, A; Kumar, G; Mahmood, A; Peter, V; Sawalha, S, 2017)
"Tranexamic acid (TA) is an inexpensive antifibrinolytic agent that is little used in orthopaedic surgery due to the absence of standardised optimal administration regimens."1.38Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery. ( Argenson, JN; Hémon, Y; Irisson, E; Kerbaul, F; Parratte, S; Pauly, V, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (29.41)29.6817
2010's12 (70.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, ZY1
Huang, Q1
Zeng, HJ1
Ma, J1
Shen, B2
Zhou, ZK2
Pei, FX3
Xu, X1
Jiang, J1
Liu, W1
Li, X1
Lu, H1
Piolanti, N1
Del Chiaro, A1
Matassi, F1
Graceffa, A1
Nistri, L1
Marcucci, M1
Lošťák, J1
Gallo, J1
Večeřa, M1
Špička, J1
Langová, K1
Luo, ZY1
Wang, HY1
Wang, D1
Zhou, K1
Zhu, J1
Zhu, Y1
Lei, P1
Zeng, M1
Su, W1
Hu, Y1
Grant, AL1
Letson, HL1
Morris, JL1
McEwen, P1
Hazratwala, K1
Wilkinson, M1
Dobson, GP1
Yamaguchi, A1
Goto, K1
Kawai, T1
Kuroda, Y1
Sano, K1
Matsuda, S1
Wu, YG1
Zeng, Y1
Si, HB1
Cao, F1
Yang, TM1
Mahmood, A1
Sawalha, S1
Borbora, A1
Kumar, G1
Peter, V1
Singh, J1
Ballal, MS1
Mitchell, P1
Denn, PG1
Irisson, E1
Hémon, Y1
Pauly, V1
Parratte, S1
Argenson, JN1
Kerbaul, F1
Garneti, N1
Field, J1
Yamasaki, S1
Masuhara, K1
Fuji, T1
Hynes, MC1
Calder, P1
Rosenfeld, P1
Scott, G1
Niskanen, RO1
Korkala, OL1
Benoni, G1
Fredin, H1
Knebel, R1
Nilsson, P1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss, Transfusion Index and Complications After Total Hip Replacement. A Prospective, Randomized, Double Blind Clinical Trial[NCT04187014]Phase 290 participants (Actual)Interventional2020-02-06Completed
Extended Postoperative Tranexamic Acid Use in Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial[NCT05099276]Phase 446 participants (Actual)Interventional2021-12-07Active, not recruiting
Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events[NCT05313620]Phase 430 participants (Anticipated)Interventional2022-04-01Recruiting
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
Randomized Placebo Controlled Study Using Tranexamic Acid in Revision Total Hip Arthroplasty[NCT00375440]0 participants (Actual)Interventional2005-02-28Withdrawn (stopped due to Study halted prematurely as investigator left the institution.)
Intravenous Tranexamic Acid to Reduce Blood Loss in Reverse Total Shoulder Arthroplasty[NCT02043132]Phase 2/Phase 3116 participants (Actual)Interventional2013-09-30Completed
The Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin / Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: a Prospective, Randomized, Double-blinded, Multicenter Study[NCT05357079]Early Phase 198 participants (Anticipated)Interventional2017-08-25Recruiting
Topical Application of Tranexamic Acid to Reduce Postoperative Blood Loss in Posterior Approach Spinal Surgery[NCT02063035]Phase 429 participants (Actual)Interventional2012-08-31Completed
Range of Motion and Function Following Primary Repair of Traumatic Zone 1 or Zone 2 Digit Flexor Tendon Injuries - Impact of Tranexamic Acid Use - A Prospective Study[NCT04178655]Early Phase 148 participants (Anticipated)Interventional2019-11-30Not yet recruiting
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty[NCT03825939]Phase 452 participants (Actual)Interventional2015-04-21Terminated (stopped due to Lack of patient enrollment due to only one surgeon that was enrolling.)
Role of Topical Tranexamic Acid in Total Hip Arthroplasty[NCT01866943]Phase 241 participants (Actual)Interventional2011-11-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Number of Participants Experiencing Deep Vein Thrombosis

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Deep venous thrombosis" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Hematoma as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Hematoma" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Infection as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Infection" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Myocardial Infarction

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Myocardial infarction" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline1

Number of Participants Experiencing Pulmonary Embolism

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Pulmonary Embolism" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Total Blood Loss

Total Blood Loss as calculated according to method as described by Good et al. Total Blood Loss (mL) = 1000 X Hb(loss)/Hb(initial) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

InterventionTotal Blood Loss (mL) (Mean)
Tranexamic Acid1122.4
Normal Saline1472

Total Drain Output

Total Drain Output as measured postoperatively 0-48 hours (NCT02043132)
Timeframe: 0-48 hours postoperatively

InterventionmL (Mean)
Tranexamic Acid221
Normal Saline372

Total Hemoglobin Loss

Total hemoglobin loss estimated using the formula for total blood volume described by Nadler et al Hb(loss) = blood volume (L) x [Hb(initial)(g/L) - Hb(final)(g/L)] + Hb(transfused) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

Interventiong (Mean)
Tranexamic Acid154.6
Normal Saline200.1

Blood Loss Volume Following Surgery

Blood loss following surgery was defined as the total amount of fluid collected from the drain in the wound site during the hospital stay. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 5 days

InterventionmL (Median)
Tranexamic Acid534
Placebo530

Change in Hemoglobin Level From Preoperative Appointment to Postoperative Hospital Discharge

Blood loss was calculated from the difference between the level of hemoglobin at the preoperative appointment and the lowest level during the postoperative hospitalization period. Reported here is the change in hemoglobin level after surgery. A negative number indicates a reduction in hemoglobin level. (NCT02063035)
Timeframe: From preoperative appointment approximately one week before surgery to end of hospital stay up to approximately 5 days after surgery

Interventiongrams per deciliter (g/dL) (Median)
Tranexamic Acid-3.2
Placebo-4.6

Hospital Length of Stay in Days

The number of days the participants stayed in the hospital after surgery was recorded. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 2 weeks

Interventiondays (Median)
Tranexamic Acid5
Placebo6

Post-operative Blood Transfusions During Hospitalization

All units of blood transfused during the hospital stay after surgery were recorded. One red blood cell unit contains 300 to 360 mL of whole blood. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 5 days

Interventionunits of blood (Median)
Tranexamic Acid0
Placebo0

Length of Hospital Stay

Measured in Days (NCT03825939)
Timeframe: At Hospital Discharge

InterventionDays (Mean)
Intravenous Tranexamic Acid3
Intravenous Placebo3
Intravenous Tranexamic Acid Followed by Intravenous Placebo3

Estimated Blood Loss

Estimated Blood Loss defined as Pre Op Hgb mins the Post Op Day two Hgb. (NCT01866943)
Timeframe: Pre Op, Post Op Day 2

InterventionHemoglobin (grams/deciliter) (Mean)
Baseline Population2.93

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 2 week

Interventionunits on a scale (Mean)
All Study Participants65.76

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 6 week

Interventionunits on a scale (Mean)
All Study Participants81.77

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: Preoperative

Interventionunits on a scale (Mean)
All Study Participants58.34

Mid Thigh Circumference

Measurement of the thigh at the half way point between the prominence of the greater trochanter and the lateral epicondyle of the femur. No data recorded at 2 weeks or 6 weeks for this study population. (NCT01866943)
Timeframe: Pre Op

Interventioncentimeters (Mean)
Baseline Population52.99

Reviews

1 review available for tranexamic acid and Coxarthrosis

ArticleYear
Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:52

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017

Trials

10 trials available for tranexamic acid and Coxarthrosis

ArticleYear
Application of thromboelastography to evaluate the effect of different routes administration of tranexamic acid on coagulation function in total hip arthroplasty.
    Journal of orthopaedic surgery and research, 2019, Dec-11, Volume: 14, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2019
Clinical and instrumental evaluation of two different regimens of tranexamic acid in total hip arthroplasty: a single-centre, prospective, randomized study with 80 patients.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Volume; F

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Combination of erythropoietin and tranexamic acid in bilateral simultaneous total hip arthroplasty: a randomised, controlled trial.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2016, Jul-25, Volume: 26, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Cell Count; Blood Transf

2016
Effects of tranexamic acid on blood loss during total hip arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2010, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2010
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty.
    The Journal of bone and joint surgery. American volume, 2005, Volume: 87, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemostatic Tech

2005
The use of tranexamic acid to reduce blood loss during total hip arthroplasty: an observational study.
    Annals of the Royal College of Surgeons of England, 2005, Volume: 87, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Cohort Studies; Femal

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001
Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations.
    Acta orthopaedica Scandinavica, 2001, Volume: 72, Issue:5

    Topics: Aged; Blood Preservation; Double-Blind Method; Female; Femur Head Necrosis; Hemoglobins; Humans; Mal

2001

Other Studies

6 other studies available for tranexamic acid and Coxarthrosis

ArticleYear
Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia.
    BMC musculoskeletal disorders, 2019, Sep-04, Volume: 20, Issue:1

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthralgia; Arthroplasty, Replacement,

2019
[Local Application of Tranexamic Acid in Total Hip Arthroplasty Decreases Blood Loss and Consumption of Blood Transfusion].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2017, Volume: 84, Issue:4

    Topics: Administration, Cutaneous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss

2017
Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study.
    Journal of orthopaedic surgery and research, 2018, Jun-18, Volume: 13, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Coagulation; Blood

2018
Dose optimization of topical tranexamic acid for primary total hip arthroplasty: A prospective cohort study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2019, Volume: 24, Issue:2

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Cohort Studi

2019
Tranexamic acid versus fibrin sealant in primary total hip replacement: a comparative study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017, Volume: 27, Issue:7

    Topics: Aerosols; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood

2017
Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery.
    Orthopaedics & traumatology, surgery & research : OTSR, 2012, Volume: 98, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplast

2012