tranexamic acid has been researched along with Blunt Injuries in 16 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of systemic prednisolone and topical tranexamic acid (TA) on the rate of rebleeding in patients with macroscopic traumatic hyphema (MTH)." | 9.51 | Systemic prednisolone versus topical tranexamic acid for prevention of rebleeding in patients with traumatic hyphema: A randomized clinical trial. ( Abbaspour, M; Abrishami, M; Bakhtiari, E; Derakhshan, A; Esmaeili, S; Firoozi, J; Zia, MJ, 2022) |
| "The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients." | 9.24 | Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. ( Edwards, P; Joshi, M; Ker, K; Mahmood, A; Prieto, D; Roberts, I; Shakur, H, 2017) |
| " The CRASH-2 trial aimed to determine the effect of the early administration of tranexamic acid on death and transfusion requirement in bleeding trauma patients." | 9.17 | The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. ( Balogun, E; Barnetson, L; Cairns, J; Coats, T; Cook, L; Guerriero, C; Hunt, B; Kawahara, T; Perel, P; Prieto-Merino, D; Ramos, M; Roberts, I; Shakur, H, 2013) |
| "In a population with a high rate of secondary bleeding, TA is more effective than oral prednisolone or no oral treatment in preventing rebleeding among patients with traumatic hyphema." | 9.09 | Comparison of tranexamic acid and prednisolone in the treatment of traumatic hyphema. A randomized clinical trial. ( Jahadi, HR; Rahmani, B, 1999) |
| "To compare the efficacy of systemic prednisolone and topical tranexamic acid (TA) on the rate of rebleeding in patients with macroscopic traumatic hyphema (MTH)." | 5.51 | Systemic prednisolone versus topical tranexamic acid for prevention of rebleeding in patients with traumatic hyphema: A randomized clinical trial. ( Abbaspour, M; Abrishami, M; Bakhtiari, E; Derakhshan, A; Esmaeili, S; Firoozi, J; Zia, MJ, 2022) |
| "The CRASH-2 trial showed that tranexamic acid (TXA) administration reduces mortality in bleeding trauma patients." | 5.24 | Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. ( Edwards, P; Joshi, M; Ker, K; Mahmood, A; Prieto, D; Roberts, I; Shakur, H, 2017) |
| " The CRASH-2 trial aimed to determine the effect of the early administration of tranexamic acid on death and transfusion requirement in bleeding trauma patients." | 5.17 | The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. ( Balogun, E; Barnetson, L; Cairns, J; Coats, T; Cook, L; Guerriero, C; Hunt, B; Kawahara, T; Perel, P; Prieto-Merino, D; Ramos, M; Roberts, I; Shakur, H, 2013) |
| "In a population with a high rate of secondary bleeding, TA is more effective than oral prednisolone or no oral treatment in preventing rebleeding among patients with traumatic hyphema." | 5.09 | Comparison of tranexamic acid and prednisolone in the treatment of traumatic hyphema. A randomized clinical trial. ( Jahadi, HR; Rahmani, B, 1999) |
| " Secondary hemorrhage had no statistical association with age, gender, oral prednisolone, size of hyphema, and retinal damage." | 5.09 | An analysis of risk for secondary hemorrhage in traumatic hyphema. ( Jahadi, HR; Rahmani, B; Rajaeefard, A, 1999) |
| " Although evidence was limited, it appears that people with traumatic hyphema who receive aminocaproic acid or tranexamic acid are less likely to experience secondary hemorrhaging." | 5.01 | Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2019) |
| "Three hundred forty children with nonperforating traumatic hyphema were examined to verify or refute the possible protective action of the antifibrinolytic agent, tranexamic acid, against rebleeding." | 3.67 | Management of traumatic hyphema in children. An analysis of 340 cases. ( Ranta-Kemppainen, L; Tarkkanen, A; Uusitalo, RJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Derakhshan, A | 1 |
| Firoozi, J | 1 |
| Esmaeili, S | 1 |
| Bakhtiari, E | 1 |
| Abbaspour, M | 1 |
| Abrishami, M | 1 |
| Zia, MJ | 1 |
| Burton, H | 1 |
| Mossadegh, S | 1 |
| McCarthy, R | 1 |
| Gharaibeh, A | 1 |
| Savage, HI | 1 |
| Scherer, RW | 1 |
| Goldberg, MF | 1 |
| Lindsley, K | 1 |
| Roberts, I | 2 |
| Shakur, H | 2 |
| Coats, T | 1 |
| Hunt, B | 1 |
| Balogun, E | 1 |
| Barnetson, L | 1 |
| Cook, L | 1 |
| Kawahara, T | 1 |
| Perel, P | 1 |
| Prieto-Merino, D | 1 |
| Ramos, M | 1 |
| Cairns, J | 1 |
| Guerriero, C | 1 |
| David, JS | 1 |
| Godier, A | 1 |
| Dargaud, Y | 1 |
| Inaba, K | 1 |
| Lipsky, AM | 1 |
| Abramovich, A | 1 |
| Nadler, R | 1 |
| Feinstein, U | 1 |
| Shaked, G | 1 |
| Kreiss, Y | 1 |
| Glassberg, E | 1 |
| Bock, A | 1 |
| Tucker, N | 1 |
| Kelher, MR | 1 |
| Khan, SY | 1 |
| Gonzalez, E | 1 |
| Wohlauer, M | 1 |
| Hansen, K | 1 |
| Dzieciatkowska, M | 1 |
| Sauaia, A | 1 |
| Banerjee, A | 1 |
| Moore, EE | 1 |
| Silliman, CC | 1 |
| Zentai, C | 1 |
| van der Meijden, PE | 1 |
| Braunschweig, T | 1 |
| Hueck, N | 1 |
| Honickel, M | 1 |
| Spronk, HM | 1 |
| Rossaint, R | 1 |
| Grottke, O | 1 |
| Edwards, P | 1 |
| Prieto, D | 1 |
| Joshi, M | 1 |
| Mahmood, A | 1 |
| Ker, K | 1 |
| Barrie, J | 1 |
| Jamdar, S | 1 |
| Iniguez, MF | 1 |
| Bouamra, O | 1 |
| Jenks, T | 1 |
| Lecky, F | 1 |
| O'Reilly, DA | 1 |
| Albiani, DA | 1 |
| Hodge, WG | 1 |
| Pan, YI | 1 |
| Urton, TE | 1 |
| Clarke, WN | 1 |
| Stovicek, J | 1 |
| Keil, R | 1 |
| Pálová, S | 1 |
| Lochmannová, J | 1 |
| Klyve, P | 1 |
| Rahmani, B | 2 |
| Jahadi, HR | 2 |
| Rajaeefard, A | 1 |
| Uusitalo, RJ | 1 |
| Ranta-Kemppainen, L | 1 |
| Tarkkanen, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339] | Phase 2 | 0 participants (Actual) | Interventional | 2022-03-31 | Withdrawn (stopped due to Challenges in recruitment) | ||
| Randomized Study on the Topical Application of Tranexamic Acid to Wound Bed for Hemostasis in the Setting Granulating Wounds Following Mohs Micrographic Surgery[NCT04541303] | Early Phase 1 | 62 participants (Anticipated) | Interventional | 2020-10-08 | Recruiting | ||
| The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty[NCT03795649] | 80 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | |||
| A Large Randomised Placebo Controlled Trial Among Trauma Patients With, or at Risk of, Significant Haemorrhage, of the Effects of Antifibrinolytic Treatment on Death and Transfusion Requirement[NCT00375258] | Phase 3 | 20,211 participants (Actual) | Interventional | 2005-05-31 | Completed | ||
| Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880] | Phase 4 | 25 participants (Actual) | Interventional | 2020-09-10 | Active, not recruiting | ||
| Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973] | Phase 3 | 220 participants (Actual) | Interventional | 2018-12-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tranexamic acid and Blunt Injuries
| Article | Year |
|---|---|
Medical interventions for traumatic hyphema.
Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Ch | 2019 |
5 trials available for tranexamic acid and Blunt Injuries
| Article | Year |
|---|---|
Systemic prednisolone versus topical tranexamic acid for prevention of rebleeding in patients with traumatic hyphema: A randomized clinical trial.
Topics: Antifibrinolytic Agents; Eye Injuries; Humans; Hyphema; Intraocular Pressure; Prednisolone; Tranexam | 2022 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Topics: Adult; Antifibrinolytic Agents; Blood Transfusion; Confidence Intervals; Craniocerebral Trauma; Fema | 2013 |
Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms.
Topics: Age Factors; Antifibrinolytic Agents; Blood Pressure; Chi-Square Distribution; Fibrinolysis; Glasgow | 2017 |
Comparison of tranexamic acid and prednisolone in the treatment of traumatic hyphema. A randomized clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifibrinolytic Agents; Child; Child, Preschool; Eye | 1999 |
An analysis of risk for secondary hemorrhage in traumatic hyphema.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifibrinolytic Agents; Child; Child, Preschool; Eye | 1999 |
10 other studies available for tranexamic acid and Blunt Injuries
| Article | Year |
|---|---|
Hockey: a pain in the butt! Isolated superior gluteal artery rupture following blunt pelvic trauma - an unusual case.
Topics: Aneurysm, False; Antifibrinolytic Agents; Buttocks; Computed Tomography Angiography; Embolization, T | 2021 |
Case scenario: management of trauma-induced coagulopathy in a severe blunt trauma patient.
Topics: Accidents, Traffic; Adult; Anticoagulants; Antifibrinolytic Agents; Blood Coagulation Disorders; Ear | 2013 |
Tranexamic acid in the prehospital setting: Israel Defense Forces' initial experience.
Topics: Adult; Antifibrinolytic Agents; Clinical Protocols; Emergency Medical Services; Female; Hemorrhage; | 2014 |
α-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2.
Topics: Acute Lung Injury; Cell Membrane; Endothelial Cells; Flow Cytometry; Humans; Inflammation; Intercell | 2015 |
Hemostatic Therapy Using Tranexamic Acid and Coagulation Factor Concentrates in a Model of Traumatic Liver Injury.
Topics: Abdominal Injuries; Animals; Antifibrinolytic Agents; Blood Coagulation; Blood Coagulation Factors; | 2016 |
Improved outcomes for hepatic trauma in England and Wales over a decade of trauma and hepatobiliary surgery centralisation.
Topics: Adult; Antifibrinolytic Agents; Digestive System Surgical Procedures; Emergency Medicine; England; F | 2018 |
Tranexamic acid in the treatment of pediatric traumatic hyphema.
Topics: Antifibrinolytic Agents; Child; Drug Therapy, Combination; Eye Injuries; Female; Glucocorticoids; Hu | 2008 |
Intestinal lymphangiectasia: a rare cause of gastrointestinal bleeding?
Topics: Adult; Antifibrinolytic Agents; Dietary Fats; Female; Gastrointestinal Hemorrhage; Gastroscopy; Huma | 2007 |
[Contusion of the eyeball. Changes in trauma types and their treatment].
Topics: Accidents, Occupational; Adolescent; Adult; Athletic Injuries; Child; Contusions; Eye Injuries; Fema | 1993 |
Management of traumatic hyphema in children. An analysis of 340 cases.
Topics: Bed Rest; Cataract; Child; Eye Injuries; Female; Humans; Hyphema; Hypnotics and Sedatives; Male; Occ | 1988 |