Page last updated: 2024-11-05

tranexamic acid and Cerebral Ischemia

tranexamic acid has been researched along with Cerebral Ischemia in 12 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"A randomized controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, Cyklokapron; AB Kabi, Stockholm, Sweden) in the prevention of early rebleeding after the rupture of an intracranial aneurysm."9.05Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial. ( Fodstad, H; Forssell, A; Liliequist, B; Schannong, M, 1981)
"One hundred patients with a verified subarachnoid haemorrhage were studied in a double blind, placebo-controlled trial at a single centre to determine the value and relative risks of tranexamic acid (TXA) in the management of ruptured intracranial aneurysms."5.06Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study. ( Hitchcock, ER; Meyer, CH; Tsementzis, SA, 1990)
"A randomized controlled clinical trial was carried out to study the effect of tranexamic acid (AMCA, Cyklokapron; AB Kabi, Stockholm, Sweden) in the prevention of early rebleeding after the rupture of an intracranial aneurysm."5.05Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial. ( Fodstad, H; Forssell, A; Liliequist, B; Schannong, M, 1981)
"The occurrence of cerebral ischemia and other complications were recorded, and the effects of treatment were related to the clinical condition on admission."2.69Antifibrinolytic treatment in subarachnoid hemorrhage: a randomized placebo-controlled trial. STAR Study Group. ( Roos, Y, 2000)
"Tranexamic acid is an effective treatment to reduce blood loss."1.91The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan. ( Chen, JW; Hou, SM; Hsu, HW; Hsu, LI; Wei, ST, 2023)
"Cerebral ischemia was treated with vigorous plasma volume expansion under intermittent monitoring of pulmonary wedge pressure, cardiac output, and arterial blood pressure, aiming for a hematocrit of 0."1.30Impact of medical treatment on the outcome of patients after aneurysmal subarachnoid hemorrhage. ( Avezaat, CJ; Bijvoet, HW; Hasan, D; Vermeij, FH, 1998)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Hailu, K1
Ragoonanan, D1
Davis, H1
Hsu, LI3
Hsu, HW3
Chen, JW3
Wei, ST3
Hou, SM3
Mahmood, A1
Roberts, I1
Shakur, H1
Baharoglu, MI1
Germans, MR1
Rinkel, GJ1
Algra, A1
Vermeulen, M2
van Gijn, J1
Roos, YB1
Roos, Y2
Fodstad, H2
Forssell, A1
Liliequist, B1
Schannong, M1
Vermeij, FH1
Hasan, D1
Bijvoet, HW1
Avezaat, CJ1
Meijer, K1
Smid, WM1
Geerards, S1
van der Meer, J1
Stroobandt, G1
Lambert, O1
Menard, E1
Tsementzis, SA1
Hitchcock, ER1
Meyer, CH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid for the Treatment of Significant Traumatic Brain Injury: an International Randomised, Double Blind Placebo Controlled Trial[NCT01402882]Phase 312,737 participants (Actual)Interventional2012-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for tranexamic acid and Cerebral Ischemia

ArticleYear
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage.
    The Cochrane database of systematic reviews, 2013, Aug-30, Issue:8

    Topics: Administration, Oral; Aminocaproic Acid; Antifibrinolytic Agents; Brain Ischemia; Confidence Interva

2013
The association of tranexamic acid and nimodipine in the pre-operative treatment of ruptured intracranial aneurysms.
    Acta neurochirurgica, 1998, Volume: 140, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Antihypertensive Agents

1998

Trials

5 trials available for tranexamic acid and Cerebral Ischemia

ArticleYear
A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding M
    Trials, 2017, 07-17, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Brain Injuries, Traumatic; Brain Ischemia; Clinical Protocols; Double-Blind

2017
Tranexamic acid (AMCA) in aneurysmal subarachnoid haemorrhage.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1980, Volume: 14

    Topics: Adult; Aged; Brain Ischemia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Fibrin F

1980
Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial.
    Neurosurgery, 1981, Volume: 8, Issue:2

    Topics: Adult; Aged; Brain Ischemia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Humans;

1981
Antifibrinolytic treatment in subarachnoid hemorrhage: a randomized placebo-controlled trial. STAR Study Group.
    Neurology, 2000, Jan-11, Volume: 54, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Brain Ischemia; Calcium Channel Blockers; Drug Therapy, Combin

2000
Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study.
    Acta neurochirurgica, 1990, Volume: 102, Issue:1-2

    Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials as Topic; Cyclohexanecarbo

1990

Other Studies

5 other studies available for tranexamic acid and Cerebral Ischemia

ArticleYear
Tranexamic acid for treatment of symptomatic hemorrhagic conversion following administration of tenecteplase for acute ischemic stroke.
    The American journal of emergency medicine, 2022, Volume: 59

    Topics: Brain Ischemia; Fibrinolytic Agents; Humans; Ischemic Stroke; Stroke; Tenecteplase; Tissue Plasminog

2022
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Brain Ischemia; Glasgow Outcome Scale; Humans; Intracra

2003
Impact of medical treatment on the outcome of patients after aneurysmal subarachnoid hemorrhage.
    Stroke, 1998, Volume: 29, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Brain Ischemia; Female; Hemorrhage; Humans; Hydrocephalus; Int

1998
Hyperfibrinogenolysis in disseminated adenocarcinoma.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Adult; Afibrinogenemia; alpha-2-Antiplasmin; Antifibrinolytic Agents; Brain Ischemia

1998