Page last updated: 2024-11-05

tranexamic acid and Aneurysm, Ruptured

tranexamic acid has been researched along with Aneurysm, Ruptured in 12 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"Rebleeding from a ruptured aneurysm increases the risk of unfavorable outcomes after subarachnoid hemorrhage (SAH) and is prevented by early aneurysm occlusion."5.91Effects of Tranexamic Acid in Patients with Subarachnoid Hemorrhage in Brazil: A Prospective Observational Study with Propensity Score Analysis. ( Bastos, LSL; Bozza, FA; Gomes, FK; Gonçalves, B; Hegele, V; Kurtz, P; Petterson, L; Rabinstein, AA; Righy, C; Rynkowski, CB; Soares, PHR; Tonello, ML; Turon, R, 2023)
"Tranexamic acid treatment was without side effects and was given in standard doses until closure of the aneurysm or alternatively up to three days after the initial bleeding."2.43["Ultra-early" antifibrinolytic treatment of subarachnoidal bleeding with tranexamic acid]. ( Astrup, J, 2006)
"Rebleeding from a ruptured aneurysm increases the risk of unfavorable outcomes after subarachnoid hemorrhage (SAH) and is prevented by early aneurysm occlusion."1.91Effects of Tranexamic Acid in Patients with Subarachnoid Hemorrhage in Brazil: A Prospective Observational Study with Propensity Score Analysis. ( Bastos, LSL; Bozza, FA; Gomes, FK; Gonçalves, B; Hegele, V; Kurtz, P; Petterson, L; Rabinstein, AA; Righy, C; Rynkowski, CB; Soares, PHR; Tonello, ML; Turon, R, 2023)
"The risk of rebleeding after aneurysmal subarachnoid hemorrhage (aSAH) is the highest during the initial hours after rupture."1.91Aneurysm treatment within 6 h versus 6-24 h after rupture in patients with subarachnoid hemorrhage. ( Coert, BA; Germans, MR; Peter Vandertop, W; Post, R; Rinkel, GJ; Tjerkstra, MA; Verbaan, D; Vergouwen, MD, 2023)
"We studied 471 consecutive patients with aneurysmal subarachnoid hemorrhage and used logistic regression with step-wise forward selection of variables."1.29Amount of blood on computed tomography as an independent predictor after aneurysm rupture. ( Brouwers, PJ; Dippel, DW; Hasan, D; Lindsay, KW; van Gijn, J; Vermeulen, M, 1993)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's2 (16.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Rynkowski, CB1
Hegele, V1
Soares, PHR1
Tonello, ML1
Petterson, L1
Gomes, FK1
Rabinstein, AA1
Bastos, LSL1
Turon, R1
Gonçalves, B1
Righy, C1
Bozza, FA1
Kurtz, P1
Vergouwen, MD1
Germans, MR1
Post, R1
Tjerkstra, MA1
Coert, BA1
Rinkel, GJ1
Peter Vandertop, W1
Verbaan, D1
Larsen, CC1
Eskesen, V1
Hauerberg, J1
Olesen, C1
Romner, B1
Astrup, J3
Nakaigawa, N1
Kamata, K1
Komatsu, R1
Ozaki, M1
Hillman, J1
Fridriksson, S1
Nilsson, O1
Yu, Z1
Saveland, H1
Jakobsson, KE1
Schisano, G1
Nina, P1
Roos, Y1
Vermeulen, M2
Forssell, A1
Larsson, C1
Rönnberg, J1
Fodstad, H1
Brouwers, PJ1
Dippel, DW1
Lindsay, KW1
Hasan, D1
van Gijn, J1
Stroobandt, G1
Lambert, O1
Menard, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for tranexamic acid and Aneurysm, Ruptured

ArticleYear
["Ultra-early" antifibrinolytic treatment of subarachnoidal bleeding with tranexamic acid].
    Ugeskrift for laeger, 2006, Mar-13, Volume: 168, Issue:11

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Aortic Aneurysm; Denmark; Early Diagnosis; Emergencies;

2006
The association of tranexamic acid and nimodipine in the pre-operative treatment of ruptured intracranial aneurysms.
    Acta neurochirurgica, 1998, Volume: 140, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Antihypertensive Agents

1998

Trials

2 trials available for tranexamic acid and Aneurysm, Ruptured

ArticleYear
Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study.
    Journal of neurosurgery, 2002, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Antifibrinolytic Agents; Female; Humans; Incidence; Mal

2002
CT assessment of subarachnoid haemorrhage. A comparison between different CT methods of grading subarachnoid haemorrhage.
    British journal of neurosurgery, 1995, Volume: 9, Issue:1

    Topics: Aneurysm, Ruptured; Cerebral Angiography; Humans; Intracranial Aneurysm; Ischemic Attack, Transient;

1995

Other Studies

8 other studies available for tranexamic acid and Aneurysm, Ruptured

ArticleYear
Effects of Tranexamic Acid in Patients with Subarachnoid Hemorrhage in Brazil: A Prospective Observational Study with Propensity Score Analysis.
    Neurocritical care, 2023, Volume: 39, Issue:1

    Topics: Aneurysm, Ruptured; Brazil; Female; Humans; Male; Middle Aged; Propensity Score; Prospective Studies

2023
Aneurysm treatment within 6 h versus 6-24 h after rupture in patients with subarachnoid hemorrhage.
    European stroke journal, 2023, Volume: 8, Issue:3

    Topics: Aneurysm, Ruptured; Animals; Financial Stress; Hospitalization; Humans; Mustelidae; Subarachnoid Hem

2023
Considerable delay in diagnosis and acute management of subarachnoid haemorrhage.
    Danish medical bulletin, 2010, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Antifibrinolytic Agents; Delayed Dia

2010
[Perioperative management of a patient complicated with Quincke's edema].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:4

    Topics: Aneurysm, Ruptured; Angioedema; Chlorpheniramine; Craniotomy; Humans; Intracranial Aneurysm; Intubat

2010
[Cyclocaprone prevents early rebleeding after subarachnoid hemorrhage and should be administered already prior to transfer to the department of neurology].
    Ugeskrift for laeger, 2003, Feb-10, Volume: 165, Issue:7

    Topics: Amino Acids; Aneurysm, Ruptured; Antifibrinolytic Agents; Humans; Secondary Prevention; Subarachnoid

2003
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Critical Pathways; Dose-Response Relationship, Drug; Dr

2003
Prevention of early rebleeding.
    Journal of neurosurgery, 2003, Volume: 98, Issue:5

    Topics: Aneurysm, Ruptured; Antifibrinolytic Agents; Brain Ischemia; Glasgow Outcome Scale; Humans; Intracra

2003
Amount of blood on computed tomography as an independent predictor after aneurysm rupture.
    Stroke, 1993, Volume: 24, Issue:6

    Topics: Age Factors; Aged; Aneurysm, Ruptured; Blood; Cerebral Infarction; Double-Blind Method; Glasgow Coma

1993