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tranexamic acid and Chronic Disease

tranexamic acid has been researched along with Chronic Disease in 21 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"A double-blind study with tranexamic acid (Cyklokapron) was carried out in 17 patients with chronic urticaria."9.04Tranexamic acid (Cyklokapron) in chronic urticaria: a double-blind study. ( Laurberg, G, 1977)
"Tranexamic acid (TA) used in a variety of conditions associated with bleeding has been associated with potential thrombotic side effects such as formation of thrombi and pulmonary embolism (PE)."7.77Recurrent pulmonary embolism associated with a hemostatic drug: tranexamic acid. ( Krivokuca, I; Lammers, JW, 2011)
"The management of chronic disseminated intravascular coagulation (DIC) caused by aortic dissection has not yet been established."5.46Tranexamic Acid Controlled Chronic Disseminated Intravascular Coagulation Associated with Aortic Dissection and Patent False Lumen for Three Years. ( Adachi, T; Gatate, Y; Kawamura, A; Masaki, N; Namba, T; Sato, A; Yada, H; Yasuda, R, 2017)
"An 82-year-old female with a history of aortic dissection was admitted to our hospital for evaluation of thrombocytopenia and a bleeding tendency."5.39[Effective treatment with tranexamic acid for chronic disseminated intravascular coagulation associated with aortic dissection]. ( Hirano, T; Morikawa, K; Tsuda, H; Tsuji, T; Yamasaki, H, 2013)
"A double-blind study with tranexamic acid (Cyklokapron) was carried out in 17 patients with chronic urticaria."5.04Tranexamic acid (Cyklokapron) in chronic urticaria: a double-blind study. ( Laurberg, G, 1977)
" It is not possible to determine whether human activated protein C, recombinant human soluble thrombomodulin, tranexamic acid and dermatan sulphate are effective or harmful for patients presenting with DIC related to acute or chronic leukemia."4.91Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia. ( Anand, V; Martí-Carvajal, AJ; Solà, I, 2015)
" It is not possible to determine whether human activated protein C, recombinant human soluble thrombomodulin, tranexamic acid and dermatan sulphate are effective or harmful for patients presenting with DIC related to acute or chronic leukemia."4.87Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia. ( Cardona, AF; Martí-Carvajal, AJ; Simancas, D, 2011)
"Tranexamic acid (TA) used in a variety of conditions associated with bleeding has been associated with potential thrombotic side effects such as formation of thrombi and pulmonary embolism (PE)."3.77Recurrent pulmonary embolism associated with a hemostatic drug: tranexamic acid. ( Krivokuca, I; Lammers, JW, 2011)
" We present a case of postmenopausal bleeding, because of chronic DIC, which resulted from aortic aneurysm and was managed with replacement blood products and tranexamic acid."3.72Postmenopausal bleeding due to chronic DIC. ( Bollapragada, SS; Garg, M; McFarlane, T, 2004)
"Tranexamic acid is an antifibrinolytic that is known to reduce operative bleeding."2.78Intravenous tranexamic acid and intraoperative visualization during functional endoscopic sinus surgery: a double-blind randomized controlled trial. ( Chiarella, A; Côté, DW; Dziegielewski, PT; Langille, MA; Mulholland, G; Sowerby, LJ; Wright, ED, 2013)
"Gingival hemorrhage is recognized as a symptom of MDS, a rare group of potentially fatal hematological disorders, but it has not previously been documented as a presenting sign."2.40Gingival hemorrhage, myelodysplastic syndromes, and acute myeloid leukemia. A case report. ( Chapple, IL; Murray, JA; Saxby, MS, 1999)
"The management of chronic disseminated intravascular coagulation (DIC) caused by aortic dissection has not yet been established."1.46Tranexamic Acid Controlled Chronic Disseminated Intravascular Coagulation Associated with Aortic Dissection and Patent False Lumen for Three Years. ( Adachi, T; Gatate, Y; Kawamura, A; Masaki, N; Namba, T; Sato, A; Yada, H; Yasuda, R, 2017)
"Subacute invasive pulmonary aspergillosis (formerly called chronic necrotising pulmonary aspergillosis) is a more rapidly progressive infection (<3 months) usually found in moderately immunocompromised patients, which should be managed as invasive aspergillosis."1.43Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management. ( Ader, F; Beigelman-Aubry, C; Blot, S; Cadranel, J; Chakrabarti, A; Denning, DW; Dimopoulos, G; Lange, C; Ullmann, AJ, 2016)
"An 82-year-old female with a history of aortic dissection was admitted to our hospital for evaluation of thrombocytopenia and a bleeding tendency."1.39[Effective treatment with tranexamic acid for chronic disseminated intravascular coagulation associated with aortic dissection]. ( Hirano, T; Morikawa, K; Tsuda, H; Tsuji, T; Yamasaki, H, 2013)
"Though her hemoptysis improved, respiratory failure suddenly worsened."1.33[A case of acute exacerbation of chronic pulmonary thromboembolism with essential thrombocythemia during treatment for hemoptysis]. ( Abe, T; Haraguchi, M; Hayashi, M; Ito, K; Nakajima, H; Sakagami, T; Tsutsui, N, 2006)
"Tranexamic acid is a potent antifibrinolytic drug frequently used in the treatment of haematuria and a number of other haemorrhagic conditions."1.26Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases. ( Andersson, L; Eriksson, O; Hedlund, PO; Kjellman, H; Lindqvist, B, 1978)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's1 (4.76)18.2507
2000's3 (14.29)29.6817
2010's13 (61.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gatate, Y1
Masaki, N1
Sato, A1
Yasuda, R1
Namba, T1
Yada, H1
Kawamura, A1
Adachi, T1
Magen, E1
Chikovani, T1
Tsuji, T1
Morikawa, K1
Hirano, T1
Yamasaki, H1
Tsuda, H1
Jahanshahi, J1
Hashemian, F1
Pazira, S1
Bakhshaei, MH1
Farahani, F1
Abasi, R1
Poorolajal, J1
Izvin, AI1
Kuznetsova, NE1
Siniakov, AIu1
Martí-Carvajal, AJ2
Anand, V1
Solà, I1
Denning, DW1
Cadranel, J1
Beigelman-Aubry, C1
Ader, F1
Chakrabarti, A1
Blot, S1
Ullmann, AJ1
Dimopoulos, G1
Lange, C1
Desborough, M1
Hadjinicolaou, AV1
Chaimani, A1
Trivella, M1
Vyas, P1
Doree, C1
Hopewell, S1
Stanworth, SJ1
Estcourt, LJ1
Krivokuca, I1
Lammers, JW1
Van Sickels, NJ1
Hunsaker, RB1
Van Sickels, JE1
Asero, R1
Tedeschi, A1
Cugno, M1
Simancas, D1
Cardona, AF1
Langille, MA1
Chiarella, A1
Côté, DW1
Mulholland, G1
Sowerby, LJ1
Dziegielewski, PT1
Wright, ED1
Bollapragada, SS1
Garg, M1
McFarlane, T1
Amarapurkar, DN1
Patel, ND1
Abe, T1
Hayashi, M1
Sakagami, T1
Tsutsui, N1
Ito, K1
Nakajima, H1
Haraguchi, M1
Chapple, IL1
Saxby, MS1
Murray, JA1
Laurberg, G1
Tant, D1
Andersson, L1
Eriksson, O1
Hedlund, PO1
Kjellman, H1
Lindqvist, B1
Tomeoku, M1
Nakase, T1
Morita, K1
Katou, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339]Phase 20 participants (Actual)Interventional2022-03-31Withdrawn (stopped due to Challenges in recruitment)
Aspergillus-specific IgG Assays for the Diagnosis of Chronic Pulmonary Aspergillosis (CPA) in Chinese Patients -Multicenter Study[NCT03027089]560 participants (Anticipated)Observational2017-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for tranexamic acid and Chronic Disease

ArticleYear
Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia.
    The Cochrane database of systematic reviews, 2015, Jun-24, Issue:6

    Topics: Acute Disease; Anticoagulants; Chronic Disease; Dermatan Sulfate; Disseminated Intravascular Coagula

2015
Alternative agents to prophylactic platelet transfusion for preventing bleeding in people with thrombocytopenia due to chronic bone marrow failure: a meta-analysis and systematic review.
    The Cochrane database of systematic reviews, 2016, Oct-31, Volume: 10

    Topics: Benzoates; Bone Marrow Diseases; Chronic Disease; Deamino Arginine Vasopressin; Hemorrhage; Hemostat

2016
Hereditary angioedema: treatment, management, and precautions in patients presenting for dental care.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:2

    Topics: Acute Disease; Adult; Airway Obstruction; Aminocaproic Acid; Androgens; Angioedemas, Hereditary; Ant

2010
Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia.
    The Cochrane database of systematic reviews, 2011, Jun-15, Issue:6

    Topics: Acute Disease; Anticoagulants; Chronic Disease; Dermatan Sulfate; Disseminated Intravascular Coagula

2011
Gingival hemorrhage, myelodysplastic syndromes, and acute myeloid leukemia. A case report.
    Journal of periodontology, 1999, Volume: 70, Issue:10

    Topics: Acute Disease; Biopsy, Needle; Bone Marrow Cells; Chronic Disease; Diagnosis, Differential; Gingival

1999

Trials

3 trials available for tranexamic acid and Chronic Disease

ArticleYear
Effect of topical tranexamic acid on bleeding and quality of surgical field during functional endoscopic sinus surgery in patients with chronic rhinosinusitis: a triple blind randomized clinical trial.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Chronic D

2014
Intravenous tranexamic acid and intraoperative visualization during functional endoscopic sinus surgery: a double-blind randomized controlled trial.
    International forum of allergy & rhinology, 2013, Volume: 3, Issue:4

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Chemotherapy,

2013
Tranexamic acid (Cyklokapron) in chronic urticaria: a double-blind study.
    Acta dermato-venereologica, 1977, Volume: 57, Issue:4

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method;

1977

Other Studies

13 other studies available for tranexamic acid and Chronic Disease

ArticleYear
Tranexamic Acid Controlled Chronic Disseminated Intravascular Coagulation Associated with Aortic Dissection and Patent False Lumen for Three Years.
    Internal medicine (Tokyo, Japan), 2017, Volume: 56, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Aortic Aneurysm; Aortic Dissection; Chronic Disease; Disseminated Int

2017
Development of angio-oedema after omalizumab injections in a patient with chronic spontaneous urticaria.
    Clinical and experimental dermatology, 2018, Volume: 43, Issue:7

    Topics: Adult; Angioedema; Anti-Allergic Agents; Antifibrinolytic Agents; Chronic Disease; Female; Humans; I

2018
[Effective treatment with tranexamic acid for chronic disseminated intravascular coagulation associated with aortic dissection].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2013, Volume: 54, Issue:8

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Aortic Dissection; Chronic Disease; Disseminated Intrava

2013
[A rare case of thalassemia concomitant with chronic decompensated tonsillitis].
    Vestnik otorinolaringologii, 2014, Issue:3

    Topics: Adolescent; Anemia, Hypochromic; Antifibrinolytic Agents; Chemoprevention; Chronic Disease; Female;

2014
Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management.
    The European respiratory journal, 2016, Volume: 47, Issue:1

    Topics: Antifibrinolytic Agents; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Bronchial Arte

2016
Recurrent pulmonary embolism associated with a hemostatic drug: tranexamic acid.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Chronic Disease; Female; Hemoptysis; Humans; Middle Aged; Pulmonary Embolis

2011
Heparin and tranexamic Acid therapy may be effective in treatment-resistant chronic urticaria with elevated d-dimer: a pilot study.
    International archives of allergy and immunology, 2010, Volume: 152, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Cetirizine; Chr

2010
Postmenopausal bleeding due to chronic DIC.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Jan-15, Volume: 112, Issue:1

    Topics: Aged; Aortic Aneurysm; Blood Transfusion; Chronic Disease; Disseminated Intravascular Coagulation; F

2004
Gastric antral vascular ectasia (GAVE) syndrome.
    The Journal of the Association of Physicians of India, 2004, Volume: 52

    Topics: Aged; Anemia, Iron-Deficiency; Chronic Disease; Disease Progression; Female; Gastric Antral Vascular

2004
[A case of acute exacerbation of chronic pulmonary thromboembolism with essential thrombocythemia during treatment for hemoptysis].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:9

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Chronic Disease; Female; Hemoptysis; Humans; Ox

2006
Tranexamic acid in chronic urticaria.
    British medical journal, 1979, Jan-27, Volume: 1, Issue:6158

    Topics: Chronic Disease; Cyclohexanecarboxylic Acids; Humans; Tranexamic Acid; Urticaria

1979
Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases.
    Urological research, 1978, Volume: 6, Issue:2

    Topics: Biological Availability; Chronic Disease; Creatinine; Cyclohexanecarboxylic Acids; Glomerulonephriti

1978
[Chronic disseminated intravascular coagulation due to abdominal true aneurysm in two cases--effect of anti-platelet and anti-fibrinolytic therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:12

    Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Chronic Disease; Cyclohexanecarboxylic Acids; Disseminated

1989