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tranexamic acid and Chronic Kidney Failure

tranexamic acid has been researched along with Chronic Kidney Failure in 9 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Ligneous conjunctivitis is a rare severe conjunctivitis characterised by fibrin-rich, 'woody', pseudomembranes on the tarsal conjunctiva complicated by congenital hypoplasminogenaemia."5.40Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia. ( Izumi, N; Potts, LB; Song, Y; Yoshida, A, 2014)
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)."5.30Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998)
" In 16 episodes of bleeding TXA was used (in a dosage of 20 mg intravenously, followed for the next 4 weeks by 10 mg/kg/48 h orally), whereas in 20 other cases of bleeding, TXA was not used."2.71Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients. ( Lavre, J; Sabovic, M; Vujkovac, B, 2003)
" TXA in the dosage used was biologically active, since a significant decrease in plasminogen and D-dimer were found in both groups."2.71The effect of long-term, low-dose tranexamic acid treatment on platelet dysfunction and haemoglobin levels in haemodialysis patients. ( Cernelc, P; Lavre, J; Sabovic, M; Salobir, B; Vujkovac, B; Zupan, I; Zupan, IP, 2005)
"Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent commonly used for the prevention and treatment of bleeding disorders."2.55Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: A report of four cases and review of literature. ( Chow, KM; Kwan, BC; Leung, CB; Li, PK; Ma, TK; Szeto, CC, 2017)
"Ligneous conjunctivitis is a rare severe conjunctivitis characterised by fibrin-rich, 'woody', pseudomembranes on the tarsal conjunctiva complicated by congenital hypoplasminogenaemia."1.40Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia. ( Izumi, N; Potts, LB; Song, Y; Yoshida, A, 2014)
"Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD)."1.30Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient. ( Lavre, J; Sabovic, M; Vujkovac, B, 1998)
"Tranexamic acid is a potent antifibrinolytic drug frequently used in the treatment of haematuria and a number of other haemorrhagic conditions."1.26Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases. ( Andersson, L; Eriksson, O; Hedlund, PO; Kjellman, H; Lindqvist, B, 1978)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Song, Y1
Izumi, N1
Potts, LB1
Yoshida, A1
Revollo, JY1
Cuffy, MC1
Witte, DP1
Paterno, F1
Alloway, RR1
Woodle, ES1
Ma, TK1
Chow, KM1
Kwan, BC1
Leung, CB1
Szeto, CC1
Li, PK1
Kimura, SI1
Odawara, J1
Aoki, T1
Yamakura, M1
Takeuchi, M1
Watanabe, Y1
Matsue, K1
Sabovic, M3
Lavre, J3
Vujkovac, B3
Zupan, IP1
Salobir, B1
Zupan, I1
Cernelc, P1
Mezzano, D1
Panes, O1
Muñoz, B1
Pais, E1
Tagle, R1
González, F1
Mezzano, S1
Barriga, F1
Pereira, J1
Andersson, L1
Eriksson, O1
Hedlund, PO1
Kjellman, H1
Lindqvist, B1

Reviews

1 review available for tranexamic acid and Chronic Kidney Failure

ArticleYear
Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: A report of four cases and review of literature.
    Nephrology (Carlton, Vic.), 2017, Volume: 22, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Blood Loss, Surgic

2017

Trials

3 trials available for tranexamic acid and Chronic Kidney Failure

ArticleYear
Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Combined Modality Therapy; Female; Gastrointestinal Hemorrhage; Hemos

2003
The effect of long-term, low-dose tranexamic acid treatment on platelet dysfunction and haemoglobin levels in haemodialysis patients.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Platelets; Erythropoietin; Female; Fibrin Fibrinogen Degradatio

2005
Tranexamic acid inhibits fibrinolysis, shortens the bleeding time and improves platelet function in patients with chronic renal failure.
    Thrombosis and haemostasis, 1999, Volume: 82, Issue:4

    Topics: Antifibrinolytic Agents; Bleeding Time; Fibrinolysis; Hemostasis; Humans; Kidney Failure, Chronic; P

1999

Other Studies

5 other studies available for tranexamic acid and Chronic Kidney Failure

ArticleYear
Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia.
    BMJ case reports, 2014, May-19, Volume: 2014

    Topics: Administration, Oral; Aged; Conjunctivitis; Dose-Response Relationship, Drug; Drug Administration Sc

2014
Case Report: Hemolytic Anemia Following Deceased Donor Renal Transplantation Associated With Tranexamic Acid Administration for Disseminated Intravascular Coagulation.
    Transplantation proceedings, 2015, Volume: 47, Issue:7

    Topics: Aged; Anemia, Hemolytic; Antifibrinolytic Agents; Diabetes Mellitus, Type 2; Disseminated Intravascu

2015
Use of tranexamic acid for disseminated intravascular coagulation with excessive fibrinolysis associated with aortic dissection in a patient with chronic renal failure.
    International journal of hematology, 2009, Volume: 89, Issue:4

    Topics: Aged; Aortic Aneurysm; Disseminated Intravascular Coagulation; Fibrinolysis; Humans; Kidney Failure,

2009
Successful treatment of bleeding from colonic angiodysplasias with tranexamic acid in a hemodialysis patient.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 31, Issue:3

    Topics: Angiodysplasia; Antifibrinolytic Agents; Colonic Diseases; Gastrointestinal Hemorrhage; Humans; Kidn

1998
Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases.
    Urological research, 1978, Volume: 6, Issue:2

    Topics: Biological Availability; Chronic Disease; Creatinine; Cyclohexanecarboxylic Acids; Glomerulonephriti

1978