Page last updated: 2024-11-05

tranexamic acid and Blood Pressure, Low

tranexamic acid has been researched along with Blood Pressure, Low in 8 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery."7.11Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery. ( Abubakirov, M; Aguado, HJ; Alfonsi, P; Amir, M; Astrakov, SV; Ayad, S; Balasubramanian, K; Bangdiwala, SI; Belley-Cote, E; Bhatt, K; Biccard, B; Borges, FK; Chan, MTV; Cheong, CC; Conen, D; Copland, I; de Nadal, M; Devereaux, PJ; Duceppe, E; Efremov, S; Eikelboom, J; Fleischmann, E; Garg, AX; Gross, PL; Guyatt, G; Iglesisas, PP; Jayaram, R; Kirov, M; Kleinlugtenbelt, YV; Kurz, A; Lamy, A; Landoni, G; Leslie, K; Likhvantsev, V; Lomivorotov, VV; Marcucci, M; Martínez Zapata, MJ; McGillion, M; McIntyre, W; Meyhoff, CS; Ofori, SN; Painter, TW; Parlow, JL; Patel, A; Petit, S; Polanczyk, CA; Rao, M; Richards, T; Roshanov, P; Ruetzler, K; Schmartz, D; Sessler, D; Short, TG; Spence, J; Srinathan, S; Stillo, D; Szczeklik, W; Tandon, V; Torres, D; VanHelder, T; Vincent, J; Wang, CY; Wang, MK; Whitlock, RP; Wittmann, M; Wu, WKK; Xavier, D; Yusuf, S, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery."3.11Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery. ( Abubakirov, M; Aguado, HJ; Alfonsi, P; Amir, M; Astrakov, SV; Ayad, S; Balasubramanian, K; Bangdiwala, SI; Belley-Cote, E; Bhatt, K; Biccard, B; Borges, FK; Chan, MTV; Cheong, CC; Conen, D; Copland, I; de Nadal, M; Devereaux, PJ; Duceppe, E; Efremov, S; Eikelboom, J; Fleischmann, E; Garg, AX; Gross, PL; Guyatt, G; Iglesisas, PP; Jayaram, R; Kirov, M; Kleinlugtenbelt, YV; Kurz, A; Lamy, A; Landoni, G; Leslie, K; Likhvantsev, V; Lomivorotov, VV; Marcucci, M; Martínez Zapata, MJ; McGillion, M; McIntyre, W; Meyhoff, CS; Ofori, SN; Painter, TW; Parlow, JL; Patel, A; Petit, S; Polanczyk, CA; Rao, M; Richards, T; Roshanov, P; Ruetzler, K; Schmartz, D; Sessler, D; Short, TG; Spence, J; Srinathan, S; Stillo, D; Szczeklik, W; Tandon, V; Torres, D; VanHelder, T; Vincent, J; Wang, CY; Wang, MK; Whitlock, RP; Wittmann, M; Wu, WKK; Xavier, D; Yusuf, S, 2022)
"Tranexamic acid has been used to reduce blood loss and the subsequent need for transfusion in orthopedic, spinal, and cardiac surgery."2.74The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial. ( Choi, WS; Irwin, MG; Samman, N, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Marcucci, M1
Painter, TW1
Conen, D1
Leslie, K1
Lomivorotov, VV1
Sessler, D1
Chan, MTV1
Borges, FK1
Martínez Zapata, MJ1
Wang, CY1
Xavier, D1
Ofori, SN1
Landoni, G1
Efremov, S1
Kleinlugtenbelt, YV1
Szczeklik, W1
Schmartz, D1
Garg, AX1
Short, TG1
Wittmann, M1
Meyhoff, CS1
Amir, M1
Torres, D1
Patel, A1
Duceppe, E1
Ruetzler, K1
Parlow, JL1
Tandon, V1
Wang, MK1
Fleischmann, E1
Polanczyk, CA1
Jayaram, R1
Astrakov, SV1
Rao, M1
VanHelder, T1
Wu, WKK1
Cheong, CC1
Ayad, S1
Abubakirov, M1
Kirov, M1
Bhatt, K1
de Nadal, M1
Likhvantsev, V1
Iglesisas, PP1
Aguado, HJ1
McGillion, M1
Lamy, A1
Whitlock, RP1
Roshanov, P1
Stillo, D1
Copland, I1
Vincent, J1
Balasubramanian, K1
Bangdiwala, SI1
Biccard, B1
Kurz, A1
Srinathan, S1
Petit, S1
Eikelboom, J1
Richards, T1
Gross, PL1
Alfonsi, P1
Guyatt, G1
Belley-Cote, E1
Spence, J1
McIntyre, W1
Yusuf, S1
Devereaux, PJ1
Wang, HY1
Yuan, MC1
Pei, FX1
Zhou, ZK1
Liao, R1
Farrell, MS1
Kim, WC1
Stein, DM1
Vulliamy, P1
Thaventhiran, AJ1
Davenport, RA1
Kluj, P1
Aleksandrowicz, D1
Machała, W1
Gaszyński, T1
Choi, WS1
Irwin, MG1
Samman, N1
Jansen, JO1
Thomas, R1
Loudon, MA1
Brooks, A1
Annecke, T1
Geisenberger, T1
Kürzl, R1
Penning, R1
Heindl, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PeriOperative ISchemic Evaluation-3 Trial[NCT03505723]Phase 39,535 participants (Actual)Interventional2018-06-27Completed
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for tranexamic acid and Blood Pressure, Low

ArticleYear
Emergency Transfusions.
    Emergency medicine clinics of North America, 2020, Volume: 38, Issue:4

    Topics: Antifibrinolytic Agents; Blood Grouping and Crossmatching; Blood Transfusion; Catheterization, Centr

2020
What's new for trauma haemorrhage management?
    British journal of hospital medicine (London, England : 2005), 2019, May-02, Volume: 80, Issue:5

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Transfusion; Hemorrhage; Hemostatic Tech

2019
[Advanced methods of prehospital bleeding management based on the experience and standards of tactical medicine].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2015, Volume: 39, Issue:231

    Topics: Abdominal Injuries; Amputation, Traumatic; Antifibrinolytic Agents; Emergency Medical Services; Hemo

2015
Damage control resuscitation for patients with major trauma.
    BMJ (Clinical research ed.), 2009, Jun-05, Volume: 338

    Topics: Acidosis; Blood Cells; Blood Coagulation Disorders; Calcium; Factor VIIa; Fibrinogen; Hemostasis; Hu

2009

Trials

2 trials available for tranexamic acid and Blood Pressure, Low

ArticleYear
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery.
    Trials, 2022, Jan-31, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Hypotension; Perioperative Care; Tranexamic A

2022
The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:1

    Topics: Adult; Analysis of Variance; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Fem

2009

Other Studies

2 other studies available for tranexamic acid and Blood Pressure, Low

ArticleYear
Finding the optimal control level of intraoperative blood pressure in no tourniquet primary total knee arthroplasty combine with tranexamic acid: a retrospective cohort study which supports the enhanced recovery strategy.
    Journal of orthopaedic surgery and research, 2020, Aug-25, Volume: 15, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Pressure

2020
Algorithm-based coagulation management of catastrophic amniotic fluid embolism.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:1

    Topics: Acidosis; Adult; Algorithms; Blood Coagulation Factors; Blood Component Transfusion; Cardiovascular

2010