Page last updated: 2024-11-05

tranexamic acid and Anemia

tranexamic acid has been researched along with Anemia in 58 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
" The primary study objective is to determine the effect of perioperative treatment with either intravenous iron, tranexamic acid or with a combination of both medicines on the reduction of intraoperative and postoperative red blood cell transfusions in gynaecological carcinoma patients."9.51Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial. ( Amstad, G; Geiger, J; Heinzelmann, V; Montavon, C; Werlen, L, 2022)
"Our aim was to compare the therapeutic efficacies of norethisterone acid (NETA), tranexamic acid and levonorgestrel-releasing intrauterine system (LNG-IUS) in treating idiopathic heavy menstrual bleeding (HMB)."9.22Comparison of Therapeutic Efficacies of Norethisterone, Tranexamic Acid and Levonorgestrel-Releasing Intrauterine System for the Treatment of Heavy Menstrual Bleeding: A Randomized Controlled Study. ( Evliyaoglu, O; Haberal, A; Kayikcioglu, F; Kiseli, M, 2016)
" The primary study objective is to determine the effect of perioperative treatment with either intravenous iron, tranexamic acid or with a combination of both medicines on the reduction of intraoperative and postoperative red blood cell transfusions in gynaecological carcinoma patients."5.51Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial. ( Amstad, G; Geiger, J; Heinzelmann, V; Montavon, C; Werlen, L, 2022)
"Our aim was to compare the therapeutic efficacies of norethisterone acid (NETA), tranexamic acid and levonorgestrel-releasing intrauterine system (LNG-IUS) in treating idiopathic heavy menstrual bleeding (HMB)."5.22Comparison of Therapeutic Efficacies of Norethisterone, Tranexamic Acid and Levonorgestrel-Releasing Intrauterine System for the Treatment of Heavy Menstrual Bleeding: A Randomized Controlled Study. ( Evliyaoglu, O; Haberal, A; Kayikcioglu, F; Kiseli, M, 2016)
" Two multivariable logistic regression models, for postoperative anemia (hemoglobin < 10 g/dL) and allogeneic blood transfusion included 8 variables: age, sex, body mass index, preoperative hemoglobin level, tranexamic acid total dose, American Society of Anesthesiologists level, operative time, and drain use."4.31Predicting Postoperative Anemia and Blood Transfusion Following Total Knee Arthroplasty. ( Ast, MP; Chalmers, BP; Della Valle, AG; Kolin, DA; Landy, DC; Lyman, S, 2023)
"Tranexamic acid is significantly less expensive than FE or EPO as a treatment option for total joint arthroplasty patients presenting with preoperative anemia."3.83Cost Analysis of Tranexamic Acid in Anemic Total Joint Arthroplasty Patients. ( Ani, F; Phan, DL; Schwarzkopf, R, 2016)
" Our aim was to assess whether the introduction of a pre-, intra-, and postoperative PBM protocol combining erythropoietin (EPO), ferric carboxymaltose (FCM), and tranexamic acid was effective in reducing perioperative transfusion and postoperative anemia."3.83Implementing a blood management protocol during the entire perioperative period allows a reduction in transfusion rate in major orthopedic surgery: a before-after study. ( Bizot, P; Chassier, C; Chaudet, A; Lasocki, S; Rineau, E, 2016)
"Tranexamic acid (TXA) has been considered effective in preventing anemia in total hip arthroplasty, but its role in hemiarthroplasty is debated."3.01Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis. ( Augustinus, S; Gardenbroek, TJ; Goslings, JC; Mulders, MAM, 2023)
"Tranexamic acid was given intravenously or topically during the perioperative period."3.01Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews. ( Estcourt, LJ; Griffin, XL; Lewis, SR; Pritchard, MW; Stanworth, SJ, 2023)
"Tranexamic acid (TXA) has been investigated further in patients with hip surgery and shows reduction of bleeding."2.82Patient blood management and patient safety. ( Steinbicker, AU; Zacharowski, K; Zoller, H, 2022)
"Tranexamic acid is an antifibrinolytic agent that has been widely used in other surgical specialties, especially in cardiac, orthopedic, and trauma surgery."2.58The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations. ( Cho, MJ; Rohrich, RJ, 2018)
"Fibrin sealant also has this potential, but is not more potent than tranexamic acid."2.52Prevention of post-operative anaemia in hip and knee arthroplasty--a systematic review. ( Husted, H; Khan, N; Troelsen, A, 2015)
"Future treatment of trauma-induced coagulopathy may be based on systemic antifibrinolytics, local haemostatics and individualized point-of-care-guided rational use of coagulation factor concentrates such as fibrinogen, prothrombin complex concentrate, recombinant factor VIIa and factor XIII."2.48Emerging treatment strategies for trauma-induced coagulopathy. ( Fries, D; Sorensen, B, 2012)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (3.45)29.6817
2010's38 (65.52)24.3611
2020's18 (31.03)2.80

Authors

AuthorsStudies
Brenner, A1
Roberts, I4
Balogun, E3
Bello, FA1
Chaudhri, R3
Fleming, C1
Javaid, K2
Kayani, A2
Lubeya, MK1
Mansukhani, R1
Olayemi, O1
Prowse, D2
Vwalika, B2
Shakur-Still, H3
Amstad, G1
Geiger, J1
Werlen, L1
Montavon, C1
Heinzelmann, V1
Zacharowski, K1
Zoller, H1
Steinbicker, AU1
Augustinus, S2
Mulders, MAM2
Gardenbroek, TJ2
Goslings, JC2
Kolin, DA2
Lyman, S1
Della Valle, AG1
Ast, MP2
Landy, DC1
Chalmers, BP2
Lewis, SR1
Pritchard, MW1
Estcourt, LJ1
Stanworth, SJ1
Griffin, XL1
Jung, HJ1
Kang, MW1
Lee, JH1
Lee, JK1
Kim, JI1
Lasocki, S3
Capdevila, X2
Vielle, B2
Bijok, B1
Lahlou-Casulli, M2
Collange, V2
Grillot, N1
Danguy des Deserts, M2
Duchalais, A2
Delannoy, B1
Drugeon, B2
Bouzat, P2
David, JS2
Rony, L1
Loupec, T2
Léger, M2
Rineau, E3
Sculco, PK1
Gonzalez Della Valle, A1
Rodriguez, JA1
Hourlier, H1
Fennema, P1
Zhao, M1
Geng, X1
Wang, C1
Zeng, L1
Tian, H1
Lloyd, TD1
Neal-Smith, G1
Fennelly, J1
Claireaux, H1
Bretherton, C1
Carr, AJ1
Murphy, M1
Kendrick, BJ1
Palmer, AJR1
Picetti, R1
Miller, L1
Pepple, T2
Beaumont, D2
Asonganyi, E1
El-Sheikh, M1
Arulkumaran, S2
Biboulet, P1
Motais, C1
Pencole, M1
Karam, O1
Dangelser, G1
Smilevitch, P1
Maissiat, G1
Bringuier, S1
Scrimshire, AB2
Fairhurst, C2
McDaid, C2
Torgerson, DJ2
Al-Samkari, H1
Parot-Schinkel, E1
Roquilly, A1
Desebbe, O1
Garrigue, D1
Mounet, B1
Hamard, F1
Pempe, C1
Werdehausen, R1
Pieroh, P1
Federbusch, M1
Petros, S1
Henschler, R1
Roth, A1
Pfrepper, C1
Cybulska, P1
Goss, C1
Tew, WP1
Parameswaran, R1
Sonoda, Y1
Alexander, DP1
Frew, N1
Klement, MR2
Peres-Da-Silva, A1
Nickel, BT1
Green, CL4
Wellman, SS2
Attarian, DE1
Bolognesi, MP3
Seyler, TM4
Rohrich, RJ1
Cho, MJ1
Olaussen, A1
Bade-Boon, J1
Fitzgerald, MC1
Mitra, B1
Zhang, S1
Huang, Q1
Xu, B1
Ma, J1
Cao, G1
Pei, F1
Polanco-García, M1
Capielo, AM1
Miret, X1
Chamero, A1
Sainz, J1
Revilla, E1
Guinjoan, A1
Arranz, T1
Kildow, BJ2
Howell, EP2
Karas, V2
Baumgartner, WT1
Cunningham, DJ2
Pavenski, K1
Ward, SE1
Hare, GMT1
Freedman, J1
Pulendrarajah, R1
Pirani, RA1
Sheppard, N1
Vance, C1
White, A1
Lo, N1
Waddell, JP1
Ho, A1
Schemitsch, EH1
Kataoka, M1
Bogoch, ER1
Saini, K1
David Mazer, C1
Baker, JE1
Halawi, MJ1
Plourde, JM1
Cote, MP1
Ker, K2
Fawole, B1
Bates, I1
Wolfson, TS1
Novikov, D1
Chen, KK1
Kim, KY1
Anoushiravani, AA1
Deshmukh, AJ1
Lajam, CM1
Lemoine, A1
Lambaudie, E1
Bonnet, F1
Leblanc, E1
Alfonsi, P1
Sun, Q1
Li, J1
Chen, J1
Zheng, C1
Liu, C1
Jia, Y1
Ryan, SP2
Blizzard, DJ1
Wu, XD1
Xiao, PC1
Zhu, ZL1
Liu, JC1
Li, YJ1
Huang, W1
Abeysiri, S1
Chau, M1
Highton, D1
Richards, T1
Theusinger, OM1
Stein, P1
Spahn, DR1
Bagsby, DT1
Hur, J1
Schwameis, M1
Thaler, J1
Schober, A1
Schörgenhofer, C1
Kulinna-Cosentini, C1
Laggner, A1
Röggla, M1
Jilma, B1
Albinarrate, A1
López-Picado, A1
Oiartzabal, I1
López-Ariznabarreta, C1
Molano, J1
Barrachina, B1
Muñoz Gómez, M1
Bisbe Vives, E1
Basora Macaya, M1
García Erce, JA1
Gómez Luque, A1
Leal-Noval, SR1
Colomina, MJ1
Comin Colet, J1
Contreras Barbeta, E1
Cuenca Espiérrez, J1
Garcia de Lorenzo Y Mateos, A1
Gomollón García, F1
Izuel Ramí, M1
Moral García, MV1
Montoro Ronsano, JB1
Páramo Fernández, JA1
Pereira Saavedra, A1
Quintana Diaz, M1
Remacha Sevilla, Á1
Salinas Argente, R1
Sánchez Pérez, C1
Tirado Anglés, G1
Torrabadella de Reinoso, P1
Holt, JB1
Miller, BJ1
Callaghan, JJ1
Clark, CR1
Willenborg, MD1
Noiseux, NO1
Sizer, SC1
Cherian, JJ1
Elmallah, RD1
Pierce, TP1
Beaver, WB1
Mont, MA1
Phan, DL1
Ani, F1
Schwarzkopf, R1
Khan, N1
Troelsen, A1
Husted, H1
Chaudet, A1
Chassier, C1
Bizot, P1
Kopanidis, P1
Hardidge, A1
McNicol, L1
Tay, S1
McCall, P1
Weinberg, L1
Kiseli, M1
Kayikcioglu, F1
Evliyaoglu, O1
Haberal, A1
Park, KJ1
Couch, CG1
Edwards, PK1
Siegel, ER1
Mears, SC1
Barnes, CL1
Suh, DW1
Han, SB1
Park, JH1
Cheong, K1
Kyung, BS1
Kasparek, MF1
Faschingbauer, M1
Waldstein, W1
Boettner, CS1
Boettner, F1
Styron, JF1
Klika, AK1
Szubski, CR1
Tolich, D1
Barsoum, WK1
Higuera, CA1
Rosencher, N1
Bellamy, L1
Chabbouh, T1
Arnaout, L1
Ozier, Y1
Ahn, SW1
Shim, JK1
Youn, YN1
Song, JW1
Yang, SY1
Chung, SC1
Kwak, YL1
Sorensen, B1
Fries, D1
Watts, CD1
Pagnano, MW1
Murphy, DP1
O'Donnell, T1
McDonnell, J1
McElwain, JP1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid for the Prevention of Postpartum Bleeding in Women With Anaemia: an International, Randomised, Double-blind, Placebo Controlled Trial.[NCT03475342]Phase 315,000 participants (Anticipated)Interventional2019-08-24Recruiting
Serum Hepcidin and Iron Status Parameters in Pregnant Women and the Association With Adverse Maternal and Fetal Outcome[NCT03792464]188 participants (Actual)Observational2019-04-30Completed
Iron Prehabilitation and Perioperative Infectious Diseases of Endometrial Cancer Patients[NCT06049693]Phase 4100 participants (Anticipated)Interventional2023-01-01Enrolling by invitation
HiFIT Study: Interest of Intravenous Iron and Tranexamic Acid to Reduce Transfusion in Hip Fracture Patients[NCT02972294]Phase 3419 participants (Actual)Interventional2017-03-31Terminated (stopped due to 1year inclusion hold due to PV new fact (Monofer hold for risk revaluation) DSMB Interim analysis : 1treatment with important transfusion risk reduction/inclusions issues (COVID)/sites change of practice if study continue=>stop inclusions)
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
Use of TRanEXamic Acid in Reduction Mammoplasty (TREX-ARM): a Double-blinded Randomized Controlled Trial[NCT04947514]Phase 498 participants (Actual)Interventional2021-10-29Completed
Role of Tranexamic Acid (TXA) in the Reduction of Post-operative Hematoma and Seroma in Patients Undergoing Panniculectomy or Abdominoplasty, a Pilot Study.[NCT04902950]Phase 49 participants (Actual)Interventional2020-08-17Terminated (stopped due to Logistics)
Use of Tranexamic Acid in Liposculpture: A Double-blind, Multicenter, Randomized Trial[NCT04430777]Phase 2/Phase 3141 participants (Actual)Interventional2019-01-17Completed
Extended Postoperative Tranexamic Acid Use in Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial[NCT05099276]Phase 446 participants (Actual)Interventional2021-12-07Active, not recruiting
"Change in Transfusion Rates of Patients Undergoing Elective Total Hip Replacement Before/After the Implementation of a Peri-operative Patient Blood Management Program: a Retrospective Observational Study."[NCT04398238]400 participants (Actual)Observational2021-08-01Completed
Prospective Randomized Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty[NCT03359525]Phase 4114 participants (Anticipated)Interventional2017-07-01Recruiting
Estimation of Coagulation Factor XIII Activity Based on the Initial Plasma Fibrinogen Level in Trauma[NCT03634215]357 participants (Actual)Observational2018-09-01Completed
Efficacy and Safety of Erythropoietin And/Or Intravenous Iron Sucrose For Treatment of Anemia In Hip and Knee Arthroplasty: A Single-center Retrospective Study[NCT03917394]780 participants (Anticipated)Observational2019-04-24Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Breasts With Development of Hematoma

The number of breasts with clinically significant hematoma (collection of blood under the skin) requiring either conservative management or operative washout was determined. (NCT04947514)
Timeframe: Up to 30 days

Interventionbreasts (Number)
Treatment Side (Right or Left)2
Placebo Side (Right or Left)1

Number of Participants Requiring a Blood Transfusion

The number of participants requiring blood transfusion was based on the postoperative decline in hematocrit level (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Number of Participants With Deep Vein Thrombosis/Venous Thromboembolism

Incidence of clinically significant deep vein thrombosis or pulmonary embolism detected on imaging (ultrasound or CT scan) (NCT04947514)
Timeframe: Up to 30 days

InterventionParticipants (Count of Participants)
Treatment Side (Right or Left)0
Placebo Side (Right or Left)0

Number of Days Until Drain Removal

The number of days that the post surgical drains remain in place after the surgery. When less than 30 cc per drain in a 24-hour period, the participants are to call and schedule drain removal. (NCT04902950)
Timeframe: Up to 56 days post operatively.

InterventionDays (Mean)
Group 116
Group 222

Number of Participants That Returned to the Operating Room

Return to the operating room for evacuation post surgical operative hematoma or seroma assessed by clinical evaluation to include palpation for ballotable fluid collection and assessment of skin for a shiny/tight appearance suggestive of an underlying fluid collection. (NCT04902950)
Timeframe: Up to 8 weeks postoperatively

InterventionParticipants (Count of Participants)
Group 10
Group 20

Participants With Post Operative Hematoma

Patients will be monitored clinically at each post-operative visit for signs of post-operative hematoma or seroma. Each patient will be evaluated one week, three weeks, and eight weeks following their procedure to assess overall wound healing. (NCT04902950)
Timeframe: Up to 8 weeks postoperatively

InterventionParticipants (Count of Participants)
Group 10
Group 21

Reviews

17 reviews available for tranexamic acid and Anemia

ArticleYear
Patient blood management and patient safety.
    Current opinion in anaesthesiology, 2022, Dec-01, Volume: 35, Issue:6

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Humans; Patient Safety; Tranexamic Acid

2022
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Tranexamic acid in hip hemiarthroplasty surgery: a systematic review and meta-analysis.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023, Volume: 49, Issue:3

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Loss, Surgical; Hemiar

2023
Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery: an overview of systematic reviews.
    The Cochrane database of systematic reviews, 2023, 06-08, Volume: 6

    Topics: Aged; Anemia; Emergence Delirium; Erythrocyte Transfusion; Hemorrhage; Hip Fractures; Humans; Iron;

2023
Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care.
    Blood, 2021, 02-18, Volume: 137, Issue:7

    Topics: Anemia; Angiogenesis Inhibitors; Anticoagulants; Antifibrinolytic Agents; Clinical Trials as Topic;

2021
Indications for and complications of transfusion and the management of gynecologic malignancies.
    Gynecologic oncology, 2017, Volume: 146, Issue:2

    Topics: Acute Lung Injury; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Transfusion; F

2017
Preoperative optimisation of anaemia for primary total hip arthroplasty: a systematic review.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2017, Nov-21, Volume: 27, Issue:6

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Erythropoietin;

2017
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
The Role of Tranexamic Acid in Plastic Surgery: Review and Technical Considerations.
    Plastic and reconstructive surgery, 2018, Volume: 141, Issue:2

    Topics: Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedure

2018
[Perioperative care of epithelial ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF a
    Gynecologie, obstetrique, fertilite & senologie, 2019, Volume: 47, Issue:2

    Topics: Analgesia, Patient-Controlled; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Carcinoma, Ova

2019
Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials.
    BMJ open, 2019, 01-28, Volume: 9, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Anemia; Antifibrinolytic Agents; Arthroplasty,

2019
Management of the patient presenting with anaemia in the preoperative setting.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2019, Volume: 58, Issue:4

    Topics: Anemia; Blood Loss, Surgical; Erythrocyte Transfusion; Humans; Operative Blood Salvage; Preoperative

2019
Applying 'Patient Blood Management' in the trauma center.
    Current opinion in anaesthesiology, 2014, Volume: 27, Issue:2

    Topics: Anemia; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Transfusion; Deamino Arginine

2014
Predicting Blood Loss in Total Knee and Hip Arthroplasty.
    The Orthopedic clinics of North America, 2015, Volume: 46, Issue:4

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2015
Prevention of post-operative anaemia in hip and knee arthroplasty--a systematic review.
    Danish medical journal, 2015, Volume: 62, Issue:12

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, K

2015
[Blood conservation approaches in orthopedic surgery].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2008, Volume: 15, Issue:5

    Topics: Anemia; Aprotinin; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Autologous; Drug Admi

2008
Emerging treatment strategies for trauma-induced coagulopathy.
    The British journal of surgery, 2012, Volume: 99 Suppl 1

    Topics: Acidosis; Anemia; Antifibrinolytic Agents; Bandages; Blood Coagulation Disorders; Blood Coagulation

2012
Minimising blood loss and transfusion in contemporary hip and knee arthroplasty.
    The Journal of bone and joint surgery. British volume, 2012, Volume: 94, Issue:11 Suppl A

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2012
Treatment of anaemia in the polytrauma Jehovah's Witness.
    Irish medical journal, 2003, Volume: 96, Issue:1

    Topics: Anemia; Antifibrinolytic Agents; Blood Substitutes; Blood Transfusion; Fluorocarbons; Hemodilution;

2003

Trials

8 trials available for tranexamic acid and Anemia

ArticleYear
Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial.
    BMJ open, 2022, 09-26, Volume: 12, Issue:9

    Topics: Anemia; Blood Transfusion; Carcinoma; Female; Ferric Compounds; Gynecologic Surgical Procedures; Hum

2022
Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial.
    BMJ open, 2022, 09-26, Volume: 12, Issue:9

    Topics: Anemia; Blood Transfusion; Carcinoma; Female; Ferric Compounds; Gynecologic Surgical Procedures; Hum

2022
Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial.
    BMJ open, 2022, 09-26, Volume: 12, Issue:9

    Topics: Anemia; Blood Transfusion; Carcinoma; Female; Ferric Compounds; Gynecologic Surgical Procedures; Hum

2022
Perioperative management with ferric carboxymaltose and tranexamic acid to reduce transfusion rate in gynaecological carcinoma surgery (TRANAFER-Study): study protocol for a single-blind, monocentre, randomised trial.
    BMJ open, 2022, 09-26, Volume: 12, Issue:9

    Topics: Anemia; Blood Transfusion; Carcinoma; Female; Ferric Compounds; Gynecologic Surgical Procedures; Hum

2022
Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial): a multicentre, 2 × 2 factorial, randomised, double-blind, controlled trial.
    The Lancet. Haematology, 2023, Volume: 10, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Blood Transfusion; Double-Blind Method; Female; Hemoglobins;

2023
The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries.
    BMC pregnancy and childbirth, 2020, Jul-16, Volume: 20, Issue:1

    Topics: Adult; Africa; Anemia; Antifibrinolytic Agents; Asia; Blood Transfusion; Cause of Death; Cesarean Se

2020
Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study.
    Transfusion, 2020, Volume: 60, Issue:8

    Topics: Aged; Anemia; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Transfusion; Er

2020
Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study).
    BMJ open, 2021, 01-17, Volume: 11, Issue:1

    Topics: Administration, Intravenous; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusio

2021
Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial.
    Trials, 2018, Dec-29, Volume: 19, Issue:1

    Topics: Africa; Anemia; Antifibrinolytic Agents; Asia; Biomarkers; Double-Blind Method; Female; Hemoglobins;

2018
Comparison of Therapeutic Efficacies of Norethisterone, Tranexamic Acid and Levonorgestrel-Releasing Intrauterine System for the Treatment of Heavy Menstrual Bleeding: A Randomized Controlled Study.
    Gynecologic and obstetric investigation, 2016, Volume: 81, Issue:5

    Topics: Adult; Anemia; Female; Hemostatics; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Menorrh

2016
Effect of tranexamic acid on transfusion requirement in dual antiplatelet-treated anemic patients undergoing off-pump coronary artery bypass graft surgery.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:1

    Topics: Aged; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Blood Transfusion; Comorbidity; Coronar

2012

Other Studies

33 other studies available for tranexamic acid and Anemia

ArticleYear
Postpartum haemorrhage in anaemic women: assessing outcome measures for clinical trials.
    Trials, 2022, Mar-18, Volume: 23, Issue:1

    Topics: Anemia; Delivery, Obstetric; Female; Humans; Outcome Assessment, Health Care; Postpartum Hemorrhage;

2022
Predicting Postoperative Anemia and Blood Transfusion Following Total Knee Arthroplasty.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:7

    Topics: Aged; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood

2023
The Association of Intravenous Iron Administered the Day before Total Knee Arthroplasty with Postoperative Anemia and Functional Recovery.
    Medicina (Kaunas, Lithuania), 2023, Jun-28, Volume: 59, Issue:7

    Topics: Anemia; Anemia, Iron-Deficiency; Arthroplasty, Replacement, Knee; Ferritins; Hemoglobins; Humans; Re

2023
Risk factors for blood transfusion and postoperative anaemia following total knee arthroplasty.
    The bone & joint journal, 2023, Oct-01, Volume: 105-B, Issue:10

    Topics: Aged; Anemia; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transfusion; Female; Hemo

2023
An observational study of an adjusted patient blood management protocol intended to lower rates of transfusion following total knee arthroplasty in patients with preoperative anemia.
    Journal of orthopaedic surgery and research, 2023, Dec-02, Volume: 18, Issue:1

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Blood Transf

2023
The value of tranexamic acid for patients with preoperative anemia in primary total knee arthroplasty.
    European journal of medical research, 2019, Aug-12, Volume: 24, Issue:1

    Topics: Aged; Anemia; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Chi-Square Distribution; Female

2019
Peri-operative administration of tranexamic acid in lower limb arthroplasty: a multicentre, prospective cohort study.
    Anaesthesia, 2020, Volume: 75, Issue:8

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement; Arthroplasty, R

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Effectiveness of pre-operative anaemia screening and increased Tranexamic acid dose policies on outcomes following unilateral primary, elective total hip or knee replacement: a statistical analysis plan for an interrupted time series and regression discon
    F1000Research, 2020, Volume: 9

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bl

2020
Predictors for blood loss and transfusion frequency to guide blood saving programs in primary knee- and hip-arthroplasty.
    Scientific reports, 2021, 02-23, Volume: 11, Issue:1

    Topics: Aged; Anemia; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bioma

2021
What Should Define Preoperative Anemia in Primary THA?
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:11

    Topics: Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Biomarkers; Blood Loss, Surgical;

2017
Management of injured patients who were Jehovah's Witnesses, where blood transfusion may not be an option: a retrospective review.
    Vox sanguinis, 2018, Volume: 113, Issue:3

    Topics: Anemia; Australia; Blood Transfusion; Erythropoietin; Female; Hemorrhage; Humans; Jehovah's Witnesse

2018
Effectiveness and safety of an optimized blood management program in total hip and knee arthroplasty: A large, single-center, retrospective study.
    Medicine, 2018, Volume: 97, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Adult; Aged; Anemia; Antifibrinolytic Agents;

2018
Effectiveness of a patient blood management protocol on reduction of allogeneic red blood cell transfusions in orthopedic surgery.
    Medicina clinica, 2019, 02-01, Volume: 152, Issue:3

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplas

2019
When Should Complete Blood Count Tests Be Performed in Primary Total Hip Arthroplasty Patients?
    The Journal of arthroplasty, 2018, Volume: 33, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blo

2018
A rationale for universal tranexamic acid in major joint arthroplasty: overall efficacy and impact of risk factors for transfusion.
    Transfusion, 2019, Volume: 59, Issue:1

    Topics: Anemia; Antifibrinolytic Agents; Blood Transfusion; Body Mass Index; Erythrocytes; Female; Humans; L

2019
Routine Postoperative Laboratory Tests Are Not Necessary After Primary Total Hip Arthroplasty.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Aged; Anemia; Arthroplasty, Replacement, Hip; Blood Chemical Analysis; Blood Lo

2019
Total Knee Arthroplasty Is Safe in Jehovah's Witness Patients-A 12-Year Perspective.
    The journal of knee surgery, 2020, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Los

2020
Preoperative Hemoglobin Predicts Postoperative Transfusion Despite Antifibrinolytics During Total Knee Arthroplasty.
    Orthopedics, 2019, Mar-01, Volume: 42, Issue:2

    Topics: Age Factors; Aged; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Transfusi

2019
Clinical Impact of Routine Complete Blood Counts Following Total Knee Arthroplasty.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:7S

    Topics: Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Cel

2019
The necessity of routine postoperative laboratory tests in enhanced recovery after surgery for primary hip and knee arthroplasty: A retrospective cohort study protocol.
    Medicine, 2019, Volume: 98, Issue:18

    Topics: Adult; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, K

2019
Effect of intra-articular injection of tranexamic acid on postoperative hemoglobin in total hip arthroplasty.
    Orthopedics, 2014, Volume: 37, Issue:6

    Topics: Aged; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blood Transfusion; Female; He

2014
Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings.
    Thrombosis and haemostasis, 2014, Volume: 112, Issue:5

    Topics: Adenocarcinoma; Aged; Anemia; Antifibrinolytic Agents; Antineoplastic Combined Chemotherapy Protocol

2014
Assessment of the introduction of a blood management program in orthopaedic surgery.
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:8

    Topics: Aged; Anemia; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biomarkers; Blood Ban

2015
Forum for debate: Safety of allogeneic blood transfusion alternatives in the surgical/critically ill patient.
    Medicina intensiva, 2015, Volume: 39, Issue:9

    Topics: Anemia; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Factors; Blood Transfusion; Clinical T

2015
Minimizing Blood Transfusion in Total Hip and Knee Arthroplasty Through a Multimodal Approach.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:2

    Topics: Aged; Aged, 80 and over; Algorithms; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip

2016
Cost Analysis of Tranexamic Acid in Anemic Total Joint Arthroplasty Patients.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:3

    Topics: Aged; Anemia; Antifibrinolytic Agents; Arthroplasty; Blood Loss, Surgical; Blood Transfusion; Cost-B

2016
Implementing a blood management protocol during the entire perioperative period allows a reduction in transfusion rate in major orthopedic surgery: a before-after study.
    Transfusion, 2016, Volume: 56, Issue:3

    Topics: Adult; Anemia; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Transfusion; C

2016
Perioperative blood management programme reduces the use of allogenic blood transfusion in patients undergoing total hip and knee arthroplasty.
    Journal of orthopaedic surgery and research, 2016, Feb-29, Volume: 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replaceme

2016
Tranexamic Acid Reduces Blood Transfusions in Revision Total Hip Arthroplasty.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Blo

2016
Intravenous iron supplementation with intra-articular administration of tranexamic acid reduces the rate of allogeneic transfusions after simultaneous bilateral total knee arthroplasty.
    Blood transfusion = Trasfusione del sangue, 2017, Volume: 15, Issue:6

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplasty,

2017
Topical Tranexamic Acid is Equivalent to Targeted Preoperative Autologous Blood Donation in Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:4

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anemia; Antifibrinolytic Agents; Arthroplas

2017
Relative efficacy of tranexamic acid and preoperative anemia treatment for reducing transfusions in total joint arthroplasty.
    Transfusion, 2017, Volume: 57, Issue:3

    Topics: Aged; Anemia; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Transfusion; Fe

2017
Tranexamic acid for postpartum bleeding.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2011, Volume: 115, Issue:3

    Topics: Anemia; Antifibrinolytic Agents; Cesarean Section; Female; Humans; Postpartum Hemorrhage; Pregnancy;

2011