Page last updated: 2024-11-05

tranexamic acid and Cerebral Infarction

tranexamic acid has been researched along with Cerebral Infarction in 5 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).

Research Excerpts

ExcerptRelevanceReference
"We enrolled 479 patients with subarachnoid hemorrhage in a multicenter, randomized, double-blind, placebo-controlled trial to determine whether treatment with the antifibrinolytic agent tranexamic acid improves outcome by preventing rebleeding."5.05Antifibrinolytic treatment in subarachnoid hemorrhage. ( Cheah, F; Hijdra, A; Lindsay, KW; Muizelaar, JP; Murray, GD; Schannong, M; Teasdale, GM; van Crevel, H; van Gijn, J; Vermeulen, M, 1984)
"Tranexamic acid has been shown to reduce perioperative blood loss without increasing the risk of venous thromboembolism after total knee replacement."1.39Cerebrovascular infarction following bilateral total knee arthroplasty and tranexamic acid administration. ( Baker, J; Bruce-Brand, R; Dragomir, R; Harty, J, 2013)
"We studied 471 consecutive patients with aneurysmal subarachnoid hemorrhage and used logistic regression with step-wise forward selection of variables."1.29Amount of blood on computed tomography as an independent predictor after aneurysm rupture. ( Brouwers, PJ; Dippel, DW; Hasan, D; Lindsay, KW; van Gijn, J; Vermeulen, M, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Post, R1
Germans, MR1
Coert, BA1
Rinkel, GJE1
Vandertop, WP1
Verbaan, D1
Bruce-Brand, R1
Dragomir, R1
Baker, J1
Harty, J1
Vermeulen, M3
Lindsay, KW3
Murray, GD2
Cheah, F1
Hijdra, A2
Muizelaar, JP2
Schannong, M1
Teasdale, GM2
van Crevel, H2
van Gijn, J3
Brouwers, PJ1
Dippel, DW1
Hasan, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage. A Prospective, Randomized, Multicenter Study.[NCT02684812]Phase 2/Phase 3955 participants (Actual)Interventional2012-07-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for tranexamic acid and Cerebral Infarction

ArticleYear
Update of the ULtra-early TRranexamic Acid after Subarachnoid Hemorrhage (ULTRA) trial: statistical analysis plan.
    Trials, 2020, Feb-18, Volume: 21, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Cerebral Infarction; Clinical Trials, Phase II as Topic; Clinical Tr

2020
Antifibrinolytic treatment in subarachnoid hemorrhage.
    The New England journal of medicine, 1984, Aug-16, Volume: 311, Issue:7

    Topics: Cerebral Angiography; Cerebral Infarction; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Do

1984
Outcome of aneurysmal subarachnoid hemorrhage in patients 66 years of age and older.
    Clinical neurology and neurosurgery, 1988, Volume: 90, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Cerebral Infarction; Cyclohexanecarboxylic Acids; Double-Blind

1988

Other Studies

2 other studies available for tranexamic acid and Cerebral Infarction

ArticleYear
Cerebrovascular infarction following bilateral total knee arthroplasty and tranexamic acid administration.
    Acta orthopaedica Belgica, 2013, Volume: 79, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Cerebral Infar

2013
Amount of blood on computed tomography as an independent predictor after aneurysm rupture.
    Stroke, 1993, Volume: 24, Issue:6

    Topics: Age Factors; Aged; Aneurysm, Ruptured; Blood; Cerebral Infarction; Double-Blind Method; Glasgow Coma

1993