Page last updated: 2024-11-05

tranexamic acid and Blood Loss, Surgical

tranexamic acid has been researched along with Blood Loss, Surgical in 1488 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Blood Loss, Surgical: Loss of blood during a surgical procedure.

Research Excerpts

ExcerptRelevanceReference
"Multiple doses of dexamethasone and tranexamic acid can inhibit postoperative inflammation and reduce fibrinolysis and perioperative blood loss in total knee arthroplasty."9.69Tourniquets can further reduce perioperative blood loss in patients on dexamethasone and tranexamic acid during cemented total knee arthritis: a single-center, double-blind, randomized controlled trial. ( Huang, Q; Jiang, W; Liu, M; Pei, F; Wang, X; Xie, J; Xu, H; Zhou, R; Zhou, Z, 2023)
" The purpose of this study was to assess the safety of tranexamic acid (TXA) utilization with respect to the incidence of deep venous thrombosis (DVT) in hemophiliacs undergoing total knee arthroplasty (TKA)."9.69Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study. ( Guo, JJ; Yu, Z; Zhang, Q; Zhao, L, 2023)
"Patients with non-traumatic epistaxis were evaluated in three treatment groups as topical lidocaine, epinephrine, and TXA."9.51Comparison of the therapeutic efficacy of topical tranexamic acid, epinephrine, and lidocaine in stopping bleeding in non-traumatic epistaxis: a prospective, randomized, double-blind study. ( Ekmekyapar, M; Gur, A; Sahin, L, 2022)
"Based upon Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), the authors collected fully published English literature on the administration of tranexamic acid for patients undergoing intracranial meningioma surgery using the keywords ["tranexamic acid" and "meningioma"] and its synonyms from Cochrane Central Database, the WHO International Clinical Trials Registry Platform (ICTRP), ClinicalTrials."9.41A systematic review and meta-analysis of the effects of tranexamic acid in surgical procedure for intracranial meningioma. ( Chadid, DP; July, J; Quintero-Consuegra, M; Wijaya, JH, 2023)
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."9.41The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."9.41Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"Tranexamic acid (TXA) has been widely used in orthopedic surgery, but its efficacy in adolescent scoliosis (AS) surgery remains unclear in the literature."9.41Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis. ( Chen, K; Gao, Q; Masood, U; Song, Y; Wang, L; Yang, H; Zeng, Z, 2023)
" We included controlled trials, either randomized (RCT) or non-randomized studies of intervention (NRSI) comparing the effects of intravenous tranexamic acid (TXA) treatment with placebo/no treatment on postoperative blood loss, pain VAS score, elbow ROM, and complications, in patients who underwent open or closed elbow arthrolysis surgery."9.41Does tranexamic acid diminish hemorrhage and pain in open elbow arthrolysis? a systematic review and meta-analysis. ( Daliri, M; Ebrahimzadeh, MH; Khayami, A; Moradi, A; Nejat, MH; Sadeghi, M, 2023)
"To conduct the first-ever systematic review and meta-analysis of randomized controlled trials (RCTs) on the antihemorrhagic utility and safety of tranexamic acid (TXA) versus misoprostol for management (prevention and/or treatment) of postpartum hemorrhage (PPH)."9.41Tranexamic acid versus misoprostol for management of postpartum hemorrhage: A systematic review and meta-analysis of randomized controlled trials. ( Abdulmalik, NA; Abu-Zaid, A; Abuzaid, M; Albadawi, MI; Alblewi, H; Albouq, B; Alomar, O; Alsehaimi, SO; Alyousef, A; Baradwan, S; Bukhari, IA; Ghazi, A; Khadawardi, K; Salem, H, 2023)
"Tranexamic acid (TXA) is widely used in surgery for adolescent idiopathic scoliosis (AIS) and has been proved to be efficacious in reducing intraoperative blood loss (IBL) and the transfusion rate."9.41The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial. ( Liu, LM; Song, YM; Wang, L; Wang, LN; Xiu, P; Yang, X; Zhang, Z; Zhou, ZJ, 2021)
"The objective of this study is to determine the efficacy of high-dose versus low-dose tranexamic acid (TXA) in adolescent idiopathic scoliosis (AIS) corrective surgery."9.41Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery. ( Chan, CYW; Chiu, CK; Hasan, MS; Kwan, MK; Ng, CC; Yunus, SN, 2021)
"We aimed to determine the efficacy and safety of multiple doses of intravenous tranexamic acid (IV-TXA) on perioperative blood loss in patients with rheumatoid arthritis (RA) who had undergone primary unilateral total knee arthroplasty (TKA)."9.41Multiple intravenous tranexamic acid doses in total knee arthroplasty in patients with rheumatoid arthritis: a randomized controlled study. ( Gao, CX; Gao, XJ; Kang, BX; Ma, YH; Sun, ST; Xiao, LB; Xie, J; Xu, H; Xu, XR; Zhai, WT; Zhang, J; Zhao, C; Zhong, S, 2021)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."9.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
"To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TXA alone."9.41Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial. ( Dong, Y; Li, Q; Liang, J; Shen, J; Tong, B; Zhao, H, 2021)
"The combined application of tranexamic acid and rivaroxaban significantly reduced the amount of blood loss and the transfusion rate during PLIF surgery and avoided an increase in the probability of thrombosis and the occurrence of epidural haematoma."9.34Combined use of tranexamic acid and rivaroxaban in posterior lumbar interbody fusion safely reduces blood loss and transfusion rates without increasing the risk of thrombosis-a prospective, stratified, randomized, controlled trial. ( Chen, Y; Guan, T; Jiao, G; Li, Y; Liu, D; Liu, H; Meng, C; Sun, Z; Wang, H; Wu, W; Xiao, X; Xue, H; Yue, H; Zhang, L; Zhou, H, 2020)
"This clinical trial is designed to evaluate the effect of multiple-dose tranexamic acid (TXA) on perioperative blood loss in patients with rheumatoid arthritis (RA)."9.34Multiple-dose tranexamic acid for perioperative blood loss in total knee arthroplasty in patients with rheumatoid arthritis:a single-blinded, randomised, parallel-controlled study protocol in China. ( Gao, CX; Kang, BX; Ma, YH; Sun, ST; Xiao, LB; Xie, J; Xu, H; Zhai, WT; Zhang, J; Zhong, S, 2020)
"To investigate the effect of adjunctive intravenous tranexamic acid (TA) on blood loss during cesarean section (CS) in patients with placenta previa undergone bilateral uterine arteryligation (BUAL)."9.30Bilateral uterine artery ligation plus intravenous tranexamic acid during cesarean delivery for placenta previa: a randomized double-blind controlled trial. ( Abbas, AM; Sallam, HF; Shady, NW, 2019)
"We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn."9.24Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery. ( Endo, N; Kohno, T; Ohashi, M; Ohashi, N, 2017)
"To assess the effects of tranexamic acid among patients undergoing cesarean delivery who were at high risk of postpartum hemorrhage."9.22Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery. ( Aneja, A; Hanjoora, VM; Kaur, R; Khanna, M; Sujata, N; Tobin, R, 2016)
"The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)."9.20The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015)
"Preincision administration of 10 mg/kg of tranexamic acid significantly improved the surgical field during cleft palate repair."9.20Evaluation of the Efficacy of Tranexamic Acid on the Surgical Field in Primary Cleft Palate Surgery on Children-A Prospective, Randomized Clinical Study. ( Durga, P; Gunnam, P; Gurajala, I; Raavula, P; Ramachandran, G; Reddy, M; Upputuri, O; Veerabathula, P, 2015)
"This study aimed to evaluate the efficacy and safety of using high-dose intravenous tranexamic acid (TXA) to reduce blood loss in idiopathic scoliosis surgery."9.12The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis. ( Chen, JC; Lin, L; Na, XQ; Qu, QC; Ruan, TY; Shrestha, IK; Si, YY; Tan, M; Tao, JP, 2021)
"The use of tranexamic acid (TXA) is established in the treatment of bleeding, especially of bleeding due to hyperfibrinolysis."9.12[Tranexamic acid for bleeding prophylaxis in orthopedic surgery and trauma-standard or customized therapy?] ( Möhnle, P; Pekrul, I; Schachtner, T; Zwißler, B, 2021)
"Intraoperative administration of tranexamic acid significantly reduces blood loss during spinal surgery in children with scoliosis."9.11Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. ( Bacsik, J; Brustowicz, RM; Sethna, NF; Shapiro, F; Sullivan, LJ; Zurakowski, D, 2005)
"The administration of prophylactic tranexamic acid in patients with scoliosis who are undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements."9.09A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. ( Barrowman, NJ; Hall, L; Murto, K; Neilipovitz, DT; Splinter, WM, 2001)
"The effect of high dose tranexamic acid on blood loss after operations for acute aortic dissection was evaluated."9.08[The effect of intraoperative high-dose tranexamic acid on blood loss after operation for acute aortic dissection]. ( Hirayama, T; Misumi, H; Nakajima, M; Shimamura, Y; Shimokawa, T; Uemura, K; Uesugi, H, 1998)
"Objective To summarize cases of acute myocardial infarction (AMI) after tranexamic acid (TXA) administration."9.05Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports. ( Shao, K; Yao, YT; Yuan, X, 2020)
"To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty."9.01Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019)
"To evaluate the efficacy and safety of tranexamic acid (TXA) in patients with adolescent idiopathic scoliosis undergoing corrective surgery."9.01The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis. ( Cao, K; Lin, N; Lu, H; Wang, B; Zhong, J; Zhou, X, 2019)
"To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty."8.98Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018)
"This meta-analysis aims to assess the efficacy and safety of tranexamic acid for reducing blood loss and transfusion requirements in patients with intertrochanteric fractures."8.95Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of tranexamic acid (TXA) versus placebo after a scoliosis surgery."8.95Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis. ( Xu, BS; Yuan, QM; Zhao, ZH, 2017)
"The aim of this meta-analysis was to assess whether tranexamic acid (TXA) therapy for adult cardiac surgery is associated with an increase in the risk of seizures, and we performed a meta-analysis of randomized controlled trials (RCTs) and non-randomized observational studies."8.95Seizures associated with tranexamic acid for cardiac surgery: a meta-analysis of randomized and non-randomized studies. ( Ando, T; Takagi, H; Umemoto, T, 2017)
"There has been an explosion of interest in the ability of tranexamic acid to reduce morbidity and mortality in surgical and traumatic bleeding."8.91The current place of tranexamic acid in the management of bleeding. ( Hunt, BJ, 2015)
"Intravenous tranexamic acid reduces bleeding in surgery, however, its effect on the risk of thromboembolic events is uncertain and an increased risk remains a theoretical concern."8.89Topical application of tranexamic acid for the reduction of bleeding. ( Beecher, D; Ker, K; Roberts, I, 2013)
"The aim of this study is critically to review the available evidence regarding the use, efficacy and safety of tranexamic acid in the management of hemorrhage during pregnancy and for prevention and treatment of postpartum hemorrhage."8.87Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum. ( Kadir, RA; Peitsidis, P, 2011)
"We conducted a secondary analysis of the MAssive Transfusion in Children (MATIC), a prospectively collected database of children with life-threatening hemorrhage (LTH), and evaluated for risk of adverse events with either antifibrinolytic treatment, epsilon aminocaproic acid (EACA) or tranexamic acid (TXA)."8.31Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children. ( Josephson, CD; Kolodziej, JH; Leeper, CM; Leonard, JC; Spinella, PC; Zenati, MS, 2023)
"To evaluate the effects of administering tranexamic acid (TXA) after cardiopulmonary bypass, instead of after anesthesia induction, on postoperative seizures and blood transfusion requirements."8.12Tranexamic acid after cardiopulmonary bypass does not increase risk of postoperative seizures: a retrospective study. ( Chen, C; Du, L; Liu, J, 2022)
"The utility of tranexamic acid (TXA) in patients with Marfan syndrome (MFS) is uncertain given associated aberrations within the vasculature and clotting cascade."8.12Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome. ( Ikwuezunma, IA; Margalit, A; Sponseller, PD, 2022)
"Previous studies demonstrated the safety of tranexamic acid (TXA) use in cerebral palsy (CP) patients undergoing proximal femoral varus derotational osteotomy (VDRO), but were underpowered to determine if TXA alters transfusion rates or estimated blood loss (EBL)."8.12Tranexamic acid use decreases transfusion rate in children with cerebral palsy undergoing proximal femoral varus derotational osteotomy. ( Andras, L; Compton, E; Goldstein, RY; Kay, RM; Nazareth, A; Shymon, SJ, 2022)
"Background and Objectives: Previous studies regarding tranexamic acid (TXA) in total knee arthroplasty (TKA) investigated only symptomatic deep vein thrombosis (DVT), or did not include high risk patients."8.12Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients. ( An, BK; Joo, YB; Kim, YM; Kwon, ST; Lee, CW; Song, JH, 2022)
"The administration of tranexamic acid (TXA) has been shown to be beneficial in reducing blood loss during surgery for adolescent idiopathic scoliosis (AIS), but optimal dosing has yet to be defined."8.12High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis. ( Bacon, A; Javidan, Y; Klineberg, E; Roberto, R; Stondell, C; Tafoya, S; Taylor, SL; Tumber, S, 2022)
" The purpose of this study was to compare the effects of intra-articular (IA) administration of tranexamic acid (TXA), an anti-fibrinolytic commonly used in TKA, and ALM chondroprotective solution on postoperative inflammation and joint tissue healing in a rat model of knee implant surgery."8.02Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty. ( Biros, E; Dlaska, C; Dobson, GP; Hazratwala, K; Letson, HL; McEwen, P; Morris, JL; Wilkinson, M, 2021)
"This case reminds clinicians that perioperative tranexamic acid administration may increase the risk of thrombosis, which needs focused attention from anesthesiologists."8.02Circulation collapse caused by intracardiac thrombosis associated with tranexamic acid administration: A case report. ( Gu, KP; Huang, CJ; Xie, Q; Yao, YX, 2021)
"Tranexamic acid (TXA) is an antifibrinolytic used for prophylaxis and treatment of acute bleeding."8.02Impact of Obesity on Tranexamic Acid Efficacy in Adult Patients With Major Bleeding. ( Farina, N; Franz, ND; Machado-Aranda, D; Miller, JT, 2021)
"Tranexamic acid (TXA) has gained increasing recognition in plastic surgery as a dependable adjunct capable of minimizing blood loss, ecchymosis, and edema."8.02Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis. ( Banuelos, J; Molinar, VE; Tran, NV; Weissler, JM, 2021)
"In cardiac surgery, use of the antifibrinolytic agent tranexamic acid (TXA) and acute perioperative stroke are both associated with convulsive seizures."8.02Associations of preoperative stroke and tranexamic acid administration with convulsive seizures in valvular open-heart surgery. ( Deutsch, MA; Gummert, JF; Hulde, N; Koster, A; von Dossow, V; Zittermann, A, 2021)
"Previous studies have demonstrated that the use of tranexamic acid (TXA) reduces blood loss and transfusion requirements in children undergoing scoliosis surgery."8.02A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. ( Bronson, WE; Halpern, LM; Kogan, CJ, 2021)
"This study aimed to investigate the effect of intravenous tranexamic acid (TXA) on blood loss and transfusion rates in children who underwent resection and endoprosthetic reconstruction of distal femoral osteosarcomas."8.02Efficacy and Safety of Tranexamic Acid in Resection and Endoprosthetic Reconstruction of Distal Femoral Osteosarcomas in Children: A Retrospective Cohort Study. ( Buyuktopcu, O; Erol, B; Kesimer, MD; Ozturk, O; Polat, M; Sofulu, O, 2021)
"Tranexamic acid (TXA) is an effective agent used for reducing perioperative blood loss and decreasing the potential for postoperative hemarthrosis."7.88Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty. ( Boyle, KK; Nodzo, SR; Pavlesen, S; Ritter, C, 2018)
"To investigate the effectiveness and safety of intravenous tranexamic acid for reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis (TSS)."7.88The efficacy and safety of tranexamic acid in reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis: A retrospective observational study. ( Huang, X; Huang, Y; Liu, T; Qiao, F; Xu, X; Xue, P; Yang, J, 2018)
"Our objective was to quantify blood loss and transfusion requirements for high-dose and low-dose tranexamic acid (TXA) dosing regimens in pediatric patients undergoing spinal fusion for correction of idiopathic scoliosis."7.85High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery. ( Frank, SM; Goobie, SM; Johnson, CC; Johnson, DJ; Nami, N; Sponseller, PD; Wetzler, JA, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic that is widely used to reduce surgical bleeding."7.83Intravenous tranexamic acid for intracerebral meningioma resections: A randomized, parallel-group, non-inferiority trial. ( Li, S; Liu, M; Peng, Y; Sessler, DI; Wu, Y; Yan, X; Yang, J; Zeng, M; Zhang, L; Zhou, D, 2024)
"Use of large dose tranexamic acid routinely seems to be effective and safe in reducing allogenic blood transfusion and blood loss in adolescent idiopathic scoliosis surgery."7.83Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Sui, WY; Yang, JL; Ye, F, 2016)
"We investigated the influence of intraoperative continuous tranexamic acid (TA) infusion on the amount of blood transfusion required in emergency surgery for type A acute aortic dissection."7.81Usefulness of intraoperative continuous infusion of tranexamic acid during emergency surgery for type A acute aortic dissection. ( Ahn, KT; Hirose, K; Ikarashi, J; Iwakura, A; Kusuhara, T; Nakatsuka, D; Yamanaka, K, 2015)
"We describe, for the first time, the use of topical tranexamic acid as an adjunct to traditional methods in the control of bleeding in burns surgery."7.78Use of tranexamic acid to reduce bleeding in burns surgery. ( Brooks, P; Chapman, TW; Tang, YM, 2012)
"A retrospective review of consecutive adult patients undergoing scoliosis correction surgery was performed to compare the effects of aprotinin and tranexamic acid in blood conservation and to define a comprehensive blood conservation strategy for such surgery."7.78Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. ( Ahuja, S; Guha, A; Khurana, A; Pugh, S; Saxena, N, 2012)
"To assess the efficacy and safety of tranexamic acid (TXA) in decreasing operative blood loss and the need for transfusion during posterior spinal fusion for the treatment of idiopathic scoliosis in adolescents."7.78Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? ( Fukuda, K; Hasegawa, J; Iizuka, S; Kaneko, S; Machida, M; Nagoshi, N; Shioda, M; Takemitsu, M; Yagi, M, 2012)
"We compared intraoperative blood loss and blood replacement during spinal fusion surgery for scoliosis in Duchenne muscular dystrophy (DMD) performed with and without the synthetic antifibrinolytic agent tranexamic acid (TXA)."7.74Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis. ( Sethna, NF; Shapiro, F; Zurakowski, D, 2007)
"Tranexamic acid (TXA) has been widely applied in total knee arthroplasty (TKA) to significantly reduce perioperative blood loss and improve knee function recovery in patients after surgery."7.30Effectiveness of different antithrombotic agents in combination with tranexamic acid for venous thromboembolism prophylaxis and blood management after total knee replacement: a prospective randomized study. ( Wang, CC; Wu, T; Zhang, GQ; Zhang, LT; Zhou, LB, 2023)
"No tranexamic acid was administered to the control group."7.30[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study]. ( Hrabálek, L; Jablonský, J; Novák, V; Stejskal, P; Trnka, Š; Wanek, T, 2023)
"Tranexamic acid (TXA) has been proven to prevent thrombolysis and reduce bleeding and blood transfusion requirements in various surgical settings."7.30The effect of tranexamic acid on intraoperative blood loss in patients undergoing brain meningioma resections: Study protocol for a randomized controlled trial. ( Jin, H; Li, M; Li, S; Liu, M; Liu, X; Ma, T; Peng, Y; Wang, J; Wu, Y; Yang, J; Yu, H; Zeng, M; Zhang, L; Zhang, X, 2023)
"The hemostatic effect of tranexamic acid (TXA) combined with carbazochrome sodium sulfonate (CSS) in total hip arthroplasty (THA) has not been determined."7.11Effects of carbazochrome sodium sulfonate combined with tranexamic acid on hemostasis and inflammation during perioperative period of total hip arthroplasty: A randomized controlled trial. ( Kang, P; Liu, Z; Luo, Y; Releken, Y; Yang, D; Yue, Y, 2022)
"Postoperative pneumonia is a major cause of morbidity and mortality following cardiac surgery."7.11Characterisation of Plasma Mitochondrial DNA, MMP-9 and Neutrophil Elastase in Patients Undergoing Coronary Artery Bypass Grafting: Effects of Tranexamic Acid and Postoperative Pneumonia. ( Bain, CR; Draxler, DF; Gruen, RL; Hauser, CJ; Ho, H; Medcalf, RL; Myles, PS; Sandler, N; Smith, JA, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery."7.11Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery. ( Abubakirov, M; Aguado, HJ; Alfonsi, P; Amir, M; Astrakov, SV; Ayad, S; Balasubramanian, K; Bangdiwala, SI; Belley-Cote, E; Bhatt, K; Biccard, B; Borges, FK; Chan, MTV; Cheong, CC; Conen, D; Copland, I; de Nadal, M; Devereaux, PJ; Duceppe, E; Efremov, S; Eikelboom, J; Fleischmann, E; Garg, AX; Gross, PL; Guyatt, G; Iglesisas, PP; Jayaram, R; Kirov, M; Kleinlugtenbelt, YV; Kurz, A; Lamy, A; Landoni, G; Leslie, K; Likhvantsev, V; Lomivorotov, VV; Marcucci, M; Martínez Zapata, MJ; McGillion, M; McIntyre, W; Meyhoff, CS; Ofori, SN; Painter, TW; Parlow, JL; Patel, A; Petit, S; Polanczyk, CA; Rao, M; Richards, T; Roshanov, P; Ruetzler, K; Schmartz, D; Sessler, D; Short, TG; Spence, J; Srinathan, S; Stillo, D; Szczeklik, W; Tandon, V; Torres, D; VanHelder, T; Vincent, J; Wang, CY; Wang, MK; Whitlock, RP; Wittmann, M; Wu, WKK; Xavier, D; Yusuf, S, 2022)
" However, postoperative seizure, as one of the major adverse effects of TXA infusion, has been a concern that restricts its utility in neurosurgery."7.11Safety of intravenous tranexamic acid in patients undergoing supratentorial meningiomas resection: protocol for a randomised, parallel-group, placebo control, non-inferiority trial. ( Dong, J; Li, R; Li, S; Liu, X; Ma, T; Peng, Y; Wang, J; Yan, X; Zeng, M; Zhang, X, 2022)
" The current study aimed to determine whether tranexamic acid (TXA) in combination with pressure dressing reduce the amount of blood loss, the rate of incision-related complications, and the rate of readmission for patients undergoing surgeries to release GMC."7.11Tranexamic acid combined with compression dressing reduces blood loss in gluteal muscle contracture surgery. ( Huang, Q; Huang, Z; Ma, J; Pei, F; Shen, B; Zhou, Z, 2022)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."7.11A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Tranexamic Acid (TXA) has been used in medical and surgical practice to reduce haemorrhage."7.01Tranexamic acid use in meningioma surgery - A systematic review and meta-analysis. ( Bakhsh, A; Brodbelt, AR; Clynch, AL; Gillespie, CS; Islim, AI; Jenkinson, MD; Keshwara, SM; Kumar, S; Mills, SJ; Millward, CP; Mustafa, MA; Richardson, GE; Zakaria, R, 2023)
"Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are concerns about its thromboembolic effects."7.01Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis. ( Cheah, S; Cheong, CC; Mong, SXY; Ng, KT; Tsan, SEH; Viknaswaran, NL; Wang, CY, 2023)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."7.01Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."6.90Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
" Other secondary variables were total blood loss, hidden blood loss, transfusion rate, average hospital stay, complications, adverse events, and mortality."6.90Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"Radical cystectomy for bladder cancer is associated with a high risk of needing red blood cell transfusion."6.87Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial. ( Breau, RH; Bryson, G; Cagiannos, I; Cnossen, S; Fergusson, DA; Kanji, S; Knoll, G; Lavallée, LT; Mallick, R; Momoli, F; Morash, C; Turgeon, A; Witiuk, K; Zarychanski, R, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss."6.87Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial. ( Brustowicz, RM; Emans, JB; Glotzbecker, MP; Goobie, SM; Hedequist, D; Hresko, MT; Karlin, LI; McCann, ME; Sethna, NF; Zurakowski, D, 2018)
"Usually, TXA-associated seizures persist for a few minutes with no progression into status epilepticus."6.82Tranexamic acid-associated fatal status epilepticus in a paediatric non-cardiac surgery: A case report and literature review. ( Aboul-Fotouh, S; Habib, MZ; Hassan, BEE; Magdy, SM, 2022)
" (3) The appropriate, empirically established, dosage and administration patterns of TEA for CDH repair during ECMO seem to be one bolus of 4 mg/kg TEA intravenously 30 minutes before the anticipated CDH repair and a continuous infusion of 1 mg/kg/h TEA during the 24 hours after CDH repair."6.68Surgical repair of congenital diaphragmatic hernia during extracorporeal membrane oxygenation: hemorrhagic complications and the effect of tranexamic acid. ( de Haan, AF; Festen, C; Geven, WB; van der Staak, FH, 1997)
"We failed to observe a difference in infection risk after adjustment for confounders and surgeon differences (hazard ratio [HR] 1."5.91Tranexamic acid is not associated with decreased infection risk after primary shoulder arthroplasty: a cohort study of 9276 patients. ( Chan, PH; Gorbaty, J; McElvany, MD; Prentice, HA; Yian, EH, 2023)
"Bleeding complications are not uncommon after breast reduction surgery, and recently, tranexamic acid (TXA) as an antifibrinolytic agent has been used in various surgical specialties as a way to minimizes such adverse outcomes."5.91The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates. ( Kebede, S; Losken, A; Marxen, T; Om, A, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce blood loss following surgery."5.91Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection. ( Foster, D; Garner, H; Goulding, K; Houdek, M; Sebro, R; Spaulding, AC; Stanborough, R; Wilke, B, 2023)
"Tranexamic acid (TXA) has gained increasing recognition as a valuable pharmacologic agent within plastic surgery."5.72Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty. ( Alsayed, A; Antezana, L; Banuelos, J; Curiel, D; Harless, CA; Kerivan, L; Kuruoglu, D; Martinez-Jorge, J; Nguyen, MT; Sharaf, BA; Tran, NV; Vijayasekaran, A; Weissler, JM, 2022)
"High-dose tranexamic acid is more effective in reducing blood loss and blood transfusion without increasing the risk of postoperative complications."5.69Intraoperative use of tranexamic acid to reduce blood loss during cytoreductive surgery for advanced ovarian cancer: A randomized controlled clinical trial. ( Chai, M; He, Z; Wu, X; Xia, L; Yang, X; Zhang, J, 2023)
"Prophylactic use of tranexamic acid during cesarean delivery did not lead to a significantly lower risk of a composite outcome of maternal death or blood transfusion than placebo."5.69Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery. ( Bailit, JL; Chauhan, SP; Clifton, RG; Dalton, W; Grobman, WA; Gyamfi-Bannerman, C; Longo, M; Macones, GA; Metz, TD; Pacheco, LD; Parry, S; Rood, K; Rouse, DJ; Saade, GR; Salazar, A; Simhan, HN; Thorp, JM; Tita, ATN; Weiner, SJ, 2023)
"Multiple doses of dexamethasone and tranexamic acid can inhibit postoperative inflammation and reduce fibrinolysis and perioperative blood loss in total knee arthroplasty."5.69Tourniquets can further reduce perioperative blood loss in patients on dexamethasone and tranexamic acid during cemented total knee arthritis: a single-center, double-blind, randomized controlled trial. ( Huang, Q; Jiang, W; Liu, M; Pei, F; Wang, X; Xie, J; Xu, H; Zhou, R; Zhou, Z, 2023)
" The purpose of this study was to assess the safety of tranexamic acid (TXA) utilization with respect to the incidence of deep venous thrombosis (DVT) in hemophiliacs undergoing total knee arthroplasty (TKA)."5.69Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study. ( Guo, JJ; Yu, Z; Zhang, Q; Zhao, L, 2023)
" The purpose of this study was to determine if TXA is safe to use in patients with a history of CAD or coronary stents."5.62Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty. ( Rozell, JC; Schwarzkopf, R; Sharan, M; Tang, A; Waren, D; Zak, SG, 2021)
"Tranexamic acid (TXA) has been used extensively to minimize blood loss in cardiac surgery and more recently in orthopedic surgery."5.56Tranexamic acid administration during total joint arthroplasty surgery is not associated with an increased risk of perioperative seizures: a national database analysis. ( Fiasconaro, M; Kirksey, MA; Liu, J; Memtsoudis, SG; Poeran, J; Wilson, LA, 2020)
"This study was carried out to evaluate role of intravenous tranexamic acid (TXA) in reducing blood loss during tangential excision of burns."5.51Effect of single dose intravenous tranexamic acid on blood loss in tangential excision of burn wounds - A double blind randomised controlled trial. ( K S, A; Kumar, P; Sharma, RK; Subair, M, 2022)
"Patients with non-traumatic epistaxis were evaluated in three treatment groups as topical lidocaine, epinephrine, and TXA."5.51Comparison of the therapeutic efficacy of topical tranexamic acid, epinephrine, and lidocaine in stopping bleeding in non-traumatic epistaxis: a prospective, randomized, double-blind study. ( Ekmekyapar, M; Gur, A; Sahin, L, 2022)
"To assess the efficacy and safety of single-dose tranexamic acid on the blood transfusion rate and outcomes of patients with complex kidney stones undergoing percutaneous nephrolithotomy (PCNL)."5.51Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial. ( Batagello, CA; Coelho, RF; Danilovic, A; Marchini, GS; Mazzucchi, E; Miller, AW; Monga, M; Nahas, WC; Srougi, M; Torricelli, FCM; Vicentini, FC, 2022)
"Pediatric craniosynostosis repair with cranial vault reconstructive surgery can be associated with significant blood loss."5.51Ulnar Artery Thrombosis Following Tranexamic Acid Administration for Craniosynostosis Repair. ( Chung, E; Karlberg, HI, 2019)
"The combined use of intraarticular topical TXA with rivaroxaban in patients undergoing TKA is a safe and effective method to reduce blood loss, the need for transfusion, and wound complications without elevating the risk of DVT."5.48Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis. ( Kang, MW; Kim, JI; Kim, YT; Lee, JK; Lee, YM, 2018)
" The best administration route and dosage should be further studied."5.48[Preliminary analysis of the effect of different administration routes of tranexamic acid on blood loss after total hip arthroplasty for female femur neck fractures]. ( Lin, ZQ; Luo, GG; Xie, HF; Yao, JC; Zhang, HZ, 2018)
"Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery."5.46Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion. ( Chiem, J; Ivanova, I; Jimenez, N; Krengel, W; Parker, A, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic agent that can be used to reduce blood loss in total knee arthroplasty (TKA) patients."5.43Intraarticular Administration of Tranexamic Acid is Safe and Effective in Total Knee Arthroplasty Patients at High-Risk for Thromboembolism. ( Chughtai, M; Delanois, RE; Gwam, C; Khlopas, A; Mistry, JB; Mont, MA; Mudaliar, PP; Tangri, V; Thomas, M, 2016)
"Based upon Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), the authors collected fully published English literature on the administration of tranexamic acid for patients undergoing intracranial meningioma surgery using the keywords ["tranexamic acid" and "meningioma"] and its synonyms from Cochrane Central Database, the WHO International Clinical Trials Registry Platform (ICTRP), ClinicalTrials."5.41A systematic review and meta-analysis of the effects of tranexamic acid in surgical procedure for intracranial meningioma. ( Chadid, DP; July, J; Quintero-Consuegra, M; Wijaya, JH, 2023)
"To compare the efficacy of different dosages of intravenous (IV) tranexamic acid (TXA) in the treatment of traumatic hip fractures against that of the control group of no TXA."5.41The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis. ( Bloom, DA; Chapman, CB; Konda, SR; Lin, CC; Manzi, JE; Mojica, ES; Telgheder, ZL, 2023)
"Tranexamic acid is a cost-effective intervention for the prevention of postpartum hemorrhage among women who undergo cesarean delivery, but the evidence to support its use is conflicting."5.41Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials. ( Ahmad, AB; Ayyan, M; Azeem, S; Cheema, HA; Ehsan, M; Hussain, A; Laganà, AS; Mikuš, M; Nashwan, AJ; Shahid, A, 2023)
"In this meta-analysis, the combination of TXA and DEX has positive impacts on the usage of oxycodone and metoclopramide, postoperative range of motion, postoperative nausea and vomiting and reduces the length of hospital stay."5.41Effects of combined dexamethasone and tranexamic acid in lower limb total arthroplasty: a systematic review and meta-analysis of randomized clinical trials. ( Gopal Subramaniam, A; Hau, R; Tan, TK, 2023)
"Meta-analyses on the use of tranexamic acid (TXA) in intertrochanteric fractures have shown inconsistent results due to variations in inclusion criteria and clinical heterogeneity."5.41Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis. ( Fan, X; Wu, J; Yuan, X; Zhang, J; Zheng, Y, 2023)
"Tranexamic acid (TXA) has been widely used in orthopedic surgery, but its efficacy in adolescent scoliosis (AS) surgery remains unclear in the literature."5.41Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis. ( Chen, K; Gao, Q; Masood, U; Song, Y; Wang, L; Yang, H; Zeng, Z, 2023)
" We included controlled trials, either randomized (RCT) or non-randomized studies of intervention (NRSI) comparing the effects of intravenous tranexamic acid (TXA) treatment with placebo/no treatment on postoperative blood loss, pain VAS score, elbow ROM, and complications, in patients who underwent open or closed elbow arthrolysis surgery."5.41Does tranexamic acid diminish hemorrhage and pain in open elbow arthrolysis? a systematic review and meta-analysis. ( Daliri, M; Ebrahimzadeh, MH; Khayami, A; Moradi, A; Nejat, MH; Sadeghi, M, 2023)
"To conduct the first-ever systematic review and meta-analysis of randomized controlled trials (RCTs) on the antihemorrhagic utility and safety of tranexamic acid (TXA) versus misoprostol for management (prevention and/or treatment) of postpartum hemorrhage (PPH)."5.41Tranexamic acid versus misoprostol for management of postpartum hemorrhage: A systematic review and meta-analysis of randomized controlled trials. ( Abdulmalik, NA; Abu-Zaid, A; Abuzaid, M; Albadawi, MI; Alblewi, H; Albouq, B; Alomar, O; Alsehaimi, SO; Alyousef, A; Baradwan, S; Bukhari, IA; Ghazi, A; Khadawardi, K; Salem, H, 2023)
"Tranexamic acid (TXA) is widely used in surgery for adolescent idiopathic scoliosis (AIS) and has been proved to be efficacious in reducing intraoperative blood loss (IBL) and the transfusion rate."5.41The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial. ( Liu, LM; Song, YM; Wang, L; Wang, LN; Xiu, P; Yang, X; Zhang, Z; Zhou, ZJ, 2021)
"The objective of this study is to determine the efficacy of high-dose versus low-dose tranexamic acid (TXA) in adolescent idiopathic scoliosis (AIS) corrective surgery."5.41Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery. ( Chan, CYW; Chiu, CK; Hasan, MS; Kwan, MK; Ng, CC; Yunus, SN, 2021)
"We aimed to determine the efficacy and safety of multiple doses of intravenous tranexamic acid (IV-TXA) on perioperative blood loss in patients with rheumatoid arthritis (RA) who had undergone primary unilateral total knee arthroplasty (TKA)."5.41Multiple intravenous tranexamic acid doses in total knee arthroplasty in patients with rheumatoid arthritis: a randomized controlled study. ( Gao, CX; Gao, XJ; Kang, BX; Ma, YH; Sun, ST; Xiao, LB; Xie, J; Xu, H; Xu, XR; Zhai, WT; Zhang, J; Zhao, C; Zhong, S, 2021)
"To investigate the efficacy and safety of intravenous combined with topical administration of tranexamic acid (TXA) in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures by a prospective controlled trial."5.41[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures]. ( Gong, D; Gou, Y; Li, H; Li, W; Liu, D; Tang, X; Wang, N; Wu, Y; Zhang, Y, 2021)
" Tranexamic acid (TXA) is most commonly given as a single preoperative dose only and is often withheld from patients with a history of thromboembolic disease as they are perceived to be "high-risk" with respect to postoperative venous thromboembolism (VTE)."5.41Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total hip arthroplasty: results of a randomized controlled trial (TRAC-24). ( Bell, J; Benson, G; Beverland, D; Bryce, L; Campbell, C; Dorman, A; Gardner, E; Hill, JC; Hogg, R; Magill, P; Martin, U; McFarland, M, 2021)
"To indicate whether combined topical and intravenous (IV) administration of tranexamic acid (TXA) could further reduce the blood loss after surgery for adolescent idiopathic scoliosis (AIS) compared with IV-TXA alone."5.41Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial. ( Dong, Y; Li, Q; Liang, J; Shen, J; Tong, B; Zhao, H, 2021)
"Tranexamic acid is an antifibrinolytic drug."5.39Tranexamic acid and thrombosis. ( , 2013)
"Postoperative seizures occurred significantly more frequently in TXA patients (7."5.37Seizures after open heart surgery: comparison of ε-aminocaproic acid and tranexamic acid. ( Breuer, T; Gertler, R; Knorr, J; Lange, R; Macguill, M; Martin, K; Tassani, P; Wiesner, G, 2011)
"All patients with seizures did not have permanent neurological abnormalities."5.36High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients. ( Burt, C; Chu, M; Falter, F; Granton, J; Murkin, JM; Young, B, 2010)
"The aim of this study was to evaluate the effects of a high initial-dose (60 mg/kg) intravenous tranexamic acid (IV-TXA) on fibrinolysis and inflammation after total knee arthroplasty (TKA)."5.34The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial. ( Huang, Q; Huang, W; Lei, YT; Pei, FX; Xie, JW, 2020)
"The combined application of tranexamic acid and rivaroxaban significantly reduced the amount of blood loss and the transfusion rate during PLIF surgery and avoided an increase in the probability of thrombosis and the occurrence of epidural haematoma."5.34Combined use of tranexamic acid and rivaroxaban in posterior lumbar interbody fusion safely reduces blood loss and transfusion rates without increasing the risk of thrombosis-a prospective, stratified, randomized, controlled trial. ( Chen, Y; Guan, T; Jiao, G; Li, Y; Liu, D; Liu, H; Meng, C; Sun, Z; Wang, H; Wu, W; Xiao, X; Xue, H; Yue, H; Zhang, L; Zhou, H, 2020)
"This clinical trial is designed to evaluate the effect of multiple-dose tranexamic acid (TXA) on perioperative blood loss in patients with rheumatoid arthritis (RA)."5.34Multiple-dose tranexamic acid for perioperative blood loss in total knee arthroplasty in patients with rheumatoid arthritis:a single-blinded, randomised, parallel-controlled study protocol in China. ( Gao, CX; Kang, BX; Ma, YH; Sun, ST; Xiao, LB; Xie, J; Xu, H; Zhai, WT; Zhang, J; Zhong, S, 2020)
"An initial retrospective study suggested that tranexamic acid (TXA) administration increased the incidence of seizures in paediatric patients undergoing cardiac surgery."5.30Safety and efficacy of tranexamic acid in paediatric cardiac surgery: study protocol for a double-blind randomised controlled trial. ( Hu, S; Hua, Z; Jia, Y; Li, S; Liu, J; Ran, J; Shi, J; Wang, R; Wang, X; Wang, Y; Yan, F; Yan, J; Yuan, S; Zhang, Y; Zhang, Z; Zhao, Y; Zheng, Z, 2019)
"We examined the blood conserving effect of tranexamic acid in total hip arthroplasty using the direct anterior approach with enoxaparin as deep vein thrombosis (DVT) chemoprophylaxis, and whether this translates to an effect on functional outcomes in the perioperative period."5.30OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial. ( Duggan, J; Duncan, S; Fraval, A; Murray, T; Tirosh, O; Tran, P, 2019)
"To investigate the effect of adjunctive intravenous tranexamic acid (TA) on blood loss during cesarean section (CS) in patients with placenta previa undergone bilateral uterine arteryligation (BUAL)."5.30Bilateral uterine artery ligation plus intravenous tranexamic acid during cesarean delivery for placenta previa: a randomized double-blind controlled trial. ( Abbas, AM; Sallam, HF; Shady, NW, 2019)
"The objective of this study was to ascertain whether combined intravenous (IV) and intra-articular (IA) administration of tranexamic acid (TXA) is beneficial for reducing blood loss and the prevalence of deep venous thrombosis (DVT) in primary simultaneous bilateral total knee arthroplasty compared with IV only administration of TXA."5.27Comparative Efficacy of Intravenous With Intra-articular Versus Intravenous Only Administration of Tranexamic Acid to Reduce Blood Loss in Knee Arthroplasty. ( Kim, JS; Kim, YH; Pandey, K; Park, JW, 2018)
"The aim of this randomized double-blind study was to evaluate the efficacy of Tranexamic acid (TXA) on intraoperative bleeding, postoperative eyelid edema, and postoperative periorbital ecchymosis in rhinoplasty."5.24Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study. ( Chavoshzadeh, MA; Ghavimi, MA; Ghoreishizadeh, A; Taheri Talesh, K; Zarandi, A, 2017)
"Systemic administration of TXA can effectively reduce the postoperative blood loss which results in lower rate of transfusion requirement and wound hematoma in minimally invasive TKA patients when rivaroxaban is used for thromboprophylaxis."5.24The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial. ( Chen, B; Huang, CC; Kuo, FC; Lin, PC; Wang, JW; Yen, SH, 2017)
"We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn."5.24Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery. ( Endo, N; Kohno, T; Ohashi, M; Ohashi, N, 2017)
"Compared with intravenous application, topical application of tranexamic acid could also effectively reduce total blood loss and hidden blood loss, postoperative blood transfusion rate in primary total hip arthroplasty, while does not increase the risk of DVT."5.22[Comparison of different modes of using tranexamic acid administration on reducing hidden blood loss in total hip arthroplasty]. ( Chen, XJ; Ni, JR; Wang, LX, 2016)
"To evaluate the efficacy of tranexamic acid (TA) in decreasing blood loss during and after open myomectomy for patients with 3 or more uterine fibroids."5.22Efficacy of Tranexamic Acid on Myomectomy-Associated Blood Loss in Patients With Multiple Myomas: A Randomized Controlled Clinical Trial. ( Ahmed, MR; Dardeer, HH; Farhan, RE; Shaaban, MM, 2016)
"To assess the effects of tranexamic acid among patients undergoing cesarean delivery who were at high risk of postpartum hemorrhage."5.22Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery. ( Aneja, A; Hanjoora, VM; Kaur, R; Khanna, M; Sujata, N; Tobin, R, 2016)
" The use of tranexamic acid to control surgical bleeding and aspirin for venous thromboembolism prophylaxis has gained popularity."5.22Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial. ( Barksdale, LC; Calvo, C; McNamara, CA; Patel, PD; Suarez, JC; Szubski, CR, 2016)
"The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)."5.20The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015)
"Preincision administration of 10 mg/kg of tranexamic acid significantly improved the surgical field during cleft palate repair."5.20Evaluation of the Efficacy of Tranexamic Acid on the Surgical Field in Primary Cleft Palate Surgery on Children-A Prospective, Randomized Clinical Study. ( Durga, P; Gunnam, P; Gurajala, I; Raavula, P; Ramachandran, G; Reddy, M; Upputuri, O; Veerabathula, P, 2015)
" The primary aim of this study was to determine the efficacy of intraoperative tranexamic acid, epsilon-aminocaproic acid, and placebo at reducing perioperative blood loss and the transfusion rate in patients with adolescent idiopathic scoliosis undergoing posterior spinal arthrodesis."5.19The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. ( Boenigk, K; Diefenbach, C; Dryer, J; Errico, T; Hoelscher, C; Huncke, T; Lonner, BS; Peters, A; Verma, K, 2014)
"There was no statistically significant reduction in bleeding volume with the use of tranexamic acid (mean ± standard deviation, 135."5.16Tranexamic acid in adenotonsillectomy in children: a double-blind randomized clinical trial. ( Brum, MR; Castro, SF; Lima, LH; Lubianca Neto, JF; Machado, GM; Miura, MS, 2012)
"Tranexamic acid (TXA) is one of the measures indicated to reduce bleeding and the need for volume replacement."5.12Tranexamic acid in Neurosurgery: a controversy indication-review. ( Costa E Silva, LT; da Silva Brito, J; de Faria, JL; de Souza, NB; Figueiredo, EG; Kilesse, CTSM; Pereira, CU; Rabelo, NN, 2021)
"This study aimed to evaluate the efficacy and safety of using high-dose intravenous tranexamic acid (TXA) to reduce blood loss in idiopathic scoliosis surgery."5.12The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis. ( Chen, JC; Lin, L; Na, XQ; Qu, QC; Ruan, TY; Shrestha, IK; Si, YY; Tan, M; Tao, JP, 2021)
"The use of tranexamic acid (TXA) is established in the treatment of bleeding, especially of bleeding due to hyperfibrinolysis."5.12[Tranexamic acid for bleeding prophylaxis in orthopedic surgery and trauma-standard or customized therapy?] ( Möhnle, P; Pekrul, I; Schachtner, T; Zwißler, B, 2021)
"Tranexamic acid is an efficacious and safe pharmacological-based blood conservation technique in the management of clinically significant hemorrhage."5.12Tranexamic acid: current use in obstetrics, major orthopedic, and trauma surgery. ( George, RB; Hanley, CM; Jerath, A; Saliba, C; Wong, J; Yee, DA, 2021)
"Intraoperative administration of tranexamic acid significantly reduces blood loss during spinal surgery in children with scoliosis."5.11Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. ( Bacsik, J; Brustowicz, RM; Sethna, NF; Shapiro, F; Sullivan, LJ; Zurakowski, D, 2005)
"The administration of prophylactic tranexamic acid in patients with scoliosis who are undergoing posterior spinal fusion surgery has the potential to reduce perioperative blood transfusion requirements."5.09A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. ( Barrowman, NJ; Hall, L; Murto, K; Neilipovitz, DT; Splinter, WM, 2001)
"The effect of high dose tranexamic acid on blood loss after operations for acute aortic dissection was evaluated."5.08[The effect of intraoperative high-dose tranexamic acid on blood loss after operation for acute aortic dissection]. ( Hirayama, T; Misumi, H; Nakajima, M; Shimamura, Y; Shimokawa, T; Uemura, K; Uesugi, H, 1998)
" Tranexamic acid (TXA) is one of the most commonly used and widely researched antifibrinolytic agents; its role in postpartum hemorrhage, menorrhagia, trauma-associated hemorrhage, and surgical bleeding has been well defined."5.05The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. ( Al-Samkari, H; Cai, J; DeLoughery, TG; Olson, S; Raghunathan, V; Ribkoff, J; Shatzel, JJ, 2020)
"Objective To summarize cases of acute myocardial infarction (AMI) after tranexamic acid (TXA) administration."5.05Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports. ( Shao, K; Yao, YT; Yuan, X, 2020)
"To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty."5.01Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019)
"To evaluate the efficacy and safety of tranexamic acid (TXA) in patients with adolescent idiopathic scoliosis undergoing corrective surgery."5.01The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis. ( Cao, K; Lin, N; Lu, H; Wang, B; Zhong, J; Zhou, X, 2019)
"To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty."4.98Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018)
"This meta-analysis aims to assess the efficacy and safety of tranexamic acid for reducing blood loss and transfusion requirements in patients with intertrochanteric fractures."4.95Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials. ( Wang, W; Yu, J, 2017)
"The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of tranexamic acid (TXA) versus placebo after a scoliosis surgery."4.95Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis. ( Xu, BS; Yuan, QM; Zhao, ZH, 2017)
"The aim of this meta-analysis was to assess whether tranexamic acid (TXA) therapy for adult cardiac surgery is associated with an increase in the risk of seizures, and we performed a meta-analysis of randomized controlled trials (RCTs) and non-randomized observational studies."4.95Seizures associated with tranexamic acid for cardiac surgery: a meta-analysis of randomized and non-randomized studies. ( Ando, T; Takagi, H; Umemoto, T, 2017)
"There has been an explosion of interest in the ability of tranexamic acid to reduce morbidity and mortality in surgical and traumatic bleeding."4.91The current place of tranexamic acid in the management of bleeding. ( Hunt, BJ, 2015)
"This systematic review was undertaken to answer three specific questions relating to the clinical values of tranexamic acid (TNA) in total knee arthroplasty (TKA): (1) Whether there are differences in blood-saving effects between the systemic and topical administrations; (2) Whether blood-saving effects of TNA differ by doses and timings of administration; and (3) Whether the use of TNA is safe at all reported doses, timings, and routes of administration with respect to the incidences of symptomatic deep-vein thrombosis (DVT) and pulmonary embolism (PE)."4.90Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review. ( Chang, CB; Kim, TK; Koh, IJ, 2014)
" The aim of this study was to review the literature on the use of lysine analogs to prevent bleeding and blood transfusion during pelvic surgery."4.90The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis. ( Beck, A; Breau, RH; Buenaventura, C; Cagiannos, I; Cowan, J; Fergusson, DA; Knoll, G; Kokolo, MB; Momoli, F; Morash, C; Niznick, N; Punjani, N; Ruzicka, M; Schachkina, S; Tinmouth, A; Xie, HY, 2014)
"Intravenous tranexamic acid reduces bleeding in surgery, however, its effect on the risk of thromboembolic events is uncertain and an increased risk remains a theoretical concern."4.89Topical application of tranexamic acid for the reduction of bleeding. ( Beecher, D; Ker, K; Roberts, I, 2013)
"Tranexamic acid safely reduces mortality in bleeding trauma patients without increasing the risk of adverse events."4.88Antifibrinolytic drugs for acute traumatic injury. ( Coats, T; Ker, K; Roberts, I; Shakur, H, 2012)
"The aim of this study is critically to review the available evidence regarding the use, efficacy and safety of tranexamic acid in the management of hemorrhage during pregnancy and for prevention and treatment of postpartum hemorrhage."4.87Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum. ( Kadir, RA; Peitsidis, P, 2011)
"A systematic review of the literature was conducted to identify all randomized controlled trials of aprotinin, tranexamic acid, and aminocaproic acid involving children undergoing cardiac or scoliosis surgery."4.85The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis. ( Bollen, CW; Jansen, NJ; Schouten, AN; Schouten, ES; Turner, NM; van de Pol, AC, 2009)
"Tranexamic acid (TXA) has been widely utilized to reduce blood loss and allogeneic transfusions in patients who undergo lower limb arthroplasty."4.40Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis. ( Choe, H; Imanishi, K; Inaba, Y; Kamono, E; Kobayashi, N; Kumagai, K; Takagawa, S; Yukizawa, Y, 2023)
" Two multivariable logistic regression models, for postoperative anemia (hemoglobin < 10 g/dL) and allogeneic blood transfusion included 8 variables: age, sex, body mass index, preoperative hemoglobin level, tranexamic acid total dose, American Society of Anesthesiologists level, operative time, and drain use."4.31Predicting Postoperative Anemia and Blood Transfusion Following Total Knee Arthroplasty. ( Ast, MP; Chalmers, BP; Della Valle, AG; Kolin, DA; Landy, DC; Lyman, S, 2023)
"We conducted a secondary analysis of the MAssive Transfusion in Children (MATIC), a prospectively collected database of children with life-threatening hemorrhage (LTH), and evaluated for risk of adverse events with either antifibrinolytic treatment, epsilon aminocaproic acid (EACA) or tranexamic acid (TXA)."4.31Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children. ( Josephson, CD; Kolodziej, JH; Leeper, CM; Leonard, JC; Spinella, PC; Zenati, MS, 2023)
"The use of tranexamic acid (TXA) in posterior lumbar interbody fusion (PLIF) surgery is believed to be beneficial for reducing intraoperative blood loss, postoperative drainage volume (PDV), and length of hospital stay (LOS)."4.31Postoperative clinical outcomes with and without short-term intravenous tranexamic acid after posterior lumbar interbody fusion: A prospective cohort study. ( Ji, X; Shi, L; Tian, F; Wang, X, 2023)
"To evaluate the effects of administering tranexamic acid (TXA) after cardiopulmonary bypass, instead of after anesthesia induction, on postoperative seizures and blood transfusion requirements."4.12Tranexamic acid after cardiopulmonary bypass does not increase risk of postoperative seizures: a retrospective study. ( Chen, C; Du, L; Liu, J, 2022)
"The utility of tranexamic acid (TXA) in patients with Marfan syndrome (MFS) is uncertain given associated aberrations within the vasculature and clotting cascade."4.12Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome. ( Ikwuezunma, IA; Margalit, A; Sponseller, PD, 2022)
"Previous studies demonstrated the safety of tranexamic acid (TXA) use in cerebral palsy (CP) patients undergoing proximal femoral varus derotational osteotomy (VDRO), but were underpowered to determine if TXA alters transfusion rates or estimated blood loss (EBL)."4.12Tranexamic acid use decreases transfusion rate in children with cerebral palsy undergoing proximal femoral varus derotational osteotomy. ( Andras, L; Compton, E; Goldstein, RY; Kay, RM; Nazareth, A; Shymon, SJ, 2022)
"Treatment with tranexamic acid (TxA) significantly reduces maternal death due to postpartum hemorrhage."4.12The effect of prophylactic use of tranexamic acid for cesarean section. ( Binyamin, Y; Erez, O; Frank, D; Frenkel, A; Gruzman, I; Heesen, M; Ioscovich, A; Lerman, S; Orbach-Zinger, S; Zlotnik, A, 2022)
"Tranexamic acid (TXA) has become a widely used antifibrinolytic drug for reducing bleeding in surgery."4.12Safety and efficacy of intravenous or topical tranexamic acid administration in surgery: a protocol for a systematic review and network meta-analysis. ( Han, R; Liang, F; Wang, X; Yu, Y, 2022)
"This multicenter international experience of pediatric craniofacial surgery reports no increase in seizures or thromboembolic events in those that received antifibrinolytics (tranexamic acid and epsilon-aminocaproic acid) versus those that did not."4.12Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group. ( Benzon, HA; Goobie, SM; King, MR; Nelson, O; Pérez-Pradilla, C; Staffa, SJ; Stricker, PA, 2022)
"Background and Objectives: Previous studies regarding tranexamic acid (TXA) in total knee arthroplasty (TKA) investigated only symptomatic deep vein thrombosis (DVT), or did not include high risk patients."4.12Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients. ( An, BK; Joo, YB; Kim, YM; Kwon, ST; Lee, CW; Song, JH, 2022)
"The administration of tranexamic acid (TXA) has been shown to be beneficial in reducing blood loss during surgery for adolescent idiopathic scoliosis (AIS), but optimal dosing has yet to be defined."4.12High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis. ( Bacon, A; Javidan, Y; Klineberg, E; Roberto, R; Stondell, C; Tafoya, S; Taylor, SL; Tumber, S, 2022)
"To determine whether locally injected tranexamic acid (TXA) used in the surgical treatment of fragility hip fractures can lower transfusion rates without increasing the risk of complications."4.12Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review. ( Davis, S; Kumar, M; Shearier, E; Solomito, MJ; Witmer, D, 2022)
" The PBM protocol consisted of epoetin (EPO) alfa therapy prescribed by the surgeon, routine administration of tranexamic acid (TXA), an avascular approach to the hip and postoperative prophylaxis of thromboembolism."4.02Application of an adjusted patient blood management protocol in patients undergoing elective total hip arthroplasty: towards a zero-percent transfusion rate in renal patients-results from an observational cohort study. ( Fennema, P; Hourlier, H, 2021)
" The purpose of this study was to compare the effects of intra-articular (IA) administration of tranexamic acid (TXA), an anti-fibrinolytic commonly used in TKA, and ALM chondroprotective solution on postoperative inflammation and joint tissue healing in a rat model of knee implant surgery."4.02Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty. ( Biros, E; Dlaska, C; Dobson, GP; Hazratwala, K; Letson, HL; McEwen, P; Morris, JL; Wilkinson, M, 2021)
"This case reminds clinicians that perioperative tranexamic acid administration may increase the risk of thrombosis, which needs focused attention from anesthesiologists."4.02Circulation collapse caused by intracardiac thrombosis associated with tranexamic acid administration: A case report. ( Gu, KP; Huang, CJ; Xie, Q; Yao, YX, 2021)
"Tranexamic acid (TXA) is an antifibrinolytic used for prophylaxis and treatment of acute bleeding."4.02Impact of Obesity on Tranexamic Acid Efficacy in Adult Patients With Major Bleeding. ( Farina, N; Franz, ND; Machado-Aranda, D; Miller, JT, 2021)
"Tranexamic acid (TXA) has gained increasing recognition in plastic surgery as a dependable adjunct capable of minimizing blood loss, ecchymosis, and edema."4.02Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis. ( Banuelos, J; Molinar, VE; Tran, NV; Weissler, JM, 2021)
"The aim of this pre and post interventional study looks at the effects of intravenous administration of tranexamic acid on induction for elderly patients undergoing hemiarthroplasty or intramedullary nail fixation for hip fractures."4.02The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role? ( Chakravarty, D; Guhan, B; Kanthasamy, S; Parker, MJ, 2021)
"In cardiac surgery, use of the antifibrinolytic agent tranexamic acid (TXA) and acute perioperative stroke are both associated with convulsive seizures."4.02Associations of preoperative stroke and tranexamic acid administration with convulsive seizures in valvular open-heart surgery. ( Deutsch, MA; Gummert, JF; Hulde, N; Koster, A; von Dossow, V; Zittermann, A, 2021)
"Previous studies have demonstrated that the use of tranexamic acid (TXA) reduces blood loss and transfusion requirements in children undergoing scoliosis surgery."4.02A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. ( Bronson, WE; Halpern, LM; Kogan, CJ, 2021)
"This study aimed to investigate the effect of intravenous tranexamic acid (TXA) on blood loss and transfusion rates in children who underwent resection and endoprosthetic reconstruction of distal femoral osteosarcomas."4.02Efficacy and Safety of Tranexamic Acid in Resection and Endoprosthetic Reconstruction of Distal Femoral Osteosarcomas in Children: A Retrospective Cohort Study. ( Buyuktopcu, O; Erol, B; Kesimer, MD; Ozturk, O; Polat, M; Sofulu, O, 2021)
"The specific method and dose of tranexamic acid (TXA) topically applied for intertrochanteric fractures have not been well established."4.02Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA. ( He, J; Huang, T; Wei, H; Xia, M; Xian, S; Xiao, Q; Xu, W, 2021)
" A standard blood management protocol that consisted of hypotensive anesthesia, local and systemic administration of tranexamic acid (TXA) and intraoperative cell salvage was applied to all patients."3.96Does tourniquet use decrease blood loss following primary total knee arthroplasty in Jehovah's Witness patients? ( Çıtak, M; Gehrke, T; Köse, Ö; Levent, A; Linke, P, 2020)
"We investigated the clinical application of auricular point sticking (APS) combined with tranexamic acid in perioperative hemostasis in elderly patients with intertrochanteric fractures of the femur."3.91Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur. ( Er, Z; Yin, C; Zhang, J, 2019)
"Geriatric hip fracture patients are particularly susceptible to blood loss and venous thromboembolism (VTE) during hemiarthroplasty, yet relatively few studies have examined the safety and efficacy of tranexamic acid (TXA) in these patients."3.91Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study. ( Chen, G; Hu, Q; Huang, Q; Pei, F; Xie, J; Zhou, Z, 2019)
"Antifibrinolytics such as tranexamic acid reduce operative blood loss and blood product transfusion requirements in patients undergoing surgical correction of scoliosis."3.88Effect of Tranexamic Acid on Blood Loss, D-Dimer, and Fibrinogen Kinetics in Adult Spinal Deformity Surgery. ( Edwards, A; Herodes, M; Leveque, JA; Pong, RP; Sethi, RK; Wright, AK; Yanamadala, V, 2018)
"Tranexamic acid (TXA) is an effective agent used for reducing perioperative blood loss and decreasing the potential for postoperative hemarthrosis."3.88Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty. ( Boyle, KK; Nodzo, SR; Pavlesen, S; Ritter, C, 2018)
"To investigate the effectiveness and safety of intravenous tranexamic acid for reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis (TSS)."3.88The efficacy and safety of tranexamic acid in reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis: A retrospective observational study. ( Huang, X; Huang, Y; Liu, T; Qiao, F; Xu, X; Xue, P; Yang, J, 2018)
"Our objective was to quantify blood loss and transfusion requirements for high-dose and low-dose tranexamic acid (TXA) dosing regimens in pediatric patients undergoing spinal fusion for correction of idiopathic scoliosis."3.85High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery. ( Frank, SM; Goobie, SM; Johnson, CC; Johnson, DJ; Nami, N; Sponseller, PD; Wetzler, JA, 2017)
" Tranexamic acid (TA), an anti-fibrinolytic agent, has been shown to reduce peri-operative blood loss without increasing the risk of myocardial infarction (MI); however, no large study has examined the association between TA treatment and post-CABG myonecrosis."3.85Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery. ( Alexander, JH; Carrier, M; Lopes, RD; Merrill, PD; Podgoreanu, M; Tardif, JC; van Diepen, S, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic that is widely used to reduce surgical bleeding."3.83Intravenous tranexamic acid for intracerebral meningioma resections: A randomized, parallel-group, non-inferiority trial. ( Li, S; Liu, M; Peng, Y; Sessler, DI; Wu, Y; Yan, X; Yang, J; Zeng, M; Zhang, L; Zhou, D, 2024)
"Tranexamic acid is significantly less expensive than FE or EPO as a treatment option for total joint arthroplasty patients presenting with preoperative anemia."3.83Cost Analysis of Tranexamic Acid in Anemic Total Joint Arthroplasty Patients. ( Ani, F; Phan, DL; Schwarzkopf, R, 2016)
"Use of large dose tranexamic acid routinely seems to be effective and safe in reducing allogenic blood transfusion and blood loss in adolescent idiopathic scoliosis surgery."3.83Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Sui, WY; Yang, JL; Ye, F, 2016)
"We investigated the influence of intraoperative continuous tranexamic acid (TA) infusion on the amount of blood transfusion required in emergency surgery for type A acute aortic dissection."3.81Usefulness of intraoperative continuous infusion of tranexamic acid during emergency surgery for type A acute aortic dissection. ( Ahn, KT; Hirose, K; Ikarashi, J; Iwakura, A; Kusuhara, T; Nakatsuka, D; Yamanaka, K, 2015)
"The aim of this study was to compare transfusion requirements in patients before and after the introduction of tranexamic acid as standard in patients undergoing spinal surgery for idiopathic scoliosis in a national orthopaedic hospital."3.81Eliminating the use of allogeneic blood products in adolescent idiopathic scoliosis surgery. ( Berney, MJ; Connolly, P; Dawson, PH; Lui, DF; Phillips, M, 2015)
"We describe, for the first time, the use of topical tranexamic acid as an adjunct to traditional methods in the control of bleeding in burns surgery."3.78Use of tranexamic acid to reduce bleeding in burns surgery. ( Brooks, P; Chapman, TW; Tang, YM, 2012)
"A retrospective review of consecutive adult patients undergoing scoliosis correction surgery was performed to compare the effects of aprotinin and tranexamic acid in blood conservation and to define a comprehensive blood conservation strategy for such surgery."3.78Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. ( Ahuja, S; Guha, A; Khurana, A; Pugh, S; Saxena, N, 2012)
"To assess the efficacy and safety of tranexamic acid (TXA) in decreasing operative blood loss and the need for transfusion during posterior spinal fusion for the treatment of idiopathic scoliosis in adolescents."3.78Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? ( Fukuda, K; Hasegawa, J; Iizuka, S; Kaneko, S; Machida, M; Nagoshi, N; Shioda, M; Takemitsu, M; Yagi, M, 2012)
"Sequential cohort study analysing hemoglobin titers, transfusion rates, and the occurrence of venous thromboembolism in patients undergoing hip and knee replacements with and without the administration of tranexamic acid at the time of induction."3.78The routine use of tranexamic acid in hip and knee replacements. ( Chegini, S; Kucheria, R; Lobban, C; Panchmatia, JR; Shah, G; Smallman, JM; Stapleton, C, 2012)
" Postoperatively, a higher incidence of seizures in the first 48 hours was seen with tranexamic acid compared with aprotinin (11% versus 4%, p = 0."3.76Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients. ( Berman, M; Cardone, D; Dunning, J; Gerrard, C; Jenkins, D; Klein, A; Sharples, L; Tsui, S; Vuylsteke, A, 2010)
"Factor VIII:C, epsilon amino-caproic acid or tranexamic acid are prophylactic agents used in preventing hemorrhage pre-operatively in patients with hemophilia A."3.75Acute myocardial infarction in a patient with hemophilia A and factor V Leiden mutation. ( Günaldi, M; Helvaci, A; Kiskaç, M; Küçükkaya, RD; Yildirim, ND, 2009)
"We compared intraoperative blood loss and blood replacement during spinal fusion surgery for scoliosis in Duchenne muscular dystrophy (DMD) performed with and without the synthetic antifibrinolytic agent tranexamic acid (TXA)."3.74Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis. ( Sethna, NF; Shapiro, F; Zurakowski, D, 2007)
"The use of rFIX, rFVIIa, erythropoetin, iron, and tranexamic acid before, during and after scoliosis surgery may be a viable and safe option for hemophilia patients with inhibitors, who refuse blood products."3.74[A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery]. ( Ansermino, M; Chau, A; Purdy, R; Tredwell, S; Wu, J, 2008)
"Knee arthritis is the primary cause of disability in middle-aged and older adults."3.30Value of Tranexamic Acid and Progressive Nursing in Accelerating Postoperative Rehabilitation After Total Knee Arthroplasty. ( Li, L; Liu, G; Pan, H; Wang, F; Wang, J; Zheng, S, 2023)
"Tranexamic acid is a drug thought to reduce blood loss."3.30Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial. ( Aoba, T; Ebata, T; Hayashi, D; Hiramatsu, K; Ishii, K; Kinoshita, F; Kurumiya, Y; Kuwatsuka, Y; Maeda, A; Minami, T; Natsume, S; Okuno, M; Sato, F; Seita, K; Shimizu, Y; Sugawara, G; Yamaguchi, R; Yokoyama, Y; Yonekawa, Y, 2023)
"Tranexamic acid (TXA) has been widely applied in total knee arthroplasty (TKA) to significantly reduce perioperative blood loss and improve knee function recovery in patients after surgery."3.30Effectiveness of different antithrombotic agents in combination with tranexamic acid for venous thromboembolism prophylaxis and blood management after total knee replacement: a prospective randomized study. ( Wang, CC; Wu, T; Zhang, GQ; Zhang, LT; Zhou, LB, 2023)
"Tranexamic acid (TXA) has been shown to reduce intraoperative blood loss and improve the visual field."3.30Tranexamic acid does not significantly lower postoperative bleeding after endoscopic sinus and nasal surgery. ( Chan, E; Hwang, PH; Khanwalkar, A; Kim, D; Ma, Y; Nayak, JV; Patel, ZM; Roozdar, P, 2023)
"Tranexamic acid (TXA) has been shown to be effective in reducing blood loss for patients undergoing THA, but few studies focus on its alleviation of postoperative local pain symptoms."3.30Topical use of tranexamic acid can reduce opioid consumption compared with intravenous use for patients undergoing primary total hip arthroplasty: a prospective randomized controlled trial. ( Jiang, Z; Shen, L; Wang, Q; Xu, W, 2023)
"No tranexamic acid was administered to the control group."3.30[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study]. ( Hrabálek, L; Jablonský, J; Novák, V; Stejskal, P; Trnka, Š; Wanek, T, 2023)
"To evaluate the efficacy and safety of perioperative cryotherapy combined with intra-articular injection of tranexamic acid (TXA) in total knee arthroplasty (TKA) and explore a new strategy of enhanced recovery after TKA."3.30Efficacy of perioperative cryotherapy combined with intra-articular injection of tranexamic acid in total knee arthroplasty. ( Huang, W; Huang, X; Li, F; Liu, W; Shi, W; Yin, D, 2023)
"However, uterine fibroids are highly vascular tumors and, consequently, extremely susceptible to problems from myomectomy-related hemorrhage."3.30Oxytocin versus a combination of tranexamic acid and ethamsylate in reducing intraoperative bleeding during abdominal myomectomy: a randomized clinical trial. ( Abd-ElGawad, M; Abdel-Hakam, F; Abdelaziz, DFM; Abdelhamed, SA; Abdelmonem, H; Abdou, AM; Afiffi, IK; Bosilah, AH; Eldesouky, E; Elhalim, AEMA; Ellaban, M; Elrashedy, AA; Elsayed, HGA; Elsror, AGA; Farag, E; Kamel, MA; Marai, AAE; Marie, H; Mohammed, A; Shaaban, A, 2023)
"Tranexamic acid (TXA) has been proven to prevent thrombolysis and reduce bleeding and blood transfusion requirements in various surgical settings."3.30The effect of tranexamic acid on intraoperative blood loss in patients undergoing brain meningioma resections: Study protocol for a randomized controlled trial. ( Jin, H; Li, M; Li, S; Liu, M; Liu, X; Ma, T; Peng, Y; Wang, J; Wu, Y; Yang, J; Yu, H; Zeng, M; Zhang, L; Zhang, X, 2023)
"This study aimed to evaluate the effect of temperature intervention combined with tranexamic acid (TXA) on perioperative blood loss during spinal fusion and accelerated rehabilitation."3.30The efficacy of temperature intervention combined with tranexamic acid in reducing blood loss and accelerating recovery during spinal fusion. ( Huang, X; Huang, Y; Li, F; Liang, B; Yin, D, 2023)
"Tranexamic acid has been found to be effective in reducing peri-operative blood loss and is widely used across surgical specialties including orthopaedic surgery."3.11Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions. ( Ajiboye, LO; Arojuraye, SA; Ibrahim, SS; James, JA; Jatto, HI; Ramat, AM; Shodipo, OM; Toluse, AM, 2022)
"The hemostatic effect of tranexamic acid (TXA) combined with carbazochrome sodium sulfonate (CSS) in total hip arthroplasty (THA) has not been determined."3.11Effects of carbazochrome sodium sulfonate combined with tranexamic acid on hemostasis and inflammation during perioperative period of total hip arthroplasty: A randomized controlled trial. ( Kang, P; Liu, Z; Luo, Y; Releken, Y; Yang, D; Yue, Y, 2022)
"Postoperative pneumonia is a major cause of morbidity and mortality following cardiac surgery."3.11Characterisation of Plasma Mitochondrial DNA, MMP-9 and Neutrophil Elastase in Patients Undergoing Coronary Artery Bypass Grafting: Effects of Tranexamic Acid and Postoperative Pneumonia. ( Bain, CR; Draxler, DF; Gruen, RL; Hauser, CJ; Ho, H; Medcalf, RL; Myles, PS; Sandler, N; Smith, JA, 2022)
"The primary outcome was postoperative blood loss, and the secondary outcomes were postoperative PRC transfusion and complications."3.11Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial. ( Atthakomol, P; Maethungkul, R; Murakami, H; Phanphaisarn, A; Phinyo, P; Sangsin, A, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery."3.11Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery. ( Abubakirov, M; Aguado, HJ; Alfonsi, P; Amir, M; Astrakov, SV; Ayad, S; Balasubramanian, K; Bangdiwala, SI; Belley-Cote, E; Bhatt, K; Biccard, B; Borges, FK; Chan, MTV; Cheong, CC; Conen, D; Copland, I; de Nadal, M; Devereaux, PJ; Duceppe, E; Efremov, S; Eikelboom, J; Fleischmann, E; Garg, AX; Gross, PL; Guyatt, G; Iglesisas, PP; Jayaram, R; Kirov, M; Kleinlugtenbelt, YV; Kurz, A; Lamy, A; Landoni, G; Leslie, K; Likhvantsev, V; Lomivorotov, VV; Marcucci, M; Martínez Zapata, MJ; McGillion, M; McIntyre, W; Meyhoff, CS; Ofori, SN; Painter, TW; Parlow, JL; Patel, A; Petit, S; Polanczyk, CA; Rao, M; Richards, T; Roshanov, P; Ruetzler, K; Schmartz, D; Sessler, D; Short, TG; Spence, J; Srinathan, S; Stillo, D; Szczeklik, W; Tandon, V; Torres, D; VanHelder, T; Vincent, J; Wang, CY; Wang, MK; Whitlock, RP; Wittmann, M; Wu, WKK; Xavier, D; Yusuf, S, 2022)
" However, postoperative seizure, as one of the major adverse effects of TXA infusion, has been a concern that restricts its utility in neurosurgery."3.11Safety of intravenous tranexamic acid in patients undergoing supratentorial meningiomas resection: protocol for a randomised, parallel-group, placebo control, non-inferiority trial. ( Dong, J; Li, R; Li, S; Liu, X; Ma, T; Peng, Y; Wang, J; Yan, X; Zeng, M; Zhang, X, 2022)
" There were no serious adverse events associated with the interventions in this study."3.11Safety and efficacy of aprotinin versus tranexamic acid for reducing absolute blood loss and transfusion in pediatric patients undergoing craniosynostosis surgery: a randomized, double-blind, three-arm controlled trial. ( Dabbagh Ohadi, MA; Ebrahim Soltani, A; Ebrahim Soltani, Z; Habibi, Z; Hanaei, S; Khademi, S; Maroufi, SF; Nejat, F; Tayebi Meybodi, K; Yaghmaei, B, 2022)
" The current study aimed to determine whether tranexamic acid (TXA) in combination with pressure dressing reduce the amount of blood loss, the rate of incision-related complications, and the rate of readmission for patients undergoing surgeries to release GMC."3.11Tranexamic acid combined with compression dressing reduces blood loss in gluteal muscle contracture surgery. ( Huang, Q; Huang, Z; Ma, J; Pei, F; Shen, B; Zhou, Z, 2022)
"Preoperative TXA is safe and effective in reducing blood loss during and after high-risk CD."3.11Safety and efficacy of preoperative tranexamic acid in reducing intraoperative and postoperative blood loss in high-risk women undergoing cesarean delivery: a randomized controlled trial. ( Al-Asmar, A; Al-Mohamady, M; El Mahy, M; Maged, AM; Rund, NMA; Shalaby, MA, 2022)
"Tranexamic acid is a good choice to reduce blood loss during this type of surgery."3.11Is intravenous tranexamic acid effective in reduction of blood loss during pelvic and acetabular surgery? ( El-Deeb, YM; Sharaby, MMF, 2022)
"Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic surgery."3.11Randomized, controlled trial of two tranexamic acid dosing protocols in adult spinal deformity surgery. ( Clohisy, JCF; Dafrawy, MHE; Frazier, E; Kelly, MP; Lenke, LG; Wolfe, RC, 2022)
"Tranexamic acid is a lysine synthetic derivate that inhibits fibrinolysis and diminishes the bleeding by blocking the five lysine-binding sites for plasminogen."3.11Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial. ( Bayter, JE; Cala, L; Cardenas-Camarena, L; Domínguez-Millan, R; Duran, H; Hoyos, AE; Lopez, A; Mogollon, IR; Perez, M; Talleri, G, 2022)
" DISCUSSION Consensus on optimal TXA dosing regime in primary hip and knee arthroplasties is still missing."3.11Comparison of Intravenous and Topical Tranexamic Acid in Total Joint Arthroplasty. ( Masaryk, J; Melus, V; Steno, B; Vidan, J, 2022)
"Tranexamic acid (TXA) has been shown to reduce intraoperative bleeding and the need for post-operative allogenic blood transfusion requirement in surgery."3.11A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study. ( Ekinci, M; Ersin, M; Günen, E; Kocazeybek, E; Ok, M; Sırma, SÖ; Yılmaz, M, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent that competitively inhibits the conversion of plasminogen to plasmin, thus preventing the binding and degradation of fibrin."3.11Efficacy and Safety of Tranexamic Acid for the Control of Surgical Bleeding in Patients Under Liposuction. ( Álvarez-Trejo, HJ; Bonilla-Catalán, PV; de Andrea, GT; Dorado-Hernández, E; Fierro-Rodríguez, DA; García-Valenzuela, SE; Jiménez-Pavón, KE; Medina-Quintana, VM; Morfin-Meza, KE; Ramos-Maciel, J; Rodríguez-García, FA; Romero-Algara, E; Sánchez-Peña, MA; Torres-Salazar, QL; Villarreal-Salgado, JL, 2022)
"Tranexamic acid (TXA) has shown significant reductions in blood loss and transfusion rates in total knee arthroplasty (TKA)."3.01Multimodal Peri-articular Injection with Tranexamic Acid can reduce postoperative blood loss versus Intravenous Tranexamic Acid in Total Knee Arthroplasty: A Randomized Controlled Trial. ( Lin, J; Peng, HM; Qian, WW; Wang, W; Wang, WD; Weng, XS, 2021)
"Tranexamic acid was used systemically by IV application (15mg/kg) in IV group, locally in the surgical field (2g) in local group as well as combined systemic and local together in combined group."3.01The efficacy, safety, and cost-effectives of combined administration of Intravenous and Local Tranexamic Acid in the management of Patients Undergoing Primary Total Hip Arthroplasty: A prospective, blinded and randomized clinical study. ( Çaylak, R; Örs, Ç, 2021)
"Tranexamic acid (TXA) has been studied extensively during the last 5-8 years."3.01Tranexamic Acid: When is It Indicated in Orthopaedic Surgery? ( Viberg, B, 2023)
"Osteoporotic hip fractures are a major health problem in developed countries."3.01Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis. ( Leverett, GD; Marriott, A, 2023)
"Surgical correction of craniosynostosis can involve significant blood loss."3.01Optimizing Blood Loss and Management in Craniosynostosis Surgery: A Systematic Review of Outcomes Over the Last 40 Years. ( Coombs, DM; Knackstedt, R; Patel, N, 2023)
"Tranexamic acid (TXA) has been considered effective in preventing anemia in total hip arthroplasty, but its role in hemiarthroplasty is debated."3.01Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. ( Augustinus, S; Gardenbroek, TJ; Goslings, JC; Mulders, MAM, 2023)
"Tranexamic acid (TXA) has been found to reduce mortality and blood transfusion in surgical and trauma patients."3.01Is tranexamic acid associated with decreased need for blood transfusion in percutaneous nephrolithotomy: a systematic review and meta-analysis. ( Devana, SK; Kumar, S; Prasad, S; Sharma, G; Sharma, S, 2023)
"Tranexamic Acid (TXA) has been used in medical and surgical practice to reduce haemorrhage."3.01Tranexamic acid use in meningioma surgery - A systematic review and meta-analysis. ( Bakhsh, A; Brodbelt, AR; Clynch, AL; Gillespie, CS; Islim, AI; Jenkinson, MD; Keshwara, SM; Kumar, S; Mills, SJ; Millward, CP; Mustafa, MA; Richardson, GE; Zakaria, R, 2023)
"Tranexamic acid (TXA) has drawn growing interest over the last decade for its benefit in optimizing post-operative bleeding, yet its role in bariatric surgery is poorly understood."3.01Role of Tranexamic Acid (TXA) in Preventing Bleeding Following Sleeve Gastrectomy: a Systematic Review and Meta-analysis. ( Karmali, S; Koloszvari, N; Kung, J; Mocanu, V; Neville, A; Verhoeff, K; Walsh, C; Wilson, H, 2023)
"Its role in reducing postoperative blood loss in breast surgery remains unclear."3.01The Effects of Tranexamic Acid in Breast Surgery: A Systematic Review and Meta-Analysis. ( Huynh, MNQ; McRae, MC; McRae, MH; Voineskos, S; Wong, CR, 2023)
"Intraoperative and postoperative blood loss is a major risk in head and neck (H&N) surgery."3.01A systematic review on the efficacy of tranexamic acid in head and neck surgery. ( Coulson, C; Jamshaid, M; Jamshaid, W; Muzaffar, J; Nieto, H; Sharma, N, 2023)
"Tranexamic acid (TXA) is an anti-fibrinolytic that has been shown to reduce surgical blood losses; however, its use in burn surgery is not well established."3.01Tranexamic acid in burn surgery: A systematic review and meta-analysis. ( Boctor, MJ; Fijany, AJ; Gandhi, RR; Givechian, KB; Olsson, SE; Pekarev, M; Zago, I, 2023)
"Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are concerns about its thromboembolic effects."3.01Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis. ( Cheah, S; Cheong, CC; Mong, SXY; Ng, KT; Tsan, SEH; Viknaswaran, NL; Wang, CY, 2023)
"Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip or knee arthroplasty."3.01Efficacy and safety of single- and double-dose intravenous tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis. ( Cheng, QH; Guo, HZ; Yang, X; Yang, YZ; Zhang, AR; Zhang, ZZ, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug associated with reduced blood loss in a range of surgical specialties, including neurosurgery, orthopedic surgery, and cardiac surgery."3.01Systematic review and meta-analysis of topical tranexamic acid in spine surgery. ( Ambati, VS; Chan, AK; Chou, D; Izima, C; Sampath, SG; Tang, AJ, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic agent shown to decrease intraoperative bleeding, reduce transfusions, and improve outcomes across multiple specialties."3.01Effects of Intravenous Tranexamic Acid During Rhytidectomy: A Randomized, Controlled, Double-Blind Pilot Study. ( Alloju, LM; Cohen, JC; Glasgold, MJ; Glasgold, RA, 2021)
"This study aimed to evaluate the optimal dosage of topical tranexamic acid (TXA) considering the efficacy and safety for controlling bleeding after total knee arthroplasty (TKA)."3.01Optimal dose of topical tranexamic acid considering efficacy and safety in total knee arthroplasty: a randomized controlled study. ( Han, HS; Kim, JK; Lee, DY; Lee, MC; Park, JY; Ro, DH, 2021)
"Tranexamic acid (TXA) has been widely used in hip and knee arthroplasty to decrease perioperative blood loss."3.01A single dose of tranexamic acid reduces blood loss after reverse and anatomic shoulder arthroplasty: a randomized controlled trial. ( Borner, B; Cass, B; Cunningham, G; Hughes, J; Mattern, O; Smith, MM; Taha, ME; Young, AA, 2021)
"Tranexamic acid (TXA) has become a routine part of perioperative care in TKAs."3.01Prospective, randomised, controlled study on the efficacy and safety of different strategies of tranexamic acid with total blood loss, blood transfusion rate and thrombogenic biomarkers in total knee arthroplasty: study protocol. ( Ding, D; He, J; Jin, Q; Jin, Y; Wang, F; Wang, Z; Yang, H; Yang, K; Yang, Y; Zhao, X, 2021)
"Tranexamic acid is a fibrinolysis suppressor that is used for a variety of bleeding control procedures such as hematuria, surgery bleeding, and trauma caused bleeding."3.01The Effects of Tranexamic Acid on Bleeding Control During and after Percutaneous Nephrolithotomy (PCNL): A Randomized Clinical Trial. ( Abedi, F; Farshid, S; Modresi, P; Mokhtari, MR, 2021)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective orthopedic surgery."3.01Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study. ( Cheong, Y; Costain, D; Elder, G; Fera, L; Fraser, B; Kelly, A; Slagel, B, 2021)
"Tranexamic acid (TXA) has been widely used to prevent excessive blood loss perioperatively."2.94Comparison of hemocoagulase atrox versus tranexamic acid used in primary total knee arthroplasty: A randomized controlled trial. ( Lin, Y; Qin, JZ; Shi, L; Wang, SJ; Xia, C; Zhao, HH; Zheng, XP, 2020)
"Tranexamic acid (TXA) has been shown to be effective in reducing blood loss after total knee replacement."2.94Topical tranexamic acid in cemented primary total knee arthroplasty without tourniquet: a prospective randomized study. ( Bustamante Suarez de Puga, D; Martínez Gimenez, E; Mas Martinez, J; Morales Santias, M; Sanz-Reig, J; Verdu Román, C, 2020)
"Tranexamic acid is a synthetic lysine derivative with antifibrinolytic activity used in other surgical disciplines to reduce blood loss during surgery."2.94Intraoperative tranexamic acid to decrease blood loss during myomectomy: a randomized, double-blind, placebo-controlled trial. ( Maasen, MS; Marfori, CQ; Moawad, G; Opoku-Anane, J; Robinson, JK; Vargas, MV, 2020)
"However, there was significantly lower postoperative blood loss with TXA (29."2.94Tranexamic acid for the Latarjet procedure: a randomized controlled trial. ( Hurley, ET; Lim Fat, D; Mullett, H; Pauzenberger, L, 2020)
"Tranexamic acid (TXA) has been widely used in hip and knee arthroplasty to reduce perioperative blood loss and blood transfusion, but the dosage and efficacy of TXA in posterior lumbar spinal surgery are not fully clear."2.94Two Doses of Tranexamic Acid Reduce Blood Loss in Primary Posterior Lumbar Fusion Surgery: A Randomized-controlled Trial. ( Guo, K; Li, D; Li, H; Shi, Q; Wu, J; Zheng, X; Zhu, X, 2020)
"Tranexamic acid (TXA) is an antifibrinolytic agent that has been used to reduce blood loss in orthopedic surgery."2.94Randomized prospective evaluation of the use of tranexamic acid and effects on blood loss for proximal humeral fracture surgery. ( Cuff, DJ; Gorman, RA; Simon, P, 2020)
"Deep venous thrombosis (DVT) and pulmonary embolism (PE) events were monitored and recorded."2.94Combined use of intravenous and topical tranexamic acid efficiently reduces blood loss in patients aged over 60 operated with a 2-level lumbar fusion. ( Bai, T; Huang, Y; Li, J; Liu, Y; Wang, L, 2020)
"Tranexamic acid (TXA) has been shown to reduce blood loss and transfusion requirements in patients undergoing orthopaedic surgery."2.94Intravenous tranexamic acid reduces blood loss and transfusion requirements after periacetabular osteotomy. ( DelPizzo, K; Dodwell, E; Levack, AE; McLawhorn, AS; Nguyen, J; Sink, E, 2020)
"Tranexamic acid (TXA) is an antifibrinolytic agent, which reduces bleeding in numerous scenarios, however, its prophylactic use in mitigating post-TBLB bleeding has not been investigated."2.94Prophylactic use of tranexamic acid for prevention of bleeding during transbronchial lung biopsies - A randomized, double-blind, placebo-controlled trial. ( Abu Rmeileh, A; Abutbul, A; Berkman, N; Cohen Goichman, P; Fridlender, ZG; Huszti, E; Kuint, R; Levy, L; Shriki, O, 2020)
"The purpose of this multicenter, randomized trial was to determine the optimal dosing regimen of tranexamic acid (TXA) to minimize perioperative blood loss in revision total hip arthroplasty."2.94The Optimal Dosing Regimen for Tranexamic Acid in Revision Total Hip Arthroplasty: A Multicenter Randomized Clinical Trial. ( Abdel, MP; Culvern, C; Della Valle, CJ; Fillingham, YA; Malkani, AL; Nahhas, C; Nam, D; Padgett, DE; Schwarzkopf, R; Sershon, RA; Vail, TP, 2020)
" There was no evidence of any serious side effect of tranexamic acid."2.94Safety and Efficacy of Using Tranexamic Acid at the Beginning of Robotic-Assisted Radical Prostatectomy in a Double-Blind Prospective Randomized Pilot Study. ( Balík, M; Broďák, M; Čečka, F; Hušek, P; Košina, J, 2020)
"A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group in which patients (75."2.90Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial. ( Huang, Y; Jiang, LF; Wu, LD; Xu, NW; Zhang, JJ; Zhang, Y; Zhou, D; Zhou, XD, 2019)
"Tranexamic acid (TXA) has long been used to reduce blood loss associated with total knee arthroplasty (TKA)."2.90Comparison of oral vs. combined topical/intravenous/oral tranexamic acid in the prevention of blood loss in total knee arthroplasty: A randomised clinical trial. ( Bernaitis, N; Dare, W; King, L; Randle, R, 2019)
"Uterine fibroids are the commonest tumour of the female genital tract; about one third are symptomatic and require management."2.90Adjunctive use of tranexamic acid to tourniquet in reducing haemorrhage during abdominal myomectomy - A randomized controlled trial. ( Abdul, IF; Adesina, KT; Amadu, MB; Olarinoye, AO; Omokanye, LO, 2019)
"Tranexamic acid appears to be an effective haemostat in endoscopic ear surgery, thus improving surgical field visualisation, especially during manipulation of the external auditory canal soft tissues."2.90Does tranexamic acid improve intra-operative visualisation in endoscopic ear surgery? A double-blind, randomised, controlled trial. ( Das, A; Ghosh, D; Kumar, S; Mitra, S; Sengupta, A, 2019)
"Tranexamic acid was reported to reduce bleeding in patients undergoing percutaneous nephrolithotomy (PCNL)."2.90Re-evaluation of the efficacy of tranexamic acid in reducing blood loss in percutaneous nephrolithotomy: a randomized clinical trial. ( Gholipour, F; Kazemi, R; Mohammadi Sichani, M; Nouri-Mahdavi, K, 2019)
" Other secondary variables were total blood loss, hidden blood loss, transfusion rate, average hospital stay, complications, adverse events, and mortality."2.90Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study). ( Aguilera, X; Bosch, A; Camacho-Carrasco, P; Castillón, P; González, JC; Hernández, JA; Jordan, M; Martínez-Zapata, MJ; Mora, JM; Prat-Fabregat, S; Rodriguez-Arias, A; Ruiz, L; Salomó, M, 2019)
"Tranexamic acid (TXA) reduces surgical blood loss and alleviates inflammatory response in total hip arthroplasty."2.90Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial. ( He, C; Li, Q; Luo, ZY; Pei, FX; Wang, D; Yang, Y; Zeng, WN; Zhou, ZK, 2019)
"Tranexamic acid (TXA) is an efficient antifibrinolytic agent, but the mode and timing of its administration remain controversial."2.90A randomized, double-blind, placebo-controlled trial on the efficacy of tranexamic acid combined with rivaroxaban thromboprophylaxis in reducing blood loss after primary cementless total hip arthroplasty. ( Baynat, C; Clavé, A; Danguy des Déserts, M; Gatineau, F; Gérard, R; Lacroix, J; Mottier, D, 2019)
"Tranexamic acid (TXA) has been routinely delivered in multisegmental spinal decompression and bone graft fusion surgeries with satisfactory outcomes in minimizing gross blood loss and transfusion demands."2.90Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries (TARGETS): study protocol for a prospective, randomized, double-blind, non-inferiority trial. ( Chen, X; Huang, Y; Hui, S; Li, S; Mahmood, F; Ren, Z; Sheng, L; Tao, L; Xu, D; Zhuang, Q, 2019)
"Tranexamic acid (TXA) has been widely used in total knee arthroplasty (TKA) for blood loss reduction."2.90Intra-Articular Tranexamic Acid Mitigates Blood Loss and Morphine Use After Total Knee Arthroplasty. A Randomized Controlled Trial. ( Galassi, M; Laoruengthana, A; Pongpirul, K; Rasamimongkol, S; Rattanaprichavej, P; Weerakul, S, 2019)
"Eligible patients with trochanteric fractures surgically treated by dynamic hip screw and proximal anti-rotating intramedullary nail between March 2016 and October 2017 were enrolled in the study."2.90Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial. ( Chen, F; Jiang, Z; Li, M; Zhu, X, 2019)
"Additional reduction of postoperative blood loss may further reduce exposure to allogeneic blood products."2.90Reduced perioperative blood loss in children undergoing craniosynostosis surgery using prolonged tranexamic acid infusion: a randomised trial. ( D'Amore Lindholm, A; Fenger-Eriksen, C; Hvas, AM; Juul, N; Krogh, L; Nørholt, SE; Rasmussen, M; Tarpgaard, M; von Oettingen, G, 2019)
"Tranexamic acid (TXA) is proven to reduce blood loss following total knee arthroplasty (TKA), but there are limited data on the impact of similar dosing regimens in revision TKA."2.902019 Mark Coventry Award: A multicentre randomized clinical trial of tranexamic acid in revision total knee arthroplasty: does the dosing regimen matter?. ( Abdel, MP; Bini, S; Calkins, TE; Culvern, C; Darrith, B; Della Valle, CJ; Fillingham, YA; Malkani, AL; Padgett, DE; Schwarzkopf, R; Sershon, RA, 2019)
"Outcomes assessed are intraoperative and postoperative blood loss, hematocrit, allogenic blood transfusion, and deep vein thrombosis (DVT), postoperatively."2.87Effectiveness and Safety of Batroxobin, Tranexamic Acid and a Combination in Reduction of Blood Loss in Lumbar Spinal Fusion Surgery. ( Dumpa, SR; Kanna, RM; Nagabhushan, RM; Shanmuganathan, R; Shetty, AP; Subramanian, B, 2018)
"Tranexamic acid (TXA) has demonstrated efficacy in reducing blood loss, reduction in hemoglobin, and blood transfusion requirements in primary total hip arthroplasty (THA)."2.87Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study. ( Luo, ZY; Pei, FX; Wang, D; Wang, HY; Zhou, K; Zhou, ZK, 2018)
"The purpose of this study was to compare the effects of three dosage regimens of intravenous tranexamic acid and normal saline placebo on blood loss and the requirement for transfusion during bimaxillary osteotomy."2.87The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study. ( Apipan, B; Narainthonsaenee, T; Rummasak, D, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic agent, decreasing blood loss in hip arthroplasty."2.87Is tranexamic acid exposure related to blood loss in hip arthroplasty? A pharmacokinetic-pharmacodynamic study. ( Delavenne, X; Hodin, S; Lanoiselée, J; Ollier, E; Zufferey, PJ, 2018)
" TA efficiency and optimal dosage in haemorrhagic caesarean section (CS) has not been yet determined."2.87Therapeutic and pharmaco-biological, dose-ranging multicentre trial to determine the optimal dose of TRAnexamic acid to reduce blood loss in haemorrhagic CESarean delivery (TRACES): study protocol for a randomised, double-blind, placebo-controlled trial. ( Allorge, D; Baptiste, AS; Bouthors, AS; Duhamel, A; Hennart, B; Jeanpierre, E; Lannoy, D; Saidi, I; Simon, E; Susen, S, 2018)
" In order to avoid adverse effects associated with intravenous administration, topical use has been proposed as an alternative."2.87Efficacy and safety of topical tranexamic acid in knee arthroplasty. ( Dauder-Gallego, C; Ferreño-Márquez, D; López-Hualda, Á; Martínez-Martín, J, 2018)
"Tranexamic acid has been shown to be effective for minimizing perioperative blood loss in liposuction."2.87Use of Tranexamic Acid to Reduce Blood Loss in Liposuction. ( Cansancao, AL; Cansancao, B; Condé-Green, A; David, JA; Vidigal, RA, 2018)
"Radical cystectomy for bladder cancer is associated with a high risk of needing red blood cell transfusion."2.87Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial. ( Breau, RH; Bryson, G; Cagiannos, I; Cnossen, S; Fergusson, DA; Kanji, S; Knoll, G; Lavallée, LT; Mallick, R; Momoli, F; Morash, C; Turgeon, A; Witiuk, K; Zarychanski, R, 2018)
"No episodes of deep venous thrombosis or pulmonary embolism occurred in all cases."2.87Multiple-Dose Intravenous Tranexamic Acid Further Reduces Hidden Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial. ( Chen, G; Huang, Q; Huang, Z; Lei, Y; Pei, F; Xie, J, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic agent that has shown promise in reducing blood loss during total hip arthroplasty (THA)."2.87Tranexamic acid use during total hip arthroplasty: A single center retrospective analysis. ( Ackermann, W; Bergese, SD; Ellis, T; Glassman, A; Granger, J; Joseph, N; Mahmoud, AR; Moran, K; Niermeyer, W; Rogers, B; Ryan, J; Salon, N; Stoicea, N, 2018)
"TRAC-24 will help to determine whether an extended TXA dosing regimen can further reduce blood loss following primary THA and TKA."2.87Assessment of the effect of addition of 24 hours of oral tranexamic acid post-operatively to a single intraoperative intravenous dose of tranexamic acid on calculated blood loss following primary hip and knee arthroplasty (TRAC-24): a study protocol for a ( Adams, C; Agus, A; Bell, J; Benson, G; Beverland, D; Bryce, L; Campbell, C; Dorman, A; Eggleton, A; Gardner, E; Hill, J; Hogg, R; Magill, P; Martin, U; McFarland, M; Mockford, B; Molloy, D; Murphy, L; O'Hagan, S; Phair, G, 2018)
"Only one patient in IV group exhibited deep venous thrombosis."2.87Tranexamic acid in primary total knee arthroplasty without tourniquet: a randomized, controlled trial of oral versus intravenous versus topical administration. ( Cao, C; Li, DH; Li, LL; Meng, WK; Pei, FX; Wang, D; Wang, HY; Zeng, WN; Zhou, ZK, 2018)
"To compare the efficacy and safety of intra-articular combined with intravenous administration of tranexamic acid (TXA) with different dosage for reducing blood loss in primary total knee arthroplasty (TKA)."2.87[Comparison of combined intravenous and topical use of tranexamic acid with different dosage in primary total knee arthroplasty]. ( Chen, Y; Deng, J; Li, G; Wu, J; Zhang, C, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss."2.87Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial. ( Brustowicz, RM; Emans, JB; Glotzbecker, MP; Goobie, SM; Hedequist, D; Hresko, MT; Karlin, LI; McCann, ME; Sethna, NF; Zurakowski, D, 2018)
" Secondary outcomes were calculated blood loss, number of units transfused during hospitalization, and incidence of adverse events at 30 and 90 days including thromboembolic event, wound complications, reoperation, hospital readmission, and all-cause mortality."2.84Tranexamic Acid Safely Reduced Blood Loss in Hemi- and Total Hip Arthroplasty for Acute Femoral Neck Fracture: A Randomized Clinical Trial. ( Cross, WW; Houdek, MT; Pagnano, MW; Sems, SA; Watts, CD, 2017)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in total knee arthroplasty (TKA)."2.84Tranexamic Acid in Knee Surgery Study-A Multicentered, Randomized, Controlled Trial. ( Aoina, J; Hill, AG; Munro, JT; Poutawera, V; Stowers, MDJ; Vane, A, 2017)
"No deep venous thrombosis or other severe complications had occurred."2.84Intra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial. ( Wang, J; Wang, Q; Zhang, X, 2017)
"Tranexamic acid is a proven drug used for reduction of intraoperative blood loss in spinal surgery."2.84The effectiveness of low-dose and high-dose tranexamic acid in posterior lumbar interbody fusion: a double-blinded, placebo-controlled randomized study. ( Hey, HWD; Hong, SJ; Juh, HS; Kim, CK; Kim, HJ; Kim, HS; Kim, KT; Kim, YC, 2017)
"The total blood loss and postoperative blood loss were significantly lower in groups B and C without any difference between them."2.84Efficacy of a Single Dose and an Additional Dose of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty. ( Cai, M; Ge, W; Li, S; Sun, Q; Wu, J; Yu, X, 2017)
"v, a maintenance dosage of 2 mg/kg/h TA, or an equivalent volume of normal saline."2.84Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial. ( Jiang, D; Ou, Y; Quan, Z; Shi, H; Zhao, Z; Zhu, Y, 2017)
" combined with topical administration of TXA decreases postoperative blood loss and transfusion rates after THA."2.84Intravenous Combined with Topical Administration of Tranexamic Acid in Primary Total Hip Arthroplasty: A Randomized Controlled Trial. ( Kang, PD; Pei, FX; Shen, B; Si, HB; Yang, J; Zeng, Y; Zhou, ZK, 2017)
"The combined (IV (intravenous) + topical) use of tranexamic acid (TXA) has been shown to be a safe method and more effective than single (IV or topical) application."2.84The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty. ( Akkaya, M; Basaran, SH; Bozkurt, M; Cankaya, D; Dasar, U; Satilmis, AB, 2017)
"Tranexamic acid results in lower bleeding irrespective of the mode of administration compared to control group."2.84A randomized control trial to evaluate the effectiveness of intravenous, intra-articular and topical wash regimes of tranexamic acid in primary total knee arthroplasty. ( Jin, C; Park, YJ; Prakash, J; Seon, JK; Song, EK, 2017)
"Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss and the need for transfusions when administered intravenously in total hip arthroplasty."2.84Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty: A Randomized Controlled Trial. ( Della Valle, CJ; Fillingham, YA; Gerlinger, TL; Kayupov, E; Moric, M; Okroj, K; Plummer, DR, 2017)
" However, in infants less than 1 year of age, the optimal dosing based on pharmacokinetic (PK) considerations is still under discussion."2.84Pharmacokinetics of tranexamic acid in neonates and infants undergoing cardiac surgery. ( Braun, S; Burg, S; Gertler, R; Grassin-Delyle, S; Gruber, M; Martin, K; Tassani-Prell, P; Urien, S; Wiesner, G, 2017)
" Antifibrinolytic drugs are part of a multifaceted approach aimed at reducing bleeding, though sufficiently sized pediatric studies are sparse, and dosing algorithms are heterogeneous."2.82Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac Surgery on Cardiopulmonary Bypass: A Systematic Review and Meta-analysis. ( Hunt, BJ; Murdoch, IA; Sangaran, DP; Siemens, K; Tibby, SM, 2022)
"This meta-analysis provides strong evidence that TXA is a safe and effective agent to reduce perioperative blood loss in hip fracture surgery."2.82Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials. ( Antoniou, G; Masouros, P; Nikolaou, VS, 2022)
" Then, subgroup and meta-regression analyses were conducted to disclose the influence of geographic area, fracture type, administration route, frequency and dosage of TXA, blood transfusion threshold, and follow-up duration on the overall effect."2.82Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice. ( Deng, S; Liang, J; Liu, W, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent associated with reduced blood loss and mortality in a wide range of procedures, including spine surgery, traumatic brain injury, and craniosynostosis."2.82Association of tranexamic acid with decreased blood loss in patients undergoing laminectomy and fusion with posterior instrumentation: a systematic review and meta-analysis. ( Brown, NJ; Chan, A; Choi, EH; Gendreau, JL; Himstead, A; Lien, BV; Oh, MY; Ong, V; Ransom, SC; Sahyouni, R; Shahrestani, S; Tafreshi, AR; Tran, K, 2022)
" Unease regarding possible systemic adverse effects prevents widespread systemic use, but local use of tranexamic acid is gaining popularity among plastic surgeons."2.82Safety and Efficacy of Local Tranexamic Acid for the Prevention of Surgical Bleeding in Soft-Tissue Surgery: A Review of the Literature and Recommendations for Plastic Surgery. ( Ausen, K; Fossmark, R; Pleym, H; Spigset, O, 2022)
"Tranexamic acid has been increasingly used for blood conservation in cardiac surgery."2.82Tranexamic acid reduces postoperative blood loss in Chinese pediatric patients undergoing cardiac surgery: A PRISMA-compliant systematic review and meta-analysis. ( He, LX; Yao, YT; Zou, ZY, 2022)
"Usually, TXA-associated seizures persist for a few minutes with no progression into status epilepticus."2.82Tranexamic acid-associated fatal status epilepticus in a paediatric non-cardiac surgery: A case report and literature review. ( Aboul-Fotouh, S; Habib, MZ; Hassan, BEE; Magdy, SM, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic drug primarily used for reducing blood loss in patients with major bleedings."2.82Tranexamic Acid and Its Potential Anti-Inflammatory Effect: A Systematic Review. ( Hvas, AM; Krog, J; Okholm, SH, 2022)
"Tranexamic acid (TXA) has been widely used for bleeding reduction in spinal surgery."2.82Optimal administration strategies of tranexamic acid to minimize blood loss during spinal surgery: results of a Bayesian network meta-analysis. ( Cao, Z; Guo, J; Li, Q; Li, Y; Wu, J, 2022)
"Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood loss and allogeneic red blood cell transfusion in several clinical settings."2.82Update on Applications and Limitations of Perioperative Tranexamic Acid. ( Butwick, AJ; Goobie, SM; Hare, GMT; Mazer, CD; Patel, PA; Pivalizza, EG; Wyrobek, JA, 2022)
"Tranexamic acid (TXA) has been widely used in various orthopaedic subspecialities to decrease blood loss, transfusions, and wound complications."2.82Tranexamic Acid Utilization in Foot and Ankle Surgery: A Meta-analysis. ( Attia, AK; Blankenhorn, B; El Khatib, S; Hantouly, A; Hsu, R; Salameh, M, 2022)
"TXA can considerably decrease surgical blood loss, postoperative drainage, reduce operative times, hospital stays, and transfusion rates."2.82The Safety and Effectiveness of Tranexamic Acid in Lumbar Interbody Fusion Surgery: An Updated Meta-analysis of Randomized Controlled Trials. ( Chen, CM; Lin, GX; Zheng, L; Zhu, MT, 2022)
"Tranexamic acid (TXA) has been investigated further in patients with hip surgery and shows reduction of bleeding."2.82Patient blood management and patient safety. ( Steinbicker, AU; Zacharowski, K; Zoller, H, 2022)
"Tranexamic acid (TXA) has become a commonly used perioperative intervention in total joint arthroplasty, shoulder and knee arthroscopy, and spinal procedures in order to minimize blood loss, hematoma formation, hemarthrosis, and wound healing complications."2.82Tranexamic Acid in Foot and Ankle Surgery: A Topical Review and Value Analysis. ( Gonzalez, TA; Jackson, B; Johns, WL; Walley, KC, 2022)
"Tranexamic acid is an antifibrinolytic agent that has shown to effectively reduce bleeding complications within other surgical and medical areas."2.82Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy-a double-blinded randomized placebo-controlled trial. ( Bergholt, T; Moeller, C; Ottesen, B; Ravn, P; Schouenborg, L; Settnes, A; Topsoee, MF, 2016)
"Tranexamic acid can be effective at decreasing blood loss and transfusion requirements associated with total hip arthroplasty (THA), but few studies have compared the efficacy of different intravenous dosing regimes."2.82Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses. ( Kang, P; Ma, J; Pei, F; Wang, C; Xie, J; Yue, C, 2016)
"Fixed dose of TXA for patients undergoing simultaneous bilateral TKAs was effective and safe in reducing total blood loss and allogeneic blood transfusion needs without any additional thromboembolic risk."2.82Effectiveness and Safety of Fixed-Dose Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Randomized Double-Blind Controlled Trial. ( Cao, X; Chen, X; Guo, K; Yang, C; Zhu, J; Zhu, Q, 2016)
"No pulmonary embolism was observed and no significant differences were found in other complications between the 2 groups."2.82The Efficacy and Safety of Combination of Intravenous and Topical Tranexamic Acid in Revision Hip Arthroplasty: A Randomized, Controlled Trial. ( Cao, F; Shen, B; Si, HB; Wu, YG; Yang, TM; Zeng, Y, 2016)
"The optimal dosage and timing of tranexamic acid (TXA) in total knee arthroplasty (TKA) are undetermined."2.82Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial. ( Ma, J; Pei, F; Xie, J; Yao, H; Yue, C, 2016)
"Tranexamic acid (TXA) is an antifibrinolytic agent that decreases bleeding in various settings, but has not been well studied in patients undergoing liver resection."2.82Major liver resection, systemic fibrinolytic activity, and the impact of tranexamic acid. ( Coburn, NG; Hallet, J; Karanicolas, PJ; Law, CH; Lin, Y; McCluskey, SA; Nascimento, B; Pawliszyn, J; Tarshis, J, 2016)
"No deep vein thrombosis was detected through Doppler ultrasound examination."2.80The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trial. ( Ding, PJ; Li, J; Lv, YM; Yang, Y; Ying-Ze, Z, 2015)
"Tranexamic Acid (TXA) has been used in cardiac and orthopedic surgeries, including major spinal surgeries, to reduce blood loss and transfusion requirements for decades."2.80Preliminary investigation of high-dose tranexamic acid for controlling intraoperative blood loss in patients undergoing spine correction surgery. ( Lenke, LG; Li, T; Si, Y; Wang, Y; Xiao, J; Xie, J; Zhang, Y; Zhao, Z, 2015)
"TXA treatment without drainage during TKA reduces the amount of blood transfusions required without increasing the rate of adverse events."2.80Safety and efficacy of intra-articular tranexamic acid injection without drainage on blood loss in total knee arthroplasty: A randomized clinical trial. ( Cao, JG; Li, ZJ; Liu, J; Sun, ZH; Wang, CG, 2015)
"Tranexamic acid (TXA) is an antifibrinolytic agent that has been shown to significantly reduce blood loss and transfusion requirements after total knee and hip arthroplasty."2.80Neer Award 2015: A randomized, prospective evaluation on the effectiveness of tranexamic acid in reducing blood loss after total shoulder arthroplasty. ( Gillespie, R; Gobezie, R; Joseph, S; Shishani, Y; Streit, JJ, 2015)
"Tranexamic acid is an antifibrinolytic agent which blocks plasmin-mediated fibrin degradation."2.80[The Effect of Tranexamic Acid on Blood Loss after Primary Unilateral Total Knee Arthroplasty. Prospective Single-Centre Study]. ( Mezera, V; Musil, D; Pertlíček, J; Sadovský, P; Stehlík, J, 2015)
"Tranexamic acid resulted in a lower mean maximum decline in postoperative hemoglobin levels when compared to placebo (P = 0."2.79Topical administration of tranexamic acid in primary total hip and total knee arthroplasty. ( Cassatt, KB; Garton, AS; Kincaid-Cinnamon, KA; Lemke, JH; Martin, JG; Westendorf, DS, 2014)
" However, dosing based on pharmacokinetic data to optimally inhibit fibrinolysis is unknown."2.79Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: a randomised, controlled study. ( Barvais, L; Cacheux, C; Faraoni, D; Ickx, BE; Levy, JH; Van Aelbrouck, C, 2014)
"Tranexamic acid is an antifibrinolytic drug used widely to prevent bleeding."2.79Comparison between intravenous and intra-articular regimens of tranexamic acid in reducing blood loss during total knee arthroplasty. ( Bhatty, S; Gulati, A; Paul, R; Rajoli, SR; Saini, R; Soni, A, 2014)
"234."2.78Effect of tranexamic acid on reducing postoperative blood loss in combined hypotensive epidural anesthesia and general anesthesia for total hip replacement. ( Cho, CH; Kim, JS; Lee, YC; Park, SJ, 2013)
"Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that has been successfully used intravenously to stop bleeding after total knee replacement."2.78Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K). ( Alshryda, S; Anand, S; Hungin, AP; Logishetty, R; Maheswaran, S; Mason, J; Nargol, A; Sarda, P; Stothart, B; Tulloch, C; Vaghela, M, 2013)
"Tranexamic acid is a synthetic antifibrinolytic agent that has been successfully used intravenously to control bleeding after total hip replacement."2.78Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H). ( Ahmad, H; Alshryda, S; Cooke, N; Hungin, AP; Logishetty, R; Mason, J; McPartlin, L; Nargol, A; Sarda, P; Tang, S; Vaghela, M, 2013)
"Ecallantide is a recombinant peptide in the same class as aprotinin that inhibits plasma kallikrein, a major component of the contact coagulation and inflammatory cascades."2.77A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial). ( Bokesch, PM; Grocott, HP; Levy, JH; Mazer, CD; Smith, PK; Szabo, G; Vetticaden, S; Wheeler, A; Wojdyga, R, 2012)
" In this study, we investigated the efficacy of temporary clamping of the drain either or not in combination with tranexamic acid administration for controlling blood loss after TKA."2.77Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial. ( Chareancholvanich, K; Narkbunnam, R; Pornrattanamaneewong, C; Siriwattanasakul, P, 2012)
"Forty consecutive patients with cervical compressive myelopathy were prospectively randomized into groups that received 15 mg/kg body weight of TXA or placebo intravenously before the skin incision was made."2.76Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study. ( Misawa, H; Ohta, H; Shimogata, M; Tsutsumimoto, T; Yoda, I; Yui, M, 2011)
"Surgical correction of craniosynostosis in children is associated with substantial intraoperative bleeding."2.76Intraoperative tranexamic acid reduces blood transfusion in children undergoing craniosynostosis surgery: a randomized double-blind study. ( Bigorre, M; Bringuier, S; Canaud, N; Capdevila, X; Dadure, C; Raux, O; Rochette, A; Sauter, M, 2011)
"No patient in either group developed deep vein thrombosis or pulmonary embolism up to 3 months."2.75Effects of tranexamic acid on blood loss during total hip arthroplasty. ( Ballal, MS; Denn, PG; Mitchell, P; Singh, J, 2010)
"Tranexamic acid has been used to reduce blood loss and the subsequent need for transfusion in orthopedic, spinal, and cardiac surgery."2.74The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial. ( Choi, WS; Irwin, MG; Samman, N, 2009)
"Tranexamic acid is a fibrinolytic inhibitor which reduces blood loss in total knee replacement."2.74The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement. ( Ahmad, M; Biant, LC; Field, RE; Rajesparan, K, 2009)
"Tranexamic acid does not seem to be a useful adjunct in myomectomy if given according to the described protocol in this study."2.73Intravenous tranexamic acid use in myomectomy: a prospective randomized double-blind placebo controlled study. ( Caglar, GS; Haberal, A; Kayikcioglu, F; Tasci, Y, 2008)
"Tranexamic acid was used to reduce postoperative drainage and allogenic blood transfusion requirements in patients undergoing on-pump primary coronary bypass surgery."2.73Tranexamic acid and primary coronary artery bypass surgery: a prospective study. ( Maddali, MM; Rajakumar, MC, 2007)
" In Group A, 1 g of tranexamic acid dissolved in 250 ml of normal saline was intravenously infused before deflation of the tourniquet; another intravenous administration of the same drug of the same dosage was given 3 hours later."2.73[Clinical comparative studies on effect of tranexamic acid on blood loss associated with total knee arthroplasty]. ( Gao, Z; Yu, J; Zhang, F, 2007)
"Tranexamic acid (TXA) combined with rivaroxaban (RA) has been widely used in total knee replacement (TKA)."2.72Efficacy and Safety of Tranexamic Acid Combined with Rivaroxaban in Primary Total Knee Arthroplasty: A Meta-Analysis of Randomized Controlled Trials. ( Du, C; Liu, Z; Ma, J; Meng, B; Zhang, G, 2021)
"Tranexamic acid (TXA) is an effective and commonly used hemostatic agent for perioperative blood loss in various surgical specialties."2.72Advances in surgical hemostasis: a comprehensive review and meta-analysis on topical tranexamic acid in spinal deformity surgery. ( Barra, ME; Fatima, N; Hadzipasic, M; Massaad, E; Roberts, RJ; Shankar, GM; Shin, JH, 2021)
"The primary outcome was surgical blood loss."2.72A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss: A Meta-analysis. ( Heyns, M; Knight, P; Steve, AK; Yeung, JK, 2021)
"Tranexamic acid (TXA) was conducive in total knee arthroplasty (TKA) to reduce blood loss and transfusion demand."2.72What is the ideal route of administration of tranexamic acid in total knee arthroplasty? A meta-analysis based on randomized controlled trials. ( Guo, W; Lu, F; Sun, X; Wang, W; Zhang, Q, 2021)
"Tranexamic acid (TXA) use has expanded across many surgical specialties."2.72The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries. ( Adams, JD; Marshall, WA, 2021)
" No adverse drug reactions or in-hospital deaths were reported."2.72Safety and efficacy of tranexamic acid in minimizing perioperative bleeding in extrahepatic abdominal surgery: meta-analysis. ( Adiamah, A; Gomez, D; Koh, A; Sanyal, S, 2021)
" Few studies found adverse events, and no difference in incidence or type of adverse events was seen between the antifibrinolytic and the placebo group."2.72Efficacy and Safety of Antifibrinolytic Drugs in Pediatric Surgery: A Systematic Review. ( Fenger-Eriksen, C; Hansen, AK; Hovgesen, NT; Hvas, AM; Larsen, JB, 2021)
"Tranexamic acid (TXA) is a kind of antifibrinolytic agent that has been widely used in spinal surgery."2.72The Efficacy and Safety of Topical Tranexamic Acid for Spinal Surgery. ( Feng, H; Guo, T; Ma, X; Wang, J; Xuan, W, 2021)
"Treatment with tranexamic acid was not associated with a higher incidence of myocardial ischemia or other thrombotic events."2.71Tranexamic acid reduces bleeding after off-pump coronary artery bypass grafting. ( Brucek, P; Jares, M; Straka, Z; Vanek, T, 2003)
"Tranexamic acid (TA) has less side-effects, but data regarding its efficacy are controversial."2.71Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial. ( Geissler, HJ; Hekmat, K; Kampe, S; Kasper, SM; Mehlhorn, U; Weber, HJ; Zimmermann, T, 2004)
"The volume of postoperative blood loss was recorded at two-hour intervals for the first twelve hours and then again at twenty-four hours, and the values were compared between the two groups."2.71Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty. ( Fuji, T; Masuhara, K; Yamasaki, S, 2005)
"Tranexamic acid appears to be an effective and economic drug for reduction of blood loss in cemented primary hip arthroplasty for osteoarthritis."2.71Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis. ( Korkala, OL; Niskanen, RO, 2005)
"Tranexamic acid 10 mg kg-1 was given at conclusion of surgery and again 3 h later."2.70Tranexamic acid given intraoperatively reduces blood loss after total knee replacement: a randomized, controlled study. ( Juelsgaard, P; Madsen, F; Sørensen, JV; Veien, M, 2002)
"Case material included 25 patients with hemophilia (9 children and 16 adults) with high-responding inhibitors and 3 patients with acquired factor VIII inhibitors."2.70Relationship between factor VII activity and clinical efficacy of recombinant factor VIIa given by continuous infusion to patients with factor VIII inhibitors. ( Baudo, F; Gringeri, A; Morfini, M; Rocino, A; Santagostino, E; Scaraggi, FA, 2001)
"Tranexamic acid was as effective and as safe as high dose aprotinin."2.68[Fibrinolytic inhibitors and prevention of bleeding in cardiac valve surgery. Comparison of tranexamic acid and high dose aprotinin]. ( Benmosbah, L; Boughenou, F; Carpentier, A; Cousin, MT; Madi-Jebara, S; Massonnet-Castel, S, 1995)
" This study explored the dose-response relationship of tranexamic acid for hemostatic efficacy after cardiac operation."2.68The dose-response relationship of tranexamic acid. ( Grunewald, KE; Horrow, JC; Parmet, JL; Strong, MD; Van Riper, DF, 1995)
" (3) The appropriate, empirically established, dosage and administration patterns of TEA for CDH repair during ECMO seem to be one bolus of 4 mg/kg TEA intravenously 30 minutes before the anticipated CDH repair and a continuous infusion of 1 mg/kg/h TEA during the 24 hours after CDH repair."2.68Surgical repair of congenital diaphragmatic hernia during extracorporeal membrane oxygenation: hemorrhagic complications and the effect of tranexamic acid. ( de Haan, AF; Festen, C; Geven, WB; van der Staak, FH, 1997)
"When tranexamic acid was administered immediately after the operation, it had a minor beneficial effect."2.68Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: a double-blind, randomized, placebo-controlled trial. ( Brown, RS; Mongan, PD; Thwaites, BK, 1997)
"The tranexamic acid dose was 10 mg infused in 500 mL of normal saline."2.68Beneficial effect of both tranexamic acid and aprotinin on blood loss reduction in reoperative valve replacement surgery. ( Ansley, DM; Dryden, PJ; Jamieson, WR; Merrick, PM; O'Connor, JP; Sadeghi, H, 1997)
"Tranexamic acid was an effective drug in bleeding control and in reducing blood transfusion in the postoperative of patients submitted to myocardial revascularization."2.67[Use of tranexamic acid for bleeding control in myocardial revascularization]. ( Cordeiro, CO; Couto, WJ; Freitas, M; Gregori Júnior, F; Ketzer, JL; Rosa, V; Silva, L; Silva, SS; Wanderley, WR, 1994)
" Tranexamic acid dosing regimens should be decreased in patients with chronic kidney dysfunction secondary to reduced clearance and drug accumulation."2.66Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures. ( Choi, S; Jerath, A; Karanicolas, P; Pang, KS; Taam, J; Wasowicz, M; Yang, QJ, 2020)
"Tranexamic acid (TXA) has been demonstrated to reduce blood loss following primary total knee and hip arthroplasty."2.66Comparison of efficacy and safety between oral and intravenous administration of tranexamic acid for primary total knee/hip replacement: a meta-analysis of randomized controlled trial. ( Fei, Y; Gao, X; Li, XL; Liu, WF; Liu, Y; Ye, W, 2020)
"Tranexamic acid is a safe and effective treatment modality, and consideration should be given to use multiple doses and combine different modes of administration."2.66Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2). ( Mastel, MS; van der Merwe, JM, 2020)
"Tranexamic acid (TXA) is an anti-fibrinolytic agent that acts by inhibiting plasminogen activation and fibrinolysis."2.66The never ending success story of tranexamic acid in acquired bleeding. ( Franchini, M; Mannucci, PM, 2020)
"Tranexamic acid (TXA) is a widely used antifibrinolytic agent worldwide and whether TXA influences ACT value in cardiac surgical patients remains unknown."2.66The effect of tranexamic acid on the values of activated clotting time in patients undergoing cardiac surgery: A PRISMA-compliant systematic review and meta-analysis. ( He, LX; Tan, JC; Yao, YT, 2020)
"Oral tranexamic acid (TXA) has been demonstrated to reduce the blood loss in primary total knee and hip arthroplasty, but the optimal regimen of oral TXA administration is still unknown."2.66The optimal regimen of oral tranexamic acid administration for primary total knee/hip replacement: a meta-analysis and narrative review of a randomized controlled trial. ( Li, XL; Liu, WF; Liu, Y; Shao, J; Ye, W, 2020)
"The optimal dosage and administration approach of tranexamic acid (TXA) in primary total knee arthroplasty (TKA) remains controversial."2.66Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty. ( Hong, P; Li, J; Liu, R; Rai, S; Tang, X; Ze, R, 2020)
" The results of subgroup analysis revealed that hemostatic techniques, which could substantially decrease the rate of ABT, were cell salvage with the transfusion trigger of 9 mg/dl, fibrin sealant with a dosage of 10 ml, and postoperative flexion position."2.61Hemostatic techniques to reduce blood transfusion after primary TKA: a meta-analysis and systematic review. ( Dong, Z; Han, L; Qi, J; Song, Y; Wang, F, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic drug, which has demonstrated a significant reduction in perioperative blood loss in many pediatric surgical procedures such as cardiac surgery and scoliosis surgery."2.61Reducing blood loss in pediatric craniosynostosis surgery by use of tranexamic acid. ( Eustache, G; Riffaud, L, 2019)
" For prophylactic perioperative administration, different dosage regimens exist for adults."2.61[Prophylactic use of tranexamic acid in noncardiac surgery : Update 2017]. ( Schefold, JC; Stueber, F; Waskowski, J, 2019)
" Furthermore, it is safe and does not increase the risk of thrombotic events."2.61The Efficacy and Safety of Intravenous Tranexamic Acid in Reducing Surgical Blood Loss in Posterior Lumbar Interbody Fusion for the Adult: A Systematic Review and a Meta-Analysis. ( Chen, L; Chen, R; Gong, M; Liu, G; Xiang, Z, 2019)
"The surgical removal of fibroids can be associated with excessive blood loss requiring transfusion."2.61The Effectiveness of Tranexamic Acid at Reducing Blood Loss and Transfusion Requirement for Women Undergoing Myomectomy: A Systematic Review and Meta-analysis. ( Boutet, M; Chen, I; Fergusson, D; Fusca, L; Perelman, I, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic which has been shown to decrease such a burden in particular surgeries."2.61Tranexamic Acid Decreases Blood Transfusion Burden in Open Craniosynostosis Surgery Without Operative Compromise. ( Daniels, DJ; Goyal, A; Lu, VM, 2019)
"Tranexamic acid (TXA) is an inexpensive therapy effective at minimizing perioperative blood loss and transfusion."2.61Exclusion criteria and adverse events in perioperative trials of tranexamic acid: a systematic review and meta-analysis. ( Khair, S; Lampron, J; Perelman, I; Saidenberg, E; Taylor, J; Tinmouth, A; Yates, J, 2019)
" Recent data on TXA's use in spine surgery suggest that TXA remains both efficacious and safe, although the ideal dosing and timing of administration is still a point of disagreement."2.61The Use of Tranexamic Acid to Reduce Surgical Blood Loss: A Review Basic Science, Subspecialty Studies, and The Evolution of Use in Spine Deformity Surgery. ( Kark, J; Slattery, C; Verma, K; Wagner, T, 2019)
"Tranexamic acid has a limited effect on reducing operative time (p < 0."2.61Comprehensive assessment of tranexamic acid during orthognathic surgery: A systematic review and meta-analysis of randomized, controlled trials. ( Liu, S; Ma, C; Wu, Z; Zhao, H, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic agent that reduces bleeding and transfusion in a broad number of adult and pediatric surgeries, as well as in trauma and obstetrics."2.61Tranexamic acid and perioperative bleeding in children: what do we still need to know? ( Faraoni, D; Goobie, SM, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic, and it was used to reduce the perioperative bleeding."2.61Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. ( Li, F; Lu, HS; Ping, WD; Sun, HF; Zhao, QM, 2019)
"Tranexamic acid is an effective treatment to reduce the volume of bleeding during menstruation."2.61Applications of Tranexamic acid in benign gynecology. ( Ingraham, CF; Klebanoff, JS; Marfori, CQ; Moawad, GN; Wu, CZ, 2019)
"Secondary outcomes were length of stay, deep venous thrombosis (DVT) and/or pulmonary embolism (PE)."2.61Transfusions and cost-benefit of oral versus intravenous tranexamic acid in primary total hip arthroplasty: A meta-analysis of randomized controlled trials. ( Chen, H; Ji, M; Liu, W; Tang, J; Wang, N; Xiong, X; Xu, L; Yang, T; Yang, Y, 2019)
" Nevertheless, TXA remains underutilized because of concerns regarding development of adverse events."2.61Exclusion criteria and adverse events in perioperative trials of tranexamic acid in cardiac surgery: a systematic review and meta-analysis. ( Khair, S; Lampron, J; Perelman, I; Saidenberg, E; Taylor, J; Tinmouth, A; Yates, J, 2019)
"Tranexamic acid (TXA) has been used to treat peripartum hemorrhage, while preoperative use of TXA in cesarean section (CS) remains controversial."2.61Prophylactic use of tranexamic acid reduces blood loss and transfusion requirements in patients undergoing cesarean section: A meta-analysis. ( He, L; Liu, S; Wang, Y, 2019)
"Tranexamic acid (TXA) is an antifibrinolytic medication that can reduce perioperative blood loss in TKA."2.58Intra-articular Tranexamic Acid in Primary Total Knee Arthroplasty: Meta-analysis. ( Capps, SG; Moskal, JT, 2018)
"Tranexamic acid (TXA) has been shown to be effective in patients with total knee arthroplasty (TKA) in clinical studies with no consensus with regard to the most appropriate route of administration."2.58Tranexamic Acid in Total Knee Arthroplasty: Mixed Treatment Comparisons and Recursive Cumulative Meta-Analysis of Randomized, Controlled Trials and Cohort Studies. ( Sivaramakrishnan, G; Sridharan, K, 2018)
"Tranexamic acid is an antifibrinolytic agent that has been widely used in other surgical specialties, especially in cardiac, orthopedic, and trauma surgery."2.58The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations. ( Cho, MJ; Rohrich, RJ, 2018)
" Other severe drug-related adverse events occurred very rarely (0."2.58Safety of intravenous tranexamic acid in patients undergoing majororthopaedic surgery: a meta-analysis of randomised controlled trials. ( Franchini, M; Liumbruno, GM; Mannucci, PM; Marano, G; Marietta, M; Mengoli, C; Pupella, S; Vaglio, S, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic drug widely used as a blood-sparing technique in total knee arthroplasty (TKA), and it is usually administrated by intravenous or intraarticular injection."2.58Efficacy and safety of oral tranexamic acid in total knee arthroplasty: A systematic review and meta-analysis. ( Cheng, L; Gao, F; Guo, P; Guo, W; He, Z; Li, Z; Sun, W; Wang, Y, 2018)
"Prostate cancer and benign prostatic hyperplasia have an increased incidence with aging."2.58Systematic review and meta-analyses of tranexamic acid use for bleeding reduction in prostate surgery. ( Cavalheiro, BT; de Oliveira Filho, GR; Longo, MA, 2018)
" IV TXA dosing varied, as 14 (39%) of the studies used a weight-based approach while 22 (61%) used a standard dose."2.58Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty: A Meta-Analysis. ( Gianakos, AL; Haring, RS; Hurley, ET; Liporace, FA; Yoon, RS, 2018)
" Use of repeat IV and oral TXA dosing and higher doses of IV and topical TXA did not significantly reduce blood loss or risk of transfusion."2.58The Efficacy of Tranexamic Acid in Total Knee Arthroplasty: A Network Meta-Analysis. ( Bini, SA; Clarke, HD; Della Valle, CJ; Fillingham, YA; Jevsevar, DS; Johnson, RL; Memtsoudis, SG; Mullen, K; Ramkumar, DB; Sah, AP; Sayeed, SA; Schemitsch, E; Shores, P; Yates, AJ, 2018)
"Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to reduce blood loss in total hip arthroplasty (THA)."2.58The Efficacy of Tranexamic Acid in Total Hip Arthroplasty: A Network Meta-analysis. ( Bini, SA; Clarke, HD; Della Valle, CJ; Fillingham, YA; Jevsevar, DS; Johnson, RL; Memtsoudis, SG; Mullen, K; Ramkumar, DB; Sah, AP; Sayeed, SA; Schemitsch, E; Shores, P; Yates, AJ, 2018)
"Tranexamic acid has an important ability to decrease intraoperative blood loss and hospitalization for lumbar spinal fusion surgery."2.58The Efficacy of Tranexamic Acid on Blood Loss from Lumbar Spinal Fusion Surgery: A Meta-Analysis of Randomized Controlled Trials. ( Du, Y; Feng, C, 2018)
"Tranexamic acid (TXA) has been widely used to decrease transfusion rate in joint replacement surgery."2.58A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery. ( Bai, J; Chen, P; He, J; Liang, Y; Wang, J; Zhang, P, 2018)
"Tranexamic acid (TXA) has been demonstrated to minimize blood loss after total hip arthroplasty."2.58Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis. ( Ha, YC; Kim, TY; Ko, YS; Koo, KH; Lee, YK; Yoon, BH, 2018)
"Tranexamic acid (TXA) is an anti-fibrinolytic agent successfully preventing blood loss when using intravenously (IV) in total hip arthroplasty (THA) and total knee arthroplasty (TKA)."2.58Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta-analysis. ( Gong, G; Han, N; Han, X; Liu, M, 2018)
"A total of 59 participants with haemophilia undergoing dental extraction were involved."2.55Preventing perioperative bleeding in patients with inherited bleeding disorders. ( Beacher, N; Watterson, C, 2017)
" Secondary outcomes were other adverse events, blood transfusion, and blood loss."2.55The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. ( Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C, 2017)
"Tranexamic acid (TXA) has been proven to be effective in reducing blood loss and transfusion rate after total knee arthroplasty (TKA) without increasing the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE)."2.55Is combined use of intravenous and intraarticular tranexamic acid superior to intravenous or intraarticular tranexamic acid alone in total knee arthroplasty? A meta-analysis of randomized controlled trials. ( Liu, G; Liu, J; Liu, Y; Lv, H; Mi, B; Wu, Q; Zha, K, 2017)
"Tranexamic acid (TXA) has been widely used to decrease blood loss and transfusion rates in joint replacement surgery."2.55Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2017)
"20), or incidence of adverse effects such as deep venous thrombosis (odds ratio 1."2.55Efficiency and safety of tranexamic acid in reducing blood loss in total shoulder arthroplasty: A systematic review and meta-analysis. ( Du, GY; He, SW; Mi, LD; Sun, CX; Sun, XG; Zhang, L, 2017)
" In addition, no adverse effect was identified in treatment groups."2.55The efficiency and safety of tranexamic acid for reducing blood loss in open myomectomy: A meta-analysis of randomized controlled trials. ( Lin, X; Wang, D; Wang, L; Wang, Y, 2017)
"Treatment with tranexamic acid (TXA) by intravenous application has been discussed extensively."2.55Comparison of oral versus intravenous application of tranexamic acid in total knee and hip arthroplasty: A systematic review and meta-analysis. ( Kuang, MJ; Lu, B; Ma, JX; Ma, XL; Sun, L; Wang, Y; Zhang, LK; Zhao, J, 2017)
" Further research is necessary to evaluate the efficacy of TXA in revision shoulder arthroplasty and to identify the optimal dosing and route of administration of TXA in shoulder arthroplasty."2.55Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis. ( Bedi, A; Bhandari, M; Horner, N; Khan, M; Kirsch, JM; Koueiter, DM; Miller, BS; Pauzenberger, L; Wiater, JM, 2017)
"In patients with orthopaedic trauma, TXA reduces the risk of blood transfusion, reduces perioperative blood loss, and has no significant effect on the risk of symptomatic thromboembolic events."2.55Tranexamic Acid in Orthopaedic Trauma Surgery: A Meta-Analysis. ( Boone, MD; Gausden, EB; Lorich, DG; OʼGara, B; Qudsi, R; Ruzbarsky, JJ, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to be effective in reducing blood loss and the need for transfusions after several orthopaedic surgeries."2.55Efficacy and Safety of Tranexamic Acid in Orthopaedic Fracture Surgery: A Meta-Analysis and Systematic Literature Review. ( Amer, K; Amer, KM; Haydel, C; Rehman, S, 2017)
"Tranexamic acid (TA) is a potent drug to reduce surgical blood loss in surgery, therefore, as a potential drug for application in THA."2.55Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials. ( Hu, Y; Lei, P; Su, W; Zeng, M; Zhu, J; Zhu, Y, 2017)
"Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent commonly used for the prevention and treatment of bleeding disorders."2.55Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: A report of four cases and review of literature. ( Chow, KM; Kwan, BC; Leung, CB; Li, PK; Ma, TK; Szeto, CC, 2017)
"Tranexamic acid (TXA) is an antifibrinolytic drug used widely to prevent bleeding in total knee arthroplasty (TKA)."2.55Topical versus intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials. ( An, Y; Gao, X; Wang, S, 2017)
"Ovarian cancer is the third most common gynaecological cancer worldwide, with an age-standardised incidence rate of 6."2.53Effectiveness of tranexamic acid in reducing blood loss during cytoreductive surgery for advanced ovarian cancer. ( Kietpeerakool, C; Laopaiboon, M; Lumbiganon, P; Supoken, A, 2016)
"81) or and incidence of adverse effects such as infection (P = 0."2.53Efficiency and Safety of Intravenous Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Systematic Review and Meta-analysis. ( Jiang, X; Ma, JX; Ma, XL, 2016)
"Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty."2.53Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis. ( Chen, P; Fang, Y; He, J; Liang, Y; Wang, J; Zhang, P, 2016)
" The dose and timing to administration TXA is different, and more randomized controlled trials are warranted to clarify the optimal dosing and time to administration TXA."2.53Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty: A meta-analysis. ( Jiang, XQ; Jie, L; Li, HB; Lin, C; Ma, L; Qi, Y; Qin, L; Zhang, ZH; Zhao, XC, 2016)
" No significant difference in deep vein thrombosis (DVT), pulmonary embolism, or other adverse events among the study groups."2.52Is tranexamic acid clinically effective and safe to prevent blood loss in total knee arthroplasty? A meta-analysis of 34 randomized controlled trials. ( Liu, SL; Meng, T; Wang, P; Wu, Q; Zhang, HA; Zhou, X, 2015)
"Tranexamic acid (TXA) is an antifibrinolytic drug used to reduce bleeding in mortality risk situations such as trauma."2.52Efficiency of tranexamic acid in perioperative blood loss in hip arthroplasty: a systematic literature review and meta-analysis. ( Díaz Quijano, DM; Pinzón-Florez, CE; Vélez Cañas, KM, 2015)
"In people with haemophilia or other congenital bleeding disorders undergoing surgical interventions, haemostatic treatment is needed in order to correct the underlying coagulation abnormalities and minimise the bleeding risk."2.52Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery. ( Coppola, A; Di Minno, MN; Tufano, A; Windyga, J; Yeung, C, 2015)
"Uncontrolled bleeding is an important cause of death in trauma victims."2.52Antifibrinolytic drugs for acute traumatic injury. ( Coats, TJ; Ker, K; Roberts, I; Shakur, H, 2015)
" The question addressed was: what dose of tranexamic acid is most effective and safe for adult patients undergoing cardiac surgery? Altogether 586 papers were found using the reported search, of which 12 represented the best evidence to answer the clinical question."2.52What dose of tranexamic acid is most effective and safe for adult patients undergoing cardiac surgery? ( Dearman, C; Hodgson, S; Larvin, JT, 2015)
" To further investigate the safe and effective role of using tranexamic acid (TA) in reducing transfusion rate and blood loss in total knee arthroplasty."2.52Safety and Efficacy of Tranexamic Acid in Total Knee Arthroplasty. ( Li, W; Liu, J; Qiu, Y; Xu, P; Yu, X; Zhu, Y, 2015)
" Both topical and intravenous administration of TXA, in a variety of dosing regimens, has proven effective."2.52Tranexamic Acid in Hip and Knee Arthroplasty. ( Melvin, JS; Sierra, RJ; Stryker, LS, 2015)
"Fibrin sealant also has this potential, but is not more potent than tranexamic acid."2.52Prevention of post-operative anaemia in hip and knee arthroplasty--a systematic review. ( Husted, H; Khan, N; Troelsen, A, 2015)
"The present meta-analysis indicated that intra-articular injection of TXA in patients undergoing TKA may reduce total blood loss and the need for blood transfusions, particularly when a high dosage of TXA is used (≥30 mg/ml), without any increase in the risk of post-operative DVT."2.50Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature. ( Wei, C; Yan, G; Ying-Ze, Z; Yuejv, L; Zhao-Yu, C, 2014)
"Tranexamic acid was intra-articularly injected in total knee arthroplasty (TKA) to reduce blood loss and transfusion."2.50Safety and efficacy of intra-articular injection of tranexamic acid in total knee arthroplasty. ( Fu, X; Li, YM; Li, ZJ; Liu, WX; Ma, XL; Zhang, Y, 2014)
"Tranexamic acid has been shown to reduce the need for a blood transfusion in adult patients undergoing elective surgery but its effects in patients undergoing emergency or urgent surgery is unclear."2.49Tranexamic acid for reducing mortality in emergency and urgent surgery. ( Ker, K; Morales Uribe, CH; Perel, P; Roberts, I, 2013)
"Meanwhile TA is recommended to reduce deep vein thrombosis and pulmonary embolism following TKA."2.49Use of intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials. ( Chen, C; Fu, DJ; Guo, L; Yang, L, 2013)
"To evaluate the effectiveness and safety of tranexamic acid (TEA) treatment in reducing perioperative blood loss and transfusion for patients receiving primary unilateral total knee arthroplasty (TKA) and to explore the most effective and safe protocol."2.49A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty. ( Chen, C; Chen, H; Huang, W; Liu, Q; Tan, J, 2013)
"Tranexamic acid (TXA) is an antifibrinolytic drug used as a blood-sparing technique in many surgical specialties."2.49Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis. ( Evans, HM; Gandhi, R; Mahomed, NN; Mahomed, SR, 2013)
" It reduces total blood loss and the need for blood transfusion, particularly in the using of high dosage of TXA (≥ 15 mg/kg), yet does not increase the risk of postoperative DVT."2.49Is tranexamic acid effective and safe in spinal surgery? A meta-analysis of randomized controlled trials. ( Fu, X; Li, ZJ; Ma, XL; Xing, D; Zang, JC; Zhang, HF, 2013)
" Although TXA is a long known drug available on the market for more than 50 years, the studies connecting factors of indication, dosage regimen and safety are limited especially in children and infants."2.49[Hemostasis and antifibrinolytic therapy in major pediatric surgery]. ( Hertfelder, HJ; Schindler, E, 2013)
"Tranexamic acid is a safe drug to treat hyperfibrinolysis during prostate resection."2.49[Current strategies to minimize of blood loss during radical prostatectomy]. ( Hachenberg, T; Strang, CM, 2013)
"Surgical correction of craniosynostosis in children is associated with substantial intraoperative bleeding."2.49Tranexamic Acid reducing blood transfusion in children undergoing craniosynostosis surgery. ( Feng, G; Hu, J; Li, J; Li, Y; Luo, E; Song, G; Yang, P; Zhu, S, 2013)
" There was marked variability in the dosage and infusion schemes used in different studies."2.48Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis. ( De Hert, S; Faraoni, D; Melot, C; Van der Linden, P; Willems, A, 2012)
"The meta-analysis shows that the use of tranexamic acid for patients undergoing total knee arthroplasty is effective and safe for the reduction of blood loss."2.48Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis. ( Chen, WP; Wu, LD; Yang, ZG, 2012)
"Uncontrolled bleeding is an important cause of death in trauma victims."2.47Antifibrinolytic drugs for acute traumatic injury. ( Coats, T; Ker, K; Roberts, I; Shakur, H, 2011)
" A total of 19 trials were eligible: 18 used intravenous administration, one also evaluated oral dosing and one trial evaluated topical use."2.47Tranexamic acid in total knee replacement: a systematic review and meta-analysis. ( Alshryda, S; Blenkinsopp, J; Mason, JM; Nargol, A; Sarda, P; Sukeik, M, 2011)
"Tranexamic acid and aprotinin have been shown to reduce blood loss and transfusions in clinical trials with variable results."2.43The use of antifibrinolytic agents in total hip arthroplasty: a meta-analysis. ( Gill, JB; Rosenstein, A, 2006)
"Tranexamic acid does not increase the risk of thromboembolic complications such as deep vein thrombosis, pulmonary embolism, thrombotic cerebral vascular accident, or myocardial infarction (OR 0."2.42Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis. ( Ho, KM; Ismail, H, 2003)
"Tranexamic acid was usually added for mucosal surgery."2.41Retrospective review of the management of elective surgery with desmopressin and clotting factor concentrates in patients with von Willebrand disease. ( Griffioen, A; Harrington, C; Lee, CA; Nitu-Whalley, IC, 2001)
"We failed to observe a difference in infection risk after adjustment for confounders and surgeon differences (hazard ratio [HR] 1."1.91Tranexamic acid is not associated with decreased infection risk after primary shoulder arthroplasty: a cohort study of 9276 patients. ( Chan, PH; Gorbaty, J; McElvany, MD; Prentice, HA; Yian, EH, 2023)
"Tranexamic acid is an effective treatment to reduce blood loss."1.91The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan. ( Chen, JW; Hou, SM; Hsu, HW; Hsu, LI; Wei, ST, 2023)
" Further studies are needed to adjust dosage of EACA to make better comparison of the two drugs."1.91Combination of Intravenous and Intra-Articular Application of Tranexamic Acid and Epsilon-Aminocaproic Acid in Primary Total Knee Arthroplasty: A Prospective Randomized Controlled Trial. ( Li, M; Liu, Y; Ma, J; Shen, B; Si, H; Xu, J; Zheng, C, 2023)
"Surgical resection of posterior fossa tumors (PFT) in the pediatric age group often results in significant intraoperative blood loss."1.91Effect of administration of tranexamic acid on blood loss and transfusion requirements in children undergoing posterior fossa tumor excision: a retrospective cohort study. ( George, SE; Moorthy, RK; Singh, G; Thakkar, K; Yadav, B, 2023)
" Although the use of TXA for multilevel spine surgery is increasing, there remains widespread equivocality regarding ideal dosing regimens."1.91The Administration of Tranexamic Acid For Complex Spine Surgery. ( Cosgrove, MS; Jockel, K; Lee, A; Reilly, D; Wijesekera, S, 2023)
"Bleeding complications are not uncommon after breast reduction surgery, and recently, tranexamic acid (TXA) as an antifibrinolytic agent has been used in various surgical specialties as a way to minimizes such adverse outcomes."1.91The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates. ( Kebede, S; Losken, A; Marxen, T; Om, A, 2023)
"The aim of the study was to evaluate the efficacy of aggressive warming combined with tranexamic acid (TXA) during total hip arthroplasty (THA)."1.91The efficacy of aggressive warming combined with tranexamic acid during total hip arthroplasty: a single-center retrospective study from southern China. ( Huang, WW; Huang, X; Huang, Y; Li, FL; Liu, WH; Mo, BF; Yin, D, 2023)
"However, hemarthrosis is the most common complication in arthroscopic surgery, which has potential adverse effects on postoperative rehabilitation."1.91Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study. ( Chen, G; Fu, W; Li, J; Li, Q; Tang, X; Xiong, Y; Yao, L; You, M, 2023)
"Tranexamic acid (TXA) has been popularized as an adjunct to decrease the risk of bleeding and subsequent bruising and edema in aesthetic surgery."1.91Wound Healing Complications With Tranexamic Acid: Not the Silver Bullet After All. ( Auersvald, A; Azizzadeh, B; Frankel, AS; Talei, B; Yalamanchili, S, 2023)
"The primary outcomes were postoperative blood loss and the composite incidence of mortality and morbidities during hospitalization."1.91The efficacy and safety of intravenous administration of tranexamic acid in patients undergoing cardiac surgery: Evidence from a single cardiovascular center. ( He, LX; Jiang, JJ; Lin, PS; Ma, J; Tian, LJ; Yao, YT; Yu, YP; Zhang, Y, 2023)
" The following guidelines provide updated recommendations based on the current state of knowledge on TXA optimal timing, routes of administration and dosing regimen."1.91Die perioperative Gabe von Tranexamsäure. ( Kaufner, L; Lier, H; Perka, C; Treskatsch, S; von Heymann, C, 2023)
"Tranexamic acid (TXA) has long been the antifibrinolytic hemostatic drug of choice for orthopedic surgery."1.91Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs. ( Haibier, A; Qin, Q; Ran, J; Ren, Z; Yusufu, A; Zhang, Z; Zhou, Y, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce blood loss following surgery."1.91Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection. ( Foster, D; Garner, H; Goulding, K; Houdek, M; Sebro, R; Spaulding, AC; Stanborough, R; Wilke, B, 2023)
" Weight-based administration of tranexamic acid (TXA) has the potential to reduce blood loss and related complications in spinal surgery; however, evidence for standardized dosing is lacking."1.91Examining the safety profile of a standard dose tranexamic acid regimen in spine surgery. ( Adida, S; Dalton, J; Fourman, MS; Lee, JY; Mirvish, A; Sadhwani, S; Setliff, J; Shaw, JD; Tang, MY; Wawrose, R, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic drug that reduces blood loss in patients that undergo Total knee arthroplasty (TKA)."1.91Benefits of Tranexamic Acid in Total Knee Arthroplasty: A Classification and Regression Tree Analysis in Function of Instrumentation, BMI, and Gender. ( Carvalho, MM; Cruz, H; Fontes, AP; Marreiros, A; Oliveira, T; Pereira, EG; Sacramento, T; Sousa, JP; Viegas, R, 2023)
"Tranexamic acid (TXA) is an antifibrinolytic agent for reducing blood loss and allogenic blood transfusion."1.72The Efficiency of Simultaneous Systemic and Topical Use of Tranexamic Acid in Spinal Fusion Surgery. ( Akbas, A; Erdogan, U; Sari, S, 2022)
"001) with no associations with blood exposure or adverse events."1.72Blood conservation outcomes and safety of tranexamic acid in coronary artery bypass graft surgery. ( Chen, W; Hu, S; Wang, E; Wang, Y; Yuan, S; Yuan, X; Zhou, X, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic drug that has achieved significant reduction in perioperative blood loss and the quantity of blood transfused in many pediatric surgical procedures, without morbidity."1.72Importance of tranexamic acid in pediatric monosutural craniosynostosis surgery. ( Aillet, S; Aouaissia, S; Delahaye Larralde, S; Eustache, G; Nardi, N; Riffaud, L; Rousseau, C; Wodey, E, 2022)
"Tranexamic acid (TXA) has gained increasing recognition as a valuable pharmacologic agent within plastic surgery."1.72Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty. ( Alsayed, A; Antezana, L; Banuelos, J; Curiel, D; Harless, CA; Kerivan, L; Kuruoglu, D; Martinez-Jorge, J; Nguyen, MT; Sharaf, BA; Tran, NV; Vijayasekaran, A; Weissler, JM, 2022)
"Tranexamic acid (TXA) has shown to significantly reduce perioperative blood loss in elective orthopedic joint replacement surgery but is yet not implemented in acute hip fracture surgery for elderly patients who are particularly vulnerable to perioperative blood loss and postoperative anemia."1.72Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients. ( de Jong, L; Kuijper, TM; Roukema, GR; van Rijckevorsel, VAJIM, 2022)
"Tranexamic acid (TXA) is a synthetic lysine analog that reduces perioperative blood loss by blocking lysine-binding sites on plasminogen molecules."1.72Local tranexamic acid reduces surgical blood loss. ( Bolton, L, 2022)
"Intraoperative blood loss and postoperative drain collection of the TXA group, ANH combined with TXA group were statistically lower than those in the control group and ANH group (P < 0."1.72Acute normovolemic hemodilution in combination with tranexamic acid is an effective strategy for blood management in lumbar spinal fusion surgery. ( Fang, X; Li, Y; Zhang, Y, 2022)
"Tranexamic acid (TXA) has been used to treat severe bleeding events for nearly 60 years and is on the list of World Health Organization essential medicines."1.72Editorial Commentary: The Current Evidence in Support of Tranexamic Acid in Arthroscopic Surgery Is Poor. ( Hohmann, E, 2022)
"To assess the efficacy and safety of hypotensive anesthesia (HA) combined with tranexamic acid (TXA) for reducing perioperative blood loss in simultaneous bilateral total hip arthroplasty (SBTHA)."1.72Hypotensive Anesthesia Combined with Tranexamic Acid Reduces Perioperative Blood Loss in Simultaneous Bilateral Total Hip Arthroplasty: A Retrospective Cohort Study. ( Huang, K; Liao, R; Wang, MY; Xie, HQ; Yang, J; Yin, SJ; Zeng, Y; Zhang, QY, 2022)
"Tranexamic acid (TXA) has been shown to decrease perioperative blood loss, transfusions, and cost in patients undergoing resection of aggressive bone tumors and endoprosthetic reconstruction."1.72Tranexamic acid improves early postoperative mobilization in cancer patients undergoing endoprosthetic reconstruction. ( Bombardier, B; Haase, DR; Kimbrel, B; Mersereau, EJ; Rosenthal, HG; Sweeney, KR; Templeton, KJ, 2022)
" However, both the cause of this and the appropriate measures to determine antifibrinolytic efficacy during high-blood-loss spine surgery are unknown, making clinical trials to optimize antifibrinolytic dosing in PSF difficult."1.72Variable Response to Antifibrinolytics Correlates with Blood-loss and Transfusion in Posterior Spinal Fusion. ( Benvenuti, TA; Borst, AJ; Duvernay, MT; Emerson, BR; Gibson, BHY; Martus, JE; McKeithan, LJ; Mencio, GA; Moore-Lotridge, SN; Schoenecker, JG; Warhoover, TA, 2022)
" To date, the most efficacious dosing protocol in this setting has not yet been ascertained."1.72No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA. ( Bugbee, WD; Copp, SN; Evans, AS; Ezzet, KA; McCauley, JC; Rosen, AS; Walker, RH; Wilde, JM, 2022)
"Tranexamic acid (TXA) has rapidly gained popularity in aesthetic surgery."1.72Local Infiltration of Tranexamic Acid During Facelift Improves Operating Room Efficiency: A Matched Patient Study. ( Coombs, DM; Jin, A; Kwiecien, GJ; Sinclair, NR; Zins, JE, 2022)
"This study aimed to evaluate the efficacy and safety of intravenous combined with topical application of tranexamic acid (TXA) in reducing blood loss in opening wedge high tibial osteotomy (OWHTO)."1.72Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss in opening wedge high tibial osteotomy procedure: A retrospective case-control study. ( Fu, X; Huang, JM; Luo, W; Ma, XL; Wu, J, 2022)
"The aim of the study is to compare weight-based versus standard dosing of intravenous (IV) tranexamic acid (TXA) for blood loss and transfusion amount in total knee arthroplasty (TKA) without a tourniquet."1.72Comparison of weight-based versus standard dosing of tranexamic acid for blood loss and transfusion amount in knee arthroplasty without tourniquet. ( Çarkcı, E; Çerci, MH; Guler, O; Gümüşsuyu, G; Öztürk, Ç, 2022)
"This study suggests that TXA administration safely and effectively reduces blood loss, in particular for wide resection, with no increase in the rate of adverse events."1.72Efficacy and safety of tranexamic acid in patients undergoing surgery for bone and soft tissue tumors: a propensity score matching analysis. ( Endo, M; Fujiwara, T; Iida, K; Matsumoto, Y; Nabeshima, A; Nakashima, Y; Oyama, R; Setsu, N, 2022)
"Tranexamic acid (TXA) has been shown to be effective at reducing peri-operative blood loss and haemarthrosis in arthroplasty and arthroscopic soft tissue reconstructions."1.72Cytotoxicity of tranexamic acid to tendon and bone in vitro: Is there a safe dosage? ( Bolam, SM; Callon, KE; Coleman, B; Cornish, J; Dalbeth, N; Konar, S; Monk, AP; Munro, JT; Musson, DS; O'Regan-Brown, A, 2022)
"Ninety-two hemophilia A patients who underwent total knee arthroplasty in our center were included."1.72Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors. ( Lv, SJ; Shen, SN; Tong, PJ; Wu, DX, 2022)
" However, concerns regarding potential adverse reactions, specifically postoperative seizures and thrombotic events, still exist."1.72Evaluation of the safety of tranexamic acid use in pediatric patients undergoing spinal fusion surgery: a retrospective comparative cohort study. ( Chang, PS; Chatterjee, A; Geiselmann, MT; Ivasyk, I; Jordan, C; Kamel, H; Khormaee, S, 2022)
" Weight-based TXA dosing regimens have been compared to fixed-dose regimens of EACA with variable outcomes in perioperative blood product transfusions and chest tube output."1.72Comparison of trauma-dosed tranexamic acid versus aminocaproic acid in cardiac surgery in the setting of drug shortage. ( Cook, BM; Dannemiller, RE; Goodberlet, MZ; Kelly, JM; Knowles, DM; Malloy, R, 2022)
" The intervention increased the use of TXA for both TKA and THA and shifted the dosage to better align with evidence-based practice guidelines."1.72The effectiveness of a multifaceted, group-facilitated audit and feedback intervention to increase tranexamic acid use during total joint arthroplasty. ( Baghirzada, L; Burak, KW; Cooke, LJ; Dowling, SK; Endersby, RVW; Gjata, I; Law, S; Olivieri, L; Solbak, NM; Weaver, CGW, 2022)
"Tranexamic acid (TXA) has been proven to reduce perioperative blood loss and the incidence of allogeneic blood transfusion in total joint arthroplasty (TJA)."1.72Combination effect of intraoperative and postoperative intravenous tranexamic acid in hip hemiarthroplasty. A propensity score matched analysis. ( Chang, Q; Li, C; Li, Y; Zhang, W, 2022)
" 'Consideration of tranexamic acid use' should be included in the safe surgery checklist."1.72Tranexamic acid for safer surgery: the time is now. ( Grocott, MPW; Murphy, M; Roberts, I; Sayers, R; Toh, CH, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic drug that can be used to treat and prevent bleeding."1.72 ( Bosselmann, K; Keck, M; Lohmeyer, JA; Müller-Wittig, S; Wittig, KS, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic agent that has been increasingly used in THA in recent years to reduce blood loss and the need for transfusion."1.72The Effect of Systemic Tranexamic Acid on Blood Loss and Blood Transfusion Requirement in Elective Total Hip Arthroplasty. ( Akalın, Y; Avcı, Ö; Çevik, N; Öztürk, A; Sağlıcak, H; Şahin, H, 2022)
"The use of tranexamic acid is effective in reduction of blood loss and rates of blood transfusion, without an apparent increase in adverse thromboembolic events."1.72Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients. ( AlSumadi, M; Ashour, R; Banim, R; Kharma, L; Mahmood, A; Whittam, D, 2022)
" The estimated bioavailability for intra-articular administration was 81%."1.72Population Pharmacokinetics of Intra-articular and Intravenous Administration of Tranexamic Acid in Patients Undergoing Total Knee Replacement. ( Aguilera Roig, X; González Osuna, A; Lamas, C; Martínez-Zapata, MJ; Pla-Junca, F; Rojas, LF; Valle, M; Videla, S, 2022)
"To evaluate the effectiveness and safety of tranexamic acid (TXA) combined with intraoperative controlled hypotension (ICH) for reducing perioperative blood loss in primary total hip arthroplasty (THA)."1.62[Effectiveness and safety of tranexamic acid combined with intraoperative controlled hypotension on reducing perioperative blood loss in primary total hip arthroplasty]. ( Huang, K; Liao, R; Wang, M; Xie, H; Yang, J; Yin, S; Zeng, Y; Zhang, Q, 2021)
"Tranexamic acid (TXA) has been shown to reduce blood loss and postoperative transfusions in total knee arthroplasty (TKA)."1.62One Versus Two Doses of Intravenous Tranexamic Acid in Total Knee Arthroplasty. ( Bernstein, JA; Charette, RS; Kamath, AF; Nchako, CM; Nelson, CL; Sloan, M, 2021)
"Nineteen patients had metopic synostosis, 11 had unicoronal synostosis, and 6 had bicoronal synostosis."1.62A protocol of situation-dependent transfusion, erythropoietin and tranexamic acid reduces transfusion in fronto-orbital advancement for metopic and coronal craniosynostosis. ( Chinnadurai, S; Escher, PJ; Kearney, SL; Kebriaei, MA; Linabery, AM; Petronio, JA; Tibesar, RJ; Tu, AD, 2021)
"Tranexamic acid (TXA) has been shown to decrease blood loss and transfusion in shoulder arthroplasty."1.62Intravenous tranexamic acid vs. topical thrombin in total shoulder arthroplasty: a comparative study. ( Anakwenze, O; Belay, ES; Flamant, E; Hinton, Z; Klifto, CS; O'Donnell, J, 2021)
"Tranexamic acid (TXA) has been shown to reduce blood loss and transfusion risk in various orthopedic surgeries including shoulder arthroplasty."1.62Administration of tranexamic acid during total shoulder arthroplasty is not associated with increased risk of complications in patients with a history of thrombotic events. ( Cagle, PJ; Carbone, A; Chan, J; Galatz, LM; Mazumdar, M; Parsons, BO; Poeran, J; Zubizarreta, N, 2021)
"Despite its widespread use, a single formulation or dosing regimen of tranexamic acid (TXA) has not been universally agreed on for total joint arthroplasty."1.62One Dose Versus Two Doses of Intravenous Tranexamic Acid in Total Joint Arthroplasty. ( Adams, WH; Brown, NM; Davis, BJ; Golz, AG; Yee, HK, 2021)
" The exact mechanisms and ideal dosage by which TXA can contribute to such a reduction need further study."1.62Tranexamic Acid Administration is Associated With a Decreased Odds of Prosthetic Joint Infection Following Primary Total Hip and Primary Total Knee Arthroplasty: A National Database Analysis. ( Hong, GJ; Liu, J; Memtsoudis, SG; Wilson, LA, 2021)
"Tranexamic acid (TXA) has proven to be safe in elective and traumatic femoral hemiarthroplasty; however, its use has not been investigated in oncologic patients."1.62Use of tranexamic acid is not associated with complications following bipolar hemiarthroplasty for metastatic disease. ( Houdek, MT; Owen, A; Rose, PS; Wellings, EP; Wyles, CC; Yuan, BJ, 2021)
"Tranexamic acid (TXA) has proven to be effective in reducing the blood loss associated with total knee arthroplasty (TKA) in patients with osteoarthritis."1.62Is there a role of tranexamic acid in rheumatoid arthritis with total knee arthroplasty? Findings from a multicenter prospective cohort study in China. ( Huang, Q; Huang, W; Lei, Y; Pei, F; Xie, J, 2021)
" Nous avons décrit le pourcentage de patients qui ont reçu de l’ATX par chirurgie individuelle, les détails du dosage de l’ATX, et avons estimé l’effet des anesthésiologistes et des chirurgiens sur l’ATX prophylactique en réalisant des analyses de régression logistique multivariées à effets mixtes."1.62Variation in prophylactic tranexamic acid administration among anesthesiologists and surgeons in orthopedic surgery: a retrospective cohort study. ( Ariano, R; Balshaw, R; Blankstein, A; Bohm, E; Breau, RH; Falk, J; Fergusson, DA; Garland, A; Houston, BL; Houston, DS; Jacobsohn, E; Krupka, E; McIsaac, DI; Perelman, I; Rimmer, E; Tinmouth, A; Turgeon, AF; Zarychanski, R, 2021)
" Thus, we conclude that it is safe to use TXA in this patient group."1.62Is tranexamic acid use in patients with a hip fracture safe? ( Andersen, LR; Clemmensen, SB; Gundtoft, PH; Halekoh, U; Lauritsen, J; Madsen, CF; Overgaard, S; Pedersen, L; Schønnemann, JO; Titlestad, K; Viberg, B, 2021)
" For each surgery, we evaluated the percentage of patients who received TXA as well as the specifics of TXA dosing and administration."1.62Prophylactic tranexamic acid use in non-cardiac surgeries at high risk for transfusion. ( Ariano, RE; Balshaw, R; Breau, RH; Falk, J; Fergusson, DA; Garland, A; Houston, BL; Houston, DS; Jacobsohn, E; Krupka, E; McIsaac, DI; Perelman, I; Rimmer, E; Tinmouth, A; Turgeon, AF; Zarychanski, R, 2021)
"0, was employed to analyze demographics including surgical traits, blood loss, drainage, length of hospital stays (LOS), blood biochemical indices, prethrombotic state molecular markers, coagulation function, and adverse events."1.62Safety and Efficacy of Topical Administration of Tranexamic Acid in High-Risk Patients Undergoing Posterior Lumbar Interbody Fusion Surgery. ( Cai, T; Chen, D; Feng, X; Shi, P; Wang, J; Wang, S; Wang, Y; Zhang, L; Zhang, W, 2021)
" The purpose of this study was to determine if TXA is safe to use in patients with a history of CAD or coronary stents."1.62Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty. ( Rozell, JC; Schwarzkopf, R; Sharan, M; Tang, A; Waren, D; Zak, SG, 2021)
"Tranexamic acid (TXA) has been widely used as an antifibrinolytic in dentoalveolar surgery and only recently has its effects been explored in facial procedures."1.62The Use of Tranexamic Acid in Facial Cosmetic Surgery Procedures: A Technical Note. ( Christensen, BJ; Fathimani, K; Perenack, J, 2021)
"Tranexamic acid (TXA) is a drug used to control hemorrhage by preventing the breakdown of fibrin."1.62The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery. ( Egol, KA; Littlefield, CP; Perskin, CR; Umeh, U; Wang, C, 2021)
"Tranexamic acid (TXA) is an effective blood management strategy, as it competitively inhibits the activation process of plasminogen and prevents fibrinolytic enzymes from degrading fibrin."1.62Comparison of topical and intravenous Tranexamic acid for high tibial osteotomy: A retrospective study. ( Bian, J; Deng, B; Li, S; Wang, G; Wang, Z; Yuan, L; Zhang, Y; Zhao, X, 2021)
"Tranexamic acid (TXA) is an anti-fibrinolytic agent whose safety and efficacy in reducing bleeding are well documented."1.56Local Infiltration of Tranexamic Acid With Local Anesthetic Reduces Intraoperative Facelift Bleeding: A Preliminary Report. ( Charafeddine, A; Couto, RA; Nayak, LM; Sinclair, NR; Zins, JE, 2020)
"Tranexamic acid (TXA) has reduced blood transfusion following total hip arthroplasty (THA)."1.56Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty. ( Deckard, ER; Meneghini, RM; Wurtz, JW; Wurtz, LD; Ziemba-Davis, M, 2020)
" The outcomes were evaluated by hidden blood loss (HBL), total blood loss (TBL), intraoperative blood loss (IBL), transfusion rate, maximum hemoglobin (Hb) drop, prethrombotic state molecular markers, liver and renal function, coagulation function, inflammatory factor and adverse events."1.56The efficacy and safety of multiple-dose intravenous tranexamic acid in reducing perioperative blood loss in patients with thoracolumbar burst fracture. ( Cheng, X; Feng, X; Nan, L; Tao, Y; Wang, F; Wang, Y; Yang, J; Zhang, L; Zhang, S, 2020)
" Our study indicates that the local administration of TXA/DEP is safe and more effective than the administration of TXA alone in treating trochanteric femoral fractures."1.56Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures. ( Hu, Y; Xie, L; Xu, X; Yu, H, 2020)
"Tranexamic acid bolus was administered before the skin incision and continued throughout the operation."1.56Perioperative anesthetic management in a patient with factor XI deficiency undergoing coronary artery bypass graft surgery. ( Ince, ME; Ors, N; Ozkan, G; Yildirim, V, 2020)
"Tranexamic acid (TXA) has been used extensively to minimize blood loss in cardiac surgery and more recently in orthopedic surgery."1.56Tranexamic acid administration during total joint arthroplasty surgery is not associated with an increased risk of perioperative seizures: a national database analysis. ( Fiasconaro, M; Kirksey, MA; Liu, J; Memtsoudis, SG; Poeran, J; Wilson, LA, 2020)
"Tranexamic acid (TXA) is a medication that has been shown to decrease blood loss and risk of blood transfusion in total knee and total hip arthroplasty."1.56Effect of Tranexamic Acid on Wound Complications and Blood Loss in Total Ankle Arthroplasty. ( Falcon, S; Haleem, AM; Hollabaugh, K; Luick, L; Ringus, V; Steinmetz, RG; Stoner, J; Tkach, S, 2020)
" Previous studies have established the efficacy of TXA in TKA, however here are limited direct comparison studies available and the dosing regimens vary."1.56Higher doses of topical tranexamic acid safely improves immediate functional outcomes and reduces transfusion requirement in total knee arthroplasty. ( Tan, C; Wang, L; Wu, C, 2020)
"Tranexamic acid is an antifibrinolytic used to counteract blood loss."1.56Effectiveness of administering tranexamic acid to high-risk hip and knee arthroplasty patients: a systematic review protocol. ( Kuster, M; Lockwood, C; Yapa, S, 2020)
"Tranexamic acid (TXA) is an antifibrinolytic agent."1.56The effects of intravenous and local tranexamic acid on bone healing: An experimental study in the rat tibia fracture model. ( Balkanlı, B; Çopuroğlu, C; Çopuroğlu, E, 2020)
"Tranexamic acid use in craniosynostosis surgery has increased dramatically since 2010."1.56Tranexamic Acid in Infantile Craniosynostosis Surgery: Friend or Foe? ( Bennett, WE; Cook, JA; Danforth, RM; Gerety, PA; Tholpady, SS, 2020)
" Perioperative blood loss, vascular events, wound complications, and adverse reactions were compared among the three groups."1.56Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study. ( Li, Z; Lu, Y; Ma, T; Ren, C; Song, L; Wang, Q; Wang, Z; Yang, J; Zhang, B; Zhang, K, 2020)
"There was no significant difference in postoperative blood loss between the tranexamic acid group and the control group."1.56[Analysis of hemostatic effect of intra-articular injection of tranexamic acid after minimally invasive unicompartmental knee arthroplasty]. ( Dong, F; Qian, PK; Sun, BF; Wu, XF; Xu, F; Yin, ZF; Zhang, JB, 2020)
"Patients suffered from acute spinal cord compression caused by spinal tumor manifestation (n = 5), empyema (n = 4), degenerative spinal stenosis (n = 1), hematoma (n = 1), and vertebral body fracture/dislocation (n = 2)."1.51Management of Spinal Emergencies in Patients on Direct Oral Anticoagulants. ( Beynon, C; Gumbinger, C; Olivares, A; Unterberg, AW; Younsi, A; Zweckberger, K, 2019)
"Thirty-four patients with haemophilia A undergoing 24 TKA and 18 THA were evaluated in this retrospective study (No."1.51Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia. ( Huang, Q; Huang, ZY; Ma, J; Pei, FX; Shen, B; Zeng, HJ; Zhou, ZK, 2019)
" A single very low dose of rFVIIa along with TXA is a simple and safe treatment to control hemostasis in severe FXI-deficient patients undergoing diverse type of surgical procedure at various sites."1.51Single Low Dose of rFVIIa Combined with Antifibrinolytic Agent is a Simple and Safe Treatment for Factor XI-Deficient Patients undergoing Surgery. ( Avishai, E; Bashari, D; Budnik, I; Dardik, R; Livnat, T; Salomon, O; Tamarin, I, 2019)
"Tranexamic acid is an antifibrinolytic with proven efficacy in major surgeries."1.51Tranexamic acid in cardiac surgery: a systematic review and meta-analysis (protocol). ( Ainswoth, C; Alaifan, T; Alenazy, A; Belley-Cote, E; Fernando, SM; Fox-Robichaud, A; Karachi, T; Kyeremanteng, K; Rochwerg, B; Spence, J; Whitlock, R; Xiang Wang, D; Zarychanski, R, 2019)
"Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events."1.51Cytotoxicity and effect on wound re-epithelialization after topical administration of tranexamic acid. ( Ausen, K; Eikebrokk, TA; Gravastrand, C; Pukstad, B; Spigset, O; Vassmyr, BS, 2019)
"Tranexamic acid (TXA) is an effective blood salvage agent that reduces perioperative blood loss in conventional total knee arthroplasty (TKA)."1.51Tranexamic Acid Reduces Total Blood Loss and Inflammatory Response in Computer-Assisted Navigation Total Knee Arthroplasty. ( Chou, WY; Hsu, YH; Ko, JY; Kuo, SJ; Siu, KK; Wu, KT, 2019)
"Pediatric craniosynostosis repair with cranial vault reconstructive surgery can be associated with significant blood loss."1.51Ulnar Artery Thrombosis Following Tranexamic Acid Administration for Craniosynostosis Repair. ( Chung, E; Karlberg, HI, 2019)
"Tranexamic acid (TXA) has been shown to reduce blood loss and transfusion requirements in patients undergoing total hip arthroplasty (THA)."1.51Transfusion rates with intravenous tranexamic acid in total hip arthroplasty performed using the direct anterior approach. ( Allen, P; Free, MD; Harvie, P; Owen, DH; Pascoe, E; Yang, L, 2019)
"The incidence of deep vein thrombosis in the topical group (1."1.51Comparison of three routes of administration of tranexamic acid in primary unilateral total knee arthroplasty: Analysis of a national database. ( Hu, Q; Huang, Z; Pei, F; Xie, J; Zhou, Z, 2019)
" The differences concern the systemic and local application, dosage and time of administration."1.51[Evaluation of Efficacy of Systemic Administration of Tranexamic Acid (Exacyl) in Total Hip and Knee Arthroplasty - Prospective Cohort Study]. ( Kubát, P; Longin, P; Mannová, J; Pospíchal, M, 2019)
"Tranexamic acid (TXA) has been shown to significantly reduce transfusion rates in primary total hip arthroplasties (THAs), but high-quality evidence is limited in the revision setting."1.51Intravenous tranexamic acid safely and effectively reduces transfusion rates in revision total hip arthroplasty. ( Abdel, MP; Amundson, AW; Hernandez, NM; Hines, JT; Pagnano, MW; Sierra, RJ, 2019)
" The incidence of adverse events was evaluated in the perioperative period and at 1 month follow-up."1.51Short-term safety of tranexamic acid use in posterior cervical decompression and fusion surgery. ( Burks, JD; Gjolaj, JP; Green, BA; Lugo-Pico, JG; Madhavan, K; Perez-Roman, RJ; Sheinberg, D, 2019)
"Tranexamic acid was used arbitrarily in 36 of them, while the other 47 did not receive TXA."1.51Blood loss and perioperative transfusions related to surgery for spinal tumors. Relevance of tranexamic acid. ( Damade, C; Foulongne, E; Gauthé, R; Gilard, V; Ould-Slimane, M; Tesson, G; Vigny, S, 2019)
" Although previous studies have established the efficacy of tranexamic acid (TXA), data evaluating the widely variable dosing regimens remains sparse."1.51The use of tranexamic acid in adult spinal deformity: is there an optimal dosing strategy? ( Buckland, AJ; Errico, TJ; Raman, T; Varlotta, C; Vasquez-Montes, D, 2019)
"Tranexamic acid (TXA) was found to be more effective at reducing total blood loss compared with epsilon-aminocaproic acid (AM) than placebo."1.48Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice? ( Asghar, J; Lonner, BS; Newton, PO; Ren, Y; Samdani, AF; Shah, SA, 2018)
"Tranexamic acid (TA) is an antifibrinolytic agent that prevents perioperative blood loss in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA)."1.48Comparison of Oral and Intravenous Tranexamic Acid for Prevention of Perioperative Blood Loss in Total Knee and Total Hip Arthroplasty. ( Allen, B; Cunningham, K; Forsyth, R; Gortemoller, MA; Theiss, K; Tucker, C, 2018)
"Blood loss during craniosynostosis surgery can be substantial, ranging from 20% to 500% of total circulating volume with a high associated risk of transfusion-related adverse events."1.48Perioperative Blood Loss and Transfusion in Craniosynostosis Surgery. ( Eccles, S; Hare, A; Miranda, BH; Ong, J; Park, C; Wormald, J, 2018)
"Consensus does not exist regarding the best dosage regimen for using tranexamic acid (TXA) for patients undergoing open calvarial vault remodeling in craniosynostosis surgery."1.48Craniosynostosis Surgery and the Impact of Tranexamic Acid Dosing. ( Bristol, R; Do, A; Kurnik, NM; Pflibsen, LR; Singh, DJ, 2018)
"Tranexamic acid (TXA) is a potent fibrinolysis inhibitor which has been extensively used at the surgical incision and closure to lower overall blood loss in adult reconstruction surgery."1.48Additional Dose of Intravenous Tranexamic Acid after Primary Total Knee Arthroplasty Further Reduces Hidden Blood Loss. ( Li, ZJ; Zeng, L; Zhao, MW, 2018)
"Tranexamic acid has been shown to be effective in reducing blood loss after total hip replacement."1.48Matched cohort study of topical tranexamic acid in cementless primary total hip replacement. ( Bustamante Suarez de Puga, D; Martínez Gimenez, E; Mas Martinez, J; Morales Santias, M; Sanz-Reig, J; Verdu Román, C, 2018)
"Tranexamic acid (TXA) helps to prevent excessive blood loss during total hip arthroplasty (THA) and total knee arthroplasty (TKA), but the most efficacious dosing protocol has not been ascertained."1.48One Dose of Intravenous Tranexamic Acid Is Equivalent to Two Doses in Total Hip and Knee Arthroplasty. ( Bugbee, WD; Copp, SN; McCauley, JC; Wilde, JM, 2018)
"The combined use of intraarticular topical TXA with rivaroxaban in patients undergoing TKA is a safe and effective method to reduce blood loss, the need for transfusion, and wound complications without elevating the risk of DVT."1.48Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis. ( Kang, MW; Kim, JI; Kim, YT; Lee, JK; Lee, YM, 2018)
"Tranexamic acid usage was associated with decreased blood loss."1.48Patients With Infected Total Hip Arthroplasty Undergoing 2-Stage Exchange Arthroplasty Experience Massive Blood Loss. ( Buckley, P; Goel, R; Parvizi, J; Sterbis, E, 2018)
"The intravenous TXA would reduce postoperative blood loss and transfusion requirements without increasing thromboembolic complications in open-wedge HTO."1.48Tranexamic acid is effective for blood management in open-wedge high tibial osteotomy. ( Bae, SH; Kim, GB; Kim, HJ; Kim, KI, 2018)
"Male appeared to suffer more surgical blood loss than female."1.48Blood loss of total knee arthroplasty in osteoarthritis: an analysis of influential factors. ( Hu, Y; Li, Q; Shi, ZJ; Torsha, TT; Wei, BG; Xiao, J; Zhang, XS, 2018)
" The best administration route and dosage should be further studied."1.48[Preliminary analysis of the effect of different administration routes of tranexamic acid on blood loss after total hip arthroplasty for female femur neck fractures]. ( Lin, ZQ; Luo, GG; Xie, HF; Yao, JC; Zhang, HZ, 2018)
"Tranexamic acid was administered during 62% of the arthroplasties in the ATT+ group and to 90% in the ATT- group."1.48Tranexamic acid use and risk of thrombosis in regular users ofantithrombotics undergoing primary total knee arthroplasty: a prospectivecohort study. ( Fennema, P; Hourlier, H, 2018)
"Tranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery."1.46Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion. ( Chiem, J; Ivanova, I; Jimenez, N; Krengel, W; Parker, A, 2017)
"Tranexamic acid (TXA) has been associated with decreased blood loss and transfusion after total hip arthroplasty (THA) and total knee arthroplasty (TKA)."1.46Process Improvement Project Using Tranexamic Acid Is Cost-Effective in Reducing Blood Loss and Transfusions After Total Hip and Total Knee Arthroplasty. ( Barfield, WR; Demos, HA; Lin, ZX; Pellegrini, VD; Robertson, DC; Wilson, SH, 2017)
"TISSEEL fibrin sealant does not reduce postoperative blood loss or transfusions; however, IV TXA reduced postoperative transfusions compared with TISSEEL and control."1.46An Aprotinin Containing Fibrin Sealant Does Not Reduce Blood Loss in Total Hip Arthroplasty. ( Bohl, DD; Kearns, SM; Kuhar, HN; Levine, BR, 2017)
" Although numerous studies demonstrate the efficacy of intravenous and topical TXA in these patients, few demonstrate the effectiveness and appropriate dosing recommendations of oral formulations."1.46Oral Tranexamic Acid Reduces Transfusions in Total Knee Arthroplasty. ( Fournier, CA; Junghans, RP; Mattingly, DA; Perreault, RE; Talmo, CT, 2017)
"Parameters associated with postoperative blood loss were compared to the prolongation of closure time and medication use."1.46Limitations of Preoperative PFA-200 as a Predictor of Postoperative Blood Loss in Total Knee Arthroplasty: According to Use of Tranexamic Acid. ( Jeon, Y; Kang, SY; Kim, MH; Lee, WI, 2017)
"Tranexamic acid has also been used to decrease blood loss by stabilizing clot formation."1.46Use of a Tourniquet in Total Knee Arthroplasty Causes a Paradoxical Increase in Total Blood Loss. ( Papillon, N; Rees, H; Schnettler, T, 2017)
"This study aimed to compare the efficacy of intravenous administration of tranexamic acid for reducing blood loss in total knee arthroplasty at different dosage time."1.46The Efficacy Comparison of Tranexamic Acid for Reducing Blood Loss in Total Knee Arthroplasty at Different Dosage Time. ( Cai, M; Gong, J; Nie, X; Sun, Q; Yu, X, 2017)
"Tranexamic acid (TXA) has been shown to be effective in reducing blood loss, hemoglobin drop, and blood transfusion in primary total hip arthroplasty."1.46Blood-Sparing Efficacy of Oral Tranexamic Acid in Primary Total Hip Arthroplasty. ( Chang, WY; Lee, QJ; Wong, YC, 2017)
"Intra- and postoperative blood loss was compared between the groups."1.46High-dose tranexamic acid reduces intraoperative and postoperative blood loss in posterior lumbar interbody fusion. ( Iwasaki, M; Kushioka, J; Maeno, T; Matsumoto, T; Okuda, S; Yamasaki, R; Yamashita, T, 2017)
"Tranexamic acid was superior to fibrin sealant in decreasing allogeneic transfusion requirements (0 vs."1.46Tranexamic acid versus fibrin sealant in primary total hip replacement: a comparative study. ( Borbora, A; Kumar, G; Mahmood, A; Peter, V; Sawalha, S, 2017)
"The aim was to utilize the Pediatric Craniofacial Surgery Perioperative Registry database to identify the safety profile of antifibrinolytic therapy for cranial vault reconstructive surgery by reporting the incidence of adverse events as they relate to exposure to tranexamic acid and aminocaproic acid compared to no exposure to antifibrinolytics."1.46Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group. ( Cladis, FP; Fernandez, AM; Glover, CD; Goobie, SM; Huang, H; Reddy, SK; Stricker, PA; Zurakowski, D, 2017)
"Tranexamic acid (TXA) has been reported to demonstrate efficacy in reducing blood loss during arthroplasty procedures."1.43Intravenous administration of tranexamic acid effectively reduces blood loss in primary total knee arthroplasty in a 610-patient consecutive case series. ( Pitta, M; Rubinstein, A; Verstraete, R; Zawadsky, M, 2016)
"Tranexamic acid has been reported to be safer with topical administration than with intravenous administration in total knee arthroplasty."1.43Comparison between topical and intravenous administration of tranexamic acid in primary total hip arthroplasty. ( Fukumori, N; Kawano, S; Kitajima, M; Mawatari, M; Sonohata, M; Ueno, M, 2016)
"Tranexamic acid (TXA) has proven its efficacy in reducing blood loss and the need for blood transfusions in patients who have undergone a total knee arthroplasty (TKA) surgical procedure."1.43Does tranexamic acid reduce blood loss and transfusion rates in unicompartmental knee arthroplasty? ( Pongcharoen, B; Ruetiwarangkoon, C, 2016)
"The incidence of symptomatic deep vein thrombosis and pulmonary embolism was evaluated."1.43Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis. ( Chen, AF; Heller, S; Parvizi, J; Secrist, E; Shahi, A, 2016)
"Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general trauma patients as well as patients undergoing elective orthopaedic surgery."1.43Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients. ( Flores, E; Garner, MR; Gausden, EB; Levack, A; Lorich, DG; Nellestein, AM; Tedore, T; Warner, SJ, 2016)
"Tranexamic acid (TXA) is an antifibrinolytic that blocks lysine-binding sites of fibrinogen and fibrin, preventing the breakdown of existing clots."1.43Tranexamic Acid in Anesthetic Management of Surgical Procedures. ( Alwon, K; Collins, S; Hewer, I; Mayeux, J, 2016)
"Of a total of 259 patients with craniosynostosis, 187 had nonsyndromic single-suture involvement; 69 of these patients (36."1.43Implementation of a Tranexamic Acid Protocol to Reduce Blood Loss During Cranial Vault Remodeling for Craniosynostosis. ( Diggs, B; Esmonde, N; Gries, H; Koh, J; Kuang, AA; Martin, DT; Schreiber, M; Selden, NR, 2016)
" TXA use was also associated with reduced risk of readmission among total hip arthroplasty patients and reduced risk of VTE among total knee arthroplasty patients, and did not have an adverse effect on cardiovascular complications in either group."1.43The Michigan Experience with Safety and Effectiveness of Tranexamic Acid Use in Hip and Knee Arthroplasty. ( Cowen, ME; Hallstrom, B; Hughes, RE; Roberts, KC; Singal, B, 2016)
"Tranexamic acid (TXA) is an antifibrinolytic agent that can be used to reduce blood loss in total knee arthroplasty (TKA) patients."1.43Intraarticular Administration of Tranexamic Acid is Safe and Effective in Total Knee Arthroplasty Patients at High-Risk for Thromboembolism. ( Chughtai, M; Delanois, RE; Gwam, C; Khlopas, A; Mistry, JB; Mont, MA; Mudaliar, PP; Tangri, V; Thomas, M, 2016)
"Tranexamic acid (TXA) is an antifibrinolytic agent that competitively inhibits the activation of plasminogen to plasmin."1.42Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty. ( George, DA; Nwaboku, H; Sarraf, KM, 2015)
"Tranexamic acid (TXA) is a synthetic antifibrinolytic drug that competitively decreases the conversion of plasminogen to plasmin, thereby suppressing fibrinolysis."1.42Evaluating the safety and efficacy of tranexamic acid administration in pediatric cranial vault reconstruction. ( Claiborne, JR; Couture, DE; Crantford, JC; David, LR; Ririe, DG; Thompson, JT; Wood, BC, 2015)
"Tranexamic acid is a safe and effective antifibrinolytic agent used systemically and topically to reduce blood loss and transfusion rate in patients having TKA or THA."1.42Topical tranexamic Acid does not affect electrophysiologic or neurovascular sciatic nerve markers in an animal model. ( Dang, P; Gupta, R; Luu, M; Mozaffar, T; Schwarzkopf, R, 2015)
"Tranexamic acid (TXA) has shown safety and efficacy in reducing blood loss associated with various surgical procedures."1.42Does Tranexamic Acid Reduce Blood Loss and Transfusion Requirements Associated With the Periacetabular Osteotomy? ( Baca, GR; Clohisy, JC; Keith, AD; Schoenecker, PL; Wingerter, SA, 2015)
"A total of 33 children with metopic synostosis were operated on using standardized FOA, of which 16 patients (48."1.42The value of tranexamic acid during fronto-orbital advancement in isolated metopic craniosynostosis. ( Bodem, JP; Busch, CJ; Engel, M; Freudlsperger, C; Hoffmann, J; Horn, D; Mertens, C, 2015)
"Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective lower limb arthroplasty surgery."1.42The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study. ( Edmondson, M; Freeman, R; Lee, C; Rogers, BA, 2015)
"Low-dose IA-TXA application in TKR with prolonged clamping drain method is a safe and effective blood conservative technique with only minimal systemic absorption and without significant increase in systemic absorption over time."1.42An In Vivo Study of Low-Dose Intra-Articular Tranexamic Acid Application with Prolonged Clamping Drain Method in Total Knee Replacement: Clinical Efficacy and Safety. ( Angchaisukisiri, P; Aryurachai, K; Chanplakorn, P; Jittorntam, P; Kawinwonggowit, V; Panpikoon, T; Sa-ngasoongsong, P; Uthadorn, K; Wongsak, S, 2015)
"Although TXA seemed safe and effective in this database review of patients with severe medical comorbidities, a larger prospective trial is warranted to confirm these results."1.40Preliminary results suggest tranexamic acid is safe and effective in arthroplasty patients with severe comorbidities. ( Duncan, C; Gillette, BP; Pagnano, MW; Sierra, RJ; Smith, H; Whiting, DR, 2014)
"Tranexamic acid (TA) has been reported to reduce blood loss after total joint arthroplasty; however, the literature is sparse in evaluating its efficacy in simultaneous bilateral total knee arthroplasty (TKA)."1.40Evaluation of the efficacy and safety of tranexamic acid for reducing blood loss in bilateral total knee arthroplasty. ( Bloomfield, MR; DiIorio, TM; Irizarry, AM; Karam, JA; Sharkey, PF, 2014)
"Tranexamic acid has been used for many years to minimise blood loss during surgery and, more recently, to reduce morbidity after major trauma."1.40Perioperative tranexamic acid in day-case paediatric tonsillectomy. ( Robb, PJ; Thorning, G, 2014)
"Tranexamic acid (TXA) has been used successfully in primary total knee arthroplasty (TKA) to minimize blood loss and transfusions."1.40Decreased blood transfusion following revision total knee arthroplasty using tranexamic acid. ( Falls, TD; Malkani, AL; Samujh, C; Smith, L; Wessel, R, 2014)
"Tranexamic acid was effective in reducing the need for blood transfusions while not increasing the risk of complications, including thromboembolic events and renal failure."1.40Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. ( Boettner, F; Danninger, T; Mazumdar, M; Memtsoudis, SG; Opperer, M; Poeran, J; Rasul, R; Suzuki, S, 2014)
"Tranexamic acid (TA) has been shown to reduce perioperative blood loss and blood transfusion."1.39Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty. ( Duncan, CM; Gillette, BP; Maradit Kremers, H; Pagnano, MW; Sierra, RJ; Smith, HM; Trousdale, RT, 2013)
"Tranexamic acid has been shown to reduce perioperative blood loss without increasing the risk of venous thromboembolism after total knee replacement."1.39Cerebrovascular infarction following bilateral total knee arthroplasty and tranexamic acid administration. ( Baker, J; Bruce-Brand, R; Dragomir, R; Harty, J, 2013)
"Tranexamic acid is an antifibrinolytic drug."1.39Tranexamic acid and thrombosis. ( , 2013)
"Tranexamic acid (TXA) has been proven to be safe and effective in preventing blood loss in primary TKA."1.39One dose of tranexamic acid is safe and effective in revision knee arthroplasty. ( Berta, DM; Howard, JL; Naudie, DD; Ralley, FE; Smit, KM, 2013)
"The tranexamic acid dose was higher in the combined group (5."1.39A retrospective analysis of blood loss with combined topical and intravenous tranexamic acid after coronary artery bypass graft surgery. ( Arellano, R; Hamilton, A; Mahaffey, R; Phelan, R; Wang, L, 2013)
" However, few studies have reported the optimum timing and dosage for administration of TXA."1.39Repeat-dose intravenous tranexamic acid further decreases blood loss in total knee arthroplasty. ( Hamada, M; Hideki, Y; Iwai, T; Sugamoto, K; Tomita, T; Tsuji, S, 2013)
"Tranexamic acid has long been used in orthopaedic surgery as an antifibrinolytic agent."1.38[Tranexamic acid reduces blood loss after major elective orthopaedic operations]. ( Eschen, CT; Husted, H; Tengberg, PT; Troelsen, A, 2012)
"Tranexamic acid (TA) is an inexpensive antifibrinolytic agent that is little used in orthopaedic surgery due to the absence of standardised optimal administration regimens."1.38Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery. ( Argenson, JN; Hémon, Y; Irisson, E; Kerbaul, F; Parratte, S; Pauly, V, 2012)
"Average preoperative major deformity (kyphosis or scoliosis) was 97° ± 31°."1.38Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. ( Bastrom, TP; Emans, JB; Lenke, LG; Newton, PO; Shah, SA; Shufflebarger, HL; Sponseller, PD; Sucato, DJ, 2012)
"The rate of avoidance of ABTs, postoperative blood loss, and complications (DVT/PE, skin problems) were examined."1.37Efficient strategy for controlling postoperative hemorrhage in total knee arthroplasty. ( Hoshino, Y; Sasanuma, H; Sekiya, H; Sugimoto, N; Takada, H; Takatoku, K, 2011)
"Blood conservation; the area of greatest clinical variability was seen in dosing regimes for Tranexamic acid."1.37Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice. ( Bird, S; McGill, N, 2011)
"Postoperative seizures occurred significantly more frequently in TXA patients (7."1.37Seizures after open heart surgery: comparison of ε-aminocaproic acid and tranexamic acid. ( Breuer, T; Gertler, R; Knorr, J; Lange, R; Macguill, M; Martin, K; Tassani, P; Wiesner, G, 2011)
"Tranexamic acid was given concomitantly every 8 h."1.37rFVIIa administered by continuous infusion during surgery in patients with severe congenital FVII deficiency. ( Holme, PA; Paus, A; Tjønnfjord, GE; Tran, HT, 2011)
"Its use for craniosynostosis surgery warrants investigation."1.37Comparative analysis of tranexamic acid use in minimally invasive versus open craniosynostosis procedures. ( Istaphanous, G; Martin, D; Maugans, TA; Salisbury, S; Taylor, J, 2011)
"All patients with seizures did not have permanent neurological abnormalities."1.36High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients. ( Burt, C; Chu, M; Falter, F; Granton, J; Murkin, JM; Young, B, 2010)
" However, many of the dosing schedules in these studies are not ideally suited for routine application."1.36One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty. ( Berta, D; Binns, V; Howard, J; Naudie, DD; Ralley, FE, 2010)
" Further confirmatory prospective studies evaluating the efficacy and safety profile of TXA are urgently needed to find a safe dosage for this antifibrinolytic drug."1.36Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis. ( Martiny, V; Rosenthal, C; Sander, M; Spies, CD; von Heymann, C; Wernecke, KD, 2010)
"IV tranexamic acid was also administered to reduce intraoperative blood loss."1.35Routine preoperative coagulation screening detects a rare bleeding disorder. ( Anne, KK; Durga, P; Jonnavithula, N; Pochiraju, R; Ramachandran, G, 2009)
" All the patients received specific hemostasis/coagulation management based on (a) routine use of tranexamic acid, (b) heparin dose-response monitoring, thromboelastography, platelet (PLT) function analysis in a select population of patients, and (c) use of fresh frozen plasma (FFP), PLTs, and desmopressin according to the hemostasis/coagulation profile."1.35Living without aprotinin: the results of a 5-year blood saving program in cardiac surgery. ( Ballotta, A; Castelvecchio, S; Conti, D; Isgrò, G; Ranucci, M; Romitti, F, 2009)
"Glanzmann thrombasthenia is a rare congenital platelet disorder characterized by spontaneous mucocutaneous bleeding and severe bleeding complications during major surgery."1.35Perioperative haemostatic management of Glanzmann thrombasthenia for abdominal surgery. ( Heindl, B; Lison, S; Spannagl, M, 2009)
"However, thrombosis has occurred in three of 12 such patients."1.35Recombinant activated factor VII and tranexamic acid are haemostatically effective during major surgery in factor XI-deficient patients with inhibitor antibodies. ( Bar-Zakay, B; Horowitz, Z; Korianski, Y; Livnat, T; Mor, Y; Salomon, O; Seligsohn, U; Tamarin, I; Winckler, H, 2009)
"The tranexamic acid group has received 30 mg kg-1 the acid tranexamic and the aprotinin group has received a low regimen as 500,000 UIK of aprotinin."1.32[Tranexamic acid versus aprotinin for the prevention of bleeding during mitral valve surgery ]. ( Ait Houssa, M; Amahzoune, B; Arji, M; Azendour, H; Boulahya, A; Elbekkali, Y; Elkirat, A; Ibbat, D; Jabrani, K; Mamoun, F; Selkane, C; Wahid, FA, 2003)
" The goal of this study was to determine if acute normovolemic hemodilution combined with fibrinolytic inhibition and the use of cell saver can reduce the need for homologous blood transfusion in total hip arthroplasty compared to the cellsaver technique alone."1.32[Acute normovolemic hemodilution combined with inhibition of fibrinolysis and use of cell saver in total hip arthroplasty]. ( Erichsen, H; Gravesen, HS; Lauritsen, AØ; Øberg, BL, 2003)
" The dosing of tranexamic acid may require adjustment for renal insufficiency."1.31Plasma tranexamic acid concentrations during cardiopulmonary bypass. ( Dong, Y; Ereth, MH; Fiechtner, BK; Johnson, ME; Nuttall, GA; Oliver, WC; Oyen, LJ; Sarpal, RS; Sujirattanawimol, N, 2001)

Research

Studies (1,488)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's55 (3.70)18.2507
2000's133 (8.94)29.6817
2010's721 (48.45)24.3611
2020's579 (38.91)2.80

Authors

AuthorsStudies
Jozefowicz, E1
Sabourdin, N1
Lambelin, V1
Lejeune, V1
Delassus, R1
Tavernier, B1
Cho, MR1
Jun, CM1
Song, SK1
Choi, WK2
Peng, HM2
Wang, W4
Lin, J2
Weng, XS1
Qian, WW1
Wang, WD1
Laikhter, E1
Comer, CD1
Shiah, E1
Manstein, SM1
Bain, PA1
Lin, SJ1
Kuo, CC1
DeGiovanni, JC1
Carr, MM1
Zhang, Q4
Yin, S2
Huang, K2
Wang, M2
Xie, H4
Liao, R3
Zeng, Y12
Yang, J13
Shodipo, OM1
Jatto, HI1
Ramat, AM1
Ibrahim, SS1
Ajiboye, LO1
Arojuraye, SA1
James, JA1
Toluse, AM1
Chen, C8
Liu, J20
Du, L1
Lee, MJ1
Kim, JK2
Tang, J2
Ming, JM1
Chua, ME1
Haase, DR2
Kimbrel, B2
Bombardier, B2
Templeton, KJ2
Rosenthal, HG2
Sweeney, KR2
Afzali, SL1
Panahi, H1
Ganji, F1
Ziaei, S1
Sedaghat, N1
Magill, P3
Hill, JC2
Bryce, L3
Martin, U3
Dorman, A3
Hogg, R3
Campbell, C3
Gardner, E3
McFarland, M3
Bell, J4
Benson, G3
Beverland, D3
Luo, Y4
Releken, Y2
Yang, D1
Yue, Y2
Liu, Z2
Kang, P8
Jiang, W4
Fu, M5
Dong, W1
Zhou, N1
Shen, J5
Zhang, X11
Hao, J2
Schwaiger, M1
Wallner, J1
Zemann, W1
Aichner, S1
Zrnc, T1
Metzler, P1
Ikwuezunma, IA1
Margalit, A1
Sponseller, PD4
Sandler, N1
Ho, H1
Draxler, DF1
Bain, CR1
Smith, JA2
Hauser, CJ1
Gruen, RL3
Myles, PS3
Medcalf, RL1
Siemens, K1
Sangaran, DP1
Hunt, BJ3
Murdoch, IA1
Tibby, SM1
Ahlers, CG1
Lan, M1
Schoenecker, JG2
Borst, AJ3
Goldstein, K1
Jones, C1
Kay, J1
Shin, J1
de Sa, D1
Alsubaie, HM1
Abu-Zaid, A4
Sayed, SI1
Pathak, KA1
Almayouf, MA1
Albarrak, M1
Aldhahri, SF1
Al-Qahtani, KH1
Azboy, I1
Cheng, JF1
Qian, WQ1
Yishake, M1
Shen, JW1
Pan, Z1
Xu, T1
Masouros, P3
Antoniou, G1
Nikolaou, VS3
Yap, D1
Shakir, A1
Hunt, A1
Liu, W6
Deng, S1
Liang, J2
Örs, Ç1
Çaylak, R1
Brown, NJ2
Choi, EH2
Gendreau, JL2
Ong, V2
Himstead, A1
Lien, BV1
Shahrestani, S2
Ransom, SC1
Tran, K1
Tafreshi, AR1
Sahyouni, R2
Chan, A1
Oh, MY1
Wang, Z9
Huang, Q19
Liu, L1
Lu, Y3
Zhang, C7
Ma, T5
Li, Z11
Wang, Q13
Xue, H3
Zhang, K4
Koh, A2
Adiamah, A2
Gomez, D2
Sanyal, S2
Sun, X5
Li, W7
Zhang, M2
Atasever, AG1
Eerens, M1
Van den Eynde, R1
Faraoni, D6
Rex, S1
Erdogan, U1
Sari, S1
Akbas, A1
Xu, H10
Xie, J18
Huang, Z11
Wang, D12
Pei, F27
Emrah, K1
Ali, AH1
Utku, O1
Murat, K1
Kenan, S1
Deniz, B1
Maethungkul, R1
Atthakomol, P1
Phinyo, P1
Phanphaisarn, A1
Murakami, H1
Sangsin, A1
Öztürk, A5
Akalin, Y5
Çevik, N5
Avcı, Ö3
Çetin, O1
Sağlicak, H4
Hourlier, H3
Fennema, P3
MacDonald, M1
Ilie, G1
Power, L1
Whalen, S1
Parker, R1
Skinner, TA1
Powers, AGL1
Sarpong, NO2
Chiu, YF3
Rodriguez, JA2
Boettner, F10
Westrich, GH3
Chalmers, BP7
Yee, DK1
Wong, JSH1
Fang, E1
Wong, TM1
Fang, C2
Leung, F1
Viberg, B2
Lei, Y11
Liao, J2
Liang, X3
Hu, N3
Huang, W12
Wang, E2
Yuan, X5
Wang, Y21
Chen, W2
Zhou, X3
Hu, S3
Yuan, S4
Hanreich, C2
Cushner, F2
Krell, E1
Gausden, E1
Cororaton, A2
Gonzalez Della Valle, A5
Zins, JE5
Dutton, JW2
Ausen, K3
Eikebrokk, T1
Vassmyr, B1
Gravastrand, C2
Spigset, O3
Pukstad, B2
Wang, F8
Wang, SG1
Yang, Q2
Nan, LP1
Cai, TC1
Wu, DS1
Zhang, L12
Morris, JL2
Letson, HL2
McEwen, P2
Biros, E1
Dlaska, C1
Hazratwala, K2
Wilkinson, M2
Dobson, GP2
Huang, L2
Li, P1
Gu, X1
Zhao, R1
Ma, X4
Wei, X1
Takahashi, R1
Kajita, Y1
Iwahori, Y1
Harada, Y1
Zapata-Copete, JA1
Gómez-Ospina, JC1
García-Perdomo, HA1
Caycedo, DJ1
Eustache, G2
Nardi, N1
Rousseau, C1
Aouaissia, S1
Aillet, S1
Delahaye Larralde, S1
Wodey, E1
Riffaud, L2
K S, A1
Kumar, P1
Subair, M1
Sharma, RK1
Xie, Q1
Huang, CJ1
Gu, KP1
Yao, YX1
Wilson, B1
Yang, CY1
Himstead, AS1
Shlobin, NA1
Reardon, T1
Birkenbeuel, J1
Cohn, SJ1
Yang, I1
Su, E1
Lyman, S2
Jungwirth-Weinberger, A2
Violette, PD1
Compton, E1
Goldstein, RY1
Nazareth, A1
Shymon, SJ1
Andras, L1
Kay, RM1
Weissler, JM2
Kuruoglu, D1
Antezana, L1
Curiel, D1
Kerivan, L1
Alsayed, A1
Banuelos, J2
Harless, CA1
Sharaf, BA1
Vijayasekaran, A1
Martinez-Jorge, J1
Tran, NV2
Nguyen, MT1
Sun, C1
Ma, Q1
Tu, Y1
Cai, X1
Zhou, Y4
Binyamin, Y1
Orbach-Zinger, S1
Gruzman, I1
Frenkel, A1
Lerman, S1
Zlotnik, A1
Frank, D1
Ioscovich, A1
Erez, O1
Heesen, M1
Baccaglini, W1
Rodrigues, AF1
Glina, FPA1
DallAqua, V1
Glina, S1
Neto, ACL1
Wang, H10
Wu, X4
van Rijckevorsel, VAJIM1
Roukema, GR1
Kuijper, TM1
de Jong, L1
Marcucci, M3
Painter, TW2
Conen, D1
Leslie, K2
Lomivorotov, VV1
Sessler, D1
Chan, MTV1
Borges, FK1
Martínez Zapata, MJ1
Wang, CY3
Xavier, D1
Ofori, SN1
Landoni, G3
Efremov, S1
Kleinlugtenbelt, YV1
Szczeklik, W1
Schmartz, D1
Garg, AX1
Short, TG1
Wittmann, M1
Meyhoff, CS1
Amir, M1
Torres, D1
Patel, A1
Duceppe, E1
Ruetzler, K1
Parlow, JL1
Tandon, V1
Wang, MK1
Fleischmann, E1
Polanczyk, CA1
Jayaram, R1
Astrakov, SV1
Rao, M1
VanHelder, T2
Wu, WKK1
Cheong, CC2
Ayad, S1
Abubakirov, M1
Kirov, M1
Bhatt, K1
de Nadal, M1
Likhvantsev, V1
Iglesisas, PP1
Aguado, HJ1
McGillion, M1
Lamy, A2
Whitlock, RP1
Roshanov, P1
Stillo, D1
Copland, I1
Vincent, J1
Balasubramanian, K2
Bangdiwala, SI1
Biccard, B1
Kurz, A1
Srinathan, S1
Petit, S1
Eikelboom, J1
Richards, T2
Gross, PL1
Alfonsi, P2
Guyatt, G2
Belley-Cote, E2
Spence, J2
McIntyre, W1
Yusuf, S1
Devereaux, PJ2
Bolton, L1
Li, S12
Yan, X2
Li, R3
Zeng, M4
Dong, J1
Wang, J19
Liu, X4
Peng, Y4
Li, Y9
Zhang, Y15
Fang, X1
Hohmann, E1
Zhang, QY1
Yin, SJ1
Wang, MY1
Xie, HQ1
Ebrahim Soltani, Z1
Hanaei, S1
Dabbagh Ohadi, MA1
Maroufi, SF1
Tayebi Meybodi, K1
Khademi, S1
Yaghmaei, B1
Ebrahim Soltani, A1
Nejat, F1
Habibi, Z1
Ma, J18
Zhou, Z10
Shen, B16
Shah, N1
Khetan, V1
Sivanadan, H1
Cohen-Levy, WB2
Klemt, C1
Tirumala, V1
Burns, JC1
Barghi, A1
Habibi, Y1
Kwon, YM1
Fossmark, R1
Pleym, H2
Karanicolas, PJ4
Lin, Y5
McCluskey, S1
Roke, R2
Tarshis, J2
Thorpe, KE1
Ball, CG1
Chaudhury, P1
Cleary, SP1
Dixon, E1
Eeson, G1
Moulton, CA1
Nanji, S1
Porter, G1
Ruo, L1
Skaro, AI1
Tsang, M1
Wei, AC1
Mersereau, EJ1
Puri, S1
Sculco, PK6
Zou, ZY1
He, LX3
Yao, YT4
Aboul-Fotouh, S1
Habib, MZ1
Magdy, SM1
Hassan, BEE1
Gibson, BHY1
Duvernay, MT1
McKeithan, LJ1
Benvenuti, TA1
Warhoover, TA1
Martus, JE1
Mencio, GA1
Emerson, BR1
Moore-Lotridge, SN1
Zha, GC1
Zhu, XR1
Wang, L14
Li, HW1
Lier, H3
Kammerer, T3
Knapp, J2
Hofer, S2
Maegele, M2
Fries, D2
von Heymann, C4
Eaker, L1
Selverian, SR1
Hodo, LN1
Gal, J1
Gangadharan, S1
Meyers, J1
Dolgopolov, S1
Lonner, B2
Shalaby, MA1
Maged, AM2
Al-Asmar, A1
El Mahy, M1
Al-Mohamady, M1
Rund, NMA1
Kim, CH2
Lim, EJ1
Kim, S2
Kim, JW1
Wilde, JM2
Copp, SN2
Ezzet, KA1
Rosen, AS1
Walker, RH1
McCauley, JC2
Evans, AS1
Bugbee, WD2
Berg, AJ1
Naylor, T1
Johnson, DS1
Zhang, Z8
Li, J17
Huang, B1
Jiang, Z3
Pan, Y1
He, T1
Hu, Y4
Tapking, C1
Hundeshagen, G1
Kirchner, M1
Fischer, S1
Kneser, U1
Bliesener, B1
Bierke, S1
Häner, M1
Bentzin, M1
Park, HU1
Petersen, W1
Coombs, DM3
Kwiecien, GJ2
Sinclair, NR3
Jin, A1
Xiao, K1
Zhuo, X1
Peng, X1
Wu, Z3
Li, B1
Akti, S1
Zeybek, H1
Bilekli, AB1
Çelebi, NÖ1
Erdem, Y1
Çankaya, D2
Okuzu, Y1
Goto, K1
Kuroda, Y1
Kawai, T1
Matsuda, S1
Achour, I1
Ben Rhaiem, Z1
Thabet, W1
Jdidi, J1
Mnejja, M1
Hammami, B1
Chakroun, A1
Charfeddine, I1
Tan, TK2
Lee, JY2
Tay, A1
Kuster, M2
Luo, W2
Fu, X4
Huang, JM1
Wu, J9
Ma, XL8
Lim, GB1
Qu, W1
Zhou, H2
Tian, P3
Qin, X1
Shen, W1
Zhang, D1
Kong, Q1
Zhang, B5
Feng, P1
Wu, Y12
Guo, C1
Fowler, H1
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Tham, SM1
Gunaravi, SA1
Houghton, N1
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Petersson, C1
Fredin, H2
Karski, JM3
Teasdale, SJ4
Norman, P1
Carroll, J2
VanKessel, K1
Wong, P1
Glynn, MF5
Penta de Peppo, A1
Pierri, MD1
Scafuri, A1
De Paulis, R1
Colantuono, G1
Caprara, E1
Tomai, F1
Chiariello, L1
Couto, WJ1
Gregori Júnior, F1
Cordeiro, CO1
Silva, SS1
Ketzer, JL1
Silva, L1
Rosa, V1
Freitas, M1
Wanderley, WR1
Hiippala, S1
Strid, L1
Wennerstrand, M1
Arvela, V1
Mäntylä, S1
Ylinen, J1
Niemelä, H1
Horrow, JC1
Van Riper, DF1
Strong, MD1
Grunewald, KE1
Parmet, JL1
Rousou, JA1
Engelman, RM1
Flack, JE1
Deaton, DW1
Owen, SG1
Norman, PH1
Carroll, JA1
Weisel, RD2
Borea, G1
Montebugnoli, L1
Capuzzi, P1
Magelli, C1
Rubens, F1
Wells, P1
Harmon, DE1
Zonis, Z1
Seear, M1
Reichert, C1
Sett, S1
Allen, C1
Menichetti, A1
Tritapepe, L1
Ruvolo, G1
Speziale, G1
Cogliati, A1
Di Giovanni, C1
Pacilli, M1
Criniti, A1
Boylan, JF1
Klinck, JR1
Sandler, AN1
Greig, PD1
Nierenberg, H1
Roger, SL1
Howes, JP1
Cohen, AT1
As, AK1
Hagen, P1
Webb, JB1
Hiippala, ST1
Strid, LJ1
Wennerstrand, MI1
Arvela, JV1
Niemelä, HM1
Mäntylä, SK1
Kuisma, RP1
Ylinen, JE1
Katoh, J1
Tsuchiya, K1
Sato, W1
Nakajima, M2
Iida, Y1
van der Staak, FH1
de Haan, AF1
Geven, WB1
Festen, C1
Reid, RW1
Zimmerman, AA1
Laussen, PC1
Mayer, JE1
Gorlin, JB1
Burrows, FA1
Dryden, PJ2
O'Connor, JP2
Jamieson, WR2
Reid, I1
Ansley, D1
Sadeghi, H2
Burr, LH1
Munro, AI1
Merrick, PM2
Brown, RS1
Thwaites, BK1
Mongan, PD1
Ansley, DM1
Dupont, C1
Harel, F1
Robitaille, D1
Roy, M1
Gagnon, L1
Lambert, W1
Brisebois, FJ1
Wharton, TJ1
Carrier, RC1
Boyle, D1
Rowe, BH1
Bernardoni-Socorro, C1
Arteaga-Vizcaino, M1
Villamizar, Y1
Diez-Ewald, M1
Vizcaíno-Salazar, G1
Torres-Guerra, E1
Quintero, J1
Okuyama, K1
Matsukawa, T1
Abe, F1
Kumazawa, T1
Shimamura, Y1
Hirayama, T1
Misumi, H1
Shimokawa, T1
Uesugi, H1
Uemura, K1
Misfeld, M1
Dubbert, S1
Eleftheriadis, S1
Siemens, HJ1
Sievers, HH1
Dowd, NP1
Joiner, R1
Peniston, C1
Bailey, K1
Cheng, DC1
Bach, KF1
Kjoergaard, J1
Christensen, HR1
Bevan, DH1
Luban, I1
Jedeikin, R2
Guzzon, D2
Oppizzi, M2
Cossolini, M2
Torri, G2
Calori, G3
Levi, M1
Cromheecke, ME1
de Jonge, E1
Prins, MH1
de Mol, BJ1
Briët, E1
Büller, HR1
Jansen, AJ1
Andreica, S1
Claeys, M1
D'Haese, J1
Camu, F1
Jochmans, K1
De Bonis, M1
Cavaliere, F1
Alessandrini, F1
Lapenna, E1
Santarelli, F1
Moscato, U1
Schiavello, R1
Possati, GF1
Nuttall, GA2
Oliver, WC2
Ereth, MH2
Santrach, PJ1
Bryant, SC1
Orszulak, TA1
Schaff, HV1
Cvachovec, K1
Horácek, M1
Vislocký, I1
Martin-Hirsch, PL1
Kitchener, H1
Coker, N1
Higgins, DJ1
Dalmau, A1
Sabaté, A1
Acosta, F1
Garcia-Huete, L1
Sansano, T1
Rafecas, A1
Figueras, J1
Jaurrieta, E1
Parrilla, P1
Cattaneo, M1
Innerhofer, P1
Kühbacher, G1
Schobersberger, W1
Bellotti, F1
Ido, K1
Neo, M1
Asada, Y1
Kondo, K1
Morita, T1
Sakamoto, T1
Hayashi, R1
Kuriyama, S1
Tagariello, G1
De Biasi, E1
Gajo, GB1
Risato, R1
Radossi, P1
Davoli, PG1
Traldi, A1
Ekbäck, G1
Axelsson, K1
Ryttberg, L1
Edlund, B1
Kjellberg, J1
Weckström, J1
Carlsson, O1
Schött, U1
Miyashita, T1
Kamibayashi, T1
Kuro, M1
Nitu-Whalley, IC1
Griffioen, A1
Harrington, C1
Lee, CA1
Fiechtner, BK1
Johnson, ME1
Sujirattanawimol, N1
Sarpal, RS1
Oyen, LJ1
Armellin, G1
Casella, S1
Guzzinati, S1
Pasini, L1
Marcassa, A1
Giron, G1
Murto, K1
Hall, L1
Barrowman, NJ1
Splinter, WM1
Uozaki, Y1
Watanabe, G1
Kotou, K1
Ueyama, K1
Doi, Y1
Misaki, T1
Tanaka, N1
Sakahashi, H1
Sato, E1
Ishima, T1
Ishii, S1
Ellis, MH1
Santagostino, E1
Morfini, M1
Rocino, A1
Baudo, F1
Scaraggi, FA1
Gringeri, A1
Katz, E1
Gaitini, L1
Samri, M1
Egoz, N1
Nielsen, RE1
Ozal, E1
Kuralay, E1
Bingöl, H1
Cingöz, F1
Ceylan, S1
Tatar, H1
Sandrelli, L1
Speziali, G1
Grasso, MA1
Spagnolo, S1
Carson, S1
Ivanov, J1
Yu, R1
Tanaka, T1
Nakajima, N1
Yoshioka, A1
Fukui, H1
Miyauchi, Y1
Mii, Y1
Tamai, S1

Clinical Trials (179)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Tranexamic Acid in Debridement Surgery of Burns on the Volume of Bleeding in Transfusion Requirements at Centro Medico de Occidente'[NCT05855590]Phase 320 participants (Anticipated)Interventional2022-01-01Recruiting
PeriOperative ISchemic Evaluation-3 Trial[NCT03505723]Phase 39,535 participants (Actual)Interventional2018-06-27Completed
A Randomized, Parallel-group, Placebo Control, Non-inferiority Trial to Investigate the Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas Resection[NCT04595786]600 participants (Actual)Interventional2020-10-30Active, not recruiting
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial: Tranexamic Acid (TXA) Versus Placebo to Reduce Perioperative Blood Transfusion in Patients Undergoing Liver Resection: A Randomized Controlled Trial[NCT02261415]Phase 31,386 participants (Actual)Interventional2014-11-30Active, not recruiting
Disorders of the Acute Phase Response Accelerated by Plasmin Activation Following Trauma and Invasive Surgery: A Prospective Study[NCT03741023]320 participants (Anticipated)Interventional2019-12-12Enrolling by invitation
The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women: A Randomized Controlled Trial[NCT03820206]160 participants (Actual)Interventional2019-01-31Completed
Low Versus High Dose Tranexamic Acid in Adult Spinal Deformity Surgery: A Randomized, Blinded, Controlled Trial[NCT02053363]Phase 2/Phase 364 participants (Actual)Interventional2014-03-31Completed
Randomized Controlled Trial of Angiotensin 1-7 (TXA127) for the Treatment of Severe COVID-19[NCT04401423]Phase 222 participants (Actual)Interventional2021-02-10Completed
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC): A Pilot and Feasibility Study[NCT02840097]Phase 231 participants (Actual)Interventional2019-03-04Completed
Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass (the OPTIMAL Study)[NCT03782350]Phase 43,079 participants (Actual)Interventional2018-12-26Completed
Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery[NCT04754230]Phase 440 participants (Actual)Interventional2021-06-17Completed
Comparative Use of Tranexamic Acid Intravenous and Topical Application in the Treatment of Intertrochanteric Fractures With Proximate Femoral Nail[NCT04696224]90 participants (Anticipated)Interventional2020-12-18Recruiting
Efficacy of Tranexamic Acid in Femoral Shaft Fractures Osteosynthesis; A Double Blind Randomized Controlled Trial[NCT04803591]Phase 40 participants (Actual)Interventional2021-08-01Withdrawn (stopped due to Not approved by Ethics Commettee)
Use of Tranexamic Acid in Liposculpture: A Double-blind, Multicenter, Randomized Trial[NCT04430777]Phase 2/Phase 3141 participants (Actual)Interventional2019-01-17Completed
Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial[NCT05325671]120 participants (Anticipated)Interventional2022-04-05Not yet recruiting
TRACE STUDY: A Randomized Controlled Trial Using Tranexamic Acid in the Treatment of Subdural Hematoma[NCT05713630]Phase 3130 participants (Anticipated)Interventional2024-03-31Not yet recruiting
Tranexamic Acid in Major Vascular Surgery. A Randomized Placebo-controlled Trial.[NCT02335359]Phase 4100 participants (Actual)Interventional2015-03-04Completed
Extended Postoperative Tranexamic Acid Use in Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial[NCT05099276]Phase 446 participants (Actual)Interventional2021-12-07Active, not recruiting
Efficacy of Local Hemostatic Management in Implant Surgery in Anticoagulated Patients on Warfarin: a Randomized Clinical Study[NCT04846114]71 participants (Actual)Interventional2016-03-31Completed
Usage of Tranexamic Acid During Colonic Endoscopic Resection Procedures for Reduction Intraprocedural and Postprocedural Bleeding[NCT05345613]Phase 4200 participants (Anticipated)Interventional2022-05-01Recruiting
Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty - Randomized Prospective Study[NCT02152917]Phase 445 participants (Anticipated)Interventional2014-02-28Recruiting
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL[NCT03019198]Phase 4256 participants (Actual)Interventional2013-12-31Completed
Randomized Study on the Topical Application of Tranexamic Acid to Wound Bed for Hemostasis in the Setting Granulating Wounds Following Mohs Micrographic Surgery[NCT04541303]Early Phase 162 participants (Anticipated)Interventional2020-10-08Recruiting
Efficacy and Safety of Tranexamic Acid in Cytoreductive Surgery for Ovarian Cancer[NCT04360629]151 participants (Actual)Interventional2020-06-03Completed
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF[NCT05802238]Phase 2130 participants (Anticipated)Interventional2023-04-12Recruiting
TOPICAL AND INTRAVENOUS ADMINISTRATION OF TRANEXAMIC ACID ARE EQUALLY EFFECTIVE IN DIRECT ANTERIOR TOTAL HIP ARTHROPLASTY - A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL[NCT01940692]Phase 2120 participants (Actual)Interventional2014-07-31Completed
Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339]Phase 20 participants (Actual)Interventional2022-03-31Withdrawn (stopped due to Challenges in recruitment)
Effect of Intravenous Tranexamic Acid Plus Intramyometrial Desmopressin on Blood Loss During Laparoscopic Myomectomy: Randomized, Double-blind, Placebo-controlled Trial[NCT05517590]100 participants (Anticipated)Interventional2022-09-01Recruiting
The Efficacy and Population Pharmacokinetics/ Pharmacogenomics of a Reduced Dose of Tranexamic Acid for Craniosynostosis Surgery[NCT02188576]Phase 466 participants (Actual)Interventional2014-08-31Completed
Does Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Reduce Blood Loss and Transfusion Requirements? A Double-blinded Randomized Controlled Trial[NCT05024253]Phase 348 participants (Anticipated)Interventional2021-08-02Recruiting
Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage[NCT05554211]Phase 230 participants (Anticipated)Interventional2022-07-12Recruiting
Prospective, Multicenter, Randomized, Parallel Groups Study Comparing the Safety and the Efficacy of the Administration of One Intra-articular Injection of 4.8 ml (HO-1) or Three Intra-articular Injections of 2.2 ml (HS-3) of Pandora Gel to One Intra-arti[NCT05978180]252 participants (Anticipated)Interventional2023-10-18Recruiting
Prospective, Multicenter, Open Study Evaluating the Short-term Safety of Use of Pandora Administered in the Form of 1 Intra-articular Injection of Happyone or 3 Intra-articular Injections of Happysoft in Patients Suffering From Gonarthrosis[NCT05414617]20 participants (Actual)Interventional2022-06-08Completed
Is Serum Gentamicin Concentration Modified With Autologous Cell-saved Blood Transfusion After Total Knee Arthroplasty Using Tranexamic Acid: A Randomized Control Trial[NCT04505748]40 participants (Actual)Interventional2020-01-01Completed
Can the Prophylactic Administration of Tranexamic Acid Reduce Blood Loss After Robotic-assisted Radical Prostatectomy? The RARPEX (Robotic Assisted Radical Prostatectomy With TranEXamic Acid) Study.[NCT04319614]Phase 4200 participants (Actual)Interventional2020-02-24Completed
Tranexamic Acid's Effects in Patients Undergoing Laparoscopic Radical Prostatectomy: a Randomized, Double-blind, Placebo-controlled Trial[NCT05816668]Phase 3122 participants (Anticipated)Interventional2023-04-30Not yet recruiting
The Effect of Use of Tranexamic Acid in Percutaneous Nephrolithotomy on Blood Loss and Surgical Visual Clarity[NCT05947435]75 participants (Actual)Interventional2022-01-01Completed
Effects of the Application of a New Pharmacological Protocol for Shoulder Arthroscopy in Beach Chair Position[NCT05397652]Phase 4104 participants (Actual)Interventional2021-05-24Completed
HiFIT Study: Interest of Intravenous Iron and Tranexamic Acid to Reduce Transfusion in Hip Fracture Patients[NCT02972294]Phase 3419 participants (Actual)Interventional2017-03-31Terminated (stopped due to 1year inclusion hold due to PV new fact (Monofer hold for risk revaluation) DSMB Interim analysis : 1treatment with important transfusion risk reduction/inclusions issues (COVID)/sites change of practice if study continue=>stop inclusions)
Comparison of Topical Tranexamic Acid and Floseal® on Blood Loss After Total Knee Arthroplasty in Patients With a Thromboembolic Risk[NCT02865174]Phase 490 participants (Anticipated)Interventional2016-09-30Not yet recruiting
Impact of Tranexamic Acid Use in Transfusion Rate in Patients With Complex Kidney Stone Undergoing Percutaneous Nephrolithotomy: Randomised, Double-blind, Placebo Controlled Trial[NCT02966236]Phase 4192 participants (Anticipated)Interventional2016-06-30Recruiting
Comparison Between the Effect of Topical Tranexamic Acid Versus Hydrogen Peroxide on Perioperative Blood Loss in Elective Spine Surgeries[NCT05152186]Phase 3120 participants (Actual)Interventional2021-06-01Active, not recruiting
Topical Tranexamic Acid (TXA) in Hip Fractures, A Double-Blind, Randomized Controlled Trial[NCT02993341]Phase 365 participants (Actual)Interventional2016-11-30Completed
Use of TRanEXamic Acid in Reduction Mammoplasty (TREX-ARM): a Double-blinded Randomized Controlled Trial[NCT04947514]Phase 498 participants (Actual)Interventional2021-10-29Completed
The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery Based on Rotational Thromboelastometry (ROTEM®).[NCT03897621]50 participants (Actual)Interventional2019-05-20Completed
The Use of Tranexamic Acid in Chinese Elderly Patients Undergoing Femoral Nailing for Intertrochanteric Fracture: A Randomized Controlled Trial[NCT04290884]Phase 4120 participants (Anticipated)Interventional2018-05-23Active, not recruiting
Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid: a Clinical Trial[NCT03915756]42 participants (Anticipated)Interventional2019-08-22Recruiting
Tranexamic Acid in Knee Joint Surgery - a Randomised Controlled Trial[NCT02278263]Phase 4150 participants (Actual)Interventional2014-12-31Completed
The Effectiveness Of Intravenous Tranexamic Acid (TXA) on Reducing Perioperative Blood Loss For Patients Undergoing Periacetabular Osteotomy (PAO): A Randomized Double Blind Placebo Controlled Trial[NCT03823417]Phase 40 participants (Actual)Interventional2019-07-31Withdrawn (stopped due to Investigators decided not to begin the study.)
A Randomised, Prospective Evaluation on the Effectiveness of Tranexamic Acid in Reducing Postoperative Swelling and Haematoma Formation After the Latarjet Procedure.[NCT03458468]100 participants (Actual)Interventional2018-03-01Completed
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-blind and Randomized Controlled Trial[NCT04025736]72 participants (Actual)Interventional2017-06-07Completed
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
Role of Tranexamic Acid (TXA) in the Reduction of Post-operative Hematoma and Seroma in Patients Undergoing Panniculectomy or Abdominoplasty, a Pilot Study.[NCT04902950]Phase 49 participants (Actual)Interventional2020-08-17Terminated (stopped due to Logistics)
Comparative Study of the Efficiency of Oral Tranexamic Tcid vs. Oral Tminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement. A Prospective, Randomized, Double Blinded Controlled Clinical Trial.[NCT03365999]Phase 292 participants (Actual)Interventional2017-10-15Completed
The Effects of the Timing of Tranexamic Acid Administration on Blood Loss in Hip Fractures.[NCT04488367]Early Phase 1120 participants (Anticipated)Interventional2020-07-06Recruiting
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss, Transfusion Index and Complications After Total Hip Replacement. A Prospective, Randomized, Double Blind Clinical Trial[NCT04187014]Phase 290 participants (Actual)Interventional2020-02-06Completed
Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy[NCT03954860]80 participants (Actual)Interventional2018-08-01Completed
Blood-saving Effect of Kaolin-based Hemostatic Gauze Combined With Intravenous Tranexamic Acid in Total Knee Arthroplasty[NCT05504577]Phase 4120 participants (Anticipated)Interventional2022-03-16Recruiting
Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Caesarean Delivery: a Multicenter Randomized Double Blind Placebo Controlled Therapeutic and Pharmaco-biological Dose Ranging Study (TRACES) for Its Optimal Benefit/Risk[NCT02797119]Phase 4225 participants (Actual)Interventional2016-03-15Terminated (stopped due to Study will be stopped due to the impossibility of reaching the objective of inclusions within a reasonable time frame and taking into account the recommendations of the international WOMAN study)
Use of Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery[NCT03856164]Phase 2/Phase 3110 participants (Actual)Interventional2019-06-17Completed
Evaluation of Tranexamic Acid Prior to Surgery in the Geriatric Hip Fracture Population for the Reduction of Post-Operative Blood Transfusion[NCT03923959]Phase 3400 participants (Anticipated)Interventional2020-02-01Active, not recruiting
Tranexamic Acid During Cystectomy Trial (TACT)[NCT01869413]Phase 2/Phase 3354 participants (Actual)Interventional2013-06-30Completed
Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events[NCT05313620]Phase 430 participants (Anticipated)Interventional2022-04-01Recruiting
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis[NCT05774717]Phase 160 participants (Anticipated)Interventional2023-04-01Recruiting
Efficacy of Tranexamic Acid in Reducing Requirement of Blood Transfusion in Lower Limb Trauma Surgery: A Prospective Randomized Controlled Study[NCT04986813]Phase 4100 participants (Actual)Interventional2017-04-01Completed
Study of the Noninferiority of an Oral vs Intravenous Administration of Tranexamic Acid in Total Hip Arthroplasty[NCT04691362]Phase 4230 participants (Actual)Interventional2021-01-01Completed
Local Injection of Tranexamic Acid May Reduce Bleeding, Injection Pain, and Other Post-op Complications During Mohs Micrographic Surgery[NCT04630886]Early Phase 1200 participants (Anticipated)Interventional2021-06-16Enrolling by invitation
Intravenous Versus Topical Use of Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries (TARGETS) : A Prospective, Randomized, Double Blind, Head-to-head Comparison Study[NCT03011866]176 participants (Anticipated)Interventional2017-02-28Not yet recruiting
Topical Application Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery[NCT05708690]Phase 4132 participants (Actual)Interventional2022-10-01Completed
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) Study[NCT03954314]Phase 33,242 participants (Actual)Interventional2019-09-17Terminated (stopped due to Upon the Data Safety Monitoring Board review of the interim analysis (75% of participants have finished their follow-up) on November 17, 2023, they made a recommendation to stop recruitment into the trial.)
Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project[NCT04559880]Phase 425 participants (Actual)Interventional2020-09-10Active, not recruiting
Effects of Antifibrinolytics on Bleeding and Transfusion Outcomes in Patients Receiving Coronary Artery Bypass Surgery With Preoperative Clopidogrel Exposure[NCT01060163]552 participants (Actual)Interventional2010-01-31Completed
Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage: A Randomized, Double-blinded, Placebo-controlled Pilot Trial[NCT03069859]Phase 231 participants (Actual)Interventional2018-03-06Active, not recruiting
Pilot RCT: Use of Tranexamic Acid (TXA) in Post Mastectomy Patients for Seroma and Hematoma Prevention[NCT03738527]Phase 4100 participants (Anticipated)Interventional2019-10-07Recruiting
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty[NCT03825939]Phase 452 participants (Actual)Interventional2015-04-21Terminated (stopped due to Lack of patient enrollment due to only one surgeon that was enrolling.)
Comparison of Combined Topical Tranexamic Acid With Floseal® With Intravenous Tranexamic Acid on Blood Loss in Total Knee Arthroplasty[NCT03328832]Phase 470 participants (Actual)Interventional2017-09-12Completed
Blood Loss Reduction After Total Knee Arthroplasty. A Comparison Between Topical Tranexamic Acid and Platelet Rich Plasma: Controlled Clinical Trial[NCT02650856]Phase 340 participants (Actual)Interventional2015-09-30Completed
A Randomized Control Trial Evaluating the Use of Topical Tranexamic Acid in Bilateral Breast Reduction Surgery to Prevent Bleeding Complications[NCT04918576]Phase 3106 participants (Anticipated)Interventional2022-08-31Not yet recruiting
Effects of Tranexamic Acid for Alloplastic Breast Reconstruction: A Randomized Control Trial[NCT04918589]Phase 3106 participants (Anticipated)Interventional2022-08-31Not yet recruiting
Comparison of Topical and Infusion Tranexamic Acid on Blood Loss and Risk of Deep Vein Thrombosis After Total Knee Arthroplasty[NCT02453802]Phase 490 participants (Anticipated)Interventional2015-06-30Not yet recruiting
Single Centre Randomised Controlled Trial to Assess the Effect of the Addition of Twenty-four Hours of Oral Tranexamic Acid Post-operatively to a Single Intra-operative Intravenous Dose of Tranexamic Acid on Calculated Blood Loss Following Primary Hip and[NCT03690037]Phase 41,089 participants (Actual)Interventional2016-07-07Completed
Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta Study (TAPPAS): A Randomized, Placebo-controlled Double Blind Trial[NCT02806024]Phase 414 participants (Actual)Interventional2016-11-30Completed
The Use of Tranexamic Acid in Irrigation Fluid to Improve Arthroscopic Visualization in Shoulder Surgery: A Randomized Controlled Trial[NCT04594408]Phase 4128 participants (Actual)Interventional2020-09-01Active, not recruiting
Range of Motion and Function Following Primary Repair of Traumatic Zone 1 or Zone 2 Digit Flexor Tendon Injuries - Impact of Tranexamic Acid Use - A Prospective Study[NCT04178655]Early Phase 148 participants (Anticipated)Interventional2019-11-30Not yet recruiting
Investigation of the Blood Sparing Properties of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty[NCT02569658]110 participants (Actual)Interventional2015-09-30Completed
Evaluation of the Pharmacokinetic Profile of Tranexamic Acid, After Injection in a Knee Neo-articulation.[NCT02319915]Early Phase 114 participants (Actual)Interventional2015-02-18Completed
Evaluation of the Minimum Concentration of Tranexamic Acid Required to Inhibit Fibrinolysis in a Population of Pregnant Women at Term.[NCT02579941]40 participants (Actual)Interventional2015-11-30Completed
Prophylactic Use of Topical Tranexamic Acid to Aid Surgical Haemostasis During Caesarean Sections in Parturients With Moderate to High Risk of Bleeding[NCT02492087]Phase 384 participants (Anticipated)Interventional2015-08-31Recruiting
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty: A Prospective, Double-Blind Randomized, Controlled Trial[NCT03074994]Phase 2108 participants (Anticipated)Interventional2016-10-31Recruiting
[NCT02644473]Phase 40 participants (Actual)Interventional2016-02-29Withdrawn (stopped due to Study did not receive IRB approval, so did not start)
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean Delivery: A Randomized Controlled Trial[NCT03364491]Phase 311,000 participants (Actual)Interventional2018-03-15Completed
Comparative Study For Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section: A Randomised Controlled Trial[NCT02739815]Phase 4200 participants (Actual)Interventional2016-04-30Completed
Tranexamic Acid Versus Novel Uterine Cooling Technique in Reducing Blood Loss and Incidence of Postpartum Hemorrhage at Caesarean Section[NCT02780245]Phase 4100 participants (Actual)Interventional2016-06-30Completed
Precise Application of Topical Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding: A Randomized Controlled Study[NCT05248321]60 participants (Actual)Interventional2022-03-24Completed
A Multi-centre Randomised, Double-blinded, Placebo-controlled Trial of Pre-hospital Treatment With Tranexamic Acid for Severely Injured Patients at Risk of Acute Traumatic Coagulopathy.[NCT02187120]Phase 31,310 participants (Actual)Interventional2014-07-28Completed
The Effect of Intravenous E-Aminocaproic Acid (EACA) on Blood Loss and Transfusion Requirements After Bilateral Varus Rotational Osteotomy (VRO)[NCT02257580]Phase 428 participants (Actual)Interventional2015-04-01Completed
Tranexamic Acid Comparison in Hip Replacement (TeACH-R) Trial: Comparative Efficacy of Intravenous Versus Topical Tranexamic Acid for Reducing Blood Loss in Elective Primary Total Hip Arthroplasty.[NCT02056444]149 participants (Actual)Interventional2014-02-28Completed
Tranexamic Acid (TXA) During Pediatric Cardiac Surgery: A Prospective Randomised Study Comparing Two Dosing Regimens[NCT01141127]Phase 218 participants (Actual)Interventional2010-06-30Completed
IV Tranexamic Acid Prior to Hysterectomy for Reduction of Intraoperative Blood Loss: A Randomized Placebo-Controlled Trial[NCT02911831]Early Phase 171 participants (Actual)Interventional2016-11-30Completed
Blood Transfusion Applications in Hip Replacements: A Retrospective Study[NCT05627544]560 participants (Actual)Observational2022-11-01Completed
The Impact of Topical Tranexamic Acid on Pre- and Post-operative Hemoglobin / Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: a Prospective, Randomized, Double-blinded, Multicenter Study[NCT05357079]Early Phase 198 participants (Anticipated)Interventional2017-08-25Recruiting
A Novel Technique Of Uterine Cooling During Repeated Cesarean Section For Reducing Blood Loss[NCT03793153]99 participants (Actual)Interventional2018-12-19Completed
The Use of Tranexamic Acid to Reduce the Need for Transfusion 1 Week Post-operatively for Hemiarthroplasty or Intramedullary Nailing Needed to Correct Acute Hip Fractures[NCT02947529]Phase 4113 participants (Actual)Interventional2015-08-31Completed
Prospective Randomized Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty[NCT03359525]Phase 4114 participants (Anticipated)Interventional2017-07-01Recruiting
The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816]25 participants (Actual)Interventional2016-04-30Terminated (stopped due to Study enrollment and goals unable to be reached.)
Serial Use of Intravenous and Oral Tranexamic Acid in Primary Total Knee Arthroplasty Patients: A Randomized Controlled Study[NCT03109652]Phase 4144 participants (Anticipated)Interventional2017-07-10Recruiting
Evaluation of the Use of Tranexamic Acid in Tibial Osteotomies: a Randomised Controlled Clinical Trial.[NCT04785651]84 participants (Anticipated)Interventional2021-02-22Recruiting
Efficacy of Topical Tranexamic Acid Versus Intravenous Administration to Reduce Blood Transfusion Rate in Total Knee Arthroplasty Surgery: Phase III, Unicentric, Controlled,Double Blind, Randomized Non Inferiority Clinical Trial.[NCT01881568]Phase 379 participants (Actual)Interventional2013-01-31Completed
By Reza Abbasi and Isfahan University of Medical Sciences[NCT02493894]Phase 1/Phase 2105 participants (Actual)Interventional2014-07-31Completed
Topical Intranasal Tranexamic Acid for Epistaxis in the Emergency Department[NCT02930941]Phase 435 participants (Actual)Interventional2016-02-29Terminated (stopped due to Terminate due to slow enrollment rate.)
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application, a Comparison With Intravenous Tranexamic Acid Only in Total Hip Arthroplasty[NCT03623789]Phase 490 participants (Anticipated)Interventional2018-08-15Recruiting
Prevention of Postpartum Hemorrhage With Tranexamic Acid (TXA)[NCT03326596]Phase 41,000 participants (Anticipated)Interventional2018-04-20Recruiting
Analgesic Efficacy of Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA): A Prospective Randomized Trial to Compare Postoperative Clinical Outcomes[NCT02908711]Phase 450 participants (Actual)Interventional2016-10-31Completed
Analgesic Efficacy of Quadaratus Lumborum Block (QLB) for Laparoscopic Colectomy Surgery: A Prospective Observational Case Control Trial to Evaluate Clinical Outcomes[NCT03017638]14 participants (Actual)Observational2017-02-27Completed
Peri-articular Tranexamic Acid Injection in Total Knee Arthroplasty: A Randomized Controlled Trial[NCT02829346]Phase 260 participants (Actual)Interventional2012-10-31Completed
Comparison of the Effect of Two Common Regimens of Administration of Tranexamic Acid on Hemostasis and Clinical Outcome of Patients Undergoing Total Knee Arthroplasty[NCT04443920]Phase 486 participants (Actual)Interventional2019-10-29Completed
An Ideal End-tidal Carbon Dioxide Level to Control Intraoperative Bleeding and Improve the Quality of Surgical Field Vision in Septorhinoplasty Operations Under General Anesthesia: a Prospective Clinical Study[NCT05497375]70 participants (Actual)Interventional2022-08-20Completed
The Effect of Intraoperative Low Dose Adrenaline on Bleeding in Total Hip Arthroplasty - a Randomized Placebo-controlled Trial[NCT01708642]Phase 3106 participants (Actual)Interventional2012-11-30Completed
Does Tranexamic Acid Significantly Reduce Total Blood Loss During Proximal Femoral Nailing for the Intertrochanteric Femoral Fracture in the Elderly?[NCT05359172]100 participants (Actual)Observational2021-04-01Completed
Evaluation of Efficacy and Safety of Perioperative Tranexamic Acid During Primary Total Knee Arthroplasty: A Randomized, Clinical Trial[NCT05919615]100 participants (Actual)Interventional2021-07-15Completed
Do Peri-operative High Doses of Intravenous Glucocorticoids Improve Short-term Functional Outcome After Direct Anterior Total Hip Arthroplasty? A Randomized, Single Surgeon, Placebo Controlled, Double Blind Study[NCT04317872]70 participants (Anticipated)Interventional2020-07-01Recruiting
The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures: A Prospective, Double-Blind, Randomized Controlled Trial[NCT01940536]Phase 40 participants (Actual)Interventional2015-12-31Withdrawn (stopped due to Possible change in study protocol)
Open Label, Non-Randomized, Study to Evaluate the Pharmacokinetics of Tranexamic Acid in Patients Undergoing Major Liver Resection[NCT01651182]Phase 324 participants (Actual)Interventional2014-03-31Completed
Randomized Control Trial Investigating for Prophylactic Tranexamic Acid Use at Time of Minimally Invasive Myomectomies[NCT04311073]Phase 350 participants (Anticipated)Interventional2020-06-20Recruiting
Multicenter, Randomized Placebo-controlled Clinical Trial to Evaluate the Effect of Perioperative Use of Tranexamic Acid on Transfusion Requirements and Surgical Bleeding in Major Spine Surgery[NCT01136590]Phase 496 participants (Actual)Interventional2010-09-30Completed
The Effect of Magnesium Sulphate on Intraoperative Blood Loss in Meningioma Patient Undergoing Craniotomy With Tumor Removal[NCT03558516]Phase 380 participants (Actual)Interventional2018-08-01Completed
The Influence of High-Dose Aprotinin and Tranexamic Acid on Bleeding Tendency and Allogeneic Blood Transfusion in Patients Undergoing Primary Aortic Valve Replacement or Coronary Artery Revascularization[NCT00396760]Phase 3220 participants Interventional2005-01-31Active, not recruiting
Topical Application of Tranexamic Acid to Reduce Postoperative Blood Loss in Posterior Approach Spinal Surgery[NCT02063035]Phase 429 participants (Actual)Interventional2012-08-31Completed
The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery[NCT01728636]Phase 261 participants (Actual)Interventional2013-01-15Completed
Role of Topical Tranexamic Acid in Total Hip Arthroplasty[NCT01866943]Phase 241 participants (Actual)Interventional2011-11-30Terminated
Role of Tranexamic Acid for Reducing Blood Loss in Patients Undergoing Major Gastro-intestinal Surgery[NCT01655641]Phase 2/Phase 3118 participants (Anticipated)Interventional2012-07-31Active, not recruiting
The PRICE Trial: Phlebotomy Resulting in Controlled Hypovolemia to Prevent Blood Loss in Major Hepatic Resections[NCT02548910]62 participants (Actual)Interventional2016-04-30Completed
Exploratory Phase IV Randomized Single Blind Study Evaluating the Efficacy and Tolerability of Hemopatch in Improving Time of Hemostasis and Preventing Post-operative Complications After Hepatic Resection[NCT03323359]98 participants (Anticipated)Interventional2017-03-17Recruiting
PRICE 2: A Phase 3 Randomized Controlled Trial of Phlebotomy Resulting in Controlled Hypovolemia to Prevent Blood Loss in Major Hepatic Resections[NCT03651154]440 participants (Anticipated)Interventional2018-09-28Active, not recruiting
Topical Application of Tranexamic Acid to Reduce Post-operative Bleeding in Coronary Artery Bypass Surgery[NCT01519245]Phase 344 participants (Actual)Interventional2011-12-31Completed
Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599]40 participants (Actual)Interventional2011-01-31Completed
The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery[NCT02684851]Phase 387 participants (Actual)Interventional2012-10-31Completed
Efficacy of Tranexamic Acid on Perioperative Blood Loss During Hip Fracture Surgery.[NCT00327106]Phase 3110 participants (Actual)Interventional2005-04-30Completed
Evaluation of the Safety and Efficacy of the Second Dose of Tranexamic Acid Administration of Trauma Patients: A Randomized, Double-blind Controlled Clinical Trial[NCT03846973]Phase 3220 participants (Actual)Interventional2018-12-02Completed
The Effect of Preoperative Tranexamic Acid on Blood Loss and Transfusion Rates in Intertrochanteric and Subtrochanteric Femur Fractures.[NCT02580227]Phase 4100 participants (Anticipated)Interventional2015-06-30Recruiting
Use of Combined Tranexamic Acid and Intravenous Iron for Hip Fracture Surgery in Elderly[NCT02428868]150 participants (Anticipated)Interventional2015-04-30Not yet recruiting
Seizures After Cardiac Surgery -- A Prospective Study With Continuous EEG Monitoring[NCT01291992]100 participants (Actual)Observational2010-09-30Completed
Single Dose Tranexamic Acid for Dacryocystorhinostomy[NCT01221909]80 participants (Anticipated)Interventional2010-12-31Not yet recruiting
Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty, a Randomized-clinical Trial.[NCT01651806]Phase 2/Phase 365 participants (Actual)Interventional2012-05-31Completed
Indication and Treatment of Adult Kyphoscoliosis[NCT04536909]300 participants (Anticipated)Observational [Patient Registry]2020-01-01Recruiting
A Prospective, Randomized, Double-blinded Single-site Control Study Comparing Blood Loss Prevention of Tranexamic Acid (TXA) to Epsilon Aminocaproic Acid (EACA) for Corrective Spinal Surgery[NCT00958581]Phase 4177 participants (Actual)Interventional2008-12-31Completed
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement; A Prospective Triple-blinded Randomized Controlled Trial.[NCT01850394]152 participants (Actual)Interventional2010-01-31Completed
The Blood Saving Effect and Wound-related Complications of Tranexamic Acid in Mininally Invasive Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis[NCT02458729]Phase 4294 participants (Actual)Interventional2012-08-31Completed
Tranexamic Acid for Preventing Postpartum Haemorrhage Following a Vaginal Delivery: a Multicenter Randomised Double Blind Placebo Controlled Trial[NCT02302456]Phase 34,079 participants (Actual)Interventional2015-02-28Completed
The Efficacy of Intravenous Tranexamic Acid in Decreasing Blood Loss in Pediatric Idiopathic Scoliosis Surgery?[NCT01813058]Phase 1/Phase 2120 participants (Actual)Interventional2013-01-31Completed
Peroperative Tranexamic Acid as Prophylaxis of Haemorrhage in Benign Hysterectomy - a Randomized, Placebo-controlled Trial[NCT01940419]Phase 4332 participants (Actual)Interventional2013-04-30Completed
Efficacy of ε-Aminocaproic Acid (EACA) in Children Undergoing Craniofacial Reconstruction Surgery[NCT02229968]Phase 222 participants (Actual)Interventional2014-10-31Active, not recruiting
CONSERV - 2 (Clinical Outcomes and Safety Trial to Investigate Ecallantide's Effect on Reducing Surgical Blood Loss Volume) - A Phase 2 Randomized Double-Blind Active-Controlled Study in Subjects Exposed to Cardio-pulmonary Bypass During Cardiac Surgery a[NCT00888940]Phase 2243 participants (Actual)Interventional2009-06-30Completed
Prospective Randomised Trial Comparing Intraoperative Topical Quixil and Intravenous Tranexamic Acid, in Reduction of Blood Loss Following Primary Hip & Knee Joint Replacement Surgery.[NCT00378872]132 participants (Actual)Interventional2006-06-30Completed
Tranexamic Acid Reduces Blood Loss in Pediatric Cardiac Surgery[NCT00994994]160 participants (Actual)Interventional2006-01-31Completed
The Effect of Tranexamic Acid on Blood Loss and Transfusion Rates in Major Oncologic Surgery[NCT01980355]76 participants (Actual)Interventional2012-06-12Completed
Efficacy of Tranexamic Acid in Reducing Perioperative Bleeding in Patients Undergoing Radical Prostatectomy. A Randomized Controlled Double-blind Study.[NCT00670345]Phase 40 participants Interventional2008-04-30Completed
Intravenous Tranexamic Acid to Reduce Blood Loss in Reverse Total Shoulder Arthroplasty[NCT02043132]Phase 2/Phase 3116 participants (Actual)Interventional2013-09-30Completed
Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis Using an in Vitro Experimental Model of Fibrinolysis.[NCT02352675]40 participants (Actual)Observational2015-04-30Completed
A Randomized Comparison of Two Doses of Tranexamic Acid in Open-Heart Surgery[NCT04996368]120 participants (Actual)Interventional2022-02-01Completed
The Effect of Tranexamic Acid (TXA) on Blood Loss in Burn Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT03113253]Phase 4121 participants (Actual)Interventional2016-09-22Active, not recruiting
The Combined Efficacy of Evicel and Tranexamic Acid on Total Knee Arthroplasty During the Early Perioperative Period[NCT02553122]Phase 30 participants (Actual)Interventional2015-10-31Withdrawn (stopped due to Data has been published on this study (this would have been a duplicate study))
Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103]30 participants (Actual)Interventional2018-02-02Completed
Use of Tranexamic Acid for Bleeding Reduction in Adenotonsillectomy in Children[NCT01228136]Phase 495 participants (Actual)Interventional2010-01-31Completed
Temporary Clamping of Drains Combined With Tranexamic Acid Reduce Blood Loss After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.[NCT01449552]240 participants (Actual)Interventional2008-06-30Completed
The Effect on Blood Loss of Topical and Intravenous Tranexamic Acid in Cardiac Surgery Patients: a Randomized Placebo-controlled Trial[NCT01895101]Phase 4750 participants (Actual)Interventional2013-10-31Completed
Efficacy and Safety of Erythropoietin And/Or Intravenous Iron Sucrose For Treatment of Anemia In Hip and Knee Arthroplasty: A Single-center Retrospective Study[NCT03917394]780 participants (Anticipated)Observational2019-04-24Recruiting
Prevention of Bleeding and Edema in Bimaxillary Orthognathic Surgery; the Effectiveness of Tranexamic Acid on Intraoperative Bleeding and Postoperative Swelling in Orthognathic Surgery.[NCT02229292]Phase 4104 participants (Actual)Interventional2014-08-19Completed
Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery: A Double Blind Randomized Controlled Trial[NCT01111669]28 participants (Actual)Interventional2009-08-31Completed
Randomized Placebo Controlled Study Using Tranexamic Acid in Revision Total Hip Arthroplasty[NCT00375440]0 participants (Actual)Interventional2005-02-28Withdrawn (stopped due to Study halted prematurely as investigator left the institution.)
Tranexamic Acid in Surgery of Advanced Ovarian Cancer - a Prospective Randomized Double Blind Placebo Controlled Study[NCT00740116]Phase 4100 participants (Actual)Interventional2008-03-31Completed
A Prospective, Randomized, Single-blinded, Non-inferiority Study to Evaluate the Safety and Efficacy of the Saline-coupled Bipolar Sealer Compared to the Unipolar Electrocautery in Primary Unilateral Total Knee Arthroplasty[NCT03952546]211 participants (Actual)Interventional2019-05-07Completed
Tranexamic Acid for the Reduction of Allogeneic Blood Exposure in Infants and Children Having Craniofacial Surgery[NCT00722436]Phase 420 participants (Actual)Interventional2008-07-31Terminated (stopped due to Study dose changed based on recent publications)
Influence of Elevated Baseline Serum Creatinine and Body Composition on Acute Kidney Injury in Cardiac Surgery - The InCreAS Trial[NCT02598271]200 participants (Actual)Observational2016-10-31Completed
Early Versus Late Post Caesarean Section Oral Anticoagulation Initiation and Risk of Maternal Complications in Patients With Mechanical Heart Valve Prosthesis[NCT04855110]114 participants (Anticipated)Interventional2021-04-19Recruiting
Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery[NCT04058665]300 participants (Actual)Observational2019-06-18Completed
The Effect of Tranexamic Acid on Intraoperative and Post-Operative Bleeding in Functional Endoscopic Sinus Surgery: A Randomized, Prospective, Double-Blinded Study[NCT00671281]74 participants (Anticipated)Interventional2008-10-31Withdrawn (stopped due to Study was cancelled)
Efficacy of Tranexamic Acid in Reducing Blood Loss During and After Caesarean Section[NCT02350179]Phase 1/Phase 2100 participants (Anticipated)Interventional2014-06-30Recruiting
The Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty[NCT01815918]Phase 460 participants (Actual)Interventional2011-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood Loss

"To compare the estimated blood loss in patients undergoing complex, reconstructive, spinal fusion surgeries receiving one of two dosing protocols for the anti-fibrinolytic, TXA.~Estimated blood loss was calculated by suction canister volume minus intraoperative irrigation fluid plus blood content in sponges as estimated by weight for all cases." (NCT02053363)
Timeframe: This outcome is measured during surgery, from exposure to wound closure, approximately 8 hours.

InterventionmL (Mean)
High Dose/Study Group2046
Standard of Care/Control1596

Number of Patients Sustaining Intraoperative or 90 Day Complications

To compare the rates of intraoperative complications and 90 day complications observed in the two groups. (NCT02053363)
Timeframe: Perioperative complications were defined as complications occurring within 90 days of surgery.

InterventionParticipants (Count of Participants)
High Dose/Study Group2
Standard of Care/Control3

Red Blood Cell Transfusions

To compare the mean volume (mL) of packed red blood cell (PRBC) transfusions given to the two groups. Volumes of RBC vary from bag to bag and real volumes will be recorded as provided by the blood bank. (NCT02053363)
Timeframe: Participants will be followed for the duration of their hospital stay measured from day of surgery to day of discharge from the hospital, approximately 7 days.

InterventionmL (Mean)
High Dose/Study Group1259
Standard of Care/Control935

Change of Serum Creatinine

Calculated from baseline (at enrollment) to end of study (NCT04401423)
Timeframe: Day 1 and Day 10

Interventionmg/dL (Mean)
TXA1270.92
Placebo0.70

Mortality

(NCT04401423)
Timeframe: Day 1 to Day 10

InterventionParticipants (Count of Participants)
TXA1271
Placebo0

Number of Participants Requiring a Vasopressors

(NCT04401423)
Timeframe: Up to Day 10

InterventionParticipants (Count of Participants)
TXA1273
Placebo1

Number of Participants Requiring Dialysis

(NCT04401423)
Timeframe: Up to Day 10

InterventionParticipants (Count of Participants)
TXA1270
Placebo0

Number of Participants Requiring Intubation

(NCT04401423)
Timeframe: From Day 1 to Day 10

InterventionParticipants (Count of Participants)
TXA1273
Placebo2

Percent Change in Supplemental Oxygen Requirements

(NCT04401423)
Timeframe: Day 1 and Day 10

Interventionpercent change of oxygen (Mean)
TXA1270.71
Placebo0.91

Cytokine Levels on the Day 5 of Drug/TXA Administration

(NCT04401423)
Timeframe: Day 5

,
Interventionpg/ml (Median)
Interferon-γIL-1βIL-1RaIL-2IL-4IL-5IL-6IL-8TNF-αIL-10IL-12p40IL-12p70IL-13MCP-1
Placebo0.7850.67.380.910.740.991.3414.342.14.1929.81.2111.4237
TXA1270.8814.417.770.200.093.3612.8824.531.12.4645.401.2810.71218

Cytokine Levels on the Day of Drug/TXA Administration

(NCT04401423)
Timeframe: Day 1

,
Interventionpg/ml (Median)
Interferon-γIL-1βIL-1RaIL-2IL-4IL-5IL-6IL-8TNF-αIL-10IL-12p40IL-12p70IL-13MCP-1
Placebo1.030.67.60.370.211.213.3516.245.910.828.90.638.5283
TXA1271.4420.715.90.520.411.729.6324.468.412.332.41.749.9345

Days of Hospital Stay and Drug Administration

(NCT04401423)
Timeframe: Day 1 to Day 10

,
Interventiondays (Median)
Length of Hospital StayDays of Drug/placebo administration
Placebo75
TXA127114

Blood Transfusion

Total volume of packed red blood cells, platelets, fresh frozen plasma, and cryoprecipitate (NCT02840097)
Timeframe: First 48 hours after randomization

Interventionml (Mean)
Tranexamic Acid Dose A367.4
Tranexamic Acid Dose B150.4
Placebo303.6

Intracranial Hemorrhage Progression

Intracranial hemorrhage progression on cranial computed tomography (CT) imaging; hemorrhage will be measured using the ABC/2 volume estimation and relative to the total brain volume (calculated by the XYZ/2 volume estimation); more intracranial hemorrhage progression represents a worse outcome. Change is calculated as the difference between the baseline and repeat cranial CT imaging. The repeat CT is conducted 24 hours (±6 hours) after the baseline CT. (NCT02840097)
Timeframe: 24 hours (±6 hours)

InterventionProportional change (Mean)
Tranexamic Acid Dose A0.003
Tranexamic Acid Dose B0.001
Placebo0.003

Number of Participants With Any Non-cerebral Venous or Arterial Thrombosis

Any non-cerebral venous or arterial thrombosis on standard diagnostic imaging post-randomization (NCT02840097)
Timeframe: Day 7 of hospitalization or hospital discharge (whichever comes first)

InterventionParticipants (Count of Participants)
Tranexamic Acid Dose A0
Tranexamic Acid Dose B0
Placebo0

Number of Participants With Seizures

Clinical or electroencephalogram-documented (NCT02840097)
Timeframe: 24 hours after receiving drug

InterventionParticipants (Count of Participants)
Tranexamic Acid Dose A0
Tranexamic Acid Dose B0
Placebo1

Pediatric Quality of Life Inventory (PedsQL)

Neurocognitive functioning and quality-of-life measures; range from 0 to 100 quality of life units with higher scores representing better outcomes. Measurements occur at 1 week, 1 month, 3 months, and 6 months to generate an area under the curve of quality of life units. (NCT02840097)
Timeframe: 6 months

InterventionQuality of life units * months (Mean)
Tranexamic Acid Dose A64.9
Tranexamic Acid Dose B60.2
Placebo67.2

Digit Span Recall Test

Test of working memory; higher scores represent a better outcome, range from 0 to infinity (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionscore on a scale (Mean)
Total forward digit span, 1 weekTotal backward digit span, 1 weekTotal forward digit span, 1 monthTotal backward digit span, 1 monthTotal forward digit span, 3 monthsTotal backward digit span, 3 monthsTotal forward digit span, 6 monthsTotal backward digit span, 6 months
Placebo8.87.37.55.38.66.58.45.8
Tranexamic Acid Dose A8.46.07.26.29.18.711.710.4
Tranexamic Acid Dose B8.46.07.96.210.47.810.06.0

Glasgow Outcome Scale-Extended (GOS-E) Peds

Global functioning; range is 1 to 8 with higher scores representing better outcomes; 1=death, 2=vegetative state, 3=lower severe disability, 4=upper severe disability, 5=lower moderate disability, 6=upper moderate disability, 7=lower good recovery, 8=upper good recovery (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionscore on a scale (Mean)
1 week1 month3 months6 months
Placebo5.34.54.24.3
Tranexamic Acid Dose A4.64.93.83.7
Tranexamic Acid Dose B5.25.14.62.9

Pediatric Quality of Life Inventory (PedsQL)

Neurocognitive functioning and quality-of-life measures; range from 0 to 100 with higher scores representing better outcomes (NCT02840097)
Timeframe: 1 week, 1 month, 3 months, and 6 months

,,
Interventionunits on a scale (Mean)
1 week1 month3 months6 months
Placebo57.960.568.968.9
Tranexamic Acid Dose A43.757.077.381.6
Tranexamic Acid Dose B52.461.577.584.3

Bleeding VAS - POD1

Patient-reported Visual Analog Scale - Bleeding Score Day 1. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 1 (assessed within first 24 hours following surgery)

Interventionscore on a scale (Mean)
Normal Saline5.03
1,000mg IV Tranexamic Acid4.82

Bleeding VAS - POD2

Patient-reported Visual Analog Scale - Bleeding Score Day 2. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 2

Interventionscore on a scale (Mean)
Normal Saline4.47
1,000mg IV Tranexamic Acid3.89

Bleeding VAS - POD3

Patient-reported Visual Analog Scale - Bleeding Score Day 3. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 3

Interventionscore on a scale (Mean)
Normal Saline2.93
1,000mg IV Tranexamic Acid2.29

Bleeding VAS - POD4

Patient-reported Visual Analog Scale - Bleeding Score Day 4. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 4

Interventionscore on a scale (Mean)
Normal Saline2.12
1,000mg IV Tranexamic Acid1.44

Bleeding VAS - POD5

Patient-reported Visual Analog Scale - Bleeding Score Day 5. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 5

Interventionscore on a scale (Mean)
Normal Saline1.32
1,000mg IV Tranexamic Acid1.15

Bleeding VAS - POD6

Patient-reported Visual Analog Scale - Bleeding Score Day 6. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 6

Interventionscore on a scale (Mean)
Normal Saline1.36
1,000mg IV Tranexamic Acid0.76

Bleeding VAS - POD7

Patient-reported Visual Analog Scale - Bleeding Score Day 7. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 7

Interventionscore on a scale (Mean)
Normal Saline0.97
1,000mg IV Tranexamic Acid0.72

Frequency of Participant Follow-up

Number of patients in each arm requiring evaluation by the resident service for bleeding concerns expressed by the recovery nurse (in PACU), had any follow-up visit or phone call outside of regularly scheduled follow-up (NCT04754230)
Timeframe: Day of surgery through 1 week

,
InterventionParticipants (Count of Participants)
PACUFollow-up visitFollow-up phone call
1,000mg IV Tranexamic Acid012
Normal Saline002

Guaze Saturation VAS Though POD7

Patient-reported Visual Analog Scale - Guaze Saturation Score through Postoperative Day 7. Score range: 0 (not at all) to 10 (dripping blood). (NCT04754230)
Timeframe: Postoperative Day 2 through Postoperative Day 7

,
Interventionscore on a scale (Mean)
Postoperative day 2Postoperative day 3Postoperative day 4Postoperative day 5Postoperative day 6Postoperative day 7
1,000mg IV Tranexamic Acid4.562.090.760.400.290.28
Normal Saline5.163.031.741.110.990.80

Efficacy of TXA in Childrens Having Craniosynostosis Surgery

Determine the efficacy ( as measured by blood loss and blood transfusion) of TXA in infants and children undergoing open craniofacial surgery with this lower dosage scheme. (NCT02188576)
Timeframe: perioperatively from the intraoperative period to 24 hours postoperatively

InterventionmL/kg (Mean)
High Dose TXA23.6
Low Dose TXA21.3

Plasma Levels of TXA in Children Having Craniosynostosis Surgery

Determine the plasma levels (in micrograms/mL) of TXA in infants and children undergoing open craniofacial surgery with this dosage scheme (NCT02188576)
Timeframe: up to 24h postoperatively

Interventionug/mL (Mean)
High Dose TXA50.2
Low Dose TXA29.6

Number of Breasts With Development of Hematoma

The number of breasts with clinically significant hematoma (collection of blood under the skin) requiring either conservative management or operative washout was determined. (NCT04947514)
Timeframe: Up to 30 days

Interventionbreasts (Number)
Treatment Side (Right or Left)2
Placebo Side (Right or Left)1

Number of Participants Requiring a Blood Transfusion

The number of participants requiring blood transfusion was based on the postoperative decline in hematocrit level (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Number of Participants With Deep Vein Thrombosis/Venous Thromboembolism

Incidence of clinically significant deep vein thrombosis or pulmonary embolism detected on imaging (ultrasound or CT scan) (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Blood Loss

"The loss of haemoglobin (Hb) was then estimated according to the formula:~Hb(loss) = Blood volume (BV) x (Hbi-Hbe) x 0.001+Hbt~where Hb (loss) (g) is the amount of Hb lost, Hbi (g/L) the Hb concentration before surgery, Hbe (g/L) is the Hbe concentration on the third day after surgery, and Hbt (g) is the total amount of allogeneic Hb transfused. A unit of banked blood is considered to contain a minimum of 40g Hb (Blood component data sheet, New Zealand Blood Services [NZBS]). All units of blood are processed and stored in a nationally standardised manner. The blood loss (ml) was related to the patient's preoperative Hb value (g/L):~Blood loss =1000 x Hb(loss) /Hbi" (NCT02278263)
Timeframe: Post operative day 3

Interventionmls (Mean)
Control1090
Intraarticular716
Systemic746

Length of Stay (LOS)

Day of surgery is counted as Day 0. (NCT02278263)
Timeframe: Average length of stay is expected to be 3 to 5 days

Interventiondays (Median)
Control4
Topical4
Systemic4

Number of Participants Receiving Allogenic Blood Transfusion

"Those patients receiving blood products. Standardised protocol is as follows:~The criterion for transfusion of blood products will be a haemoglobin < 80g/L or a haemoglobin <100g/L in a patient with ischaemic heart disease or with significant symptomatology" (NCT02278263)
Timeframe: Participants will be followed for the duration of their hospital stay expected to be an average of 3-5 days

InterventionParticipants (Count of Participants)
Control2
Topical1
Systemic0

Perioperative Fluid Administration

Intravenous fluid (excluding blood transfusion) given during and first 24 hours after surgery (NCT02278263)
Timeframe: Day 1

Interventionmls (Mean)
Control1765
Topical1613
Systemic1807

Number of Participants Experiencing Symptomatic Venothromboembolic (VTE) Disease

Rates of deep vein thrombosis (DVT) and pulmonary embolus (PE) in each group recorded as a percentage (NCT02278263)
Timeframe: Postoperatively within 30 days after surgery

,,
InterventionParticipants (Count of Participants)
DVTPE
Control00
Systemic01
Topical02

Range of Active Flexion

Range of motion measured in degrees on postoperative days 1-3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control577175
Systemic587278
Topical657582

Range of Passive Flexion

Range of motion measured in degrees for postoperative days 1 to 3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control657682
Systemic688087
Topical748187

Number of Days Until Drain Removal

The number of days that the post surgical drains remain in place after the surgery. When less than 30 cc per drain in a 24-hour period, the participants are to call and schedule drain removal. (NCT04902950)
Timeframe: Up to 56 days post operatively.

InterventionDays (Mean)
Group 116
Group 222

Number of Participants That Returned to the Operating Room

Return to the operating room for evacuation post surgical operative hematoma or seroma assessed by clinical evaluation to include palpation for ballotable fluid collection and assessment of skin for a shiny/tight appearance suggestive of an underlying fluid collection. (NCT04902950)
Timeframe: Up to 8 weeks postoperatively

InterventionParticipants (Count of Participants)
Group 10
Group 20

Participants With Post Operative Hematoma

Patients will be monitored clinically at each post-operative visit for signs of post-operative hematoma or seroma. Each patient will be evaluated one week, three weeks, and eight weeks following their procedure to assess overall wound healing. (NCT04902950)
Timeframe: Up to 8 weeks postoperatively

InterventionParticipants (Count of Participants)
Group 10
Group 21

Blood Volume Loss

Total blood volume loss will be calculated in milliliters. (NCT03856164)
Timeframe: 24 hours postpartum.

Interventionmilliliters (Mean)
Tranexamic Acid2274
Placebo2407

D-Dimer (µg/mL)

Measured from blood sample collection. (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
Interventionµg/mL (Mean)
Before SurgeryAfter DeliveryP.O.D. 1
Placebo4.03.84.3
Tranexamic Acid2.92.42.1

Fibrinogen (mg/dL)

Measured from blood sample collection. (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
Interventionmg/dL (Mean)
Before SurgeryAfter DeliveryP.O.D. 1
Placebo550.7484.9525.4
Tranexamic Acid563.5499.6527.4

Plasminogen Activator Inhibitor-Type-1 (Units/mL)

Measured from blood sample collection. (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
InterventionIU/mL (Mean)
Before SurgeryAfter DeliveryP.O.D. 1
Placebo61.763.322.1
Tranexamic Acid81.867.020.7

Rotational Thromboelastometry INTEM and EXTEM Clotting Time

Rotational thromboelastometry is a whole blood viscoelastic test that analyzes deficits in clotting factors, clot strength, and clot breakdown. EXTEM, INTEM, and FIBTEM tests measure the extrinsic pathway, intrinsic pathway, and fibrinogen levels, respectively. Compared to non-pregnant patients, FIBTEM/EXTEM/INTEM amplitudes and the FIBTEM maximum clot firmness are higher in pregnant women. The EXTEM and INTEM clotting time are shorter, indicating the relative hypercoagulability of pregnancy. Reference ranges for INTEM Clotting Time (100-240 seconds), INTEM Maximum Clot Firmness (50-72 millimeter), EXTEM Clotting Time (38-79 seconds), EXTEM Maximum Clot Firmness (50-72 millimeter), FIBTEM Maximum Clot Firmness (9-25 millimeter). (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
Interventionseconds (Mean)
Before Surgery INTEM Clotting TimeAfter Delivery INTEM Clotting TimeP.O.D. 1 INTEM Clotting TimeBefore Surgery EXTEM Clotting TimeAfter Delivery EXTEM Clotting TimeP.O.D. 1 EXTEM Clotting Time
Placebo150.5140.7141.256.156.350.2
Tranexamic Acid149.7137.4145.154.054.949.3

Rotational Thromboelastometry INTEM, EXTEM, FIBTEM Maximum Clot Firmness

Rotational thromboelastometry is a whole blood viscoelastic test that analyzes deficits in clotting factors, clot strength, and clot breakdown. EXTEM, INTEM, and FIBTEM tests measure the extrinsic pathway, intrinsic pathway, and fibrinogen levels, respectively. Compared to non-pregnant patients, FIBTEM/EXTEM/INTEM amplitudes and the FIBTEM maximum clot firmness are higher in pregnant women. The EXTEM and INTEM clotting time are shorter, indicating the relative hypercoagulability of pregnancy. Reference ranges for INTEM Clotting Time (100-240 seconds), INTEM Maximum Clot Firmness (50-72 millimeter), EXTEM Clotting Time (38-79 seconds), EXTEM Maximum Clot Firmness (50-72 millimeter), FIBTEM Maximum Clot Firmness (9-25 millimeter). (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
Interventionmillimeter (Mean)
Before Surgery INTEM Maximum Clot FirmnessAfter Delivery INTEM Maximum Clot FirmnessP.O.D. 1 INTEM Maximum Clot FirmnessBefore Surgery EXTEM Maximum Clot FirmnessAfter Delivery EXTEM Maximum Clot FirmnessP.O.D. 1 EXTEM Maximum Clot FirmnessBefore Surgery FIBTEM Maximum Clot FirmnessAfter Delivery FIBTEM Maximum Clot FirmnessP.O.D. 1 FIBTEM Maximum Clot Firmness
Placebo69.468.468.871.269.670.423.922.025.0
Tranexamic Acid69.368.968.870.869.870.524.222.525.8

Tissue Plasminogen Activator Antigen (ng/mL)

Measured from blood sample collection. (NCT03856164)
Timeframe: Collection prior to first drug infusion, immediately before second infusion and 24 hours postpartum.

,
Interventionng/mL (Mean)
Before SurgeryAfter DeliveryP.O.D. 1
Placebo8.29.67.4
Tranexamic Acid8.19.07.5

Length of Hospital Stay

Measured in Days (NCT03825939)
Timeframe: At Hospital Discharge

InterventionDays (Mean)
Intravenous Tranexamic Acid3
Intravenous Placebo3
Intravenous Tranexamic Acid Followed by Intravenous Placebo3

Blood Transfusion Rate

We will record the event of blood transfusion, and calculate the incidence of transfusion (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4

InterventionParticipants (Count of Participants)
Combined Topical TXA and Floseal1
Topical TXA Alone0

Incidence of Thrombosis Events

The composite of any venous thromoembolism events, ischemic heart attacks, cerebrovascular accidents (NCT03328832)
Timeframe: within 30 days of the operation

InterventionParticipants (Count of Participants)
Combined Topical TXA and Floseal0
Topical TXA Alone0

Total Blood Loss After Operation

Total blood loss was calculated according to Nadler et al., which used maximum postoperative reduction of the Hb level adjust for weight and height of the patient. The formula is as follows, Total blood loss = (Total blood volume x [change in Hb level / preoperative Hb level])x1000+volume transfused (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4

Interventionml (Mean)
Combined Topical TXA and Floseal678
Topical TXA Alone733

Therapeutic Effect on Drainage Quantification

The blood quantification will be taken at 6am every day. (NCT02650856)
Timeframe: up to 2nd day post operative (24 and 48 hrs)

,
InterventionmL (Mean)
24 hours48 hours
Group 1 Tranexamic Acid246.4120.8
Group 2 Platelet Rich Plasma263.2140.2

Therapeutic Effect on Hematocrit Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventionpercentage of Hematocrite (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid41.731.629.128.6
Group 2 Platelet Rich Plasma41.529.827.727.3

Therapeutic Effect on Hemoglobin Level

The blood test will be taken at 6am every day. Using the same laboratory parameters. (NCT02650856)
Timeframe: up to 3rd day post operative (Baseline, 24, 48 and 72hrs)

,
Interventiong/dL (Mean)
Baseline24 hours48 hours72 hours
Group 1 Tranexamic Acid13.610.39.59.3
Group 2 Platelet Rich Plasma13.69.99.29.1

Blood Transfusion (Number of Units Transfused) Intraoperatively

Total number of units of blood transfused (whole blood, platelets, cryoprecipitate, and fresh frozen plasma) intra-operatively is a secondary outcome. (NCT02806024)
Timeframe: Pulled from operative note, completed by the time of discharge.

Interventionunits (Mean)
Treatment Arm (Tranexamic Acid, or TXA)5.2
Placebo Arm17.6

Estimated Blood Loss (EBL)

EBL is estimated by the surgeon and anesthesia team at the completion of the surgery (cesarean delivery &/or cesarean hysterectomy). (NCT02806024)
Timeframe: 1-3 hours (will be determined at the completion of the surgery).

Interventioncc (Mean)
Treatment Arm (Tranexamic Acid, or TXA)3116
Placebo Arm9420

Number of Participants With Deep Vein Thrombosis

Must be diagnosed via ultrasound duplex (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group1

Number of Participants With Pulmonary Embolism

Must be diagnosed via CT chest or V/Q lung scan (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Participants With Stroke

Must be diagnosed via CT scan or MRI (NCT02569658)
Timeframe: 30 days post-operative

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Patients Transfused

Patients who received a post-op transfusion of pack red blood cells (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid Group0
Placebo Group0

Number of Units Transfused

Units of pack red blood cells that the patients recieved (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionUnits of PRBCs (Number)
Tranexamic Acid Group0
Placebo Group0

Post-operative Blood Loss

Equated based on the patient's predicted blood volume and change in hemoglobin from the pre-operative level to the lowest post-operative level. (NCT02569658)
Timeframe: Average of 3 days post-operatively

InterventionmL (Mean)
Tranexamic Acid Group152.2
Placebo Group178.0

Change in Hemoglobin

[Key secondary outcome] Change in hemoglobin from the most recent measured before delivery to lowest measured in the 48 hours after delivery (NCT03364491)
Timeframe: from 4 weeks before delivery to 48 hours postpartum

Interventiongrams per deciliter (Mean)
Tranexamic Acid-1.8
Placebo-1.9

Length of Stay

Mother's length of stay from delivery to discharge (NCT03364491)
Timeframe: Until hospital discharge, an average of 3 days

Interventiondays (Median)
Tranexamic Acid3
Placebo3

Number of Mothers Who Died or Had Thromboembolic Events (Venous or Arterial), Ischemic Stroke, Myocardial Infarction, New-onset Seizure Activity, or Were Admitted to the Intensive Care Unit for More Than 24 Hours

(NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid35
Placebo32

Number of Participants Who Received Open Label TXA or Other Antifibrinolytic

This is the number of mothers who were treated with any amount of open-label TXA (not blinded study drug) or another antifibrinolytic (eg., Amicar) (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid108
Placebo109

Number of Participants Who Received Surgical or Radiologic Interventions to Control Bleeding and Related Complications

This is the number of mothers who required any of the following types of surgical procedures to control bleeding: laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid233
Placebo231

Number of Participants Who Received Treatments and Interventions in Response to Bleeding and Related Complications

[Key secondary outcome] This is the number of mothers who received treatments and interventions to control bleeding such as: uterotonics such as prostaglandins or methergine, but excluding oxytocin; open label TXA or other antifibrinolytics; transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets or administration of any factor concentrates; laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid892
Placebo986

Number of Participants Who Were Transfused With 4 or More Units of Packed Red Blood Cells

Participants were categorized according to the amount of packed red blood cells or whole blood transfused, either as 0 to 3 units, or 4 or more units (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid20
Placebo19

Number of Participants Who Were Transfused With Other Blood Products

This is the number of mothers who received during the first 7 days after delivery a transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets, or received any factor concentrates (NCT03364491)
Timeframe: within 7 days postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid29
Placebo31

Number of Participants Who Were Treated With Uterotonics Other Than Oxytocin

This is the number of mothers who were treated with uterotonics such as prostaglandins or methergine, but excluding oxytocin, from delivery through 48 hours after delivery. (NCT03364491)
Timeframe: within 48 hours postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid649
Placebo732

Number of Participants With a Thromboembolic Event (Venous or Arterial), Ischemic Stroke, or Myocardial Infarction

[Key secondary outcome] This is the number of mothers who experienced a thromboembolic event, ischemic stroke, or myocardial infarction during the 6 weeks after delivery. (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid12
Placebo13

Number of Participants With Estimated Blood Loss Greater Than 1 Liter During Delivery

[Major secondary outcome] The surgeon or anesthesiologist estimated the blood loss during the delivery in milliliters, which was recorded in the anesthesia record and/or operative report (NCT03364491)
Timeframe: From skin incision to transfer from operating room, average of 1 hour

InterventionParticipants (Count of Participants)
Tranexamic Acid339
Placebo368

Number of Participants With Maternal Death or Transfusion of Packed Red Blood Cells

Participants were monitored from delivery until hospital discharge or 7 days after delivery (postpartum), whichever is sooner. This is the number of mothers who died for any reason, or had a blood transfusion of 1 or more units (of packed red blood cells, including whole blood or cell saver). (NCT03364491)
Timeframe: by hospital discharge or by 7 days postpartum, whichever is sooner

InterventionParticipants (Count of Participants)
Tranexamic Acid201
Placebo233

Number of Participants With Postpartum Infectious Complications

[Key Secondary Outcome] This is the number of mothers who experienced any of the following infectious complications in the 6 weeks after delivery: endometritis, surgical site infection, pelvic abscess (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid162
Placebo125

Number of Participants With Seizure Activity That Was Not Seen Prior to Study Enrollment

This is the number of mothers who experienced seizure activity, confirmed by central review, whose onset is after enrollment (NCT03364491)
Timeframe: within 6 weeks postpartum

InterventionParticipants (Count of Participants)
Tranexamic Acid2
Placebo0

Complications [VTE (Symptomatic of DVT or PE), Infection (Superficial, Deep), Hematoma, Seroma, Reoperation, and Death]

Incidence of VTE (symptomatic of DVT or PE), infection (superficial, deep), hematoma, seroma, reoperation, and death, measured in person-years ( x cases per 100,000 person years) (NCT02257580)
Timeframe: an expected average of 1 week (post-surgery), Follow-up at 6 weeks

Interventioncases per 100,000 person years (Number)
E-Aminocaproic Acid (EACA)0
Placebo0

Intraoperative Calculated Total Blood Loss

Determined by estimated blood volume, calculated using difference in preoperative and postoperative hemoglobin and applied to the Nadler equation for estimating blood volume while adjusting for transfused hemoglobin to produce a single metric of calculated intraoperative blood loss. (NCT02257580)
Timeframe: Intraoperative (3-6 hours)

InterventionmL (Mean)
E-Aminocaproic Acid (EACA)535.7
Placebo628.0

Intraoperative Cell Saver Utilization

Number of participants requiring 1 unit of intraoperative cell saver transfusion. Patients either received or did not receive intraoperative cell saver transfusion. The maximum number of intraoperative units transfused in this study was 1 unit. The count of participants in the data table refers to the number of patients who received this transfusion. (NCT02257580)
Timeframe: Intraoperative, 1 day

InterventionParticipants (Count of Participants)
E-Aminocaproic Acid (EACA)7
Placebo7

Length of Hospital Stay

postoperative day of discharge after surgery- day of intake. (NCT02257580)
Timeframe: Post-Surgery, an expected average of 1 week

Interventiondays (Mean)
E-Aminocaproic Acid (EACA)5.5
Placebo5.1

Post Operative Blood Loss

24 hour drain output (mL) (NCT02257580)
Timeframe: Post-Surgery, 24 hours

InterventionmL (Mean)
E-Aminocaproic Acid (EACA)72.5
Placebo103.3

Postoperative Allogeneic Blood Transfusion

The number of participants that required 1 unit of blood transfused post-operatively. Patients received blood if necessary post operatively, and the maximum number of units a patient received was 1. The count of participants refers to the number of patients who received this transfusion unit. (NCT02257580)
Timeframe: Post-Surgery, an expected average of 1 week

InterventionParticipants (Count of Participants)
E-Aminocaproic Acid (EACA)4
Placebo3

Blood Transfusion Rates, Defined Nominally (Binary) as Having at Least One Transfusion

To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge

InterventionPatients with 1 or more transfusions (Number)
Tranexamic Acid2
Placebo3

Effect of Tranexamic Acid on the Total Length of Hospital Admission for a Large (350 cm2) Burn Injury

To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge

InterventionDays (Median)
Tranexamic Acid23
Placebo9

Intraoperative Blood Loss in mL

To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes

InterventionmL (Median)
Tranexamic Acid100
Placebo325

Length of Stay in the Emergency Department (Minutes, Median, Inter-Quartile Range)

Length of stay was defined as time from enrollment in study to discharge from the emergency department (NCT02930941)
Timeframe: During emergency department (ED) visit

Interventionminutes (Median)
TXA Group268
NS Group346

Number of Participants With Re-bleeding at 24 Hours

The number of participants with re-bleeding at 24 Hours was evaluated during follow up phone call (NCT02930941)
Timeframe: 24 hours

InterventionParticipants (Count of Participants)
TXA Group3
NS Group9

Number of Participants With Re-bleeding at One Week

The number of participants with re-bleeding at one week was evaluated during the follow-up phone call (NCT02930941)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
TXA Group2
NS Group6

Thromboembolism

Patient reported thromboembolic events during follow-up phone calls at 24 hours and at one week (NCT02930941)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
TXA Group0
NS Group0

Time to Control of Bleeding (Minutes, Median, Interquartile Range)

Time to control of bleeding was defined as the time from the start of enrollment and direct pressure and administration of study drug to the resolution of bleeding (NCT02930941)
Timeframe: During emergency department (ED) visit

Interventionminutes (Median)
TXA Group64
NS Group42

Drug-Related Adverse Events

Patient-reported drug-related adverse events during ED visit (NCT02930941)
Timeframe: during emergency department (ED) visit

,
InterventionParticipants (Count of Participants)
Nasal burningNasal irritationUnpleasant taste
NS Group000
TXA Group201

Cis-atracurium Requirement

Amount of cis-atracurium usage during surgery (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

Interventionmg/kg/hr (Mean)
Group NSS0.08
Group Mg0.08

Fentanyl Requirement

Amount of fentanyl usage during surgery (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

Interventionmcg/kg/hr (Mean)
Group NSS0.65
Group Mg0.6

Intraoperative Blood Loss

We measure the amount of blood loss in the operative room in suction box, gauze and plastic bag. The unit measure is millimeter. (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

Interventionml (Median)
Group NSS510
Group Mg500

Intraoperative Packed Red Cell (PRC) Transfusion

The amount of blood transfusion in patient who required PRC transfusion intraoperatively. (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

Interventionunit of packed red cell (Median)
Group NSS2
Group Mg1

Patient Received Intraoperative Packed Red Cell (PRC)

Number of patients who required Intraoperative PRC transfusion (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

InterventionParticipants (Count of Participants)
Group NSS10
Group Mg7

Postoperative MOCA Score

"MOCA or Montreal Cognitive Assessment is a screening instrument used to facilitate the assessment of cognitive impairment.~MOCA scores range between 0-30, do higher values represent a better outcome. A score of 26 or over is considered to be normal. We measure Montreal assessment score for assess cognitive function after operation at postoperative day 3-7." (NCT03558516)
Timeframe: Postoperative day 3-7

Interventionscore on the MOCA scale (Median)
Group NSS23
Group Mg25

Sevoflurane Requirement

Amount of sevoflurane agents usage during surgery. The unit of measurement of volatile agent is minimum alveolar concentration (MAC). 1 MAC-hour was defined as 2% of sevoflurane for 1 hour duration. (NCT03558516)
Timeframe: Intraoperative period from skin was incised to the skin was closure, an average 5 hours.

Interventionaverage minimum alveolar concentration (Mean)
Group NSS0.65
Group Mg0.66

Blood Loss Volume Following Surgery

Blood loss following surgery was defined as the total amount of fluid collected from the drain in the wound site during the hospital stay. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 5 days

InterventionmL (Median)
Tranexamic Acid534
Placebo530

Change in Hemoglobin Level From Preoperative Appointment to Postoperative Hospital Discharge

Blood loss was calculated from the difference between the level of hemoglobin at the preoperative appointment and the lowest level during the postoperative hospitalization period. Reported here is the change in hemoglobin level after surgery. A negative number indicates a reduction in hemoglobin level. (NCT02063035)
Timeframe: From preoperative appointment approximately one week before surgery to end of hospital stay up to approximately 5 days after surgery

Interventiongrams per deciliter (g/dL) (Median)
Tranexamic Acid-3.2
Placebo-4.6

Hospital Length of Stay in Days

The number of days the participants stayed in the hospital after surgery was recorded. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 2 weeks

Interventiondays (Median)
Tranexamic Acid5
Placebo6

Post-operative Blood Transfusions During Hospitalization

All units of blood transfused during the hospital stay after surgery were recorded. One red blood cell unit contains 300 to 360 mL of whole blood. (NCT02063035)
Timeframe: From end of surgery on Day 1 to end of hospital stay up to approximately 5 days

Interventionunits of blood (Median)
Tranexamic Acid0
Placebo0

Additional Blood Products Transfused

Total additional blood products (fresh frozen plasma, cryoprecipitate, and platelets) transfused in the perioperative period measured in units. (NCT01728636)
Timeframe: 24 hours after skin incision

InterventionUnits (Mean)
Tranexamic Acid1
Placebo2

Estimated Intraoperative Blood Loss

Estimated Intraoperative blood loss in milliliters (mLs) (NCT01728636)
Timeframe: Incision to skin closure (approximately 10 hours)

InterventionMilliliters (Mean)
Tranexamic Acid1550
Placebo1600

Post Operative Major Morbidity

Number of participants who experienced arterial or venous thromboembolism, neurologic complications (including stroke, seizure,and delirium), infections, and pulmonary renal or cardiac adverse outcomes (demand ischemia, myocardial infarction or new arrhythmia) before another operative procedure or hospital discharge. (NCT01728636)
Timeframe: Time of surgery to date of discharge from hospital (average 7 days)

InterventionParticipants (Count of Participants)
Tranexamic Acid9
Placebo9

Total Operating Room Time

Total operating room time from incision to closure of incision in minutes. (NCT01728636)
Timeframe: Minutes

InterventionMinutes (Median)
Tranexamic Acid602
Placebo576

Total Red Blood Cells Transfused in the Intraoperative Period

Total red blood cells transfused in the intraoperative period in (mL). Total RBC equal packed red blood cells and cell saver infusion. (NCT01728636)
Timeframe: Intraoperative period (approximately 12 hours)

Interventionmilliliters (Median)
Tranexamic Acid1140
Placebo1460

Total Tranexamic Acid Dose (mg)

Total milligrams of intravenous tranexamic acid administered during the surgical procedure. (NCT01728636)
Timeframe: Intraoperative period

Interventionmilligrams (Median)
Tranexamic Acid1408
Placebo0

Estimated Blood Loss

Estimated Blood Loss defined as Pre Op Hgb mins the Post Op Day two Hgb. (NCT01866943)
Timeframe: Pre Op, Post Op Day 2

InterventionHemoglobin (grams/deciliter) (Mean)
Baseline Population2.93

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 2 week

Interventionunits on a scale (Mean)
All Study Participants65.76

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 6 week

Interventionunits on a scale (Mean)
All Study Participants81.77

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: Preoperative

Interventionunits on a scale (Mean)
All Study Participants58.34

Mid Thigh Circumference

Measurement of the thigh at the half way point between the prominence of the greater trochanter and the lateral epicondyle of the femur. No data recorded at 2 weeks or 6 weeks for this study population. (NCT01866943)
Timeframe: Pre Op

Interventioncentimeters (Mean)
Baseline Population52.99

Trial Feasibility

Trial accrual (NCT02548910)
Timeframe: through study completion, an average of 2 years

InterventionParticipants (Count of Participants)
Participant Accrual62

Blood Product Transfusion Rates

(NCT02548910)
Timeframe: Will be measured in the operating room and in the first postoperative week

,
InterventionParticipants (Count of Participants)
IntraoperativePostoperativeTotal
Control134
Phlebotomy155

Change in Physiologic Parameters (Cardiac Index)

(NCT02548910)
Timeframe: Will be measured in the operating room

,
InterventionI per min per m2 (Median)
Before transectiontransection
Control4.23.9
Phlebotomy3.53.5

Changes in Physiologic Parameters (CVP)

(NCT02548910)
Timeframe: Will be measured in the operating room

,
InterventioncmH2O (Median)
before transectiontransection
Control77.5
Phlebotomy88

Perioperative Morbidity (Dindo-Clavien Grade 3b of Higher) and Mortality

(NCT02548910)
Timeframe: Postoperative setting up to 30 days following surgery

,
InterventionParticipants (Count of Participants)
postoperative complicationsMajor complication
Control153
Phlebotomy102

Total Intraoperative Blood Loss, by Measurement of Change in Hemoglobin Levels

Intraoperative blood loss is notoriously difficult to measure. It is suggested that calculation of blood loss using preoperative and postoperative hemoglobin levels in most consistently accurate. In order to minimize the risk of bias associated with any one method of intraoperative measurement of blood loss, three methods will be used independently. In the operating room, all blood and fluid aspirated from the abdomen will be measured accurately using graduated suction containers. As well, the amount of irrigation fluid will be carefully monitored and recorded. Finally, the weight of all surgical sponges will be measured. This information will be used by the surgeon and anesthesiologist to independently visually estimate blood loss, as is commonly done in clinical practice. In parallel, intraoperative blood loss will also be calculated based on an equation. (NCT02548910)
Timeframe: 1 week prior to surgery (hemoglobin level), and day two of post-op (hemoglobin again).

,
InterventionmL (Median)
Anaesthetist EstimateSurgeon EstimateCalculated EBL
Control8728721249
Phlebotomy8627611116

Number of Units of Packed Red Blood Cells (PRBC) Transfused Following Coronary Artery Bypass Graft Surgery

Research participants were to receive a blood transfusion in the Intensive Care Unit (ICU) post-operatively if hemoglobin reached a nadir of 80g/L, or at the discretion of the intensivist or cardiac surgeon according to patient clinical status. Transfusion was quantified based on the number of units of PRBC received. (1 unit = 1 bag of blood, as prepared by Canadian Blood Services). Clinical status of research participants was followed throughout their duration in the ICU only. Participation in this study ended upon transfer out of the ICU, to the Cardiology Ward. (NCT01519245)
Timeframe: From ICU admission to transfer to the Cardiology Ward (placebo group = 24.4 hours; trial group = 24.7 hours)

InterventionUnit(s) of PRBC (Number)
Trial Drug0
Placebo0

Total Volume of Blood Loss From Mediastinal Chest Tubes at Time of Removal (Assuming the Total Volume of Loss is Blood).

According to standard practice, research participants were be transferred to the intensive care unit (ICU) for post-operative monitoring. Measurement of chest tube output began immediately on arrival to the ICU. Hourly measurements were recorded. Data collection ended upon chest tube removal, or return to the operating room for exploratory surgery due to massive blood loss. As per ICU protocol, chest tubes were be removed when blood loss was recorded to be less than 200mL after six consecutive hours. (NCT01519245)
Timeframe: From ICU admission post-operatively to mediastinal chest tube removal (placebo group = 20.6 hours; trial group = 19.8 hours)

InterventionmL (Mean)
Trial Drug632
Placebo789

Volume of Blood Loss After 12 Hours

Volume of chest tube loss at 12 hours (assuming the total volume of loss is blood). (NCT01519245)
Timeframe: 12 hours following admission to the Intensive Care Unit

InterventionmL (Mean)
Trial Drug464
Placebo570

Volume of Blood Loss at 6 Hours

Volume of chest tube loss at 6 hours (assuming the total volume of loss is blood). (NCT01519245)
Timeframe: 6 hours following admission to the Intensive Care Unit

InterventionmL (Mean)
Trial Drug342
Placebo417

Allogenic Blood Transfusion Rates

Number of participant received allogenic blood transfusions. (NCT02684851)
Timeframe: post-operative

InterventionParticipants (Count of Participants)
Tranexamic21
Placebo13

Estimate Blood Loss

To measure average estimate perioperative blood loss (NCT02684851)
Timeframe: perioperative

InterventionmL (Mean)
Tranexamic727.6
Placebo560.1

Number of Participants With a Thromboembolic Event

Do patients undergoing acetabular ORIF who receive tranexamic acid have a higher risk for thromboembolic events than patients who receive placebo? (NCT02684851)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Tranexamic1
Placebo0

Units of Packed Red Blood Cells Transfused

Average units packed red blood cells transfused among participants (NCT02684851)
Timeframe: perioperative

InterventionUnits of packed red blood cells (Mean)
Tranexamic2.65
Placebo2.36

Document Incidences of DVT and Other Thromboembolic Events.

"DVT = Deep Venous thrombosis~Patients were assessed every 12 hours for development of pain within the lower extremity. Any reported muscle pain was evaluate with a bedside venous ultrasound by an ultrasound technician." (NCT01651806)
Timeframe: 1 year

InterventionEvents (Number)
Female Uniform Single Dose TA Patient1
Female Weighted Dose TA Patient1
Control0
Male Uniform Single Dose TA0
Male Weighted Dose TA0

Primary Intra-operative Blood Loss

Record intra-operative blood loss through drain output (NCT01651806)
Timeframe: Intra-operative, an average of 3 hours

InterventionmL (Mean)
Female Uniform Single Dose TA Patient100.00
Female Weighted Dose TA Patient65.00
Control142.80
Male Uniform Single Dose TA100.00
Male Weighted Dose TA Patient65.00

Total Blood Loss Over Course of Stay (Intraoperative and Postoperatively Until Discharge)

(NCT00958581)
Timeframe: 1 Week

Interventionml (Mean)
Epsilon Aminocaproic Acid1775
Normal Saline2116
Tranexamic Acid1531

Number of Patients Required Blood Transfusion

(NCT01850394)
Timeframe: postoperative period (5 days after surgery)

Interventionparticipants (Number)
Control Group10
TXA-250 Group6
TXA-500 Group0

Total Hemoglobin Loss

Total hemoglobin loos measured by difference between hemoglobin preoperatively and the fourth postoperative day (NCT01850394)
Timeframe: 5 days after surgery

Interventiong/dL (Mean)
Control Group2.9
TXA-250 Group2.2
TXA-500 Group2.2

Knee Function Scores

"Knee function score was measured with 2 methods, and were evaluated preoperatively and then postoperatively at 3-month, 6-month, and 1-year period.~Knee Society Knee Score using for rating knee function measurement and subdivided into two parts; knee score and function score 1.1. Knee score : calculated from pain, presence of deformity, total range of flexion, alignment, and stability. Total score is 100 (0-100), more score means better.~1.2. Function score : calculated from patient's ability to walk and climb stairs. The score ranges from 0-100, more score means better.~Western Ontario and McMaster Universities Arthritis Index or WOMAC score : a widely used, standardized questionnaires for evaluating the condition of patients with knee osteoarthritis, including pain (score = 0-20), stiffness (0-8), and functional limitation (0-68). Total score ranges from 0-68, lower score means better." (NCT01850394)
Timeframe: 1 year after surgery

,,
Interventionunits on a scale (Mean)
Knee Society Knee score at 1 yearWOMAC score at 1 year
Control Group148.915.5
TXA-250 Group151.215.1
TXA-500 Group150.914.5

Number of Patients Having Postoperative Complications

"Postoperative complications were measured as an incidence of the following complications;~wound hematoma~surgical site infection~systemic infection~deep vein thrombosis~pulmonary embolism~knee stiffness requiring manipulation~medical complication such as myocardial infarction, congestive hear failure" (NCT01850394)
Timeframe: postoperative 1-year period

,,
Interventionparticipants (Number)
Re-clamp incidenceRe-dressing incidenceVenous thromboembolic complicationCongestive heart failure
Control Group6340
TXA-250 Group1011
TXA-500 Group0020

Perioperative Blood Loss

"Drainage blood loss measured by accumulating total drainage volume postoperatively~Calculated total blood loss measured by using specific formula and difference between hematocrit preoperatively and the fourth postoperative day" (NCT01850394)
Timeframe: 5 days after surgery

,,
Interventionml (Median)
Drainage blood lossCalculated total blood loss
Control Group546.9329.2
TXA-250 Group475.0239.7
TXA-500 Group430.2217.2

Perioperative Blood Loss

Perioperative blood loss (during operation and for entire hospital admission) (NCT01813058)
Timeframe: perioperarively - during entire hospital admission

InterventionmL (Mean)
Placebo1031
Tranexamic Acid836

Cumulative Volume of Packed Red Blood Cells Transfused

(NCT00888940)
Timeframe: 12 hours after the end of surgery

InterventionmL (Mean)
Ecallantide1223.2
Cyklokapron(R)623.5

Treatment-emergent Adverse Events.

(NCT00888940)
Timeframe: Over the duration of the study.

,
Interventionevents (Number)
At Least 1 TEAEAt Least 1 Related TEAEAt Least 1 Severe TEAEAt Least 1 Serious TEAEAt Least 1 Related & Serious TEAEPremature Study Drug Discontinuations Due to TEAERelated TEAE Resulting in Discontinuation of DrugTEAE Resulting in DeathRelated TEAE Resulting in Death
Cyklokapron(R)945172812040
Ecallantide10053845420130

Estimated Blood Loss

Surgical blood loss estimation (NCT01980355)
Timeframe: From time of surgery to 90 days post hospital discharge

InterventionmL (Median)
Tranexamic Acid450
Placebo365

Number of Participants Who Required Transfusion

To determine the impact of perioperative administration of tranexamic acid on blood loss and transfusion rates in major oncologic surgery (NCT01980355)
Timeframe: From time of surgery to 90 days post hospital discharge

InterventionParticipants (Count of Participants)
Tranexamic Acid8
Placebo5

Number of Participants Experiencing Deep Vein Thrombosis

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Deep venous thrombosis" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Hematoma as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Hematoma" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Infection as a Surgical Site Complication

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Infection" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Number of Participants Experiencing Myocardial Infarction

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Myocardial infarction" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline1

Number of Participants Experiencing Pulmonary Embolism

"The occurrence of the following systemic and surgical site complications within 6 weeks of surgery will be recorded. Data will be obtained from EMR and from patient at standard of care 2 week and 6 week follow-up appointment.~Pulmonary Embolism" (NCT02043132)
Timeframe: up to 6-weeks post-operatively

InterventionParticipants (Count of Participants)
Tranexamic Acid0
Normal Saline0

Total Blood Loss

Total Blood Loss as calculated according to method as described by Good et al. Total Blood Loss (mL) = 1000 X Hb(loss)/Hb(initial) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

InterventionTotal Blood Loss (mL) (Mean)
Tranexamic Acid1122.4
Normal Saline1472

Total Drain Output

Total Drain Output as measured postoperatively 0-48 hours (NCT02043132)
Timeframe: 0-48 hours postoperatively

InterventionmL (Mean)
Tranexamic Acid221
Normal Saline372

Total Hemoglobin Loss

Total hemoglobin loss estimated using the formula for total blood volume described by Nadler et al Hb(loss) = blood volume (L) x [Hb(initial)(g/L) - Hb(final)(g/L)] + Hb(transfused) (NCT02043132)
Timeframe: Preoperative through Postoperative Days 1 and 2

Interventiong (Mean)
Tranexamic Acid154.6
Normal Saline200.1

Number of Participants Requiring Surgical Re-exploration

the secondary objective of this study is to determine whether pericardial lavage with saline gives an improvement in haemostasis, compared with no pericardial lavage, resulting in a reduction of surgical re-explorations and post-operative 12-hour blood loss. The choice for a surgical re-exploration will be decided according to the ICU protocol. (NCT01895101)
Timeframe: participants will be followed for the duration of ICU stay, an expected average of 2 days

Interventionparticipants (Number)
Pericardial Lavage With 200 ml Normothermic Saline Solution10
No Pericardial Lavage9
2 gr Tranexamic Acid Diluted in 200 ml Normothermic Saline12

Postoperative Blood Loss

The primary study parameter is 12 hours postoperative blood loss and is assessed by postoperative chest tube production. Postoperative chest tube production 12 hours after surgical procedure (NCT01895101)
Timeframe: 12 hours postoperative

Interventionml (Median)
Pericardial Lavage With 200 ml Normothermic Saline Solution290
No Pericardial Lavage300
2 gr Tranexamic Acid Diluted in 200 ml Normothermic Saline290

Total Red Blood Cell Transfusions (Cumulative of Pre, Peri and Postoperative Period)

The amount of red blood cell transfusions the patient receive pre, peri and postoperatively during their stay in the hospital. (NCT01895101)
Timeframe: participants will be followed for the duration of ICU stay, an expected average of 2 days/ And participants will be followed for the duration of hospital stay, an expected average of 3 weeks

InterventionIU (Mean)
Pericardial Lavage With 200 ml Normothermic Saline Solution0.7
No Pericardial Lavage1.1
2 gr Tranexamic Acid Diluted in 200 ml Normothermic Saline0.7

Median Number of Transfused Units of Red Blood Cells (RBC)

Median number of red blood cells transfused among those who received RBC transfusions (NCT00740116)
Timeframe: From start of operation to discharge from hospital, up to 5 weeks

Interventionunits (Median)
The Placebo Group2
The Tranexamic Acid Group2

Number of Patients Receiving Blood Transfusions

Total number of RBC-transfused women in each group (NCT00740116)
Timeframe: From start of operation to discharge from hospital, up to 5 weeks

Interventionparticipants (Number)
Tranexamic Group15
Placebo Group22

Number of Patients With Clinically or Radiologically Verified Thromboembolic Events Within 5 Weeks Postoperatively

Thromboembolic events including arterial thrombosis, muscle vein thrombosis, superficial and deep venous thrombosis. (NCT00740116)
Timeframe: From time of operation to 5 weeks postoperatively.

InterventionParticipants (Count of Participants)
Tranexamic Group2
Placebo Group5

Number of Units of Red Blood Cells (RBC) Transfused

Total number of red blood cells (RBC) transfused across all participants (NCT00740116)
Timeframe: From start of operation to discharge from hospital, up to 5 weeks

Interventionunits (Number)
Tranexamic Group38
Placebo Group53

Perioperative Bleeding Volume

Estimation of total blood loss was based on the estimation of the Hb balance method (Brecher, et al.1997) with the assumption that the body blood volume was normalised on the fifth postoperative day. The haemoglobin level was assessed preoperatively and on the fifth postoperative day. The predicted blood volume (PBV, l) was calculated according to the method described by Nadler et al. (1962), using body weight and height. The extravasation of haemoglobin was calculated taking into account allogenic transfused haemoglobin. Total blood loss perioperatively was related to the patient's preoperative haemoglobin value. Blood loss due to haematomas or a reoperation within the first five days after surgery was also considered. (NCT00740116)
Timeframe: From start of operation to discharge from hospital, up to 5 weeks

Interventionmilliliter (Median)
Tranexamic Group520
Placebo Group730

Functional Outcomes

"Functional outcomes measured by the 2011 Knee Society Score. The Functional Activities section consists of 4 sub-sections with a total score ranging from 0-100 points. The higher the numerical value the better the outcome. The sub-sections consist of: (1)Walking and Standing 0-30 points (2)Standard Activities 0-30 points (3)Advanced Activities 0-25 points (4)Discretionary Knee Activities 0-15 points." (NCT03952546)
Timeframe: 8 weeks

Interventionscore on a scale (Mean)
Treatment Arm56.45
Control Arm61.79

Hemostasis

Postoperative day 1 estimated blood loss as calculated by the Gross' Formula (NCT03952546)
Timeframe: Postoperative day 1

Interventionmilliliters (Mean)
Treatment Arm924
Control Arm1062

Wound Infection

Participants were assessed for any wound infection within 90 days of surgery. (NCT03952546)
Timeframe: 90 days postoperatively

InterventionNumber of events (Number)
Saline-Coupled Bipolar Sealer1
Unipolar Electrocautery3

Number of Patients That Remained Transfusion Free

(NCT00722436)
Timeframe: 24 hours

Interventionparticipants (Number)
Tranexamic Acid2
Placebo0

Total Volume (ml/kg) of Allogeneic Blood Exposure.

This is the blood administered during surgery. The blood comes form the blood bank. It is not cell salvage blood. The volume was normalized by weight. (NCT00722436)
Timeframe: intraoperative and postoperative (24 hr)

Interventionml/kg (Mean)
Tranexamic Acid16.1
Placebo17.1

Effect of Tranexamic Acid on Prothrombin Time (PT), Partial Thromboplastin Time (PTT) at Three Time Points (Baseline, After Osteotomies, and Immediately After Procedure).

(NCT00722436)
Timeframe: (baseline, after osteotomies, and immediately after procedure)

,
Interventionseconds (Mean)
PT -baselinePT-after osteotomiesPT-immediately after surgeryPTT -baselinePTT-after osteotomiesPTT-immediately after surgery
Placebo13.816.11732.934.634.8
Tranexamic Acid15.118.517.734.637.233.3

Platelets

(NCT00722436)
Timeframe: baseline, after osteotomies, immediately after surgery

,
Intervention10^9 platelets/L (Mean)
platelets-baselineplatelets-after osteotomiesplatelets-immediately after surgery
Placebo364300231
Tranexamic Acid301253223

Plasmin-alpha-2-antiplasmin Complex (PAP), a Marker of Fibrinolysis

Study patients received 100 mg of intravenous hydrocortisone 2 h prior to surgery, and controls received normal saline. Blood samples, drawn pre-incision and at 4 h post tourniquet release, were assayed for PF1.2 and PAP (NCT01815918)
Timeframe: Baseline and up to 4 hours following surgery

,
Interventionug/L (Mean)
Baseline4 hs
Placebo623.31086.8
Treatment808.41638.6

Prothrombin Fragment (PF1.2), a Marker of Thrombin Generation

Study patients received 100 mg of intravenous hydrocortisone 2 h prior to surgery, and controls received normal saline. Blood samples, drawn pre-incision and at 4 h post tourniquet release, were assayed for PF1.2 and PAP (NCT01815918)
Timeframe: Baseline and up to 4 hours following surgery

,
InterventionpMol/L (Mean)
Baseline4s
Placebo263.6935.8
Treatment266.5615.9

Reviews

363 reviews available for tranexamic acid and Blood Loss, Surgical

ArticleYear
A Systematic Review and Meta-Analysis Evaluating the Impact of Tranexamic Acid Administration in Aesthetic Plastic Surgery.
    Aesthetic surgery journal, 2022, 04-12, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Female; Hematoma; Humans; Surgery, Plasti

2022
The efficacy of Tranexamic Acid Administration in Patients Undergoing Tonsillectomy: An Updated Meta-Analysis.
    The Annals of otology, rhinology, and laryngology, 2022, Volume: 131, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorrhage; Tonsillectomy; Tran

2022
The Efficacy and Safety of Tranexamic Acid in the Management of Perioperative Bleeding After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis of Comparative Studies.
    Journal of endourology, 2022, Volume: 36, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Nephrolithotomy, Percutaneous; Postoperative

2022
Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac Surgery on Cardiopulmonary Bypass: A Systematic Review and Meta-analysis.
    Anesthesia and analgesia, 2022, 05-01, Volume: 134, Issue:5

    Topics: Aminocaproic Acid; Anaphylaxis; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Su

2022
Blood Loss and Transfusion in a Pediatric Scoliosis Surgery Cohort in the Antifibrinolytic Era.
    Journal of pediatric hematology/oncology, 2022, Apr-01, Volume: 44, Issue:3

    Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Humans; Retrosp

2022
Tranexamic Acid Administration in Arthroscopic Surgery Is a Safe Adjunct to Decrease Postoperative Pain and Swelling: A Systematic Review and Meta-analysis.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2022, Volume: 38, Issue:4

    Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthroscopy; Blood Loss, Surgical; Female; Hemarth

2022
Tranexamic acid in head and neck procedures: a systematic review and meta-analysis of randomized controlled trials.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022, Volume: 279, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Postoperative Hemorrhage; Random

2022
Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials.
    Injury, 2022, Volume: 53, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Randomized Controlled Tr

2022
Tranexamic acid in sinus and nasal surgery: an up-to-date meta-analysis.
    The Journal of laryngology and otology, 2022, Volume: 136, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Nasal Surgical Procedures; Paranasal Sinuses;

2022
Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice.
    Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2022
Association of tranexamic acid with decreased blood loss in patients undergoing laminectomy and fusion with posterior instrumentation: a systematic review and meta-analysis.
    Journal of neurosurgery. Spine, 2022, 04-01, Volume: 36, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Laminectomy; Tranexamic Ac

2022
Safety and Efficacy of Tranexamic Acid to Minimise Perioperative Bleeding in Hepatic Surgery: A Systematic Review and Meta-Analysis.
    World journal of surgery, 2022, Volume: 46, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Liver; Tranexamic Acid

2022
Tranexamic Acid versus Epsilon-Aminocaproic Acid in Total Knee Arthroplasty: A Meta-Analysis.
    Journal of healthcare engineering, 2021, Volume: 2021

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; H

2021
Efficacy and safety of aprotinin in paediatric cardiac surgery: A systematic review and meta-analysis.
    European journal of anaesthesiology, 2022, Apr-01, Volume: 39, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; C

2022
Effect of Tranexamic Acid on Bleeding Outcomes After Percutaneous Nephrolithotomy: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    Journal of endourology, 2022, Volume: 36, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Nephrolithotomy, Percutaneous; Ra

2022
Tranexamic Acid: When is It Indicated in Orthopaedic Surgery?
    Zeitschrift fur Orthopadie und Unfallchirurgie, 2023, Volume: 161, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Blood Transfusion; Humans;

2023
Commentary on: A Systematic Review and Meta-Analysis Evaluating the Impact of Tranexamic Acid Administration in Aesthetic Plastic Surgery.
    Aesthetic surgery journal, 2022, 04-12, Volume: 42, Issue:5

    Topics: Blood Loss, Surgical; Humans; Plastic Surgery Procedures; Surgery, Plastic; Tranexamic Acid

2022
The administration of tranexamic acid for corrective surgery involving eight or more spinal levels: A systematic review and meta-analysis.
    Asian journal of surgery, 2022, Volume: 45, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Humans; Spine; Trane

2022
Role of tranexamic acid in craniosynostosis surgery: Systematic review and meta-analysis.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2022, Volume: 75, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; Prospective Studies;

2022
Use of Tranexamic Acid for Elective Resection of Intracranial Neoplasms: A Systematic Review.
    World neurosurgery, 2022, Volume: 160

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Brain Neoplasms; Humans; Prospective Studies; Retrosp

2022
    Journal of endourology, 2022, Volume: 36, Issue:5

    Topics: Blood Loss, Surgical; Humans; Nephrolithotomy, Percutaneous; Randomized Controlled Trials as Topic;

2022
Impact of tourniquet during total knee arthroplasty when tranexamic acid was used: a meta-analysis of randomized controlled trials.
    Journal of orthopaedic surgery and research, 2022, Jan-15, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Intraoperati

2022
Tranexamic Acid Use for Hemorrhagic Events Prevention in Percutaneous Nephrolithotomy: Systematic Review and Meta-Analysis.
    Journal of endourology, 2022, Volume: 36, Issue:7

    Topics: Blood Loss, Surgical; Blood Transfusion; Humans; Kidney Calculi; Lithotripsy; Nephrolithotomy, Percu

2022
Safety and Efficacy of Local Tranexamic Acid for the Prevention of Surgical Bleeding in Soft-Tissue Surgery: A Review of the Literature and Recommendations for Plastic Surgery.
    Plastic and reconstructive surgery, 2022, Mar-01, Volume: 149, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Plastic Surgery Procedures; Tranexamic Acid;

2022
Tranexamic acid reduces postoperative blood loss in Chinese pediatric patients undergoing cardiac surgery: A PRISMA-compliant systematic review and meta-analysis.
    Medicine, 2022, Mar-04, Volume: 101, Issue:9

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Cardiac Surgical Procedu

2022
Tranexamic acid-associated fatal status epilepticus in a paediatric non-cardiac surgery: A case report and literature review.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Humans; Male; Propofol; Seiz

2022
The effect of antifibrinolytic agents in periacetabular osteotomy: A systematic review and meta-analysis.
    Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Osteotomy; Tranexamic Acid

2022
The use of tranexamic acid reduces blood loss in osteotomy at knee level: a systematic review.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022, Volume: 30, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Osteotomy; Postoperative Hemorrh

2022
The efficacy and safety of tranexamic acid in lumbar surgery: A meta-analysis of randomized-controlled trials.
    Joint diseases and related surgery, 2022, Volume: 33, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; R

2022
Intra-articular versus intravenous administration of tranexamic acid in lower limb total arthroplasty: a systematic review and meta-analysis of randomised clinical trials.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Impact on blood loss and transfusion rates following administration of tranexamic acid in major oncological abdominal and pelvic surgery: A systematic review and meta-analysis.
    Journal of surgical oncology, 2022, Volume: 126, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Pelvic Neoplasms; Tranexamic Acid; Venous Thr

2022
[Hemostatic efficacy of tranexamic acid and ε-aminocaproic acid in hip and knee arthroplasty:a Meta-analysis].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2022, May-25, Volume: 35, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacemen

2022
Tranexamic Acid and Its Potential Anti-Inflammatory Effect: A Systematic Review.
    Seminars in thrombosis and hemostasis, 2022, Volume: 48, Issue:5

    Topics: Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surg

2022
Intravenous tranexamic acid and thromboembolic events in hip fracture surgery: A systematic review and meta-analysis.
    Orthopaedics & traumatology, surgery & research : OTSR, 2023, Volume: 109, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemoglobins; Hip Frac

2023
Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Intertrochanteric Fracture.
    The Journal of bone and joint surgery. American volume, 2022, 07-06, Volume: 104, Issue:13

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2022
The efficacy and safety of combined administration of intravenous and intra-articular tranexamic acid in total knee arthroplasty: An update meta-analysis.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:9

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2022
Prophylactic tranexamic acid during myomectomy: A systematic review and meta-analysis of randomized controlled trials.
    European journal of obstetrics, gynecology, and reproductive biology, 2022, Volume: 276

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Randomized Controlled Trials as Topic

2022
Tranexamic acid dosage for spinal surgery: a meta-analysis.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2022, Volume: 31, Issue:10

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Human

2022
Is Tranexamic Acid Beneficial in Open Spine Surgery? and its Effects Vary by Dosage, Age, Sites, and Locations: A Meta-Analysis of Randomized Controlled Trials.
    World neurosurgery, 2022, Volume: 166

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; Spinal

2022
Optimal administration strategies of tranexamic acid to minimize blood loss during spinal surgery: results of a Bayesian network meta-analysis.
    Annals of medicine, 2022, Volume: 54, Issue:1

    Topics: Antifibrinolytic Agents; Bayes Theorem; Blood Loss, Surgical; Humans; Network Meta-Analysis; Tranexa

2022
The effect of tranexamic acid in open reduction and internal fixation of pelvic and acetabular fracture: A systematic review and meta-analysis.
    Medicine, 2022, Jul-22, Volume: 101, Issue:29

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; P

2022
Optimizing Blood Loss and Management in Craniosynostosis Surgery: A Systematic Review of Outcomes Over the Last 40 Years.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2023, Volume: 60, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Humans; Tranexam

2023
Effect of Tranexamic Acid on Blood Management during a High Tibial Osteotomy: A Systematic Review and Meta-analysis.
    Orthopaedic surgery, 2022, Volume: 14, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemoglobins; Humans; Male; Osteotomy; Tranexa

2022
The effect of tranexamic acid on myocardial injury in cardiac surgical patients: a systematic review and meta-analysis.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2022, Dec-01, Volume: 33, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Human

2022
Update on Applications and Limitations of Perioperative Tranexamic Acid.
    Anesthesia and analgesia, 2022, 09-01, Volume: 135, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Child; Humans; Periopera

2022
Update on Applications and Limitations of Perioperative Tranexamic Acid.
    Anesthesia and analgesia, 2022, 09-01, Volume: 135, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Child; Humans; Periopera

2022
Update on Applications and Limitations of Perioperative Tranexamic Acid.
    Anesthesia and analgesia, 2022, 09-01, Volume: 135, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Child; Humans; Periopera

2022
Update on Applications and Limitations of Perioperative Tranexamic Acid.
    Anesthesia and analgesia, 2022, 09-01, Volume: 135, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Child; Humans; Periopera

2022
Tranexamic Acid Utilization in Foot and Ankle Surgery: A Meta-analysis.
    Foot & ankle international, 2022, Volume: 43, Issue:10

    Topics: Administration, Intravenous; Ankle; Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Huma

2022
The Safety and Effectiveness of Tranexamic Acid in Lumbar Interbody Fusion Surgery: An Updated Meta-analysis of Randomized Controlled Trials.
    World neurosurgery, 2022, Volume: 166

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Randomized Controlled Trials as

2022
Update on the efficacy and safety of intravenous tranexamic acid in hip fracture surgery: a systematic review and meta-analysis.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; P

2023
Patient blood management and patient safety.
    Current opinion in anaesthesiology, 2022, Dec-01, Volume: 35, Issue:6

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Patient Safety; Tranexamic Acid

2022
Comparison between peri-articular injection and intra-articular injection of tranexamic acid during total knee arthroplasty: A meta-analysis.
    Joint diseases and related surgery, 2022, Volume: 33, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Injections,

2022
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Efficacy and safety of tranexamic acid in unicompartmental knee arthroplasty: A systematic review and meta-analysis.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
The Use of Tranexamic Acid in Hip Fracture Surgery-A Systematic Review and Meta-analysis.
    Journal of orthopaedic trauma, 2022, 12-01, Volume: 36, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2022
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
    Thrombosis research, 2023, Volume: 221

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
Efficacy of prophylactic pre-operative desmopressin administration during functional endoscopic sinus surgery for chronic rhinosinusitis: A systematic review and meta-analysis of randomised placebo-controlled trials.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2023, Volume: 48, Issue:2

    Topics: Blood Loss, Surgical; Deamino Arginine Vasopressin; Hemostatics; Humans; Randomized Controlled Trial

2023
The role of tranexamic acid in reducing post-operative bleeding and seroma formation in breast surgery: A meta-analysis.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2023, Volume: 21, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Seroma; T

2023
Efficacy and safety of tranexamic acid in posterior lumbar interbody fusion: a meta-analysis of randomized controlled trials.
    Journal of orthopaedic surgery and research, 2023, Jan-05, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; System

2023
A systematic review and meta-analysis of the effects of tranexamic acid in surgical procedure for intracranial meningioma.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Meningeal Neoplasms; Meningioma; Middl

2023
Is tranexamic acid associated with decreased need for blood transfusion in percutaneous nephrolithotomy: a systematic review and meta-analysis.
    Annals of the Royal College of Surgeons of England, 2023, Volume: 105, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Nephrolithotomy, Percutane

2023
Tranexamic Acid Use in Breast Surgery: A Systematic Review and Meta-Analysis.
    Plastic and reconstructive surgery, 2023, 05-01, Volume: 151, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Mastectom

2023
Efficacy of high dose tranexamic acid (TXA) for hemorrhage: A systematic review and meta-analysis.
    Injury, 2023, Volume: 54, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemorrhage; Humans; Randomi

2023
Surgeon-Specific Treatment Selection Bias and Heterogeneous Perioperative Practices in an Observational Spine Surgery Study. A Statistical Tutorial with Implications for Analysis of Observational Studies of Perioperative Interventions.
    World neurosurgery, 2023, Volume: 173

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Retrospective Studies; Selection Bias;

2023
Tranexamic acid use in meningioma surgery - A systematic review and meta-analysis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2023, Volume: 110

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Meningeal Neoplasms; Meningioma; Tranexamic A

2023
Local Application of Tranexamic Acid in Plastic Surgery Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Aesthetic plastic surgery, 2023, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Randomized Controlled Trials as T

2023
The Efficacy of Tranexamic Acid for the Treatment of Traumatic Hip Fractures: A Network Meta-Analysis.
    Journal of orthopaedic trauma, 2023, 07-01, Volume: 37, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Network Meta-Analysis; Randomi

2023
CONTEMPORARY RECOMMENDATIONS ON PATIENT BLOOD MANAGEMENT IN JOINT ARTHROPLASTY.
    Acta clinica Croatica, 2022, Volume: 61, Issue:Suppl 2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2022
Tranexamic acid-associated intrathecal toxicity during spinal anaesthesia: A narrative review of 22 recent reports.
    European journal of anaesthesiology, 2023, 05-01, Volume: 40, Issue:5

    Topics: Anesthesia, Spinal; Anesthetics, Local; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemor

2023
The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.
    Orthopaedic surgery, 2023, Volume: 15, Issue:4

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
Role of Tranexamic Acid (TXA) in Preventing Bleeding Following Sleeve Gastrectomy: a Systematic Review and Meta-analysis.
    Obesity surgery, 2023, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Gastrectomy; Humans;

2023
The Effects of Tranexamic Acid in Breast Surgery: A Systematic Review and Meta-Analysis.
    Plastic and reconstructive surgery, 2023, 12-01, Volume: 152, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Hematoma; Humans; Postopera

2023
A systematic review on the efficacy of tranexamic acid in head and neck surgery.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2023, Volume: 48, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorrhage; Tonsillectom

2023
Modern use of tranexamic acid in facial plastic surgery.
    Current opinion in otolaryngology & head and neck surgery, 2023, Aug-01, Volume: 31, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Plastic Surgery Procedures; Rhinoplasty; Surg

2023
Tranexamic acid in endoscopic sinus and skull base surgery: A systematic review and meta-analysis.
    International forum of allergy & rhinology, 2023, Volume: 13, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Paranasal Sinuses; Skull Base; Tranexamic Aci

2023
Tranexamic acid in burn surgery: A systematic review and meta-analysis.
    Burns : journal of the International Society for Burn Injuries, 2023, Volume: 49, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Burns; Humans; Tranexamic Acid; Venous Thromboembolis

2023
Effect of preoperative prophylactic intravenous tranexamic acid on perioperative blood loss control in patients undergoing cesarean delivery: a systematic review and meta-analysis.
    BMC pregnancy and childbirth, 2023, Jun-06, Volume: 23, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female

2023
Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials.
    American journal of obstetrics & gynecology MFM, 2023, Volume: 5, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Postpartum Hemorrha

2023
Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis.
    Anaesthesia, 2023, Volume: 78, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Thr

2023
Effects of combined dexamethasone and tranexamic acid in lower limb total arthroplasty: a systematic review and meta-analysis of randomized clinical trials.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:8

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
Efficacy and safety of intravenous tranexamic acid in urologic surgery: A systematic review and meta-analysis of randomized controlled trials.
    Medicine, 2023, Jun-23, Volume: 102, Issue:25

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; Thromb

2023
Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement,

2023
Intravenous application of tranexamic acid in intramedullary nailing for the treatment of geriatric intertrochanteric fractures: a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2023, Jul-27, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation,

2023
Effectiveness of tranexamic acid in orthognathic surgery: A systematic review of systematic reviews.
    Journal of stomatology, oral and maxillofacial surgery, 2023, Volume: 124, Issue:6S2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthognathic Surgery; Systematic Reviews as T

2023
Efficacy and safety of single- and double-dose intravenous tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2023, Aug-10, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2023, Aug-29, Volume: 24, Issue:1

    Topics: Adolescent; Blood Loss, Surgical; Exsanguination; Humans; Orthopedic Procedures; Scoliosis; Tranexam

2023
Systematic review and meta-analysis of topical tranexamic acid in spine surgery.
    Neurosurgical focus, 2023, Volume: 55, Issue:4

    Topics: Blood Loss, Surgical; Case-Control Studies; Cross-Sectional Studies; Hemoglobins; Humans; Postoperat

2023
Does tranexamic acid diminish hemorrhage and pain in open elbow arthrolysis? a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2023, Oct-06, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Elbow; Humans; Pain; Postoperative Hemorrhage; Tranex

2023
Tranexamic acid versus misoprostol for management of postpartum hemorrhage: A systematic review and meta-analysis of randomized controlled trials.
    European journal of obstetrics, gynecology, and reproductive biology, 2023, Volume: 291

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemostatics; Humans; Misoprostol; Postpartum

2023
Effects of intraoperative or postoperative administration of intravenous iron supplements on hemoglobin recovery in patients with total knee arthroplasty: A systematic review and meta-analysis.
    Medicine, 2023, Oct-27, Volume: 102, Issue:43

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Efficacy and safety of tranexamic acid in prevention of postpartum hemorrhage: a systematic review and meta-analysis of 18,649 patients.
    BMC pregnancy and childbirth, 2023, Nov-24, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemoglobins; Humans; Nausea; Postpartum Hemor

2023
Comparison of efficacy between tranexamic acid and epsilon-aminocaproic acid for total knee arthroplasty: A meta-analysis of randomized controlled trials.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
The Safety and Efficacy of Tranexamic Acid in Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis.
    Drugs, 2019, Volume: 79, Issue:15

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Spinal Curvatures; Tranexamic Acid

2019
Intravenous tranexamic acid reduces blood transfusions in revision total hip arthroplasty: a meta-analysis.
    Journal of comparative effectiveness research, 2019, Volume: 8, Issue:11

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2019
Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures.
    Journal of cardiothoracic and vascular anesthesia, 2020, Volume: 34, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Cardi

2020
Efficacy and Safety of Tranexamic Acid in Reducing Blood Loss of Lower Extremity Osteotomy in Peri-acetabulum and High Tibia: A Systematic Review and Meta-analysis.
    Orthopaedic surgery, 2019, Volume: 11, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Lower Extremity; Osteotomy

2019
Efficacy and safety of tranexamic acid usage in patients undergoing posterior lumbar fusion: a meta-analysis.
    BMC musculoskeletal disorders, 2019, Aug-31, Volume: 20, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Humans; Intervertebra

2019
Hemostatic techniques to reduce blood transfusion after primary TKA: a meta-analysis and systematic review.
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:12

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2019
Reducing blood loss in pediatric craniosynostosis surgery by use of tranexamic acid.
    Neuro-Chirurgie, 2019, Volume: 65, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2019
Tranexamic Acid in the Perioperative Period: Yes, No, Maybe?
    Advances in anesthesia, 2019, Volume: 37

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Dose-Response Relationship, Drug; Humans; Postoperati

2019
Incidence of Thromboembolic Events in Oncology Patients Receiving Intraoperative Tranexamic Acid During Orthopedic Surgery: A Retrospective Review at a Comprehensive Cancer Center.
    A&A practice, 2020, Jan-15, Volume: 14, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Incidence; Intraoperativ

2020
The efficiency and safety of oral tranexamic acid in total hip arthroplasty: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:46

    Topics: Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical;

2019
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.
    European journal of haematology, 2020, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Menorrhagia; Postpartum Hemorrh

2020
Topical Tranexamic Acid Is Effective in Cementless Total Knee Arthroplasty.
    The Orthopedic clinics of North America, 2020, Volume: 51, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2020
Efficacy and Safety of Tranexamic Acid Combined with Rivaroxaban in Primary Total Knee Arthroplasty: A Meta-Analysis of Randomized Controlled Trials.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2021, Volume: 34, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Randomized C

2021
Efficacy and safety of tranexamic acid in orthopaedic trauma surgery: a meta-analysis.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:24

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Orthopedic Procedures; Tra

2019
Tranexamic acid in gynecologic surgery.
    Current medical research and opinion, 2020, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Femal

2020
The efficacy and safety of tranexamic acid in the treatment of intertrochanteric fracture: an updated meta-analysis of 11 randomized controlled trials.
    Journal of thrombosis and thrombolysis, 2020, Volume: 50, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation; Hip Fractures; Human

2020
Postoperative outcomes of tranexamic acid use in geriatric trauma patients treated with proximal femoral intramedullary nails: A systematic review and meta-analysis.
    Orthopaedics & traumatology, surgery & research : OTSR, 2020, Volume: 106, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2020
Advances in surgical hemostasis: a comprehensive review and meta-analysis on topical tranexamic acid in spinal deformity surgery.
    Neurosurgical review, 2021, Volume: 44, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostatic Techniques; Human

2021
Comparison of efficacy and safety between oral and intravenous administration of tranexamic acid for primary total knee/hip replacement: a meta-analysis of randomized controlled trial.
    Journal of orthopaedic surgery and research, 2020, Jan-20, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2020
[Fast-track arthroplasty-intra- and post-operative management].
    Der Orthopade, 2020, Volume: 49, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; I

2020
Efficacy and Safety of Tranexamic Acid in Major Non-Cardiac Surgeries at High Risk for Transfusion: A Systematic Review and Meta-Analysis.
    Transfusion medicine reviews, 2020, Volume: 34, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Male; Risk

2020
Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2).
    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2020, Volume: 4, Issue:1

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgi

2020
Efficacy and safety of tranexamic acid for reducing blood loss in elderly patients with intertrochanteric fracture treated with intramedullary fixation surgery: A meta-analysis of randomized controlled trials.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2020
Comparison of Intravenous versus Topical Tranexamic Acid in Nondeformity Spine Surgery: A Meta-Analysis.
    BioMed research international, 2020, Volume: 2020

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Datab

2020
A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss: A Meta-analysis.
    Annals of surgery, 2021, 01-01, Volume: 273, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Preoperative Care; Tranexamic Acid

2021
A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss: A Meta-analysis.
    Annals of surgery, 2021, 01-01, Volume: 273, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Preoperative Care; Tranexamic Acid

2021
A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss: A Meta-analysis.
    Annals of surgery, 2021, 01-01, Volume: 273, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Preoperative Care; Tranexamic Acid

2021
A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss: A Meta-analysis.
    Annals of surgery, 2021, 01-01, Volume: 273, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Preoperative Care; Tranexamic Acid

2021
Prophylactic Topical Tranexamic Acid Versus Placebo in Surgical Patients: A Systematic Review and Meta-analysis∗.
    Annals of surgery, 2021, 04-01, Volume: 273, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorr

2021
Utility of Tranexamic acid to minimize blood loss in brain tumour surgery.
    JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Brain Neoplasms; Humans; Neurosurgical Procedures; Tr

2020
Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2020, Mar-31, Volume: 35, Issue:1

    Topics: Adult; Aged; Blood Loss, Surgical; Female; Humans; Male; Middle Aged; Myocardial Infarction; Risk Fa

2020
The never ending success story of tranexamic acid in acquired bleeding.
    Haematologica, 2020, Volume: 105, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Thromboembolism; Tranexami

2020
Effectiveness and safety of the use of antifibrinolytic agents in total-knee arthroplasty: A meta-analysis.
    Medicine, 2020, Volume: 99, Issue:20

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2020
Tranexamic acid in Neurosurgery: a controversy indication-review.
    Neurosurgical review, 2021, Volume: 44, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Brain Injuries, Traumatic;

2021
Efficacy and safety of the tranexamic acid in reducing blood loss and transfusion requirements during percutaneous nephrolithotomy: a systematic review and meta-analysis of randomized controlled trials.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2020, Volume: 72, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Nephrolithotomy, Percutane

2020
The effect of tranexamic acid on the values of activated clotting time in patients undergoing cardiac surgery: A PRISMA-compliant systematic review and meta-analysis.
    Journal of clinical anesthesia, 2020, Volume: 67

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Postoperative He

2020
The optimal regimen of oral tranexamic acid administration for primary total knee/hip replacement: a meta-analysis and narrative review of a randomized controlled trial.
    Journal of orthopaedic surgery and research, 2020, Oct-06, Volume: 15, Issue:1

    Topics: Administration, Oral; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Hemostatic effect of tourniquet combined with tranexamic acid in total knee arthroplasty: a network meta-analysis.
    Journal of orthopaedic surgery and research, 2020, Nov-12, Volume: 15, Issue:1

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control S

2020
Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Dec-02, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Dec-02, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Dec-02, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Dec-02, Volume: 15, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Exposure-Response Relationship of Tranexamic Acid in Cardiac Surgery.
    Anesthesiology, 2021, 02-01, Volume: 134, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Dose-Response Relationsh

2021
Tranexamic Acid in Foot and Ankle Surgery: A Topical Review and Value Analysis.
    Foot & ankle specialist, 2022, Volume: 15, Issue:4

    Topics: Ankle; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Trane

2022
The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis.
    Journal of orthopaedic surgery and research, 2021, Jan-14, Volume: 16, Issue:1

    Topics: Adolescent; Blood Loss, Surgical; Female; Humans; Infusions, Intravenous; Intraoperative Complicatio

2021
What is the ideal route of administration of tranexamic acid in total knee arthroplasty? A meta-analysis based on randomized controlled trials.
    Annals of palliative medicine, 2021, Volume: 10, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Randomized C

2021
Different Dose Regimens of Intravenous Tranexamic Acid in Adolescent Spinal Deformity Surgery: A Systematic Review and Meta-Analysis.
    BioMed research international, 2020, Volume: 2020

    Topics: Administration, Intravenous; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood

2020
Role of tranexamic acid in blood loss control and blood transfusion management of patients undergoing multilevel spine surgery: A meta-analysis.
    Medicine, 2021, Feb-19, Volume: 100, Issue:7

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Case-Cont

2021
[Tranexamic acid for bleeding prophylaxis in orthopedic surgery and trauma-standard or customized therapy?]
    Der Anaesthesist, 2021, Volume: 70, Issue:6

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Loss, Surgical; Hemorrhage; Humans; Orth

2021
Comparative efficacy and safety of topical hemostatic agents in primary total knee arthroplasty: A network meta-analysis of randomized controlled trials.
    Medicine, 2021, Mar-26, Volume: 100, Issue:12

    Topics: Administration, Topical; Adult; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2021
The Use of Tranexamic Acid in Hip and Pelvic Fracture Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2021, Jun-15, Volume: 29, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Tranexamic

2021
Assessment of Tranexamic Acid in Reducing Intraoperative Blood Loss During Rhytidectomy.
    The Laryngoscope, 2022, Volume: 132, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Practice Guidelines as Topic; Rhytidoplasty;

2022
Safety and efficacy of tranexamic acid in minimizing perioperative bleeding in extrahepatic abdominal surgery: meta-analysis.
    BJS open, 2021, 03-05, Volume: 5, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Perioperative Care; Randomized Controlled Tri

2021
Antifibrinolytics reduces blood loss in thoracic surgery: a systematic review and meta-analysis.
    ANZ journal of surgery, 2021, Volume: 91, Issue:6

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Humans; Thoracic Surgery; Tranexamic Acid

2021
Tranexamic acid: current use in obstetrics, major orthopedic, and trauma surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021, Volume: 68, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemorrhage; Humans; Obstetrics; Tr

2021
A Meta-Analysis of Complications of Tranexamic Acid Use in Lower-Limb Orthopedic Surgery.
    AORN journal, 2021, Volume: 113, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthopedic Procedures; Orthopedics; Tranexami

2021
Blood Management in Outpatient Total Hip Arthroplasty.
    The Orthopedic clinics of North America, 2021, Volume: 52, Issue:3

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip

2021
The efficacy and safety of tranexamic acid in high tibial osteotomy: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2021, Jun-11, Volume: 16, Issue:1

    Topics: Blood Loss, Surgical; Female; Hemoglobins; Humans; Male; Osteotomy; Postoperative Complications; Saf

2021
Tranexamic acid given into wound reduces postoperative drainage, blood loss, and hospital stay in spinal surgeries: a meta-analysis.
    Journal of orthopaedic surgery and research, 2021, Jun-22, Volume: 16, Issue:1

    Topics: Administration, Topical; Blood Loss, Surgical; Clinical Trials as Topic; Drainage; Humans; Length of

2021
Efficacy and Safety of Antifibrinolytic Drugs in Pediatric Surgery: A Systematic Review.
    Seminars in thrombosis and hemostasis, 2021, Volume: 47, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Humans; Pharmaceutical Prep

2021
The Efficacy and Safety of Topical Tranexamic Acid for Spinal Surgery.
    Current pharmaceutical design, 2021, Volume: 27, Issue:44

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; T

2021
Comparison of intravenous versus topical tranexamic acid in primary total hip and knee arthroplasty: An updated meta-analysis.
    Thrombosis research, 2017, Volume: 153

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
A comparison of combined intravenous and topical administration of tranexamic acid with intravenous tranexamic acid alone for blood loss reduction after total hip arthroplasty: A meta-analysis.
    International journal of surgery (London, England), 2017, Volume: 41

    Topics: Administration, Cutaneous; Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Repla

2017
Preventing perioperative bleeding in patients with inherited bleeding disorders.
    Evidence-based dentistry, 2017, Volume: 18, Issue:1

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Hemophilia A; Humans; Postoperativ

2017
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.
    Transfusion medicine reviews, 2017, Volume: 31, Issue:3

    Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans;

2017
Intra-articular versus intravenous tranexamic acid application in total knee arthroplasty: a meta-analysis of randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2017, Volume: 137, Issue:7

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2017
Intra-articular Tranexamic Acid in Primary Total Knee Arthroplasty: Meta-analysis.
    The journal of knee surgery, 2018, Volume: 31, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2018
Is combined use of intravenous and intraarticular tranexamic acid superior to intravenous or intraarticular tranexamic acid alone in total knee arthroplasty? A meta-analysis of randomized controlled trials.
    Journal of orthopaedic surgery and research, 2017, Apr-18, Volume: 12, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2017
Tranexamic acid reduces blood loss and transfusion requirements in primary simultaneous bilateral total knee arthroplasty: a meta-analysis of randomized controlled trials.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2017, Volume: 28, Issue:7

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Humans; Middle Aged;

2017
Indications for and complications of transfusion and the management of gynecologic malignancies.
    Gynecologic oncology, 2017, Volume: 146, Issue:2

    Topics: Acute Lung Injury; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Transfusion; F

2017
Is combined topical and intravenous tranexamic acid superior to intravenous tranexamic acid alone for controlling blood loss after total hip arthroplasty?: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:21

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Efficacy and safety of intravenous tranexamic acid administration in patients undergoing hip fracture surgery for hemostasis: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:21

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Fractures; Humans; Orthopedic

2017
Efficiency and safety of tranexamic acid in reducing blood loss in total shoulder arthroplasty: A systematic review and meta-analysis.
    Medicine, 2017, Volume: 96, Issue:22

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Transfusio

2017
The efficiency and safety of tranexamic acid for reducing blood loss in open myomectomy: A meta-analysis of randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:23

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Randomized Controlled Trials as Topic

2017
Combined versus single application of tranexamic acid in total knee and hip arthroplasty: A meta-analysis of randomized controlled trials.
    International journal of surgery (London, England), 2017, Volume: 43

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2017
Tranexamic acid plus diluted-epinephrine versus tranexamic acid alone for blood loss in total joint arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:24

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Drug Therapy, Combination;

2017
The efficacy and safety of tranexamic acid in revision total knee arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2017, Jun-21, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Length of St

2017
Efficacy of tranexamic acid plus drain-clamping to reduce blood loss in total knee arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:26

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Clinical Studies as

2017
Tranexamic Acid in Total Knee Arthroplasty: Mixed Treatment Comparisons and Recursive Cumulative Meta-Analysis of Randomized, Controlled Trials and Cohort Studies.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Antifibrinolytic Agents;

2018
Desmopressin use for minimising perioperative blood transfusion.
    The Cochrane database of systematic reviews, 2017, 07-10, Volume: 7

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Deamin

2017
Is combined topical and intravenous tranexamic acid superior to single use of tranexamic acid in total joint arthroplasty?: A meta-analysis from randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:30

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2017
Comparison of oral versus intravenous application of tranexamic acid in total knee and hip arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2017, Volume: 45

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2017
Tranexamic acid decreases blood loss in shoulder arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:33

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Tran

2017
Most Effective Regimen of Tranexamic Acid for Reducing Bleeding and Transfusions in Primary Total Knee Arthroplasty: A Meta-Analysis of Randomized Controlled Trials.
    The journal of knee surgery, 2018, Volume: 31, Issue:7

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2018
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
Tranexamic Acid in Shoulder Arthroplasty: A Systematic Review and Meta-Analysis.
    JBJS reviews, 2017, Volume: 5, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2017
The efficacy of tranexamic acid in reducing blood loss in total shoulder arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:37

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Humans; Tranexam

2017
Tranexamic Acid in Orthopaedic Trauma Surgery: A Meta-Analysis.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Female; Humans; Male; Orthopedi

2017
Efficacy and Safety of Tranexamic Acid in Orthopaedic Fracture Surgery: A Meta-Analysis and Systematic Literature Review.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Fracture Fixation; Fractur

2017
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
Effect of tranexamic acid use on blood loss and thromboembolic risk in hip fracture surgery: systematic review and meta-analysis.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Hip Fractures; Humans

2018
A systematic review and meta-analysis comparing combined intravenous and topical tranexamic acid with intravenous administration alone in THA.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
The efficacy of combined intra-articular and intravenous tranexamic acid for blood loss in primary total knee arthroplasty: A meta-analysis.
    Medicine, 2017, Volume: 96, Issue:42

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
The efficacy of tranexamic acid using oral administration in total knee arthroplasty: a systematic review and meta-analysis.
    Journal of orthopaedic surgery and research, 2017, Oct-27, Volume: 12, Issue:1

    Topics: Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical

2017
The effect of tranexamic acid to reduce blood loss and transfusion on off-pump coronary artery bypass surgery: A systematic review and cumulative meta-analysis.
    Journal of clinical anesthesia, 2018, Volume: 44

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass, Off-Pump;

2018
Antifibrinolytic Therapy and Perioperative Considerations.
    Anesthesiology, 2018, Volume: 128, Issue:3

    Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Loss, Surgical; Fibrinolysis; Humans; Pe

2018
Can tranexamic acid conserve blood and save operative time in spinal surgeries? A meta-analysis.
    The spine journal : official journal of the North American Spine Society, 2018, Volume: 18, Issue:8

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Neurosurgical Pr

2018
Tranexamic Acid Prophylaxis in Hip and Knee Joint Replacement.
    Deutsches Arzteblatt international, 2017, 12-01, Volume: 114, Issue:48

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2017
[Research progress on tranexamic acid application strategy in total knee arthroplasty].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2016, Oct-25, Volume: 29, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2016
Safety of intravenous tranexamic acid in patients undergoing majororthopaedic surgery: a meta-analysis of randomised controlled trials.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:1

    Topics: Administration, Intravenous; Blood Loss, Surgical; Female; Humans; Male; Orthopedic Procedures; Rand

2018
[Prophylactic use of tranexamic acid in noncardiac surgery : Update 2017].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019, Volume: 114, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Intraoperative Care; Male; Tranexamic

2019
Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:52

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hip Fractures; Humans; R

2017
Efficacy and safety of tranexamic acid in total hip replacement: A PRISMA-compliant meta-analysis of 25 randomized controlled trials.
    Medicine, 2017, Volume: 96, Issue:52

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Tranexamic acid plus drain-clamping can reduce blood loss in total knee arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2018, Volume: 52

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2018
[Blood management in complex reconstructive spine surgery in ASD patients : Do effective measures to reduce bleeding exist?]
    Der Orthopade, 2018, Volume: 47, Issue:4

    Topics: Blood Loss, Surgical; Drainage; Hemostatics; Humans; Male; Spine; Tranexamic Acid

2018
Tranexamic acid in total shoulder arthroplasty and reverse shoulder arthroplasty: a systematic review and meta-analysis.
    BMC musculoskeletal disorders, 2018, 02-17, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Transfusio

2018
The efficacy and safety of topical administration of tranexamic acid in spine surgery: a meta-analysis.
    Journal of orthopaedic surgery and research, 2018, Apr-24, Volume: 13, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Length of Stay; Rand

2018
The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Thromboembolism; T

2018
The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Thromboembolism; T

2018
The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Thromboembolism; T

2018
The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Thromboembolism; T

2018
Efficacy and safety of oral tranexamic acid in total knee arthroplasty: A systematic review and meta-analysis.
    Medicine, 2018, Volume: 97, Issue:18

    Topics: Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical

2018
Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: A systematic review and meta-analysis.
    International journal of surgery (London, England), 2018, Volume: 54, Issue:Pt A

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
Systematic review and meta-analyses of tranexamic acid use for bleeding reduction in prostate surgery.
    Journal of clinical anesthesia, 2018, Volume: 48

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Incidence; Male; Prostatec

2018
Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty: A Meta-Analysis.
    JBJS reviews, 2018, Volume: 6, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2018
Safety and efficacy of tranexamic acid for prevention of obstetric haemorrhage: an updated systematic review and meta-analysis.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:4

    Topics: Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; PubMed; Randomized Controlled Tri

2018
The Efficacy of Tranexamic Acid in Total Knee Arthroplasty: A Network Meta-Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans; Netw

2018
The Efficacy of Tranexamic Acid in Total Hip Arthroplasty: A Network Meta-analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2018
The Efficacy of Tranexamic Acid on Blood Loss from Lumbar Spinal Fusion Surgery: A Meta-Analysis of Randomized Controlled Trials.
    World neurosurgery, 2018, Volume: 119

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Databases, Bibliographic; Female; Humans; Male; Rando

2018
Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis.
    JAMA otolaryngology-- head & neck surgery, 2018, 09-01, Volume: 144, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Schedule; Ecchymosis; Edema; Eyel

2018
The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials.
    BMC musculoskeletal disorders, 2018, Sep-07, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Is the combined application of both drain-clamping and tranexamic acid superior to the single use of either application in patients with total-knee arthroplasty?: A meta-analysis of randomized controlled trials.
    Medicine, 2018, Volume: 97, Issue:36

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Combined Modality Th

2018
The efficacy of oral versus intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: A meta-analysis.
    Medicine, 2018, Volume: 97, Issue:36

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthritis; Arthroplasty,

2018
A systematic review of tranexamic acid usage in patients undergoing femoral fracture surgery.
    Clinical interventions in aging, 2018, Volume: 13

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical;

2018
Comparative effectiveness and safety of tranexamic acid plus diluted epinephrine to control blood loss during total hip arthroplasty: a meta-analysis.
    Journal of orthopaedic surgery and research, 2018, Sep-21, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Co

2018
The Efficacy and Safety of Intravenous Tranexamic Acid in Reducing Surgical Blood Loss in Posterior Lumbar Interbody Fusion for the Adult: A Systematic Review and a Meta-Analysis.
    World neurosurgery, 2019, Volume: 122

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Human

2019
Use of antifibrinolytics in pediatric cardiac surgery: Where are we now?
    Paediatric anaesthesia, 2019, Volume: 29, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2019
Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Network Meta-

2018
The Effectiveness of Tranexamic Acid at Reducing Blood Loss and Transfusion Requirement for Women Undergoing Myomectomy: A Systematic Review and Meta-analysis.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2019, Volume: 41, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Leiomyoma;

2019
Tranexamic Acid Decreases Blood Transfusion Burden in Open Craniosynostosis Surgery Without Operative Compromise.
    The Journal of craniofacial surgery, 2019, Volume: 30, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Craniosynostoses; Erythrocyte Transfusion; Humans; In

2019
Tranexamic Acid Plus Low-dose Epinephrine Reduces Blood Loss in Total Knee Arthroplasty: A Systematic Review and Meta-analysis.
    Orthopaedic surgery, 2018, Volume: 10, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; D

2018
Oral tranexamic acid reduces blood loss in total-knee arthroplasty: A meta-analysis.
    Medicine, 2018, Volume: 97, Issue:45

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2018
Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2018, Dec-03, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2018
Exclusion criteria and adverse events in perioperative trials of tranexamic acid: a systematic review and meta-analysis.
    Transfusion, 2019, Volume: 59, Issue:2

    Topics: Blood Loss, Surgical; Blood Transfusion; Drug Hypersensitivity; Humans; Randomized Controlled Trials

2019
Efficacy of tranexamic acid on operative bleeding in endoscopic sinus surgery: A meta-analysis and systematic review.
    The Laryngoscope, 2019, Volume: 129, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Female; Humans; Incidence; Male; Mi

2019
Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis.
    JAMA facial plastic surgery, 2019, May-01, Volume: 21, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Humans; Postoperative Complication

2019
Comparative efficacy and safety of different hemostatic methods in total hip arthroplasty: a network meta-analysis.
    Journal of orthopaedic surgery and research, 2019, Jan-04, Volume: 14, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemostatic Techniques

2019
Is intravenous tranexamic acid effective and safe during hip fracture surgery? An updated meta-analysis of randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:7

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Fract

2019
Effectiveness and safety of tranexamic acid in total joint arthroplasty.
    Journal of perioperative practice, 2019, Volume: 29, Issue:11

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2019
[Perioperative care of epithelial ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF a
    Gynecologie, obstetrique, fertilite & senologie, 2019, Volume: 47, Issue:2

    Topics: Analgesia, Patient-Controlled; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Carcinoma, Ova

2019
Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials.
    BMJ open, 2019, 01-28, Volume: 9, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Anemia; Antifibrinolytic Agents; Arthroplasty,

2019
The Use of Tranexamic Acid to Reduce Surgical Blood Loss: A Review Basic Science, Subspecialty Studies, and The Evolution of Use in Spine Deformity Surgery.
    Clinical spine surgery, 2019, Volume: 32, Issue:2

    Topics: Arthroplasty; Blood Loss, Surgical; Dose-Response Relationship, Drug; Humans; Spine; Tranexamic Acid

2019
The Role of Antifibrinolytics in Reducing Blood Loss During Craniofacial or Orthognathic Surgical Procedures: A Meta-Analysis.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2019, Volume: 77, Issue:6

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Denmark; Humans; Ort

2019
Comprehensive assessment of tranexamic acid during orthognathic surgery: A systematic review and meta-analysis of randomized, controlled trials.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2019, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Orthognathic Surgery; Rand

2019
Comparison between oral and intravenous application of tranexamic acid for total hip arthroplasty: a meta-analysis.
    Journal of comparative effectiveness research, 2019, Volume: 8, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2019
Does Tranexamic Acid Improve Bleeding, Transfusion, and Hemoglobin Level in Patients Undergoing Multilevel Spine Surgery? A Systematic Review and Meta-Analysis.
    World neurosurgery, 2019, Volume: 127

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Humans; Postoperative

2019
Tranexamic acid can reduce blood loss in patients undergoing intertrochanteric fracture surgery: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hematoma; Hemoglobins; Hip Fractur

2019
Tranexamic acid and perioperative bleeding in children: what do we still need to know?
    Current opinion in anaesthesiology, 2019, Volume: 32, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response Relationship,

2019
The efficacy of tranexamic acid for orthognathic surgery: a meta-analysis of randomized controlled trials.
    International journal of oral and maxillofacial surgery, 2019, Volume: 48, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthognathic Surgery; Randomized Controlled T

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Applications of Tranexamic acid in benign gynecology.
    Current opinion in obstetrics & gynecology, 2019, Volume: 31, Issue:4

    Topics: Administration, Oral; Blood Loss, Surgical; Female; Gynecologic Surgical Procedures; Humans; Infusio

2019
Transfusions and cost-benefit of oral versus intravenous tranexamic acid in primary total hip arthroplasty: A meta-analysis of randomized controlled trials.
    Medicine, 2019, Volume: 98, Issue:17

    Topics: Administration, Intravenous; Administration, Oral; Antifibrinolytic Agents; Arthroplasty, Replacemen

2019
Oral vs intravenous tranexamic acid in total-knee arthroplasty and total hip arthroplasty: A systematic review and meta-analysis.
    Medicine, 2019, Volume: 98, Issue:20

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Antifibrinolytic

2019
Exclusion criteria and adverse events in perioperative trials of tranexamic acid in cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2019, Volume: 66, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Eligi

2019
The Perioperative Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Scoliosis.
    World neurosurgery, 2019, Volume: 129

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Scoliosis; Spinal F

2019
Prophylactic use of tranexamic acid reduces blood loss and transfusion requirements in patients undergoing cesarean section: A meta-analysis.
    The journal of obstetrics and gynaecology research, 2019, Volume: 45, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cesarean Section; Female; Humans;

2019
Management of the patient presenting with anaemia in the preoperative setting.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2019, Volume: 58, Issue:4

    Topics: Anemia; Blood Loss, Surgical; Erythrocyte Transfusion; Humans; Operative Blood Salvage; Preoperative

2019
Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study.
    Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2019, Jul-18, Volume: 20, Issue:1

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; B

2019
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2012, Volume: 12

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo

2012
Tranexamic acid for reducing mortality in emergency and urgent surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Emergencies; Humans; Random

2013
Tranexamic acid for reducing mortality in emergency and urgent surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Emergencies; Humans; Random

2013
Tranexamic acid for reducing mortality in emergency and urgent surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Emergencies; Humans; Random

2013
Tranexamic acid for reducing mortality in emergency and urgent surgery.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Emergencies; Humans; Random

2013
Use of intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2013, Volume: 16, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2013
Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014, Volume: 22, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Dose-Response Relati

2014
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2013, Volume: 133, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Postoperative

2013
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2013, Volume: 133, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Postoperative

2013
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2013, Volume: 133, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Postoperative

2013
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials.
    Archives of orthopaedic and trauma surgery, 2013, Volume: 133, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Postoperative

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.
    BMC research notes, 2013, May-07, Volume: 6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Is tranexamic acid effective and safe in spinal surgery? A meta-analysis of randomized controlled trials.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Randomized Controlled Trials as T

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Antifibrinolytic agents in current anaesthetic practice.
    British journal of anaesthesia, 2013, Volume: 111, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Knee, 2013, Volume: 20, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss.
    The British journal of surgery, 2013, Volume: 100, Issue:10

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Dose-Response Relationship, Drug; Humans; Rand

2013
[Perioperative management of type 2B Von Willebrand's disease in a patient undergoing urgent abdominal surgery].
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:4

    Topics: Abdomen, Acute; Blood Loss, Surgical; Emergencies; Factor VIII; Female; Heparin, Low-Molecular-Weigh

2014
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
Topical application of tranexamic acid for the reduction of bleeding.
    The Cochrane database of systematic reviews, 2013, Jul-23, Issue:7

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epistaxis; Hemorrhage; Human

2013
[Hemostasis and antifibrinolytic therapy in major pediatric surgery].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2013, Volume: 48, Issue:7-8

    Topics: Adolescent; Age Factors; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical

2013
[Current strategies to minimize of blood loss during radical prostatectomy].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2013, Volume: 48, Issue:7-8

    Topics: Adult; Aged; Anesthesia, Epidural; Antifibrinolytic Agents; Blood Loss, Surgical; Fibrinolysis; Flui

2013
The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis.
    The Journal of surgical research, 2014, Volume: 186, Issue:1

    Topics: Anti-Arrhythmia Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Humans; Orthopedic Pr

2014
Role of tranexamic acid in endoscopic sinus surgery - a systematic review and meta-analysis.
    Rhinology, 2013, Volume: 51, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Humans; Paranasal Sinuses; Tranexamic Acid

2013
Interventions for preventing blood loss during the treatment of cervical intraepithelial neoplasia.
    The Cochrane database of systematic reviews, 2013, Dec-04, Issue:12

    Topics: Blood Loss, Surgical; Female; Ferric Compounds; Hemostasis, Surgical; Hemostatics; Humans; Inositol;

2013
Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014, Volume: 22, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2014
The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis.
    Transfusion medicine reviews, 2014, Volume: 28, Issue:3

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Gynecologic Surgical Procedures; Hemorrh

2014
Safety and efficacy of intra-articular injection of tranexamic acid in total knee arthroplasty.
    Orthopedics, 2014, Volume: 37, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2014
Is tranexamic acid clinically effective and safe to prevent blood loss in total knee arthroplasty? A meta-analysis of 34 randomized controlled trials.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
The current place of tranexamic acid in the management of bleeding.
    Anaesthesia, 2015, Volume: 70 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Postpartum Hemorrhage; Thrombosis

2015
A systematic review of the effectiveness of intravenous tranexamic acid administration in managing perioperative blood loss in patients undergoing spine surgery.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2014, Volume: 29, Issue:6

    Topics: Blood Loss, Surgical; Humans; Infusions, Intravenous; Orthopedic Procedures; Spine; Tranexamic Acid

2014
Effectiveness of tranexamic acid in reducing blood loss in spinal surgery: a meta-analysis.
    BMC musculoskeletal disorders, 2014, Dec-22, Volume: 15

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Neurosurgical Procedures; Randomized Controll

2014
Efficiency of tranexamic acid in perioperative blood loss in hip arthroplasty: a systematic literature review and meta-analysis.
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Female;

2015
Efficacy of tranexamic acid on surgical bleeding in spine surgery: a meta-analysis.
    The spine journal : official journal of the North American Spine Society, 2015, Apr-01, Volume: 15, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthopedic Procedures; Spine; Tranexamic Acid

2015
One step closer to sparing total blood loss and transfusion rate in total knee arthroplasty: a meta-analysis of different methods of tranexamic acid administration.
    Archives of orthopaedic and trauma surgery, 2015, Volume: 135, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Tranexamic acid: a clinical review.
    Anaesthesiology intensive therapy, 2015, Volume: 47, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; General Surgery; Humans; Tranexamic Acid

2015
Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery.
    The Cochrane database of systematic reviews, 2015, Feb-09, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor VIIa; Hemophilia A; Hemophi

2015
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2015, May-09, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo

2015
Effect of Topical Tranexamic Acid in Reducing Bleeding and Transfusions in TKA.
    Orthopedics, 2015, Volume: 38, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2015
What dose of tranexamic acid is most effective and safe for adult patients undergoing cardiac surgery?
    Interactive cardiovascular and thoracic surgery, 2015, Volume: 21, Issue:3

    Topics: Adult; Angina, Unstable; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Dose

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases.
    Transfusion medicine (Oxford, England), 2015, Volume: 25, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Human

2015
Prevention of Bleeding in Orthognathic Surgery--A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:1

    Topics: Blood Loss, Surgical; Hematocrit; Hemoglobins; Hemostatics; Humans; Operative Time; Orthognathic Sur

2016
[The possibility of using tranexamic acid for the treatment of bleeding in otorhinolaryngology].
    Vestnik otorinolaringologii, 2015, Volume: 80, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Otorhinolaryngologic Surgical Procedures; Pos

2015
Techniques to reduce blood loss during open myomectomy: a qualitative review of literature.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 192

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Gonadotropin-Releasing Hormone; Hemostasis, S

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Tranexamic acid and blood loss during and after cesarean section: a meta-analysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cesarean Section; Fe

2015
Exploring redundant research into the effect of tranexamic acid on surgical bleeding: further analysis of a systematic review of randomised controlled trials.
    BMJ open, 2015, Aug-24, Volume: 5, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; Resear

2015
Predicting Blood Loss in Total Knee and Hip Arthroplasty.
    The Orthopedic clinics of North America, 2015, Volume: 46, Issue:4

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2015
Safety and Efficacy of Tranexamic Acid in Total Knee Arthroplasty.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Oct-14, Volume: 21

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; D

2015
[PERIOPERATIVE BLOOD MANAGEMENT STRATEGIES FOR JOINT ARTHROPLASTY].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2015, Volume: 29, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, A

2015
Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2015, Volume: 23, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2015
Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2015, Volume: 23, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2015
Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2015, Volume: 23, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2015
Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2015, Volume: 23, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2015
Blood Loss and Transfusion After Topical Tranexamic Acid Administration in Primary Total Knee Arthroplasty.
    Orthopedics, 2015, Volume: 38, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2015
Prevention of post-operative anaemia in hip and knee arthroplasty--a systematic review.
    Danish medical journal, 2015, Volume: 62, Issue:12

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, K

2015
Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.
    The Cochrane database of systematic reviews, 2015, Dec-24, Issue:12

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor IX; Factor VIII; Hemophilia

2015
Effectiveness of tranexamic acid in reducing blood loss during cytoreductive surgery for advanced ovarian cancer.
    The Cochrane database of systematic reviews, 2016, Jan-23, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cytoreduction Surgical Proc

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, Feb-16, Volume: 17

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Diagnosis, prevention, and management of bleeding episodes in Philadelphia-negative myeloproliferative neoplasms: recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO) and the Society of Thrombosis
    Annals of hematology, 2016, Volume: 95, Issue:5

    Topics: Anticoagulants; Antineoplastic Agents; Blood Coagulation Factors; Blood Loss, Surgical; Blood Transf

2016
The Efficacy and Safety of Tranexamic Acid in Cranio-Maxillofacial and Plastic Surgery.
    The Journal of craniofacial surgery, 2016, Volume: 27, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Face; Facial Bones; Humans; Micros

2016
Manifestation of tranexamic acid toxicity in chronic kidney disease and kidney transplant patients: A report of four cases and review of literature.
    Nephrology (Carlton, Vic.), 2017, Volume: 22, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Blood Loss, Surgic

2017
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.
    Orthopedics, 2016, Sep-01, Volume: 39, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2016
Intravenous versus topical tranexamic acid in primary total hip replacement: A systemic review and meta-analysis.
    International journal of surgery (London, England), 2016, Volume: 32

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Comparison of efficacy and safety of topical versus intravenous tranexamic acid in total hip arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:36

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Efficiency and Safety of Intravenous Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Systematic Review and Meta-analysis.
    Orthopaedic surgery, 2016, Volume: 8, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2016
Topical versus intravenous tranexamic acid in total knee arthroplasty: a meta-analysis of randomized controlled trials.
    International orthopaedics, 2017, Volume: 41, Issue:4

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2017
Combined intravenous and topical tranexamic acid versus intravenous use alone in primary total knee and hip arthroplasty: A meta-analysis of randomized controlled trials.
    International journal of surgery (London, England), 2016, Volume: 36, Issue:Pt A

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2016
Efficacy and safety of tranexamic acid in reducing blood loss in scoliosis surgery: a systematic review and meta-analysis.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017, Volume: 26, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Postoperative Hemorrhage; Scolio

2017
Combined use of intravenous and topical versus intravenous tranexamic acid in primary total joint arthroplasty: A meta-analysis of randomized controlled trials.
    International journal of surgery (London, England), 2017, Volume: 38

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:50

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Comparing efficacy and safety of 2 methods of tranexamic acid administration in reducing blood loss following total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:50

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:51

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:51

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:51

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty: A meta-analysis.
    Medicine, 2016, Volume: 95, Issue:51

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
A systematic review and meta-analysis of the effect of prophylactic tranexamic acid treatment in major benign uterine surgery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2017, Volume: 136, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cesarean Section; Female; Gynecolo

2017
Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials.
    Journal of orthopaedic surgery and research, 2017, Jan-19, Volume: 12, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Combined use of intravenous and topical versus intravenous tranexamic acid in primary total knee and hip arthroplasty: a meta-analysis of randomised controlled trials.
    Journal of orthopaedic surgery and research, 2017, Feb-02, Volume: 12, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2017, 02-21, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Arthroplasty, Replacement, Hip; Blood Loss, Su

2017
Seizures associated with tranexamic acid for cardiac surgery: a meta-analysis of randomized and non-randomized studies.
    The Journal of cardiovascular surgery, 2017, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac S

2017
[Blood conservation approaches in orthopedic surgery].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2008, Volume: 15, Issue:5

    Topics: Anemia; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Autologous; Drug Admi

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The use of antifibrinolytic agents in spine surgery. A meta-analysis.
    The Journal of bone and joint surgery. American volume, 2008, Volume: 90, Issue:11

    Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Huma

2008
The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2009, Jan-20, Volume: 180, Issue:2

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Coronary Artery

2009
The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2009, Volume: 10, Issue:2

    Topics: Aminocaproates; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Child; Hemostatics; Humans; Plac

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Trans

2009
[Hemostatic management for cardiac surgical patients in the post-aprotinin era].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:3

    Topics: Aminocaproates; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass

2009
Aprotinin increases mortality as compared with tranexamic acid in cardiac surgery: a meta-analysis of randomized head-to-head trials.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Proced

2009
[Therapeutic options for perioperatively acquired platelet dysfunctions].
    Der Anaesthesist, 2009, Volume: 58, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Platelet Disorders; Deamino Arginine Vasopressi

2009
Pharmacological interventions to decrease blood loss and blood transfusion requirements for liver resection.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Antithrombin III; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Deamino Arginine Vasopressin;

2009
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Antifibrinolytics in major orthopaedic surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2010, Volume: 18, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Huma

2010
Interventions for preventing blood loss during the treatment of cervical intraepithelial neoplasia.
    The Cochrane database of systematic reviews, 2010, Jun-16, Issue:6

    Topics: Blood Loss, Surgical; Female; Ferric Compounds; Hemostasis, Surgical; Hemostatics; Humans; Randomize

2010
[A meta-analysis of the effectiveness and safety of using tranexamic acid in spine surgery].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2010, Jun-15, Volume: 48, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Loss, Surgical; Child; Child, Preschool; Female; H

2010
Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: a systematic review and meta-analysis.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass, Off-Pump;

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Antifibrinolytic drugs for acute traumatic injury.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemorrhage; Humans; Ran

2011
Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Trials as Topic; Female; Hemorrhage

2011
Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Trials as Topic; Female; Hemorrhage

2011
Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Trials as Topic; Female; Hemorrhage

2011
Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Trials as Topic; Female; Hemorrhage

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
    The Cochrane database of systematic reviews, 2011, Mar-16, Issue:3

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Erythrocyte Tran

2011
The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012, Volume: 20, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2012
The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012, Volume: 20, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2012
The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012, Volume: 20, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2012
The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012, Volume: 20, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2012
Methods to decrease blood loss and transfusion requirements for liver transplantation.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Factor VIIa; Hemostatic

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
    The Journal of bone and joint surgery. British volume, 2011, Volume: 93, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2011
Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Child

2012
Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Child

2012
Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Child

2012
Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Child

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
    BMJ (Clinical research ed.), 2012, May-17, Volume: 344

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Myocardial Infarction; Ran

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis.
    The Journal of bone and joint surgery. American volume, 2012, Jul-03, Volume: 94, Issue:13

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2012
A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use.
    Pediatric surgery international, 2012, Volume: 28, Issue:11

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Card

2012
Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies.
    BMJ (Clinical research ed.), 2012, Sep-11, Volume: 345

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2012
Systematic review and meta-analysis of the use of tranexamic acid in tonsillectomy.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorrhage; Tonsillectomy; Tran

2013
Minimising blood loss and transfusion in contemporary hip and knee arthroplasty.
    The Journal of bone and joint surgery. British volume, 2012, Volume: 94, Issue:11 Suppl A

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2012
The effect of tranexamic acid on blood loss in orthognathic surgery: a meta-analysis of randomized controlled trials.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 115, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Hematocrit; Hemoglobins;

2013
Tranexamic Acid reducing blood transfusion in children undergoing craniosynostosis surgery.
    The Journal of craniofacial surgery, 2013, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Craniosynostoses; Humans; In

2013
The management of perioperative bleeding.
    Blood reviews, 2003, Volume: 17, Issue:3

    Topics: Aprotinin; Blood Coagulation Disorders; Blood Loss, Surgical; Deamino Arginine Vasopressin; Factor V

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2003
Antifibrinolytics.
    Acta anaesthesiologica Belgica, 2003, Volume: 54, Issue:4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Hemo

2003
Strategies for minimizing blood loss in orthopedic surgery.
    Seminars in hematology, 2004, Volume: 41, Issue:1 Suppl 1

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Blood Loss, Surg

2004
Tranexamic acid for major spinal surgery.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2004, Volume: 13 Suppl 1

    Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Humans; Scolios

2004
Intraoperative blood management in joint replacement surgery.
    Orthopedics, 2004, Volume: 27, Issue:6 Suppl

    Topics: Antifibrinolytic Agents; Aprotinin; Arthroplasty, Replacement; Blood Loss, Surgical; Blood Transfusi

2004
[Reducing blood loss in total knee arthroplasty].
    Ugeskrift for laeger, 2004, Aug-02, Volume: 166, Issue:32

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drainage; Humans; Pe

2004
Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials.
    BMC cardiovascular disorders, 2005, Jul-04, Volume: 5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Bayes Theorem; Blood Loss, Surgical; Blood Tr

2005
Antifibrinolytics in liver transplantation.
    International anesthesiology clinics, 2006,Summer, Volume: 44, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Humans; Liver Transplan

2006
The use of antifibrinolytic agents in total hip arthroplasty: a meta-analysis.
    The Journal of arthroplasty, 2006, Volume: 21, Issue:6

    Topics: Antifibrinolytic Agents; Aprotinin; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Tran

2006
[Local and systemic hemostasis in surgery].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2007, Volume: 78, Issue:2

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Factor VIIa; Fibrin Tissue Adhesive; Hemos

2007
Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery.
    Circulation, 2007, Jun-05, Volume: 115, Issue:22

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Intra

2007
Current antifibrinolytic therapy for coronary artery revascularization.
    AANA journal, 2008, Volume: 76, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Coro

2008
Pro: tranexamic acid is better than aprotinin in decreasing bleeding after cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:4

    Topics: Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Hemostatics; H

1994
Con: tranexamic acid is not better than aprotinin in decreasing bleeding after cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:4

    Topics: Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Hemostatics; H

1994
Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.
    The Annals of thoracic surgery, 1994, Volume: 58, Issue:6

    Topics: Aminocaproic Acid; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Coronary Artery Byp

1994
Natural and synthetic antifibrinolytics in adult cardiac surgery: efficacy, effectiveness and efficiency.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:11

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusio

1994
Blood-sparing drugs: aprotinin, tranexamic acid, and epsilon-aminocaproic acid.
    International anesthesiology clinics, 1995,Winter, Volume: 33, Issue:1

    Topics: Aminocaproic Acid; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Graft Occlusion, Va

1995
Clinical use of synthetic antifibrinolytic agents during liver transplantation.
    Seminars in thrombosis and hemostasis, 1993, Volume: 19, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Loss, Surgical; Clini

1993
Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Aminocaproic Acid; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures;

1997
Hemostatic drugs.
    The New England journal of medicine, 1998, Jul-23, Volume: 339, Issue:4

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Blood Loss, Surgica

1998
Cardiac bypass haemostasis: putting blood through the mill.
    British journal of haematology, 1999, Volume: 104, Issue:2

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion, Autologous; Coronary Ar

1999
[Tranexamic acid reduces the blood loss in knee arthroplasty--if it's administered at the right time].
    Lakartidningen, 1999, Jun-16, Volume: 96, Issue:24

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Volume; Guidel

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
    Lancet (London, England), 1999, Dec-04, Volume: 354, Issue:9194

    Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac

1999
Interventions for preventing blood loss during the treatment of cervical intraepithelial neoplasia.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Blood Loss, Surgical; Female; Ferric Compounds; Hemostasis, Surgical; Hemostatics; Humans; Sulfates;

2000
Current status of non-transfusional haemostatic agents.
    Haematologica, 1999, Volume: 84 Suppl EHA-4

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Blood Loss, Surg

1999
Retrospective review of the management of elective surgery with desmopressin and clotting factor concentrates in patients with von Willebrand disease.
    American journal of hematology, 2001, Volume: 66, Issue:4

    Topics: Anesthesia, Obstetrical; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Deamino Ar

2001
[Tranexamic acid reduces blood loss and the need of blood transfusion after knee arthroplasty].
    Ugeskrift for laeger, 2002, Jan-14, Volume: 164, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2002

Trials

478 trials available for tranexamic acid and Blood Loss, Surgical

ArticleYear
The effect of tranexamic acid on blood loss in orthognathic surgery: a randomized, placebo-controlled, equivalence study.
    International journal of oral and maxillofacial surgery, 2022, Volume: 51, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Orthognathic Surgery; Or

2022
Multimodal Peri-articular Injection with Tranexamic Acid can reduce postoperative blood loss versus Intravenous Tranexamic Acid in Total Knee Arthroplasty: A Randomized Controlled Trial.
    Journal of orthopaedic surgery and research, 2021, Sep-03, Volume: 16, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2021
Comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Adult; Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Humans; Prospecti

2022
Re-Evaluating the Effect of Preoperative Tranexamic Acid on Blood Loss and Field Quality During Rhinoplasty: A Randomized Double-Blinded Controlled Trial.
    Aesthetic plastic surgery, 2022, Volume: 46, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Rhinoplasty; Tranexamic

2022
Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total knee arthroplasty: results of a randomized controlled trial (TRAC-24).
    The bone & joint journal, 2021, Volume: 103-B, Issue:10

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antif

2021
Effects of carbazochrome sodium sulfonate combined with tranexamic acid on hemostasis and inflammation during perioperative period of total hip arthroplasty: A randomized controlled trial.
    Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:1

    Topics: Adrenochrome; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemosta

2022
Use of a Multifunctional Cocktail for Postoperative Bleeding and Pain Control in Spinal Fusion: A Randomized, Double-blind, Controlled Trial.
    Spine, 2022, 09-15, Volume: 47, Issue:18

    Topics: Analgesics, Opioid; Blood Loss, Surgical; Double-Blind Method; Hemoglobins; Humans; Pain; Pain Manag

2022
Characterisation of Plasma Mitochondrial DNA, MMP-9 and Neutrophil Elastase in Patients Undergoing Coronary Artery Bypass Grafting: Effects of Tranexamic Acid and Postoperative Pneumonia.
    Heart, lung & circulation, 2022, Volume: 31, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; DNA, Mitochondrial; Humans; L

2022
The efficacy, safety, and cost-effectives of combined administration of Intravenous and Local Tranexamic Acid in the management of Patients Undergoing Primary Total Hip Arthroplasty: A prospective, blinded and randomized clinical study.
    Acta orthopaedica et traumatologica turcica, 2021, Volume: 55, Issue:5

    Topics: Administration, Intravenous; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; B

2021
Synergistic Effect of a Prolonged Combination Course of Tranexamic Acid and Dexamethasone Involving High Initial Doses in Total Knee Arthroplasty: A Randomized Controlled Trial.
    The journal of knee surgery, 2023, Volume: 36, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial.
    Spine, 2022, Feb-01, Volume: 47, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorr

2022
Topical administration of tranexamic acid in elderly patients undergoing short femoral nailing for intertrochanteric fracture: A randomised controlled trial.
    Injury, 2022, Volume: 53, Issue:2

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Int

2022
Study protocol: haemostatic efficacy and safety of preemptive antifibrinolysis with multidose intravenous tranexamic acid in elderly hip fracture patients: design of a prospective randomised controlled trial.
    BMJ open, 2021, 12-14, Volume: 11, Issue:12

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostatics; Hip F

2021
Tranexamic acid administration for arthroscopic rotator cuff repair: A prospective, double-blind, randomized controlled trial.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2023, Volume: 28, Issue:2

    Topics: Arthroscopy; Blood Loss, Surgical; Humans; Prospective Studies; Rotator Cuff; Rotator Cuff Injuries;

2023
Effect of single dose intravenous tranexamic acid on blood loss in tangential excision of burn wounds - A double blind randomised controlled trial.
    Burns : journal of the International Society for Burn Injuries, 2022, Volume: 48, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Burns; Double-Blind Method; Hemoglobins; Humans; Pros

2022
Pre-Emptive Antifibrinolysis: Its Role and Efficacy in Hip Fracture Patients Undergoing Total Hip Arthroplasty.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hip Fractures;

2022
Invited Discussion on: Re-evaluating the Effect of Preoperative Tranexamic Acid on Blood Loss and Field Quality During Rhinoplasty: A Randomized double-blinded controlled Trial.
    Aesthetic plastic surgery, 2022, Volume: 46, Issue:3

    Topics: Blood Loss, Surgical; Double-Blind Method; Humans; Postoperative Hemorrhage; Rhinoplasty; Tranexamic

2022
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery.
    Trials, 2022, Jan-31, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Hypotension; Perioperative Care; Tranexamic A

2022
Safety of intravenous tranexamic acid in patients undergoing supratentorial meningiomas resection: protocol for a randomised, parallel-group, placebo control, non-inferiority trial.
    BMJ open, 2022, Feb-02, Volume: 12, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Meningeal Neoplasms; Men

2022
Safety and efficacy of aprotinin versus tranexamic acid for reducing absolute blood loss and transfusion in pediatric patients undergoing craniosynostosis surgery: a randomized, double-blind, three-arm controlled trial.
    Journal of neurosurgery. Pediatrics, 2022, 05-01, Volume: 29, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Child; Craniosyn

2022
Tranexamic acid combined with compression dressing reduces blood loss in gluteal muscle contracture surgery.
    BMC surgery, 2022, Feb-11, Volume: 22, Issue:1

    Topics: Antifibrinolytic Agents; Bandages; Blood Loss, Surgical; Contracture; Humans; Muscles; Postoperative

2022
Should tranexamic acid be used for 3 days after total knee replacement? A randomized study in 250 patients.
    Acta orthopaedica Belgica, 2021, Volume: 87, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Hemoglobins; Humans;

2021
Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing liver resection: protocol for the haemorrhage during liver resection tranexamic acid (HeLiX) randomised controlled trial.
    BMJ open, 2022, Feb-24, Volume: 12, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Liver; Prospective Studies

2022
Safety and efficacy of preoperative tranexamic acid in reducing intraoperative and postoperative blood loss in high-risk women undergoing cesarean delivery: a randomized controlled trial.
    BMC pregnancy and childbirth, 2022, Mar-14, Volume: 22, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Electiv

2022
The Effect of Topical Tranexamic Acid in Endoscopic Sinus Surgery: A Triple Blind Randomized Clinical Trial.
    The Annals of otology, rhinology, and laryngology, 2023, Volume: 132, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Endoscopy; Humans; Sinusitis; Tr

2023
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Apr-15, Volume: 36, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2022
Is intravenous tranexamic acid effective in reduction of blood loss during pelvic and acetabular surgery?
    International orthopaedics, 2022, Volume: 46, Issue:8

    Topics: Acetabulum; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Prospective Studies; Tranexamic A

2022
Comparison of the therapeutic efficacy of topical tranexamic acid, epinephrine, and lidocaine in stopping bleeding in non-traumatic epistaxis: a prospective, randomized, double-blind study.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:9

    Topics: Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Me

2022
Omission of tranexamic acid does not increase the amount of perioperative blood transfusions in patients undergoing one-level spinal fusion surgery: a retrospective propensity score-matched noninferiority study.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Propensity Score; Retrospe

2023
Randomized, controlled trial of two tranexamic acid dosing protocols in adult spinal deformity surgery.
    Spine deformity, 2022, Volume: 10, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Prospective Studies; Seizures; Tranexa

2022
Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial.
    Plastic and reconstructive surgery, 2022, 09-01, Volume: 150, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Hemoglobins; Humans; Lys

2022
A randomized, placebo-controlled, double-blinded pilot study of angiotensin 1-7 (TXA-127) for the treatment of severe COVID-19.
    Critical care (London, England), 2022, 07-28, Volume: 26, Issue:1

    Topics: Angiotensin I; Antifibrinolytic Agents; Blood Loss, Surgical; COVID-19; Double-Blind Method; Humans;

2022
Value of Tranexamic Acid and Progressive Nursing in Accelerating Postoperative Rehabilitation After Total Knee Arthroplasty.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:1

    Topics: Activities of Daily Living; Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Kne

2023
The addition of oral Tranexamic acid to knee arthroplasty patients does not further improve blood loss: a double blinded randomized control trial.
    Acta orthopaedica Belgica, 2022, Volume: 88, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2022
Safety and efficacy of perioperative tranexamic acid infusion in acetabular fracture fixation: A randomized placebo-controlled double-blind prospective study.
    Injury, 2022, Volume: 53, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Internal; Hemoglobins; Hip Fractur

2022
Comparison of Intravenous and Topical Tranexamic Acid in Total Joint Arthroplasty.
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2022, Volume: 89, Issue:4

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2022
A randomized control trial on the role of tranexamic acid in preventing intraoperative bleeding during external dacryocystorhinostomy.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:10

    Topics: Blood Loss, Surgical; Dacryocystorhinostomy; Double-Blind Method; Female; Humans; Lacrimal Duct Obst

2022
Tranexamic acid effects in postoperative bleeding outcomes in laparoscopic sleeve gastrectomy: a controlled study.
    Acta cirurgica brasileira, 2022, Volume: 37, Issue:7

    Topics: Adolescent; Adult; Aged; Anticoagulants; Antifibrinolytic Agents; Blood Loss, Surgical; Gastrectomy;

2022
A single dose of tranexamic acid infusion is safe and effective to reduce total blood loss during proximal femoral nailing for intertrochanteric fractures: A prospective randomized study.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Fracture Fixation, Intramedullary; Hip Fracture

2022
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial.
    The British journal of surgery, 2023, 01-10, Volume: 110, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Pancreaticoduoden

2023
Effectiveness of oral versus intravenous tranexamic acid in primary total hip and knee arthroplasty: a randomised, non-inferiority trial.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
Effectiveness of oral versus intravenous tranexamic acid in primary total hip and knee arthroplasty: a randomised, non-inferiority trial.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
Effectiveness of oral versus intravenous tranexamic acid in primary total hip and knee arthroplasty: a randomised, non-inferiority trial.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
Effectiveness of oral versus intravenous tranexamic acid in primary total hip and knee arthroplasty: a randomised, non-inferiority trial.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2023
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022, Dec-15, Volume: 36, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthrodesis; Blood Loss, Surgical; Bone Screws; Fracture Fixation, In

2022
Effectiveness of different antithrombotic agents in combination with tranexamic acid for venous thromboembolism prophylaxis and blood management after total knee replacement: a prospective randomized study.
    BMC musculoskeletal disorders, 2023, Jan-04, Volume: 24, Issue:1

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Dalt

2023
Tranexamic acid does not significantly lower postoperative bleeding after endoscopic sinus and nasal surgery.
    International forum of allergy & rhinology, 2023, Volume: 13, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Epistaxis; Humans; Nasal Surgica

2023
Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind Randomized Controlled Trial.
    Plastic and reconstructive surgery, 2023, 10-01, Volume: 152, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Breast Ne

2023
Efficacy of intravenous tranexamic acid administration in medial opening-wedge distal tibial tuberosity osteotomy (MOWDTO) for varus knee osteoarthritis: a randomized control trial.
    Journal of orthopaedic surgery and research, 2023, Mar-08, Volume: 18, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Osteoarthritis,

2023
The effect of intravenous unit-dose tranexamic acid on visible and hidden blood loss in posterior lumbar interbody fusion: a randomized clinical trial.
    Scientific reports, 2023, 03-22, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; C-Reactive Protein; Hemostatics; Humans; Postoperativ

2023
Intraoperative use of tranexamic acid to reduce blood loss during cytoreductive surgery for advanced ovarian cancer: A randomized controlled clinical trial.
    Acta obstetricia et gynecologica Scandinavica, 2023, Volume: 102, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Carcinoma, Ovarian Epithelial; Cytoreduction Surgical

2023
Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery.
    The New England journal of medicine, 2023, Apr-13, Volume: 388, Issue:15

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cesarean Section; Chemoprevention;

2023
Single Dose of Tranexamic Acid Effectively Reduces Blood Loss in Patients Undergoing Spine Surgery: A Prospective Randomized Controlled Trial.
    World neurosurgery, 2023, Volume: 175

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Prospective Studies; Spine; Tranexamic Acid

2023
Tourniquets can further reduce perioperative blood loss in patients on dexamethasone and tranexamic acid during cemented total knee arthritis: a single-center, double-blind, randomized controlled trial.
    Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2023, Apr-29, Volume: 24, Issue:1

    Topics: Albumins; Antifibrinolytic Agents; Arthritis; Blood Loss, Surgical; Dexamethasone; Humans; Inflammat

2023
Medullary cavity application of tranexamic acid to reduce blood loss in tibial intramedullary nailing procedures-a randomized controlled trial.
    International orthopaedics, 2023, Volume: 47, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Exsanguination; Fracture Fixation, Intramedullary; Hu

2023
Topical use of tranexamic acid can reduce opioid consumption compared with intravenous use for patients undergoing primary total hip arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2023, Jun-03, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Analgesics, Opioid; Antifibrinolytic Agents; A

2023
Comparative study between oxytocin and combination of tranexamic acid and ethamsylate in reducing intra-operative bleeding during emergency and elective cesarean section after 38 weeks of normal pregnancy.
    BMC pregnancy and childbirth, 2023, Jun-12, Volume: 23, Issue:1

    Topics: Blood Loss, Surgical; Cesarean Section; Ethamsylate; Female; Humans; Oxytocin; Pregnancy; Pregnancy

2023
Comparative study of carbazochrome sodium sulfonate and tranexamic acid in reducing blood loss and inflammatory response following direct anterior total hip arthroplasty: a prospective randomized controlled trial.
    International orthopaedics, 2023, Volume: 47, Issue:10

    Topics: Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgi

2023
Tranexamic acid administration for the prevention of periprosthetic joint infection and surgical site infection: a systematic review and meta-analysis.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement,

2023
[Effects of Tranexamic Acid on Perioperative Blood Loss and Wound Hematoma Development in Lumbar Spine Surgery: a Prospective Randomized Study].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2023, Volume: 90, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hematoma; Humans; Postoperative Hemorrhage; Prospecti

2023
Peroperative administration of tranexamic acid in sleeve gastrectomy to reduce hemorrhage: a double-blind randomized controlled trial.
    Surgical endoscopy, 2023, Volume: 37, Issue:10

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Hum

2023
Risk of bleeding in anticoagulated patients undergoing dental extraction treated with topical tranexamic acid compared to collagen-gelatin sponge: Randomized clinical trial.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2023, Volume: 51, Issue:6

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Collagen; Gelatin; Humans; P

2023
A randomised controlled trial of tranexamic acid versus misoprostol in reducing blood loss during caesarean section.
    Ghana medical journal, 2022, Volume: 56, Issue:2

    Topics: Blood Loss, Surgical; Cesarean Section; Female; Humans; Misoprostol; Oxytocics; Oxytocin; Pregnancy;

2022
Topical combined tranexamic acid and epinephrine versus topical epinephrine in control of intraoperative bleeding of external dacryocystorhinostomy.
    International ophthalmology, 2023, Volume: 43, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Dacryocystorhinostomy; Epine

2023
Efficacy of perioperative cryotherapy combined with intra-articular injection of tranexamic acid in total knee arthroplasty.
    Medicine, 2023, Jul-21, Volume: 102, Issue:29

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Injections,

2023
Oxytocin versus a combination of tranexamic acid and ethamsylate in reducing intraoperative bleeding during abdominal myomectomy: a randomized clinical trial.
    BMC women's health, 2023, 07-29, Volume: 23, Issue:1

    Topics: Blood Loss, Surgical; Ethamsylate; Female; Humans; Leiomyoma; Oxytocin; Saline Solution; Tranexamic

2023
The effect of tranexamic acid on perioperative blood loss in transurethral resection of the prostate: A double-blind, randomized controlled trial.
    The Prostate, 2023, Volume: 83, Issue:16

    Topics: Blood Loss, Surgical; Hemoglobins; Humans; Male; Prospective Studies; Prostate; Tranexamic Acid; Tra

2023
Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial.
    BMC pregnancy and childbirth, 2023, Aug-25, Volume: 23, Issue:1

    Topics: Blood Loss, Surgical; Cesarean Section; Female; Humans; Misoprostol; Oxytocin; Postoperative Hemorrh

2023
The effect of tranexamic acid on intraoperative blood loss in patients undergoing brain meningioma resections: Study protocol for a randomized controlled trial.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Blood Loss, Surgical; Brain; Humans; Meningeal Neoplasms; Meningioma; Randomized Controlled Trials a

2023
Tranexamic acid is safe with respect to the risk of deep venous thrombosis in patients with hemophilic arthritis undergoing total knee arthroplasty without chemoprophylaxis: A prospective study.
    The Knee, 2023, Volume: 44

    Topics: Administration, Intravenous; Adult; Anticoagulants; Antifibrinolytic Agents; Arthritis; Arthroplasty

2023
[Efficacy and safety of multiple-dose intravenous tranexamic acid for reducing blood loss in complex tibial plateau fractures: A prospective randomized controlled trial].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2023, Sep-15, Volume: 37, Issue:9

    Topics: Blood Loss, Surgical; Humans; Interleukin-6; Prospective Studies; Thrombosis; Tibial Fractures; Tibi

2023
Clinical utilization of methylprednisolone in conjunction with tranexamic acid for accelerated rehabilitation in total hip arthroplasty.
    Journal of orthopaedic surgery and research, 2023, Oct-04, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Methylprednis

2023
Intravenous tranexamic acid for intracerebral meningioma resections: A randomized, parallel-group, non-inferiority trial.
    Journal of clinical anesthesia, 2024, Volume: 92

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Meningeal Neoplasms; Men

2024
Effect of Tranexamic Acid on Postoperative Bleeding in Sleeve Gastrectomy: a Randomized Trial.
    Obesity surgery, 2023, Volume: 33, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Obesity, Morbid; Postoperative Hemorrhage; Tr

2023
Blood-conserving and therapeutic efficacy of intravenous tranexamic acid at different time points after primary total knee arthroplasty with tourniquet application: a randomised controlled trial.
    BMC musculoskeletal disorders, 2023, Nov-17, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The efficacy of temperature intervention combined with tranexamic acid in reducing blood loss and accelerating recovery during spinal fusion.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Postoperative Hemorrhage; Pulmon

2023
Effect of intravenous low-dose norepinephrine on blood loss in non-tourniquet total knee arthroplasty under general anesthesia: a randomized, double-blind, controlled, single-center trial.
    Journal of orthopaedic surgery and research, 2023, Dec-07, Volume: 18, Issue:1

    Topics: Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical;

2023
[Efficacy and safety of a loading high-dose tranexamic acid followed by postoperative five doses in total hip arthroplasty: A randomized controlled trial].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019, Aug-15, Volume: 33, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2019
Efficacy and Safety of Tranexamic Acid in Intertrochanteric Fractures: A Single-Blind Randomized Controlled Trial.
    Orthopaedic surgery, 2019, Volume: 11, Issue:4

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;

2019
Perioperative combined administration of tranexamic acid and dexamethasone in total knee arthroplasty-benefit versus harm?
    Medicine, 2019, Volume: 98, Issue:34

    Topics: Aged; Analgesics; Anti-Inflammatory Agents; Antiemetics; Antifibrinolytic Agents; Arthroplasty, Repl

2019
Hemostatic and Anti-Inflammatory Effects of Carbazochrome Sodium Sulfonate in Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Trial.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Adrenochrome; Anti-Inflammatory Agents; Antifi

2020
Comparison of oral vs. combined topical/intravenous/oral tranexamic acid in the prevention of blood loss in total knee arthroplasty: A randomised clinical trial.
    Orthopaedics & traumatology, surgery & research : OTSR, 2019, Volume: 105, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2019
Tranexamic acid or epsilon-aminocaproic acid in total joint arthroplasty? A randomized controlled trial.
    The bone & joint journal, 2019, Volume: 101-B, Issue:9

    Topics: Administration, Intravenous; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replace

2019
[Effect of tranexamic acid combined flexion position of hip and knee on perioperative bleeding following unilateral total knee arthroplasty].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2019, Aug-25, Volume: 32, Issue:8

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2019
Monitoring of fibrinolytic system activity with plasminogen, D-dimers and FDP in primary total knee arthroplasty (TKA) after topical, intravenous or combined administration of tranexamic acid.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020, Volume: 164, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2020
Effect of topical tranexamic acid in total hip arthroplasty patients who receive continuous aspirin for prevention of cardiovascular or cerebrovascular events: A prospective randomized study.
    Orthopaedics & traumatology, surgery & research : OTSR, 2019, Volume: 105, Issue:7

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2019
Adjunctive use of tranexamic acid to tourniquet in reducing haemorrhage during abdominal myomectomy - A randomized controlled trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2019, Volume: 242

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Humans; Leiomyoma

2019
Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial.
    British journal of anaesthesia, 2020, Volume: 124, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aortic Aneurysm; Blood Loss, Surgical; Blood Transfusion; Cardiac Sur

2020
Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial.
    British journal of anaesthesia, 2020, Volume: 124, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aortic Aneurysm; Blood Loss, Surgical; Blood Transfusion; Cardiac Sur

2020
Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial.
    British journal of anaesthesia, 2020, Volume: 124, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aortic Aneurysm; Blood Loss, Surgical; Blood Transfusion; Cardiac Sur

2020
Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial.
    British journal of anaesthesia, 2020, Volume: 124, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aortic Aneurysm; Blood Loss, Surgical; Blood Transfusion; Cardiac Sur

2020
Intravenous and subsequent long-term oral tranexamic acid in enhanced-recovery primary total knee arthroplasty without the application of a tourniquet: a randomized placebo-controlled trial.
    BMC musculoskeletal disorders, 2019, Oct-25, Volume: 20, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2019
Combined use of intravenous and topical tranexamic acid in patients aged over 70 years old undergoing total hip arthroplasty.
    Journal of orthopaedic surgery and research, 2019, Nov-07, Volume: 14, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agen

2019
Does tranexamic acid improve intra-operative visualisation in endoscopic ear surgery? A double-blind, randomised, controlled trial.
    The Journal of laryngology and otology, 2019, Volume: 133, Issue:12

    Topics: Adolescent; Adult; Anatomic Landmarks; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind M

2019
Tranexamic acid has no advantage in head and neck surgical procedures: a randomised, double-blind, controlled clinical trial.
    The Journal of laryngology and otology, 2019, Volume: 133, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Humans; Male; Mid

2019
Intravenous Tranexamic Acid for Brain Contusion with Intraparenchymal Hemorrhage: Randomized, Double-Blind, Placebo-Controlled Trial.
    Reviews on recent clinical trials, 2020, Volume: 15, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Brain Contusion; Brain Hemorrhage, Traum

2020
Safety and efficacy of tranexamic acid in paediatric cardiac surgery: study protocol for a double-blind randomised controlled trial.
    BMJ open, 2019, 11-25, Volume: 9, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Cardi

2019
Comparison of Floseal® and Tranexamic Acid for Bleeding Control after Total Knee Arthroplasty: a Prospective Randomized Study.
    Clinics (Sao Paulo, Brazil), 2019, Volume: 74

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies; Female; Follow-Up Studi

2019
Tranexamic acid use in high-risk blood transfusion patients undergoing total hip replacement: a randomised controlled trial.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2021, Volume: 31, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2021
Application of thromboelastography to evaluate the effect of different routes administration of tranexamic acid on coagulation function in total hip arthroplasty.
    Journal of orthopaedic surgery and research, 2019, Dec-11, Volume: 14, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2019
Tranexamic acid in ENT.
    The Journal of laryngology and otology, 2019, Volume: 133, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Brain Injuries, Traumatic; Humans; Otolaryngology; Pl

2019
The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial.
    International orthopaedics, 2020, Volume: 44, Issue:3

    Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty,

2020
A new improvement: subperiosteal cocktail application to effectively reduce pain and blood loss after total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2020, Jan-30, Volume: 15, Issue:1

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; Blood Loss, Sur

2020
Comparison of hemocoagulase atrox versus tranexamic acid used in primary total knee arthroplasty: A randomized controlled trial.
    Thrombosis research, 2020, Volume: 188

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Batroxobin; B

2020
Intraoperative Intravenous and Intra-Articular Plus Postoperative Intravenous Tranexamic Acid in Total Knee Arthroplasty: A Placebo-Controlled Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2020, Apr-15, Volume: 102, Issue:8

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2020
Outcome impact of different tranexamic acid regimens in cardiac surgery with cardiopulmonary bypass (OPTIMAL): Rationale, design, and study protocol of a multicenter randomized controlled trial.
    American heart journal, 2020, Volume: 222

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical;

2020
Hidden blood loss in direct anterior total hip arthroplasty: a prospective, double blind, randomized controlled trial on topical versus intravenous tranexamic acid.
    Musculoskeletal surgery, 2021, Volume: 105, Issue:3

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2021
Topical co-delivery of platelet rich fibrin and tranexamic acid does not decrease blood loss in primary total knee arthroplasty compared to the standard of care: a prospective, randomized, controlled trial.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021, Volume: 29, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2021
Effects of Intravenous Tranexamic Acid During Rhytidectomy: A Randomized, Controlled, Double-Blind Pilot Study.
    Aesthetic surgery journal, 2021, 01-25, Volume: 41, Issue:2

    Topics: Blood Loss, Surgical; Double-Blind Method; Humans; Pilot Projects; Postoperative Hemorrhage; Prospec

2021
Tranexamic acid reduce hidden blood loss in posterior lumbar interbody fusion (PLIF) surgery.
    Medicine, 2020, Volume: 99, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Lumbar Vertebrae; Male; Middle Aged;

2020
Topical tranexamic acid in cemented primary total knee arthroplasty without tourniquet: a prospective randomized study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020, Volume: 30, Issue:6

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2020
Orthognathic Surgery-Induced Fibrinolytic Shutdown Is Amplified by Tranexamic Acid.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2020, Volume: 78, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Double-Blind Method;

2020
Intraoperative tranexamic acid to decrease blood loss during myomectomy: a randomized, double-blind, placebo-controlled trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Humans; Injection

2020
Additional benefits of multiple-dose tranexamic acid to anti-fibrinolysis and anti-inflammation in total knee arthroplasty: a randomized controlled trial.
    Archives of orthopaedic and trauma surgery, 2020, Volume: 140, Issue:8

    Topics: Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surg

2020
Tranexamic acid for the Latarjet procedure: a randomized controlled trial.
    Journal of shoulder and elbow surgery, 2020, Volume: 29, Issue:5

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antifibrinolytic Agents; Blood Loss, Surgica

2020
Two Doses of Tranexamic Acid Reduce Blood Loss in Primary Posterior Lumbar Fusion Surgery: A Randomized-controlled Trial.
    Clinical spine surgery, 2020, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Lumbosacral Region; Tranex

2020
Results after the application of tranexamic acid intravenous or intra-articular in the control of postsurgical bleeding after total hip arthroplasty: a randomized controlled trial.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020, Volume: 30, Issue:7

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2020
Tranexamic acid in total knee replacement which protocol? which application form? A prospective randomised study.
    Acta orthopaedica Belgica, 2019, Volume: 85, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2019
Effectiveness of different doses and routes of administration of tranexamic acid for total hip replacement.
    International orthopaedics, 2021, Volume: 45, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2021
Tranexamic acid safely reduces hidden blood loss in patients undergoing intertrochanteric fracture surgery: a randomized controlled trial.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Meta-Analysis as Topic; Tranex

2022
Effect of topical tranexamic acid on post-traumatic elbow stiffness in patients treated with open arthrolysis: a prospective comparative study.
    Journal of shoulder and elbow surgery, 2020, Volume: 29, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Drainage; Elbow; Elbow Joint; Female; Humans;

2020
Effect of tranexamic acid on blood loss after reverse total shoulder arthroplasty according to the administration method: a prospective, multicenter, randomized, controlled study.
    Journal of shoulder and elbow surgery, 2020, Volume: 29, Issue:6

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthritis; Arth

2020
Topical Tranexamic Acid in Total Knee Arthroplasty: Does It Augment the Effect of the Intravenous Administration in Patients with Moderate-to-High Risk of Bleeding? A Randomized Clinical Trial.
    The journal of knee surgery, 2021, Volume: 34, Issue:14

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2021
Tranexamic Acid Is Associated With Improved Operative Field in Orthognathic Surgery.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2020, Volume: 78, Issue:9

    Topics: Adolescent; Adult; Blood Loss, Surgical; Child; Dexmedetomidine; Double-Blind Method; Female; Humans

2020
Intravenous versus topical tranexamic acid in lumbar interbody fusion: A protocol of randomized controlled trial.
    Medicine, 2020, Jun-12, Volume: 99, Issue:24

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical;

2020
High-dose versus low-dose tranexamic acid for paediatric craniosynostosis surgery: a double-blind randomised controlled non-inferiority trial.
    British journal of anaesthesia, 2020, Volume: 125, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child, Preschool; Craniosynostoses; Dose-Response Rel

2020
Effectiveness of preemptive antifibrinolysis with tranexamic acid in rheumatoid arthritis patients undergoing total knee arthroplasty: a study protocol for a randomized controlled trial.
    BMC musculoskeletal disorders, 2020, Jul-15, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Replaceme

2020
Combined use of tranexamic acid and rivaroxaban in posterior lumbar interbody fusion safely reduces blood loss and transfusion rates without increasing the risk of thrombosis-a prospective, stratified, randomized, controlled trial.
    International orthopaedics, 2020, Volume: 44, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Prospective Studies; Rivar

2020
Randomized prospective evaluation of the use of tranexamic acid and effects on blood loss for proximal humeral fracture surgery.
    Journal of shoulder and elbow surgery, 2020, Volume: 29, Issue:8

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2020
Tranexamic acid is beneficial for blood management of high tibial osteotomy: a randomized controlled study.
    Archives of orthopaedic and trauma surgery, 2021, Volume: 141, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Middle Aged; Osteotomy; Postoperative Hemorrh

2021
Preoperative tranexamic acid does not reduce transfusion rates in major oncologic surgery: Results of a randomized, double-blind, and placebo-controlled trial.
    Journal of surgical oncology, 2020, Volume: 122, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female; Follo

2020
Combined use of intravenous and topical tranexamic acid efficiently reduces blood loss in patients aged over 60 operated with a 2-level lumbar fusion.
    Journal of orthopaedic surgery and research, 2020, Aug-20, Volume: 15, Issue:1

    Topics: Administration, Topical; Age Factors; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2020
Multiple-dose tranexamic acid for perioperative blood loss in total knee arthroplasty in patients with rheumatoid arthritis:a single-blinded, randomised, parallel-controlled study protocol in China.
    BMJ open, 2020, 08-20, Volume: 10, Issue:8

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Rep

2020
Better Treatment Values in Local Application of Tranexamic Acid (TXA) than Intravenous Application with the Same Dose in Total Hip Arthroplasty.
    Advances in therapy, 2020, Volume: 37, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Postoperative

2020
The efficacy and safety of intravenous tranexamic acid in anterior cruciate ligament reconstruction: A randomized controlled trial protocol.
    Medicine, 2020, Aug-21, Volume: 99, Issue:34

    Topics: Anterior Cruciate Ligament Reconstruction; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tran

2020
Intravenous tranexamic acid reduces blood loss and transfusion requirements after periacetabular osteotomy.
    The bone & joint journal, 2020, Volume: 102-B, Issue:9

    Topics: Acetabulum; Administration, Intravenous; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Sur

2020
Optimal dose of topical tranexamic acid considering efficacy and safety in total knee arthroplasty: a randomized controlled study.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021, Volume: 29, Issue:10

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2021
Effect of tranexamic acid on markers of inflammation in children undergoing craniofacial surgery.
    Acta anaesthesiologica Scandinavica, 2021, Volume: 65, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Child; Double-Blind Method; Humans; Infla

2021
Tranexamic acid reduces blood cost in long-segment spinal fusion surgery: A randomized controlled study protocol.
    Medicine, 2020, 09-11, Volume: 99, Issue:37

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female; Human

2020
Prophylactic use of tranexamic acid for prevention of bleeding during transbronchial lung biopsies - A randomized, double-blind, placebo-controlled trial.
    Respiratory medicine, 2020, Volume: 173

    Topics: Aged; Antifibrinolytic Agents; Biopsy; Blood Loss, Surgical; Bronchi; Double-Blind Method; Female; H

2020
Is Preoperative Administration of Tranexamic Acid Effective on Blood Loss Reduction in Mandibular Fracture Surgeries? A Triple-Blind Randomized Clinical Trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2021, Volume: 79, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Chicago; Female;

2021
The effect of multiple-dose oral versus intravenous tranexamic acid in reducing postoperative blood loss and transfusion rate after adolescent scoliosis surgery: a randomized controlled trial.
    The spine journal : official journal of the North American Spine Society, 2021, Volume: 21, Issue:2

    Topics: Administration, Intravenous; Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Post

2021
Combined and intravenous administration of TXA reduces blood loss more than topical administration in primary total knee arthroplasty: A randomized clinical trial.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2022, Volume: 166, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2022
Topical use of tranexamic acid versus epinephrine to optimise surgical field during exploratory tympanotomy.
    Anaesthesia, critical care & pain medicine, 2020, Volume: 39, Issue:6

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Epinephrine; Humans; Tranexa

2020
Pre-operative tranexemic acid vs. etamsylate in reducing blood loss during elective cesarean section: randomized controlled trial.
    Journal of perinatal medicine, 2021, Mar-26, Volume: 49, Issue:3

    Topics: Adult; Blood Loss, Surgical; Blood Transfusion; Cesarean Section; Double-Blind Method; Elective Surg

2021
Tranexamic ACid during PancereaticoDuodenectomy (TAC-PD): study protocol for a multicentre randomised, blind, placebo-controlled trial.
    BMJ open, 2020, 11-03, Volume: 10, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Japan; Multicenter Studi

2020
The Optimal Dosing Regimen for Tranexamic Acid in Revision Total Hip Arthroplasty: A Multicenter Randomized Clinical Trial.
    The Journal of bone and joint surgery. American volume, 2020, Nov-04, Volume: 102, Issue:21

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2020
Prophylactic use of tranexamic acid for decreasing the blood loss in elective cesarean section: A placebo-controlled randomized clinical trial.
    Journal of gynecology obstetrics and human reproduction, 2021, Volume: 50, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cesarean Section; Double-Bl

2021
The influence of topical use of tranexamic acid in reducing blood loss on early operation for thoracolumbar burst fracture: a randomized double-blinded controlled study.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021, Volume: 30, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorr

2021
Effect of Multiple Doses of Intravenous Tranexamic Acid on Perioperative Blood Loss in Total Knee Arthroplasty: A Randomized Controlled Study.
    Orthopaedic surgery, 2021, Volume: 13, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2021
Is serum gentamicin concentration modified with autologous cell-saved blood transfusion after total knee arthroplasty using tranexamic acid? A randomised control trial.
    Orthopaedics & traumatology, surgery & research : OTSR, 2021, Volume: 107, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; B

2021
Effects of Different Applications of Tranexamic Acid on Perioperative Blood Transfusion Rate and Postoperative Pain in Unilateral Total Knee Arthroplasty.
    Advances in therapy, 2021, Volume: 38, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
Safety and Efficacy of Using Tranexamic Acid at the Beginning of Robotic-Assisted Radical Prostatectomy in a Double-Blind Prospective Randomized Pilot Study.
    Acta medica (Hradec Kralove), 2020, Volume: 63, Issue:4

    Topics: Adult; Aged; Blood Loss, Surgical; Double-Blind Method; Fibrinolytic Agents; Humans; Male; Middle Ag

2020
Safety and Efficacy of Using Tranexamic Acid at the Beginning of Robotic-Assisted Radical Prostatectomy in a Double-Blind Prospective Randomized Pilot Study.
    Acta medica (Hradec Kralove), 2020, Volume: 63, Issue:4

    Topics: Adult; Aged; Blood Loss, Surgical; Double-Blind Method; Fibrinolytic Agents; Humans; Male; Middle Ag

2020
Safety and Efficacy of Using Tranexamic Acid at the Beginning of Robotic-Assisted Radical Prostatectomy in a Double-Blind Prospective Randomized Pilot Study.
    Acta medica (Hradec Kralove), 2020, Volume: 63, Issue:4

    Topics: Adult; Aged; Blood Loss, Surgical; Double-Blind Method; Fibrinolytic Agents; Humans; Male; Middle Ag

2020
Safety and Efficacy of Using Tranexamic Acid at the Beginning of Robotic-Assisted Radical Prostatectomy in a Double-Blind Prospective Randomized Pilot Study.
    Acta medica (Hradec Kralove), 2020, Volume: 63, Issue:4

    Topics: Adult; Aged; Blood Loss, Surgical; Double-Blind Method; Fibrinolytic Agents; Humans; Male; Middle Ag

2020
Optimal Route for Tranexamic Acid in Diabetics and Obese Patients Undergoing Primary Total Knee Arthroplasty - a Data from Randomized Study.
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2020, Volume: 87, Issue:6

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2020
A single dose of tranexamic acid reduces blood loss after reverse and anatomic shoulder arthroplasty: a randomized controlled trial.
    Journal of shoulder and elbow surgery, 2021, Volume: 30, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Transfusio

2021
The effect of intravenous tranexamic acid on visual clarity during arthroscopic rotator cuff repair: A randomized, double-blinded, placebo-controlled pilot study.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty; Arthroscopy; Blood Loss, Surgica

2020
The effect of intravenous tranexamic acid on visual clarity during arthroscopic rotator cuff repair: A randomized, double-blinded, placebo-controlled pilot study.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty; Arthroscopy; Blood Loss, Surgica

2020
The effect of intravenous tranexamic acid on visual clarity during arthroscopic rotator cuff repair: A randomized, double-blinded, placebo-controlled pilot study.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty; Arthroscopy; Blood Loss, Surgica

2020
The effect of intravenous tranexamic acid on visual clarity during arthroscopic rotator cuff repair: A randomized, double-blinded, placebo-controlled pilot study.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty; Arthroscopy; Blood Loss, Surgica

2020
Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study).
    BMJ open, 2021, 01-17, Volume: 11, Issue:1

    Topics: Administration, Intravenous; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio

2021
Comparison of Effects of a Thrombin-Based Hemostatic Agent and Topical Tranexamic Acid on Blood Loss in Patients with Preexisting Thromboembolic Risk Undergoing a Minimally Invasive Total Knee Arthroplasty. A Prospective Randomized Controlled Trial.
    BioMed research international, 2021, Volume: 2021

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2021
Effects of tourniquet use on clinical outcomes and cement penetration in TKA when tranexamic acid administrated: a randomized controlled trial.
    BMC musculoskeletal disorders, 2021, Jan-31, Volume: 22, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Bone Cements; Humans

2021
Outcomes of combined use of topical and intravenous tranexamic acid on surgical field quality during functional endoscopic sinus surgery: Randomized controlled trial.
    Head & neck, 2021, Volume: 43, Issue:5

    Topics: Administration, Intravenous; Blood Loss, Surgical; Endoscopy; Humans; Prospective Studies; Tranexami

2021
Tranexamic acid in joint replacement : a randomized trial comparing intravenous oral and topical routes.
    Acta orthopaedica Belgica, 2020, Volume: 86, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Aged, 80 and over;

2020
Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial.
    BJU international, 2022, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Vol

2022
Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial.
    BJU international, 2022, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Vol

2022
Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial.
    BJU international, 2022, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Vol

2022
Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double-blinded, placebo-controlled trial.
    BJU international, 2022, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Vol

2022
Prospective, randomised, controlled study on the efficacy and safety of different strategies of tranexamic acid with total blood loss, blood transfusion rate and thrombogenic biomarkers in total knee arthroplasty: study protocol.
    BMJ open, 2021, 02-26, Volume: 11, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2021
Infographic: Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial.
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Bl

2021
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial.
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; F

2021
[Clinical effects of tranexamic acid in arthroscope for femoroacetabular impingement].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2021, Feb-25, Volume: 34, Issue:2

    Topics: Adult; Aged; Arthroscopes; Arthroscopy; Blood Loss, Surgical; Female; Femoracetabular Impingement; H

2021
Are The Applications of Tranexamic Acid in Reverse Hybrid Total Knee Arthroplasty (TKA) The Same as Those in Fully Cemented TKA?: A Randomized Controlled Trial.
    Advances in therapy, 2021, Volume: 38, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
Tranexamic Acid in Pediatric Scoliosis Surgery: A Prospective Randomized Trial Comparing High-dose and Low-dose Tranexamic Acid in Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion Surgery.
    Spine, 2021, Nov-15, Volume: 46, Issue:22

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Humans; Prospective Studies

2021
Multiple intravenous tranexamic acid doses in total knee arthroplasty in patients with rheumatoid arthritis: a randomized controlled study.
    BMC musculoskeletal disorders, 2021, May-07, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Rep

2021
Intravenous tranexamic acid reduce postoperative drainage and pain after open elbow arthrolysis: a randomized controlled trial.
    Journal of shoulder and elbow surgery, 2021, Volume: 30, Issue:8

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Drainage; Elbow; Humans;

2021
[Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss after intramedullary fixation of intertrochanteric femoral fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, May-15, Volume: 35, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Blood Loss, Surgical; Bone Nails; Femoral Frac

2021
Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total hip arthroplasty: results of a randomized controlled trial (TRAC-24).
    The bone & joint journal, 2021, Volume: 103-B, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthropla

2021
Oral Is as Effective as Intravenous Tranexamic Acid at Reducing Blood Loss in Thoracolumbar Spinal Fusions: A Prospective Randomized Trial.
    Spine, 2022, Jan-15, Volume: 47, Issue:2

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Ma

2022
Evaluation of local tranexamic acid on septoplastic surgery quality.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2021, Volume: 74, Issue:10

    Topics: Administration, Topical; Antifibrinolytic Agents; Arterial Pressure; Attitude of Health Personnel; B

2021
The Effects of Tranexamic Acid on Bleeding Control During and after Percutaneous Nephrolithotomy (PCNL): A Randomized Clinical Trial.
    Urology journal, 2021, 07-22, Volume: 18, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Humans; Nephr

2021
Use of tranexamic acid does not influence perioperative outcomes in ambulatory foot and ankle surgery-a prospective triple blinded randomized controlled trial.
    International orthopaedics, 2021, Volume: 45, Issue:9

    Topics: Ankle; Antifibrinolytic Agents; Blood Loss, Surgical; Foot; Humans; Prospective Studies; Tranexamic

2021
Efficacy and Safety of Tranexamic Acid for the Control of Surgical Bleeding in Patients Under Liposuction.
    Aesthetic plastic surgery, 2022, Volume: 46, Issue:1

    Topics: Blood Loss, Surgical; Humans; Lipectomy; Prospective Studies; Tranexamic Acid; Treatment Outcome

2022
Combined topical and intravenous administration of tranexamic acid further reduces postoperative blood loss in adolescent idiopathic scoliosis patients undergoing spinal fusion surgery: a randomized controlled trial.
    BMC musculoskeletal disorders, 2021, Aug-09, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Adolescent; Antifibrinolytic Agents; Blood Los

2021
Tranexamic acid in a periarticular multimodal cocktail injection for blood management in total knee arthroplasty: a prospective randomized study.
    BMC musculoskeletal disorders, 2021, Aug-10, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2021
Topical tranexamic acid in hip fractures: a randomized, placebo-controlled double-blinded study.
    Canadian journal of surgery. Journal canadien de chirurgie, 2021, 08-10, Volume: 64, Issue:4

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2021
Tranexamic acid attenuates early post-operative systemic inflammatory response and nutritional loss and avoids reduction of fibrinogen in total hip arthroplasty within an enhanced recovery after surgery pathway.
    International orthopaedics, 2021, Volume: 45, Issue:11

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Enhanced Recovery Aft

2021
Effectiveness of preoperative tranexamic acid in reducing blood loss during caesarean section at Aminu Kano Teaching Hospital, Kano: a randomized controlled trial.
    The Pan African medical journal, 2021, Volume: 39

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2021
Cost-Benefit Analysis of Using A Single Dose of Tranexamic Acid in Degenerative Lumbar Scoliosis Patients Undergoing Long-Segment Spinal Fusion Surgery: A Retrospective Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Aug-23, Volume: 27

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Clinical Decision-Making; Combined Modality The

2021
Effectiveness of tranexamic acid for reducing intraoperative bleeding in palatoplasties: A randomized clinical trial.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2017, Volume: 45, Issue:5

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Cleft Palate; Do

2017
Determination of Perioperative Blood Loss: Accuracy or Approximation?
    Anesthesia and analgesia, 2017, Volume: 125, Issue:1

    Topics: Algorithms; Anthropometry; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surg

2017
Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2017, Volume: 45, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Ecchymosis; Edema; Female

2017
Tranexamic Acid Reduces Occult Blood Loss, Blood Transfusion, and Improves Recovery of Knee Function after Total Knee Arthroplasty: A Comparative Study.
    The journal of knee surgery, 2018, Volume: 31, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; F

2018
A comparative analysis of the role of Tranexamic acid as an independent variable in reducing intraoperative blood loss in patients undergoing conventional total knee arthroplasty versus computer-assisted total knee arthroplasty.
    Musculoskeletal surgery, 2017, Volume: 101, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Hemogl

2017
Tranexamic Acid Safely Reduced Blood Loss in Hemi- and Total Hip Arthroplasty for Acute Femoral Neck Fracture: A Randomized Clinical Trial.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2017
Tranexamic Acid in Knee Surgery Study-A Multicentered, Randomized, Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:11

    Topics: Aged; Anesthetics; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; C

2017
Effectiveness and Safety of Batroxobin, Tranexamic Acid and a Combination in Reduction of Blood Loss in Lumbar Spinal Fusion Surgery.
    Spine, 2018, 03-01, Volume: 43, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Batroxobin; Blood Loss, Surgical; Blood Transfusion; Double-Bl

2018
Intravenous Tranexamic Acid Bolus plus Infusion Is Not More Effective than a Single Bolus in Primary Hip Arthroplasty: A Randomized Controlled Trial.
    Anesthesiology, 2017, Volume: 127, Issue:3

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2017
Intra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:11

    Topics: Administration, Intravenous; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee;

2017
The effectiveness of low-dose and high-dose tranexamic acid in posterior lumbar interbody fusion: a double-blinded, placebo-controlled randomized study.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017, Volume: 26, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Middle Aged; Postoperative Hemorrhage;

2017
Comparison of intravenous and intra-articular tranexamic acid in reducing blood loss in primary total knee replacement.
    Eklem hastaliklari ve cerrahisi = Joint diseases & related surgery, 2017, Volume: 28, Issue:2

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2017
The effect of intravenous tranexamic acid on blood loss and early post-operative pain in total shoulder arthroplasty.
    The bone & joint journal, 2017, Volume: 99-B, Issue:8

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2017
Clinical and instrumental evaluation of two different regimens of tranexamic acid in total hip arthroplasty: a single-centre, prospective, randomized study with 80 patients.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Volume; F

2018
Effect of Tranexamic Acid on Transfusion: A Randomized Clinical Trial in Acetabular Fracture Surgery.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Acetabulum; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; F

2017
Blood Conservation Using Tranexamic Acid Is Not Superior to Epsilon-Aminocaproic Acid After Total Knee Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2017, Oct-04, Volume: 99, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacemen

2017
[Safety and efficacy of intravenous tranexamic acid in endoscopic transurethral resections in urology: Prospective randomized trial].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2017, Volume: 27, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cystectomy; Double-Bl

2017
Multiple boluses of intravenous tranexamic acid to reduce hidden blood loss and the inflammatory response following enhanced-recovery primary total hip arthroplasty: a randomised clinical trial.
    The bone & joint journal, 2017, Volume: 99-B, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Biomarkers;

2017
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Oral vs Intravenous vs Topical Tranexamic Acid in Primary Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Administration, Topical; Aged; Antifibrinolytic A

2018
Effects of low-dose epinephrine on perioperative hemostasis and inflammatory reaction in major surgical operations: a randomized clinical trial.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:1

    Topics: Adrenergic Agonists; Adult; Aged; Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, R

2018
A randomized controlled trial on the effects of collagen sponge and topical tranexamic acid in posterior spinal fusion surgeries.
    Journal of orthopaedic surgery and research, 2017, Nov-06, Volume: 12, Issue:1

    Topics: Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusi

2017
The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study.
    International journal of oral and maxillofacial surgery, 2018, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Doubl

2018
A Randomized Controlled Trial of Low-Dose Tranexamic Acid versus Placebo to Reduce Red Blood Cell Transfusion During Complex Multilevel Spine Fusion Surgery.
    World neurosurgery, 2018, Volume: 110

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Erythrocyte Transfusion; F

2018
Tranexamic Acid Decreases Visible and Hidden Blood Loss Without Affecting Prethrombotic State Molecular Markers in Transforaminal Thoracic Interbody Fusion for Treatment of Thoracolumbar Fracture-Dislocation.
    Spine, 2018, 07-01, Volume: 43, Issue:13

    Topics: Adult; Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Double-Blind Method; Female; Fract

2018
Is tranexamic acid exposure related to blood loss in hip arthroplasty? A pharmacokinetic-pharmacodynamic study.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Computer Simula

2018
The Effect of Tranexamic Acid and Gender on Intraoperative Bleeding in Orthognathic Surgery-A Randomized Controlled Trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2018, Volume: 76, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Denmark; Double-Blind Method; Female; Humans;

2018
Intravenous and Topical Tranexamic Acid Alone Are Superior to Tourniquet Use for Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Dec-20, Volume: 99, Issue:24

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; China; Combine

2017
[Comparison of different modes of using tranexamic acid administration on reducing hidden blood loss in total hip arthroplasty].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2016, Aug-25, Volume: 29, Issue:8

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2016
Emergency coronary bypass surgery in patients under the influence of dualantiplatelet therapy: effects of tranexamic acid and desmopressin acetate
    Turkish journal of medical sciences, 2017, Dec-19, Volume: 47, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Deamino Ar

2017
The comparative efficacy and safety of topical and intravenous tranexamic acid for reducing perioperative blood loss in Total knee arthroplasty- A randomized controlled non-inferiority trial.
    The Knee, 2018, Volume: 25, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Synergistic effects of intravenous and intra-articular tranexamic acid on reducing hemoglobin loss in revision total knee arthroplasty: a prospective, randomized, controlled study.
    Transfusion, 2018, Volume: 58, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2018
Topical Tranexamic Acid Reduces Blood Loss in Minimally Invasive Total Knee Arthroplasty Receiving Rivaroxaban.
    BioMed research international, 2017, Volume: 2017

    Topics: Administration, Topical; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2017
The effect of tranexamic acid on hidden bleeding in older intertrochanteric fracture patients treated with PFNA.
    Injury, 2018, Volume: 49, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Fracture Fixation, Intramedullary; Hip

2018
Efficacy and safety of intra-articular versus intravenous tranexamic acid in reducing perioperative blood loss in total knee arthroplasty: a prospective randomized double-blind equivalence trial.
    The bone & joint journal, 2018, Volume: 100-B, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans

2018
The effect of oral versus intravenous tranexamic acid in reducing blood loss after primary total hip arthroplasty: A randomized clinical trial.
    Thrombosis research, 2018, Volume: 164

    Topics: Administration, Intravenous; Administration, Oral; Arthroplasty, Replacement, Hip; Blood Loss, Surgi

2018
Therapeutic and pharmaco-biological, dose-ranging multicentre trial to determine the optimal dose of TRAnexamic acid to reduce blood loss in haemorrhagic CESarean delivery (TRACES): study protocol for a randomised, double-blind, placebo-controlled trial.
    Trials, 2018, Mar-01, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Dr

2018
TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial.
    Trials, 2018, Mar-01, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Dr

2018
TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial.
    Trials, 2018, Mar-01, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Dr

2018
TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial.
    Trials, 2018, Mar-01, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Dr

2018
TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial.
    Trials, 2018, Mar-01, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Dr

2018
Efficacy of oral tranexamic acid on blood loss in primary total hip arthroplasty using a direct anterior approach: a prospective randomized controlled trial.
    International orthopaedics, 2018, Volume: 42, Issue:11

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2018
Efficacy and safety of topical tranexamic acid in knee arthroplasty.
    Medicina clinica, 2018, 12-14, Volume: 151, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Comparison of oral versus intra-articular tranexamic acid in enhanced-recovery primary total knee arthroplasty without tourniquet application: a randomized controlled trial.
    BMC musculoskeletal disorders, 2018, 03-15, Volume: 19, Issue:1

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2018
Comparison between Intravenous Boluses versus Infusion of Tranexamic Acid (TXA) to Reduce Bleeding in Paediatric Cyanotic Congenital Heart Disease (CHD) Surgeries.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:3

    Topics: Administration, Intravenous; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cardi

2018
Comparing the efficacy of intravenous or intra-articular tranexamic acid in reducing blood loss in simultaneous bilateral knee replacement surgery without the use of tourniquet.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2018
The efficacy and safety of multiple-dose oral tranexamic acid on blood loss following total hip arthroplasty: a randomized controlled trial.
    International orthopaedics, 2019, Volume: 43, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2019
Use of Tranexamic Acid to Reduce Blood Loss in Liposuction.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:5

    Topics: Adult; Blood Loss, Surgical; Double-Blind Method; Female; Hematocrit; Humans; Injections, Intravenou

2018
Tranexamic Acid versus Placebo to Prevent Blood Transfusion during Radical Cystectomy for Bladder Cancer (TACT): Study Protocol for a Randomized Controlled Trial.
    Trials, 2018, May-02, Volume: 19, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Canada; Cystectomy; Double-Blind M

2018
Multiple-Dose Intravenous Tranexamic Acid Further Reduces Hidden Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:9

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2018
Tranexamic acid use during total hip arthroplasty: A single center retrospective analysis.
    Medicine, 2018, Volume: 97, Issue:21

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2018
Comparison of intravenous and topical tranexamic acid in total knee arthroplasty.
    BMC musculoskeletal disorders, 2018, Jun-13, Volume: 19, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Intravenous Versus Topical Tranexamic Acid in Total Knee Arthroplasty: Both Effective in a Randomized Clinical Trial of 640 Patients.
    The Journal of bone and joint surgery. American volume, 2018, Jun-20, Volume: 100, Issue:12

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Re-evaluation of the efficacy of tranexamic acid in reducing blood loss in percutaneous nephrolithotomy: a randomized clinical trial.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2019, Volume: 71, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Infus

2019
OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2019, Volume: 29, Issue:3

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Doubl

2019
Blood-conserving efficacy of multiple doses of oral tranexamic acid associated with an enhanced-recovery programme in primary total knee arthroplasty: a randomized controlled trial.
    The bone & joint journal, 2018, Volume: 100-B, Issue:8

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2018
Assessment of the effect of addition of 24 hours of oral tranexamic acid post-operatively to a single intraoperative intravenous dose of tranexamic acid on calculated blood loss following primary hip and knee arthroplasty (TRAC-24): a study protocol for a
    Trials, 2018, Jul-31, Volume: 19, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthropla

2018
Efficacy of topical tranexamic acid within a blood-saving programme for primary total hip arthroplasty: a pragmatic, open-label randomised study.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:6

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2018
Tranexamic acid in primary total knee arthroplasty without tourniquet: a randomized, controlled trial of oral versus intravenous versus topical administration.
    Scientific reports, 2018, 09-11, Volume: 8, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthritis, Rheumat

2018
Similar thromboprophylaxis with rivaroxaban and low molecular weight heparin but fewer hemorrhagic complications with combined intra-articular and intravenous tranexamic acid in total knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2019, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Knee; Blood Loss, Surgica

2019
Comparative Efficacy of Intravenous With Intra-articular Versus Intravenous Only Administration of Tranexamic Acid to Reduce Blood Loss in Knee Arthroplasty.
    Orthopedics, 2018, Nov-01, Volume: 41, Issue:6

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2018
Is topical or intravenous tranexamic acid preferred in total hip arthroplasty? A randomized, controlled, noninferiority clinical trial.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2018
Using intra-articular tranexamic acid in total knee replacement surgery with and without bleeding control: a prospective randomized double blind study.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:18

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2018
Blood loss and cost-effectiveness of oral vs intravenous tranexamic acid in primary total hip arthroplasty: A randomized clinical trial.
    Thrombosis research, 2018, Volume: 171

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2018
Intravenous Administration of Tranexamic Acid Significantly Reduces Visible and Hidden Blood Loss Compared with Its Topical Administration for Double-Segment Posterior Lumbar Interbody Fusion: A Single-Center, Placebo-Controlled, Randomized Trial.
    World neurosurgery, 2019, Volume: 122

    Topics: Administration, Intravenous; Administration, Topical; Adult; Antifibrinolytic Agents; Blood Loss, Su

2019
Bilateral uterine artery ligation plus intravenous tranexamic acid during cesarean delivery for placenta previa: a randomized double-blind controlled trial.
    Journal of gynecology obstetrics and human reproduction, 2019, Volume: 48, Issue:2

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2019
[Comparison of combined intravenous and topical use of tranexamic acid with different dosage in primary total knee arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2018, 11-15, Volume: 32, Issue:11

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2018
The antifibrinolytic and anti-inflammatory effects of multiple doses of oral tranexamic acid in total knee arthroplasty patients: a randomized controlled trial.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:12

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replace

2018
Subcutaneous tranexamic acid in upper eyelid blepharoplasty: a prospective randomized pilot study.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2018, Volume: 53, Issue:6

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blepharoplasty; Blood Loss, Surgical; Chalazion; D

2018
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2018, Dec-05, Volume: 100, Issue:23

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F

2018
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2018, Dec-05, Volume: 100, Issue:23

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F

2018
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2018, Dec-05, Volume: 100, Issue:23

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F

2018
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2018, Dec-05, Volume: 100, Issue:23

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; F

2018
Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study).
    Archives of orthopaedic and trauma surgery, 2019, Volume: 139, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2019
Intravenous and Oral Tranexamic Acid Are Equivalent at Reducing Blood Loss in Thoracolumbar Spinal Fusion: A Prospective Randomized Trial.
    Spine, 2019, Jun-01, Volume: 44, Issue:11

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Blood Loss, Surgic

2019
Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial.
    Thrombosis and haemostasis, 2019, Volume: 119, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2019
Subcutaneous Injection of Tranexamic Acid to Reduce Bleeding During Dermatologic Surgery: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2019, Volume: 45, Issue:6

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dermatologic Surgical Proced

2019
A randomized, double-blind, placebo-controlled trial on the efficacy of tranexamic acid combined with rivaroxaban thromboprophylaxis in reducing blood loss after primary cementless total hip arthroplasty.
    The bone & joint journal, 2019, Volume: 101-B, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2019
Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries (TARGETS): study protocol for a prospective, randomized, double-blind, non-inferiority trial.
    Trials, 2019, Feb-12, Volume: 20, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Data Interpretation, Statistical;

2019
Intra-Articular Tranexamic Acid Mitigates Blood Loss and Morphine Use After Total Knee Arthroplasty. A Randomized Controlled Trial.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:5

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2019
Combined intravenous and intra-articular tranexamic acid administration in total knee arthroplasty for preventing blood loss and hyperfibrinolysis: A randomized controlled trial.
    Medicine, 2019, Volume: 98, Issue:7

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty,

2019
The efficacy and safety of multiple doses of oral tranexamic acid on blood loss, inflammatory and fibrinolysis response following total knee arthroplasty: A randomized controlled trial.
    International journal of surgery (London, England), 2019, Volume: 65

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Double-Blind M

2019
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study.
    Journal of cardiac surgery, 2019, Volume: 34, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aortic Valve; Blood Loss, Surgical; Cardiac

2019
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study.
    Journal of cardiac surgery, 2019, Volume: 34, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aortic Valve; Blood Loss, Surgical; Cardiac

2019
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study.
    Journal of cardiac surgery, 2019, Volume: 34, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aortic Valve; Blood Loss, Surgical; Cardiac

2019
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study.
    Journal of cardiac surgery, 2019, Volume: 34, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Aortic Valve; Blood Loss, Surgical; Cardiac

2019
Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2019, Volume: 25, Issue:2

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical;

2019
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled Trial.
    Journal of orthopaedic trauma, 2019, Volume: 33, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Femoral Fractures;

2019
Reduced perioperative blood loss in children undergoing craniosynostosis surgery using prolonged tranexamic acid infusion: a randomised trial.
    British journal of anaesthesia, 2019, Volume: 122, Issue:6

    Topics: Anesthesia, General; Antifibrinolytic Agents; Blood Loss, Surgical; Child, Preschool; Craniosynostos

2019
The combined administration of systemic and topical tranexamic acid for total hip arthroplasty: Is it better than systemic?
    Acta orthopaedica et traumatologica turcica, 2019, Volume: 53, Issue:4

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2019
Cost-benefit analysis of the use of tranexamic acid in total replacement hip surgery.
    Journal of clinical anesthesia, 2019, Volume: 57

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2019
Blood loss reduction: effect of different knee prosthesis designs and use of tranexamic acid-a randomized controlled trial.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2019, Volume: 29, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2019
2019 Mark Coventry Award: A multicentre randomized clinical trial of tranexamic acid in revision total knee arthroplasty: does the dosing regimen matter?.
    The bone & joint journal, 2019, Volume: 101-B, Issue:7_Supple_C

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administration

2019
Intra-Articular Injection of Tranexamic Acid on Perioperative Blood Loss During Unicompartmental Knee Arthroplasty.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Jul-09, Volume: 25

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2019
Multi-route applications of tranexamic acid to reduce blood loss after total knee arthroplasty: a randomized controlled trial.
    Medicine, 2019, Volume: 98, Issue:30

    Topics: Age Factors; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; B

2019
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial.
    JAMA surgery, 2013, Volume: 148, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Clopidogr

2013
Tranexamic acid without prophylactic factor replacement for prevention of bleeding in hereditary bleeding disorder patients undergoing endoscopy: a pilot study.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2013, Volume: 19, Issue:4

    Topics: Adult; Aged; Biopsy; Blood Coagulation Factors; Blood Loss, Surgical; Demography; Endoscopy; Female;

2013
Effectiveness of tranexamic acid on blood loss in patients undergoing elective cesarean section: randomized clinical trial.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:17

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Elective Surgical Procedures

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid in decreasing blood loss during and after caesarean section.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Comparison of two doses of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass.
    Anesthesiology, 2014, Volume: 120, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Platelets; Blood Transfusion; Cardiac Sur

2014
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
A prospective double-blind placebo controlled trial of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Effect of tranexamic acid on reducing postoperative blood loss in combined hypotensive epidural anesthesia and general anesthesia for total hip replacement.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement

2013
Comparison of epsilon aminocaproic acid and tranexamic Acid in thoracic aortic surgery: clinical efficacy and safety.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Aorta, Thoracic; Blood Loss, Surgical; Blood Tran

2013
Effectiveness of oral Tranexamic acid administration on blood loss after knee artroplasty: a randomized clinical trial.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2013, Volume: 49, Issue:3

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2013
The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty.
    Annals of plastic surgery, 2015, Volume: 74, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration

2015
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).
    The Journal of bone and joint surgery. American volume, 2013, Nov-06, Volume: 95, Issue:21

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2013
Topical administration of tranexamic acid in primary total hip and total knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty

2014
Continuous or discontinuous tranexamic acid effectively inhibits fibrinolysis in children undergoing cardiac surgery with cardiopulmonary bypass.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2014, Volume: 25, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass;

2014
Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study.
    Acta obstetricia et gynecologica Scandinavica, 2014, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2014
Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study.
    Acta obstetricia et gynecologica Scandinavica, 2014, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2014
Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study.
    Acta obstetricia et gynecologica Scandinavica, 2014, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2014
Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study.
    Acta obstetricia et gynecologica Scandinavica, 2014, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2014
Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: a randomised, controlled study.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiopulmonary Bypass; Dose

2014
Tranexamic acid used before caesarean section reduces blood loss based on pre- and postoperative haemoglobin level: a case-control study.
    Journal of the Indian Medical Association, 2013, Volume: 111, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Cesarean Section; Female

2013
Comparing efficacy of three methods of tranexamic acid administration in reducing hemoglobin drop following total knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2014
Comparison of intravenous versus topical tranexamic acid in total knee arthroplasty: a prospective randomized study.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2014
Comparison of intravenous versus topical tranexamic acid in total knee arthroplasty: a prospective randomized study.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2014
Comparison of intravenous versus topical tranexamic acid in total knee arthroplasty: a prospective randomized study.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2014
Comparison of intravenous versus topical tranexamic acid in total knee arthroplasty: a prospective randomized study.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2014
Effectiveness of tranexamic acid on intraoperative blood loss in isolated Le Fort I osteotomies--a prospective, triple blinded randomized clinical trial.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2014, Volume: 42, Issue:7

    Topics: Adolescent; Adult; Anesthesia, General; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemat

2014
Comparison between intravenous and intra-articular regimens of tranexamic acid in reducing blood loss during total knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2014
The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trial.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

2015
The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial.
    The Journal of bone and joint surgery. American volume, 2014, May-21, Volume: 96, Issue:10

    Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Dou

2014
Weighted versus uniform dose of tranexamic acid in patients undergoing primary, elective knee arthroplasty: a prospective randomized controlled trial.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:9 Suppl

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood T

2014
Weighted versus uniform dose of tranexamic acid in patients undergoing primary, elective knee arthroplasty: a prospective randomized controlled trial.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:9 Suppl

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood T

2014
Weighted versus uniform dose of tranexamic acid in patients undergoing primary, elective knee arthroplasty: a prospective randomized controlled trial.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:9 Suppl

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood T

2014
Weighted versus uniform dose of tranexamic acid in patients undergoing primary, elective knee arthroplasty: a prospective randomized controlled trial.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:9 Suppl

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood T

2014
[Effect of priming solution and ultrafiltration on post-operative bleeding and blood transfusion in cardiac surgery. Randomized controlled trial].
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:2

    Topics: Aged; Aged, 80 and over; Albumins; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusion;

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Efficacy of tranexamic acid in decreasing blood loss in elective caesarean delivery.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Pregnancy; P

2015
Effect of topical tranexamic acid on bleeding and quality of surgical field during functional endoscopic sinus surgery in patients with chronic rhinosinusitis: a triple blind randomized clinical trial.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Chronic D

2014
Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2014
Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2014
Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2014
Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2014
Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2015, Volume: 73, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Bl

2015
Preliminary investigation of high-dose tranexamic acid for controlling intraoperative blood loss in patients undergoing spine correction surgery.
    The spine journal : official journal of the North American Spine Society, 2015, Apr-01, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Female; Humans; Male; Middl

2015
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.
    The Journal of bone and joint surgery. American volume, 2014, Dec-03, Volume: 96, Issue:23

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2014
Evaluation of the Efficacy of Tranexamic Acid on the Surgical Field in Primary Cleft Palate Surgery on Children-A Prospective, Randomized Clinical Study.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2015, Volume: 52, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child, Preschool; Cleft Palate; Double-Blind Method;

2015
The efficacy of combined use of intraarticular and intravenous tranexamic acid on reducing blood loss and transfusion rate in total knee arthroplasty.
    The Journal of arthroplasty, 2015, Volume: 30, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agen

2015
Reducing blood loss in simultaneous bilateral total knee arthroplasty: combined intravenous-intra-articular tranexamic acid administration. A prospective randomized controlled trial.
    The Knee, 2015, Volume: 22, Issue:2

    Topics: Aged; Analgesics; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Do

2015
Effectiveness and safety of tranexamic acid for total knee arthroplasty: a prospective randomized controlled trial.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Feb-22, Volume: 21

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies; Demography; Femal

2015
Topical application of tranexamic acid reduces postoperative bleeding in open-heart surgery: myth or fact?
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:3

    Topics: Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgica

2015
Antifibrinolytics reduce blood loss in adult spinal deformity surgery: a prospective, randomized controlled trial.
    Spine, 2015, Apr-15, Volume: 40, Issue:8

    Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Vo

2015
Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial.
    Archives of orthopaedic and trauma surgery, 2015, Volume: 135, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replaceme

2015
Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial.
    Archives of orthopaedic and trauma surgery, 2015, Volume: 135, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replaceme

2015
Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial.
    Archives of orthopaedic and trauma surgery, 2015, Volume: 135, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replaceme

2015
Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial.
    Archives of orthopaedic and trauma surgery, 2015, Volume: 135, Issue:7

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replaceme

2015
Safety and efficacy of intra-articular tranexamic acid injection without drainage on blood loss in total knee arthroplasty: A randomized clinical trial.
    International journal of surgery (London, England), 2015, Volume: 20

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2015
A regime of two intravenous injections of tranexamic acid reduces blood loss in minimally invasive total hip arthroplasty: a prospective randomised double-blind study.
    The bone & joint journal, 2015, Volume: 97-B, Issue:7

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2015
Intra-articular injection of tranexamic acid reduce blood loss in cemented total knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2015
Two Doses of Tranexamic Acid Reduce Blood Transfusion in Complex Spine Surgery: A Prospective Randomized Study.
    Spine, 2015, Volume: 40, Issue:24

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2015
Comparison of pterygomaxillary dysjunction with tuberosity separation in isolated Le Fort I osteotomies: a prospective, multi-centre, triple-blind, randomized controlled trial.
    International journal of oral and maxillofacial surgery, 2016, Volume: 45, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Maxillofacial Abnormalit

2016
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2015
[A PROSPECTIVE RANDOMIZED SELF-CONTROLLED STUDY ON EFFECT OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS IN TOTAL KNEE ARTHROPLASTY].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2015, Volume: 29, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2015
Neer Award 2015: A randomized, prospective evaluation on the effectiveness of tranexamic acid in reducing blood loss after total shoulder arthroplasty.
    Journal of shoulder and elbow surgery, 2015, Volume: 24, Issue:11

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement

2015
[Is intraarticular administration of tranexamic acid efficient and safe as systemic administration in total knee arthroplasty? Single center, randomized, controlled trial].
    Eklem hastaliklari ve cerrahisi = Joint diseases & related surgery, 2015, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2015
The effect of tranexamic acid on blood coagulation in total hip replacement arthroplasty: rotational thromboelastographic (ROTEM®) analysis.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagu

2016
The effect of tranexamic acid on blood coagulation in total hip replacement arthroplasty: rotational thromboelastographic (ROTEM®) analysis.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagu

2016
The effect of tranexamic acid on blood coagulation in total hip replacement arthroplasty: rotational thromboelastographic (ROTEM®) analysis.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagu

2016
The effect of tranexamic acid on blood coagulation in total hip replacement arthroplasty: rotational thromboelastographic (ROTEM®) analysis.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagu

2016
The Efficacy of Preoperative Oral Tranexamic Acid on Intraoperative Bleeding During Rhinoplasty.
    The Journal of craniofacial surgery, 2016, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Me

2016
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Efficacy of Tranexamic Acid on Myomectomy-Associated Blood Loss in Patients With Multiple Myomas: A Randomized Controlled Clinical Trial.
    Reproductive sciences (Thousand Oaks, Calif.), 2016, Volume: 23, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Leiomyoma; Prospective Studies

2016
Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: A double-blinded randomised controlled noninferiority trial.
    The Knee, 2016, Volume: 23, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2016
[The Effect of Tranexamic Acid on Blood Loss after Primary Unilateral Total Knee Arthroplasty. Prospective Single-Centre Study].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2015, Volume: 82, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2015
A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty.
    British journal of anaesthesia, 2016, Volume: 116, Issue:3

    Topics: Adrenergic alpha-Agonists; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coag

2016
Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy-a double-blinded randomized placebo-controlled trial.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2016
Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy-a double-blinded randomized placebo-controlled trial.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2016
Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy-a double-blinded randomized placebo-controlled trial.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2016
Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy-a double-blinded randomized placebo-controlled trial.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method;

2016
Topical vs Intravenous Tranexamic Acid in Reducing Blood Loss After Bilateral Total Knee Arthroplasty: A Prospective Study.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:7

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2016
Tranexamic Acid Reduces Hidden Blood Loss in Patients Undergoing Total Knee Arthroplasty: A Comparative Study and Meta-Analysis.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Mar-10, Volume: 22

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; B

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Efficacy of Local Administration of Tranexamic Acid for Blood Salvage in Patients Undergoing Intertrochanteric Fracture Surgery.
    Journal of orthopaedic trauma, 2016, Volume: 30, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Dou

2016
Tranexamic Acid Compared with Placebo for Reducing Total Blood Loss in Hip Replacement Surgery: A Randomized Clinical Trial.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses.
    Thrombosis research, 2016, Volume: 141

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood

2016
Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Aspirin; Bl

2016
Effect of Topical and Intravenously Applied Tranexamic Acid Compared to Control Group on Bleeding in Primary Unilateral Total Knee Arthroplasty.
    The journal of knee surgery, 2017, Volume: 30, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2017
What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?
    Der Orthopade, 2016, Volume: 45, Issue:7

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Dose-Response

2016
Effectiveness and Safety of Fixed-Dose Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Randomized Double-Blind Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
The Efficacy and Safety of Combination of Intravenous and Topical Tranexamic Acid in Revision Hip Arthroplasty: A Randomized, Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Animals; Antifibrinolytic Agents; Arthro

2016
Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2016, May-18, Volume: 98, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2016, May-18, Volume: 98, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2016, May-18, Volume: 98, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2016, May-18, Volume: 98, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
Tranexamic acid reduces blood loss in patients with extracapsular fractures of the hip: results of a randomised controlled trial.
    The bone & joint journal, 2016, Volume: 98-B, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark; Double-Blind Method

2016
The Assessment of Blood Loss During Total Knee Arthroplasty When Comparing Intravenous vs Intracapsular Administration of Tranexamic Acid.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2016
Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomark

2016
Intravenous vs Topical Tranexamic Acid in Total Knee Arthroplasty Without Tourniquet Application: A Randomized Controlled Study.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2016
Dual-route tranexamic acid to reduce blood loss in coronary artery bypass graft surgery: a randomized controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:9

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Critical Care; Double-B

2016
Efficacy of preoperative administration of single high dose intravenous tranexamic acid in reducing blood loss in total knee arthroplasty: A prospective clinical study.
    Acta orthopaedica et traumatologica turcica, 2016, Volume: 50, Issue:4

    Topics: Administration, Intravenous; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Tran

2016
Intravenous vs Intra-Articular Tranexamic Acid in Total Knee Arthroplasty: A Randomized, Double-Blind Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
Combined Administration of IV and Topical Tranexamic Acid is Not Superior to Either Individually in Primary Navigated TKA.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2017
Efficacy of Hybrid Plasma Scalpel in Reducing Blood Loss and Transfusions in Direct Anterior Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2017
The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2017
Major liver resection, systemic fibrinolytic activity, and the impact of tranexamic acid.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2016, Volume: 18, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Drug Monitoring; Female; Fibrinolys

2016
Efficacy of a Single Dose and an Additional Dose of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
Optimizing effectivity of tranexamic acid in bilateral knee arthroplasty - A prospective randomized controlled study.
    The Knee, 2017, Volume: 24, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2017
A double-blind, placebo-controlled randomized clinical trial to evaluate the efficacy of tranexamic acid in irrigant solution on blood loss during percutaneous nephrolithotomy: a pilot study from tertiary care center of North India.
    World journal of urology, 2017, Volume: 35, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female

2017
Use of tranexamic acid in dynamic hip screw plate fixation for trochanteric fractures.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:3

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bone Plates; Bone Scr

2016
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial.
    Medicine, 2017, Volume: 96, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Decompression, Surgical; Double-Blind Me

2017
OBTAIN A: Outcome Benefits of Tranexamic Acid in Hip Arthroplasty. A Randomized Double-Blinded Controlled Trial.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2017
Intravenous Combined with Topical Administration of Tranexamic Acid in Primary Total Hip Arthroplasty: A Randomized Controlled Trial.
    Orthopaedic surgery, 2017, Volume: 9, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthro

2017
Effects of five treatment regimens on blood loss and blood transfusion in total knee arthroplasty: a preliminary study in China
.
    International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:5

    Topics: Aged; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Lo

2017
Intravenous tranexamic acid reduces total blood loss in reverse total shoulder arthroplasty: a prospective, double-blinded, randomized, controlled trial.
    Journal of shoulder and elbow surgery, 2017, Volume: 26, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Tran

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
Intraoperative tranexamic acid use in major spine surgery in adults: a multicentre, randomized, placebo-controlled trial†.
    British journal of anaesthesia, 2017, Mar-01, Volume: 118, Issue:3

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Bl

2017
Clamping drainage is unnecessary after minimally invasive total knee arthroplasty in patients with tranexamic acid: A randomized, controlled trial.
    Medicine, 2017, Volume: 96, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Constriction;

2017
Aprotinin vs. tranexamic acid in isolated coronary artery bypass surgery: A multicentre observational study.
    European journal of anaesthesiology, 2017, Volume: 34, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Coronary Artery Bypass; Female; Hemo

2017
A randomized control trial to evaluate the effectiveness of intravenous, intra-articular and topical wash regimes of tranexamic acid in primary total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2017, Volume: 25, Issue:1

    Topics: Accidental Falls; Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacem

2017
Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Mar-01, Volume: 99, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2017
Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Mar-01, Volume: 99, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2017
Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Mar-01, Volume: 99, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2017
Oral and Intravenous Tranexamic Acid Are Equivalent at Reducing Blood Loss Following Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of bone and joint surgery. American volume, 2017, Mar-01, Volume: 99, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2017
Pharmacokinetics of tranexamic acid in neonates and infants undergoing cardiac surgery.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:8

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedu

2017
Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Adolescent; Animals; Blood Loss, Surgical; Female; Humans; Male; Nociception; Pain; Rats; Scoliosis;

2017
Effect of tranexamic acid on intraoperative blood loss and transfusion requirements in patients undergoing excision of intracranial meningioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 41

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemostasis, Surgica

2017
Effect of tranexamic acid on intraoperative blood loss and transfusion requirements in patients undergoing excision of intracranial meningioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 41

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemostasis, Surgica

2017
Effect of tranexamic acid on intraoperative blood loss and transfusion requirements in patients undergoing excision of intracranial meningioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 41

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemostasis, Surgica

2017
Effect of tranexamic acid on intraoperative blood loss and transfusion requirements in patients undergoing excision of intracranial meningioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 41

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemostasis, Surgica

2017
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Bloo

2008
Tranexamic Acid reduces perioperative blood loss in adult patients having spinal fusion surgery.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method;

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.
    Spine, 2008, Nov-15, Volume: 33, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2008
The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2009, Volume: 35, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Component Transfusion; Blood Loss, Surgical; Drug Administ

2009
The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:1

    Topics: Adult; Analysis of Variance; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Fem

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2009
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
    British journal of anaesthesia, 2010, Volume: 104, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2010
A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery.
    BMC surgery, 2010, Apr-06, Volume: 10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss,

2010
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study.
    American journal of perinatology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Apgar Score; Birth Weight; Blood Loss, Surgical; Blood Transfusion;

2011
Effects of tranexamic acid on blood loss during total hip arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2010, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2010
Blood conservation strategies for reducing peri-operative blood loss in open heart surgery.
    Mymensingh medical journal : MMJ, 2011, Volume: 20, Issue:1

    Topics: Adult; Aminocaproic Acid; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Female; Huma

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Does tranexamic acid save blood in minimally invasive total knee arthroplasty?
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; H

2011
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study.
    Spine, 2011, Nov-01, Volume: 36, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cervical Vertebrae; F

2011
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study.
    Spine, 2011, Nov-01, Volume: 36, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cervical Vertebrae; F

2011
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study.
    Spine, 2011, Nov-01, Volume: 36, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cervical Vertebrae; F

2011
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study.
    Spine, 2011, Nov-01, Volume: 36, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cervical Vertebrae; F

2011
Intraoperative tranexamic acid reduces blood transfusion in children undergoing craniosynostosis surgery: a randomized double-blind study.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschoo

2011
Intraoperative tranexamic acid reduces blood transfusion in children undergoing craniosynostosis surgery: a randomized double-blind study.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschoo

2011
Intraoperative tranexamic acid reduces blood transfusion in children undergoing craniosynostosis surgery: a randomized double-blind study.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschoo

2011
Intraoperative tranexamic acid reduces blood transfusion in children undergoing craniosynostosis surgery: a randomized double-blind study.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschoo

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschool; Craniosyn

2011
Does tranexamic acid in an irrigating fluid reduce intraoperative blood loss in orthognathic surgery? A double-blind, randomized clinical trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Female; Humans; Male; Max

2011
A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial).
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:5

    Topics: Aged; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double-Blind Method

2012
Reducing blood loss in primary knee arthroplasty: a prospective randomised controlled trial of tranexamic acid and fibrin spray.
    The Knee, 2012, Volume: 19, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fibrin; Fibrinogen;

2012
Efficacy of prophylactic low dose of tranexamic acid in spinal fixation surgery: a randomized clinical trial.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Antifibrinolytic Agents; Blood Cell Count;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Effect of intravenous tranexamic acid administration on blood loss during and after cesarean delivery.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2011
Which is more effective in adolescent idiopathic scoliosis surgery: batroxobin, tranexamic acid or a combination?
    Archives of orthopaedic and trauma surgery, 2012, Volume: 132, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Batroxobin; Blood Loss, Surgical; Blood Transfusion; Drainage;

2012
Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Adolescent; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child,

2011
Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Adolescent; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child,

2011
Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Adolescent; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child,

2011
Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Adolescent; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Child,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray.
    Acta orthopaedica, 2011, Volume: 82, Issue:6

    Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial.
    BMJ (Clinical research ed.), 2011, Oct-19, Volume: 343

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Follow

2011
Effect of tranexamic acid on transfusion requirement in dual antiplatelet-treated anemic patients undergoing off-pump coronary artery bypass graft surgery.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:1

    Topics: Aged; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Comorbidity; Coronar

2012
The effect of intravenous tranexamic acid on blood loss and surgical field quality during endoscopic sinus surgery: a placebo-controlled clinical trial.
    Journal of clinical anesthesia, 2011, Volume: 23, Issue:8

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Endoscopy; Female; Hospit

2011
Evaluation of the efficacy of tranexamic acid on blood loss in orthognathic surgery. A prospective, randomized clinical study.
    International journal of oral and maxillofacial surgery, 2012, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Tra

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:9

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Bl

2012
Tranexamic acid in adenotonsillectomy in children: a double-blind randomized clinical trial.
    International journal of pediatric otorhinolaryngology, 2012, Volume: 76, Issue:10

    Topics: Adenoidectomy; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Double-Blind

2012
The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013, Volume: 21, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Atrial Fibrillation; Blood Loss, Sur

2013
Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2012, Jul-20, Volume: 13

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2012
Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2012, Jul-20, Volume: 13

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2012
Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2012, Jul-20, Volume: 13

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2012
Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial.
    BMC musculoskeletal disorders, 2012, Jul-20, Volume: 13

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2012
Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation.
    Heart, lung & circulation, 2012, Volume: 21, Issue:11

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Dou

2012
Tranexamic Acid in on-pump coronary artery bypass grafting without clopidogrel and aspirin cessation: randomized trial and 1-year follow-up.
    The Annals of thoracic surgery, 2013, Volume: 95, Issue:3

    Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronar

2013
Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013, Volume: 21, Issue:11

    Topics: Aged; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical

2013
Tranexamic acid reduces blood loss during percutaneous nephrolithotomy: a prospective randomized controlled study.
    The Journal of urology, 2013, Volume: 189, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Nephrostomy, Percutaneou

2013
Tranexamic acid for cesarean section: a double-blind, placebo-controlled, randomized clinical trial.
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Double-Blind Method; Female;

2013
Tranexamic acid reduces bleeding and the need for blood transfusion in primary myocardial revascularization.
    The Annals of thoracic surgery, 2002, Volume: 74, Issue:3

    Topics: Aged; Blood Loss, Surgical; Blood Transfusion; Dose-Response Relationship, Drug; Female; Humans; Inf

2002
Tranexamic acid given intraoperatively reduces blood loss after total knee replacement: a randomized, controlled study.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Volume;

2002
Tranexamic acid as a means of reducing the need for blood and blood component therapy in children undergoing open heart surgery for congenital cyanotic heart disease.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85 Suppl 3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Child; Chi

2002
Tranexamic acid reduces bleeding after off-pump coronary artery bypass grafting.
    The Journal of cardiovascular surgery, 2003, Volume: 44, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Female; Humans; Male; Prospec

2003
[Usefulness of tranexamic acid in cranial remodeling surgery].
    Revista espanola de anestesiologia y reanimacion, 2003, Volume: 50, Issue:8

    Topics: Anesthesia Recovery Period; Blood Component Transfusion; Blood Loss, Surgical; Craniosynostoses; Fem

2003
Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized prospective clinical study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2003, Volume: 61, Issue:12

    Topics: Adult; Aged; Anticoagulants; Blood Loss, Surgical; Dental Care for Chronically Ill; Drug Interaction

2003
Tranexamic acid reduces the need for allogenic red blood cell transfusions in patients undergoing total hip replacement.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Cell Count; Blood Loss, Surgica

2004
Tranexamic acid reduces the need for allogenic red blood cell transfusions in patients undergoing total hip replacement.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Cell Count; Blood Loss, Surgica

2004
Tranexamic acid reduces the need for allogenic red blood cell transfusions in patients undergoing total hip replacement.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Cell Count; Blood Loss, Surgica

2004
Tranexamic acid reduces the need for allogenic red blood cell transfusions in patients undergoing total hip replacement.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Cell Count; Blood Loss, Surgica

2004
Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial.
    Current medical research and opinion, 2004, Volume: 20, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass;

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Clinical observation of blood loss reduced by tranexamic acid during and after caesarian section: a multi-center, randomized trial.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Feb-10, Volume: 112, Issue:2

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration

2004
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients.
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2003
Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2004, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Anesthesia, Dental; Blood Loss, Surgical; Combined Modality Therapy; Deamino Argi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Bone bleeding during total hip arthroplasty after administration of tranexamic acid.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2004
Effects of tranexamic acid on postoperative bleeding and related hematochemical variables in coronary surgery: Comparison between on-pump and off-pump techniques.
    The Journal of thoracic and cardiovascular surgery, 2004, Volume: 128, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Biomarkers; Blood Coagulation; Blood Coagulation Tests; Blood Loss, S

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases.
    International orthopaedics, 2004, Volume: 28, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2004
Tranexamic acid in control of primary hemorrhage during transurethral prostatectomy.
    Urology, 2004, Volume: 64, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Intraoperative Period; Male; Middle Age

2004
The postoperative blood-sparing efficacy of oral versus intravenous tranexamic acid after total knee replacement.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2004
Reducing allogeneic transfusion in cardiac surgery: a randomized double-blind placebo-controlled trial of antifibrinolytic therapies used in addition to intra-operative cell salvage.
    British journal of anaesthesia, 2005, Volume: 94, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Tran

2005
Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination?
    Paediatric anaesthesia, 2005, Volume: 15, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Child; Cyanos

2005
[Effects of topical applications of aprotinin and tranexamic acid on blood loss after open heart surgery].
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2005, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgica

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery.
    Anesthesiology, 2005, Volume: 102, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Binding Sites; Blood Coagulation Tests; Blood Loss, Surgical; C

2005
Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty.
    The Journal of bone and joint surgery. American volume, 2005, Volume: 87, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemostatic Tech

2005
The use of tranexamic acid to reduce blood loss during total hip arthroplasty: an observational study.
    Annals of the Royal College of Surgeons of England, 2005, Volume: 87, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Cohort Studies; Femal

2005
[A dose-response study of tranexamic acid. The effect on nausea and blood loss after total knee replacement].
    Ugeskrift for laeger, 2005, Apr-04, Volume: 167, Issue:14

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Dose-Response

2005
Fibrinolytic inhibitors in off-pump coronary surgery: a prospective, randomized, double-blind TAP study (tranexamic acid, aprotinin, placebo).
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2005, Volume: 28, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Coronary Artery Bypass, Off-Pump; Cr

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients.
    Acta orthopaedica, 2005, Volume: 76, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2005
Perioperative parenteral tranexamic acid in liver tumor resection: a prospective randomized trial toward a "blood transfusion"-free hepatectomy.
    Annals of surgery, 2006, Volume: 243, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Chi-Square Distribution; Dou

2006
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis.
    Acta orthopaedica, 2005, Volume: 76, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Double-Blind Me

2005
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2006
Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation.
    Transfusion, 2006, Volume: 46, Issue:4

    Topics: Adult; Aprotinin; Blood Loss, Surgical; Erythrocyte Transfusion; Female; Fibrinolysis; Hemostatics;

2006
Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: a prospective, randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2007, Volume: 89, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2007
Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: a prospective, randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2007, Volume: 89, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2007
Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: a prospective, randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2007, Volume: 89, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2007
Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: a prospective, randomised controlled trial.
    The Journal of bone and joint surgery. British volume, 2007, Volume: 89, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2007
[Effect of tranexamic acid on postoperative bleeding in pediatric heart surgery].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:3

    Topics: Antifibrinolytic Agents; Biomarkers; Blood Loss, Surgical; Blood Proteins; Cardiac Surgical Procedur

2007
Intravenous tranexamic acid use in myomectomy: a prospective randomized double-blind placebo controlled study.
    European journal of obstetrics, gynecology, and reproductive biology, 2008, Volume: 137, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female

2008
Tranexamic acid and primary coronary artery bypass surgery: a prospective study.
    Asian cardiovascular & thoracic annals, 2007, Volume: 15, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Coro

2007
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied.
    Transfusion, 2008, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
[Clinical comparative studies on effect of tranexamic acid on blood loss associated with total knee arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2007, Volume: 21, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Bl

2007
Effectiveness and safety of tranexamic acid administration during total knee arthroplasty.
    Vox sanguinis, 2008, Volume: 95, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2008
[Comparison of effects of aprotinin and tranexamic acid on blood loss in heart surgery].
    Annales francaises d'anesthesie et de reanimation, 1995, Volume: 14, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Blood Loss, Surgical; Blood Tran

1995
[Fibrinolytic inhibitors and prevention of bleeding in cardiac valve surgery. Comparison of tranexamic acid and high dose aprotinin].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Dose-Response Relationship, Drug; D

1995
Comparison of the effects of aprotinin and tranexamic acid on blood loss and related variables after cardiopulmonary bypass.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 108, Issue:6

    Topics: Aged; Analysis of Variance; Aprotinin; Blood Coagulation Tests; Blood Loss, Surgical; Cardiopulmonar

1994
Hemostatic efficacy of dipyridamole, tranexamic acid, and aprotinin in coronary bypass grafting.
    The Annals of thoracic surgery, 1995, Volume: 59, Issue:2

    Topics: Aprotinin; Blood Loss, Surgical; Coronary Artery Bypass; Dipyridamole; Female; Hemoglobins; Hemostas

1995
A comparison of the effects of tranexamic acid and low-dose aprotinin on blood loss and homologous blood usage in patients undergoing cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:3

    Topics: Aged; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cardiac Surgical Procedures;

1995
Prevention of bleeding after cardiopulmonary bypass with high-dose tranexamic acid. Double-blind, randomized clinical trial.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:3

    Topics: Analysis of Variance; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Cardiopulmon

1995
Intraoperative antifibrinolysis and blood-saving techniques in cardiac surgery. Prospective trial of 3 antifibrinolytic drugs.
    Texas Heart Institute journal, 1995, Volume: 22, Issue:3

    Topics: Adult; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Tests; Blood L

1995
[Use of tranexamic acid for bleeding control in myocardial revascularization].
    Arquivos brasileiros de cardiologia, 1994, Volume: 63, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood Loss, Surgical; Extracorporeal Circulation; Female; Hemostasis

1994
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
Tranexamic acid (Cyklokapron) reduces perioperative blood loss associated with total knee arthroplasty.
    British journal of anaesthesia, 1995, Volume: 74, Issue:5

    Topics: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; Humans; Knee

1995
The dose-response relationship of tranexamic acid.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Adult; Aged; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures

1995
Tranexamic acid significantly reduces blood loss associated with coronary revascularization.
    The Annals of thoracic surgery, 1995, Volume: 59, Issue:3

    Topics: Aged; Blood Coagulation Disorders; Blood Loss, Surgical; Cardiopulmonary Bypass; Erythrocyte Transfu

1995
Tranexamic acid as a mouthwash in anticoagulant-treated patients undergoing oral surgery. An alternative method to discontinuing anticoagulant therapy.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 75, Issue:1

    Topics: Anticoagulants; Blood Loss, Surgical; Dental Care for Disabled; Double-Blind Method; Female; Heart V

1993
The effect of preoperative tranexamic acid on blood loss after cardiac operations in children.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 111, Issue:5

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiopulmonary Bypass; Child; Child, Pre

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion after knee arthroplasty: a prospective, randomised, double-blind study of 86 patients.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Double-Blind Method; Female; Hemo

1996
Changes in coagulation patterns, blood loss and blood use after cardiopulmonary bypass: aprotinin vs tranexamic acid vs epsilon aminocaproic acid.
    The Journal of cardiovascular surgery, 1996, Volume: 37, Issue:4

    Topics: Aminocaproic Acid; Aprotinin; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Cardiopulm

1996
Tranexamic acid reduces blood loss, transfusion requirements, and coagulation factor use in primary orthotopic liver transplantation.
    Anesthesiology, 1996, Volume: 85, Issue:5

    Topics: Adult; Blood Coagulation Factors; Blood Loss, Surgical; Blood Transfusion; Humans; Liver Transplanta

1996
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Double-Blind Method; Female;

1997
Additional postbypass administration of tranexamic acid reduces blood loss after cardiac operations.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 113, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Volume; Cardiopulmonary Bypass; Female; H

1997
Surgical repair of congenital diaphragmatic hernia during extracorporeal membrane oxygenation: hemorrhagic complications and the effect of tranexamic acid.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Extracorporeal Membrane Oxygenatio

1997
The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgica

1997
Tranexamic acid reduces blood loss and transfusion in reoperative cardiac surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:9

    Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Blood Volume; C

1997
Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: a double-blind, randomized, placebo-controlled trial.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion; Coronary

1997
Beneficial effect of both tranexamic acid and aprotinin on blood loss reduction in reoperative valve replacement surgery.
    Circulation, 1997, Nov-04, Volume: 96, Issue:9 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Aprotinin; Blood Loss, Surgical; Double-Blind Method; Female; Heart

1997
Prophylactic tranexamic acid and epsilon-aminocaproic acid for primary myocardial revascularization.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:2

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Coronary Artery

1998
The effectiveness of low dose tranexamic acid in primary cardiac surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Analysis of Variance; Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Blood Transf

1998
[Comparative effect of tranexamic acid on the reduction of bleeding during and after cardiac surgery].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:7

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmo

1998
[The effect of intraoperative high-dose tranexamic acid on blood loss after operation for acute aortic dissection].
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1998, Volume: 46, Issue:7

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Aortic Aneurysm, Thoracic; A

1998
Fibrinolysis-adjusted perioperative low-dose aprotinin reduces blood loss in bypass operations.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Tests; Blood Loss, Surgical; Coronary Ar

1998
The effect of three different doses of tranexamic acid on blood loss after cardiac surgery with mild systemic hypothermia (32 degrees C).
    Journal of cardiothoracic and vascular anesthesia, 1998, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgic

1998
A comparative study of the postoperative allogeneic blood-sparing effect of tranexamic acid versus acute normovolemic hemodilution after total knee replacement.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Volume;

1999
Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgery.
    The Annals of thoracic surgery, 1999, Volume: 68, Issue:6

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Card

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Coagulation

1999
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Topical use of tranexamic acid in coronary artery bypass operations: a double-blind, prospective, randomized, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:3

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Doub

2000
Comparison of blood-conservation strategies in cardiac surgery patients at high risk for bleeding.
    Anesthesiology, 2000, Volume: 92, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Aprotinin; Blood Cell Count; Blood Loss, Su

2000
A retrospective survey of fibrinolysis as an indicator of poor outcome after cardiopulmonary bypass and a possible early sign of systemic inflammation syndrome.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiopulmonary Bypass; Female; Fibrinolysis; H

2000
Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Adult; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Coagulation; Blood Component Transfus

2000
Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: effects on perioperative bleeding and allogeneic transfusions.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 120, Issue:3

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Proced

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Reduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
    Archives of orthopaedic and trauma surgery, 2000, Volume: 120, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid reduces blood loss in total hip replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Coagulation; Blood Loss, Surgic

2000
Tranexamic acid in aortic valve replacement.
    Journal of cardiothoracic and vascular anesthesia, 2001, Volume: 15, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Aortic Valve; Blood Cell Count; Blood Loss, Surgical; Blood Transfusi

2001
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio

2001
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio

2001
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio

2001
A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio

2001
Effect of tranexamic acid on blood loss reduction after cardiopulmonary bypass.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2001, Volume: 49, Issue:5

    Topics: Aged; alpha-2-Antiplasmin; Analysis of Variance; Antifibrinolytic Agents; Antithrombin III; Blood Lo

2001
A comparative study of the postoperative allogeneic blood-sparing effects of tranexamic acid and of desmopressin after total knee replacement.
    Transfusion, 2001, Volume: 41, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2001
Relationship between factor VII activity and clinical efficacy of recombinant factor VIIa given by continuous infusion to patients with factor VIII inhibitors.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:4

    Topics: Adult; Antigens; Blood Loss, Surgical; Child; Child, Preschool; Drug Administration Schedule; Electi

2001
Does tranexamic acid reduce desmopressin-induced hyperfibrinolysis?
    The Journal of thoracic and cardiovascular surgery, 2002, Volume: 123, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Coro

2002
Hemostatic effects of tranexamic acid in elective thoracic aortic surgery: a prospective, randomized, double-blind, placebo-controlled study.
    The Journal of thoracic and cardiovascular surgery, 2002, Volume: 123, Issue:6

    Topics: Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Loss, Surgical; Double-Blind Method; Elect

2002
The effect of warm heart surgery on postoperative bleeding.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 103, Issue:6

    Topics: Aminocaproic Acid; Analysis of Variance; Blood Loss, Surgical; Blood Transfusion; Chi-Square Distrib

1992

Other Studies

649 other studies available for tranexamic acid and Blood Loss, Surgical

ArticleYear
Natural course of hemoglobin level after total knee arthroplasty and the benefit of tranexamic acid injection in the joint.
    Medicine, 2021, Sep-03, Volume: 100, Issue:35

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Hemoglobins; Humans; Injections

2021
[Effectiveness and safety of tranexamic acid combined with intraoperative controlled hypotension on reducing perioperative blood loss in primary total hip arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, Sep-15, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Hypotension,

2021
Tranexamic acid after cardiopulmonary bypass does not increase risk of postoperative seizures: a retrospective study.
    General thoracic and cardiovascular surgery, 2022, Volume: 70, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiopulmonary Bypass; Humans; Retrospective

2022
Tranexamic Acid in Patients With Cancer Undergoing Endoprosthetic Reconstruction: A Cost Analysis.
    The Journal of the American Academy of Orthopaedic Surgeons, 2021, Nov-15, Volume: 29, Issue:22

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Bone Neoplasms; Hospi

2021
[Application of tranexamic acid within the field of dentistry].
    Swiss dental journal, 2021, Oct-11, Volume: 131, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Dentistry; Humans; Tranexamic Acid

2021
Tranexamic acid use is associated with reduced intraoperative blood loss during spine surgery for Marfan syndrome.
    Spine deformity, 2022, Volume: 10, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Marfan Syndrome; Scoliosis; Tranexamic Acid

2022
Blood Loss Prophylaxis: Tranexamic Acid Is Safe Even in High-Risk Patients: Commentary on an article by Steven B. Porter, MD, et al.: ''Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Hip Fracture Undergoing Arth
    The Journal of bone and joint surgery. American volume, 2021, 10-20, Volume: 103, Issue:20

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2021
Comment on article by Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum

2022
Comment on Shodipo et al.: comparison of single versus double tranexamic acid dose regimens in reducing post-operative blood loss following intramedullary nailing of femoral fracture nonunions.
    International orthopaedics, 2022, Volume: 46, Issue:1

    Topics: Blood Loss, Surgical; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Ununited; Hum

2022
Dose tranexamic acid reduce blood loss associated with simultaneous bilateral distal tibial tubercle-high tibial osteotomy?
    BMC musculoskeletal disorders, 2021, Nov-10, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Hu

2021
The Efficiency of Simultaneous Systemic and Topical Use of Tranexamic Acid in Spinal Fusion Surgery.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2022, Volume: 83, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Hemorrhage; Spinal Fusio

2022
Efficacy of Tranexamic Acid on Blood Loss in Thoracolumbar Spinal Fusion Surgery.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:12

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cross-Sectional Studies; Humans; Lumbar Verteb

2021
Tranexamic acid use in simultaneous bilateral total knee arthroplasty : a comparison of intravenous and intra-articular applications, which is more effective?
    Acta orthopaedica Belgica, 2021, Volume: 87, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
Application of an adjusted patient blood management protocol in patients undergoing elective total hip arthroplasty: towards a zero-percent transfusion rate in renal patients-results from an observational cohort study.
    Journal of orthopaedic surgery and research, 2021, Nov-27, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2021
Simultaneous Bilateral Total Hip Arthroplasty With Contemporary Blood Management is Associated With a Low Risk of Allogeneic Blood Transfusion.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Fe

2022
Blood conservation outcomes and safety of tranexamic acid in coronary artery bypass graft surgery.
    International journal of cardiology, 2022, 02-01, Volume: 348

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Humans; Re

2022
Blood Management Following Total Joint Arthroplasty in an Aging Population: Can We Do Better?
    The Journal of arthroplasty, 2022, Volume: 37, Issue:4

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Aging; Antifibrinolytic Agents; Arthroplasty,

2022
Letter to the Editor Regarding "Cytotoxicity and Effect of Topical Application of Tranexamic Acid on Human Fibroblast in Spine Surgery".
    World neurosurgery, 2022, Volume: 157

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fibroblasts; Humans; Tranexamic Acid

2022
In Reply to the Letter to the Editor Regarding "Cytotoxicity and Effect of Topical Application of Tranexamic Acid on Human Fibroblast in Spine Surgery".
    World neurosurgery, 2022, Volume: 157

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fibroblasts; Humans; Tranexamic Acid

2022
Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty.
    Journal of orthopaedic surgery and research, 2021, Dec-20, Volume: 16, Issue:1

    Topics: Adenosine; Administration, Intravenous; Animals; Antifibrinolytic Agents; Arthroplasty, Replacement,

2021
Importance of tranexamic acid in pediatric monosutural craniosynostosis surgery.
    Journal of neurosurgery. Pediatrics, 2022, 04-01, Volume: 29, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; Infant; Retrospectiv

2022
Circulation collapse caused by intracardiac thrombosis associated with tranexamic acid administration: A case report.
    Medicine, 2021, Nov-24, Volume: 100, Issue:47

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Circulation; Blood Loss, Surgical; C

2021
Hip resurfacing and posterior approach total hip arthroplasty have equivalent blood loss when tranexamic acid is used: a propensity score matched cohort analysis.
    Archives of orthopaedic and trauma surgery, 2022, Volume: 142, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemoglobins; Humans;

2022
Tranexamic acid use decreases transfusion rate in children with cerebral palsy undergoing proximal femoral varus derotational osteotomy.
    Medicine, 2022, Jan-14, Volume: 101, Issue:2

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cerebral Palsy; Child;

2022
Efficacy of Tranexamic Acid in Reducing Seroma and Hematoma Formation Following Reduction Mammaplasty.
    Aesthetic surgery journal, 2022, 05-18, Volume: 42, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hematoma; Humans

2022
The effect of prophylactic use of tranexamic acid for cesarean section.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Hemoglobins; Humans; Infant

2022
Not all patients benefit from the postoperative antifibrinolytic treatment: clinical evidence against the universal use of tranexamic acid following total knee arthroplasty.
    Journal of orthopaedic surgery and research, 2022, Jan-29, Volume: 17, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2022
Clinical outcomes of tranexamic acid in acute hip hemiarthroplasties in frail geriatric patients.
    Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Frail Elderly;

2022
Local tranexamic acid reduces surgical blood loss.
    Wounds : a compendium of clinical research and practice, 2022, Volume: 33, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2022
Acute normovolemic hemodilution in combination with tranexamic acid is an effective strategy for blood management in lumbar spinal fusion surgery.
    Journal of orthopaedic surgery and research, 2022, Feb-05, Volume: 17, Issue:1

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemodilution; Humans; Intraopera

2022
Editorial Commentary: The Current Evidence in Support of Tranexamic Acid in Arthroscopic Surgery Is Poor.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2022, Volume: 38, Issue:2

    Topics: Antifibrinolytic Agents; Arthroscopy; Blood Loss, Surgical; Humans; Pulmonary Embolism; Tranexamic A

2022
Hypotensive Anesthesia Combined with Tranexamic Acid Reduces Perioperative Blood Loss in Simultaneous Bilateral Total Hip Arthroplasty: A Retrospective Cohort Study.
    Orthopaedic surgery, 2022, Volume: 14, Issue:3

    Topics: Adult; Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Sur

2022
Artificial neural networks for the prediction of transfusion rates in primary total hip arthroplasty.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:3

    Topics: Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Humans; Neural Networks, Co

2023
Tranexamic acid improves early postoperative mobilization in cancer patients undergoing endoprosthetic reconstruction.
    Journal of surgical oncology, 2022, Volume: 125, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Bone Neoplasms; Humans; Postoperative Hemorrhage; Ret

2022
Avoiding Femoral Canal Instrumentation in Computer-Assisted Total Knee Arthroplasty With Contemporary Blood Management Had Minimal Differences in Blood Loss and Transfusion Rates Compared to Conventional Techniques.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:7

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Humans; Retro

2022
Variable Response to Antifibrinolytics Correlates with Blood-loss and Transfusion in Posterior Spinal Fusion.
    Spine deformity, 2022, Volume: 10, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Fibrinolysin; Humans; Prospective Studies; Spinal Fus

2022
Tranexamic acid reduces blood loss in primary total hip arthroplasty performed using the direct anterior approach: a one-center retrospective observational study.
    Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2022, Mar-07, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Retrospective

2022
[Standard administration of tranexamic acid for prophylaxis in endoprosthetics: a good idea?]
    Der Orthopade, 2022, Volume: 51, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Plastic Surgery Procedures; Tranexamic Acid

2022
Post-operative tranexamic acid decreases chest tube drainage following vertebral body tethering surgery for scoliosis correction.
    Spine deformity, 2022, Volume: 10, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Chest Tubes; Drainage; Humans; Scoliosis;

2022
No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA.
    Clinical orthopaedics and related research, 2022, 04-01, Volume: 480, Issue:4

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2022
Perioperative administration of tranexamic acid in hip fracture surgery (The PATHS study): national audit of current practice.
    Annals of the Royal College of Surgeons of England, 2023, Volume: 105, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Femoral Neck Fracture

2023
Tranexamic acid protects against implant-associated infection by reducing biofilm formation.
    Scientific reports, 2022, 03-22, Volume: 12, Issue:1

    Topics: Animals; Antifibrinolytic Agents; Biofilms; Blood Loss, Surgical; Humans; Mice; Postoperative Compli

2022
Tranexamic acid reduced blood transfusions in acute burn surgery: A retrospective case-controlled trial.
    Burns : journal of the International Society for Burn Injuries, 2022, Volume: 48, Issue:3

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Burns; Case-Control S

2022
Local Infiltration of Tranexamic Acid During Facelift Improves Operating Room Efficiency: A Matched Patient Study.
    Aesthetic surgery journal, 2022, 08-24, Volume: 42, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Case-Control Studies; Humans; Oper

2022
The effect of tranexamic acid on hidden blood loss in total hip arthroplasty.
    Joint diseases and related surgery, 2022, Volume: 33, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2022
Closed suction drainage is not beneficial in hybrid total hip arthroplasty with intra-articular administration of tranexamic acid: a propensity score-matched cohort study.
    International orthopaedics, 2022, Volume: 46, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Cohort Studies; Human

2022
Efficacy and safety of intravenous combined with topical administration of tranexamic acid in reducing blood loss in opening wedge high tibial osteotomy procedure: A retrospective case-control study.
    Acta orthopaedica et traumatologica turcica, 2022, Volume: 56, Issue:2

    Topics: Activities of Daily Living; Administration, Intravenous; Administration, Topical; Antifibrinolytic A

2022
Tranexamic acid reduces perioperative bleeding.
    Nature reviews. Cardiology, 2022, Volume: 19, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Comparison of weight-based versus standard dosing of tranexamic acid for blood loss and transfusion amount in knee arthroplasty without tourniquet.
    Acta orthopaedica Belgica, 2022, Volume: 88, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Hemoglobins;

2022
Efficacy and safety of tranexamic acid in patients undergoing surgery for bone and soft tissue tumors: a propensity score matching analysis.
    Japanese journal of clinical oncology, 2022, Sep-18, Volume: 52, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Propensity Score; Retrospe

2022
Blood Transfusion can be Avoided in Single-Anesthetic Bilateral Total Knee Arthroplasty.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:10

    Topics: Anesthetics; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood T

2022
Safety and efficacy of intravenous or topical tranexamic acid administration in surgery: a protocol for a systematic review and network meta-analysis.
    BMJ open, 2022, 05-09, Volume: 12, Issue:5

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical;

2022
Cytotoxicity of tranexamic acid to tendon and bone in vitro: Is there a safe dosage?
    Journal of orthopaedic surgery and research, 2022, May-15, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Injections, Intra-Articular; Tendons; Tranexa

2022
Impact of gender differences on hemostasis in patients after coronary artery bypass grafts surgeries in the context of tranexamic acid administration.
    Journal of cardiothoracic surgery, 2022, May-21, Volume: 17, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Coronary Artery Bypass; Female; Hemostasis; Humans; M

2022
Clinical Application Effects of Different Preoperative Blood Management Schemes in Older Patients with Delayed Intertrochanteric Fracture Surgery.
    Clinical interventions in aging, 2022, Volume: 17

    Topics: Aged; Blood Loss, Surgical; Erythropoietin; Hip Fractures; Humans; Iron; Retrospective Studies; Tran

2022
The efficacy and safety of intravenous tranexamic acid on blood loss during total ankle replacement: a retrospective study.
    Scientific reports, 2022, 06-09, Volume: 12, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Ankle; Blood Loss,

2022
Hidden blood loss of total knee arthroplasty in hemophilia arthritis: an analysis of influencing factors.
    BMC musculoskeletal disorders, 2022, Jun-17, Volume: 23, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blo

2022
Evaluation of the safety of tranexamic acid use in pediatric patients undergoing spinal fusion surgery: a retrospective comparative cohort study.
    BMC musculoskeletal disorders, 2022, Jul-08, Volume: 23, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Cohort Studies; Humans; Pulmonary

2022
Comparison of blood loss between tranexamic acid-soaked absorbable Gelfoam and topical retrograde injection via drainage catheter plus clamping in cervical laminoplasty surgery.
    BMC musculoskeletal disorders, 2022, Jul-14, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Catheters; Constriction; Drainage; Gelatin Sponge, Ab

2022
The Effect of Tranexamic Acid on Operative and Postoperative Blood Loss in Transforaminal Lumbar Interbody Fusions.
    World neurosurgery, 2022, Volume: 166

    Topics: Adult; Blood Loss, Surgical; Child; Humans; Lumbar Vertebrae; Postoperative Hemorrhage; Retrospectiv

2022
Bleeding and Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Does tranexamic acid reliably reduce blood loss in proximal femur fracture surgery?
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:1

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Co

2023
Comparison of trauma-dosed tranexamic acid versus aminocaproic acid in cardiac surgery in the setting of drug shortage.
    Journal of cardiac surgery, 2022, Volume: 37, Issue:10

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Human

2022
The effectiveness of a multifaceted, group-facilitated audit and feedback intervention to increase tranexamic acid use during total joint arthroplasty.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022, Volume: 69, Issue:9

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2022
Combination effect of intraoperative and postoperative intravenous tranexamic acid in hip hemiarthroplasty. A propensity score matched analysis.
    Injury, 2022, Volume: 53, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiarthroplasty; Hum

2022
Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group.
    Paediatric anaesthesia, 2022, Volume: 32, Issue:12

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; I

2022
Fertility-sparing surgery for diffuse adenomyosis: a narrated, stepwise approach to the Osada procedure.
    Fertility and sterility, 2022, Volume: 118, Issue:3

    Topics: Adenomyoma; Adenomyosis; Adult; Blood Loss, Surgical; Contraceptive Agents; Female; Hemostatics; Hum

2022
[Effects of oral and intravenous tranexamic acid on perioperative blood loss after lumbar spinal canal decompression and fusion].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2022, Aug-25, Volume: 35, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Decompression; Humans; Postoperative Hemorrhage; Spin

2022
Reducing transfusion in hip arthroplasty: tranexemic acid diminishes influence of anesthesia administered.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:6

    Topics: Anesthesia, General; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical;

2023
Tranexamic acid for cesarean delivery: evidence of fibrinolysis?
    American journal of obstetrics and gynecology, 2023, Volume: 228, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Fibrinolysis; Humans; Pregn

2023
Tranexamic Acid and Prothrombotic Complications Following Total Hip and Total Knee Arthroplasty: A Population-Wide Safety Analysis Accounting for Surgeon Selection Bias.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2023
How does tranexamic acid affect blood transfusion and bleeding amount in pelvis-acetabulum fractures treated with open reduction and internal fixation?
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:9

    Topics: Acetabulum; Blood Loss, Surgical; Blood Transfusion; Fracture Fixation, Internal; Fractures, Bone; H

2022
Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
    The New England journal of medicine, 2022, 09-01, Volume: 387, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
    The New England journal of medicine, 2022, 09-01, Volume: 387, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Tranexamic Acid in Patients Undergoing Noncardiac Surgery. Reply.
    The New England journal of medicine, 2022, 09-01, Volume: 387, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Tranexamic acid for safer surgery: the time is now.
    The British journal of surgery, 2022, 11-22, Volume: 109, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Re: Tranexamic Acid in Patients Undergoing Noncardiac Surgery.
    European urology, 2022, Volume: 82, Issue:6

    Topics: Blood Loss, Surgical; Blood Transfusion; Humans; Tranexamic Acid

2022
Effect of Topical Administration of Tranexamic Acid on Intraoperative and Postoperative Blood Loss during Posterior Cervical Laminectomy and Fusion Surgery: A Retrospective Study.
    Turkish neurosurgery, 2023, Volume: 33, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemostatics; Humans;

2023
Tranexamic acid for safer surgery: the time is now.
    British journal of anaesthesia, 2022, Volume: 129, Issue:4

    Topics: Blood Loss, Surgical; Clinical Trials as Topic; Humans; Tranexamic Acid

2022
Effectiveness of prophylactic tranexamic acid versus placebo or no intervention for reducing blood loss in healthy patients undergoing orthognathic surgery: a systematic review protocol.
    JBI evidence synthesis, 2023, 02-01, Volume: 21, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemoglobins; Humans; Meta-Analysis as Topic; Orthogna

2023
Effect of early continuously intravenous tranexamic acid on perioperative blood loss in thoracolumbar burst fractures with neurological symptoms.
    Medicine, 2022, Sep-09, Volume: 101, Issue:36

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Retrospective St

2022
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2022, Volume: 54, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Female; Humans; Male; Mastectomy; M

2022
Predictors and complications of blood transfusion in rheumatoid arthritis patients undergoing total joint arthroplasty.
    Clinical rheumatology, 2023, Volume: 42, Issue:1

    Topics: Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Hip; Blood Loss, Surgical

2023
Optimal Release Timing of Drain Clamping to Reduce Postoperative Bleeding after Total Knee Arthroplasty with Intraarticular Injection of Tranexamic Acid.
    Medicina (Kaunas, Lithuania), 2022, Sep-05, Volume: 58, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Constriction; Draina

2022
Comment on: Tranexamic acid for safer surgery: the time is now.
    The British journal of surgery, 2022, 11-22, Volume: 109, Issue:12

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Tranexamic Acid and Intraoperative and Postoperative Accumulative Bleeding in Elective Degenerative Spine Surgery.
    Yonsei medical journal, 2022, Volume: 63, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Elective Surgical Procedures; Huma

2022
On Patient Safety: Concerns About Topical Tranexamic Acid in Spine Surgery.
    Clinical orthopaedics and related research, 2022, 11-01, Volume: 480, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2022
Does the clamping method in local and systemic TXA applications in total knee arthroplasty change the game?: A retrospective comparative cohort study.
    Medicine, 2022, Sep-23, Volume: 101, Issue:38

    Topics: Adult; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Cohort Studie

2022
Tranexamic acid is not associated with decreased infection risk after primary shoulder arthroplasty: a cohort study of 9276 patients.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Cohort Stu

2023
Effects of tranexamic acid on vascular occlusive events and perioperative resuscitation in patients with atrial fibrillation undergoing total joint arthroplasty.
    Chinese medical journal, 2022, 10-05, Volume: 135, Issue:19

    Topics: Antifibrinolytic Agents; Arthroplasty; Arthroplasty, Replacement, Hip; Atrial Fibrillation; Blood Lo

2022
Does living at high altitude increase the risk of bleeding events after total knee arthroplasty? A retrospective cohort study.
    International orthopaedics, 2023, Volume: 47, Issue:1

    Topics: Altitude; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fibrin Fib

2023
Tranexamic acid in pertrochanteric fractures: a retrospective analysis of perioperative outcomes after fixation with a proximal femoral nail.
    BMC musculoskeletal disorders, 2022, Nov-03, Volume: 23, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femoral Fractures; Humans; Postoperative Hemorrhage;

2022
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
The safety of tranexamic acid administration in total knee arthroplasty: a population-based study from Taiwan.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2022, Nov-19, Volume: 23, Issue:1

    Topics: Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2022
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Comment on Br J Anaesth 2022; 129: 459-61.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2023
Intravenous Tranexamic Acid Reduces Blood Loss in Multilevel Spine Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2023, Feb-15, Volume: 31, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Vertebrae

2023
Intravenous Tranexamic Acid Reduces Blood Loss in Multilevel Spine Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2023, Feb-15, Volume: 31, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Vertebrae

2023
Intravenous Tranexamic Acid Reduces Blood Loss in Multilevel Spine Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2023, Feb-15, Volume: 31, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Vertebrae

2023
Intravenous Tranexamic Acid Reduces Blood Loss in Multilevel Spine Surgeries.
    The Journal of the American Academy of Orthopaedic Surgeons, 2023, Feb-15, Volume: 31, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Vertebrae

2023
Is Tranexamic Acid Effective for Hemostasis During Endoscopic Sinus Surgery?
    The Laryngoscope, 2023, Volume: 133, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Hemostasis; Hemostasis, Surgical; Humans;

2023
Is Tranexamic Acid Effective for Hemostasis During Endoscopic Sinus Surgery?
    The Laryngoscope, 2023, Volume: 133, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Hemostasis; Hemostasis, Surgical; Humans;

2023
Is Tranexamic Acid Effective for Hemostasis During Endoscopic Sinus Surgery?
    The Laryngoscope, 2023, Volume: 133, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Hemostasis; Hemostasis, Surgical; Humans;

2023
Is Tranexamic Acid Effective for Hemostasis During Endoscopic Sinus Surgery?
    The Laryngoscope, 2023, Volume: 133, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Endoscopy; Hemostasis; Hemostasis, Surgical; Humans;

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
Tranexamic acid for safer surgery: does the evidence support preventative use? Response to Br J Anaesth 2023; 130: e23-e24.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Gastrointestinal Hemorrhage; Humans; Tranexamic Acid

2023
The Effect of Systemic Tranexamic Acid on Blood Loss and Blood Transfusion Requirement in Elective Total Hip Arthroplasty.
    Ortopedia, traumatologia, rehabilitacja, 2022, Oct-31, Volume: 24, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2022
The Effect of Systemic Tranexamic Acid on Blood Loss and Blood Transfusion Requirement in Elective Total Hip Arthroplasty.
    Ortopedia, traumatologia, rehabilitacja, 2022, Oct-31, Volume: 24, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2022
The Effect of Systemic Tranexamic Acid on Blood Loss and Blood Transfusion Requirement in Elective Total Hip Arthroplasty.
    Ortopedia, traumatologia, rehabilitacja, 2022, Oct-31, Volume: 24, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2022
The Effect of Systemic Tranexamic Acid on Blood Loss and Blood Transfusion Requirement in Elective Total Hip Arthroplasty.
    Ortopedia, traumatologia, rehabilitacja, 2022, Oct-31, Volume: 24, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2022
Topical Tranexamic Acid Can Be Used Safely Even in High Risk Patients: Deep Vein Thrombosis Examination Using Routine Ultrasonography of 510 Patients.
    Medicina (Kaunas, Lithuania), 2022, Nov-29, Volume: 58, Issue:12

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Retrospective St

2022
Combination of Intravenous and Intra-Articular Application of Tranexamic Acid and Epsilon-Aminocaproic Acid in Primary Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.
    Orthopaedic surgery, 2023, Volume: 15, Issue:3

    Topics: Administration, Intravenous; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement,

2023
Effect of administration of tranexamic acid on blood loss and transfusion requirements in children undergoing posterior fossa tumor excision: a retrospective cohort study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023, Volume: 39, Issue:4

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Brain Neoplasms; Child

2023
High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery-Reply.
    JAMA, 2023, 01-03, Volume: 329, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Erythrocyte Transfusion;

2023
High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery.
    JAMA, 2023, 01-03, Volume: 329, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Erythrocyte Transfusion;

2023
Predisposing factors for allogeneic blood transfusion in patients with ankylosing spondylitis undergoing primary unilateral total hip arthroplasty: a retrospective study.
    Journal of orthopaedic surgery and research, 2023, Jan-04, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; He

2023
Tranexamic acid in total knee arthroplasty.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2023
Predicting Postoperative Anemia and Blood Transfusion Following Total Knee Arthroplasty.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:7

    Topics: Aged; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood

2023
The Administration of Tranexamic Acid For Complex Spine Surgery.
    AANA journal, 2023, Volume: 91, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Perioperative Pe

2023
Intravenous Tranexamic Acid Given at Femoral Fragility Fracture Surgery Reduces Blood Transfusion Requirements Fourfold.
    World journal of surgery, 2023, Volume: 47, Issue:4

    Topics: Administration, Intravenous; Aged, 80 and over; Anticoagulants; Blood Loss, Surgical; Blood Transfus

2023
The Usage of Intravenous Tranexamic Acid in Reduction Mammaplasty Safely Reduces Hematoma Rates.
    Annals of plastic surgery, 2023, 06-01, Volume: 90, Issue:6S Suppl 4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hematoma; Humans; Mammaplasty; Retrospective

2023
Preliminary outcome of use of parenterally administered tranexamic acid during primary total knee replacement.
    Nigerian journal of clinical practice, 2023, Volume: 26, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Topical tranexamic acid in intramedullary nailing for the treatment of intertrochanteric fractures in the elderly: A protocol for systematic review and meta-analysis.
    Medicine, 2023, Feb-10, Volume: 102, Issue:6

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Sur

2023
Characteristics and Outcomes of Liver Transplantation Recipients after Tranexamic Acid Treatment and Platelet Transfusion: A Retrospective Single-Centre Experience.
    Medicina (Kaunas, Lithuania), 2023, Jan-23, Volume: 59, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cohort Studies; Humans; Liver Transplantation; Platel

2023
Local Infiltration of Tranexamic Acid in Breast Reduction for Symptomatic Macromastia.
    Annals of plastic surgery, 2023, 06-01, Volume: 90, Issue:6S Suppl 4

    Topics: Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Mammaplasty; Tranexamic Ac

2023
Cost Analysis of Aprotinin Reintroduction in French Cardiac Surgery Centres: A Real-World Data-Based Analysis.
    Advances in therapy, 2023, Volume: 40, Issue:4

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Costs and Cos

2023
The efficacy of aggressive warming combined with tranexamic acid during total hip arthroplasty: a single-center retrospective study from southern China.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:4

    Topics: Arthroplasty, Replacement, Hip; Blood Loss, Surgical; China; Humans; Retrospective Studies; Tranexam

2023
The cost effectiveness of tranexamic acid for preventing periprosthetic joint infection following total shoulder arthroplasty: a break-even analysis.
    Journal of shoulder and elbow surgery, 2023, Volume: 32, Issue:6

    Topics: Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement, Hip; Arthroplasty, Replac

2023
Topical administration of tranexamic acid reduces postoperative blood loss and inflammatory response in knee arthroscopic arthrolysis: a retrospective comparative study.
    BMC musculoskeletal disorders, 2023, Apr-05, Volume: 24, Issue:1

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroscopy; Blood Loss, Surgical; Hemarthrosis; H

2023
Tranexamic acid as a novel adjunct in the management of vessel perforation complicating Endovascular Clot Retrieval.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2023, Volume: 32, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Hemorrhage; Humans; Retrospecti

2023
Epsilon aminocaproic acid is associated with acute kidney injury after life-threatening hemorrhage in children.
    Transfusion, 2023, Volume: 63 Suppl 3

    Topics: Acute Kidney Injury; Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; C

2023
The efficacy and safety of tranexamic acid in rheumatoid arthritis patients undergoing simultaneous bilateral total knee arthroplasty: a multicenter retrospective study.
    BMC musculoskeletal disorders, 2023, May-15, Volume: 24, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Replaceme

2023
Antifibrinolytic agents and seizure risk in neonates undergoing cardiac surgery.
    Paediatric anaesthesia, 2023, Volume: 33, Issue:9

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Human

2023
Does the Use of Tranexamic Acid in Patients Who Have Preoperative Coagulopathy Undergoing Total Joint Arthroplasty Normalize Their Risk of Complications? A Matched Equivalence Analysis.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:11

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2023
Use of Subcutaneous Injection of Epinephrine and Triamcinolone with Tranexamic Acid Reduces Blood Loss, Transfusion Rates, and Length of Stay in Open Sagittal Craniosynostosis Repair.
    The Journal of craniofacial surgery, 2023, Oct-01, Volume: 34, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Bupivacaine; Craniosynostoses; Hemoglobins; Humans; I

2023
Wound Healing Complications With Tranexamic Acid: Not the Silver Bullet After All.
    Aesthetic surgery journal, 2023, 11-16, Volume: 43, Issue:12

    Topics: Administration, Topical; Anesthetics, Local; Antifibrinolytic Agents; Blood Loss, Surgical; Humans;

2023
Topical tranexamic acid reduces postoperative hematomas in reduction mammaplasties.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2023, Volume: 83

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Breast Neoplasms; Cohort Stu

2023
The efficacy and safety of intravenous administration of tranexamic acid in patients undergoing cardiac surgery: Evidence from a single cardiovascular center.
    Medicine, 2023, May-19, Volume: 102, Issue:20

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical

2023
Die perioperative Gabe von Tranexamsäure.
    Zeitschrift fur Orthopadie und Unfallchirurgie, 2023, Volume: 161, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Tranexamic Acid

2023
Efficacy and safety of using aminocaproic acid and tranexamic acid during the perioperative period for treating trochanteric fractures in elderly femurs.
    BMC musculoskeletal disorders, 2023, Jul-03, Volume: 24, Issue:1

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Posto

2023
Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection.
    Journal of surgical oncology, 2023, Volume: 128, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Postoperative Complications; Pulmonary Emboli

2023
FIT for surgery: fractures, iron, and tranexamic acid.
    The Lancet. Haematology, 2023, Volume: 10, Issue:9

    Topics: Blood Loss, Surgical; Blood Transfusion; Humans; Iron; Tranexamic Acid

2023
A prophylactic TXA administration effectively reduces the risk of intraoperative bleeding during open management of pelvic and acetabular fractures.
    Scientific reports, 2023, 08-02, Volume: 13, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip F

2023
Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study.
    International orthopaedics, 2023, Volume: 47, Issue:12

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2023
Risk factors for blood transfusion and postoperative anaemia following total knee arthroplasty.
    The bone & joint journal, 2023, Oct-01, Volume: 105-B, Issue:10

    Topics: Aged; Anemia; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Female; Hemo

2023
Examining the safety profile of a standard dose tranexamic acid regimen in spine surgery.
    Neurosurgical focus, 2023, Volume: 55, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Retrospective Studies; Spine; Thromboe

2023
Efficacy of tranexamic acid supplemented with local infiltration analgesia in reducing blood loss in patients undergoing unicompartmental knee arthroplasty.
    Scientific reports, 2023, 10-12, Volume: 13, Issue:1

    Topics: Analgesia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; M

2023
Thromboembolic Complications Following Perioperative Tranexamic Acid Administration.
    The Journal of surgical research, 2024, Volume: 293

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Retrospective Studies; Tranexamic

2024
Is topical tranexamic acid combined with endoscopic hemostasis superior to endoscopic hemostasis alone?
    Gastrointestinal endoscopy, 2023, Volume: 98, Issue:6

    Topics: Administration, Topical; Blood Loss, Surgical; Hemostasis, Endoscopic; Humans; Tranexamic Acid

2023
Postoperative clinical outcomes with and without short-term intravenous tranexamic acid after posterior lumbar interbody fusion: A prospective cohort study.
    Medicine, 2023, Nov-17, Volume: 102, Issue:46

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Vertebrae

2023
An observational study of an adjusted patient blood management protocol intended to lower rates of transfusion following total knee arthroplasty in patients with preoperative anemia.
    Journal of orthopaedic surgery and research, 2023, Dec-02, Volume: 18, Issue:1

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transf

2023
A Decline in Overutilization of Transfusion after Total Knee Arthroplasty Using Pharmacological Agents for Patient Blood Management in South Korea: An Analysis Based on the Korean National Health Insurance Claims Database from 2008 to 2019.
    Clinics in orthopedic surgery, 2023, Volume: 15, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2023
Management of Spinal Emergencies in Patients on Direct Oral Anticoagulants.
    World neurosurgery, 2019, Volume: 131

    Topics: Acute Disease; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Blood Coagulation Factors; Bl

2019
The value of tranexamic acid for patients with preoperative anemia in primary total knee arthroplasty.
    European journal of medical research, 2019, Aug-12, Volume: 24, Issue:1

    Topics: Aged; Anemia; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Chi-Square Distribution; Female

2019
Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur.
    Medicine, 2019, Volume: 98, Issue:35

    Topics: Acupuncture Points; Acupuncture Therapy; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Los

2019
Greater Blood Loss in Contemporary Cementless Total Knee Arthroplasty than Cemented Total Knee Arthroplasty despite Tranexamic Acid Use: A Match-Controlled Retrospective Study.
    The journal of knee surgery, 2021, Volume: 34, Issue:4

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Bone Ce

2021
Tranexamic acid may benefit patients undergoing total hip/knee arthroplasty because of haemophilia.
    BMC musculoskeletal disorders, 2019, Sep-04, Volume: 20, Issue:1

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Arthralgia; Arthroplasty, Replacement,

2019
Single Low Dose of rFVIIa Combined with Antifibrinolytic Agent is a Simple and Safe Treatment for Factor XI-Deficient Patients undergoing Surgery.
    Thrombosis and haemostasis, 2019, Volume: 119, Issue:12

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Schedule; Factor VII

2019
Local Infiltration of Tranexamic Acid With Local Anesthetic Reduces Intraoperative Facelift Bleeding: A Preliminary Report.
    Aesthetic surgery journal, 2020, 05-16, Volume: 40, Issue:6

    Topics: Anesthetics, Local; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Middle Aged; Rhyt

2020
Comparison of the Effects of Intravenous and Oral Tranexamic Acid on Perioperative Hemoglobin Levels During Total Knee Arthroplasty.
    The Annals of pharmacotherapy, 2020, Volume: 54, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Aged; Antifibrinolytic Agents; Arthro

2020
Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice?
    Bulletin of the Hospital for Joint Disease (2013), 2018, Volume: 76, Issue:3

    Topics: Adolescent; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Cohort Studies;

2018
Tranexamic Acid Administration Is Not Associated With an Increase in Complications in High-Risk Patients Undergoing Primary Total Knee or Total Hip Arthroplasty: A Retrospective Case-Control Study of 38,220 Patients.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2020
Postoperative ultrasound evaluation for deep vein thrombosis after knee replacement surgery performed with tranexamic acid.
    Minerva anestesiologica, 2020, Volume: 86, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans

2020
Tranexamic acid in cardiac surgery: a systematic review and meta-analysis (protocol).
    BMJ open, 2019, 09-17, Volume: 9, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Meta-Analysis as

2019
Prothrombin Complex Concentrate before Urgent Surgery in Patients Treated with Rivaroxaban and Apixaban.
    Acta haematologica, 2020, Volume: 143, Issue:3

    Topics: Academic Medical Centers; Aged; Aged, 80 and over; Atrial Fibrillation; Blood Coagulation Factors; B

2020
The impact of patient blood management on blood utilization and clinical outcomes in complex spine surgery.
    Transfusion, 2019, Volume: 59, Issue:12

    Topics: Adult; Aged; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Logistic Models; Male; Middle

2019
[Research progress on tranexamic acid in traumatic orthopedic surgery].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019, Nov-15, Volume: 33, Issue:11

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; O

2019
Single dose Intravenous Tranexamic acid may not be adequate to reduce blood loss and blood transfusion requirement in patients undergoing single stage bilateral total knee arthroplasty.
    Acta orthopaedica Belgica, 2019, Volume: 85, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2019
The Dangers and Concerns of Intra-articular Tranexamic Acid.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2019, Volume: 35, Issue:11

    Topics: Anterior Cruciate Ligament Reconstruction; Blood Loss, Surgical; Hemarthrosis; Humans; Injections, I

2019
Tranexamic Acid Is Associated With Reduced Periprosthetic Joint Infection After Primary Total Joint Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2020
One Versus Two Doses of Intravenous Tranexamic Acid in Total Knee Arthroplasty.
    The journal of knee surgery, 2021, Volume: 34, Issue:7

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2021
Comparison of the Coagulation Profile of Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion With and Without Tranexamic Acid.
    Spine deformity, 2019, Volume: 7, Issue:6

    Topics: Adolescent; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusio

2019
What's New in Adult Reconstructive Knee Surgery.
    The Journal of bone and joint surgery. American volume, 2020, 01-15, Volume: 102, Issue:2

    Topics: Analgesics, Opioid; Anesthesia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2020
CORR Insights®: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
    Clinical orthopaedics and related research, 2020, Volume: 478, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Cytotoxicity and effect on wound re-epithelialization after topical administration of tranexamic acid.
    BJS open, 2019, Volume: 3, Issue:6

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Cell Culture Techniques; Cel

2019
Intravenous Tranexamic Acid for Reducing Perioperative Blood Loss During Revision Surgery for Vancouver Type B Periprosthetic Femoral Fractures After Total Hip Arthroplasty: A Retrospective Study.
    Orthopaedic surgery, 2020, Volume: 12, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2020
Tranexamic Acid Reduces Total Blood Loss and Inflammatory Response in Computer-Assisted Navigation Total Knee Arthroplasty.
    BioMed research international, 2019, Volume: 2019

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2019
Response to Letter to the Editor on "A Prospective Double-Blind Placebo Controlled Trial of Topical Tranexamic Acid in Total Knee Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Double-Blind Method;

2020
Simultaneous Bilateral Total Knee Arthroplasty Becomes Safer after Institution of Optimal Perioperative Management: A Longitudinal Cohort Study.
    The journal of knee surgery, 2021, Volume: 34, Issue:9

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Longitudinal Studies; Postoperative C

2021
Letter to the Editor on "A Prospective Double-Blind Placebo Controlled Trial of Topical Tranexamic Acid in Total Knee Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Double-Blind Method;

2020
Reply to the Letter to the Editor: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
    Clinical orthopaedics and related research, 2020, Volume: 478, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Tranexamic Acid Utilization in Craniosynostosis Surgery.
    Turkish neurosurgery, 2020, Volume: 30, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Craniosynostoses; Craniotomy; Female; Humans; Infant,

2020
Reply to the Letter to the Editor: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
    Clinical orthopaedics and related research, 2020, Volume: 478, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
The Use of Tranexamic Acid (TXA) in Neuromuscular Hip Reconstruction: Can We Alter the Need for Blood Transfusion?
    Journal of pediatric orthopedics, 2020, Volume: 40, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Ch

2020
Letter to the Editor: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
    Clinical orthopaedics and related research, 2020, Volume: 478, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Letter to the Editor: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
    Clinical orthopaedics and related research, 2020, Volume: 478, Issue:4

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:6S

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2020
Tranexamic acid in emergency care.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2020, Volume: 27, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Emergency Medical Services; Emergency Treatment; Huma

2020
The efficacy and safety of multiple-dose intravenous tranexamic acid in reducing perioperative blood loss in patients with thoracolumbar burst fracture.
    Clinical neurology and neurosurgery, 2020, Volume: 193

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion

2020
Administration of Tranexamic Acid Improves Long-Term Outcomes in Total Knee Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:6S

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Safety and efficacy of tranexamic acid in children with cerebral palsy undergoing femoral varus derotational osteotomy: a double cohort study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020, Volume: 30, Issue:6

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cerebral Palsy; Child;

2020
Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Epinephrine; Female; Fractur

2020
The effect of topical and systemic tranexamic acid on fracture healing in rats.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:2

    Topics: Administration, Topical; Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration

2020
Comment on the article "The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial".
    International orthopaedics, 2020, Volume: 44, Issue:6

    Topics: Anti-Inflammatory Agents; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surg

2020
[A comparative study of Taylor spatial frame and unilateral external fixator in treatment of tibiofibular open fractures].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Apr-15, Volume: 34, Issue:4

    Topics: Blood Loss, Surgical; External Fixators; Fracture Fixation, Internal; Fracture Healing; Fractures, O

2020
Perioperative anesthetic management in a patient with factor XI deficiency undergoing coronary artery bypass graft surgery.
    Journal of cardiac surgery, 2020, Volume: 35, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Blood Loss, Surgical; Cardiopulmonary Bypass; Coronary Artery Bypass;

2020
How treatment delay may lead to loss of effectiveness of tranexamic acid.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Time-to-Treatment; Tranexamic Acid; Treatment

2020
Venous thromboembolism after tranexamic acid administration: legitimate risk or statistical confounder?
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Tranexamic A

2020
Perspectives on tranexamic acid in surgery.
    ANZ journal of surgery, 2020, Volume: 90, Issue:4

    Topics: Antifibrinolytic Agents; Blood Coagulation; Blood Loss, Surgical; Hemorrhage; Humans; Publications;

2020
Tranexamic acid administration during total joint arthroplasty surgery is not associated with an increased risk of perioperative seizures: a national database analysis.
    Regional anesthesia and pain medicine, 2020, Volume: 45, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Seizures; Tra

2020
Tranexamic acid with a pre-operative suspension of anticoagulation decreases operative time and blood transfusion in the treatment of pelvic and acetabulum fractures.
    International orthopaedics, 2020, Volume: 44, Issue:9

    Topics: Acetabulum; Anticoagulants; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans

2020
A protocol of situation-dependent transfusion, erythropoietin and tranexamic acid reduces transfusion in fronto-orbital advancement for metopic and coronal craniosynostosis.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021, Volume: 37, Issue:1

    Topics: Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Erythropoietin; Humans; Infant; Retrospec

2021
Tranexamic Acid Does Not Reduce the Risk of Transfusion in Rheumatoid Arthritis Patients Undergoing Total Joint Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Hip; Arthroplasty, Replac

2020
In the Era of Tranexamic Acid, are Type and Screens for Primary Total Joint Arthroplasty Obsolete?
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2020
Effect of the application of the "Patient blood management" programme on the approach to elective hip and knee arthroplasties.
    Medicina clinica, 2020, 11-27, Volume: 155, Issue:10

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfu

2020
Postoperative Intravenous Iron Supplementation Does Not Improve Hemoglobin Level and Transfusion Rate Following Staged Bilateral Total Knee Arthroplasty.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Cohort Studies; Diet

2020
Peri-operative administration of tranexamic acid in lower limb arthroplasty: a multicentre, prospective cohort study.
    Anaesthesia, 2020, Volume: 75, Issue:8

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement; Arthroplasty, R

2020
Letter to the Editor on "In the Era of Tranexamic Acid, Are Type and Screens for Primary Total Joint Arthroplasty Obsolete?"
    The Journal of arthroplasty, 2020, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2020
Response to Letter to the Editor on "In the Era of Tranexamic Acid, Are Type and Screens for Primary Total Joint Arthroplasty Obsolete?"
    The Journal of arthroplasty, 2020, Volume: 35, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2020
Intravenous tranexamic acid vs. topical thrombin in total shoulder arthroplasty: a comparative study.
    Journal of shoulder and elbow surgery, 2021, Volume: 30, Issue:2

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, S

2021
Letter to the Editor on "Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Pain, Postope

2020
Author Response to Commentary on "Topical Tranexamic Acid Increases Early Postoperative Pain After Total Hip Arthroplasty".
    The Journal of arthroplasty, 2020, Volume: 35, Issue:9

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Pain, Postope

2020
The impact of tranexamic acid on administration of red blood cell transfusions for resection of colorectal liver metastases.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2021, Volume: 23, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Colorectal Neoplasms; Erythrocyte Transfusion; Hepate

2021
Prospective Study Assessing the Effect of Local Infiltration of Tranexamic Acid on Facelift Bleeding.
    Aesthetic surgery journal, 2021, 03-12, Volume: 41, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Case-Control Studies; Female

2021
Effect of Tranexamic Acid on Wound Complications and Blood Loss in Total Ankle Arthroplasty.
    Foot & ankle international, 2020, Volume: 41, Issue:9

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Ankle; Blood Loss, Surgical; Cohort Studie

2020
[Analysis of hemostatic effect and safety of tranexamic acid in primary simultaneous bilateral total hip arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Jul-15, Volume: 34, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemostatics; Humans;

2020
Efficacy of intravenous tranexamic acid administration in revision hip arthroplasty.
    Der Orthopade, 2021, Volume: 50, Issue:6

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2021
Tranexamic acid in hip hemiarthroplasty.
    Injury, 2020, Volume: 51, Issue:11

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Hemiarthropla

2020
Administration of tranexamic acid during total shoulder arthroplasty is not associated with increased risk of complications in patients with a history of thrombotic events.
    Journal of shoulder and elbow surgery, 2021, Volume: 30, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Databases,

2021
One Dose Versus Two Doses of Intravenous Tranexamic Acid in Total Joint Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2021, Jun-01, Volume: 29, Issue:11

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2021
Intraoperative coagulopathy during cesarean section as an unsuspected initial presentation of COVID-19: a case report.
    BMC pregnancy and childbirth, 2020, Aug-24, Volume: 20, Issue:1

    Topics: Adult; Antifibrinolytic Agents; Betacoronavirus; Blood Coagulation Disorders; Blood Loss, Surgical;

2020
Finding the optimal control level of intraoperative blood pressure in no tourniquet primary total knee arthroplasty combine with tranexamic acid: a retrospective cohort study which supports the enhanced recovery strategy.
    Journal of orthopaedic surgery and research, 2020, Aug-25, Volume: 15, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Pressure

2020
Higher doses of topical tranexamic acid safely improves immediate functional outcomes and reduces transfusion requirement in total knee arthroplasty.
    Archives of orthopaedic and trauma surgery, 2020, Volume: 140, Issue:12

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2020
Efficacy of topical versus intravenous tranexamic acid in spinal deformity.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020, Volume: 29, Issue:12

    Topics: Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Hu

2020
Effectiveness of administering tranexamic acid to high-risk hip and knee arthroplasty patients: a systematic review protocol.
    JBI evidence synthesis, 2020, Volume: 18, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2020
Effect of 3 different anticoagulants on hidden blood loss during total hip arthroplasty after tranexamic acid.
    Medicine, 2020, Sep-04, Volume: 99, Issue:36

    Topics: Administration, Intravenous; Aged; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacemen

2020
Efficacy and safety of tranexamic acid in unilateral major revision total hip arthroplasty.
    Annals of palliative medicine, 2020, Volume: 9, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Retrospective

2020
The effects of intravenous and local tranexamic acid on bone healing: An experimental study in the rat tibia fracture model.
    Injury, 2020, Volume: 51, Issue:12

    Topics: Administration, Intravenous; Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Rats; Tibia; Ti

2020
Does tourniquet use decrease blood loss following primary total knee arthroplasty in Jehovah's Witness patients?
    Joint diseases and related surgery, 2020, Volume: 31, Issue:3

    Topics: Aged; Anesthesia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fe

2020
Is tranexamic acid effective on hidden blood loss in patients during total knee arthroplasty?
    Joint diseases and related surgery, 2020, Volume: 31, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Component Transfusion; Blood L

2020
Is continuation of anti-platelet treatment safe for elective total hip arthroplasty patients?
    Archives of orthopaedic and trauma surgery, 2020, Volume: 140, Issue:12

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Aspirin; Blood Los

2020
Effectiveness of Multi-Modal Blood Management in Bernese Periacetabular Osteotomy and Periacetabular Osteotomy with Proximal Femoral Osteotomy.
    Orthopaedic surgery, 2020, Volume: 12, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Hip Dislocation, Congenital

2020
Does intraoperative transfusion during total knee arthroplasty reduce the need for transfusion after surgery?: A preliminary retrospective cohort study.
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2021, Volume: 28, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
Tranexamic acid in non-elective primary total hip arthroplasty.
    Injury, 2021, Volume: 52, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans; Male;

2021
Tranexamic Acid Administration is Associated With a Decreased Odds of Prosthetic Joint Infection Following Primary Total Hip and Primary Total Knee Arthroplasty: A National Database Analysis.
    The Journal of arthroplasty, 2021, Volume: 36, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2021
Tranexamic Acid in Infantile Craniosynostosis Surgery: Friend or Foe?
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Female; Humans;

2020
The Utility of Obtaining a Complete Blood Count After Total Knee Arthroplasty in the Era of Tranexamic Acid.
    Orthopedics, 2021, Jan-01, Volume: 44, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Cell

2021
[Acute Limb Ischemia after Total Hip Arthroplasty in a High-Risk Patient - Is Tranexamic Acid to Blame?]
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2020, Volume: 87, Issue:5

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2020
Intravenous tranexamic acid for reducing perioperative blood loss during revision hip arthroplasty: A retrospective study.
    Acta orthopaedica et traumatologica turcica, 2020, Volume: 54, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Su

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Does the correction angle affect hidden blood loss in HTO?
    Journal of orthopaedic surgery and research, 2020, Nov-11, Volume: 15, Issue:1

    Topics: Aged; Blood Loss, Surgical; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Ost

2020
Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study.
    BMC musculoskeletal disorders, 2020, Nov-12, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2020
Simultaneous Bilateral Primary Total Knee Arthroplasty With TXA and Restrictive Transfusion Protocols: Still a 1 in 5 Risk of Allogeneic Transfusion.
    The Journal of arthroplasty, 2021, Volume: 36, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2021
[Progress on the application of tranexamic acid in adolescent spine corrective surgery].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Nov-15, Volume: 34, Issue:11

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Postoperative

2020
Factors associated with blood loss in ankylosing spondylitis patients with hip involvement undergoing primary total hip arthroplasty: a cross-sectional retrospective study of 243 patients.
    Journal of orthopaedic surgery and research, 2020, Nov-18, Volume: 15, Issue:1

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Sedimentation; Cross-Sectio

2020
Routine Postoperative Complete Blood Counts Are Not Necessary After Most Primary Total Hip and Knee Arthroplasties.
    The Journal of arthroplasty, 2021, Volume: 36, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Cell

2021
[Efficacy and safety of tranexamic acid in total hip arthroplasty via direct anterior approach].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2020, Nov-25, Volume: 33, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Antiviral Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgica

2020
[Analysis of hemostatic effect of intra-articular injection of tranexamic acid after minimally invasive unicompartmental knee arthroplasty].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2020, Nov-25, Volume: 33, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Hemost

2020
Does tranexamic acid influence activated clotting time values in patients undergoing cardiac surgery?
    Journal of clinical anesthesia, 2022, Volume: 79

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Tranexamic Acid

2022
[Comparison of hemostatic effect and safety in primary unilateral total hip arthroplasty receiving different anticoagulants after anti-fibrinolysis with tranexamic acid].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Dec-15, Volume: 34, Issue:12

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemos

2020
[Perioperative blood management for total hip/knee arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, Dec-15, Volume: 34, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2020
Combined treatment of intraoperative cell-salvage and tranexamic acid for primary unilateral total hip arthroplasty: Are there added benefits?
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2022, Volume: 27, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Hu

2022
Tourniquetless Total Knee Arthroplasty: History, Controversies, and Technique.
    The Journal of the American Academy of Orthopaedic Surgeons, 2021, Jan-01, Volume: 29, Issue:1

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Knee Joint; Tourniquets; Tranexamic A

2021
Use of tranexamic acid is not associated with complications following bipolar hemiarthroplasty for metastatic disease.
    Journal of surgical oncology, 2021, Volume: 123, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Femoral Neoplasms; Femur Neck; Follow-Up Stud

2021
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre.
    Current oncology (Toronto, Ont.), 2020, Volume: 27, Issue:6

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnai

2020
Impact of Obesity on Tranexamic Acid Efficacy in Adult Patients With Major Bleeding.
    The Annals of pharmacotherapy, 2021, Volume: 55, Issue:9

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Obesity; Retrospective Stu

2021
Is there a role of tranexamic acid in rheumatoid arthritis with total knee arthroplasty? Findings from a multicenter prospective cohort study in China.
    Archives of orthopaedic and trauma surgery, 2021, Volume: 141, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; C

2021
Can Tranexamic Acid Be Safely Administered during Microsurgery in the Era of COVID-19?
    Plastic and reconstructive surgery, 2021, 03-01, Volume: 147, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; COVID-19; Humans; Microsurgery; Tranexamic Acid

2021
Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis.
    Aesthetic surgery journal, 2021, 06-14, Volume: 41, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Lipectomy; Postoperative Hemorrha

2021
Intravenous tranexamic acid is associated with safe reduced blood loss and transfusion rate in one-stage exchange for infected hip arthroplasty.
    Joint diseases and related surgery, 2021, Volume: 32, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Lo

2021
Intra-operative local plus systemic tranexamic acid significantly decreases post-operative bleeding and the need for allogeneic blood transfusion in total knee arthroplasty.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2021, 02-01, Volume: 18, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2021
The efficacy of intravenous tranexamic acid administration at induction in definitive hip fracture surgery: Is there a role?
    Injury, 2021, Volume: 52, Issue:8

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hum

2021
Does Not Use of Closed Suction Drainage in Total Knee Arthroplasty with Tranexamic Acid Reduce Blood Loss?
    Ortopedia, traumatologia, rehabilitacja, 2020, Oct-31, Volume: 22, Issue:5

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drainage; Female; Hu

2020
Do all cardiac surgery patients benefit from antifibrinolytic therapy?
    Journal of cardiac surgery, 2021, Volume: 36, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures;

2021
Variation in prophylactic tranexamic acid administration among anesthesiologists and surgeons in orthopedic surgery: a retrospective cohort study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021, Volume: 68, Issue:7

    Topics: Adult; Anesthesiologists; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgi

2021
Clinical Outcomes and Experience of a Multiyear Consecutive Case Series of Total Knee Arthroplasty Procedures Conducted with a Bipolar Sealer System for Hemostasis.
    The journal of knee surgery, 2022, Volume: 35, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Hemostasis; Humans;

2022
Predictors for blood loss and transfusion frequency to guide blood saving programs in primary knee- and hip-arthroplasty.
    Scientific reports, 2021, 02-23, Volume: 11, Issue:1

    Topics: Aged; Anemia; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bioma

2021
The efficiency and safety of intravenous tranexamic acid administration in open reduction and internal fixation of pelvic and acetabular fractures.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Pelvis; Tranexamic Acid

2022
Is tranexamic acid use in patients with a hip fracture safe?
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Denmark;

2021
Comparing the effect of tourniquet and tranexamic acid on the tibial cement mantle thickness in total knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoperativ

2022
Commentary on: Local Infiltration of Tranexamic Acid (TXA) in Liposuction: A Single-Surgeon Outcomes Analysis and Considerations for Minimizing Postoperative Donor Site Ecchymosis.
    Aesthetic surgery journal, 2021, 06-14, Volume: 41, Issue:7

    Topics: Blood Loss, Surgical; Ecchymosis; Humans; Lipectomy; Surgeons; Tranexamic Acid

2021
Associations of preoperative stroke and tranexamic acid administration with convulsive seizures in valvular open-heart surgery.
    Journal of anesthesia, 2021, Volume: 35, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Retrospective St

2021
A New Low Dose of Tranexamic Acid for Decreasing the Rate of Blood Loss in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
    Journal of pediatric orthopedics, 2021, Jul-01, Volume: 41, Issue:6

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Humans; Kyphosi

2021
Impact of tranexamic acid on blood loss and transfusion rate in children with cerebral palsy undergoing hip reconstruction with two or more osteotomies.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Ce

2022
Topical tranexemic acid reduces intra-operative blood loss and transfusion requirements in spinal deformity correction in patients with adolescent idiopathic scoliosis.
    Spine deformity, 2021, Volume: 9, Issue:5

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Scolio

2021
Tranexamic acid does not affect intraoperative blood loss or in-hospital outcomes after acetabular fracture surgery.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Hospitals; Humans; Middle Aged;

2022
Effect of administration of tranexamic acid on reduced risk of red blood cell transfusion after resection for colorectal liver metastases.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2021, Volume: 23, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Colorectal Neoplasms; Erythrocyte Transfusion; Humans

2021
Prophylactic tranexamic acid use in non-cardiac surgeries at high risk for transfusion.
    Transfusion medicine (Oxford, England), 2021, Volume: 31, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Canada; Humans; Retrospective Studies; Tranexamic Aci

2021
Safety and Efficacy of Topical Administration of Tranexamic Acid in High-Risk Patients Undergoing Posterior Lumbar Interbody Fusion Surgery.
    World neurosurgery, 2021, Volume: 151

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiovascular Disease

2021
Tranexamic Acid Is Safe in Patients with a History of Coronary Artery Disease Undergoing Total Joint Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2021, 05-19, Volume: 103, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2021
Tranexamic acid and the burden of early neurologic complications in valvular open-heart surgery: A propensity matched analysis in 3227 patients.
    Journal of clinical anesthesia, 2021, Volume: 73

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Humans; Tranexamic Acid

2021
ε-Aminocaproic acid versus tranexamic acid in children undergoing complex cranial vault reconstruction for repair of craniosynostosis.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:8

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Craniosynostoses; Humans; R

2021
Risk Factors for Increased Surgical Drain Output After Transforaminal Lumbar Interbody Fusion.
    World neurosurgery, 2021, Volume: 151

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Lumbar Verteb

2021
Tranexamic Acid in High-risk Arthroplasty Patients: How Will We Adapt to Evolving Evidence?
    Anesthesiology, 2021, 07-01, Volume: 135, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2021
[Tranexamic acid and arthroplasty: between off-label use and evidence-based medicine].
    Der Anaesthesist, 2021, Volume: 70, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Evidence-Based Medicine; Humans; Off-La

2021
Low blood transfusion rate after implementation of tranexamic acid for fast- track hip- and knee arthroplasty. An observational study of 5205 patients.
    Acta orthopaedica Belgica, 2021, Volume: 87, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2021
Efficacy of repeated intravenous tranexamic acid in reducing perioperative bleeding of acetabular fractures.
    Clinical hemorheology and microcirculation, 2021, Volume: 79, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa

2021
Blood management in direct anterior versus posterior primary total hip arthroplasty using tranexamic acid: a matched cohort study.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Cohort Studies; Human

2023
Efficacy and safety of tranexamic acid in hip fracture surgery: A comparative study of 613 patients.
    Journal of perioperative practice, 2022, Volume: 32, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2022
Benefits of Tranexamic Acid in Total Knee Arthroplasty: A Classification and Regression Tree Analysis in Function of Instrumentation, BMI, and Gender.
    The journal of knee surgery, 2023, Volume: 36, Issue:2

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2023
Efficacy and Safety of Tranexamic Acid in Resection and Endoprosthetic Reconstruction of Distal Femoral Osteosarcomas in Children: A Retrospective Cohort Study.
    Journal of pediatric orthopedics, 2021, Sep-01, Volume: 41, Issue:8

    Topics: Administration, Intravenous; Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Femal

2021
The Use of Tranexamic Acid in Facial Cosmetic Surgery Procedures: A Technical Note.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2021, Volume: 79, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Humans; Surgery, Plastic; Tranexamic Acid

2021
Population Pharmacokinetics of Intra-articular and Intravenous Administration of Tranexamic Acid in Patients Undergoing Total Knee Replacement.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2022
The Efficacy and Safety of Tranexamic Acid Treatment in Orthopaedic Trauma Surgery.
    JBJS reviews, 2021, 07-16, Volume: 9, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Orthopedics; Tranexamic Acid

2021
High- versus low-dose tranexamic acid as part of a Patient Blood Management strategy for reducing blood loss in patients undergoing surgery for adolescent idiopathic scoliosis.
    Spine deformity, 2022, Volume: 10, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Humans; Retrospective

2022
[Study on the safety and effectiveness of low-dose tranexamic acid in operation of multi-level continuous thoracic ossification of ligament flavum].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2021, Jul-15, Volume: 35, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Ligaments; Osteogenesis; Postoperative Hemorr

2021
[Application of tranexamic acid in the treatment of intertrochanteric fracture of femur].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2021, Jul-25, Volume: 34, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Femur; Hip Fractures; Humans; Postoperative Hemorrhag

2021
Tranexamic acid is safe and effective in patients with heterozygous factor V Leiden mutation during total joint arthroplasty.
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement,

2023
Effectiveness of using tranexamic acid in total hip and total knee arthroplasty: Single tertiary center experience.
    Saudi medical journal, 2021, Volume: 42, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2021
Effect of administration of tranexamic acid on reduced risk of red blood cell transfusion after resection for colorectal liver metastases - Reply.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2021, Volume: 23, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Colorectal Neoplasms; Erythrocyte Transfusion; Humans

2021
Efficacy and Safety of Locally Injected Tranexamic Acid in Hip Fracture Patients: A Retrospective Review.
    Journal of orthopaedic trauma, 2022, Mar-01, Volume: 36, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hip Fractures; Humans; Retrospective Studies; Tranexa

2022
Thrombotic activation before and after total hip arthroplasty. A prospective cohort study.
    BMC musculoskeletal disorders, 2021, Aug-13, Volume: 22, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2021
Comparison of topical and intravenous Tranexamic acid for high tibial osteotomy: A retrospective study.
    Medicine, 2021, Aug-13, Volume: 100, Issue:32

    Topics: Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Follow-

2021
In reply to the letter to the editor regarding "The efficacy and safety of tranexamic acid in high tibial osteotomy: a systematic review and meta-analysis".
    Journal of orthopaedic surgery and research, 2021, 08-16, Volume: 16, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Osteotomy; Tranexamic Acid

2021
Significantly reducing blood loss via a peri-articular injection of tranexamic acid during total knee arthroplasty: a retrospective study.
    BMC musculoskeletal disorders, 2021, Aug-17, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2021
Tranexamic Acid is Associated With Decreasing the Risk of Complications in Patients Undergoing Arthroplasty With Preoperative Coagulopathy.
    The Journal of arthroplasty, 2021, Volume: 36, Issue:12

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Human

2021
Effect and safety of topical application of tranexamic acid to reduce perioperative blood loss in elderly patients with intertrochanteric fracture undergoing PFNA.
    Medicine, 2021, Aug-27, Volume: 100, Issue:34

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blo

2021
Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:7

    Topics: Adolescent; Anaphylaxis; Anesthesia, General; Anesthesia, Intravenous; Antifibrinolytic Agents; Bloo

2017
Effect of Tranexamic Acid on Transfusion Rates Following Total Joint Arthroplasty: A Cost and Comparative Effectiveness Analysis.
    The Orthopedic clinics of North America, 2017, Volume: 48, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2017
CORR Insights
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Tranexamic A

2017
Process Improvement Project Using Tranexamic Acid Is Cost-Effective in Reducing Blood Loss and Transfusions After Total Hip and Total Knee Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:8

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2017
Tranexamic Acid and Computer-Assisted Surgery in Cemented and Cementless Total Knee Arthroplasty: Are the Effects Additive for Blood Conservation?
    Surgical technology international, 2017, Jul-25, Volume: 30

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Bloodle

2017
Invited Commentary related to: Tranexamic Acid Safely Reduced Blood Lossin Hemi- and Total Hip Arthroplasty for Acute Femoral Neck Fracture: A Randomized Clinical Trial.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:7

    Topics: Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Femoral Neck Fractures; Humans; Tranexamic Aci

2017
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
    The New England journal of medicine, 2017, 05-11, Volume: 376, Issue:19

    Topics: Antifibrinolytic Agents; Arteries; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass;

2017
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
    The New England journal of medicine, 2017, 05-11, Volume: 376, Issue:19

    Topics: Antifibrinolytic Agents; Arteries; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass;

2017
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
    The New England journal of medicine, 2017, 05-11, Volume: 376, Issue:19

    Topics: Antifibrinolytic Agents; Arteries; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass;

2017
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
    The New England journal of medicine, 2017, 05-11, Volume: 376, Issue:19

    Topics: Antifibrinolytic Agents; Arteries; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass;

2017
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
    The New England journal of medicine, 2017, 05-11, Volume: 376, Issue:19

    Topics: Antifibrinolytic Agents; Arteries; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass;

2017
Tranexamic Acid Effectively Reduces Blood Loss and Transfusion Rates during Simultaneous Bilateral Total Knee Arthroplasty.
    The journal of knee surgery, 2018, Volume: 31, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2018
Tranexamic Acid Reduces Blood Loss in Craniosynostosis Surgery.
    The Journal of craniofacial surgery, 2017, Volume: 28, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Critical Care; H

2017
An Aprotinin Containing Fibrin Sealant Does Not Reduce Blood Loss in Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:11

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Aprotinin; Arthroplasty, Replacement, Hip; Blo

2017
Tranexamic Acid: What Is Known and Unknown, and Where Do We Go From Here?
    Anesthesiology, 2017, Volume: 127, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2017
Oral Tranexamic Acid Reduces Transfusions in Total Knee Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2017
What Should Define Preoperative Anemia in Primary THA?
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:11

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Loss, Surgical;

2017
Limitations of Preoperative PFA-200 as a Predictor of Postoperative Blood Loss in Total Knee Arthroplasty: According to Use of Tranexamic Acid.
    Clinical laboratory, 2017, Jul-01, Volume: 63, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Loss, Surgical; Blood Tr

2017
Use of a Tourniquet in Total Knee Arthroplasty Causes a Paradoxical Increase in Total Blood Loss.
    The Journal of bone and joint surgery. American volume, 2017, Aug-16, Volume: 99, Issue:16

    Topics: Aged; Analysis of Variance; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Su

2017
A new topical hemostatic agent TT-173 reduces blood loss in a sheep model of total knee arthroplasty.
    The Knee, 2017, Volume: 24, Issue:6

    Topics: Animals; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2017
Periarticular Injection of Tranexamic Acid Reduces Blood Loss and the Necessity for Allogeneic Transfusion After Total Knee Arthroplasty Using Autologous Transfusion: A Retrospective Observational Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2018
[Local Application of Tranexamic Acid in Total Hip Arthroplasty Decreases Blood Loss and Consumption of Blood Transfusion].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2017, Volume: 84, Issue:4

    Topics: Administration, Cutaneous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss

2017
Tranexamic Acid Should be Considered in Fracture Surgery.
    Journal of orthopaedic trauma, 2017, Volume: 31, Issue:10

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Routes; Fracture Fixation; Fractu

2017
Epsilon Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Hip and Total Knee Arthroplasty.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:1

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
Comparison of Oral and Intravenous Tranexamic Acid for Prevention of Perioperative Blood Loss in Total Knee and Total Hip Arthroplasty.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Repl

2018
Topical use of tranexamic acid can effectively decrease hidden blood loss during posterior lumbar spinal fusion surgery: A retrospective study.
    Medicine, 2017, Volume: 96, Issue:42

    Topics: Administration, Topical; Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusi

2017
Can Tranexamic Acid Reduce Blood Loss during Major Cardiac Surgery? A Pilot Study.
    Annals of clinical and laboratory science, 2017, Volume: 47, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Valve Annuloplasty; Corona

2017
Perioperative Blood Loss and Transfusion in Craniosynostosis Surgery.
    The Journal of craniofacial surgery, 2018, Volume: 29, Issue:1

    Topics: Adolescent; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Craniotomy; Female; Hematocri

2018
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
    Journal of pediatric orthopedics, 2017, Volume: 37, Issue:8

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R

2017
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
    Journal of pediatric orthopedics, 2017, Volume: 37, Issue:8

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R

2017
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
    Journal of pediatric orthopedics, 2017, Volume: 37, Issue:8

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R

2017
High-dose Versus Low-dose Tranexamic Acid to Reduce Transfusion Requirements in Pediatric Scoliosis Surgery.
    Journal of pediatric orthopedics, 2017, Volume: 37, Issue:8

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Dose-Response R

2017
Evaluating the Effect on Mortality of a No-Tranexamic acid (TXA) Policy for Cardiovascular Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiovascular Surgical Procedures; Cohort Stud

2018
Craniosynostosis Surgery and the Impact of Tranexamic Acid Dosing.
    The Journal of craniofacial surgery, 2018, Volume: 29, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Craniosynostoses; Dr

2018
Risk Factors for Reaching the Post-Operative Transfusion Trigger in a Community Primary Total Knee Arthroplasty Population.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2018
Benefits of Tranexamic Acid Not Debatable but Leave Tourniquet Use to Surgeon's Discretion: Commentary on an article by ZeYu Huang, MD, PhD, et al.: "Intravenous and Topical Tranexamic Acid Alone Are Superior to Tourniquet Use for Primary Total Knee Arthr
    The Journal of bone and joint surgery. American volume, 2017, 12-20, Volume: 99, Issue:24

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2017
Tranexamic Acid Use in Cardiac Surgery: Hemostasis, Seizures, or a Little of Both.
    Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Hemostasis; Humans; Seiz

2018
Clinical Research of Combined Intravenous Administration and Topical Application of Tranexamic Acid to a Surgical Wound During Posterior Lumbar Fusion.
    Surgical innovation, 2018, Volume: 25, Issue:2

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Sur

2018
Comment on Chiem J, Ivanova I, Jimenez N. Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
    Paediatric anaesthesia, 2018, Volume: 28, Issue:2

    Topics: Adolescent; Anaphylaxis; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Scoliosis; Spinal Fu

2018
From Foundation to Demolition: The Influence of Perioperative Tranexamic Acid.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemostasis; Humans; Perioperative Care; Tranexamic Ac

2018
Tranexamic acid may result in small decrease in blood loss in patients undergoing orthognathic surgery.
    Journal of the American Dental Association (1939), 2018, Volume: 149, Issue:4

    Topics: Blood Loss, Surgical; Double-Blind Method; Humans; Orthognathic Surgery; Orthognathic Surgical Proce

2018
The effect of tranexamic acid in unilateral and bilateral total knee arthroplasty in the South Asian population: A retrospective cohort study.
    International journal of surgery (London, England), 2018, Volume: 52

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Asian People; Blood Loss, Surgical;

2018
Evidence appraisal of Kim C, Park SS, Dhotar HS, Perruccio AV, Zywiel MG, Davey JR. Topical tranexamic acid reduces transfusion rates in simultaneous bilateral total knee arthroplasty: a retrospective case series. Can J Surg. 2017;60(5):311-315.
    AORN journal, 2018, Volume: 107, Issue:3

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Humans; Retrospective Stud

2018
Effectiveness and safety of an optimized blood management program in total hip and knee arthroplasty: A large, single-center, retrospective study.
    Medicine, 2018, Volume: 97, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Adult; Aged; Anemia; Antifibrinolytic Agents;

2018
Additional Dose of Intravenous Tranexamic Acid after Primary Total Knee Arthroplasty Further Reduces Hidden Blood Loss.
    Chinese medical journal, 2018, Mar-20, Volume: 131, Issue:6

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans; Male; Middle Aged; Pilo

2018
Incidence and Risk Factors for Blood Transfusion in Simultaneous Bilateral Total Joint Arthroplasty: A Multicenter Retrospective Study.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical;

2018
Improved Early Postoperative Range of Motion in Total Knee Arthroplasty Using Tranexamic Acid: A Retrospective Analysis.
    The journal of knee surgery, 2019, Volume: 32, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies

2019
Matched cohort study of topical tranexamic acid in cementless primary total hip replacement.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:7

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2018
[A case report of tranexamic acid associated epilepsy in spine surgery].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2018, Mar-25, Volume: 31, Issue:3

    Topics: Blood Loss, Surgical; Epilepsy; Humans; Orthopedic Procedures; Spine; Tranexamic Acid

2018
Pharmacologic Hemostatic Agents in Total Joint Arthroplasty-A Cost-Effectiveness Analysis.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
Supportive topical tranexamic acid application for hemostasis in oral bleeding events - Retrospective cohort study of 542 patients.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2018, Volume: 46, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Anticoagulants; Blood

2018
Aprotinin and coronary artery bypass surgery.
    European journal of anaesthesiology, 2018, Volume: 35, Issue:1

    Topics: Aprotinin; Blood Loss, Surgical; Coronary Artery Bypass; Humans; Tranexamic Acid

2018
Intravenous tranexamic acid only versus combined intravenous and intra-articular tranexamic acid for perioperative blood loss in patients undergoing total knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:7

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2018
Effect of Tranexamic Acid on Blood Loss, D-Dimer, and Fibrinogen Kinetics in Adult Spinal Deformity Surgery.
    The Journal of bone and joint surgery. American volume, 2018, May-02, Volume: 100, Issue:9

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Female; Fibrin Fibrinoge

2018
Minimizing Blood Loss and Transfusions in Total Knee Arthroplasty.
    The journal of knee surgery, 2018, Volume: 31, Issue:7

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Epoetin Alfa; Fibrin Tissu

2018
[Effect on time of temporarily-closed wound drainage on blood loss of primary total knee arthroplasty after intravenous and intra-articular injection of tranexamic acid].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2017, 04-15, Volume: 31, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; D

2017
Tranexamic acid administration to older patients undergoing primary total hip arthroplasty conserves hemoglobin and reduces blood loss.
    Canadian journal of surgery. Journal canadien de chirurgie, 2018, Volume: 61, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood

2018
Blood Loss Reduction with Tranexamic Acid and a Bipolar Sealer in Direct Anterior Total Hip Arthroplasty.
    American journal of orthopedics (Belle Mead, N.J.), 2018, Volume: 47, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2018
Effectiveness of a patient blood management protocol on reduction of allogeneic red blood cell transfusions in orthopedic surgery.
    Medicina clinica, 2019, 02-01, Volume: 152, Issue:3

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplas

2019
Transfusion rate using intravenous tranexamic acid in hip revision surgery.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2018
Intravenous Tranexamic Acid before and after Tourniquet Use Can Reduce Blood Loss and Blood Transfusion after Total Knee Arthroplasty
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2016, Volume: 99, Issue:11

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2016
When Should Complete Blood Count Tests Be Performed in Primary Total Hip Arthroplasty Patients?
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blo

2018
Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study.
    Journal of orthopaedic surgery and research, 2018, Jun-18, Volume: 13, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Coagulation; Blood

2018
Response to Letter to the Editor on "The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis".
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2018
Letter to the Editor on "The Safety of Tranexamic Acid in Total Joint Arthroplasty: A Direct Meta-Analysis".
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Humans; Tranexamic Acid

2018
Reply: The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 142, Issue:3

    Topics: Blood Loss, Surgical; Humans; Plastics; Tranexamic Acid

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 142, Issue:3

    Topics: Blood Loss, Surgical; Humans; Plastics; Tranexamic Acid

2018
One Dose of Intravenous Tranexamic Acid Is Equivalent to Two Doses in Total Hip and Knee Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2018, Jul-05, Volume: 100, Issue:13

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthropl

2018
Should we use prophylactic tranexamic acid in orthognathic surgery to decrease blood loss?
    International journal of oral and maxillofacial surgery, 2018, Volume: 47, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthognathic Surgery; Tranexamic Acid

2018
The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study.
    International journal of oral and maxillofacial surgery, 2018, Volume: 47, Issue:11

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Osteotomy; Tranexamic Ac

2018
Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis.
    BMC musculoskeletal disorders, 2018, Jul-18, Volume: 19, Issue:1

    Topics: Administration, Topical; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2018
Comment on: "Efficacy of preoperative administration of single high dose intravenous tranexamic acid in reducing blood loss in total knee arthroplasty: A prospective clinical study".
    Acta orthopaedica et traumatologica turcica, 2018, Volume: 52, Issue:4

    Topics: Administration, Intravenous; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Humans; Postoper

2018
Patients With Infected Total Hip Arthroplasty Undergoing 2-Stage Exchange Arthroplasty Experience Massive Blood Loss.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Arthroplasty, Replacement, Hip; Blood Loss, S

2018
The Effect of Preoperative Administration of Intravenous Tranexamic Acid During Revision Hip Arthroplasty: A Retrospective Study.
    The Journal of bone and joint surgery. American volume, 2018, Sep-05, Volume: 100, Issue:17

    Topics: Acetabulum; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood

2018
Tranexamic Acid Reduces Perioperative Blood Loss and Hemarthrosis in Total Ankle Arthroplasty.
    American journal of orthopedics (Belle Mead, N.J.), 2018, Volume: 47, Issue:8

    Topics: Aged; Ankle Joint; Antifibrinolytic Agents; Arthroplasty, Replacement, Ankle; Blood Loss, Surgical;

2018
Tranexamic acid is effective for blood management in open-wedge high tibial osteotomy.
    Orthopaedics & traumatology, surgery & research : OTSR, 2018, Volume: 104, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Case-Control Studies

2018
Early morbidity and mortality after single-stage bilateral total knee replacement.
    Orthopaedics & traumatology, surgery & research : OTSR, 2018, Volume: 104, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2018
The key role of tranexamic acid in Patient Blood Management programmes.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Tranexamic Ac

2018
Ulnar Artery Thrombosis Following Tranexamic Acid Administration for Craniosynostosis Repair.
    The Journal of craniofacial surgery, 2019, Volume: 30, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child, Preschool; Craniosynostoses; Female; Humans; T

2019
Topical Tranexamic Acid in Revision Total Knee Arthroplasty Reduces Transfusion Rates and May Be Associated With Earlier Recovery.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:7S

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2019
Effect of pharmacist intervention on blood conservation therapy in total knee arthroplasty: A retrospective, observational study.
    Basic & clinical pharmacology & toxicology, 2019, Volume: 124, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2019
Transfusion rates with intravenous tranexamic acid in total hip arthroplasty performed using the direct anterior approach.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2019, Volume: 29, Issue:5

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Antiviral Agents; Arthroplasty, Replacem

2019
Comparison of three routes of administration of tranexamic acid in primary unilateral total knee arthroplasty: Analysis of a national database.
    Thrombosis research, 2019, Volume: 173

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2019
The efficacy and safety of tranexamic acid in reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis: A retrospective observational study.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Bone Transplantation; China; Decom

2018
Routine Postoperative Laboratory Tests Are Not Necessary After Primary Total Hip Arthroplasty.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Aged; Anemia; Arthroplasty, Replacement, Hip; Blood Chemical Analysis; Blood Lo

2019
Blood loss of total knee arthroplasty in osteoarthritis: an analysis of influential factors.
    Journal of orthopaedic surgery and research, 2018, Dec-22, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement,

2018
[Preliminary analysis of the effect of different administration routes of tranexamic acid on blood loss after total hip arthroplasty for female femur neck fractures].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2018, Dec-25, Volume: 31, Issue:12

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2018
Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection.
    BioMed research international, 2018, Volume: 2018

    Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female;

2018
Total Knee Arthroplasty Is Safe in Jehovah's Witness Patients-A 12-Year Perspective.
    The journal of knee surgery, 2020, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Los

2020
Tranexamic acid is effective in lower doses with infusion in total knee arthroplasty.
    Acta orthopaedica et traumatologica turcica, 2019, Volume: 53, Issue:2

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2019
Does Prophylactic Administration of TXA Reduce Mean Operative Time and Postoperative Blood Loss in Posterior Approach Lumbar Spinal Fusion Surgery Performed for Degenerative Spinal Disease?
    Clinical spine surgery, 2019, Volume: 32, Issue:7

    Topics: Blood Loss, Surgical; Female; Humans; Intervertebral Disc Degeneration; Lumbar Vertebrae; Male; Oper

2019
Role of intravenous tranexamic acid in reducing blood loss during caesarean section: Study at tribal-dominated area hospital in Chhattisgarh, India.
    The journal of obstetrics and gynaecology research, 2019, Volume: 45, Issue:4

    Topics: Administration, Intravenous; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section;

2019
The Efficacy and Safety of Prophylactic Intravenous Tranexamic Acid on Perioperative Blood Loss in Patients Treated with Posterior Lumbar Interbody Fusion.
    World neurosurgery, 2019, Volume: 125

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion, Autologous; Body Mass Index; Bone

2019
Orthotopic liver transplantation in a patient receiving apixaban for portal vein thrombosis.
    Journal of clinical anesthesia, 2019, Volume: 56

    Topics: Aged; Blood Loss, Surgical; Carcinoma, Hepatocellular; Dabigatran; Humans; Infusions, Intravenous; L

2019
Perioperative intravenous tranexamic acid reduces blood transfusion in primary cementless total hip arthroplasty.
    Acta bio-medica : Atenei Parmensis, 2019, 01-10, Volume: 90, Issue:1-S

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2019
Do tourniquet and drainage influence fast track in total knee arthroplasty? Our results on 151 cases.
    Acta bio-medica : Atenei Parmensis, 2019, 01-10, Volume: 90, Issue:1-S

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2019
Tranexamic Acid Reduces Transfusion Rates in Obese Patients Undergoing Total Joint Arthroplasty.
    Surgical technology international, 2019, May-15, Volume: 34

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgica

2019
Letter to the Editor Regarding "The Efficacy of Tranexamic Acid on Blood Loss of Lumbar Spinal Fusion Surgery: A Meta-Analysis of Randomized Controlled Trials".
    World neurosurgery, 2019, Volume: 122

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Randomized Controlled Trials as Topic; Spinal

2019
    Zeitschrift fur Orthopadie und Unfallchirurgie, 2019, Volume: 157, Issue:1

    Topics: Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Pyrazines; Retrospective Studies; Tran

2019
[Case-control study on effect of early intermittently closing drainage tube for blood loss after total knee arthroplasty].
    Zhongguo gu shang = China journal of orthopaedics and traumatology, 2019, Jan-25, Volume: 32, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2019
Postoperative thrombotic effects of tranexamic acid in open heart surgery.
    Irish journal of medical science, 2019, Volume: 188, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Ca

2019
A survey of anaesthetists' use of tranexamic acid in noncardiac surgery.
    Anaesthesia and intensive care, 2019, Volume: 47, Issue:1

    Topics: Anesthetists; Antifibrinolytic Agents; Australia; Blood Loss, Surgical; Humans; New Zealand; Randomi

2019
[Effect of tranexamic acid on blood loss and soft-tissue swelling following cemented total hip replacement].
    Orvosi hetilap, 2019, Volume: 160, Issue:12

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Humans; Length of Sta

2019
Effects of topical tranexamic acid during open reduction and internal fixation of acetabular fractures: A retrospective study.
    Acta orthopaedica et traumatologica turcica, 2019, Volume: 53, Issue:3

    Topics: Acetabulum; Administration, Topical; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio

2019
Reducing transfusion requirements following total knee arthroplasty: effectiveness of a double infusion of tranexamic acid.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:5

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2019
The effects of tranexamic acid on blood loss and transfusion rate in colorectal surgery.
    American journal of surgery, 2019, Volume: 218, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Colectomy; Drug Admin

2019
Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study.
    Neurosurgical focus, 2019, 04-01, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Co

2019
Clinical Impact of Routine Complete Blood Counts Following Total Knee Arthroplasty.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:7S

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Cel

2019
Utilization and Real-world Effectiveness of Tranexamic Use in Shoulder Arthroplasty: A Population-based Study.
    The Journal of the American Academy of Orthopaedic Surgeons, 2019, Oct-01, Volume: 27, Issue:19

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, Surgical; Blood Tran

2019
[Evaluation of Efficacy of Systemic Administration of Tranexamic Acid (Exacyl) in Total Hip and Knee Arthroplasty - Prospective Cohort Study].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2019, Volume: 86, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2019
Topical tranexamic acid in elderly patients with femoral neck fractures treated with hemiarthroplasty: efficacy and safety? - a case-control study.
    BMC musculoskeletal disorders, 2019, May-17, Volume: 20, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion; Case-Cont

2019
Intravenous tranexamic acid safely and effectively reduces transfusion rates in revision total hip arthroplasty.
    The bone & joint journal, 2019, Volume: 101-B, Issue:6_Supple_B

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2019
Minimizing transfusion in sagittal craniosynostosis surgery: the Children's Hospital of Minnesota Protocol.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019, Volume: 35, Issue:8

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Clinical Protocols; Cranios

2019
Short-term safety of tranexamic acid use in posterior cervical decompression and fusion surgery.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 66

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Ce

2019
Tranexamic Acid in Thoracic and Lumbar Fusions and Perioperative Blood Loss.
    Clinical spine surgery, 2019, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Loss, Surgical; Dose-Response Relationship, Drug;

2019
Tibial cement mantle thickness is not affected by tourniquetless total knee arthroplasty when performed with tranexamic acid.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020, Volume: 28, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Bone Cements;

2020
Blood loss and perioperative transfusions related to surgery for spinal tumors. Relevance of tranexamic acid.
    Neuro-Chirurgie, 2019, Volume: 65, Issue:6

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Decompression, Surgic

2019
The use of tranexamic acid in adult spinal deformity: is there an optimal dosing strategy?
    The spine journal : official journal of the North American Spine Society, 2019, Volume: 19, Issue:10

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Male; Middl

2019
Implementation of tranexamic acid reduces red blood cell utilization in orthopedic surgeries.
    Transfusion, 2019, Volume: 59, Issue:9

    Topics: Academic Medical Centers; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgi

2019
Optimal route for administering tranexamic acid in primary unilateral total hip arthroplasty: Results from a multicenter cohort study.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:9

    Topics: Administration, Intravenous; Administration, Topical; Aged; Anticoagulants; Antifibrinolytic Agents;

2019
Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study.
    BMC musculoskeletal disorders, 2019, Jun-28, Volume: 20, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Tra

2019
The efficacy and safety of tranexamic acid for reducing blood loss following simultaneous bilateral total knee arthroplasty: a multicenter retrospective study.
    BMC musculoskeletal disorders, 2019, Jul-12, Volume: 20, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2019
Intraarticular use of tranexamic acid reduces blood loss and transfusion rate after primary total knee arthroplasty.
    BMC musculoskeletal disorders, 2019, Jul-27, Volume: 20, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2019
Balancing thrombotic and bleeding risks related to antiplatelet therapy in coronary bypass surgery: Comment on "Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting".
    JAMA surgery, 2013, Volume: 148, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Female; Humans;

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
The effect of tranexamic acid on blood loss and transfusion rate in primary total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:7

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2013
[Intravenous administration of tranexamic acid to decrease bleeding and transfusion in knee and hip prosthetic surgery: is it safe and cost-effective?].
    Medicina clinica, 2013, Sep-07, Volume: 141, Issue:5

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Cost-Benefit

2013
Inadequate methodology renders results on the use of tranexamic acid inconclusive.
    International orthopaedics, 2013, Volume: 37, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans; Male

2013
Tranexamic acid for reducing blood transfusions in arthroplasty interventions: a cost-effective practice.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014, Volume: 24, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2014
Reply to Letter to the Editor: Inadequate methodology renders results on the use of tranexamic acid inconclusive.
    International orthopaedics, 2013, Volume: 37, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans; Male

2013
The effect of tranexamic acid on transfusion rate in primary total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2014
The effect of tranexamic acid on transfusion rate in primary total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2014
The effect of tranexamic acid on transfusion rate in primary total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2014
The effect of tranexamic acid on transfusion rate in primary total hip arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Repl

2014
Preliminary results suggest tranexamic acid is safe and effective in arthroplasty patients with severe comorbidities.
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplast

2014
Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2013
Cerebrovascular infarction following bilateral total knee arthroplasty and tranexamic acid administration.
    Acta orthopaedica Belgica, 2013, Volume: 79, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Cerebral Infar

2013
Tranexamic acid and thrombosis.
    Prescrire international, 2013, Volume: 22, Issue:140

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hematuria; Hemorrhage; Humans; Menorrhagia; R

2013
One dose of tranexamic acid is safe and effective in revision knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2013
Trauma and tranexamic acid.
    The Medical journal of Australia, 2013, Sep-02, Volume: 199, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Thrombosis; Tranexamic Acid; Woun

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
An evaluation of the use of topical tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2013, Volume: 28, Issue:8 Suppl

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2013
Tranexamic acid decreases risk of haematomas but not pain after hip arthroplasty.
    Orthopaedics & traumatology, surgery & research : OTSR, 2013, Volume: 99, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss

2013
Evaluation of the efficacy and safety of tranexamic acid for reducing blood loss in bilateral total knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:3

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2014
Topical tranexamic acid reduces transfusion rates in total hip and knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:4

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Repl

2014
Tranexamic Acid Tamponade to Control Postoperative Surgical Hemorrhage.
    The Journal of oral implantology, 2015, Volume: 41, Issue:3

    Topics: Anticoagulants; Blood Loss, Surgical; Humans; Postoperative Hemorrhage; Tooth Extraction; Tranexamic

2015
[Percutaneous nephrolithotomy - tranexamic acid reduces blood loss].
    Aktuelle Urologie, 2013, Volume: 44, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male; Nephrostomy, Percutaneous; Tran

2013
Tranexamic acid reduces surgical bleeding: does one size fit all?
    Evidence-based medicine, 2014, Volume: 19, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2014
Blood transfusion after primary total knee arthroplasty can be significantly minimised through a multimodal blood-loss prevention approach.
    International orthopaedics, 2014, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2014
[Intravenous tranexamic acid in primary total knee arthroplasty].
    Medicina clinica, 2014, Nov-07, Volume: 143, Issue:9

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Hemostatics;

2014
Blood conservation.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32 Suppl 1

    Topics: Anesthesia; Antifibrinolytic Agents; Arthritis, Infectious; Arthroplasty, Replacement; Blood Loss, S

2014
Can tranexamic acid and hydrogen peroxide reduce blood loss in cemented total knee arthroplasty?
    Archives of orthopaedic and trauma surgery, 2014, Volume: 134, Issue:7

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2014
Usefulness of intraoperative continuous infusion of tranexamic acid during emergency surgery for type A acute aortic dissection.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2015, Volume: 21, Issue:1

    Topics: Acute Disease; Aged; Antifibrinolytic Agents; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Lo

2015
Cost benefit analysis of topical tranexamic acid in primary total hip and knee arthroplasty.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty

2014
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Tranexamic acid and trauma.
    The Medical journal of Australia, 2014, Mar-17, Volume: 200, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Hemorrhage; Humans; Tranexamic Acid; Wounds and Injur

2014
Healthy ethical conduct is vital.
    Acta obstetricia et gynecologica Scandinavica, 2014, Volume: 93, Issue:4

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; China; Comorbidity; Computer

2014
Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplast

2015
Perioperative tranexamic acid in day-case paediatric tonsillectomy.
    Annals of the Royal College of Surgeons of England, 2014, Volume: 96, Issue:2

    Topics: Adolescent; Ambulatory Surgical Procedures; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Ch

2014
What is the evidence for tranexamic acid in burns?
    Burns : journal of the International Society for Burn Injuries, 2014, Volume: 40, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Burns; Hemorrhage; Humans; Tranexamic Acid

2014
Use of tranexamic acid in infants undergoing choroid plexus papilloma surgery: a report of two cases.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:7

    Topics: Blood Loss, Surgical; Blood Volume; Choroid Plexus Neoplasms; Female; Hemostatics; Humans; Infant; I

2014
Tranexamic acid reduces intraoperative blood loss in orthognathic surgery.
    Evidence-based dentistry, 2014, Volume: 15, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Orthognathic Surgical Procedures; Randomized

2014
The effects of Amicar and TXA on lumbar spine fusion in an animal model.
    Spine, 2014, Sep-01, Volume: 39, Issue:19

    Topics: Aminocaproic Acid; Animals; Antifibrinolytic Agents; Blood Loss, Surgical; Calcification, Physiologi

2014
Decreased blood transfusion following revision total knee arthroplasty using tranexamic acid.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:9 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2014
Eliminating transfusion in primary joint arthroplasty-an achievable goal.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Blood Transfusion; Goals; Humans; Trane

2014
Comparison of intra-operative regimes of tranexamic acid administration in primary total hip replacement.
    Acta orthopaedica Belgica, 2014, Volume: 80, Issue:2

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.
    BMJ (Clinical research ed.), 2014, Aug-12, Volume: 349

    Topics: Adult; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Kne

2014
Tranexamic acid for surgical bleeding.
    BMJ (Clinical research ed.), 2014, Aug-13, Volume: 349

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2014
Efficacy and safety of tranexamic acid versus ϵ-aminocaproic acid in cardiovascular surgery.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiopul

2014
Does tranexamic acid improve outcomes in patients undergoing urgent or emergency surgery?
    Annals of emergency medicine, 2015, Volume: 65, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Emergencies; Humans; Tranexamic Acid

2015
Cost analysis of use of tranexamic Acid to prevent major bleeding complications in hip and knee arthroplasty surgery.
    American journal of orthopedics (Belle Mead, N.J.), 2014, Volume: 43, Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2014
Assessment of the introduction of a blood management program in orthopaedic surgery.
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:8

    Topics: Aged; Anemia; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biomarkers; Blood Ban

2015
Topical versus intravenous tranexamic acid in total knee arthroplasty.
    The Journal of arthroplasty, 2015, Volume: 30, Issue:3

    Topics: Administration, Intravenous; Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, R

2015
Evaluating the safety and efficacy of tranexamic acid administration in pediatric cranial vault reconstruction.
    The Journal of craniofacial surgery, 2015, Volume: 26, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child, Preschool; Cohort Studies;

2015
Topical tranexamic Acid does not affect electrophysiologic or neurovascular sciatic nerve markers in an animal model.
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:3

    Topics: Administration, Topical; Animals; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Los

2015
[Blood loss during total knee-joint replacement: a combination of anticoagulant and hemostatic techniques].
    Khirurgiia, 2014, Issue:12

    Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Etha

2014
[Effectiveness of tranexamic acid in total knee arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2014, Volume: 28, Issue:11

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2014
Topical tranexamic acid was noninferior to intravenous tranexamic acid in controlling blood loss during total knee arthroplasty.
    The Journal of bone and joint surgery. American volume, 2015, Feb-18, Volume: 97, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Humans; Male

2015
Eliminating the use of allogeneic blood products in adolescent idiopathic scoliosis surgery.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25 Suppl 1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hemoglobins; H

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study.
    Journal of orthopaedic surgery and research, 2015, Mar-28, Volume: 10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
Does Tranexamic Acid Reduce Blood Loss and Transfusion Requirements Associated With the Periacetabular Osteotomy?
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:8

    Topics: Acetabulum; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Dru

2015
Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value.
    The Journal of arthroplasty, 2015, Volume: 30, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
The value of tranexamic acid during fronto-orbital advancement in isolated metopic craniosynostosis.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2015, Volume: 43, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Female; Humans;

2015
[The Use of Thromboelastometry and Tranexamic Acid Reduces Blood Loss and Transfusion Requirements in Cardiac Surgery under Cardiopulmonary Bypass].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:2

    Topics: Aged; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Cardiopulmonary Bypass;

2015
The efficacy of tranexamic acid in hip hemiarthroplasty surgery: an observational cohort study.
    Injury, 2015, Volume: 46, Issue:10

    Topics: Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Hemiarthroplasty; Hip Frac

2015
Tranexamic Acid Decreases Incidence of Blood Transfusion in Simultaneous Bilateral Total Knee Arthroplasty.
    The Journal of arthroplasty, 2015, Volume: 30, Issue:12

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2015
Universal tranexamic acid therapy to minimize transfusion for major joint arthroplasty: a retrospective analysis of protocol implementation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2015, Volume: 62, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2015
CORR Insights(®): Does Tranexamic Acid Reduce Blood Loss and Transfusion Requirements Associated With the Periacetabular Osteotomy?
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:11

    Topics: Acetabulum; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Hip Dislocatio

2015
Minimizing Blood Transfusion in Total Hip and Knee Arthroplasty Through a Multimodal Approach.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:2

    Topics: Aged; Aged, 80 and over; Algorithms; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip

2016
The Use of Intravenous Tranexamic Acid in Patients Undergoing Total Hip or Knee Arthroplasty: A Retrospective Analysis at a Single Military Institution.
    Military medicine, 2015, Volume: 180, Issue:10

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2015
Intravenous administration of tranexamic acid effectively reduces blood loss in primary total knee arthroplasty in a 610-patient consecutive case series.
    Transfusion, 2016, Volume: 56, Issue:2

    Topics: Administration, Intravenous; Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Female; Hu

2016
An In Vivo Study of Low-Dose Intra-Articular Tranexamic Acid Application with Prolonged Clamping Drain Method in Total Knee Replacement: Clinical Efficacy and Safety.
    BioMed research international, 2015, Volume: 2015

    Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drainage; Female; Humans; Injections, I

2015
Cost Analysis of Tranexamic Acid in Anemic Total Joint Arthroplasty Patients.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:3

    Topics: Aged; Anemia; Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Blood Transfusion; Cost-B

2016
Tranexamic acid reduces the blood loss and blood transfusion requirements following peri-acetabular osteotomy.
    The bone & joint journal, 2015, Volume: 97-B, Issue:12

    Topics: Acetabulum; Adolescent; Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Fem

2015
Tranexamic acid decreases blood loss after total shoulder arthroplasty.
    Journal of shoulder and elbow surgery, 2016, Volume: 25, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement; Blood Loss, Surgical; Blood Transfusion; Female;

2016
Intra-articular tranexamic acid wash during bilateral total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2015, Volume: 23, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2015
Comparison between topical and intravenous administration of tranexamic acid in primary total hip arthroplasty.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:1

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2016
Does tranexamic acid reduce blood loss and transfusion rates in unicompartmental knee arthroplasty?
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; F

2016
"Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial".
    The Journal of arthroplasty, 2016, Volume: 31, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Cost-effectiveness of post-operative cell salvage in total knee arthroplasty. Should we continue to recommend its use today?
    Revista espanola de anestesiologia y reanimacion, 2016, Volume: 63, Issue:8

    Topics: Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Autolog

2016
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:4

    Topics: Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Is there a need for routine post-operative hemoglobin level estimation in total knee arthroplasty with tranexamic acid use?
    The Knee, 2016, Volume: 23, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2016
Tranexamic acid: optimal blood loss management in surface replacement arthroplasty.
    The bone & joint journal, 2016, Volume: 98-B, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2016
Low dose tranexamic acid reduces blood transfusion rate after total knee arthroplasty: A population-based study in Taiwan.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2017, Volume: 116, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
Beware of using tranexamic acid in parturients with eclampsia.
    Anaesthesia, critical care & pain medicine, 2016, Volume: 35, Issue:3

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Critical Care; Eclampsia; Fe

2016
In Reply: Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood

2016
Letter to the Editor on "Tranexamic Acid Benefits Total Joint Arthroplasty Patients Regardless of Preoperative Hemoglobin Value".
    The Journal of arthroplasty, 2016, Volume: 31, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood

2016
Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:7

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty; Aspirin; Blood Loss, Surgical; Cohort Studies; Female;

2016
A protocol for management of blood loss in surgical treatment of peritoneal malignancy by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
    Transfusion medicine (Oxford, England), 2016, Volume: 26, Issue:2

    Topics: Blood Component Transfusion; Blood Loss, Surgical; Cytoreduction Surgical Procedures; Factor VIII; F

2016
Tranexamic acid in total joint arthroplasty.
    ANZ journal of surgery, 2016, Volume: 86, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty; Arthroplasty, Replacement; Blood Loss, Surgical; Humans; Post

2016
Low-volume formulation of intra-articular tranexamic acid, 25-ml tranexamic acid (2.5 g) plus 20-ml saline, is effective in decreasing blood transfusion rate in primary total knee replacement even without preoperative haemoglobin optimization.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2016
Bleeding complications during cardiac electronic device implantation in patients receiving antithrombotic therapy: is there any value of local tranexamic acid?
    BMC cardiovascular disorders, 2016, Apr-22, Volume: 16

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Chi-Square Distributio

2016
Tranexamic acid decreases blood loss in total shoulder arthroplasty and reverse total shoulder arthroplasty.
    Journal of shoulder and elbow surgery, 2016, Volume: 25, Issue:10

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Shoulder; Blood Loss, S

2016
Announcing the winner of the John J. Sciarra IJGO Prize Paper Award for 2015.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016, Volume: 133, Issue:3

    Topics: Awards and Prizes; Blood Loss, Surgical; Cesarean Section; Female; Gynecology; History, 21st Century

2016
Efficacy of tranexamic acid in reducing allogeneic blood products in adolescent idiopathic scoliosis surgery.
    BMC musculoskeletal disorders, 2016, Apr-27, Volume: 17

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Male;

2016
Commentary: Clinical and financial benefits of intra-articular tranexamic acid in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2016
Letter to the Editor: Intra-articular tranexamic acid wash during bilateral total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2016
Letter to the Editor: Intra-articular tranexamic acid wash during bilateral total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2016
Tranexamic Acid in Hip and Knee Arthroplasty.
    The Journal of the American Academy of Orthopaedic Surgeons, 2016, Volume: 24, Issue:6

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2016
Multimodal blood loss prevention approach including intra-articular tranexamic acid in primary total knee arthroplasty for patients with severe haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2016, Volume: 22, Issue:4

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies

2016
Comparison of ε-Aminocaproic Acid and Tranexamic Acid in Reducing Postoperative Transfusions in Total Hip Arthroplasty.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:12

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgic

2016
Controversy in Tranexamic Acid Administration Route Continues: Commentary on an article by Zeng Yi, MD, et al.: "Tranexamic Acid Administration in Primary Total Hip Arthroplasty: A Randomized Controlled Trial of Intravenous Combined with Topical Versus Si
    The Journal of bone and joint surgery. American volume, 2016, 06-15, Volume: 98, Issue:12

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture patients.
    BMJ open, 2016, 06-21, Volume: 6, Issue:6

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusi

2016
Effect of Antifibrinolytic Therapy on Complications, Thromboembolic Events, Blood Product Utilization, and Fusion in Adult Spinal Deformity Surgery.
    Spine, 2016, Jul-15, Volume: 41, Issue:14

    Topics: Adult; Aged; Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Female; Humans; Male;

2016
Intravenous versus topical tranexamic acid administration in primary total knee arthroplasty: a meta-analysis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017, Volume: 25, Issue:11

    Topics: Administration, Intravenous; Administration, Topical; Antifibrinolytic Agents; Arthroplasty, Replace

2017
The Efficacy Comparison of Tranexamic Acid for Reducing Blood Loss in Total Knee Arthroplasty at Different Dosage Time.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:1

    Topics: Administration, Intravenous; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood L

2017
Blood-Sparing Efficacy of Oral Tranexamic Acid in Primary Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:1

    Topics: Administration, Oral; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Sur

2017
Tranexamic Acid in Anesthetic Management of Surgical Procedures.
    AANA journal, 2016, Volume: 84, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Contr

2016
Prophylactic use of tranexamic acid combined with thrombelastogram guided coagulation management may reduce blood loss and allogeneic transfusion in pediatric hemispherectomy: case series.
    Journal of clinical anesthesia, 2016, Volume: 33

    Topics: Algorithms; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Child, Preschoo

2016
Implementation of a Tranexamic Acid Protocol to Reduce Blood Loss During Cranial Vault Remodeling for Craniosynostosis.
    The Journal of craniofacial surgery, 2016, Volume: 27, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Craniosynostoses; Hemorrhage; Humans; Infant; Postope

2016
Effects of tranexamic acid on coagulation indexes of patients undergoing heart valve replacement surgery under cardiopulmonary bypass.
    International journal of immunopathology and pharmacology, 2016, Volume: 29, Issue:4

    Topics: Adolescent; Blood Coagulation; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary By

2016
Topical Tranexamic Acid in Total Knee Arthroplasty Patients with Increased Thromboembolic Risk.
    The journal of knee surgery, 2017, Volume: 30, Issue:5

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss,

2017
The Michigan Experience with Safety and Effectiveness of Tranexamic Acid Use in Hip and Knee Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2016, 10-05, Volume: 98, Issue:19

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bloo

2016
Tranexamic acid use and risk of thrombosis in regular users ofantithrombotics undergoing primary total knee arthroplasty: a prospectivecohort study.
    Blood transfusion = Trasfusione del sangue, 2018, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fibrinolytic Agents;

2018
Influence of single-dose intravenous tranexamic acid on total hip replacement : A study on transfusions, collateral complications, and readmissions.
    Der Orthopade, 2017, Volume: 46, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Argentina; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Bloo

2017
Re: Efficacy and Safety of Intraoperative Tranexamic Acid Infusion for Reducing Blood Transfusion during Open Radical Cystectomy.
    The Journal of urology, 2016, Volume: 196, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cystectomy; Humans; Tranexamic Aci

2016
Rapid hemostasis in a sheep model using particles that propel thrombin and tranexamic acid.
    The Laryngoscope, 2017, Volume: 127, Issue:4

    Topics: Animals; Blood Loss, Surgical; Carotid Artery Injuries; Disease Models, Animal; Hemostatic Technique

2017
High-dose tranexamic acid reduces intraoperative and postoperative blood loss in posterior lumbar interbody fusion.
    Journal of neurosurgery. Spine, 2017, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Case-Cont

2017
Lower red cell transfusion rates with use of tranexamic acid in single-stage bilateral total knee arthroplasty: A retrospective audit.
    JPMA. The Journal of the Pakistan Medical Association, 2016, Volume: 66(Suppl 3), Issue:10

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; H

2016
Topical Tranexamic Acid is Equivalent to Targeted Preoperative Autologous Blood Donation in Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplas

2017
Prospective observational study of the effect of dual antiplatelet therapy with tranexamic acid treatment on platelet function and bleeding after cardiac surgery.
    British journal of anaesthesia, 2016, Volume: 117, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Platelets; Card

2016
Intraarticular Administration of Tranexamic Acid is Safe and Effective in Total Knee Arthroplasty Patients at High-Risk for Thromboembolism.
    Surgical technology international, 2016, Dec-16, Volume: 30

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss

2016
[Intra-Articular Application of Tranexamic Acid Significantly Reduces Blood Loss and Transfusion Requirement in Primary Total Knee Arthroplasty].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2016, Volume: 83, Issue:4

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Arthritis; Arthroplasty, Replacement, Knee;

2016
Tranexamic acid versus fibrin sealant in primary total hip replacement: a comparative study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017, Volume: 27, Issue:7

    Topics: Aerosols; Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood

2017
Can tranexamic acid reduce blood loss in cervical laminectomy with lateral mass screw fixation and bone grafting: a retrospective observational study.
    Medicine, 2017, Volume: 96, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Bone Screws; Bone Transplantation; Cervical Ver

2017
The Effectiveness and Safety of Tranexamic Acid in Orthotopic Liver Transplantation Clinical Practice: A Propensity Score Matched Cohort Study.
    Transplantation, 2017, Volume: 101, Issue:7

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Databases, Factual; Erythrocyte Transfusion; Female;

2017
Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery.
    Journal of thrombosis and thrombolysis, 2017, Volume: 43, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Area Under Curve; Blood Loss, Surgical; Coronary Artery Bypass; Creat

2017
Tranexamic acid: still far to go.
    British journal of anaesthesia, 2017, 03-01, Volume: 118, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2017
Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:3

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Cooperati

2017
Reply to letter to the editor on "Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: A double-blinded randomised controlled noninferiority trial".
    The Knee, 2017, Volume: 24, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2017
Letter to editor "Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: A double-blinded randomized controlled noninferiority trial".
    The Knee, 2017, Volume: 24, Issue:3

    Topics: Administration, Intravenous; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, S

2017
Aprotinin is not associated with postoperative renal impairment after primary coronary surgery.
    The Annals of thoracic surgery, 2008, Volume: 86, Issue:1

    Topics: Acute Kidney Injury; Aged; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Case-Control Studies;

2008
Perioperative coagulation management and blood conservation in cardiac surgery: a Canadian Survey.
    Journal of cardiothoracic and vascular anesthesia, 2008, Volume: 22, Issue:5

    Topics: Anticoagulants; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Heparin; Human

2008
A questionnaire-based survey of perioperative blood conservation practice for revision hip arthroplasty in Scotland.
    Transfusion medicine (Oxford, England), 2008, Volume: 18, Issue:5

    Topics: Anesthesia; Anesthesiology; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Sur

2008
Routine preoperative coagulation screening detects a rare bleeding disorder.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:1

    Topics: Antifibrinolytic Agents; Blood Component Transfusion; Blood Loss, Surgical; Child; Factor X Deficien

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Bleeding in liver surgery: prevention and treatment.
    Clinics in liver disease, 2009, Volume: 13, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Hemostatics; Hepat

2009
Living without aprotinin: the results of a 5-year blood saving program in cardiac surgery.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:5

    Topics: Adult; Aged; Anticoagulants; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Blood Loss, Surg

2009
Antifibrinolytic therapy in complex spine surgery: a case-control study comparing aprotinin and tranexamic acid.
    Orthopedics, 2009, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion

2009
Perioperative haemostatic management of Glanzmann thrombasthenia for abdominal surgery.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusion, Au

2009
Optimization of recovering shed blood when performing blood salvage.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion, Autologous; Cardiac Surgical Proce

2009
[Type A hemophilia in a man undergoing liver resection for metastasis: implications for anesthetic management].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:3

    Topics: Adenocarcinoma; Aged; Anesthesia, General; Blood Loss, Surgical; Colorectal Neoplasms; Deamino Argin

2009
[Tranexamic acid and dentoalveolar surgery].
    Ugeskrift for laeger, 2009, May-18, Volume: 171, Issue:21

    Topics: Anticoagulants; Blood Loss, Surgical; Fibrinolytic Agents; Hemostatics; Humans; Oral Surgical Proced

2009
eComment: A comparison of the safety of aprotinin and tranexamic acid in cardiac surgery.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:1

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Proced

2009
Recombinant activated factor VII and tranexamic acid are haemostatically effective during major surgery in factor XI-deficient patients with inhibitor antibodies.
    Thrombosis and haemostasis, 2009, Volume: 102, Issue:3

    Topics: Alleles; Blood Loss, Surgical; Factor VIIa; Factor XI; Factor XI Deficiency; Female; Hemophilia A; H

2009
Acute myocardial infarction in a patient with hemophilia A and factor V Leiden mutation.
    Cardiology journal, 2009, Volume: 16, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Antifibrinolytic Agents; Blood Loss, Surgical; Coagulants; Coronary

2009
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study. Spine 2008; 33: 2577-80.
    Spine, 2009, Jul-15, Volume: 34, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Humans; Orthopedic Procedures; P

2009
The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery.
    Anesthesia and analgesia, 2010, Jan-01, Volume: 110, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiop

2010
Pneumatic wound compression after hip fracture surgery.
    Acta orthopaedica, 2009, Volume: 80, Issue:5

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Bandages; Blood Loss, Surgical; Fracture Fi

2009
High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Proc

2010
High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Proc

2010
High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Proc

2010
High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Proc

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
One intraoperative dose of tranexamic Acid for patients having primary hip or knee arthroplasty.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:7

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2010
Can we safely reduce blood loss during lumbar pedicle subtraction osteotomy procedures using tranexamic acid or aprotinin? A comparative study with controls.
    Spine, 2010, Jan-15, Volume: 35, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Female; Hemostatics; Humans;

2010
Can we safely reduce blood loss during lumbar pedicle subtraction osteotomy procedures using tranexamic acid or aprotinin? A comparative study with controls.
    Spine, 2010, Jan-15, Volume: 35, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Female; Hemostatics; Humans;

2010
Can we safely reduce blood loss during lumbar pedicle subtraction osteotomy procedures using tranexamic acid or aprotinin? A comparative study with controls.
    Spine, 2010, Jan-15, Volume: 35, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Female; Hemostatics; Humans;

2010
Can we safely reduce blood loss during lumbar pedicle subtraction osteotomy procedures using tranexamic acid or aprotinin? A comparative study with controls.
    Spine, 2010, Jan-15, Volume: 35, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Female; Hemostatics; Humans;

2010
A single centre experience in circumcision of haemophilia patients: Izmir protocol.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2010, Volume: 16, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Circumcision, Male; Factor I

2010
Tranexamic acid reduces allogenic transfusion in revision hip arthroplasty.
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2011
Tranexamic acid: how much is enough?
    Anesthesia and analgesia, 2010, Volume: 111, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Dose-Response Relationsh

2010
Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis.
    Critical care (London, England), 2010, Volume: 14, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiop

2010
Tranexamic acid: an alternative to aprotinin as antifibrinolytic therapy in pediatric congenital heart surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 39, Issue:4

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Proced

2011
Efficient strategy for controlling postoperative hemorrhage in total knee arthroplasty.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2011, Volume: 19, Issue:6

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Arthroplasty, Replacement, Knee; Blood Loss, Surgical

2011
ε-Aminocaproic acid and clinical value in cardiac anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Algorithms; Aminocaproic Acid; Anesthesia; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical;

2011
Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients.
    The Annals of thoracic surgery, 2010, Volume: 90, Issue:5

    Topics: Adult; Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Endarterectomy; Female; Hemos

2010
Removal of aprotinin from low-dose aprotinin/tranexamic acid antifibrinolytic therapy increases transfusion requirements in cardiothoracic surgery.
    Interactive cardiovascular and thoracic surgery, 2011, Volume: 12, Issue:2

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Blood Loss, Surgical; Blood Transfusion

2011
Blood conservation and pain control in scoliosis corrective surgery: an online survey of UK practice.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:1

    Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthesia; Anticoagulants; Antifibrinolytic Ag

2011
Blood conservation in cardiac surgery.
    Journal of perioperative practice, 2010, Volume: 20, Issue:12

    Topics: Algorithms; Aprotinin; Blood Loss, Surgical; Blood Substitutes; Blood Transfusion; Cardiac Surgical

2010
The post-BART anti-fibrinolytic dilemma?
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Proced

2011
Seizures after open heart surgery: comparison of ε-aminocaproic acid and tranexamic acid.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Aged; Aminocaproic Acid; Anesthesia; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical

2011
Conference discussion: Removal of aprotinin from low-dose aprotinin/tranexamic acid antifibrinolytic therapy increases transfusion requirements in cardiothoracic surgery.
    Interactive cardiovascular and thoracic surgery, 2011, Volume: 12, Issue:2

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass;

2011
Comparison of blood-sparing efficacy of ε-aminocaproic acid and tranexamic acid in newborns undergoing cardiac surgery.
    The Thoracic and cardiovascular surgeon, 2011, Volume: 59, Issue:5

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgica

2011
Use of tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement.
    Journal of orthopaedic surgery and research, 2011, May-21, Volume: 6

    Topics: Antifibrinolytic Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgica

2011
rFVIIa administered by continuous infusion during surgery in patients with severe congenital FVII deficiency.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2011, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Blood Loss, Surgical; Factor VII Deficiency; Factor VIIa; Female; Hemostasis, Sur

2011
Is tranexamic acid really an alternative to aprotinin?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 41, Issue:2

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Female; Heart

2012
Use of tranexamic acid as a rescue measure to achieve hemostasis after massive blood loss in a pediatric neurosurgical patient.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:4

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Choroid Plexus Neoplasms; Female; Hemostasis; Humans;

2011
Comparative analysis of tranexamic acid use in minimally invasive versus open craniosynostosis procedures.
    The Journal of craniofacial surgery, 2011, Volume: 22, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Chi-Square Distribution; Child; Craniosynostoses; Fem

2011
Use of tranexamic acid to reduce bleeding in burns surgery.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2012, Volume: 65, Issue:5

    Topics: Bandages; Blood Loss, Surgical; Burns; Craniocerebral Trauma; Humans; Male; Middle Aged; Neck Injuri

2012
Are antifibrinolytics helpful in decreasing blood loss and transfusions during spinal fusion surgery in children with cerebral palsy scoliosis?
    Spine, 2012, Apr-20, Volume: 37, Issue:9

    Topics: Adolescent; Aminocaproic Acid; Analysis of Variance; Antifibrinolytic Agents; Blood Loss, Surgical;

2012
Efficacy of tranexamic acid in reducing blood loss in posterior lumbar spine surgery for degenerative spinal stenosis with instability: a retrospective case control study.
    BMC surgery, 2011, Nov-03, Volume: 11

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Decompression, Surgical; Dose-Response Relation

2011
Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:5

    Topics: Age Factors; Analysis of Variance; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac

2012
Randomised surgical trials need good surgical outcomes in the control arm.
    BMJ (Clinical research ed.), 2011, Nov-22, Volume: 343

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Male; Prostatectomy; Tranexamic Acid

2011
Use of tranexamic acid in pediatric cardiac surgery: we really need more.
    Journal of anesthesia, 2012, Volume: 26, Issue:2

    Topics: Blood Loss, Surgical; Cardiac Surgical Procedures; Female; Humans; Male; Postoperative Hemorrhage; T

2012
[Tranexamic acid reduces blood loss after major elective orthopaedic operations].
    Ugeskrift for laeger, 2012, Jan-09, Volume: 174, Issue:1-2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Loss

2012
Reducing blood losses and transfusion requirements in craniosynostosis surgery: an endless quest?
    Anesthesiology, 2012, Volume: 116, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Craniosynostoses; Elective Surgica

2012
Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2012, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Aprotinin; Blood Loss, Surgical; Female; Hemostasis, Surgical; Hemostatics;

2012
Effectiveness of tranexamic acid in revision total knee arthroplasty.
    Acta orthopaedica Belgica, 2012, Volume: 78, Issue:1

    Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgi

2012
Tranexamic acid for reduction of blood loss during total hip arthroplasty.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2012
Tranexamic acid for reduction of blood loss during total hip arthroplasty.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2012
Tranexamic acid for reduction of blood loss during total hip arthroplasty.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2012
Tranexamic acid for reduction of blood loss during total hip arthroplasty.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:10

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Female; Humans;

2012
Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis?
    Spine, 2012, Oct-01, Volume: 37, Issue:21

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Child; Female; Humans;

2012
Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery.
    Orthopaedics & traumatology, surgery & research : OTSR, 2012, Volume: 98, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplast

2012
Tranexamic acid reduces blood transfusion in surgical patients while its effects on thromboembolic events and mortality are uncertain.
    Evidence-based medicine, 2013, Volume: 18, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Tranexamic Acid

2013
Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures.
    Spine, 2012, Nov-01, Volume: 37, Issue:23

    Topics: Adolescent; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfus

2012
[Pharmacological reduction of bleeding during hip endoprosthetic replacement].
    Orvosi hetilap, 2012, Oct-14, Volume: 153, Issue:41

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss,

2012
A retrospective analysis of blood loss with combined topical and intravenous tranexamic acid after coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:1

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Cohort Studies; Corona

2013
Coronary artery bypass grafting after aprotinin: are we doing better?
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 145, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary B

2013
The risks associated with aprotinin use: a retrospective study of cardiac cases in Nova Scotia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:1

    Topics: Aged; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical

2013
Does tranexamic acid reduce blood loss and blood transfusion requirement in knee arthroplasty?
    Eklem hastaliklari ve cerrahisi = Joint diseases & related surgery, 2012, Volume: 23, Issue:3

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; F

2012
The routine use of tranexamic acid in hip and knee replacements.
    Bulletin of the NYU hospital for joint diseases, 2012, Volume: 70, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biom

2012
[Perioperative management based on kinetics of bleeding during total primary arthroplasty].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:3

    Topics: Aged; Anesthesia, General; Anesthesia, Spinal; Anticoagulants; Arthroplasty, Replacement, Hip; Arthr

2013
Repeat-dose intravenous tranexamic acid further decreases blood loss in total knee arthroplasty.
    International orthopaedics, 2013, Volume: 37, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfus

2013
[Anesthetic management of a patient with congenital plasminogen activator inhibitor-1 deficiency].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:1

    Topics: Adult; Anesthesia, General; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Male; Molar, Thir

2003
[Protocol for adapting treatment with vitamin K antagonists before dental extraction].
    Revue de stomatologie et de chirurgie maxillo-faciale, 2003, Volume: 104, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Blood Loss, Sur

2003
[Tranexamic acid versus aprotinin for the prevention of bleeding during mitral valve surgery ].
    Annales de cardiologie et d'angeiologie, 2003, Volume: 52, Issue:2

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiopulmonary Bypass; Dose-Respon

2003
[Acute normovolemic hemodilution combined with inhibition of fibrinolysis and use of cell saver in total hip arthroplasty].
    Ugeskrift for laeger, 2003, Jun-16, Volume: 165, Issue:25

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Blood Transfusion; Bl

2003
The use of tranexamic acid to reduce blood loss during total knee arthroplasty.
    The Knee, 2003, Volume: 10, Issue:4

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Bone Cements;

2003
Comment on "Clinical observation of blood loss reduced by tranexamic acid during and after cesarian section: a multi-center, randomized trial (Eur J Obstet Gynecol Reprod Biol 2004; 112: 154-57)".
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Oct-15, Volume: 116, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Cesarean Section; Female; Humans; Multicenter Studies

2004
More information on patients with factor XI deficiency.
    Anesthesiology, 2004, Volume: 101, Issue:5

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Factor XI Deficiency; Hemostasis; Humans; Postoperati

2004
Identifying patients at risk of intraoperative and postoperative transfusion in isolated CABG: toward selective conservation strategies.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Anticoagulants; Blood Component Transfusion; Bloo

2004
Continuous infusion of factor VIIIc during heart surgery in a patient with haemophilia A.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:12

    Topics: Anticoagulants; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Coronary

2004
Antifibrinolytic use and bleeding during surgery on the descending thoracic aorta: a multivariate analysis.
    Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:4

    Topics: Aged; Aminocaproic Acid; Antifibrinolytic Agents; Aortic Aneurysm, Thoracic; Blood Loss, Surgical; D

2005
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
The risk associated with aprotinin in cardiac surgery.
    The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4

    Topics: Adult; Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Pr

2006
[Hemostatic drugs in a patient with antiphospholipid syndrome and clinically significant perioperative bleeding].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:3

    Topics: Adult; Aminocaproic Acid; Antiphospholipid Syndrome; Aprotinin; Blood Coagulation Tests; Blood Loss,

2006
Management of the dental patient on anticoagulant medication.
    Dentistry today, 2006, Volume: 25, Issue:8

    Topics: Anticoagulants; Bleeding Time; Blood Coagulation Disorders; Blood Loss, Surgical; Dental Care for Ch

2006
[The "Seville" Consensus Document on Alternatives to Allogenic Blood Transfusion. Sociedades españolas de Anestesiología (SEDAR), Medicina Intensiva (SEMICYUC), Hematología y Hemoterapia (AEHH), Transfusión sanguínea (SETS) Trombosis y Hemostasia (SETH)].
    Medicina clinica, 2006, Jul-18, Volume: 127 Suppl 1

    Topics: Aminocaproic Acid; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Substitutes; Bloo

2006
Pro: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:6

    Topics: Aminocaproic Acid; Animals; Aprotinin; Blood Loss, Surgical; Cardiac Surgical Procedures; Drug Hyper

2006
Antifibrinolytic therapy use to mitigate blood loss during staged complex major spine surgery: Postoperative visual color changes after tranexamic acid administration.
    Anesthesiology, 2006, Volume: 105, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Chordoma; Color Perception; Color Vision Defects; Hum

2006
Topical use of tranexamic acid to control perioperative local bleeding in gynaecology patients with clotting disorders: two cases.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2007, Volume: 13, Issue:1

    Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Coagulation Diso

2007
Recombinant activated factor VII and epsilon aminocaproic acid treatment of a patient with Glanzmann's thrombasthenia for nasal polipectomy.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Adult; Aminocaproic Acid; Anesthesia, General; Antifibrinolytic Agents; Blood Loss, Surgical; Drug T

2007
Recombinant activated factor VII for hemostatic cover of orthopedic interventions in a girl with thrombocytopenia with absent radii syndrome.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:2

    Topics: Adolescent; Blood Loss, Surgical; Blood Platelet Disorders; Drug Administration Schedule; Factor VII

2007
Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusions for duchenne muscular dystrophy scoliosis.
    Spine, 2007, Sep-15, Volume: 32, Issue:20

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Child; E

2007
Practice pearl: a novel use of tranexamic Acid for decreasing the blood loss of aneurysmal bone cyst ablation.
    Annals of surgical oncology, 2008, Volume: 15, Issue:1

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Bone Cysts, Aneurysmal; Humans; Tranexamic Acid

2008
[Antifibrinolytic agents and repeat open-heart surgery: a comparison of tranexamic acid and low dose aprotinin].
    Annales de cardiologie et d'angeiologie, 2007, Volume: 56, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical

2007
[A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2008, Volume: 55, Issue:1

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Dietary Supplements; Epoetin Alfa; Erythr

2008
Effect of aprotinin on renal dysfunction in patients undergoing on-pump and off-pump cardiac surgery: a retrospective observational study.
    Lancet (London, England), 2008, Feb-09, Volume: 371, Issue:9611

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surg

2008
Does perioperative use of aprotinin reduce the rejection rate in heart transplant recipients?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2008, Volume: 33, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Female; Follow-Up Studies; Graft Re

2008
Re: Shapiro F, Zurakowski D, Sethna NF. Tranexamic acid diminishes intraoperative blood loss and transfusion in spinal fusion for Duchenne muscular dystrophy scoliosis. Spine 2007;32:2278-83.
    Spine, 2008, Apr-01, Volume: 33, Issue:7

    Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Child; E

2008
[Effectiveness of tranexamic acid in routine performance of total knee replacement surgery].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:2

    Topics: Aged; Aged, 80 and over; Aminocaproic Acid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee

2008
[Drugs to reduce transfusion needs during surgery].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2008, Apr-03, Volume: 128, Issue:7

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Auto

2008
Does tranexamic acid reduce blood loss in knee arthroplasty?
    The American journal of knee surgery, 1995,Summer, Volume: 8, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Chi-Square Distribution; Fem

1995
Drugs for surgical blood loss.
    Lancet (London, England), 1993, Jun-26, Volume: 341, Issue:8861

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Serine Proteinase Inhibitors; Tranexamic Acid

1993
Prevention of postbypass bleeding with tranexamic acid and epsilon-aminocaproic acid.
    Journal of cardiothoracic and vascular anesthesia, 1993, Volume: 7, Issue:4

    Topics: Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Coronary Artery

1993
Tranexamic acid use during coronary artery bypass grafting.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:2

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Chi-Square Distribution; Coronary Artery Bypass; Fibr

1996
Cost/benefit analysis of pharmacologic hemostasis.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:2 Suppl

    Topics: Aminocaproic Acid; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Cost-

1996
Tranexamic acid reduces blood loss after knee arthroplasty.
    The Journal of bone and joint surgery. British volume, 1996, Volume: 78, Issue:6

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Knee Prosthesis; Postoperative Complications;

1996
Tranexamic acid in the management of postpartum haemorrhage.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:12

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Critical Care; Female; Humans; Placenta Accreta; Post

1996
Tranexamic acid in the management of postpartum haemorrhage.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:12

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Critical Care; Female; Humans; Placenta Accreta; Post

1996
Tranexamic acid in the management of postpartum haemorrhage.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:12

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Critical Care; Female; Humans; Placenta Accreta; Post

1996
Tranexamic acid in the management of postpartum haemorrhage.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:12

    Topics: Adult; Blood Loss, Surgical; Cesarean Section; Critical Care; Female; Humans; Placenta Accreta; Post

1996
[Mouth-washing with tranexamic acid in patients treated with oral anticoagulants subjected to oral surgery procedures].
    Investigacion clinica, 1998, Volume: 39, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Loss, Surgical; Dental S

1998
[Can drugs reduce the need for blood transfusion in the course of surgery?].
    Ugeskrift for laeger, 1999, Jan-25, Volume: 161, Issue:4

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Deamino Arginine Vasopr

1999
Tranexamic acid applied topically to achieve haemostasis.
    Anaesthesia, 2000, Volume: 55, Issue:6

    Topics: Administration, Topical; Aged; Antifibrinolytic Agents; Blood Loss, Surgical; Hemostasis, Surgical;

2000
Is tranexamic acid indicated for total knee replacement surgery?
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Hemodilution; Humans

2000
Antifibrinolytic therapy reduces blood loss in knee replacement surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Hemodilution; Humans

2000
Recombinant FVIIa (NovoSeven) continuous infusion and total hip replacement in patients with haemophilia and high titre of inhibitors to FVIII: experience of two cases.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2000, Volume: 6, Issue:5

    Topics: Adult; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Factor VIIa; Factor VIII; Hemophilia A;

2000
Preservation of collagen-induced whole blood platelet aggregation by tranexamic acid therapy in primary cardiac valve surgery.
    Perfusion, 2000, Volume: 15, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiopulmonary Bypass; Collagen; Female; Hear

2000
Plasma tranexamic acid concentrations during cardiopulmonary bypass.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:5

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardiopulmonary B

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Drug Administrat

2001
The use of technologies to decrease peri-operative allogenic blood transfusion: results of practice variation in Israel.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:11

    Topics: Aprotinin; Attitude of Health Personnel; Biomedical Technology; Blood Loss, Surgical; Blood Transfus

2001
Intramedullary multiple hematomas in siblings with congenital alpha-2-plasmin inhibitor deficiency: orthopedic surgery with protection by tranexamic acid.
    Haemostasis, 1991, Volume: 21, Issue:5

    Topics: Adolescent; alpha-2-Antiplasmin; Blood Loss, Surgical; Bone Diseases; Child; Female; Femur; Hematoma

1991